Result of FASTA (omim) for pF1KB5400
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KB5400, 471 aa
  1>>>pF1KB5400 471 - 471 aa - 471 aa
Library: /omim/omim.rfq.tfa
  60827320 residues in 85289 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 8.0871+/-0.000383; mu= 12.9309+/- 0.024
 mean_var=402.1619+/-83.679, 0's: 0 Z-trim(124.2): 54  B-trim: 2640 in 2/60
 Lambda= 0.063955
 statistics sampled from 45217 (45286) to 45217 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.802), E-opt: 0.2 (0.531), width:  16
 Scan time: 11.070

The best scores are:                                      opt bits E(85289)
NP_031389 (OMIM: 300084,300967) non-POU domain-con ( 471) 3200 309.0 1.8e-83
NP_001138880 (OMIM: 300084,300967) non-POU domain- ( 471) 3200 309.0 1.8e-83
NP_001138881 (OMIM: 300084,300967) non-POU domain- ( 471) 3200 309.0 1.8e-83
NP_001138882 (OMIM: 300084,300967) non-POU domain- ( 382) 2567 250.4 6.3e-66
XP_011533439 (OMIM: 612408) PREDICTED: paraspeckle ( 469) 1776 177.6 6.6e-44
XP_006719907 (OMIM: 612408) PREDICTED: paraspeckle ( 523) 1773 177.4 8.4e-44
NP_001035879 (OMIM: 612408) paraspeckle component  ( 523) 1773 177.4 8.4e-44
XP_016857543 (OMIM: 605199) PREDICTED: splicing fa ( 707) 1716 172.3 3.8e-42
XP_005271170 (OMIM: 605199) PREDICTED: splicing fa ( 707) 1716 172.3 3.8e-42
XP_005271169 (OMIM: 605199) PREDICTED: splicing fa ( 707) 1716 172.3 3.8e-42
XP_016857542 (OMIM: 605199) PREDICTED: splicing fa ( 707) 1716 172.3 3.8e-42
NP_005057 (OMIM: 605199) splicing factor, proline- ( 707) 1716 172.3 3.8e-42
XP_005271172 (OMIM: 605199) PREDICTED: splicing fa ( 669) 1696 170.4 1.3e-41
XP_011540252 (OMIM: 605199) PREDICTED: splicing fa ( 679) 1696 170.5 1.3e-41
XP_011533444 (OMIM: 612408) PREDICTED: paraspeckle ( 406) 1660 166.8   1e-40
XP_016876139 (OMIM: 612408) PREDICTED: paraspeckle ( 393) 1655 166.3 1.4e-40
XP_011533443 (OMIM: 612408) PREDICTED: paraspeckle ( 409) 1655 166.3 1.4e-40
XP_011533442 (OMIM: 612408) PREDICTED: paraspeckle ( 417) 1655 166.3 1.4e-40
XP_011533441 (OMIM: 612408) PREDICTED: paraspeckle ( 417) 1655 166.3 1.4e-40
XP_011533440 (OMIM: 612408) PREDICTED: paraspeckle ( 447) 1655 166.4 1.5e-40


>>NP_031389 (OMIM: 300084,300967) non-POU domain-contain  (471 aa)
 initn: 3200 init1: 3200 opt: 3200  Z-score: 1619.4  bits: 309.0 E(85289): 1.8e-83
Smith-Waterman score: 3200; 100.0% identity (100.0% similar) in 471 aa overlap (1-471:1-471)

               10        20        30        40        50        60
pF1KB5 MQSNKTFNLEKQNHTPRKHHQHHHQQQHHQQQQQQPPPPPIPANGQQASSQNEGLTIDLK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_031 MQSNKTFNLEKQNHTPRKHHQHHHQQQHHQQQQQQPPPPPIPANGQQASSQNEGLTIDLK
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB5 NFRKPGEKTFTQRSRLFVGNLPPDITEEEMRKLFEKYGKAGEVFIHKDKGFGFIRLETRT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_031 NFRKPGEKTFTQRSRLFVGNLPPDITEEEMRKLFEKYGKAGEVFIHKDKGFGFIRLETRT
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB5 LAEIAKVELDNMPLRGKQLRVRFACHSASLTVRNLPQYVSNELLEEAFSVFGQVERAVVI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_031 LAEIAKVELDNMPLRGKQLRVRFACHSASLTVRNLPQYVSNELLEEAFSVFGQVERAVVI
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB5 VDDRGRPSGKGIVEFSGKPAARKALDRCSEGSFLLTTFPRPVTVEPMDQLDDEEGLPEKL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_031 VDDRGRPSGKGIVEFSGKPAARKALDRCSEGSFLLTTFPRPVTVEPMDQLDDEEGLPEKL
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB5 VIKNQQFHKEREQPPRFAQPGSFEYEYAMRWKALIEMEKQQQDQVDRNIKEAREKLEMEM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_031 VIKNQQFHKEREQPPRFAQPGSFEYEYAMRWKALIEMEKQQQDQVDRNIKEAREKLEMEM
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KB5 EAARHEHQVMLMRQDLMRRQEELRRMEELHNQEVQKRKQLELRQEEERRRREEEMRRQQE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_031 EAARHEHQVMLMRQDLMRRQEELRRMEELHNQEVQKRKQLELRQEEERRRREEEMRRQQE
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KB5 EMMRRQQEGFKGTFPDAREQEIRMGQMAMGGAMGINNRGAMPPAPVPAGTPAPPGPATMM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_031 EMMRRQQEGFKGTFPDAREQEIRMGQMAMGGAMGINNRGAMPPAPVPAGTPAPPGPATMM
              370       380       390       400       410       420

              430       440       450       460       470 
pF1KB5 PDGTLGLTPPTTERFGQAATMEGIGAIGGTPPAFNRAAPGAEFAPNKRRRY
       :::::::::::::::::::::::::::::::::::::::::::::::::::
NP_031 PDGTLGLTPPTTERFGQAATMEGIGAIGGTPPAFNRAAPGAEFAPNKRRRY
              430       440       450       460       470 

>>NP_001138880 (OMIM: 300084,300967) non-POU domain-cont  (471 aa)
 initn: 3200 init1: 3200 opt: 3200  Z-score: 1619.4  bits: 309.0 E(85289): 1.8e-83
Smith-Waterman score: 3200; 100.0% identity (100.0% similar) in 471 aa overlap (1-471:1-471)

               10        20        30        40        50        60
pF1KB5 MQSNKTFNLEKQNHTPRKHHQHHHQQQHHQQQQQQPPPPPIPANGQQASSQNEGLTIDLK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MQSNKTFNLEKQNHTPRKHHQHHHQQQHHQQQQQQPPPPPIPANGQQASSQNEGLTIDLK
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB5 NFRKPGEKTFTQRSRLFVGNLPPDITEEEMRKLFEKYGKAGEVFIHKDKGFGFIRLETRT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NFRKPGEKTFTQRSRLFVGNLPPDITEEEMRKLFEKYGKAGEVFIHKDKGFGFIRLETRT
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB5 LAEIAKVELDNMPLRGKQLRVRFACHSASLTVRNLPQYVSNELLEEAFSVFGQVERAVVI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LAEIAKVELDNMPLRGKQLRVRFACHSASLTVRNLPQYVSNELLEEAFSVFGQVERAVVI
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB5 VDDRGRPSGKGIVEFSGKPAARKALDRCSEGSFLLTTFPRPVTVEPMDQLDDEEGLPEKL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VDDRGRPSGKGIVEFSGKPAARKALDRCSEGSFLLTTFPRPVTVEPMDQLDDEEGLPEKL
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB5 VIKNQQFHKEREQPPRFAQPGSFEYEYAMRWKALIEMEKQQQDQVDRNIKEAREKLEMEM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VIKNQQFHKEREQPPRFAQPGSFEYEYAMRWKALIEMEKQQQDQVDRNIKEAREKLEMEM
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KB5 EAARHEHQVMLMRQDLMRRQEELRRMEELHNQEVQKRKQLELRQEEERRRREEEMRRQQE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EAARHEHQVMLMRQDLMRRQEELRRMEELHNQEVQKRKQLELRQEEERRRREEEMRRQQE
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KB5 EMMRRQQEGFKGTFPDAREQEIRMGQMAMGGAMGINNRGAMPPAPVPAGTPAPPGPATMM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EMMRRQQEGFKGTFPDAREQEIRMGQMAMGGAMGINNRGAMPPAPVPAGTPAPPGPATMM
              370       380       390       400       410       420

              430       440       450       460       470 
pF1KB5 PDGTLGLTPPTTERFGQAATMEGIGAIGGTPPAFNRAAPGAEFAPNKRRRY
       :::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PDGTLGLTPPTTERFGQAATMEGIGAIGGTPPAFNRAAPGAEFAPNKRRRY
              430       440       450       460       470 

>>NP_001138881 (OMIM: 300084,300967) non-POU domain-cont  (471 aa)
 initn: 3200 init1: 3200 opt: 3200  Z-score: 1619.4  bits: 309.0 E(85289): 1.8e-83
Smith-Waterman score: 3200; 100.0% identity (100.0% similar) in 471 aa overlap (1-471:1-471)

               10        20        30        40        50        60
pF1KB5 MQSNKTFNLEKQNHTPRKHHQHHHQQQHHQQQQQQPPPPPIPANGQQASSQNEGLTIDLK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MQSNKTFNLEKQNHTPRKHHQHHHQQQHHQQQQQQPPPPPIPANGQQASSQNEGLTIDLK
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB5 NFRKPGEKTFTQRSRLFVGNLPPDITEEEMRKLFEKYGKAGEVFIHKDKGFGFIRLETRT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NFRKPGEKTFTQRSRLFVGNLPPDITEEEMRKLFEKYGKAGEVFIHKDKGFGFIRLETRT
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB5 LAEIAKVELDNMPLRGKQLRVRFACHSASLTVRNLPQYVSNELLEEAFSVFGQVERAVVI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LAEIAKVELDNMPLRGKQLRVRFACHSASLTVRNLPQYVSNELLEEAFSVFGQVERAVVI
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB5 VDDRGRPSGKGIVEFSGKPAARKALDRCSEGSFLLTTFPRPVTVEPMDQLDDEEGLPEKL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VDDRGRPSGKGIVEFSGKPAARKALDRCSEGSFLLTTFPRPVTVEPMDQLDDEEGLPEKL
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB5 VIKNQQFHKEREQPPRFAQPGSFEYEYAMRWKALIEMEKQQQDQVDRNIKEAREKLEMEM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VIKNQQFHKEREQPPRFAQPGSFEYEYAMRWKALIEMEKQQQDQVDRNIKEAREKLEMEM
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KB5 EAARHEHQVMLMRQDLMRRQEELRRMEELHNQEVQKRKQLELRQEEERRRREEEMRRQQE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EAARHEHQVMLMRQDLMRRQEELRRMEELHNQEVQKRKQLELRQEEERRRREEEMRRQQE
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KB5 EMMRRQQEGFKGTFPDAREQEIRMGQMAMGGAMGINNRGAMPPAPVPAGTPAPPGPATMM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EMMRRQQEGFKGTFPDAREQEIRMGQMAMGGAMGINNRGAMPPAPVPAGTPAPPGPATMM
              370       380       390       400       410       420

              430       440       450       460       470 
pF1KB5 PDGTLGLTPPTTERFGQAATMEGIGAIGGTPPAFNRAAPGAEFAPNKRRRY
       :::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PDGTLGLTPPTTERFGQAATMEGIGAIGGTPPAFNRAAPGAEFAPNKRRRY
              430       440       450       460       470 

>>NP_001138882 (OMIM: 300084,300967) non-POU domain-cont  (382 aa)
 initn: 2567 init1: 2567 opt: 2567  Z-score: 1304.6  bits: 250.4 E(85289): 6.3e-66
Smith-Waterman score: 2567; 100.0% identity (100.0% similar) in 382 aa overlap (90-471:1-382)

      60        70        80        90       100       110         
pF1KB5 KNFRKPGEKTFTQRSRLFVGNLPPDITEEEMRKLFEKYGKAGEVFIHKDKGFGFIRLETR
                                     ::::::::::::::::::::::::::::::
NP_001                               MRKLFEKYGKAGEVFIHKDKGFGFIRLETR
                                             10        20        30

     120       130       140       150       160       170         
pF1KB5 TLAEIAKVELDNMPLRGKQLRVRFACHSASLTVRNLPQYVSNELLEEAFSVFGQVERAVV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TLAEIAKVELDNMPLRGKQLRVRFACHSASLTVRNLPQYVSNELLEEAFSVFGQVERAVV
               40        50        60        70        80        90

     180       190       200       210       220       230         
pF1KB5 IVDDRGRPSGKGIVEFSGKPAARKALDRCSEGSFLLTTFPRPVTVEPMDQLDDEEGLPEK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IVDDRGRPSGKGIVEFSGKPAARKALDRCSEGSFLLTTFPRPVTVEPMDQLDDEEGLPEK
              100       110       120       130       140       150

     240       250       260       270       280       290         
pF1KB5 LVIKNQQFHKEREQPPRFAQPGSFEYEYAMRWKALIEMEKQQQDQVDRNIKEAREKLEME
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LVIKNQQFHKEREQPPRFAQPGSFEYEYAMRWKALIEMEKQQQDQVDRNIKEAREKLEME
              160       170       180       190       200       210

     300       310       320       330       340       350         
pF1KB5 MEAARHEHQVMLMRQDLMRRQEELRRMEELHNQEVQKRKQLELRQEEERRRREEEMRRQQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MEAARHEHQVMLMRQDLMRRQEELRRMEELHNQEVQKRKQLELRQEEERRRREEEMRRQQ
              220       230       240       250       260       270

     360       370       380       390       400       410         
pF1KB5 EEMMRRQQEGFKGTFPDAREQEIRMGQMAMGGAMGINNRGAMPPAPVPAGTPAPPGPATM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EEMMRRQQEGFKGTFPDAREQEIRMGQMAMGGAMGINNRGAMPPAPVPAGTPAPPGPATM
              280       290       300       310       320       330

     420       430       440       450       460       470 
pF1KB5 MPDGTLGLTPPTTERFGQAATMEGIGAIGGTPPAFNRAAPGAEFAPNKRRRY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MPDGTLGLTPPTTERFGQAATMEGIGAIGGTPPAFNRAAPGAEFAPNKRRRY
              340       350       360       370       380  

>>XP_011533439 (OMIM: 612408) PREDICTED: paraspeckle com  (469 aa)
 initn: 1679 init1: 1594 opt: 1776  Z-score: 909.3  bits: 177.6 E(85289): 6.6e-44
Smith-Waterman score: 1776; 63.8% identity (84.0% similar) in 425 aa overlap (37-460:45-463)

         10        20        30        40        50        60      
pF1KB5 FNLEKQNHTPRKHHQHHHQQQHHQQQQQQPPPPPIPANGQQASSQNEGLTIDLKNFRKPG
                                     : :: ::  ..  ... :.:::.:.: :::
XP_011 NPARLRALESAVGESEPAAAAAMALALAGEPAPPAPAPPEDHPDEEMGFTIDIKSFLKPG
           20        30        40        50        60        70    

         70        80        90       100       110       120      
pF1KB5 EKTFTQRSRLFVGNLPPDITEEEMRKLFEKYGKAGEVFIHKDKGFGFIRLETRTLAEIAK
       :::.::: :::::::: :::::....:::.::. .::::..:.::::::::.::::::::
XP_011 EKTYTQRCRLFVGNLPTDITEEDFKRLFERYGEPSEVFINRDRGFGFIRLESRTLAEIAK
           80        90       100       110       120       130    

        130       140       150       160       170       180      
pF1KB5 VELDNMPLRGKQLRVRFACHSASLTVRNLPQYVSNELLEEAFSVFGQVERAVVIVDDRGR
       .:::.  :... ::.::: :.:.:::.::   :::::::.::: :: ::.:::.::::::
XP_011 AELDGTILKSRPLRIRFATHGAALTVKNLSPVVSNELLEQAFSQFGPVEKAVVVVDDRGR
          140       150       160       170       180       190    

        190       200       210       220       230       240      
pF1KB5 PSGKGIVEFSGKPAARKALDRCSEGSFLLTTFPRPVTVEPMDQLDDEEGLPEKLVIKNQQ
        .:::.:::..:: :::::.::..:.::::: :::: ::::.:.:::.::::::. :.::
XP_011 ATGKGFVEFAAKPPARKALERCGDGAFLLTTTPRPVIVEPMEQFDDEDGLPEKLMQKTQQ
          200       210       220       230       240       250    

        250       260       270       280       290       300      
pF1KB5 FHKEREQPPRFAQPGSFEYEYAMRWKALIEMEKQQQDQVDRNIKEAREKLEMEMEAARHE
       .::::::::::::::.::.::: ::::: ::::::..::::::.::.:::: ::::::::
XP_011 YHKEREQPPRFAQPGTFEFEYASRWKALDEMEKQQREQVDRNIREAKEKLEAEMEAARHE
          260       270       280       290       300       310    

        310       320       330       340       350        360     
pF1KB5 HQVMLMRQDLMRRQEELRRMEELHNQEVQKRKQLELRQEEERRRREEEM-RRQQEEMMRR
       ::.::::::::::::::::.:::.:::.:::::..::.:::.::::::: :....: .::
XP_011 HQLMLMRQDLMRRQEELRRLEELRNQELQKRKQIQLRHEEEHRRREEEMIRHREQEELRR
          320       330       340       350       360       370    

         370       380       390       400       410       420     
pF1KB5 QQEGFKGTFPDAREQEIRMGQMAMGGAMGINNRGAMPPAPVPAGTPAPPGPATMMPDGTL
       :::::: .. . ::::.:::.:.  ::.....  :. :::  ::. .:: :   :  .. 
XP_011 QQEGFKPNYMENREQEMRMGDMGPRGAINMGD--AFSPAP--AGNQGPP-PMMGMNMNNR
          380       390       400         410          420         

         430       440       450       460       470 
pF1KB5 GLTPPTTERFGQAATMEGIGAIGGTPPAFNRAAPGAEFAPNKRRRY
       .  :      : :   :: . .: ::   . .: :           
XP_011 ATIPGPPMGPGPAMGPEGAANMG-TPMMPDNGAVGDKRKCG     
     430       440       450        460              

>>XP_006719907 (OMIM: 612408) PREDICTED: paraspeckle com  (523 aa)
 initn: 1767 init1: 1594 opt: 1773  Z-score: 907.4  bits: 177.4 E(85289): 8.4e-44
Smith-Waterman score: 1780; 60.0% identity (79.1% similar) in 468 aa overlap (37-460:45-511)

         10        20        30        40        50        60      
pF1KB5 FNLEKQNHTPRKHHQHHHQQQHHQQQQQQPPPPPIPANGQQASSQNEGLTIDLKNFRKPG
                                     : :: ::  ..  ... :.:::.:.: :::
XP_006 NPARLRALESAVGESEPAAAAAMALALAGEPAPPAPAPPEDHPDEEMGFTIDIKSFLKPG
           20        30        40        50        60        70    

         70        80        90       100       110       120      
pF1KB5 EKTFTQRSRLFVGNLPPDITEEEMRKLFEKYGKAGEVFIHKDKGFGFIRLETRTLAEIAK
       :::.::: :::::::: :::::....:::.::. .::::..:.::::::::.::::::::
XP_006 EKTYTQRCRLFVGNLPTDITEEDFKRLFERYGEPSEVFINRDRGFGFIRLESRTLAEIAK
           80        90       100       110       120       130    

        130       140       150       160       170       180      
pF1KB5 VELDNMPLRGKQLRVRFACHSASLTVRNLPQYVSNELLEEAFSVFGQVERAVVIVDDRGR
       .:::.  :... ::.::: :.:.:::.::   :::::::.::: :: ::.:::.::::::
XP_006 AELDGTILKSRPLRIRFATHGAALTVKNLSPVVSNELLEQAFSQFGPVEKAVVVVDDRGR
          140       150       160       170       180       190    

        190       200       210       220       230       240      
pF1KB5 PSGKGIVEFSGKPAARKALDRCSEGSFLLTTFPRPVTVEPMDQLDDEEGLPEKLVIKNQQ
        .:::.:::..:: :::::.::..:.::::: :::: ::::.:.:::.::::::. :.::
XP_006 ATGKGFVEFAAKPPARKALERCGDGAFLLTTTPRPVIVEPMEQFDDEDGLPEKLMQKTQQ
          200       210       220       230       240       250    

        250       260       270       280       290       300      
pF1KB5 FHKEREQPPRFAQPGSFEYEYAMRWKALIEMEKQQQDQVDRNIKEAREKLEMEMEAARHE
       .::::::::::::::.::.::: ::::: ::::::..::::::.::.:::: ::::::::
XP_006 YHKEREQPPRFAQPGTFEFEYASRWKALDEMEKQQREQVDRNIREAKEKLEAEMEAARHE
          260       270       280       290       300       310    

        310       320       330       340       350        360     
pF1KB5 HQVMLMRQDLMRRQEELRRMEELHNQEVQKRKQLELRQEEERRRREEEM-RRQQEEMMRR
       ::.::::::::::::::::.:::.:::.:::::..::.:::.::::::: :....: .::
XP_006 HQLMLMRQDLMRRQEELRRLEELRNQELQKRKQIQLRHEEEHRRREEEMIRHREQEELRR
          320       330       340       350       360       370    

         370       380             390                       400   
pF1KB5 QQEGFKGTFPDAREQEIRMGQMA------MGGA----------------MGINNRGAMPP
       :::::: .. . ::::.:::.:.      :: :                :..:::...: 
XP_006 QQEGFKPNYMENREQEMRMGDMGPRGAINMGDAFSPAPAGNQGPPPMMGMNMNNRATIPG
          380       390       400       410       420       430    

           410             420             430                440  
pF1KB5 APVPAGTPA--PPGPATM----MPDG------TLGLTPPTT------ERFGQA---ATME
        :.  : ::  : : :.:    :::.       .   ::.        : :.    : : 
XP_006 PPMGPG-PAMGPEGAANMGTPMMPDNGAVHNDRFPQGPPSQMGSPMGSRTGSETPQAPMS
          440        450       460       470       480       490   

            450       460       470  
pF1KB5 GIGAIGGTPPAFNRAAPGAEFAPNKRRRY 
       :.: ..: : .:.:.. :            
XP_006 GVGPVSGGPGGFGRGSQGGNFEGPNKRRRY
           500       510       520   

>>NP_001035879 (OMIM: 612408) paraspeckle component 1 [H  (523 aa)
 initn: 1767 init1: 1594 opt: 1773  Z-score: 907.4  bits: 177.4 E(85289): 8.4e-44
Smith-Waterman score: 1780; 60.0% identity (79.1% similar) in 468 aa overlap (37-460:45-511)

         10        20        30        40        50        60      
pF1KB5 FNLEKQNHTPRKHHQHHHQQQHHQQQQQQPPPPPIPANGQQASSQNEGLTIDLKNFRKPG
                                     : :: ::  ..  ... :.:::.:.: :::
NP_001 NPARLRALESAVGESEPAAAAAMALALAGEPAPPAPAPPEDHPDEEMGFTIDIKSFLKPG
           20        30        40        50        60        70    

         70        80        90       100       110       120      
pF1KB5 EKTFTQRSRLFVGNLPPDITEEEMRKLFEKYGKAGEVFIHKDKGFGFIRLETRTLAEIAK
       :::.::: :::::::: :::::....:::.::. .::::..:.::::::::.::::::::
NP_001 EKTYTQRCRLFVGNLPTDITEEDFKRLFERYGEPSEVFINRDRGFGFIRLESRTLAEIAK
           80        90       100       110       120       130    

        130       140       150       160       170       180      
pF1KB5 VELDNMPLRGKQLRVRFACHSASLTVRNLPQYVSNELLEEAFSVFGQVERAVVIVDDRGR
       .:::.  :... ::.::: :.:.:::.::   :::::::.::: :: ::.:::.::::::
NP_001 AELDGTILKSRPLRIRFATHGAALTVKNLSPVVSNELLEQAFSQFGPVEKAVVVVDDRGR
          140       150       160       170       180       190    

        190       200       210       220       230       240      
pF1KB5 PSGKGIVEFSGKPAARKALDRCSEGSFLLTTFPRPVTVEPMDQLDDEEGLPEKLVIKNQQ
        .:::.:::..:: :::::.::..:.::::: :::: ::::.:.:::.::::::. :.::
NP_001 ATGKGFVEFAAKPPARKALERCGDGAFLLTTTPRPVIVEPMEQFDDEDGLPEKLMQKTQQ
          200       210       220       230       240       250    

        250       260       270       280       290       300      
pF1KB5 FHKEREQPPRFAQPGSFEYEYAMRWKALIEMEKQQQDQVDRNIKEAREKLEMEMEAARHE
       .::::::::::::::.::.::: ::::: ::::::..::::::.::.:::: ::::::::
NP_001 YHKEREQPPRFAQPGTFEFEYASRWKALDEMEKQQREQVDRNIREAKEKLEAEMEAARHE
          260       270       280       290       300       310    

        310       320       330       340       350        360     
pF1KB5 HQVMLMRQDLMRRQEELRRMEELHNQEVQKRKQLELRQEEERRRREEEM-RRQQEEMMRR
       ::.::::::::::::::::.:::.:::.:::::..::.:::.::::::: :....: .::
NP_001 HQLMLMRQDLMRRQEELRRLEELRNQELQKRKQIQLRHEEEHRRREEEMIRHREQEELRR
          320       330       340       350       360       370    

         370       380             390                       400   
pF1KB5 QQEGFKGTFPDAREQEIRMGQMA------MGGA----------------MGINNRGAMPP
       :::::: .. . ::::.:::.:.      :: :                :..:::...: 
NP_001 QQEGFKPNYMENREQEMRMGDMGPRGAINMGDAFSPAPAGNQGPPPMMGMNMNNRATIPG
          380       390       400       410       420       430    

           410             420             430                440  
pF1KB5 APVPAGTPA--PPGPATM----MPDG------TLGLTPPTT------ERFGQA---ATME
        :.  : ::  : : :.:    :::.       .   ::.        : :.    : : 
NP_001 PPMGPG-PAMGPEGAANMGTPMMPDNGAVHNDRFPQGPPSQMGSPMGSRTGSETPQAPMS
          440        450       460       470       480       490   

            450       460       470  
pF1KB5 GIGAIGGTPPAFNRAAPGAEFAPNKRRRY 
       :.: ..: : .:.:.. :            
NP_001 GVGPVSGGPGGFGRGSQGGNFEGPNKRRRY
           500       510       520   

>>XP_016857543 (OMIM: 605199) PREDICTED: splicing factor  (707 aa)
 initn: 1765 init1: 1622 opt: 1716  Z-score: 877.7  bits: 172.3 E(85289): 3.8e-42
Smith-Waterman score: 1778; 60.0% identity (79.9% similar) in 473 aa overlap (16-471:241-707)

                              10        20        30        40     
pF1KB5                MQSNKTFNLEKQNHTPRKHHQHHHQQQHHQQQQQQPPPPPIPANG
                                     ::  .:::    .:::..: :::    . .
XP_016 KMPGGPKPGGGPGLSTPGGHPKPPHRGGGEPRGGRQHH--PPYHQQHHQGPPPGGPGGRS
              220       230       240         250       260        

          50        60        70        80        90       100     
pF1KB5 QQASSQNEGLTIDLKNFRKPGEKTFTQRSRLFVGNLPPDITEEEMRKLFEKYGKAGEVFI
       ..  :..::.  .:. .:.:::::.::: :::::::: ::::.:...:: :::. :::::
XP_016 EEKISDSEGFKANLSLLRRPGEKTYTQRCRLFVGNLPADITEDEFKRLFAKYGEPGEVFI
      270       280       290       300       310       320        

         110       120       130       140       150       160     
pF1KB5 HKDKGFGFIRLETRTLAEIAKVELDNMPLRGKQLRVRFACHSASLTVRNLPQYVSNELLE
       .: ::::::.::.:.::::::.:::. :.::.::::::: :.:.:.::::  ::::::::
XP_016 NKGKGFGFIKLESRALAEIAKAELDDTPMRGRQLRVRFATHAAALSVRNLSPYVSNELLE
      330       340       350       360       370       380        

         170       180       190       200       210       220     
pF1KB5 EAFSVFGQVERAVVIVDDRGRPSGKGIVEFSGKPAARKALDRCSEGSFLLTTFPRPVTVE
       :::: :: .:::::::::::: .:::::::..:::::::..::::: ::::: :::: ::
XP_016 EAFSQFGPIERAVVIVDDRGRSTGKGIVEFASKPAARKAFERCSEGVFLLTTTPRPVIVE
      390       400       410       420       430       440        

         230       240       250       260       270       280     
pF1KB5 PMDQLDDEEGLPEKLVIKNQQFHKEREQPPRFAQPGSFEYEYAMRWKALIEMEKQQQDQV
       :..:::::.::::::. :: ...:::: :::::: :.:::::..:::.: ::::::..::
XP_016 PLEQLDDEDGLPEKLAQKNPMYQKERETPPRFAQHGTFEYEYSQRWKSLDEMEKQQREQV
      450       460       470       480       490       500        

         290       300       310       320       330       340     
pF1KB5 DRNIKEAREKLEMEMEAARHEHQVMLMRQDLMRRQEELRRMEELHNQEVQKRKQLELRQE
       ..:.:.:..::: ::: : ::::. :.:::::::::::::::::::::.::::...::::
XP_016 EKNMKDAKDKLESEMEDAYHEHQANLLRQDLMRRQEELRRMEELHNQEMQKRKEMQLRQE
      510       520       530       540       550       560        

         350          360        370        380          390       
pF1KB5 EERRRREEEM---RRQQEEMMRRQ-QEGF-KGTFPDAREQEIRMG---QMAMGGAMGINN
       ::::::::::   .:..::.:::: .:.. .  . : ::...:::    : ::  .: ..
XP_016 EERRRREEEMMIRQREMEEQMRRQREESYSRMGYMDPRERDMRMGGGGAMNMGDPYGSGG
      570       580       590       600       610       620        

       400       410           420       430         440           
pF1KB5 RGAMPPAPVPAGT--PAPPG--PATMMPDGTLGLTPPTTERFGQ--AATMEGIGAIG---
       .  .::    .:    : ::  ::::  .:..  .   ::::::  :. . : :  :   
XP_016 Q-KFPPLGGGGGIGYEANPGVPPATM--SGSMMGSDMRTERFGQGGAGPVGGQGPRGMGP
       630       640       650         660       670       680     

      450       460       470 
pF1KB5 GTPPAFNRAAPGAEFAPNKRRRY
       ::: ...:.    : .:::. :.
XP_016 GTPAGYGRGREEYE-GPNKKPRF
         690        700       

>>XP_005271170 (OMIM: 605199) PREDICTED: splicing factor  (707 aa)
 initn: 1765 init1: 1622 opt: 1716  Z-score: 877.7  bits: 172.3 E(85289): 3.8e-42
Smith-Waterman score: 1778; 60.0% identity (79.9% similar) in 473 aa overlap (16-471:241-707)

                              10        20        30        40     
pF1KB5                MQSNKTFNLEKQNHTPRKHHQHHHQQQHHQQQQQQPPPPPIPANG
                                     ::  .:::    .:::..: :::    . .
XP_005 KMPGGPKPGGGPGLSTPGGHPKPPHRGGGEPRGGRQHH--PPYHQQHHQGPPPGGPGGRS
              220       230       240         250       260        

          50        60        70        80        90       100     
pF1KB5 QQASSQNEGLTIDLKNFRKPGEKTFTQRSRLFVGNLPPDITEEEMRKLFEKYGKAGEVFI
       ..  :..::.  .:. .:.:::::.::: :::::::: ::::.:...:: :::. :::::
XP_005 EEKISDSEGFKANLSLLRRPGEKTYTQRCRLFVGNLPADITEDEFKRLFAKYGEPGEVFI
      270       280       290       300       310       320        

         110       120       130       140       150       160     
pF1KB5 HKDKGFGFIRLETRTLAEIAKVELDNMPLRGKQLRVRFACHSASLTVRNLPQYVSNELLE
       .: ::::::.::.:.::::::.:::. :.::.::::::: :.:.:.::::  ::::::::
XP_005 NKGKGFGFIKLESRALAEIAKAELDDTPMRGRQLRVRFATHAAALSVRNLSPYVSNELLE
      330       340       350       360       370       380        

         170       180       190       200       210       220     
pF1KB5 EAFSVFGQVERAVVIVDDRGRPSGKGIVEFSGKPAARKALDRCSEGSFLLTTFPRPVTVE
       :::: :: .:::::::::::: .:::::::..:::::::..::::: ::::: :::: ::
XP_005 EAFSQFGPIERAVVIVDDRGRSTGKGIVEFASKPAARKAFERCSEGVFLLTTTPRPVIVE
      390       400       410       420       430       440        

         230       240       250       260       270       280     
pF1KB5 PMDQLDDEEGLPEKLVIKNQQFHKEREQPPRFAQPGSFEYEYAMRWKALIEMEKQQQDQV
       :..:::::.::::::. :: ...:::: :::::: :.:::::..:::.: ::::::..::
XP_005 PLEQLDDEDGLPEKLAQKNPMYQKERETPPRFAQHGTFEYEYSQRWKSLDEMEKQQREQV
      450       460       470       480       490       500        

         290       300       310       320       330       340     
pF1KB5 DRNIKEAREKLEMEMEAARHEHQVMLMRQDLMRRQEELRRMEELHNQEVQKRKQLELRQE
       ..:.:.:..::: ::: : ::::. :.:::::::::::::::::::::.::::...::::
XP_005 EKNMKDAKDKLESEMEDAYHEHQANLLRQDLMRRQEELRRMEELHNQEMQKRKEMQLRQE
      510       520       530       540       550       560        

         350          360        370        380          390       
pF1KB5 EERRRREEEM---RRQQEEMMRRQ-QEGF-KGTFPDAREQEIRMG---QMAMGGAMGINN
       ::::::::::   .:..::.:::: .:.. .  . : ::...:::    : ::  .: ..
XP_005 EERRRREEEMMIRQREMEEQMRRQREESYSRMGYMDPRERDMRMGGGGAMNMGDPYGSGG
      570       580       590       600       610       620        

       400       410           420       430         440           
pF1KB5 RGAMPPAPVPAGT--PAPPG--PATMMPDGTLGLTPPTTERFGQ--AATMEGIGAIG---
       .  .::    .:    : ::  ::::  .:..  .   ::::::  :. . : :  :   
XP_005 Q-KFPPLGGGGGIGYEANPGVPPATM--SGSMMGSDMRTERFGQGGAGPVGGQGPRGMGP
       630       640       650         660       670       680     

      450       460       470 
pF1KB5 GTPPAFNRAAPGAEFAPNKRRRY
       ::: ...:.    : .:::. :.
XP_005 GTPAGYGRGREEYE-GPNKKPRF
         690        700       

>>XP_005271169 (OMIM: 605199) PREDICTED: splicing factor  (707 aa)
 initn: 1765 init1: 1622 opt: 1716  Z-score: 877.7  bits: 172.3 E(85289): 3.8e-42
Smith-Waterman score: 1778; 60.0% identity (79.9% similar) in 473 aa overlap (16-471:241-707)

                              10        20        30        40     
pF1KB5                MQSNKTFNLEKQNHTPRKHHQHHHQQQHHQQQQQQPPPPPIPANG
                                     ::  .:::    .:::..: :::    . .
XP_005 KMPGGPKPGGGPGLSTPGGHPKPPHRGGGEPRGGRQHH--PPYHQQHHQGPPPGGPGGRS
              220       230       240         250       260        

          50        60        70        80        90       100     
pF1KB5 QQASSQNEGLTIDLKNFRKPGEKTFTQRSRLFVGNLPPDITEEEMRKLFEKYGKAGEVFI
       ..  :..::.  .:. .:.:::::.::: :::::::: ::::.:...:: :::. :::::
XP_005 EEKISDSEGFKANLSLLRRPGEKTYTQRCRLFVGNLPADITEDEFKRLFAKYGEPGEVFI
      270       280       290       300       310       320        

         110       120       130       140       150       160     
pF1KB5 HKDKGFGFIRLETRTLAEIAKVELDNMPLRGKQLRVRFACHSASLTVRNLPQYVSNELLE
       .: ::::::.::.:.::::::.:::. :.::.::::::: :.:.:.::::  ::::::::
XP_005 NKGKGFGFIKLESRALAEIAKAELDDTPMRGRQLRVRFATHAAALSVRNLSPYVSNELLE
      330       340       350       360       370       380        

         170       180       190       200       210       220     
pF1KB5 EAFSVFGQVERAVVIVDDRGRPSGKGIVEFSGKPAARKALDRCSEGSFLLTTFPRPVTVE
       :::: :: .:::::::::::: .:::::::..:::::::..::::: ::::: :::: ::
XP_005 EAFSQFGPIERAVVIVDDRGRSTGKGIVEFASKPAARKAFERCSEGVFLLTTTPRPVIVE
      390       400       410       420       430       440        

         230       240       250       260       270       280     
pF1KB5 PMDQLDDEEGLPEKLVIKNQQFHKEREQPPRFAQPGSFEYEYAMRWKALIEMEKQQQDQV
       :..:::::.::::::. :: ...:::: :::::: :.:::::..:::.: ::::::..::
XP_005 PLEQLDDEDGLPEKLAQKNPMYQKERETPPRFAQHGTFEYEYSQRWKSLDEMEKQQREQV
      450       460       470       480       490       500        

         290       300       310       320       330       340     
pF1KB5 DRNIKEAREKLEMEMEAARHEHQVMLMRQDLMRRQEELRRMEELHNQEVQKRKQLELRQE
       ..:.:.:..::: ::: : ::::. :.:::::::::::::::::::::.::::...::::
XP_005 EKNMKDAKDKLESEMEDAYHEHQANLLRQDLMRRQEELRRMEELHNQEMQKRKEMQLRQE
      510       520       530       540       550       560        

         350          360        370        380          390       
pF1KB5 EERRRREEEM---RRQQEEMMRRQ-QEGF-KGTFPDAREQEIRMG---QMAMGGAMGINN
       ::::::::::   .:..::.:::: .:.. .  . : ::...:::    : ::  .: ..
XP_005 EERRRREEEMMIRQREMEEQMRRQREESYSRMGYMDPRERDMRMGGGGAMNMGDPYGSGG
      570       580       590       600       610       620        

       400       410           420       430         440           
pF1KB5 RGAMPPAPVPAGT--PAPPG--PATMMPDGTLGLTPPTTERFGQ--AATMEGIGAIG---
       .  .::    .:    : ::  ::::  .:..  .   ::::::  :. . : :  :   
XP_005 Q-KFPPLGGGGGIGYEANPGVPPATM--SGSMMGSDMRTERFGQGGAGPVGGQGPRGMGP
       630       640       650         660       670       680     

      450       460       470 
pF1KB5 GTPPAFNRAAPGAEFAPNKRRRY
       ::: ...:.    : .:::. :.
XP_005 GTPAGYGRGREEYE-GPNKKPRF
         690        700       




471 residues in 1 query   sequences
60827320 residues in 85289 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Fri Nov  4 03:42:58 2016 done: Fri Nov  4 03:43:00 2016
 Total Scan time: 11.070 Total Display time:  0.070

Function used was FASTA [36.3.4 Apr, 2011]
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