Result of FASTA (omim) for pF1KB7221
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KB7221, 207 aa
  1>>>pF1KB7221 207 - 207 aa - 207 aa
Library: /omim/omim.rfq.tfa
  60827320 residues in 85289 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 6.0991+/-0.000368; mu= 11.0292+/- 0.023
 mean_var=98.7135+/-20.010, 0's: 0 Z-trim(115.3): 20  B-trim: 0 in 0/54
 Lambda= 0.129088
 statistics sampled from 25584 (25604) to 25584 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.679), E-opt: 0.2 (0.3), width:  16
 Scan time:  4.090

The best scores are:                                      opt bits E(85289)
NP_064509 (OMIM: 615326) interferon kappa precurso ( 207) 1410 272.4 3.6e-73
NP_002167 (OMIM: 147640) interferon beta precursor ( 187)  186 44.5 0.00014
NP_067091 (OMIM: 147583) interferon alpha-17 precu ( 189)  173 42.0 0.00074
NP_002168 (OMIM: 147553) interferon omega-1 precur ( 195)  170 41.5  0.0011
NP_066546 (OMIM: 147564) interferon alpha-4 precur ( 189)  168 41.1  0.0014
NP_002166 (OMIM: 147584) interferon alpha-21 precu ( 189)  164 40.4  0.0024
NP_002163 (OMIM: 147579) interferon alpha-14 precu ( 189)  163 40.2  0.0027
NP_002162 (OMIM: 147577) interferon alpha-10 precu ( 189)  163 40.2  0.0027
NP_076918 (OMIM: 147660) interferon alpha-1/13 pre ( 189)  162 40.0  0.0031
NP_008831 (OMIM: 147578) interferon alpha-1/13 pre ( 190)  162 40.0  0.0031
NP_795372 (OMIM: 615223) interferon epsilon precur ( 208)  162 40.0  0.0033
NP_066401 (OMIM: 147567) interferon alpha-7 precur ( 189)  160 39.6   0.004
NP_066282 (OMIM: 147566) interferon alpha-6 precur ( 189)  159 39.4  0.0045
NP_002160 (OMIM: 147565) interferon alpha-5 precur ( 189)  159 39.4  0.0045
NP_000596 (OMIM: 147562) interferon alpha-2 precur ( 188)  158 39.2  0.0051
NP_002164 (OMIM: 147580) interferon alpha-16 precu ( 189)  158 39.2  0.0051


>>NP_064509 (OMIM: 615326) interferon kappa precursor [H  (207 aa)
 initn: 1410 init1: 1410 opt: 1410  Z-score: 1434.7  bits: 272.4 E(85289): 3.6e-73
Smith-Waterman score: 1410; 100.0% identity (100.0% similar) in 207 aa overlap (1-207:1-207)

               10        20        30        40        50        60
pF1KB7 MSTKPDMIQKCLWLEILMGIFIAGTLSLDCNLLNVHLRRVTWQNLRHLSSMSNSFPVECL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_064 MSTKPDMIQKCLWLEILMGIFIAGTLSLDCNLLNVHLRRVTWQNLRHLSSMSNSFPVECL
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB7 RENIAFELPQEFLQYTQPMKRDIKKAFYEMSLQAFNIFSQHTFKYWKERHLKQIQIGLDQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_064 RENIAFELPQEFLQYTQPMKRDIKKAFYEMSLQAFNIFSQHTFKYWKERHLKQIQIGLDQ
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB7 QAEYLNQCLEEDKNENEDMKEMKENEMKPSEARVPQLSSLELRRYFHRIDNFLKEKKYSD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_064 QAEYLNQCLEEDKNENEDMKEMKENEMKPSEARVPQLSSLELRRYFHRIDNFLKEKKYSD
              130       140       150       160       170       180

              190       200       
pF1KB7 CAWEIVRVEIRRCLYYFYKFTALFRRK
       :::::::::::::::::::::::::::
NP_064 CAWEIVRVEIRRCLYYFYKFTALFRRK
              190       200       

>>NP_002167 (OMIM: 147640) interferon beta precursor [Ho  (187 aa)
 initn: 327 init1: 176 opt: 186  Z-score: 203.4  bits: 44.5 E(85289): 0.00014
Smith-Waterman score: 337; 34.0% identity (62.5% similar) in 200 aa overlap (7-205:1-186)

               10        20        30        40        50        60
pF1KB7 MSTKPDMIQKCLWLEILMGIFIAGTLSLDCNLLNVHLRRVTWQNLRHLSSMSNSFPVECL
             : .:::    :.  : . .::.. :::.   :  ..:  . : .... .   ::
NP_002       MTNKCLLQIALLLCFSTTALSMSYNLLGFLQRSSNFQCQKLLWQLNGRLEY-CL
                     10        20        30        40        50    

               70        80        90       100        110         
pF1KB7 RENIAFELPQEFLQYTQPMKRDIKKAFYEMSLQAFNIFSQHTFKY-WKERHLKQIQIGLD
       .. . :..:.:. :  : .:.:   ..:::  . : :: : . .  :.:  ....  .. 
NP_002 KDRMNFDIPEEIKQLQQFQKEDAALTIYEMLQNIFAIFRQDSSSTGWNETIVENLLANVY
            60        70        80        90       100       110   

     120       130       140       150       160       170         
pF1KB7 QQAEYLNQCLEEDKNENEDMKEMKENEMKPSEARVPQLSSLELRRYFHRIDNFLKEKKYS
       .: ..:.  ::: : :.::. . :             .:::.:.::. :: ..:: :.::
NP_002 HQINHLKTVLEE-KLEKEDFTRGK------------LMSSLHLKRYYGRILHYLKAKEYS
           120        130                   140       150       160

     180       190       200       
pF1KB7 DCAWEIVRVEIRRCLYYFYKFTALFRRK
        ::: :::::: : .:.. ..:. .:  
NP_002 HCAWTIVRVEILRNFYFINRLTGYLRN 
              170       180        

>>NP_067091 (OMIM: 147583) interferon alpha-17 precursor  (189 aa)
 initn: 263 init1: 173 opt: 173  Z-score: 190.2  bits: 42.0 E(85289): 0.00074
Smith-Waterman score: 297; 32.0% identity (60.0% similar) in 200 aa overlap (12-207:3-188)

               10        20           30        40        50       
pF1KB7 MSTKPDMIQKCLWLEILMGIFI---AGTLSLDCNLLNVHLRRVTWQNLRHLSSMSNSFPV
                  : . .::....    .  :: :.: ..:    . . :  :..:.   : 
NP_067          MALSFSLLMAVLVLSYKSICSLGCDLPQTH-SLGNRRALILLAQMGRISPF
                        10        20        30         40        50

        60        70        80        90        100       110      
pF1KB7 ECLRENIAFELPQEFLQYTQPMKRDIKKAFYEMSLQAFNIFS-QHTFKYWKERHLKQIQI
        ::..   : :::: .. .: .: .  ....::  :.::.:: . .   :..  :.... 
NP_067 SCLKDRHDFGLPQEEFDGNQFQKTQAISVLHEMIQQTFNLFSTEDSSAAWEQSLLEKFST
               60        70        80        90       100       110

        120       130       140       150       160       170      
pF1KB7 GLDQQAEYLNQCLEEDKNENEDMKEMKENEMKPSEARVPQLSSLELRRYFHRIDNFLKEK
        : :: . :. :. .. .  :.   :.:.            : : .:.::.::  .: ::
NP_067 ELYQQLNNLEACVIQEVGM-EETPLMNED------------SILAVRKYFQRITLYLTEK
              120        130                   140       150       

        180       190       200        
pF1KB7 KYSDCAWEIVRVEIRRCLYYFYKFTALFRRK 
       ::: ::::.::.:: : : .  ..  ..::: 
NP_067 KYSPCAWEVVRAEIMRSLSFSTNLQKILRRKD
       160       170       180         

>>NP_002168 (OMIM: 147553) interferon omega-1 precursor   (195 aa)
 initn: 278 init1: 163 opt: 170  Z-score: 187.0  bits: 41.5 E(85289): 0.0011
Smith-Waterman score: 316; 34.2% identity (60.9% similar) in 184 aa overlap (27-207:21-188)

               10        20        30          40        50        
pF1KB7 MSTKPDMIQKCLWLEILMGIFIAGTLSLDCNLLNVH--LRRVTWQNLRHLSSMSNSFPVE
                                 :: :.: . :  : : :   :...  .:   :  
NP_002       MALLFPLLAALVMTSYSPVGSLGCDLPQNHGLLSRNTLVLLHQMRRIS---PFL
                     10        20        30        40           50 

       60        70        80        90        100       110       
pF1KB7 CLRENIAFELPQEFLQYTQPMKRDIKKAFYEMSLQAFNIF-SQHTFKYWKERHLKQIQIG
       ::..   :..:::... .: .:  . ....::  : :..: ....   :.   : :.. :
NP_002 CLKDRRDFRFPQEMVKGSQLQKAHVMSVLHEMLQQIFSLFHTERSSAAWNMTLLDQLHTG
              60        70        80        90       100       110 

       120       130       140       150       160       170       
pF1KB7 LDQQAEYLNQCLEEDKNENEDMKEMKENEMKPSEARVPQLSSLELRRYFHRIDNFLKEKK
       : :: ..:. :: .  .:.:.   ..    .:.         : :::::. :  .:::::
NP_002 LHQQLQHLETCLLQVVGEGESAGAIS----SPA---------LTLRRYFQGIRVYLKEKK
             120       130           140                150        

       180       190       200              
pF1KB7 YSDCAWEIVRVEIRRCLYYFYKFTALFRRK       
       :::::::.::.:: . :.   ..   .: :       
NP_002 YSDCAWEVVRMEIMKSLFLSTNMQERLRSKDRDLGSS
      160       170       180       190     

>>NP_066546 (OMIM: 147564) interferon alpha-4 precursor   (189 aa)
 initn: 238 init1: 168 opt: 168  Z-score: 185.2  bits: 41.1 E(85289): 0.0014
Smith-Waterman score: 266; 30.5% identity (58.5% similar) in 200 aa overlap (12-207:3-188)

               10        20           30        40        50       
pF1KB7 MSTKPDMIQKCLWLEILMGIFI---AGTLSLDCNLLNVHLRRVTWQNLRHLSSMSNSFPV
                  : . .::....    .  :: :.: ..:    . . :  :..:.     
NP_066          MALSFSLLMAVLVLSYKSICSLGCDLPQTH-SLGNRRALILLAQMGRISHF
                        10        20        30         40        50

        60        70        80        90        100       110      
pF1KB7 ECLRENIAFELPQEFLQYTQPMKRDIKKAFYEMSLQAFNIFS-QHTFKYWKERHLKQIQI
        ::..   : .:.: ..  : .: .  ....::  :.::.:: . .   :..  :.... 
NP_066 SCLKDRHDFGFPEEEFDGHQFQKAQAISVLHEMIQQTFNLFSTEDSSAAWEQSLLEKFST
               60        70        80        90       100       110

        120       130       140       150       160       170      
pF1KB7 GLDQQAEYLNQCLEEDKNENEDMKEMKENEMKPSEARVPQLSSLELRRYFHRIDNFLKEK
        : :: . :. :. .. .  :.   :.:.            : : .:.::.::  .: ::
NP_066 ELYQQLNDLEACVIQEVGV-EETPLMNED------------SILAVRKYFQRITLYLTEK
              120        130                   140       150       

        180       190       200        
pF1KB7 KYSDCAWEIVRVEIRRCLYYFYKFTALFRRK 
       ::: ::::.::.:: : : .  ..   .::: 
NP_066 KYSPCAWEVVRAEIMRSLSFSTNLQKRLRRKD
       160       170       180         

>>NP_002166 (OMIM: 147584) interferon alpha-21 precursor  (189 aa)
 initn: 244 init1: 159 opt: 164  Z-score: 181.2  bits: 40.4 E(85289): 0.0024
Smith-Waterman score: 272; 30.5% identity (58.5% similar) in 200 aa overlap (12-207:3-188)

               10        20           30        40        50       
pF1KB7 MSTKPDMIQKCLWLEILMGIFI---AGTLSLDCNLLNVHLRRVTWQNLRHLSSMSNSFPV
                  : . .::....    .  :: :.: ..:    . . :  :..:.   : 
NP_002          MALSFSLLMAVLVLSYKSICSLGCDLPQTH-SLGNRRALILLAQMGRISPF
                        10        20        30         40        50

        60        70        80        90        100       110      
pF1KB7 ECLRENIAFELPQEFLQYTQPMKRDIKKAFYEMSLQAFNIFS-QHTFKYWKERHLKQIQI
        ::..   : .::: .. .: .: .  ....::  :.::.:: . .   :..  :.... 
NP_002 SCLKDRHDFGFPQEEFDGNQFQKAQAISVLHEMIQQTFNLFSTKDSSATWEQSLLEKFST
               60        70        80        90       100       110

        120       130       140       150       160       170      
pF1KB7 GLDQQAEYLNQCLEEDKNENEDMKEMKENEMKPSEARVPQLSSLELRRYFHRIDNFLKEK
        :.:: . :. :. .. .  :.   :. .            : : ...::.::  .: ::
NP_002 ELNQQLNDLEACVIQEVGV-EETPLMNVD------------SILAVKKYFQRITLYLTEK
              120        130                   140       150       

        180       190       200        
pF1KB7 KYSDCAWEIVRVEIRRCLYYFYKFTALFRRK 
       ::: ::::.::.:: : .     :   .::: 
NP_002 KYSPCAWEVVRAEIMRSFSLSKIFQERLRRKE
       160       170       180         

>>NP_002163 (OMIM: 147579) interferon alpha-14 precursor  (189 aa)
 initn: 285 init1: 163 opt: 163  Z-score: 180.2  bits: 40.2 E(85289): 0.0027
Smith-Waterman score: 302; 32.0% identity (60.0% similar) in 200 aa overlap (12-207:3-188)

               10        20           30        40        50       
pF1KB7 MSTKPDMIQKCLWLEILMGIFI---AGTLSLDCNLLNVHLRRVTWQNLRHLSSMSNSFPV
                  : . ..:.. .    .. :: ::: ..:    . ..:  ...:    : 
NP_002          MALPFALMMALVVLSCKSSCSLGCNLSQTH-SLNNRRTLMLMAQMRRISPF
                        10        20        30         40        50

        60        70        80        90        100       110      
pF1KB7 ECLRENIAFELPQEFLQYTQPMKRDIKKAFYEMSLQAFNIFS-QHTFKYWKERHLKQIQI
        ::..   ::.::: .. .: .: .  ....::  :.::.:: ...   : :  :... :
NP_002 SCLKDRHDFEFPQEEFDGNQFQKAQAISVLHEMMQQTFNLFSTKNSSAAWDETLLEKFYI
               60        70        80        90       100       110

        120       130       140       150       160       170      
pF1KB7 GLDQQAEYLNQCLEEDKNENEDMKEMKENEMKPSEARVPQLSSLELRRYFHRIDNFLKEK
        : :: . :. :. .. .  :.   :.:.            : : ...::.::  .: ::
NP_002 ELFQQMNDLEACVIQEVGV-EETPLMNED------------SILAVKKYFQRITLYLMEK
              120        130                   140       150       

        180       190       200        
pF1KB7 KYSDCAWEIVRVEIRRCLYYFYKFTALFRRK 
       ::: ::::.::.:: : : .  ..   .::: 
NP_002 KYSPCAWEVVRAEIMRSLSFSTNLQKRLRRKD
       160       170       180         

>>NP_002162 (OMIM: 147577) interferon alpha-10 precursor  (189 aa)
 initn: 252 init1: 163 opt: 163  Z-score: 180.2  bits: 40.2 E(85289): 0.0027
Smith-Waterman score: 283; 31.0% identity (60.0% similar) in 200 aa overlap (12-207:3-188)

               10        20           30        40        50       
pF1KB7 MSTKPDMIQKCLWLEILMGIFI---AGTLSLDCNLLNVHLRRVTWQNLRHLSSMSNSFPV
                  : . .::....    .  :: :.: ..:    . . :  :..:.   : 
NP_002          MALSFSLLMAVLVLSYKSICSLGCDLPQTH-SLGNRRALILLGQMGRISPF
                        10        20        30         40        50

        60        70        80        90        100       110      
pF1KB7 ECLRENIAFELPQEFLQYTQPMKRDIKKAFYEMSLQAFNIFS-QHTFKYWKERHLKQIQI
        ::..   :..::: .. .: .: .  ....::  :.::.:: . .   :..  :.... 
NP_002 SCLKDRHDFRIPQEEFDGNQFQKAQAISVLHEMIQQTFNLFSTEDSSAAWEQSLLEKFST
               60        70        80        90       100       110

        120       130       140       150       160       170      
pF1KB7 GLDQQAEYLNQCLEEDKNENEDMKEMKENEMKPSEARVPQLSSLELRRYFHRIDNFLKEK
        : :: . :. :. .. .  :.   :.:.            : : .:.::.::  .: :.
NP_002 ELYQQLNDLEACVIQEVGV-EETPLMNED------------SILAVRKYFQRITLYLIER
              120        130                   140       150       

        180       190       200        
pF1KB7 KYSDCAWEIVRVEIRRCLYYFYKFTALFRRK 
       ::: ::::.::.:: : : .  ..   .::: 
NP_002 KYSPCAWEVVRAEIMRSLSFSTNLQKRLRRKD
       160       170       180         

>>NP_076918 (OMIM: 147660) interferon alpha-1/13 precurs  (189 aa)
 initn: 233 init1: 158 opt: 162  Z-score: 179.2  bits: 40.0 E(85289): 0.0031
Smith-Waterman score: 267; 31.8% identity (55.9% similar) in 195 aa overlap (14-207:8-188)

               10        20        30        40        50        60
pF1KB7 MSTKPDMIQKCLWLEILMGIFIAGTLSLDCNLLNVHLRRVTWQNLRHLSSMSNSFPVECL
                    : .:. .   .. :: :.: ..:    . ..:  :..::   :  ::
NP_076       MASPFALLMVLVVLSCKSSCSLGCDLPETH-SLDNRRTLMLLAQMSRISPSSCL
                     10        20        30         40        50   

               70        80        90        100       110         
pF1KB7 RENIAFELPQEFLQYTQPMKRDIKKAFYEMSLQAFNIFS-QHTFKYWKERHLKQIQIGLD
        .   : .::: .. .: .:    ....:.  : ::.:. . .   : :  : ..   : 
NP_076 MDRHDFGFPQEEFDGNQFQKAPAISVLHELIQQIFNLFTTKDSSAAWDEDLLDKFCTELY
            60        70        80        90       100       110   

     120       130       140       150       160       170         
pF1KB7 QQAEYLNQCLEEDKNENEDMKEMKENEMKPSEARVPQLSSLELRRYFHRIDNFLKEKKYS
       :: . :. :.         :.: . .:    .:     : : ...::.::  .: :::::
NP_076 QQLNDLEACV---------MQEERVGETPLMNAD----SILAVKKYFRRITLYLTEKKYS
           120                130           140       150       160

     180       190       200        
pF1KB7 DCAWEIVRVEIRRCLYYFYKFTALFRRK 
        ::::.::.:: : :    ..   .::: 
NP_076 PCAWEVVRAEIMRSLSLSTNLQERLRRKE
              170       180         

>>NP_008831 (OMIM: 147578) interferon alpha-1/13 precurs  (190 aa)
 initn: 233 init1: 158 opt: 162  Z-score: 179.1  bits: 40.0 E(85289): 0.0031
Smith-Waterman score: 264; 31.6% identity (56.1% similar) in 196 aa overlap (16-207:8-189)

               10        20           30        40        50       
pF1KB7 MSTKPDMIQKCLWLEILMGIFI---AGTLSLDCNLLNVHLRRVTWQNLRHLSSMSNSFPV
                      .::.. .    .. :: :.: ..:    . ..:  :..::   : 
NP_008         MMASPFALLMALVVLSCKSSCSLGCDLPETHSLD-NRRTLMLLAQMSRISPS
                       10        20        30         40        50 

        60        70        80        90        100       110      
pF1KB7 ECLRENIAFELPQEFLQYTQPMKRDIKKAFYEMSLQAFNIFS-QHTFKYWKERHLKQIQI
        :: .   : .::: .. .: .:    ....:.  : ::.:. . .   : :  : ..  
NP_008 SCLMDRHDFGFPQEEFDGNQFQKAPAISVLHELIQQIFNLFTTKDSSAAWDEDLLDKFCT
              60        70        80        90       100       110 

        120       130       140       150       160       170      
pF1KB7 GLDQQAEYLNQCLEEDKNENEDMKEMKENEMKPSEARVPQLSSLELRRYFHRIDNFLKEK
        : :: . :. :.         :.: . .:    .:     : : ...::.::  .: ::
NP_008 ELYQQLNDLEACV---------MQEERVGETPLMNAD----SILAVKKYFRRITLYLTEK
             120                130           140       150        

        180       190       200        
pF1KB7 KYSDCAWEIVRVEIRRCLYYFYKFTALFRRK 
       ::: ::::.::.:: : :    ..   .::: 
NP_008 KYSPCAWEVVRAEIMRSLSLSTNLQERLRRKE
      160       170       180       190




207 residues in 1 query   sequences
60827320 residues in 85289 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Fri Nov  4 06:05:36 2016 done: Fri Nov  4 06:05:37 2016
 Total Scan time:  4.090 Total Display time: -0.030

Function used was FASTA [36.3.4 Apr, 2011]
Inquiries or Suggestions ?
Send a message to flexiclone AT kazusagt.com