Result of FASTA (omim) for pF1KB7094
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KB7094, 186 aa
  1>>>pF1KB7094 186 - 186 aa - 186 aa
Library: /omim/omim.rfq.tfa
  60827320 residues in 85289 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 5.0366+/-0.000346; mu= 14.0394+/- 0.021
 mean_var=60.8626+/-12.102, 0's: 0 Z-trim(113.5): 20  B-trim: 20 in 1/50
 Lambda= 0.164399
 statistics sampled from 22805 (22825) to 22805 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.656), E-opt: 0.2 (0.268), width:  16
 Scan time:  5.840

The best scores are:                                      opt bits E(85289)
XP_011525982 (OMIM: 615869) PREDICTED: tumor necro ( 186) 1202 293.3 1.5e-79
XP_005259544 (OMIM: 615869) PREDICTED: tumor necro ( 186) 1202 293.3 1.5e-79
NP_689575 (OMIM: 615869) tumor necrosis factor alp ( 186) 1202 293.3 1.5e-79
NP_001161414 (OMIM: 615869) tumor necrosis factor  ( 186) 1202 293.3 1.5e-79
NP_001071122 (OMIM: 612111) tumor necrosis factor  ( 188)  754 187.1 1.4e-47
NP_001273742 (OMIM: 612111) tumor necrosis factor  ( 198)  754 187.1 1.5e-47
NP_055165 (OMIM: 612111) tumor necrosis factor alp ( 198)  754 187.1 1.5e-47
XP_016864816 (OMIM: 612111) PREDICTED: tumor necro ( 201)  754 187.1 1.5e-47
NP_001273743 (OMIM: 612111) tumor necrosis factor  ( 210)  754 187.1 1.6e-47
XP_016877657 (OMIM: 616438) PREDICTED: tumor necro ( 203)  694 172.9   3e-43
NP_001298104 (OMIM: 616438) tumor necrosis factor  ( 204)  694 172.9   3e-43
XP_011519847 (OMIM: 616438) PREDICTED: tumor necro ( 218)  694 172.9 3.1e-43
NP_997264 (OMIM: 616438) tumor necrosis factor alp ( 292)  694 173.0   4e-43
NP_078851 (OMIM: 612112) tumor necrosis factor alp ( 184)  678 169.0 3.8e-42
NP_001273746 (OMIM: 612111) tumor necrosis factor  ( 166)  673 167.8 7.9e-42
NP_001273744 (OMIM: 612111) tumor necrosis factor  ( 166)  673 167.8 7.9e-42
XP_016864817 (OMIM: 612111) PREDICTED: tumor necro ( 166)  673 167.8 7.9e-42
XP_016877658 (OMIM: 616438) PREDICTED: tumor necro ( 158)  574 144.3 8.9e-35


>>XP_011525982 (OMIM: 615869) PREDICTED: tumor necrosis   (186 aa)
 initn: 1202 init1: 1202 opt: 1202  Z-score: 1549.3  bits: 293.3 E(85289): 1.5e-79
Smith-Waterman score: 1202; 100.0% identity (100.0% similar) in 186 aa overlap (1-186:1-186)

               10        20        30        40        50        60
pF1KB7 MDTFSTKSLALQAQKKLLSKMASKAVVAVLVDDTSSEVLDELYRATREFTRSRKEAQKML
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MDTFSTKSLALQAQKKLLSKMASKAVVAVLVDDTSSEVLDELYRATREFTRSRKEAQKML
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB7 KNLVKVALKLGLLLRGDQLGGEELALLRRFRHRARCLAMTAVSFHQVDFTFDRRVLAAGL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KNLVKVALKLGLLLRGDQLGGEELALLRRFRHRARCLAMTAVSFHQVDFTFDRRVLAAGL
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB7 LECRDLLHQAVGPHLTAKSHGRINHVFGHLADCDFLAALYGPAEPYRSHLRRICEGLGRM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LECRDLLHQAVGPHLTAKSHGRINHVFGHLADCDFLAALYGPAEPYRSHLRRICEGLGRM
              130       140       150       160       170       180

             
pF1KB7 LDEGSL
       ::::::
XP_011 LDEGSL
             

>>XP_005259544 (OMIM: 615869) PREDICTED: tumor necrosis   (186 aa)
 initn: 1202 init1: 1202 opt: 1202  Z-score: 1549.3  bits: 293.3 E(85289): 1.5e-79
Smith-Waterman score: 1202; 100.0% identity (100.0% similar) in 186 aa overlap (1-186:1-186)

               10        20        30        40        50        60
pF1KB7 MDTFSTKSLALQAQKKLLSKMASKAVVAVLVDDTSSEVLDELYRATREFTRSRKEAQKML
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MDTFSTKSLALQAQKKLLSKMASKAVVAVLVDDTSSEVLDELYRATREFTRSRKEAQKML
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB7 KNLVKVALKLGLLLRGDQLGGEELALLRRFRHRARCLAMTAVSFHQVDFTFDRRVLAAGL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 KNLVKVALKLGLLLRGDQLGGEELALLRRFRHRARCLAMTAVSFHQVDFTFDRRVLAAGL
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB7 LECRDLLHQAVGPHLTAKSHGRINHVFGHLADCDFLAALYGPAEPYRSHLRRICEGLGRM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LECRDLLHQAVGPHLTAKSHGRINHVFGHLADCDFLAALYGPAEPYRSHLRRICEGLGRM
              130       140       150       160       170       180

             
pF1KB7 LDEGSL
       ::::::
XP_005 LDEGSL
             

>>NP_689575 (OMIM: 615869) tumor necrosis factor alpha-i  (186 aa)
 initn: 1202 init1: 1202 opt: 1202  Z-score: 1549.3  bits: 293.3 E(85289): 1.5e-79
Smith-Waterman score: 1202; 100.0% identity (100.0% similar) in 186 aa overlap (1-186:1-186)

               10        20        30        40        50        60
pF1KB7 MDTFSTKSLALQAQKKLLSKMASKAVVAVLVDDTSSEVLDELYRATREFTRSRKEAQKML
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_689 MDTFSTKSLALQAQKKLLSKMASKAVVAVLVDDTSSEVLDELYRATREFTRSRKEAQKML
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB7 KNLVKVALKLGLLLRGDQLGGEELALLRRFRHRARCLAMTAVSFHQVDFTFDRRVLAAGL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_689 KNLVKVALKLGLLLRGDQLGGEELALLRRFRHRARCLAMTAVSFHQVDFTFDRRVLAAGL
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB7 LECRDLLHQAVGPHLTAKSHGRINHVFGHLADCDFLAALYGPAEPYRSHLRRICEGLGRM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_689 LECRDLLHQAVGPHLTAKSHGRINHVFGHLADCDFLAALYGPAEPYRSHLRRICEGLGRM
              130       140       150       160       170       180

             
pF1KB7 LDEGSL
       ::::::
NP_689 LDEGSL
             

>>NP_001161414 (OMIM: 615869) tumor necrosis factor alph  (186 aa)
 initn: 1202 init1: 1202 opt: 1202  Z-score: 1549.3  bits: 293.3 E(85289): 1.5e-79
Smith-Waterman score: 1202; 100.0% identity (100.0% similar) in 186 aa overlap (1-186:1-186)

               10        20        30        40        50        60
pF1KB7 MDTFSTKSLALQAQKKLLSKMASKAVVAVLVDDTSSEVLDELYRATREFTRSRKEAQKML
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MDTFSTKSLALQAQKKLLSKMASKAVVAVLVDDTSSEVLDELYRATREFTRSRKEAQKML
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB7 KNLVKVALKLGLLLRGDQLGGEELALLRRFRHRARCLAMTAVSFHQVDFTFDRRVLAAGL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KNLVKVALKLGLLLRGDQLGGEELALLRRFRHRARCLAMTAVSFHQVDFTFDRRVLAAGL
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB7 LECRDLLHQAVGPHLTAKSHGRINHVFGHLADCDFLAALYGPAEPYRSHLRRICEGLGRM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LECRDLLHQAVGPHLTAKSHGRINHVFGHLADCDFLAALYGPAEPYRSHLRRICEGLGRM
              130       140       150       160       170       180

             
pF1KB7 LDEGSL
       ::::::
NP_001 LDEGSL
             

>>NP_001071122 (OMIM: 612111) tumor necrosis factor alph  (188 aa)
 initn: 754 init1: 754 opt: 754  Z-score: 975.0  bits: 187.1 E(85289): 1.4e-47
Smith-Waterman score: 754; 57.7% identity (91.8% similar) in 182 aa overlap (2-183:4-185)

                 10        20        30        40        50        
pF1KB7   MDTFSTKSLALQAQKKLLSKMASKAVVAVLVDDTSSEVLDELYRATREFTRSRKEAQK
          :.:..:.::.:::::.:.::.::.....:.:::::::::::::.:::.:...:::.:
NP_001 MATDVFNSKNLAVQAQKKILGKMVSKSIATTLIDDTSSEVLDELYRVTREYTQNKKEAEK
               10        20        30        40        50        60

       60        70        80        90       100       110        
pF1KB7 MLKNLVKVALKLGLLLRGDQLGGEELALLRRFRHRARCLAMTAVSFHQVDFTFDRRVLAA
       ..:::.:...::..: :..:.. .::::...:..... ::::.:::::::.:::: ::. 
NP_001 IIKNLIKTVIKLAILYRNNQFNQDELALMEKFKKKVHQLAMTVVSFHQVDYTFDRNVLSR
               70        80        90       100       110       120

      120       130       140       150       160       170        
pF1KB7 GLLECRDLLHQAVGPHLTAKSHGRINHVFGHLADCDFLAALYGPAEPYRSHLRRICEGLG
        : :::..::: .  :::::::::.:.:: :..::.::::::.:   .. ::...:.:..
NP_001 LLNECREMLHQIIQRHLTAKSHGRVNNVFDHFSDCEFLAALYNPFGNFKPHLQKLCDGIN
              130       140       150       160       170       180

      180      
pF1KB7 RMLDEGSL
       .::::   
NP_001 KMLDEENI
               

>>NP_001273742 (OMIM: 612111) tumor necrosis factor alph  (198 aa)
 initn: 754 init1: 754 opt: 754  Z-score: 974.6  bits: 187.1 E(85289): 1.5e-47
Smith-Waterman score: 754; 57.7% identity (91.8% similar) in 182 aa overlap (2-183:14-195)

                           10        20        30        40        
pF1KB7             MDTFSTKSLALQAQKKLLSKMASKAVVAVLVDDTSSEVLDELYRATRE
                    :.:..:.::.:::::.:.::.::.....:.:::::::::::::.:::
NP_001 MHSEAEESKEVATDVFNSKNLAVQAQKKILGKMVSKSIATTLIDDTSSEVLDELYRVTRE
               10        20        30        40        50        60

       50        60        70        80        90       100        
pF1KB7 FTRSRKEAQKMLKNLVKVALKLGLLLRGDQLGGEELALLRRFRHRARCLAMTAVSFHQVD
       .:...:::.:..:::.:...::..: :..:.. .::::...:..... ::::.:::::::
NP_001 YTQNKKEAEKIIKNLIKTVIKLAILYRNNQFNQDELALMEKFKKKVHQLAMTVVSFHQVD
               70        80        90       100       110       120

      110       120       130       140       150       160        
pF1KB7 FTFDRRVLAAGLLECRDLLHQAVGPHLTAKSHGRINHVFGHLADCDFLAALYGPAEPYRS
       .:::: ::.  : :::..::: .  :::::::::.:.:: :..::.::::::.:   .. 
NP_001 YTFDRNVLSRLLNECREMLHQIIQRHLTAKSHGRVNNVFDHFSDCEFLAALYNPFGNFKP
              130       140       150       160       170       180

      170       180      
pF1KB7 HLRRICEGLGRMLDEGSL
       ::...:.:...::::   
NP_001 HLQKLCDGINKMLDEENI
              190        

>>NP_055165 (OMIM: 612111) tumor necrosis factor alpha-i  (198 aa)
 initn: 754 init1: 754 opt: 754  Z-score: 974.6  bits: 187.1 E(85289): 1.5e-47
Smith-Waterman score: 754; 57.7% identity (91.8% similar) in 182 aa overlap (2-183:14-195)

                           10        20        30        40        
pF1KB7             MDTFSTKSLALQAQKKLLSKMASKAVVAVLVDDTSSEVLDELYRATRE
                    :.:..:.::.:::::.:.::.::.....:.:::::::::::::.:::
NP_055 MHSEAEESKEVATDVFNSKNLAVQAQKKILGKMVSKSIATTLIDDTSSEVLDELYRVTRE
               10        20        30        40        50        60

       50        60        70        80        90       100        
pF1KB7 FTRSRKEAQKMLKNLVKVALKLGLLLRGDQLGGEELALLRRFRHRARCLAMTAVSFHQVD
       .:...:::.:..:::.:...::..: :..:.. .::::...:..... ::::.:::::::
NP_055 YTQNKKEAEKIIKNLIKTVIKLAILYRNNQFNQDELALMEKFKKKVHQLAMTVVSFHQVD
               70        80        90       100       110       120

      110       120       130       140       150       160        
pF1KB7 FTFDRRVLAAGLLECRDLLHQAVGPHLTAKSHGRINHVFGHLADCDFLAALYGPAEPYRS
       .:::: ::.  : :::..::: .  :::::::::.:.:: :..::.::::::.:   .. 
NP_055 YTFDRNVLSRLLNECREMLHQIIQRHLTAKSHGRVNNVFDHFSDCEFLAALYNPFGNFKP
              130       140       150       160       170       180

      170       180      
pF1KB7 HLRRICEGLGRMLDEGSL
       ::...:.:...::::   
NP_055 HLQKLCDGINKMLDEENI
              190        

>>XP_016864816 (OMIM: 612111) PREDICTED: tumor necrosis   (201 aa)
 initn: 754 init1: 754 opt: 754  Z-score: 974.5  bits: 187.1 E(85289): 1.5e-47
Smith-Waterman score: 754; 57.7% identity (91.8% similar) in 182 aa overlap (2-183:17-198)

                              10        20        30        40     
pF1KB7                MDTFSTKSLALQAQKKLLSKMASKAVVAVLVDDTSSEVLDELYRA
                       :.:..:.::.:::::.:.::.::.....:.:::::::::::::.
XP_016 MAKGGDTETEREGVATDVFNSKNLAVQAQKKILGKMVSKSIATTLIDDTSSEVLDELYRV
               10        20        30        40        50        60

          50        60        70        80        90       100     
pF1KB7 TREFTRSRKEAQKMLKNLVKVALKLGLLLRGDQLGGEELALLRRFRHRARCLAMTAVSFH
       :::.:...:::.:..:::.:...::..: :..:.. .::::...:..... ::::.::::
XP_016 TREYTQNKKEAEKIIKNLIKTVIKLAILYRNNQFNQDELALMEKFKKKVHQLAMTVVSFH
               70        80        90       100       110       120

         110       120       130       140       150       160     
pF1KB7 QVDFTFDRRVLAAGLLECRDLLHQAVGPHLTAKSHGRINHVFGHLADCDFLAALYGPAEP
       :::.:::: ::.  : :::..::: .  :::::::::.:.:: :..::.::::::.:   
XP_016 QVDYTFDRNVLSRLLNECREMLHQIIQRHLTAKSHGRVNNVFDHFSDCEFLAALYNPFGN
              130       140       150       160       170       180

         170       180      
pF1KB7 YRSHLRRICEGLGRMLDEGSL
       .. ::...:.:...::::   
XP_016 FKPHLQKLCDGINKMLDEENI
              190       200 

>>NP_001273743 (OMIM: 612111) tumor necrosis factor alph  (210 aa)
 initn: 754 init1: 754 opt: 754  Z-score: 974.2  bits: 187.1 E(85289): 1.6e-47
Smith-Waterman score: 754; 57.7% identity (91.8% similar) in 182 aa overlap (2-183:26-207)

                                       10        20        30      
pF1KB7                         MDTFSTKSLALQAQKKLLSKMASKAVVAVLVDDTSS
                                :.:..:.::.:::::.:.::.::.....:.:::::
NP_001 MTLPRYCEVVLLIAHGEKMLKLVATDVFNSKNLAVQAQKKILGKMVSKSIATTLIDDTSS
               10        20        30        40        50        60

         40        50        60        70        80        90      
pF1KB7 EVLDELYRATREFTRSRKEAQKMLKNLVKVALKLGLLLRGDQLGGEELALLRRFRHRARC
       ::::::::.:::.:...:::.:..:::.:...::..: :..:.. .::::...:..... 
NP_001 EVLDELYRVTREYTQNKKEAEKIIKNLIKTVIKLAILYRNNQFNQDELALMEKFKKKVHQ
               70        80        90       100       110       120

        100       110       120       130       140       150      
pF1KB7 LAMTAVSFHQVDFTFDRRVLAAGLLECRDLLHQAVGPHLTAKSHGRINHVFGHLADCDFL
       ::::.:::::::.:::: ::.  : :::..::: .  :::::::::.:.:: :..::.::
NP_001 LAMTVVSFHQVDYTFDRNVLSRLLNECREMLHQIIQRHLTAKSHGRVNNVFDHFSDCEFL
              130       140       150       160       170       180

        160       170       180      
pF1KB7 AALYGPAEPYRSHLRRICEGLGRMLDEGSL
       ::::.:   .. ::...:.:...::::   
NP_001 AALYNPFGNFKPHLQKLCDGINKMLDEENI
              190       200       210

>>XP_016877657 (OMIM: 616438) PREDICTED: tumor necrosis   (203 aa)
 initn: 686 init1: 686 opt: 694  Z-score: 897.6  bits: 172.9 E(85289): 3e-43
Smith-Waterman score: 694; 55.1% identity (85.9% similar) in 185 aa overlap (2-186:19-203)

                                10        20        30        40   
pF1KB7                  MDTFSTKSLALQAQKKLLSKMASKAVVAVLVDDTSSEVLDELY
                         :.::.::::::::::.:::.:::.:. .:.::::::..::::
XP_016 MIHPPVASQVSASVSSGPDVFSSKSLALQAQKKILSKIASKTVANMLIDDTSSEIFDELY
               10        20        30        40        50        60

            50        60        70        80        90       100   
pF1KB7 RATREFTRSRKEAQKMLKNLVKVALKLGLLLRGDQLGGEELALLRRFRHRARCLAMTAVS
       ..:.: :...:::.:..:.:.:::.:.:.: :..:.. :::.....::..    ::: ::
XP_016 KVTKEHTHNKKEAHKIMKDLIKVAIKIGILYRNNQFSQEELVIVEKFRKKLNQTAMTIVS
               70        80        90       100       110       120

           110       120       130       140       150       160   
pF1KB7 FHQVDFTFDRRVLAAGLLECRDLLHQAVGPHLTAKSHGRINHVFGHLADCDFLAALYGPA
       :..:..:::: ::.  : ::.::.:. :  ::: ..::::::::.:.:: .::..::.  
XP_016 FYEVEYTFDRNVLSNLLHECKDLVHELVQRHLTPRTHGRINHVFNHFADVEFLSTLYSLD
              130       140       150       160       170       180

           170       180      
pF1KB7 EPYRSHLRRICEGLGRMLDEGSL
          : .:.:::::....:::  :
XP_016 GDCRPNLKRICEGINKLLDEKVL
              190       200   




186 residues in 1 query   sequences
60827320 residues in 85289 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Fri Nov  4 04:39:28 2016 done: Fri Nov  4 04:39:29 2016
 Total Scan time:  5.840 Total Display time: -0.020

Function used was FASTA [36.3.4 Apr, 2011]
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