Result of FASTA (omim) for pF1KB7035
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KB7035, 426 aa
  1>>>pF1KB7035 426 - 426 aa - 426 aa
Library: /omim/omim.rfq.tfa
  60827320 residues in 85289 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 5.5955+/-0.000304; mu= 17.2265+/- 0.019
 mean_var=83.9208+/-16.654, 0's: 0 Z-trim(117.8): 71  B-trim: 1066 in 1/53
 Lambda= 0.140004
 statistics sampled from 29993 (30064) to 29993 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.712), E-opt: 0.2 (0.352), width:  16
 Scan time:  8.420

The best scores are:                                      opt bits E(85289)
NP_002183 (OMIM: 147290) inhibin beta A chain prep ( 426) 2895 594.2  2e-169
XP_016867665 (OMIM: 147290) PREDICTED: inhibin bet ( 426) 2895 594.2  2e-169
XP_016867664 (OMIM: 147290) PREDICTED: inhibin bet ( 483) 2895 594.3 2.3e-169
XP_016867663 (OMIM: 147290) PREDICTED: inhibin bet ( 548) 2895 594.3 2.5e-169
NP_002184 (OMIM: 147390) inhibin beta B chain prep ( 407)  700 150.9 5.7e-36
NP_005529 (OMIM: 601233) inhibin beta C chain prep ( 352)  523 115.1   3e-25
NP_113667 (OMIM: 612031) inhibin beta E chain prep ( 350)  500 110.4 7.4e-24
XP_011527625 (OMIM: 112261,112600,235200) PREDICTE ( 240)  393 88.7 1.8e-17
NP_001191 (OMIM: 112261,112600,235200) bone morpho ( 396)  393 88.8 2.6e-17
NP_065685 (OMIM: 606522,613702,613703,613704) grow ( 364)  380 86.2 1.5e-16
NP_001001557 (OMIM: 118100,601147,613094,613703,61 ( 455)  368 83.8 9.6e-16
XP_016877093 (OMIM: 112262,600625,607932) PREDICTE ( 345)  361 82.3 2.1e-15
XP_016877094 (OMIM: 112262,600625,607932) PREDICTE ( 345)  361 82.3 2.1e-15
XP_016877092 (OMIM: 112262,600625,607932) PREDICTE ( 408)  361 82.4 2.3e-15
NP_570911 (OMIM: 112262,600625,607932) bone morpho ( 408)  361 82.4 2.3e-15
XP_005268072 (OMIM: 112262,600625,607932) PREDICTE ( 408)  361 82.4 2.3e-15
NP_001193 (OMIM: 112262,600625,607932) bone morpho ( 408)  361 82.4 2.3e-15
NP_001711 (OMIM: 602284) bone morphogenetic protei ( 402)  358 81.8 3.5e-15
NP_001483 (OMIM: 187500,208530,217095,602880,61385 ( 372)  357 81.5 3.8e-15
XP_011540326 (OMIM: 602284) PREDICTED: bone morpho ( 427)  350 80.2 1.1e-14
XP_016866687 (OMIM: 112265) PREDICTED: bone morpho ( 239)  344 78.8 1.7e-14
NP_066551 (OMIM: 112265) bone morphogenetic protei ( 454)  344 79.0 2.8e-14
NP_001709 (OMIM: 112266) bone morphogenetic protei ( 513)  342 78.6   4e-14
NP_001710 (OMIM: 112267) bone morphogenetic protei ( 431)  340 78.2 4.6e-14
NP_000651 (OMIM: 131300,190180,219700) transformin ( 390)  317 73.5 1.1e-12
XP_011525544 (OMIM: 131300,190180,219700) PREDICTE ( 391)  317 73.5 1.1e-12
NP_003230 (OMIM: 107970,190230,615582) transformin ( 412)  317 73.5 1.1e-12
NP_001316868 (OMIM: 107970,190230,615582) transfor ( 412)  317 73.5 1.1e-12
NP_001316835 (OMIM: 270100,601265) nodal homolog i ( 214)  313 72.5 1.2e-12
NP_001306067 (OMIM: 112600,113100,200700,201250,22 ( 501)  317 73.6 1.3e-12
XP_011527377 (OMIM: 112600,113100,200700,201250,22 ( 501)  317 73.6 1.3e-12
NP_000548 (OMIM: 112600,113100,200700,201250,22890 ( 501)  317 73.6 1.3e-12
NP_060525 (OMIM: 270100,601265) nodal homolog isof ( 347)  313 72.6 1.7e-12
NP_878248 (OMIM: 604651) growth/differentiation fa ( 450)  312 72.5 2.4e-12
NP_001192 (OMIM: 112263) bone morphogenetic protei ( 472)  299 69.9 1.5e-11
NP_003229 (OMIM: 190220,614816) transforming growt ( 414)  297 69.5 1.8e-11
NP_001129071 (OMIM: 190220,614816) transforming gr ( 442)  297 69.5 1.9e-11
NP_055297 (OMIM: 608748) bone morphogenetic protei ( 424)  293 68.7 3.3e-11
NP_057288 (OMIM: 605120,615506) growth/differentia ( 429)  277 65.4 3.1e-10
NP_004953 (OMIM: 601361) growth/differentiation fa ( 478)  269 63.9   1e-09
XP_011541613 (OMIM: 601918) PREDICTED: growth/diff ( 276)  241 58.0 3.4e-08
XP_006714648 (OMIM: 601918) PREDICTED: growth/diff ( 366)  241 58.1 4.3e-08
NP_001275756 (OMIM: 601918) growth/differentiation ( 366)  241 58.1 4.3e-08
XP_011541612 (OMIM: 601918) PREDICTED: growth/diff ( 366)  241 58.1 4.3e-08
XP_005272014 (OMIM: 601918) PREDICTED: growth/diff ( 366)  241 58.1 4.3e-08
NP_001275755 (OMIM: 601918) growth/differentiation ( 366)  241 58.1 4.3e-08
XP_011541611 (OMIM: 601918) PREDICTED: growth/diff ( 366)  241 58.1 4.3e-08
NP_001275754 (OMIM: 601918) growth/differentiation ( 366)  241 58.1 4.3e-08
NP_001275757 (OMIM: 601918) growth/differentiation ( 366)  241 58.1 4.3e-08
NP_001275753 (OMIM: 601918) growth/differentiation ( 366)  241 58.1 4.3e-08


>>NP_002183 (OMIM: 147290) inhibin beta A chain prepropr  (426 aa)
 initn: 2895 init1: 2895 opt: 2895  Z-score: 3162.5  bits: 594.2 E(85289): 2e-169
Smith-Waterman score: 2895; 100.0% identity (100.0% similar) in 426 aa overlap (1-426:1-426)

               10        20        30        40        50        60
pF1KB7 MPLLWLRGFLLASCWIIVRSSPTPGSEGHSAAPDCPSCALAALPKDVPNSQPEMVEAVKK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 MPLLWLRGFLLASCWIIVRSSPTPGSEGHSAAPDCPSCALAALPKDVPNSQPEMVEAVKK
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB7 HILNMLHLKKRPDVTQPVPKAALLNAIRKLHVGKVGENGYVEIEDDIGRRAEMNELMEQT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 HILNMLHLKKRPDVTQPVPKAALLNAIRKLHVGKVGENGYVEIEDDIGRRAEMNELMEQT
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB7 SEIITFAESGTARKTLHFEISKEGSDLSVVERAEVWLFLKVPKANRTRTKVTIRLFQQQK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 SEIITFAESGTARKTLHFEISKEGSDLSVVERAEVWLFLKVPKANRTRTKVTIRLFQQQK
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB7 HPQGSLDTGEEAEEVGLKGERSELLLSEKVVDARKSTWHVFPVSSSIQRLLDQGKSSLDV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 HPQGSLDTGEEAEEVGLKGERSELLLSEKVVDARKSTWHVFPVSSSIQRLLDQGKSSLDV
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB7 RIACEQCQESGASLVLLGKKKKKEEEGEGKKKGGGEGGAGADEEKEQSHRPFLMLQARQS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 RIACEQCQESGASLVLLGKKKKKEEEGEGKKKGGGEGGAGADEEKEQSHRPFLMLQARQS
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KB7 EDHPHRRRRRGLECDGKVNICCKKQFFVSFKDIGWNDWIIAPSGYHANYCEGECPSHIAG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 EDHPHRRRRRGLECDGKVNICCKKQFFVSFKDIGWNDWIIAPSGYHANYCEGECPSHIAG
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KB7 TSGSSLSFHSTVINHYRMRGHSPFANLKSCCVPTKLRPMSMLYYDDGQNIIKKDIQNMIV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 TSGSSLSFHSTVINHYRMRGHSPFANLKSCCVPTKLRPMSMLYYDDGQNIIKKDIQNMIV
              370       380       390       400       410       420

             
pF1KB7 EECGCS
       ::::::
NP_002 EECGCS
             

>>XP_016867665 (OMIM: 147290) PREDICTED: inhibin beta A   (426 aa)
 initn: 2895 init1: 2895 opt: 2895  Z-score: 3162.5  bits: 594.2 E(85289): 2e-169
Smith-Waterman score: 2895; 100.0% identity (100.0% similar) in 426 aa overlap (1-426:1-426)

               10        20        30        40        50        60
pF1KB7 MPLLWLRGFLLASCWIIVRSSPTPGSEGHSAAPDCPSCALAALPKDVPNSQPEMVEAVKK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MPLLWLRGFLLASCWIIVRSSPTPGSEGHSAAPDCPSCALAALPKDVPNSQPEMVEAVKK
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB7 HILNMLHLKKRPDVTQPVPKAALLNAIRKLHVGKVGENGYVEIEDDIGRRAEMNELMEQT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 HILNMLHLKKRPDVTQPVPKAALLNAIRKLHVGKVGENGYVEIEDDIGRRAEMNELMEQT
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB7 SEIITFAESGTARKTLHFEISKEGSDLSVVERAEVWLFLKVPKANRTRTKVTIRLFQQQK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SEIITFAESGTARKTLHFEISKEGSDLSVVERAEVWLFLKVPKANRTRTKVTIRLFQQQK
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB7 HPQGSLDTGEEAEEVGLKGERSELLLSEKVVDARKSTWHVFPVSSSIQRLLDQGKSSLDV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 HPQGSLDTGEEAEEVGLKGERSELLLSEKVVDARKSTWHVFPVSSSIQRLLDQGKSSLDV
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB7 RIACEQCQESGASLVLLGKKKKKEEEGEGKKKGGGEGGAGADEEKEQSHRPFLMLQARQS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RIACEQCQESGASLVLLGKKKKKEEEGEGKKKGGGEGGAGADEEKEQSHRPFLMLQARQS
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KB7 EDHPHRRRRRGLECDGKVNICCKKQFFVSFKDIGWNDWIIAPSGYHANYCEGECPSHIAG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EDHPHRRRRRGLECDGKVNICCKKQFFVSFKDIGWNDWIIAPSGYHANYCEGECPSHIAG
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KB7 TSGSSLSFHSTVINHYRMRGHSPFANLKSCCVPTKLRPMSMLYYDDGQNIIKKDIQNMIV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TSGSSLSFHSTVINHYRMRGHSPFANLKSCCVPTKLRPMSMLYYDDGQNIIKKDIQNMIV
              370       380       390       400       410       420

             
pF1KB7 EECGCS
       ::::::
XP_016 EECGCS
             

>>XP_016867664 (OMIM: 147290) PREDICTED: inhibin beta A   (483 aa)
 initn: 2895 init1: 2895 opt: 2895  Z-score: 3161.8  bits: 594.3 E(85289): 2.3e-169
Smith-Waterman score: 2895; 100.0% identity (100.0% similar) in 426 aa overlap (1-426:58-483)

                                             10        20        30
pF1KB7                               MPLLWLRGFLLASCWIIVRSSPTPGSEGHS
                                     ::::::::::::::::::::::::::::::
XP_016 KSTHTKKPAREGGGKAGPFKKAITTTFAARMPLLWLRGFLLASCWIIVRSSPTPGSEGHS
        30        40        50        60        70        80       

               40        50        60        70        80        90
pF1KB7 AAPDCPSCALAALPKDVPNSQPEMVEAVKKHILNMLHLKKRPDVTQPVPKAALLNAIRKL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AAPDCPSCALAALPKDVPNSQPEMVEAVKKHILNMLHLKKRPDVTQPVPKAALLNAIRKL
        90       100       110       120       130       140       

              100       110       120       130       140       150
pF1KB7 HVGKVGENGYVEIEDDIGRRAEMNELMEQTSEIITFAESGTARKTLHFEISKEGSDLSVV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 HVGKVGENGYVEIEDDIGRRAEMNELMEQTSEIITFAESGTARKTLHFEISKEGSDLSVV
       150       160       170       180       190       200       

              160       170       180       190       200       210
pF1KB7 ERAEVWLFLKVPKANRTRTKVTIRLFQQQKHPQGSLDTGEEAEEVGLKGERSELLLSEKV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ERAEVWLFLKVPKANRTRTKVTIRLFQQQKHPQGSLDTGEEAEEVGLKGERSELLLSEKV
       210       220       230       240       250       260       

              220       230       240       250       260       270
pF1KB7 VDARKSTWHVFPVSSSIQRLLDQGKSSLDVRIACEQCQESGASLVLLGKKKKKEEEGEGK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VDARKSTWHVFPVSSSIQRLLDQGKSSLDVRIACEQCQESGASLVLLGKKKKKEEEGEGK
       270       280       290       300       310       320       

              280       290       300       310       320       330
pF1KB7 KKGGGEGGAGADEEKEQSHRPFLMLQARQSEDHPHRRRRRGLECDGKVNICCKKQFFVSF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KKGGGEGGAGADEEKEQSHRPFLMLQARQSEDHPHRRRRRGLECDGKVNICCKKQFFVSF
       330       340       350       360       370       380       

              340       350       360       370       380       390
pF1KB7 KDIGWNDWIIAPSGYHANYCEGECPSHIAGTSGSSLSFHSTVINHYRMRGHSPFANLKSC
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KDIGWNDWIIAPSGYHANYCEGECPSHIAGTSGSSLSFHSTVINHYRMRGHSPFANLKSC
       390       400       410       420       430       440       

              400       410       420      
pF1KB7 CVPTKLRPMSMLYYDDGQNIIKKDIQNMIVEECGCS
       ::::::::::::::::::::::::::::::::::::
XP_016 CVPTKLRPMSMLYYDDGQNIIKKDIQNMIVEECGCS
       450       460       470       480   

>>XP_016867663 (OMIM: 147290) PREDICTED: inhibin beta A   (548 aa)
 initn: 2895 init1: 2895 opt: 2895  Z-score: 3161.0  bits: 594.3 E(85289): 2.5e-169
Smith-Waterman score: 2895; 100.0% identity (100.0% similar) in 426 aa overlap (1-426:123-548)

                                             10        20        30
pF1KB7                               MPLLWLRGFLLASCWIIVRSSPTPGSEGHS
                                     ::::::::::::::::::::::::::::::
XP_016 KSTHTKKPAREGGGKAGPFKKAITTTFAARMPLLWLRGFLLASCWIIVRSSPTPGSEGHS
            100       110       120       130       140       150  

               40        50        60        70        80        90
pF1KB7 AAPDCPSCALAALPKDVPNSQPEMVEAVKKHILNMLHLKKRPDVTQPVPKAALLNAIRKL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AAPDCPSCALAALPKDVPNSQPEMVEAVKKHILNMLHLKKRPDVTQPVPKAALLNAIRKL
            160       170       180       190       200       210  

              100       110       120       130       140       150
pF1KB7 HVGKVGENGYVEIEDDIGRRAEMNELMEQTSEIITFAESGTARKTLHFEISKEGSDLSVV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 HVGKVGENGYVEIEDDIGRRAEMNELMEQTSEIITFAESGTARKTLHFEISKEGSDLSVV
            220       230       240       250       260       270  

              160       170       180       190       200       210
pF1KB7 ERAEVWLFLKVPKANRTRTKVTIRLFQQQKHPQGSLDTGEEAEEVGLKGERSELLLSEKV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ERAEVWLFLKVPKANRTRTKVTIRLFQQQKHPQGSLDTGEEAEEVGLKGERSELLLSEKV
            280       290       300       310       320       330  

              220       230       240       250       260       270
pF1KB7 VDARKSTWHVFPVSSSIQRLLDQGKSSLDVRIACEQCQESGASLVLLGKKKKKEEEGEGK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VDARKSTWHVFPVSSSIQRLLDQGKSSLDVRIACEQCQESGASLVLLGKKKKKEEEGEGK
            340       350       360       370       380       390  

              280       290       300       310       320       330
pF1KB7 KKGGGEGGAGADEEKEQSHRPFLMLQARQSEDHPHRRRRRGLECDGKVNICCKKQFFVSF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KKGGGEGGAGADEEKEQSHRPFLMLQARQSEDHPHRRRRRGLECDGKVNICCKKQFFVSF
            400       410       420       430       440       450  

              340       350       360       370       380       390
pF1KB7 KDIGWNDWIIAPSGYHANYCEGECPSHIAGTSGSSLSFHSTVINHYRMRGHSPFANLKSC
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KDIGWNDWIIAPSGYHANYCEGECPSHIAGTSGSSLSFHSTVINHYRMRGHSPFANLKSC
            460       470       480       490       500       510  

              400       410       420      
pF1KB7 CVPTKLRPMSMLYYDDGQNIIKKDIQNMIVEECGCS
       ::::::::::::::::::::::::::::::::::::
XP_016 CVPTKLRPMSMLYYDDGQNIIKKDIQNMIVEECGCS
            520       530       540        

>>NP_002184 (OMIM: 147390) inhibin beta B chain prepropr  (407 aa)
 initn: 1151 init1: 437 opt: 700  Z-score: 766.7  bits: 150.9 E(85289): 5.7e-36
Smith-Waterman score: 1131; 43.3% identity (69.7% similar) in 413 aa overlap (22-426:43-407)

                        10        20        30        40        50 
pF1KB7          MPLLWLRGFLLASCWIIVRSSPTPGSEGHSAAPDCPSCALAALPKDVPNSQ
                                     : ::: : :    : ::.    :...   .
NP_002 CLLLLAAGWLGPEAWGSPTPPPTPAAPPPPPPPGSPGGSQ-DTCTSCGGFRRPEELGRVD
             20        30        40        50         60        70 

              60        70        80        90       100       110 
pF1KB7 PEMVEAVKKHILNMLHLKKRPDVTQPVPKAALLNAIRKLHVGKVGENGYVEIEDDIGRRA
        ...::::.:::. :... ::..:. :::::...:.::::.::: :.: :::    :. .
NP_002 GDFLEAVKRHILSRLQMRGRPNITHAVPKAAMVTALRKLHAGKVREDGRVEIPHLDGHAS
              80        90       100       110       120       130 

             120          130       140       150       160        
pF1KB7 EMNELMEQTSEIITFAES---GTARKTLHFEISKEGSDLSVVERAEVWLFLKV-P----K
          . .:..::::.:::.   ...:  :.: ::.::..   : .: .::.::. :    :
NP_002 PGADGQERVSEIISFAETDGLASSRVRLYFFISNEGNQNLFVVQASLWLYLKLLPYVLEK
             140       150       160       170       180       190 

           170       180       190       200       210       220   
pF1KB7 ANRTRTKVTIRLFQQQKHPQGSLDTGEEAEEVGLKGERSELLLSEKVVDARKSTWHVFPV
       ..: ...: .  ::.: :                 :.: ...  :: :: ..: ::.::.
NP_002 GSRRKVRVKVY-FQEQGH-----------------GDRWNMV--EKRVDLKRSGWHTFPL
             200                         210         220       230 

           230       240       250       260       270       280   
pF1KB7 SSSIQRLLDQGKSSLDVRIACEQCQESGASLVLLGKKKKKEEEGEGKKKGGGEGGAGADE
       . .:: :...:.  :.. . :..::: ..  :..       . ::               
NP_002 TEAIQALFERGERRLNLDVQCDSCQELAVVPVFV-------DPGE---------------
             240       250       260                               

           290       300       310       320       330       340   
pF1KB7 EKEQSHRPFLMLQARQSEDHPHRRRRRGLECDGKVNICCKKQFFVSFKDIGWNDWIIAPS
          .:::::...::: . :  :: :.:::::::..:.::..:::..:. ::::::::::.
NP_002 ---ESHRPFVVVQARLG-DSRHRIRKRGLECDGRTNLCCRQQFFIDFRLIGWNDWIIAPT
        270       280        290       300       310       320     

           350       360       370       380       390       400   
pF1KB7 GYHANYCEGECPSHIAGTSGSSLSFHSTVINHYRMRGHSPFANLKSCCVPTKLRPMSMLY
       ::..::::: ::...::. ::. :::..:.:.::::: .: ....:::.::::  :::::
NP_002 GYYGNYCEGSCPAYLAGVPGSASSFHTAVVNQYRMRGLNP-GTVNSCCIPTKLSTMSMLY
         330       340       350       360        370       380    

           410       420      
pF1KB7 YDDGQNIIKKDIQNMIVEECGCS
       .::  ::.:.:. :::::::::.
NP_002 FDDEYNIVKRDVPNMIVEECGCA
          390       400       

>>NP_005529 (OMIM: 601233) inhibin beta C chain prepropr  (352 aa)
 initn: 684 init1: 501 opt: 523  Z-score: 574.4  bits: 115.1 E(85289): 3e-25
Smith-Waterman score: 679; 32.6% identity (56.0% similar) in 423 aa overlap (9-426:5-352)

               10        20        30        40        50        60
pF1KB7 MPLLWLRGFLLASCWIIVRSSPTPGSEGHSAAPDCPSCALAALPKDVPNSQPEMVEAVKK
               .:::   .   .  :: . :.     ::.:.  .:  .. ...  ... .:.
NP_005     MTSSLLLAFLLLAPTTVATPRAGGQ-----CPACGGPTL--ELESQRELLLDLAKR
                   10        20             30          40         

               70        80        90       100       110       120
pF1KB7 HILNMLHLKKRPDVTQPVPKAALLNAIRKLHVGKVGENGYVEIEDDIGRRAEMNELMEQT
        ::. ::: .:: ...:: .::: .:...::    :    . .::.           :: 
NP_005 SILDKLHLTQRPTLNRPVSRAALRTALQHLH----GVPQGALLEDN----------REQE
      50        60        70        80            90               

              130            140       150       160       170     
pF1KB7 SEIITFAESGTA-----RKTLHFEISKEGSDLSVVERAEVWLFLKVPKANRTRTKVTIRL
        :::.:::.: .     :  .::  .. ..:  : ..: . .:...:. .    :: .  
NP_005 CEIISFAETGLSTINQTRLDFHFSSDRTAGDREV-QQASLMFFVQLPSNTTWTLKVRV--
         100       110       120        130       140       150    

         180       190       200       210       220       230     
pF1KB7 FQQQKHPQGSLDTGEEAEEVGLKGERSELLLSEKVVDARKSTWHVFPVSSSIQRLLDQGK
                 :  : .  .. :    .. ::    :::  : :: .:..   :   .::.
NP_005 ----------LVLGPHNTNLTLA---TQYLLE---VDA--SGWHQLPLGPEAQAACSQGH
                      160          170            180       190    

         240       250       260       270       280       290     
pF1KB7 SSLDVRIACEQCQESGASLVLLGKKKKKEEEGEGKKKGGGEGGAGADEEKEQSHRPFLML
        .:.. .   . : . .:..:                    :::        .::::.  
NP_005 LTLELVL---EGQVAQSSVIL--------------------GGA--------AHRPFV--
          200          210                                   220   

         300       310       320       330       340       350     
pF1KB7 QARQSEDHPHRRRRRGLECDGKVNICCKKQFFVSFKDIGWNDWIIAPSGYHANYCEGECP
        ::      :. .:::..:.:   .::...:::.:..:::.:::: : ::  :.: :.::
NP_005 AARVRVGGKHQIHRRGIDCQGGSRMCCRQEFFVDFREIGWHDWIIQPEGYAMNFCIGQCP
             230       240       250       260       270       280 

         360       370       380       390       400       410     
pF1KB7 SHIAGTSGSSLSFHSTVINHYRMRGHSPFANLKSCCVPTKLRPMSMLYYDDGQNIIKKDI
        ::::  : . :::..:.:  .    .  ..  ::::::  ::.:.::::  .::.: ::
NP_005 LHIAGMPGIAASFHTAVLNLLKANTAAGTTGGGSCCVPTARRPLSLLYYDRDSNIVKTDI
             290       300       310       320       330       340 

         420      
pF1KB7 QNMIVEECGCS
        .:.:: ::::
NP_005 PDMVVEACGCS
             350  

>>NP_113667 (OMIM: 612031) inhibin beta E chain prepropr  (350 aa)
 initn: 661 init1: 317 opt: 500  Z-score: 549.3  bits: 110.4 E(85289): 7.4e-24
Smith-Waterman score: 612; 32.0% identity (55.8% similar) in 425 aa overlap (4-426:8-350)

                   10        20        30        40        50      
pF1KB7     MPLLWLRGFLLASCWIIVRSSPTPGSEGHSAAPDCPSCALAALPKDVPNSQPEMV-
              :::   ::   : .::.. : ::        ::::. . :   .:...  .: 
NP_113 MRLPDVQLWL--VLL---WALVRAQGT-GSV-------CPSCGGSKL---APQAERALVL
               10             20                30           40    

          60        70        80        90        100       110    
pF1KB7 EAVKKHILNMLHLKKRPDVTQPVPKAALLNAIRKLHVGKVGE-NGYVEIEDDIGRRAEMN
       : .:..::. ::: .:: .:.: :.:::  :.:.:. :.:.  ::     ...   : ..
NP_113 ELAKQQILDGLHLTSRPRITHPPPQAALTRALRRLQPGSVAPGNG-----EEVISFATVT
           50        60        70        80             90         

          120       130       140       150       160       170    
pF1KB7 ELMEQTSEIITFAESGTARKTLHFEISKEGSDLSVVERAEVWLFLKVPKANRTRTKVTIR
       .     : ..::  : : :.  :            . .:..:: . .:    :   . .:
NP_113 DSTSAYSSLLTFHLS-TPRS--HH-----------LYHARLWLHV-LPTLPGT---LCLR
     100       110          120                  130           140 

          180       190       200       210       220       230    
pF1KB7 LFQQQKHPQGSLDTGEEAEEVGLKGERSELLLSEKVVDARKSTWHVFPVSSSIQRLLDQG
       .:.           : . .. :     :. ::.:. .   .  ::.. . ::  :   .:
NP_113 IFRW----------GPRRRRQG-----SRTLLAEHHIT--NLGWHTLTLPSSGLRGEKSG
                       150            160         170       180    

          240       250       260       270       280       290    
pF1KB7 KSSLDVRIACEQCQESGASLVLLGKKKKKEEEGEGKKKGGGEGGAGADEEKEQSHRPFLM
          : ... :.  .  : : :  :. ..  .             ::        ..::: 
NP_113 --VLKLQLDCRPLE--GNSTVT-GQPRRLLDT------------AG-------HQQPFLE
            190         200        210                          220

          300       310       320       330       340       350    
pF1KB7 LQARQSEDHPHRRRRRGLECDGKVNICCKKQFFVSFKDIGWNDWIIAPSGYHANYCEGEC
       :. : .:    : :::   :.  . .::... .:.:...:: :::. : ::. ::: :.:
NP_113 LKIRANEPGAGRARRRTPTCEPATPLCCRRDHYVDFQELGWRDWILQPEGYQLNYCSGQC
              230       240       250       260       270       280

          360       370       380       390       400       410    
pF1KB7 PSHIAGTSGSSLSFHSTVINHYRMRGHSPFANLKSCCVPTKLRPMSMLYYDDGQNIIKKD
       : :.::. : . ::::.:..   .....:.    ::::::  ::.:.:: : . :..: :
NP_113 PPHLAGSPGIAASFHSAVFS--LLKANNPWPASTSCCVPTARRPLSLLYLDHNGNVVKTD
              290       300         310       320       330        

          420      
pF1KB7 IQNMIVEECGCS
       . .:.:: ::::
NP_113 VPDMVVEACGCS
      340       350

>>XP_011527625 (OMIM: 112261,112600,235200) PREDICTED: b  (240 aa)
 initn: 400 init1: 203 opt: 393  Z-score: 434.8  bits: 88.7 E(85289): 1.8e-17
Smith-Waterman score: 417; 31.0% identity (62.8% similar) in 226 aa overlap (205-425:35-239)

          180       190       200       210       220       230    
pF1KB7 LFQQQKHPQGSLDTGEEAEEVGLKGERSELLLSEKVVDARKSTWHVFPVSSSIQRLLDQG
                                     ::. ..:.   : :. : :. ...:   ::
XP_011 LGNNSSFHHRINIYEIIKPATANSKFPVTRLLDTRLVNQNASRWESFDVTPAVMRWTAQG
           10        20        30        40        50        60    

          240       250       260       270       280       290    
pF1KB7 KSSLDVRIACEQCQESGASLVLLGKKKKKEEEGEGKKKGGGEGGAGADEEKEQSHRPFLM
       ...    .   . .:               ..: .:..     .   ::.. .. ::.:.
XP_011 HANHGFVVEVAHLEE---------------KQGVSKRHVRISRSLHQDEHSWSQIRPLLV
           70                       80        90       100         

          300        310       320          330       340       350
pF1KB7 LQARQSEDHP-HRRRRRGLECDGKVNI--CCKKQ-FFVSFKDIGWNDWIIAPSGYHANYC
         ..... :: :.:..:  .   .  .   ::.. ..:.:.:.::::::.:: :::: ::
XP_011 TFGHDGKGHPLHKREKRQAKHKQRKRLKSSCKRHPLYVDFSDVGWNDWIVAPPGYHAFYC
     110       120       130       140       150       160         

              360        370       380       390       400         
pF1KB7 EGECPSHIAG-TSGSSLSFHSTVINHYRMRGHSPFANLKSCCVPTKLRPMSMLYYDDGQN
       .::::  .:   .... .. .:..:   . .. :    :.:::::.:  .:::: :....
XP_011 HGECPFPLADHLNSTNHAIVQTLVN--SVNSKIP----KACCVPTELSAISMLYLDENEK
     170       180       190         200           210       220   

     410       420      
pF1KB7 IIKKDIQNMIVEECGCS
       .. :. :.:.:: ::: 
XP_011 VVLKNYQDMVVEGCGCR
           230       240

>>NP_001191 (OMIM: 112261,112600,235200) bone morphogene  (396 aa)
 initn: 423 init1: 203 opt: 393  Z-score: 431.8  bits: 88.8 E(85289): 2.6e-17
Smith-Waterman score: 458; 26.8% identity (56.7% similar) in 406 aa overlap (33-425:26-395)

             10        20        30        40        50          60
pF1KB7 LLWLRGFLLASCWIIVRSSPTPGSEGHSAAPDCPSCALAALPKDVPNSQP--EMVEAVKK
                                     :.     .::  .  :.:::  :..   . 
NP_001      MVAGTRCLLALLLPQVLLGGAAGLVPELGRRKFAAASSGRPSSQPSDEVLSEFEL
                    10        20        30        40        50     

               70          80        90       100       110        
pF1KB7 HILNMLHLKKRPDVTQP--VPKAALLNAIRKLHVGKVGENGYVEIEDDIGRRAEMNELME
       ..:.:. ::.::  ..   ::   .:.  :. : :. :  .  .  .  . ::.  . ..
NP_001 RLLSMFGLKQRPTPSRDAVVPPY-MLDLYRR-HSGQPGSPAPDHRLERAASRANTVRSFH
          60        70         80         90       100       110   

      120        130       140       150          160       170    
pF1KB7 QTSEIITFAE-SGTARKTLHFEISKEGSDLSVVERAEVWLF---LKVPKANRTRTKVTIR
       .   .  . : :: . . . :..:.  ..   .  ::. .:   ..   .: .  .  : 
NP_001 HEESLEELPETSGKTTRRFFFNLSSIPTE-EFITSAELQVFREQMQDALGNNSSFHHRIN
           120       130       140        150       160       170  

          180       190       200       210       220       230    
pF1KB7 LFQQQKHPQGSLDTGEEAEEVGLKGERSELLLSEKVVDARKSTWHVFPVSSSIQRLLDQG
       ...  : :     :..    :         ::. ..:.   : :. : :. ...:   ::
NP_001 IYEIIK-PA----TANSKFPV-------TRLLDTRLVNQNASRWESFDVTPAVMRWTAQG
             180                  190       200       210       220

          240       250       260       270       280       290    
pF1KB7 KSSLDVRIACEQCQESGASLVLLGKKKKKEEEGEGKKKGGGEGGAGADEEKEQSHRPFLM
       ...    .         : :        .:..: .:..     .   ::.. .. ::.:.
NP_001 HANHGFVVEV-------AHL--------EEKQGVSKRHVRISRSLHQDEHSWSQIRPLLV
              230                      240       250       260     

          300        310       320          330       340       350
pF1KB7 LQARQSEDHP-HRRRRRGLECDGKVNI--CCKKQ-FFVSFKDIGWNDWIIAPSGYHANYC
         ..... :: :.:..:  .   .  .   ::.. ..:.:.:.::::::.:: :::: ::
NP_001 TFGHDGKGHPLHKREKRQAKHKQRKRLKSSCKRHPLYVDFSDVGWNDWIVAPPGYHAFYC
         270       280       290       300       310       320     

              360        370       380       390       400         
pF1KB7 EGECPSHIAG-TSGSSLSFHSTVINHYRMRGHSPFANLKSCCVPTKLRPMSMLYYDDGQN
       .::::  .:   .... .. .:..:   . .. :    :.:::::.:  .:::: :....
NP_001 HGECPFPLADHLNSTNHAIVQTLVNS--VNSKIP----KACCVPTELSAISMLYLDENEK
         330       340       350             360       370         

     410       420      
pF1KB7 IIKKDIQNMIVEECGCS
       .. :. :.:.:: ::: 
NP_001 VVLKNYQDMVVEGCGCR
     380       390      

>>NP_065685 (OMIM: 606522,613702,613703,613704) growth/d  (364 aa)
 initn: 416 init1: 211 opt: 380  Z-score: 418.1  bits: 86.2 E(85289): 1.5e-16
Smith-Waterman score: 380; 38.5% identity (68.5% similar) in 143 aa overlap (289-425:230-363)

      260       270       280       290       300       310        
pF1KB7 KKKKKEEEGEGKKKGGGEGGAGADEEKEQSHRPFLMLQARQSEDHPHRRRRRG-----LE
                                     :  .:..    .. :: :.:: .     : 
NP_065 LFLEILVKEDRDSGVNFQPEDTCARLRCSLHASLLVVTLNPDQCHPSRKRRAAIPVPKLS
     200       210       220       230       240       250         

           320       330       340       350        360       370  
pF1KB7 CDGKVNICCKKQFFVSFKDIGWNDWIIAPSGYHANYCEGECP-SHIAGTSGSSLSFHSTV
       :    :.: ..:.:..:.:.::. :::::.:. ::::.:::: :   . ..:. .: ...
NP_065 CK---NLCHRHQLFINFRDLGWHKWIIAPKGFMANYCHGECPFSLTISLNSSNYAFMQAL
     260          270       280       290       300       310      

            380       390       400       410       420      
pF1KB7 INHYRMRGHSPFANLKSCCVPTKLRPMSMLYYDDGQNIIKKDIQNMIVEECGCS
            :.. .:    .. :.:::: :.:::: :...:.: .  ..:.:.:::: 
NP_065 -----MHAVDPEIP-QAVCIPTKLSPISMLYQDNNDNVILRHYEDMVVDECGCG
             320        330       340       350       360    




426 residues in 1 query   sequences
60827320 residues in 85289 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Fri Nov  4 04:08:59 2016 done: Fri Nov  4 04:09:00 2016
 Total Scan time:  8.420 Total Display time:  0.020

Function used was FASTA [36.3.4 Apr, 2011]
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