Result of FASTA (omim) for pF1KB5574
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KB5574, 212 aa
  1>>>pF1KB5574 212 - 212 aa - 212 aa
Library: /omim/omim.rfq.tfa
  60827320 residues in 85289 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 5.1653+/-0.00036; mu= 14.1273+/- 0.022
 mean_var=60.7347+/-13.045, 0's: 0 Z-trim(113.8): 65  B-trim: 2060 in 2/52
 Lambda= 0.164572
 statistics sampled from 23261 (23349) to 23261 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.654), E-opt: 0.2 (0.274), width:  16
 Scan time:  6.270

The best scores are:                                      opt bits E(85289)
NP_115904 (OMIM: 605404) bcl-2-related ovarian kil ( 212) 1399 340.4 1.3e-93
XP_011509998 (OMIM: 605404) PREDICTED: bcl-2-relat ( 212) 1399 340.4 1.3e-93
XP_016860264 (OMIM: 605404) PREDICTED: bcl-2-relat ( 134)  899 221.6 4.8e-58
XP_016860265 (OMIM: 605404) PREDICTED: bcl-2-relat ( 134)  899 221.6 4.8e-58
XP_011509999 (OMIM: 605404) PREDICTED: bcl-2-relat ( 117)  740 183.8 9.9e-47
NP_001278357 (OMIM: 600040) apoptosis regulator BA ( 221)  208 57.6 1.8e-08
NP_004315 (OMIM: 600040) apoptosis regulator BAX i ( 218)  205 56.9 2.9e-08
NP_620119 (OMIM: 600040) apoptosis regulator BAX i ( 179)  200 55.7 5.6e-08
NP_620116 (OMIM: 600040) apoptosis regulator BAX i ( 192)  199 55.5   7e-08
XP_016882566 (OMIM: 600040) PREDICTED: apoptosis r ( 173)  187 52.6 4.6e-07
NP_001278358 (OMIM: 600040) apoptosis regulator BA ( 181)  186 52.4 5.7e-07
NP_001309171 (OMIM: 600039) bcl-2-like protein 1 i ( 233)  182 51.5 1.4e-06
NP_001304850 (OMIM: 600039) bcl-2-like protein 1 i ( 233)  182 51.5 1.4e-06
NP_001309168 (OMIM: 600039) bcl-2-like protein 1 i ( 233)  182 51.5 1.4e-06
XP_011527266 (OMIM: 600039) PREDICTED: bcl-2-like  ( 233)  182 51.5 1.4e-06
NP_001304849 (OMIM: 600039) bcl-2-like protein 1 i ( 233)  182 51.5 1.4e-06
NP_612815 (OMIM: 600039) bcl-2-like protein 1 isof ( 233)  182 51.5 1.4e-06
NP_001309169 (OMIM: 600039) bcl-2-like protein 1 i ( 233)  182 51.5 1.4e-06
XP_016883482 (OMIM: 600039) PREDICTED: bcl-2-like  ( 233)  182 51.5 1.4e-06
NP_001304848 (OMIM: 600039) bcl-2-like protein 1 i ( 233)  182 51.5 1.4e-06
NP_001186768 (OMIM: 601931) bcl-2-like protein 2 [ ( 193)  175 49.8 3.7e-06
NP_004041 (OMIM: 601931) bcl-2-like protein 2 [Hom ( 193)  175 49.8 3.7e-06
NP_001179 (OMIM: 600516) bcl-2 homologous antagoni ( 211)  170 48.6   9e-06
XP_011513081 (OMIM: 600516) PREDICTED: bcl-2 homol ( 211)  170 48.6   9e-06
XP_011513082 (OMIM: 600516) PREDICTED: bcl-2 homol ( 152)  162 46.6 2.5e-05
NP_000648 (OMIM: 151430) apoptosis regulator Bcl-2 ( 205)  161 46.5 3.8e-05
NP_000624 (OMIM: 151430) apoptosis regulator Bcl-2 ( 239)  160 46.2 5.2e-05
XP_011524437 (OMIM: 151430) PREDICTED: apoptosis r ( 224)  158 45.8 6.8e-05
NP_001184249 (OMIM: 159552) induced myeloid leukem ( 197)  157 45.5 7.2e-05
XP_016881406 (OMIM: 151430) PREDICTED: apoptosis r ( 198)  157 45.5 7.2e-05
NP_001278359 (OMIM: 600040) apoptosis regulator BA ( 140)  155 44.9 7.5e-05
NP_001278360 (OMIM: 600040) apoptosis regulator BA ( 114)  149 43.5 0.00017
NP_620118 (OMIM: 600040) apoptosis regulator BAX i ( 143)  149 43.5  0.0002
NP_068779 (OMIM: 159552) induced myeloid leukemia  ( 350)  147 43.2 0.00061


>>NP_115904 (OMIM: 605404) bcl-2-related ovarian killer   (212 aa)
 initn: 1399 init1: 1399 opt: 1399  Z-score: 1801.6  bits: 340.4 E(85289): 1.3e-93
Smith-Waterman score: 1399; 100.0% identity (100.0% similar) in 212 aa overlap (1-212:1-212)

               10        20        30        40        50        60
pF1KB5 MEVLRRSSVFAAEIMDAFDRSPTDKELVAQAKALGREYVHARLLRAGLSWSAPERAAPVP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_115 MEVLRRSSVFAAEIMDAFDRSPTDKELVAQAKALGREYVHARLLRAGLSWSAPERAAPVP
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB5 GRLAEVCAVLLRLGDELEMIRPSVYRNVARQLHISLQSEPVVTDAFLAVAGHIFSAGITW
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_115 GRLAEVCAVLLRLGDELEMIRPSVYRNVARQLHISLQSEPVVTDAFLAVAGHIFSAGITW
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB5 GKVVSLYAVAAGLAVDCVRQAQPAMVHALVDCLGEFVRKTLATWLRRRGGWTDVLKCVVS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_115 GKVVSLYAVAAGLAVDCVRQAQPAMVHALVDCLGEFVRKTLATWLRRRGGWTDVLKCVVS
              130       140       150       160       170       180

              190       200       210  
pF1KB5 TDPGLRSHWLVAALCSFGRFLKAAFFVLLPER
       ::::::::::::::::::::::::::::::::
NP_115 TDPGLRSHWLVAALCSFGRFLKAAFFVLLPER
              190       200       210  

>>XP_011509998 (OMIM: 605404) PREDICTED: bcl-2-related o  (212 aa)
 initn: 1399 init1: 1399 opt: 1399  Z-score: 1801.6  bits: 340.4 E(85289): 1.3e-93
Smith-Waterman score: 1399; 100.0% identity (100.0% similar) in 212 aa overlap (1-212:1-212)

               10        20        30        40        50        60
pF1KB5 MEVLRRSSVFAAEIMDAFDRSPTDKELVAQAKALGREYVHARLLRAGLSWSAPERAAPVP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MEVLRRSSVFAAEIMDAFDRSPTDKELVAQAKALGREYVHARLLRAGLSWSAPERAAPVP
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB5 GRLAEVCAVLLRLGDELEMIRPSVYRNVARQLHISLQSEPVVTDAFLAVAGHIFSAGITW
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GRLAEVCAVLLRLGDELEMIRPSVYRNVARQLHISLQSEPVVTDAFLAVAGHIFSAGITW
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB5 GKVVSLYAVAAGLAVDCVRQAQPAMVHALVDCLGEFVRKTLATWLRRRGGWTDVLKCVVS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GKVVSLYAVAAGLAVDCVRQAQPAMVHALVDCLGEFVRKTLATWLRRRGGWTDVLKCVVS
              130       140       150       160       170       180

              190       200       210  
pF1KB5 TDPGLRSHWLVAALCSFGRFLKAAFFVLLPER
       ::::::::::::::::::::::::::::::::
XP_011 TDPGLRSHWLVAALCSFGRFLKAAFFVLLPER
              190       200       210  

>>XP_016860264 (OMIM: 605404) PREDICTED: bcl-2-related o  (134 aa)
 initn: 899 init1: 899 opt: 899  Z-score: 1163.1  bits: 221.6 E(85289): 4.8e-58
Smith-Waterman score: 899; 100.0% identity (100.0% similar) in 134 aa overlap (79-212:1-134)

       50        60        70        80        90       100        
pF1KB5 SWSAPERAAPVPGRLAEVCAVLLRLGDELEMIRPSVYRNVARQLHISLQSEPVVTDAFLA
                                     ::::::::::::::::::::::::::::::
XP_016                               MIRPSVYRNVARQLHISLQSEPVVTDAFLA
                                             10        20        30

      110       120       130       140       150       160        
pF1KB5 VAGHIFSAGITWGKVVSLYAVAAGLAVDCVRQAQPAMVHALVDCLGEFVRKTLATWLRRR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VAGHIFSAGITWGKVVSLYAVAAGLAVDCVRQAQPAMVHALVDCLGEFVRKTLATWLRRR
               40        50        60        70        80        90

      170       180       190       200       210  
pF1KB5 GGWTDVLKCVVSTDPGLRSHWLVAALCSFGRFLKAAFFVLLPER
       ::::::::::::::::::::::::::::::::::::::::::::
XP_016 GGWTDVLKCVVSTDPGLRSHWLVAALCSFGRFLKAAFFVLLPER
              100       110       120       130    

>>XP_016860265 (OMIM: 605404) PREDICTED: bcl-2-related o  (134 aa)
 initn: 899 init1: 899 opt: 899  Z-score: 1163.1  bits: 221.6 E(85289): 4.8e-58
Smith-Waterman score: 899; 100.0% identity (100.0% similar) in 134 aa overlap (79-212:1-134)

       50        60        70        80        90       100        
pF1KB5 SWSAPERAAPVPGRLAEVCAVLLRLGDELEMIRPSVYRNVARQLHISLQSEPVVTDAFLA
                                     ::::::::::::::::::::::::::::::
XP_016                               MIRPSVYRNVARQLHISLQSEPVVTDAFLA
                                             10        20        30

      110       120       130       140       150       160        
pF1KB5 VAGHIFSAGITWGKVVSLYAVAAGLAVDCVRQAQPAMVHALVDCLGEFVRKTLATWLRRR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VAGHIFSAGITWGKVVSLYAVAAGLAVDCVRQAQPAMVHALVDCLGEFVRKTLATWLRRR
               40        50        60        70        80        90

      170       180       190       200       210  
pF1KB5 GGWTDVLKCVVSTDPGLRSHWLVAALCSFGRFLKAAFFVLLPER
       ::::::::::::::::::::::::::::::::::::::::::::
XP_016 GGWTDVLKCVVSTDPGLRSHWLVAALCSFGRFLKAAFFVLLPER
              100       110       120       130    

>>XP_011509999 (OMIM: 605404) PREDICTED: bcl-2-related o  (117 aa)
 initn: 740 init1: 740 opt: 740  Z-score: 959.9  bits: 183.8 E(85289): 9.9e-47
Smith-Waterman score: 740; 100.0% identity (100.0% similar) in 116 aa overlap (1-116:1-116)

               10        20        30        40        50        60
pF1KB5 MEVLRRSSVFAAEIMDAFDRSPTDKELVAQAKALGREYVHARLLRAGLSWSAPERAAPVP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MEVLRRSSVFAAEIMDAFDRSPTDKELVAQAKALGREYVHARLLRAGLSWSAPERAAPVP
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB5 GRLAEVCAVLLRLGDELEMIRPSVYRNVARQLHISLQSEPVVTDAFLAVAGHIFSAGITW
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::    
XP_011 GRLAEVCAVLLRLGDELEMIRPSVYRNVARQLHISLQSEPVVTDAFLAVAGHIFSAD   
               70        80        90       100       110          

              130       140       150       160       170       180
pF1KB5 GKVVSLYAVAAGLAVDCVRQAQPAMVHALVDCLGEFVRKTLATWLRRRGGWTDVLKCVVS

>>NP_001278357 (OMIM: 600040) apoptosis regulator BAX is  (221 aa)
 initn: 153 init1: 118 opt: 208  Z-score: 273.1  bits: 57.6 E(85289): 1.8e-08
Smith-Waterman score: 208; 29.1% identity (57.0% similar) in 172 aa overlap (22-184:13-175)

               10        20        30         40        50         
pF1KB5 MEVLRRSSVFAAEIMDAFDRSPTDKELVAQAKALGRE-YVHARLLRAGLSWSAPERAA-P
                            ::..: . .. ::  . ... :  : :    ::: :  :
NP_001          MDGSGEQPRGGGPTSSEQIMKTGALLLQGFIQDRAGRMG--GEAPELALDP
                        10        20        30          40         

       60          70        80        90       100       110      
pF1KB5 VP--GRLAEVCAVLLRLGDELEMIRPSVYRNVARQLHISLQSEPVVTDAFLAVAGHIFSA
       ::  .   ..   : :.::::.        :.  :  :.  .     ..:. ::. .:: 
NP_001 VPQDASTKKLSECLKRIGDELD-------SNMELQRMIAAVDTDSPREVFFRVAADMFSD
      50        60        70               80        90       100  

         120       130       140       150       160       170     
pF1KB5 G-ITWGKVVSLYAVAAGLAVDCVRQAQPAMVHALVDCLGEFVRKTLATWLRRRGGW----
       : ..::.::.:.  :. :..  .    : ......    .:.:. :  :.. .:::    
NP_001 GNFNWGRVVALFYFASKLVLKALCTKVPELIRTIMGWTLDFLRERLLGWIQDQGGWGLPL
            110       120       130       140       150       160  

             180       190       200       210                    
pF1KB5 TDVLKCVVSTDPGLRSHWLVAALCSFGRFLKAAFFVLLPER                  
       .. :: ..: .::                                              
NP_001 AESLKRLMSLSPGRPPLLLWDAHVADRDHLCGGSAHRLTHHLEEDGLRPPAALDCVFPP
            170       180       190       200       210       220 

>>NP_004315 (OMIM: 600040) apoptosis regulator BAX isofo  (218 aa)
 initn: 146 init1: 128 opt: 205  Z-score: 269.3  bits: 56.9 E(85289): 2.9e-08
Smith-Waterman score: 205; 29.4% identity (57.5% similar) in 160 aa overlap (22-176:13-163)

               10        20        30         40        50         
pF1KB5 MEVLRRSSVFAAEIMDAFDRSPTDKELVAQAKALGRE-YVHARLLRAGLSWSAPERAA-P
                            ::..: . .. ::  . ... :  : :    ::: :  :
NP_004          MDGSGEQPRGGGPTSSEQIMKTGALLLQGFIQDRAGRMG--GEAPELALDP
                        10        20        30          40         

       60          70        80        90       100       110      
pF1KB5 VP--GRLAEVCAVLLRLGDELEMIRPSVYRNVARQLHISLQSEPVVTDAFLAVAGHIFSA
       ::  .   ..   : :.::::.        :.  :  :.  .     ..:. ::. .:: 
NP_004 VPQDASTKKLSECLKRIGDELD-------SNMELQRMIAAVDTDSPREVFFRVAADMFSD
      50        60        70               80        90       100  

         120       130       140       150       160       170     
pF1KB5 G-ITWGKVVSLYAVAAGLAVDCVRQAQPAMVHALVDCLGEFVRKTLATWLRRRGGWTDVL
       : ..::.::.:.  :. :..  .    : ......    .:.:. :  :.. .:::. .:
NP_004 GNFNWGRVVALFYFASKLVLKALCTKVPELIRTIMGWTLDFLRERLLGWIQDQGGWVRLL
            110       120       130       140       150       160  

         180       190       200       210                     
pF1KB5 KCVVSTDPGLRSHWLVAALCSFGRFLKAAFFVLLPER                   
       :                                                       
NP_004 KPPHPHHRALTTAPAPPSLPPATPLGPWAFWSRSQWCPLPIFRSSDVVYNAFSLRV
            170       180       190       200       210        

>>NP_620119 (OMIM: 600040) apoptosis regulator BAX isofo  (179 aa)
 initn: 156 init1: 123 opt: 200  Z-score: 264.2  bits: 55.7 E(85289): 5.6e-08
Smith-Waterman score: 200; 29.5% identity (57.1% similar) in 156 aa overlap (22-172:13-159)

               10        20        30         40        50         
pF1KB5 MEVLRRSSVFAAEIMDAFDRSPTDKELVAQAKALGRE-YVHARLLRAGLSWSAPERAA-P
                            ::..: . .. ::  . ... :  : :    ::: :  :
NP_620          MDGSGEQPRGGGPTSSEQIMKTGALLLQGFIQDRAGRMG--GEAPELALDP
                        10        20        30          40         

       60          70        80        90       100       110      
pF1KB5 VP--GRLAEVCAVLLRLGDELEMIRPSVYRNVARQLHISLQSEPVVTDAFLAVAGHIFSA
       ::  .   ..   : :.::::.        :.  :  :.  .     ..:. ::. .:: 
NP_620 VPQDASTKKLSECLKRIGDELD-------SNMELQRMIAAVDTDSPREVFFRVAADMFSD
      50        60        70               80        90       100  

         120       130       140       150       160       170     
pF1KB5 G-ITWGKVVSLYAVAAGLAVDCVRQAQPAMVHALVDCLGEFVRKTLATWLRRRGGWTDVL
       : ..::.::.:.  :. :..  .    : ......    .:.:. :  :.. .::::   
NP_620 GNFNWGRVVALFYFASKLVLKALCTKVPELIRTIMGWTLDFLRERLLGWIQDQGGWTVTI
            110       120       130       140       150       160  

         180       190       200       210  
pF1KB5 KCVVSTDPGLRSHWLVAALCSFGRFLKAAFFVLLPER
                                            
NP_620 FVAGVLTASLTIWKKMG                    
            170                             

>>NP_620116 (OMIM: 600040) apoptosis regulator BAX isofo  (192 aa)
 initn: 155 init1: 122 opt: 199  Z-score: 262.5  bits: 55.5 E(85289): 7e-08
Smith-Waterman score: 199; 28.9% identity (56.6% similar) in 159 aa overlap (22-175:13-162)

               10        20        30         40        50         
pF1KB5 MEVLRRSSVFAAEIMDAFDRSPTDKELVAQAKALGRE-YVHARLLRAGLSWSAPERAA-P
                            ::..: . .. ::  . ... :  : :    ::: :  :
NP_620          MDGSGEQPRGGGPTSSEQIMKTGALLLQGFIQDRAGRMG--GEAPELALDP
                        10        20        30          40         

       60          70        80        90       100       110      
pF1KB5 VP--GRLAEVCAVLLRLGDELEMIRPSVYRNVARQLHISLQSEPVVTDAFLAVAGHIFSA
       ::  .   ..   : :.::::.        :.  :  :.  .     ..:. ::. .:: 
NP_620 VPQDASTKKLSECLKRIGDELD-------SNMELQRMIAAVDTDSPREVFFRVAADMFSD
      50        60        70               80        90       100  

         120       130       140       150       160       170     
pF1KB5 G-ITWGKVVSLYAVAAGLAVDCVRQAQPAMVHALVDCLGEFVRKTLATWLRRRGGWTDVL
       : ..::.::.:.  :. :..  .    : ......    .:.:. :  :.. .:::  .:
NP_620 GNFNWGRVVALFYFASKLVLKALCTKVPELIRTIMGWTLDFLRERLLGWIQDQGGWDGLL
            110       120       130       140       150       160  

         180       190       200       210  
pF1KB5 KCVVSTDPGLRSHWLVAALCSFGRFLKAAFFVLLPER
                                            
NP_620 SYFGTPTWQTVTIFVAGVLTASLTIWKKMG       
            170       180       190         

>>XP_016882566 (OMIM: 600040) PREDICTED: apoptosis regul  (173 aa)
 initn: 151 init1: 122 opt: 187  Z-score: 247.8  bits: 52.6 E(85289): 4.6e-07
Smith-Waterman score: 187; 30.1% identity (57.4% similar) in 136 aa overlap (45-175:15-143)

           20        30        40         50         60          70
pF1KB5 MDAFDRSPTDKELVAQAKALGREYVHARLLRAG-LSWSAPERAA-PVP--GRLAEVCAVL
                                     ::: ..  ::: :  :::  .   ..   :
XP_016                 MKTGALLLQGFIQDRAGRMGGEAPELALDPVPQDASTKKLSECL
                               10        20        30        40    

               80        90       100       110        120         
pF1KB5 LRLGDELEMIRPSVYRNVARQLHISLQSEPVVTDAFLAVAGHIFSAG-ITWGKVVSLYAV
        :.::::.        :.  :  :.  .     ..:. ::. .:: : ..::.::.:.  
XP_016 KRIGDELD-------SNMELQRMIAAVDTDSPREVFFRVAADMFSDGNFNWGRVVALFYF
           50               60        70        80        90       

     130       140       150       160       170       180         
pF1KB5 AAGLAVDCVRQAQPAMVHALVDCLGEFVRKTLATWLRRRGGWTDVLKCVVSTDPGLRSHW
       :. :..  .    : ......    .:.:. :  :.. .:::  .:              
XP_016 ASKLVLKALCTKVPELIRTIMGWTLDFLRERLLGWIQDQGGWDGLLSYFGTPTWQTVTIF
       100       110       120       130       140       150       

     190       200       210  
pF1KB5 LVAALCSFGRFLKAAFFVLLPER
                              
XP_016 VAGVLTASLTIWKKMG       
       160       170          




212 residues in 1 query   sequences
60827320 residues in 85289 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Fri Nov  4 03:55:52 2016 done: Fri Nov  4 03:55:53 2016
 Total Scan time:  6.270 Total Display time:  0.000

Function used was FASTA [36.3.4 Apr, 2011]
Inquiries or Suggestions ?
Send a message to flexiclone AT kazusagt.com