Result of FASTA (omim) for pF1KB7184
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KB7184, 221 aa
  1>>>pF1KB7184 221 - 221 aa - 221 aa
Library: /omim/omim.rfq.tfa
  60827320 residues in 85289 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 5.1764+/-0.000326; mu= 14.4862+/- 0.020
 mean_var=63.6611+/-12.766, 0's: 0 Z-trim(116.1): 25  B-trim: 28 in 1/52
 Lambda= 0.160745
 statistics sampled from 27038 (27063) to 27038 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.714), E-opt: 0.2 (0.317), width:  16
 Scan time:  6.090

The best scores are:                                      opt bits E(85289)
NP_001500 (OMIM: 603435) epididymal secretory glut ( 221) 1517 360.0 1.7e-99
NP_002075 (OMIM: 138321) glutathione peroxidase 3  ( 226) 1082 259.2 4.1e-69
NP_874360 (OMIM: 607913) glutathione peroxidase 6  ( 221) 1046 250.8 1.3e-66
NP_001316719 (OMIM: 138321) glutathione peroxidase ( 235) 1022 245.2 6.6e-65
NP_000572 (OMIM: 138320,614164) glutathione peroxi ( 203)  597 146.7 2.7e-35
NP_003987 (OMIM: 603435) epididymal secretory glut ( 100)  545 134.4 6.5e-32
NP_002074 (OMIM: 138319) glutathione peroxidase 2  ( 190)  540 133.4 2.5e-31
NP_001316384 (OMIM: 138320,614164) glutathione per ( 157)  382 96.7 2.3e-20
NP_056511 (OMIM: 615784) glutathione peroxidase 7  ( 187)  283 73.8 2.1e-13
NP_001316432 (OMIM: 138320,614164) glutathione per ( 170)  237 63.1 3.2e-10
NP_001034937 (OMIM: 138322,250220) phospholipid hy ( 234)  228 61.1 1.8e-09
NP_002076 (OMIM: 138322,250220) phospholipid hydro ( 197)  226 60.6 2.1e-09
NP_001034936 (OMIM: 138322,250220) phospholipid hy ( 227)  226 60.6 2.4e-09
NP_958799 (OMIM: 138320,614164) glutathione peroxi (  98)  217 58.4   5e-09
NP_001316431 (OMIM: 138320,614164) glutathione per ( 104)  217 58.4 5.3e-09


>>NP_001500 (OMIM: 603435) epididymal secretory glutathi  (221 aa)
 initn: 1517 init1: 1517 opt: 1517  Z-score: 1907.1  bits: 360.0 E(85289): 1.7e-99
Smith-Waterman score: 1517; 100.0% identity (100.0% similar) in 221 aa overlap (1-221:1-221)

               10        20        30        40        50        60
pF1KB7 MTTQLRVVHLLPLLLACFVQTSPKQEKMKMDCHKDEKGTIYDYEAIALNKNEYVSFKQYV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MTTQLRVVHLLPLLLACFVQTSPKQEKMKMDCHKDEKGTIYDYEAIALNKNEYVSFKQYV
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB7 GKHILFVNVATYCGLTAQYPELNALQEELKPYGLVVLGFPCNQFGKQEPGDNKEILPGLK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GKHILFVNVATYCGLTAQYPELNALQEELKPYGLVVLGFPCNQFGKQEPGDNKEILPGLK
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB7 YVRPGGGFVPSFQLFEKGDVNGEKEQKVFSFLKHSCPHPSEILGTFKSISWDPVKVHDIR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 YVRPGGGFVPSFQLFEKGDVNGEKEQKVFSFLKHSCPHPSEILGTFKSISWDPVKVHDIR
              130       140       150       160       170       180

              190       200       210       220 
pF1KB7 WNFEKFLVGPDGIPVMRWSHRATVSSVKTDILAYLKQFKTK
       :::::::::::::::::::::::::::::::::::::::::
NP_001 WNFEKFLVGPDGIPVMRWSHRATVSSVKTDILAYLKQFKTK
              190       200       210       220 

>>NP_002075 (OMIM: 138321) glutathione peroxidase 3 isof  (226 aa)
 initn: 1077 init1: 1077 opt: 1082  Z-score: 1361.7  bits: 259.2 E(85289): 4.1e-69
Smith-Waterman score: 1082; 70.5% identity (87.1% similar) in 217 aa overlap (1-217:1-217)

               10        20        30        40        50        60
pF1KB7 MTTQLRVVHLLPLLLACFVQTSPKQEKMKMDCHKDEKGTIYDYEAIALNKNEYVSFKQYV
       :.  :..  :: :::: ::. :  ::: :::::   .::::.: :.... .::. ::::.
NP_002 MARLLQASCLLSLLLAGFVSQSRGQEKSKMDCHGGISGTIYEYGALTIDGEEYIPFKQYA
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB7 GKHILFVNVATYCGLTAQYPELNALQEELKPYGLVVLGFPCNQFGKQEPGDNKEILPGLK
       ::..::::::.:::::.:: ::::::::: :.:::.::::::::::::::.:.:::: ::
NP_002 GKYVLFVNVASYCGLTGQYIELNALQEELAPFGLVILGFPCNQFGKQEPGENSEILPTLK
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB7 YVRPGGGFVPSFQLFEKGDVNGEKEQKVFSFLKHSCPHPSEILGTFKSISWDPVKVHDIR
       ::::::::::.:::::::::::::::: ..:::.:::  ::.:::   . :.:.::::::
NP_002 YVRPGGGFVPNFQLFEKGDVNGEKEQKFYTFLKNSCPPTSELLGTSDRLFWEPMKVHDIR
              130       140       150       160       170       180

              190       200       210       220      
pF1KB7 WNFEKFLVGPDGIPVMRWSHRATVSSVKTDILAYLKQFKTK     
       ::::::::::::::.::: ::.:::.:: :::.:...         
NP_002 WNFEKFLVGPDGIPIMRWHHRTTVSNVKMDILSYMRRQAALGVKRK
              190       200       210       220      

>>NP_874360 (OMIM: 607913) glutathione peroxidase 6 prec  (221 aa)
 initn: 1028 init1: 1008 opt: 1046  Z-score: 1316.7  bits: 250.8 E(85289): 1.3e-66
Smith-Waterman score: 1046; 67.3% identity (88.2% similar) in 220 aa overlap (1-220:1-220)

               10        20        30        40        50        60
pF1KB7 MTTQLRVVHLLPLLLACFVQTSPKQEKMKMDCHKDEKGTIYDYEAIALNKNEYVSFKQYV
       :  :...  :. ..:. :.: . : .. :.::.:   ::::.: :..:: .::..:::..
NP_874 MFQQFQASCLVLFFLVGFAQQTLKPQNRKVDCNKGVTGTIYEYGALTLNGEEYIQFKQFA
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB7 GKHILFVNVATYCGLTAQYPELNALQEELKPYGLVVLGFPCNQFGKQEPGDNKEILPGLK
       :::.::::::.::::.:::::::::::::: .:..::.:::::::::::: :.::: :::
NP_874 GKHVLFVNVAAYCGLAAQYPELNALQEELKNFGVIVLAFPCNQFGKQEPGTNSEILLGLK
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB7 YVRPGGGFVPSFQLFEKGDVNGEKEQKVFSFLKHSCPHPSEILGTFKSISWDPVKVHDIR
       :: ::.:::::::::::::::::::::::.:::.:::  :..::. ... :.:.::::::
NP_874 YVCPGSGFVPSFQLFEKGDVNGEKEQKVFTFLKNSCPPTSDLLGSSSQLFWEPMKVHDIR
              130       140       150       160       170       180

              190       200       210       220 
pF1KB7 WNFEKFLVGPDGIPVMRWSHRATVSSVKTDILAYLKQFKTK
       ::::::::::::.:::.: :.: ::.::.::: :::::.: 
NP_874 WNFEKFLVGPDGVPVMHWFHQAPVSTVKSDILEYLKQFNTH
              190       200       210       220 

>>NP_001316719 (OMIM: 138321) glutathione peroxidase 3 i  (235 aa)
 initn: 1063 init1: 1016 opt: 1022  Z-score: 1286.3  bits: 245.2 E(85289): 6.6e-65
Smith-Waterman score: 1054; 67.7% identity (83.6% similar) in 226 aa overlap (1-217:1-226)

               10        20                 30        40        50 
pF1KB7 MTTQLRVVHLLPLLLACFVQTSPKQEKMK---------MDCHKDEKGTIYDYEAIALNKN
       :.  :..  :: :::: ::. :  ::: :         ::::   .::::.: :.... .
NP_001 MARLLQASCLLSLLLAGFVSQSRGQEKSKAPRQMGNPQMDCHGGISGTIYEYGALTIDGE
               10        20        30        40        50        60

              60        70        80        90       100       110 
pF1KB7 EYVSFKQYVGKHILFVNVATYCGLTAQYPELNALQEELKPYGLVVLGFPCNQFGKQEPGD
       ::. ::::.::..::::::.:::::.:: ::::::::: :.:::.::::::::::::::.
NP_001 EYIPFKQYAGKYVLFVNVASYCGLTGQYIELNALQEELAPFGLVILGFPCNQFGKQEPGE
               70        80        90       100       110       120

             120       130       140       150       160       170 
pF1KB7 NKEILPGLKYVRPGGGFVPSFQLFEKGDVNGEKEQKVFSFLKHSCPHPSEILGTFKSISW
       :.:::: ::::::::::::.:::::::::::::::: ..:::.:::  ::.:::   . :
NP_001 NSEILPTLKYVRPGGGFVPNFQLFEKGDVNGEKEQKFYTFLKNSCPPTSELLGTSDRLFW
              130       140       150       160       170       180

             180       190       200       210       220      
pF1KB7 DPVKVHDIRWNFEKFLVGPDGIPVMRWSHRATVSSVKTDILAYLKQFKTK     
       .:.::::::::::::::::::::.::: ::.:::.:: :::.:...         
NP_001 EPMKVHDIRWNFEKFLVGPDGIPIMRWHHRTTVSNVKMDILSYMRRQAALGVKRK
              190       200       210       220       230     

>>NP_000572 (OMIM: 138320,614164) glutathione peroxidase  (203 aa)
 initn: 561 init1: 350 opt: 597  Z-score: 754.6  bits: 146.7 E(85289): 2.7e-35
Smith-Waterman score: 597; 50.0% identity (73.9% similar) in 184 aa overlap (39-217:15-198)

       10        20        30        40        50        60        
pF1KB7 HLLPLLLACFVQTSPKQEKMKMDCHKDEKGTIYDYEAIALNKNEYVSFKQYVGKHILFVN
                                     ..: . :  :  .: ::. .  :: .:. :
NP_000                 MCAARLAAAAAAAQSVYAFSARPLAGGEPVSLGSLRGKVLLIEN
                               10        20        30        40    

       70         80        90       100       110       120       
pF1KB7 VATYCGLTAQ-YPELNALQEELKPYGLVVLGFPCNQFGKQEPGDNKEILPGLKYVRPGGG
       ::. :: :.. : ..: ::..: : :::::::::::::.:: . :.::: .:::::::::
NP_000 VASLCGTTVRDYTQMNELQRRLGPRGLVVLGFPCNQFGHQENAKNEEILNSLKYVRPGGG
           50        60        70        80        90       100    

       130       140       150       160           170       180   
pF1KB7 FVPSFQLFEKGDVNGEKEQKVFSFLKHSCPHPSE----ILGTFKSISWDPVKVHDIRWNF
       : :.:.:::: .:::   . .:.::... : ::.    ..   : :.:.::  .:. :::
NP_000 FEPNFMLFEKCEVNGAGAHPLFAFLREALPAPSDDATALMTDPKLITWSPVCRNDVAWNF
          110       120       130       140       150       160    

           190       200       210       220  
pF1KB7 EKFLVGPDGIPVMRWSHRATVSSVKTDILAYLKQFKTK 
       :::::::::.:. :.:.:  . ... :: : :.:     
NP_000 EKFLVGPDGVPLRRYSRRFQTIDIEPDIEALLSQGPSCA
          170       180       190       200   

>>NP_003987 (OMIM: 603435) epididymal secretory glutathi  (100 aa)
 initn: 560 init1: 545 opt: 545  Z-score: 694.0  bits: 134.4 E(85289): 6.5e-32
Smith-Waterman score: 545; 92.1% identity (96.6% similar) in 89 aa overlap (1-89:1-89)

               10        20        30        40        50        60
pF1KB7 MTTQLRVVHLLPLLLACFVQTSPKQEKMKMDCHKDEKGTIYDYEAIALNKNEYVSFKQYV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 MTTQLRVVHLLPLLLACFVQTSPKQEKMKMDCHKDEKGTIYDYEAIALNKNEYVSFKQYV
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB7 GKHILFVNVATYCGLTAQYPELNALQEELKPYGLVVLGFPCNQFGKQEPGDNKEILPGLK
       :::::::::::::::::::: ...  :.:                               
NP_003 GKHILFVNVATYCGLTAQYPGMSVQGEDLYLVSSFLRKGM                    
               70        80        90       100                    

>>NP_002074 (OMIM: 138319) glutathione peroxidase 2 [Hom  (190 aa)
 initn: 482 init1: 313 opt: 540  Z-score: 683.5  bits: 133.4 E(85289): 2.5e-31
Smith-Waterman score: 540; 46.4% identity (72.1% similar) in 183 aa overlap (39-216:7-187)

       10        20        30        40        50        60        
pF1KB7 HLLPLLLACFVQTSPKQEKMKMDCHKDEKGTIYDYEAIALNKNEYVSFKQYVGKHILFVN
                                     ..::  ::.:. .: :.:. . :. .:. :
NP_002                         MAFIAKSFYDLSAISLD-GEKVDFNTFRGRAVLIEN
                                       10         20        30     

       70         80        90       100       110       120       
pF1KB7 VATYCGLTAQ-YPELNALQEELKPYGLVVLGFPCNQFGKQEPGDNKEILPGLKYVRPGGG
       ::. :: :.. . .:: :: .. :  ::::::::::::.::  .:.::: .:::::::::
NP_002 VASLCGTTTRDFTQLNELQCRF-PRRLVVLGFPCNQFGHQENCQNEEILNSLKYVRPGGG
          40        50         60        70        80        90    

       130       140       150       160           170       180   
pF1KB7 FVPSFQLFEKGDVNGEKEQKVFSFLKHSCPHPSE----ILGTFKSISWDPVKVHDIRWNF
       . :.: : .: .:::..:. ::..:: . :.: .    ..   : : :.::.  :. :::
NP_002 YQPTFTLVQKCEVNGQNEHPVFAYLKDKLPYPYDDPFSLMTDPKLIIWSPVRRSDVAWNF
          100       110       120       130       140       150    

           190       200       210       220 
pF1KB7 EKFLVGPDGIPVMRWSHRATVSSVKTDILAYLKQFKTK
       ::::.::.: :  :.:.   . ... ::   ::     
NP_002 EKFLIGPEGEPFRRYSRTFPTINIEPDIKRLLKVAI  
          160       170       180       190  

>>NP_001316384 (OMIM: 138320,614164) glutathione peroxid  (157 aa)
 initn: 363 init1: 206 opt: 382  Z-score: 486.8  bits: 96.7 E(85289): 2.3e-20
Smith-Waterman score: 382; 49.6% identity (74.8% similar) in 115 aa overlap (107-217:38-152)

         80        90       100       110       120       130      
pF1KB7 AQYPELNALQEELKPYGLVVLGFPCNQFGKQEPGDNKEILPGLKYVRPGGGFVPSFQLFE
                                     .: . :.::: .:::::::::: :.:.:::
NP_001 AAAAAAQSVYAFSARPLAGGEPVSLGSLRGKENAKNEEILNSLKYVRPGGGFEPNFMLFE
        10        20        30        40        50        60       

        140       150       160           170       180       190  
pF1KB7 KGDVNGEKEQKVFSFLKHSCPHPSE----ILGTFKSISWDPVKVHDIRWNFEKFLVGPDG
       : .:::   . .:.::... : ::.    ..   : :.:.::  .:. ::::::::::::
NP_001 KCEVNGAGAHPLFAFLREALPAPSDDATALMTDPKLITWSPVCRNDVAWNFEKFLVGPDG
        70        80        90       100       110       120       

            200       210       220  
pF1KB7 IPVMRWSHRATVSSVKTDILAYLKQFKTK 
       .:. :.:.:  . ... :: : :.:     
NP_001 VPLRRYSRRFQTIDIEPDIEALLSQGPSCA
       130       140       150       

>>NP_056511 (OMIM: 615784) glutathione peroxidase 7 prec  (187 aa)
 initn: 212 init1: 153 opt: 283  Z-score: 361.5  bits: 73.8 E(85289): 2.1e-13
Smith-Waterman score: 327; 34.6% identity (61.7% similar) in 188 aa overlap (32-218:18-179)

              10        20        30        40        50        60 
pF1KB7 TTQLRVVHLLPLLLACFVQTSPKQEKMKMDCHKDEKGTIYDYEAIALNKNEYVSFKQYVG
                                     : ..:.  .::..:. . ... ::...: :
NP_056              MVAATVAAAWLLLWAAACAQQEQD-FYDFKAVNI-RGKLVSLEKYRG
                            10        20         30         40     

              70         80        90       100       110       120
pF1KB7 KHILFVNVATYCGLTAQ-YPELNALQEELKPYGLVVLGFPCNQFGKQEPGDNKEILPGLK
       .  : ::::. ::.: : :  :. ::..: :. . ::.:::::::.::: .::::    .
NP_056 SVSLVVNVASECGFTDQHYRALQQLQRDLGPHHFNVLAFPCNQFGQQEPDSNKEI---ES
          50        60        70        80        90       100     

              130       140       150       160       170       180
pF1KB7 YVRPGGGFVPSFQLFEKGDVNGEKEQKVFSFLKHSCPHPSEILGTFKSISWDPVKVHDIR
       ..:    .  :: .: :  :.:   . .:..: ..  .             .:.      
NP_056 FARR--TYSVSFPMFSKIAVTGTGAHPAFKYLAQTSGK-------------EPT------
              110       120       130                    140       

              190       200       210       220      
pF1KB7 WNFEKFLVGPDGIPVMRWSHRATVSSVKTDILAYLKQFKTK     
       ::: :.::.:::  :  :.  ..:  :. .: : ....        
NP_056 WNFWKYLVAPDGKVVGAWDPTVSVEEVRPQITALVRKLILLKREDL
             150       160       170       180       

>>NP_001316432 (OMIM: 138320,614164) glutathione peroxid  (170 aa)
 initn: 184 init1: 135 opt: 237  Z-score: 304.5  bits: 63.1 E(85289): 3.2e-10
Smith-Waterman score: 237; 42.0% identity (64.3% similar) in 112 aa overlap (39-144:15-125)

       10        20        30        40        50        60        
pF1KB7 HLLPLLLACFVQTSPKQEKMKMDCHKDEKGTIYDYEAIALNKNEYVSFKQYVGKHILFVN
                                     ..: . :  :  .: ::. .  :: .:. :
NP_001                 MCAARLAAAAAAAQSVYAFSARPLAGGEPVSLGSLRGKVLLIEN
                               10        20        30        40    

       70         80        90       100           110        120  
pF1KB7 VATYCGLTAQ-YPELNALQEELKPYGLVVLGFPCNQFGKQEP----GDNKEILPG-LKYV
       ::. :: :.. : ..: ::..: : :::::::::::::.: :    :. .:   . .  :
NP_001 VASLCGTTVRDYTQMNELQRRLGPRGLVVLGFPCNQFGHQLPFSPVGERQERRDSEFPQV
           50        60        70        80        90       100    

            130       140       150       160       170       180  
pF1KB7 RPGGGFVPSFQLFEKGDVNGEKEQKVFSFLKHSCPHPSEILGTFKSISWDPVKVHDIRWN
       ::.  .: . ::    .: ::.                                      
NP_001 RPAWWWVRA-QLHALREVRGERCGGAPSLRLPAGGPASSQRRRHRAYDRPQAHHLVSGVS
          110        120       130       140       150       160   




221 residues in 1 query   sequences
60827320 residues in 85289 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Fri Nov  4 05:40:30 2016 done: Fri Nov  4 05:40:31 2016
 Total Scan time:  6.090 Total Display time: -0.010

Function used was FASTA [36.3.4 Apr, 2011]
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