Result of FASTA (omim) for pF1KB7169
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KB7169, 433 aa
  1>>>pF1KB7169 433 - 433 aa - 433 aa
Library: /omim/omim.rfq.tfa
  60827320 residues in 85289 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 7.7772+/-0.000364; mu= 6.1555+/- 0.023
 mean_var=145.5854+/-29.009, 0's: 0 Z-trim(117.8): 48  B-trim: 306 in 1/52
 Lambda= 0.106296
 statistics sampled from 30110 (30160) to 30110 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.711), E-opt: 0.2 (0.354), width:  16
 Scan time: 10.120

The best scores are:                                      opt bits E(85289)
XP_011507718 (OMIM: 116200,600897,612474) PREDICTE ( 433) 2876 452.7 8.4e-127
NP_005258 (OMIM: 116200,600897,612474) gap junctio ( 433) 2876 452.7 8.4e-127
XP_011507719 (OMIM: 116200,600897,612474) PREDICTE ( 427) 2840 447.2 3.8e-125
XP_011533350 (OMIM: 121015,601885) PREDICTED: gap  ( 435) 1175 191.9 2.8e-48
NP_068773 (OMIM: 121015,601885) gap junction alpha ( 435) 1175 191.9 2.8e-48
XP_016856533 (OMIM: 108770,121013,612474,614049) P ( 358) 1032 169.9 9.6e-42
NP_005257 (OMIM: 108770,121013,612474,614049) gap  ( 358) 1032 169.9 9.6e-42
XP_005273008 (OMIM: 108770,121013,612474,614049) P ( 358) 1032 169.9 9.6e-42
NP_859054 (OMIM: 108770,121013,612474,614049) gap  ( 358) 1032 169.9 9.6e-42
NP_115991 (OMIM: 611924) gap junction alpha-10 pro ( 543)  955 158.2 4.9e-38
NP_110399 (OMIM: 611923) gap junction alpha-9 prot ( 515)  945 156.6 1.3e-37
NP_000156 (OMIM: 104100,121014,133200,164200,18610 ( 382)  900 149.7 1.3e-35
XP_016856532 (OMIM: 121012) PREDICTED: gap junctio ( 333)  881 146.7 8.5e-35
NP_002051 (OMIM: 121012) gap junction alpha-4 prot ( 333)  881 146.7 8.5e-35
XP_005270807 (OMIM: 121012) PREDICTED: gap junctio ( 333)  881 146.7 8.5e-35
NP_003995 (OMIM: 121011,124500,148210,148350,14920 ( 226)  501 88.3 2.1e-17
XP_011533351 (OMIM: 121011,124500,148210,148350,14 ( 226)  501 88.3 2.1e-17
NP_699199 (OMIM: 611922) gap junction delta-4 prot ( 370)  495 87.5 6.1e-17
NP_001103689 (OMIM: 129500,220290,304400,604418,61 ( 261)  488 86.4 9.6e-17
XP_016875846 (OMIM: 129500,220290,304400,604418,61 ( 261)  488 86.4 9.6e-17
XP_016875848 (OMIM: 129500,220290,304400,604418,61 ( 261)  488 86.4 9.6e-17
NP_006774 (OMIM: 129500,220290,304400,604418,61264 ( 261)  488 86.4 9.6e-17
XP_016875847 (OMIM: 129500,220290,304400,604418,61 ( 261)  488 86.4 9.6e-17
XP_016875849 (OMIM: 129500,220290,304400,604418,61 ( 261)  488 86.4 9.6e-17
NP_001103691 (OMIM: 129500,220290,304400,604418,61 ( 261)  488 86.4 9.6e-17
NP_001103690 (OMIM: 129500,220290,304400,604418,61 ( 261)  488 86.4 9.6e-17
NP_001091111 (OMIM: 302800,304040) gap junction be ( 283)  464 82.7 1.3e-15
XP_011529209 (OMIM: 302800,304040) PREDICTED: gap  ( 283)  464 82.7 1.3e-15
XP_016884897 (OMIM: 302800,304040) PREDICTED: gap  ( 283)  464 82.7 1.3e-15
NP_000157 (OMIM: 302800,304040) gap junction beta- ( 283)  464 82.7 1.3e-15
NP_076872 (OMIM: 133200,220290,603324,612644) gap  ( 270)  463 82.5 1.4e-15
NP_001005752 (OMIM: 133200,220290,603324,612644) g ( 270)  463 82.5 1.4e-15
NP_694944 (OMIM: 133200,605425) gap junction beta- ( 266)  462 82.4 1.5e-15
XP_011538981 (OMIM: 133200,605425) PREDICTED: gap  ( 266)  462 82.4 1.5e-15
XP_005256978 (OMIM: 608655) PREDICTED: gap junctio ( 396)  464 82.8 1.7e-15
NP_005488 (OMIM: 608655) gap junction gamma-1 prot ( 396)  464 82.8 1.7e-15
XP_005256977 (OMIM: 608655) PREDICTED: gap junctio ( 396)  464 82.8 1.7e-15
NP_001073852 (OMIM: 608655) gap junction gamma-1 p ( 396)  464 82.8 1.7e-15
NP_065168 (OMIM: 608803,608804,613206,613480) gap  ( 439)  452 81.0 6.8e-15
XP_005270808 (OMIM: 604493) PREDICTED: gap junctio ( 273)  442 79.3 1.3e-14
NP_005259 (OMIM: 604493) gap junction beta-5 prote ( 273)  442 79.3 1.3e-14
NP_065711 (OMIM: 607058) gap junction delta-2 prot ( 321)  433 78.0 3.9e-14
NP_940970 (OMIM: 611921) gap junction beta-7 prote ( 223)  425 76.7 6.8e-14
XP_005248773 (OMIM: 611921) PREDICTED: gap junctio ( 223)  425 76.7 6.8e-14
NP_689343 (OMIM: 607425) gap junction delta-3 prot ( 294)  399 72.8 1.4e-12
XP_016877927 (OMIM: 607058) PREDICTED: gap junctio ( 270)  368 68.0 3.4e-11
NP_853516 (OMIM: 611925) gap junction gamma-3 prot ( 279)  355 66.0 1.4e-10


>>XP_011507718 (OMIM: 116200,600897,612474) PREDICTED: g  (433 aa)
 initn: 2876 init1: 2876 opt: 2876  Z-score: 2397.5  bits: 452.7 E(85289): 8.4e-127
Smith-Waterman score: 2876; 100.0% identity (100.0% similar) in 433 aa overlap (1-433:1-433)

               10        20        30        40        50        60
pF1KB7 MGDWSFLGNILEEVNEHSTVIGRVWLTVLFIFRILILGTAAEFVWGDEQSDFVCNTQQPG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MGDWSFLGNILEEVNEHSTVIGRVWLTVLFIFRILILGTAAEFVWGDEQSDFVCNTQQPG
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB7 CENVCYDEAFPISHIRLWVLQIIFVSTPSLMYVGHAVHYVRMEEKRKSREAEELGQQAGT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 CENVCYDEAFPISHIRLWVLQIIFVSTPSLMYVGHAVHYVRMEEKRKSREAEELGQQAGT
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB7 NGGPDQGSVKKSSGSKGTKKFRLEGTLLRTYICHIIFKTLFEVGFIVGHYFLYGFRILPL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NGGPDQGSVKKSSGSKGTKKFRLEGTLLRTYICHIIFKTLFEVGFIVGHYFLYGFRILPL
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB7 YRCSRWPCPNVVDCFVSRPTEKTIFILFMLSVASVSLFLNVMELGHLGLKGIRSALKRPV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 YRCSRWPCPNVVDCFVSRPTEKTIFILFMLSVASVSLFLNVMELGHLGLKGIRSALKRPV
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB7 EQPLGEIPEKSLHSIAVSSIQKAKGYQLLEEEKIVSHYFPLTEVGMVETSPLPAKPFNQF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EQPLGEIPEKSLHSIAVSSIQKAKGYQLLEEEKIVSHYFPLTEVGMVETSPLPAKPFNQF
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KB7 EEKISTGPLGDLSRGYQETLPSYAQVGAQEVEGEGPPAEEGAEPEVGEKKEEAERLTTEE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EEKISTGPLGDLSRGYQETLPSYAQVGAQEVEGEGPPAEEGAEPEVGEKKEEAERLTTEE
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KB7 QEKVAVPEGEKVETPGVDKEGEKEEPQSEKVSKQGLPAEKTPSLCPELTTDDARPLSRLS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QEKVAVPEGEKVETPGVDKEGEKEEPQSEKVSKQGLPAEKTPSLCPELTTDDARPLSRLS
              370       380       390       400       410       420

              430   
pF1KB7 KASSRARSDDLTV
       :::::::::::::
XP_011 KASSRARSDDLTV
              430   

>>NP_005258 (OMIM: 116200,600897,612474) gap junction al  (433 aa)
 initn: 2876 init1: 2876 opt: 2876  Z-score: 2397.5  bits: 452.7 E(85289): 8.4e-127
Smith-Waterman score: 2876; 100.0% identity (100.0% similar) in 433 aa overlap (1-433:1-433)

               10        20        30        40        50        60
pF1KB7 MGDWSFLGNILEEVNEHSTVIGRVWLTVLFIFRILILGTAAEFVWGDEQSDFVCNTQQPG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 MGDWSFLGNILEEVNEHSTVIGRVWLTVLFIFRILILGTAAEFVWGDEQSDFVCNTQQPG
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB7 CENVCYDEAFPISHIRLWVLQIIFVSTPSLMYVGHAVHYVRMEEKRKSREAEELGQQAGT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 CENVCYDEAFPISHIRLWVLQIIFVSTPSLMYVGHAVHYVRMEEKRKSREAEELGQQAGT
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB7 NGGPDQGSVKKSSGSKGTKKFRLEGTLLRTYICHIIFKTLFEVGFIVGHYFLYGFRILPL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 NGGPDQGSVKKSSGSKGTKKFRLEGTLLRTYICHIIFKTLFEVGFIVGHYFLYGFRILPL
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB7 YRCSRWPCPNVVDCFVSRPTEKTIFILFMLSVASVSLFLNVMELGHLGLKGIRSALKRPV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 YRCSRWPCPNVVDCFVSRPTEKTIFILFMLSVASVSLFLNVMELGHLGLKGIRSALKRPV
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB7 EQPLGEIPEKSLHSIAVSSIQKAKGYQLLEEEKIVSHYFPLTEVGMVETSPLPAKPFNQF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 EQPLGEIPEKSLHSIAVSSIQKAKGYQLLEEEKIVSHYFPLTEVGMVETSPLPAKPFNQF
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KB7 EEKISTGPLGDLSRGYQETLPSYAQVGAQEVEGEGPPAEEGAEPEVGEKKEEAERLTTEE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 EEKISTGPLGDLSRGYQETLPSYAQVGAQEVEGEGPPAEEGAEPEVGEKKEEAERLTTEE
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KB7 QEKVAVPEGEKVETPGVDKEGEKEEPQSEKVSKQGLPAEKTPSLCPELTTDDARPLSRLS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 QEKVAVPEGEKVETPGVDKEGEKEEPQSEKVSKQGLPAEKTPSLCPELTTDDARPLSRLS
              370       380       390       400       410       420

              430   
pF1KB7 KASSRARSDDLTV
       :::::::::::::
NP_005 KASSRARSDDLTV
              430   

>>XP_011507719 (OMIM: 116200,600897,612474) PREDICTED: g  (427 aa)
 initn: 2840 init1: 2840 opt: 2840  Z-score: 2367.7  bits: 447.2 E(85289): 3.8e-125
Smith-Waterman score: 2840; 100.0% identity (100.0% similar) in 427 aa overlap (1-427:1-427)

               10        20        30        40        50        60
pF1KB7 MGDWSFLGNILEEVNEHSTVIGRVWLTVLFIFRILILGTAAEFVWGDEQSDFVCNTQQPG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MGDWSFLGNILEEVNEHSTVIGRVWLTVLFIFRILILGTAAEFVWGDEQSDFVCNTQQPG
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB7 CENVCYDEAFPISHIRLWVLQIIFVSTPSLMYVGHAVHYVRMEEKRKSREAEELGQQAGT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 CENVCYDEAFPISHIRLWVLQIIFVSTPSLMYVGHAVHYVRMEEKRKSREAEELGQQAGT
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB7 NGGPDQGSVKKSSGSKGTKKFRLEGTLLRTYICHIIFKTLFEVGFIVGHYFLYGFRILPL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NGGPDQGSVKKSSGSKGTKKFRLEGTLLRTYICHIIFKTLFEVGFIVGHYFLYGFRILPL
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB7 YRCSRWPCPNVVDCFVSRPTEKTIFILFMLSVASVSLFLNVMELGHLGLKGIRSALKRPV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 YRCSRWPCPNVVDCFVSRPTEKTIFILFMLSVASVSLFLNVMELGHLGLKGIRSALKRPV
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB7 EQPLGEIPEKSLHSIAVSSIQKAKGYQLLEEEKIVSHYFPLTEVGMVETSPLPAKPFNQF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EQPLGEIPEKSLHSIAVSSIQKAKGYQLLEEEKIVSHYFPLTEVGMVETSPLPAKPFNQF
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KB7 EEKISTGPLGDLSRGYQETLPSYAQVGAQEVEGEGPPAEEGAEPEVGEKKEEAERLTTEE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EEKISTGPLGDLSRGYQETLPSYAQVGAQEVEGEGPPAEEGAEPEVGEKKEEAERLTTEE
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KB7 QEKVAVPEGEKVETPGVDKEGEKEEPQSEKVSKQGLPAEKTPSLCPELTTDDARPLSRLS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QEKVAVPEGEKVETPGVDKEGEKEEPQSEKVSKQGLPAEKTPSLCPELTTDDARPLSRLS
              370       380       390       400       410       420

              430   
pF1KB7 KASSRARSDDLTV
       :::::::      
XP_011 KASSRAR      
                    

>>XP_011533350 (OMIM: 121015,601885) PREDICTED: gap junc  (435 aa)
 initn: 1171 init1: 657 opt: 1175  Z-score: 987.7  bits: 191.9 E(85289): 2.8e-48
Smith-Waterman score: 1175; 45.6% identity (66.2% similar) in 447 aa overlap (1-433:1-435)

               10        20        30        40        50        60
pF1KB7 MGDWSFLGNILEEVNEHSTVIGRVWLTVLFIFRILILGTAAEFVWGDEQSDFVCNTQQPG
       :::::::: .::...:::::::.::::::::::::.::.::: :::::::::.:::::::
XP_011 MGDWSFLGRLLENAQEHSTVIGKVWLTVLFIFRILVLGAAAEDVWGDEQSDFTCNTQQPG
               10        20        30        40        50        60

               70        80        90       100       110          
pF1KB7 CENVCYDEAFPISHIRLWVLQIIFVSTPSLMYVGHAVHYVRMEEKRKSREAEE-LGQQAG
       :::::::.::::::::.:.:::::::::.:.:.::..: ::::::.: :: :: : ... 
XP_011 CENVCYDRAFPISHIRFWALQIIFVSTPTLIYLGHVLHIVRMEEKKKEREEEEQLKRESP
               70        80        90       100       110       120

     120       130       140       150       160       170         
pF1KB7 TNGGPDQGSVKKSSGSKGTKKFRLEGTLLRTYICHIIFKTLFEVGFIVGHYFLYGFRILP
       .   : : .  .:  ..:  . :. :.:::::. .::::::::::::.:.::::::.. :
XP_011 SPKEPPQDN-PSSRDDRG--RVRMAGALLRTYVFNIIFKTLFEVGFIAGQYFLYGFELKP
               130         140       150       160       170       

     180       190       200       210       220       230         
pF1KB7 LYRCSRWPCPNVVDCFVSRPTEKTIFILFMLSVASVSLFLNVMELGHLGLKGIRSALKRP
       ::::.::::::.::::.::::::::::.:::.:: .::.::..:. ::: : .....   
XP_011 LYRCDRWPCPNTVDCFISRPTEKTIFIIFMLAVACASLLLNMLEIYHLGWKKLKQGVTSR
       180       190       200       210       220       230       

     240       250       260       270       280         290       
pF1KB7 VEQPLGEIPEKSLHSIAVSSIQKAKGYQLLEEEKIVSHYFPLTEVGMV--ETSPLPAKPF
       .    .: :  .     .   ..  .  .      .    :: ..  :    .: ::  :
XP_011 LGPDASEAPLGTADPPPLPPSSRPPAVAIGFPPYYAHTAAPLGQARAVGYPGAPPPAADF
       240       250       260       270       280       290       

         300       310       320       330       340       350     
pF1KB7 N--QFEEKISTGPLGDLSRGYQETLPSYAQVGAQEVEGEGPPAEEGAEPEVGEKKEEAER
       .   . :  . :  . :  :... : .  . . : .: . ::: . : : ..     .  
XP_011 KLLALTEARGKGQSAKLYNGHHHLLMTEQNWANQAAERQ-PPALK-AYPAASTPAAPSPV
       300       310       320       330        340        350     

              360          370       380       390       400       
pF1KB7 LTT-----EEQEKVAVP---EGEKVETPGVDKEGEKEEPQSEKVSKQGLPAEKTPSLCPE
        ..     .: :  :.:   .:      :    :  :: ..  ..   .         : 
XP_011 GSSSPPLAHEAEAGAAPLLLDGSGSSLEGSALAGTPEEEEQAVTTAAQMHQ-------PP
         360       370       380       390       400               

       410       420        430   
pF1KB7 LTTDDARPLSRLSKASS-RARSDDLTV
       :   :    :. :.::: ::: .::..
XP_011 LPLGDPGRASKASRASSGRARPEDLAI
      410       420       430     

>>NP_068773 (OMIM: 121015,601885) gap junction alpha-3 p  (435 aa)
 initn: 1171 init1: 657 opt: 1175  Z-score: 987.7  bits: 191.9 E(85289): 2.8e-48
Smith-Waterman score: 1175; 45.6% identity (66.2% similar) in 447 aa overlap (1-433:1-435)

               10        20        30        40        50        60
pF1KB7 MGDWSFLGNILEEVNEHSTVIGRVWLTVLFIFRILILGTAAEFVWGDEQSDFVCNTQQPG
       :::::::: .::...:::::::.::::::::::::.::.::: :::::::::.:::::::
NP_068 MGDWSFLGRLLENAQEHSTVIGKVWLTVLFIFRILVLGAAAEDVWGDEQSDFTCNTQQPG
               10        20        30        40        50        60

               70        80        90       100       110          
pF1KB7 CENVCYDEAFPISHIRLWVLQIIFVSTPSLMYVGHAVHYVRMEEKRKSREAEE-LGQQAG
       :::::::.::::::::.:.:::::::::.:.:.::..: ::::::.: :: :: : ... 
NP_068 CENVCYDRAFPISHIRFWALQIIFVSTPTLIYLGHVLHIVRMEEKKKEREEEEQLKRESP
               70        80        90       100       110       120

     120       130       140       150       160       170         
pF1KB7 TNGGPDQGSVKKSSGSKGTKKFRLEGTLLRTYICHIIFKTLFEVGFIVGHYFLYGFRILP
       .   : : .  .:  ..:  . :. :.:::::. .::::::::::::.:.::::::.. :
NP_068 SPKEPPQDN-PSSRDDRG--RVRMAGALLRTYVFNIIFKTLFEVGFIAGQYFLYGFELKP
               130         140       150       160       170       

     180       190       200       210       220       230         
pF1KB7 LYRCSRWPCPNVVDCFVSRPTEKTIFILFMLSVASVSLFLNVMELGHLGLKGIRSALKRP
       ::::.::::::.::::.::::::::::.:::.:: .::.::..:. ::: : .....   
NP_068 LYRCDRWPCPNTVDCFISRPTEKTIFIIFMLAVACASLLLNMLEIYHLGWKKLKQGVTSR
       180       190       200       210       220       230       

     240       250       260       270       280         290       
pF1KB7 VEQPLGEIPEKSLHSIAVSSIQKAKGYQLLEEEKIVSHYFPLTEVGMV--ETSPLPAKPF
       .    .: :  .     .   ..  .  .      .    :: ..  :    .: ::  :
NP_068 LGPDASEAPLGTADPPPLPPSSRPPAVAIGFPPYYAHTAAPLGQARAVGYPGAPPPAADF
       240       250       260       270       280       290       

         300       310       320       330       340       350     
pF1KB7 N--QFEEKISTGPLGDLSRGYQETLPSYAQVGAQEVEGEGPPAEEGAEPEVGEKKEEAER
       .   . :  . :  . :  :... : .  . . : .: . ::: . : : ..     .  
NP_068 KLLALTEARGKGQSAKLYNGHHHLLMTEQNWANQAAERQ-PPALK-AYPAASTPAAPSPV
       300       310       320       330        340        350     

              360          370       380       390       400       
pF1KB7 LTT-----EEQEKVAVP---EGEKVETPGVDKEGEKEEPQSEKVSKQGLPAEKTPSLCPE
        ..     .: :  :.:   .:      :    :  :: ..  ..   .         : 
NP_068 GSSSPPLAHEAEAGAAPLLLDGSGSSLEGSALAGTPEEEEQAVTTAAQMHQ-------PP
         360       370       380       390       400               

       410       420        430   
pF1KB7 LTTDDARPLSRLSKASS-RARSDDLTV
       :   :    :. :.::: ::: .::..
NP_068 LPLGDPGRASKASRASSGRARPEDLAI
      410       420       430     

>>XP_016856533 (OMIM: 108770,121013,612474,614049) PREDI  (358 aa)
 initn: 1104 init1: 649 opt: 1032  Z-score: 870.4  bits: 169.9 E(85289): 9.6e-42
Smith-Waterman score: 1032; 61.8% identity (83.8% similar) in 241 aa overlap (1-239:1-241)

               10        20        30        40        50        60
pF1KB7 MGDWSFLGNILEEVNEHSTVIGRVWLTVLFIFRILILGTAAEFVWGDEQSDFVCNTQQPG
       :::::::::.::::..::::.:.::::::::::.:.::::::  :::::.:: :.: :::
XP_016 MGDWSFLGNFLEEVHKHSTVVGKVWLTVLFIFRMLVLGTAAESSWGDEQADFRCDTIQPG
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB7 CENVCYDEAFPISHIRLWVLQIIFVSTPSLMYVGHAVHYVRMEEKRKSREAEELGQQAGT
       :.:::::.:::::::: :::::::::::::.:.:::.: :::.:::: ::::.  .  :.
XP_016 CQNVCYDQAFPISHIRYWVLQIIFVSTPSLVYMGHAMHTVRMQEKRKLREAERAKEVRGS
               70        80        90       100       110       120

                130       140       150       160       170        
pF1KB7 NGG--PDQGSVKKSSGSKGTKKFRLEGTLLRTYICHIIFKTLFEVGFIVGHYFLYGFRIL
       ..   :   ... :   .:. .. :.:::: ::.: :...: .:::::::.::.::. . 
XP_016 GSYEYPVAEKAELSCWEEGNGRIALQGTLLNTYVCSILIRTTMEVGFIVGQYFIYGIFLT
              130       140       150       160       170       180

      180       190       200       210       220       230        
pF1KB7 PLYRCSRWPCPNVVDCFVSRPTEKTIFILFMLSVASVSLFLNVMELGHLGLKGIRSALKR
        :. : : :::. :.:.:::::::..::.:::.::..::.:.. :: ::: : ::. . .
XP_016 TLHVCRRSPCPHPVNCYVSRPTEKNVFIVFMLAVAALSLLLSLAELYHLGWKKIRQRFVK
              190       200       210       220       230       240

      240       250       260       270       280       290        
pF1KB7 PVEQPLGEIPEKSLHSIAVSSIQKAKGYQLLEEEKIVSHYFPLTEVGMVETSPLPAKPFN
       :                                                           
XP_016 PRQHMAKCQLSGPSVGIVQSCTPPPDFNQCLENGPGGKFFNPFSNNMASQQNTDNLVTEQ
              250       260       270       280       290       300

>>NP_005257 (OMIM: 108770,121013,612474,614049) gap junc  (358 aa)
 initn: 1104 init1: 649 opt: 1032  Z-score: 870.4  bits: 169.9 E(85289): 9.6e-42
Smith-Waterman score: 1032; 61.8% identity (83.8% similar) in 241 aa overlap (1-239:1-241)

               10        20        30        40        50        60
pF1KB7 MGDWSFLGNILEEVNEHSTVIGRVWLTVLFIFRILILGTAAEFVWGDEQSDFVCNTQQPG
       :::::::::.::::..::::.:.::::::::::.:.::::::  :::::.:: :.: :::
NP_005 MGDWSFLGNFLEEVHKHSTVVGKVWLTVLFIFRMLVLGTAAESSWGDEQADFRCDTIQPG
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB7 CENVCYDEAFPISHIRLWVLQIIFVSTPSLMYVGHAVHYVRMEEKRKSREAEELGQQAGT
       :.:::::.:::::::: :::::::::::::.:.:::.: :::.:::: ::::.  .  :.
NP_005 CQNVCYDQAFPISHIRYWVLQIIFVSTPSLVYMGHAMHTVRMQEKRKLREAERAKEVRGS
               70        80        90       100       110       120

                130       140       150       160       170        
pF1KB7 NGG--PDQGSVKKSSGSKGTKKFRLEGTLLRTYICHIIFKTLFEVGFIVGHYFLYGFRIL
       ..   :   ... :   .:. .. :.:::: ::.: :...: .:::::::.::.::. . 
NP_005 GSYEYPVAEKAELSCWEEGNGRIALQGTLLNTYVCSILIRTTMEVGFIVGQYFIYGIFLT
              130       140       150       160       170       180

      180       190       200       210       220       230        
pF1KB7 PLYRCSRWPCPNVVDCFVSRPTEKTIFILFMLSVASVSLFLNVMELGHLGLKGIRSALKR
        :. : : :::. :.:.:::::::..::.:::.::..::.:.. :: ::: : ::. . .
NP_005 TLHVCRRSPCPHPVNCYVSRPTEKNVFIVFMLAVAALSLLLSLAELYHLGWKKIRQRFVK
              190       200       210       220       230       240

      240       250       260       270       280       290        
pF1KB7 PVEQPLGEIPEKSLHSIAVSSIQKAKGYQLLEEEKIVSHYFPLTEVGMVETSPLPAKPFN
       :                                                           
NP_005 PRQHMAKCQLSGPSVGIVQSCTPPPDFNQCLENGPGGKFFNPFSNNMASQQNTDNLVTEQ
              250       260       270       280       290       300

>>XP_005273008 (OMIM: 108770,121013,612474,614049) PREDI  (358 aa)
 initn: 1104 init1: 649 opt: 1032  Z-score: 870.4  bits: 169.9 E(85289): 9.6e-42
Smith-Waterman score: 1032; 61.8% identity (83.8% similar) in 241 aa overlap (1-239:1-241)

               10        20        30        40        50        60
pF1KB7 MGDWSFLGNILEEVNEHSTVIGRVWLTVLFIFRILILGTAAEFVWGDEQSDFVCNTQQPG
       :::::::::.::::..::::.:.::::::::::.:.::::::  :::::.:: :.: :::
XP_005 MGDWSFLGNFLEEVHKHSTVVGKVWLTVLFIFRMLVLGTAAESSWGDEQADFRCDTIQPG
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB7 CENVCYDEAFPISHIRLWVLQIIFVSTPSLMYVGHAVHYVRMEEKRKSREAEELGQQAGT
       :.:::::.:::::::: :::::::::::::.:.:::.: :::.:::: ::::.  .  :.
XP_005 CQNVCYDQAFPISHIRYWVLQIIFVSTPSLVYMGHAMHTVRMQEKRKLREAERAKEVRGS
               70        80        90       100       110       120

                130       140       150       160       170        
pF1KB7 NGG--PDQGSVKKSSGSKGTKKFRLEGTLLRTYICHIIFKTLFEVGFIVGHYFLYGFRIL
       ..   :   ... :   .:. .. :.:::: ::.: :...: .:::::::.::.::. . 
XP_005 GSYEYPVAEKAELSCWEEGNGRIALQGTLLNTYVCSILIRTTMEVGFIVGQYFIYGIFLT
              130       140       150       160       170       180

      180       190       200       210       220       230        
pF1KB7 PLYRCSRWPCPNVVDCFVSRPTEKTIFILFMLSVASVSLFLNVMELGHLGLKGIRSALKR
        :. : : :::. :.:.:::::::..::.:::.::..::.:.. :: ::: : ::. . .
XP_005 TLHVCRRSPCPHPVNCYVSRPTEKNVFIVFMLAVAALSLLLSLAELYHLGWKKIRQRFVK
              190       200       210       220       230       240

      240       250       260       270       280       290        
pF1KB7 PVEQPLGEIPEKSLHSIAVSSIQKAKGYQLLEEEKIVSHYFPLTEVGMVETSPLPAKPFN
       :                                                           
XP_005 PRQHMAKCQLSGPSVGIVQSCTPPPDFNQCLENGPGGKFFNPFSNNMASQQNTDNLVTEQ
              250       260       270       280       290       300

>>NP_859054 (OMIM: 108770,121013,612474,614049) gap junc  (358 aa)
 initn: 1104 init1: 649 opt: 1032  Z-score: 870.4  bits: 169.9 E(85289): 9.6e-42
Smith-Waterman score: 1032; 61.8% identity (83.8% similar) in 241 aa overlap (1-239:1-241)

               10        20        30        40        50        60
pF1KB7 MGDWSFLGNILEEVNEHSTVIGRVWLTVLFIFRILILGTAAEFVWGDEQSDFVCNTQQPG
       :::::::::.::::..::::.:.::::::::::.:.::::::  :::::.:: :.: :::
NP_859 MGDWSFLGNFLEEVHKHSTVVGKVWLTVLFIFRMLVLGTAAESSWGDEQADFRCDTIQPG
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB7 CENVCYDEAFPISHIRLWVLQIIFVSTPSLMYVGHAVHYVRMEEKRKSREAEELGQQAGT
       :.:::::.:::::::: :::::::::::::.:.:::.: :::.:::: ::::.  .  :.
NP_859 CQNVCYDQAFPISHIRYWVLQIIFVSTPSLVYMGHAMHTVRMQEKRKLREAERAKEVRGS
               70        80        90       100       110       120

                130       140       150       160       170        
pF1KB7 NGG--PDQGSVKKSSGSKGTKKFRLEGTLLRTYICHIIFKTLFEVGFIVGHYFLYGFRIL
       ..   :   ... :   .:. .. :.:::: ::.: :...: .:::::::.::.::. . 
NP_859 GSYEYPVAEKAELSCWEEGNGRIALQGTLLNTYVCSILIRTTMEVGFIVGQYFIYGIFLT
              130       140       150       160       170       180

      180       190       200       210       220       230        
pF1KB7 PLYRCSRWPCPNVVDCFVSRPTEKTIFILFMLSVASVSLFLNVMELGHLGLKGIRSALKR
        :. : : :::. :.:.:::::::..::.:::.::..::.:.. :: ::: : ::. . .
NP_859 TLHVCRRSPCPHPVNCYVSRPTEKNVFIVFMLAVAALSLLLSLAELYHLGWKKIRQRFVK
              190       200       210       220       230       240

      240       250       260       270       280       290        
pF1KB7 PVEQPLGEIPEKSLHSIAVSSIQKAKGYQLLEEEKIVSHYFPLTEVGMVETSPLPAKPFN
       :                                                           
NP_859 PRQHMAKCQLSGPSVGIVQSCTPPPDFNQCLENGPGGKFFNPFSNNMASQQNTDNLVTEQ
              250       260       270       280       290       300

>>NP_115991 (OMIM: 611924) gap junction alpha-10 protein  (543 aa)
 initn: 973 init1: 557 opt: 955  Z-score: 803.9  bits: 158.2 E(85289): 4.9e-38
Smith-Waterman score: 963; 38.2% identity (66.2% similar) in 456 aa overlap (1-429:1-439)

               10        20        30        40        50        60
pF1KB7 MGDWSFLGNILEEVNEHSTVIGRVWLTVLFIFRILILGTAAEFVWGDEQSDFVCNTQQPG
       ::::..::.:::::. :::..:..:::.:::::.:.: .::: :: :::: :.:::.:::
NP_115 MGDWNLLGGILEEVHSHSTIVGKIWLTILFIFRMLVLRVAAEDVWDDEQSAFACNTRQPG
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB7 CENVCYDEAFPISHIRLWVLQIIFVSTPSLMYVGHAVHYVRMEEKRKSREAEELGQQAGT
       :.:.:::.::::: ::.:::::::::.:::.:.:::.. .:  :: ..:.  .:  :  .
NP_115 CNNICYDDAFPISLIRFWVLQIIFVSSPSLVYMGHALYRLRAFEKDRQRKKSHLRAQMEN
               70        80        90       100       110       120

                       130       140       150       160       170 
pF1KB7 NGGPD-----QGSV----KKSSGSKGTKKFRLEGTLLRTYICHIIFKTLFEVGFIVGHYF
          ::     :  .    ..   .:  .:  :.: :::::. ::. ....::::..:.:.
NP_115 ---PDLDLEEQQRIDRELRRLEEQKRIHKVPLKGCLLRTYVLHILTRSVLEVGFMIGQYI
                 130       140       150       160       170       

             180       190       200       210       220       230 
pF1KB7 LYGFRILPLYRCSRWPCPNVVDCFVSRPTEKTIFILFMLSVASVSLFLNVMELGHLGLKG
       ::::.. :::.:.. ::::.::::::::::::::.::: :.:..::.::..:. :::.. 
NP_115 LYGFQMHPLYKCTQPPCPNAVDCFVSRPTEKTIFMLFMHSIAAISLLLNILEIFHLGIRK
       180       190       200       210       220       230       

                  240       250            260        270       280
pF1KB7 I-RSALKRP----VEQPLGEIPEKSLHSIA-----VSSI-QKAKGYQLLEEEKIVSHYFP
       : :.  :.     .:.  :   . . .:.:      ::. .. .  :  ......    :
NP_115 IMRTLYKKSSSEGIEDETGPPFHLKKYSVAQQCMICSSLPERISPLQANNQQQVIRVNVP
       240       250       260       270       280       290       

              290       300       310       320       330       340
pF1KB7 LTEVGMVETSPLPAKPFNQFEEKISTGPLGDLSRGYQETLPSYAQVGAQEVEGEGPPAEE
        ... : .  : :     :.:   :.:   : :.  :..       :  .:..  : :  
NP_115 KSKT-MWQI-PQP----RQLEVDPSNGK-KDWSEKDQHS-------GQLHVHSPCPWAGS
       300             310        320              330       340   

              350            360       370       380       390     
pF1KB7 GAEPEVGEKKEEA-----ERLTTEEQEKVAVPEGEKVETPGVDKEGEKEEPQSEKVSKQG
       ... ..:......     . ..      ...:..    . :. ....  ::..: ..   
NP_115 AGNQHLGQQSDHSSFGLQNTMSQSWLGTTTAPRNCPSFAVGTWEQSQDPEPSGEPLTDLH
           350       360       370       380       390       400   

         400         410       420       430                       
pF1KB7 LPAEKTPSLCPE--LTTDDARPLSRLSKASSRARSDDLTV                    
          . . .   :  .  : .:: :: ..  ::  :.                        
NP_115 SHCRDSEGSMRESGVWIDRSRPGSRKASFLSRLLSEKRHLHSDSGSSGSRNSSCLDFPHW
           410       420       430       440       450       460   

NP_115 ENSPSPLPSVTGHRTSMVRQAALPIMELSQELFHSGCFLFPFFLPGVCMYVCVDREADGG
           470       480       490       500       510       520   




433 residues in 1 query   sequences
60827320 residues in 85289 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Fri Nov  4 05:34:54 2016 done: Fri Nov  4 05:34:56 2016
 Total Scan time: 10.120 Total Display time:  0.070

Function used was FASTA [36.3.4 Apr, 2011]
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