Result of FASTA (omim) for pF1KB4977
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KB4977, 400 aa
  1>>>pF1KB4977 400 - 400 aa - 400 aa
Library: /omim/omim.rfq.tfa
  60827320 residues in 85289 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 6.3898+/-0.000414; mu= 11.8676+/- 0.026
 mean_var=116.4731+/-24.627, 0's: 0 Z-trim(113.9): 180  B-trim: 353 in 2/54
 Lambda= 0.118840
 statistics sampled from 23308 (23533) to 23308 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.642), E-opt: 0.2 (0.276), width:  16
 Scan time:  6.730

The best scores are:                                      opt bits E(85289)
NP_003788 (OMIM: 605984) polycomb protein EED isof ( 441) 2783 488.6 1.3e-137
XP_016874001 (OMIM: 605984) PREDICTED: polycomb pr ( 403) 2777 487.5 2.4e-137
XP_011543633 (OMIM: 605984) PREDICTED: polycomb pr ( 415) 2224 392.7 8.7e-109
XP_011543632 (OMIM: 605984) PREDICTED: polycomb pr ( 428) 2224 392.7 8.9e-109
NP_001294936 (OMIM: 605984) polycomb protein EED i ( 466) 2224 392.7 9.5e-109
XP_016874002 (OMIM: 605984) PREDICTED: polycomb pr ( 323) 1655 295.1 1.7e-79
NP_001317263 (OMIM: 605984) polycomb protein EED i ( 361) 1655 295.1 1.8e-79
NP_004362 (OMIM: 601924,616414) coatomer subunit a (1224)  188 44.0  0.0024
NP_001091868 (OMIM: 601924,616414) coatomer subuni (1233)  188 44.0  0.0024
NP_001186706 (OMIM: 614784,615973) POC1 centriolar ( 436)  181 42.4  0.0025
NP_758440 (OMIM: 614784,615973) POC1 centriolar pr ( 478)  181 42.5  0.0027
XP_016861593 (OMIM: 614783,614813) PREDICTED: POC1 ( 321)  172 40.8  0.0058
NP_942593 (OMIM: 610767,611081) autophagy-related  ( 444)  174 41.2  0.0058
XP_005246143 (OMIM: 610767,611081) PREDICTED: auto ( 463)  174 41.3   0.006
XP_005246141 (OMIM: 610767,611081) PREDICTED: auto ( 480)  174 41.3  0.0062
NP_001155052 (OMIM: 614783,614813) POC1 centriolar ( 359)  172 40.8  0.0063
NP_001177196 (OMIM: 610767,611081) autophagy-relat ( 491)  174 41.3  0.0063
NP_001155053 (OMIM: 614783,614813) POC1 centriolar ( 369)  172 40.8  0.0064
NP_001177195 (OMIM: 610767,611081) autophagy-relat ( 523)  174 41.3  0.0066
XP_006712671 (OMIM: 610767,611081) PREDICTED: auto ( 540)  174 41.3  0.0067
NP_056241 (OMIM: 614783,614813) POC1 centriolar pr ( 407)  172 40.9  0.0069
NP_060444 (OMIM: 610767,611081) autophagy-related  ( 588)  174 41.3  0.0072
NP_110430 (OMIM: 610767,611081) autophagy-related  ( 607)  174 41.4  0.0074
XP_005246139 (OMIM: 610767,611081) PREDICTED: auto ( 624)  174 41.4  0.0075
NP_001269469 (OMIM: 604596) CMT1A duplicated regio ( 714)  174 41.4  0.0083
XP_016879510 (OMIM: 611679) PREDICTED: F-box/WD re ( 724)  174 41.4  0.0084
XP_011521928 (OMIM: 611679) PREDICTED: F-box/WD re ( 745)  174 41.4  0.0086
NP_006373 (OMIM: 604596) CMT1A duplicated region t ( 752)  174 41.4  0.0087
XP_011521927 (OMIM: 611679) PREDICTED: F-box/WD re ( 856)  174 41.5  0.0095
XP_016879509 (OMIM: 611679) PREDICTED: F-box/WD re ( 856)  174 41.5  0.0095


>>NP_003788 (OMIM: 605984) polycomb protein EED isoform   (441 aa)
 initn: 2783 init1: 2783 opt: 2783  Z-score: 2591.7  bits: 488.6 E(85289): 1.3e-137
Smith-Waterman score: 2783; 100.0% identity (100.0% similar) in 400 aa overlap (1-400:1-400)

               10        20        30        40        50        60
pF1KB4 MSEREVSTAPAGTDMPAAKKQKLSSDENSNPDLSGDENDDAVSIESGTNTERPDTPTNTP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 MSEREVSTAPAGTDMPAAKKQKLSSDENSNPDLSGDENDDAVSIESGTNTERPDTPTNTP
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB4 NAPGRKSWGKGKWKSKKCKYSFKCVNSLKEDHNQPLFGVQFNWHSKEGDPLVFATVGSNR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 NAPGRKSWGKGKWKSKKCKYSFKCVNSLKEDHNQPLFGVQFNWHSKEGDPLVFATVGSNR
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB4 VTLYECHSQGEIRLLQSYVDADADENFYTCAWTYDSNTSHPLLAVAGSRGIIRIINPITM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 VTLYECHSQGEIRLLQSYVDADADENFYTCAWTYDSNTSHPLLAVAGSRGIIRIINPITM
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB4 QCIKHYVGHGNAINELKFHPRDPNLLLSVSKDHALRLWNIQTDTLVAIFGGVEGHRDEVL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 QCIKHYVGHGNAINELKFHPRDPNLLLSVSKDHALRLWNIQTDTLVAIFGGVEGHRDEVL
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB4 SADYDLLGEKIMSCGMDHSLKLWRINSKRMMNAIKESYDYNPNKTNRPFISQKIHFPDFS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 SADYDLLGEKIMSCGMDHSLKLWRINSKRMMNAIKESYDYNPNKTNRPFISQKIHFPDFS
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KB4 TRDIHRNYVDCVRWLGDLILSKSCENAIVCWKPGKMEDDIDKIKPSESNVTILGRFDYSQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 TRDIHRNYVDCVRWLGDLILSKSCENAIVCWKPGKMEDDIDKIKPSESNVTILGRFDYSQ
              310       320       330       340       350       360

              370       380       390       400                    
pF1KB4 CDIWYMRFSMDFWQKMLALGNQVGKLYVWDLEVEDPHKAK                    
       ::::::::::::::::::::::::::::::::::::::::                    
NP_003 CDIWYMRFSMDFWQKMLALGNQVGKLYVWDLEVEDPHKAKCTTLTHHKCGAAIRQTSFSR
              370       380       390       400       410       420

NP_003 DSSILIAVCDDASIWRWDRLR
              430       440 

>>XP_016874001 (OMIM: 605984) PREDICTED: polycomb protei  (403 aa)
 initn: 2777 init1: 2777 opt: 2777  Z-score: 2586.7  bits: 487.5 E(85289): 2.4e-137
Smith-Waterman score: 2777; 100.0% identity (100.0% similar) in 399 aa overlap (1-399:1-399)

               10        20        30        40        50        60
pF1KB4 MSEREVSTAPAGTDMPAAKKQKLSSDENSNPDLSGDENDDAVSIESGTNTERPDTPTNTP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MSEREVSTAPAGTDMPAAKKQKLSSDENSNPDLSGDENDDAVSIESGTNTERPDTPTNTP
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB4 NAPGRKSWGKGKWKSKKCKYSFKCVNSLKEDHNQPLFGVQFNWHSKEGDPLVFATVGSNR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NAPGRKSWGKGKWKSKKCKYSFKCVNSLKEDHNQPLFGVQFNWHSKEGDPLVFATVGSNR
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB4 VTLYECHSQGEIRLLQSYVDADADENFYTCAWTYDSNTSHPLLAVAGSRGIIRIINPITM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VTLYECHSQGEIRLLQSYVDADADENFYTCAWTYDSNTSHPLLAVAGSRGIIRIINPITM
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB4 QCIKHYVGHGNAINELKFHPRDPNLLLSVSKDHALRLWNIQTDTLVAIFGGVEGHRDEVL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QCIKHYVGHGNAINELKFHPRDPNLLLSVSKDHALRLWNIQTDTLVAIFGGVEGHRDEVL
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB4 SADYDLLGEKIMSCGMDHSLKLWRINSKRMMNAIKESYDYNPNKTNRPFISQKIHFPDFS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SADYDLLGEKIMSCGMDHSLKLWRINSKRMMNAIKESYDYNPNKTNRPFISQKIHFPDFS
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KB4 TRDIHRNYVDCVRWLGDLILSKSCENAIVCWKPGKMEDDIDKIKPSESNVTILGRFDYSQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TRDIHRNYVDCVRWLGDLILSKSCENAIVCWKPGKMEDDIDKIKPSESNVTILGRFDYSQ
              310       320       330       340       350       360

              370       380       390       400   
pF1KB4 CDIWYMRFSMDFWQKMLALGNQVGKLYVWDLEVEDPHKAK   
       :::::::::::::::::::::::::::::::::::::::    
XP_016 CDIWYMRFSMDFWQKMLALGNQVGKLYVWDLEVEDPHKANRDH
              370       380       390       400   

>>XP_011543633 (OMIM: 605984) PREDICTED: polycomb protei  (415 aa)
 initn: 2223 init1: 2223 opt: 2224  Z-score: 2074.1  bits: 392.7 E(85289): 8.7e-109
Smith-Waterman score: 2552; 93.8% identity (93.8% similar) in 400 aa overlap (1-375:1-400)

               10        20        30        40        50        60
pF1KB4 MSEREVSTAPAGTDMPAAKKQKLSSDENSNPDLSGDENDDAVSIESGTNTERPDTPTNTP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MSEREVSTAPAGTDMPAAKKQKLSSDENSNPDLSGDENDDAVSIESGTNTERPDTPTNTP
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB4 NAPGRKSWGKGKWKSKKCKYSFKCVNSLKEDHNQPLFGVQFNWHSKEGDPLVFATVGSNR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NAPGRKSWGKGKWKSKKCKYSFKCVNSLKEDHNQPLFGVQFNWHSKEGDPLVFATVGSNR
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB4 VTLYECHSQGEIRLLQSYVDADADENFYTCAWTYDSNTSHPLLAVAGSRGIIRIINPITM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VTLYECHSQGEIRLLQSYVDADADENFYTCAWTYDSNTSHPLLAVAGSRGIIRIINPITM
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB4 QCIKHYVGHGNAINELKFHPRDPNLLLSVSKDHALRLWNIQTDTLVAIFGGVEGHRDEVL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QCIKHYVGHGNAINELKFHPRDPNLLLSVSKDHALRLWNIQTDTLVAIFGGVEGHRDEVL
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB4 SADYDLLGEKIMSCGMDHSLKLWRINSKRMMNAIKESYDYNPNKTNRPFISQKIHFPDFS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SADYDLLGEKIMSCGMDHSLKLWRINSKRMMNAIKESYDYNPNKTNRPFISQKIHFPDFS
              250       260       270       280       290       300

              310       320                                330     
pF1KB4 TRDIHRNYVDCVRWLGDLILSKS-------------------------CENAIVCWKPGK
       :::::::::::::::::::::::                         ::::::::::::
XP_011 TRDIHRNYVDCVRWLGDLILSKSGRAILHSHQQCMRDPVSPNLRQHLSCENAIVCWKPGK
              310       320       330       340       350       360

         340       350       360       370       380       390     
pF1KB4 MEDDIDKIKPSESNVTILGRFDYSQCDIWYMRFSMDFWQKMLALGNQVGKLYVWDLEVED
       ::::::::::::::::::::::::::::::::::::::::                    
XP_011 MEDDIDKIKPSESNVTILGRFDYSQCDIWYMRFSMDFWQKEYKTQRNSQEHRGWN     
              370       380       390       400       410          

         400
pF1KB4 PHKAK

>>XP_011543632 (OMIM: 605984) PREDICTED: polycomb protei  (428 aa)
 initn: 2223 init1: 2223 opt: 2224  Z-score: 2073.9  bits: 392.7 E(85289): 8.9e-109
Smith-Waterman score: 2717; 94.1% identity (94.1% similar) in 424 aa overlap (1-399:1-424)

               10        20        30        40        50        60
pF1KB4 MSEREVSTAPAGTDMPAAKKQKLSSDENSNPDLSGDENDDAVSIESGTNTERPDTPTNTP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MSEREVSTAPAGTDMPAAKKQKLSSDENSNPDLSGDENDDAVSIESGTNTERPDTPTNTP
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB4 NAPGRKSWGKGKWKSKKCKYSFKCVNSLKEDHNQPLFGVQFNWHSKEGDPLVFATVGSNR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NAPGRKSWGKGKWKSKKCKYSFKCVNSLKEDHNQPLFGVQFNWHSKEGDPLVFATVGSNR
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB4 VTLYECHSQGEIRLLQSYVDADADENFYTCAWTYDSNTSHPLLAVAGSRGIIRIINPITM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VTLYECHSQGEIRLLQSYVDADADENFYTCAWTYDSNTSHPLLAVAGSRGIIRIINPITM
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB4 QCIKHYVGHGNAINELKFHPRDPNLLLSVSKDHALRLWNIQTDTLVAIFGGVEGHRDEVL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QCIKHYVGHGNAINELKFHPRDPNLLLSVSKDHALRLWNIQTDTLVAIFGGVEGHRDEVL
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB4 SADYDLLGEKIMSCGMDHSLKLWRINSKRMMNAIKESYDYNPNKTNRPFISQKIHFPDFS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SADYDLLGEKIMSCGMDHSLKLWRINSKRMMNAIKESYDYNPNKTNRPFISQKIHFPDFS
              250       260       270       280       290       300

              310       320                                330     
pF1KB4 TRDIHRNYVDCVRWLGDLILSKS-------------------------CENAIVCWKPGK
       :::::::::::::::::::::::                         ::::::::::::
XP_011 TRDIHRNYVDCVRWLGDLILSKSGRAILHSHQQCMRDPVSPNLRQHLSCENAIVCWKPGK
              310       320       330       340       350       360

         340       350       360       370       380       390     
pF1KB4 MEDDIDKIKPSESNVTILGRFDYSQCDIWYMRFSMDFWQKMLALGNQVGKLYVWDLEVED
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MEDDIDKIKPSESNVTILGRFDYSQCDIWYMRFSMDFWQKMLALGNQVGKLYVWDLEVED
              370       380       390       400       410       420

         400   
pF1KB4 PHKAK   
       ::::    
XP_011 PHKANRDH
               

>>NP_001294936 (OMIM: 605984) polycomb protein EED isofo  (466 aa)
 initn: 2223 init1: 2223 opt: 2224  Z-score: 2073.4  bits: 392.7 E(85289): 9.5e-109
Smith-Waterman score: 2723; 94.1% identity (94.1% similar) in 425 aa overlap (1-400:1-425)

               10        20        30        40        50        60
pF1KB4 MSEREVSTAPAGTDMPAAKKQKLSSDENSNPDLSGDENDDAVSIESGTNTERPDTPTNTP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MSEREVSTAPAGTDMPAAKKQKLSSDENSNPDLSGDENDDAVSIESGTNTERPDTPTNTP
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB4 NAPGRKSWGKGKWKSKKCKYSFKCVNSLKEDHNQPLFGVQFNWHSKEGDPLVFATVGSNR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NAPGRKSWGKGKWKSKKCKYSFKCVNSLKEDHNQPLFGVQFNWHSKEGDPLVFATVGSNR
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB4 VTLYECHSQGEIRLLQSYVDADADENFYTCAWTYDSNTSHPLLAVAGSRGIIRIINPITM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VTLYECHSQGEIRLLQSYVDADADENFYTCAWTYDSNTSHPLLAVAGSRGIIRIINPITM
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB4 QCIKHYVGHGNAINELKFHPRDPNLLLSVSKDHALRLWNIQTDTLVAIFGGVEGHRDEVL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QCIKHYVGHGNAINELKFHPRDPNLLLSVSKDHALRLWNIQTDTLVAIFGGVEGHRDEVL
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB4 SADYDLLGEKIMSCGMDHSLKLWRINSKRMMNAIKESYDYNPNKTNRPFISQKIHFPDFS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SADYDLLGEKIMSCGMDHSLKLWRINSKRMMNAIKESYDYNPNKTNRPFISQKIHFPDFS
              250       260       270       280       290       300

              310       320                                330     
pF1KB4 TRDIHRNYVDCVRWLGDLILSKS-------------------------CENAIVCWKPGK
       :::::::::::::::::::::::                         ::::::::::::
NP_001 TRDIHRNYVDCVRWLGDLILSKSGRAILHSHQQCMRDPVSPNLRQHLSCENAIVCWKPGK
              310       320       330       340       350       360

         340       350       360       370       380       390     
pF1KB4 MEDDIDKIKPSESNVTILGRFDYSQCDIWYMRFSMDFWQKMLALGNQVGKLYVWDLEVED
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MEDDIDKIKPSESNVTILGRFDYSQCDIWYMRFSMDFWQKMLALGNQVGKLYVWDLEVED
              370       380       390       400       410       420

         400                                         
pF1KB4 PHKAK                                         
       :::::                                         
NP_001 PHKAKCTTLTHHKCGAAIRQTSFSRDSSILIAVCDDASIWRWDRLR
              430       440       450       460      

>>XP_016874002 (OMIM: 605984) PREDICTED: polycomb protei  (323 aa)
 initn: 1677 init1: 1655 opt: 1655  Z-score: 1548.3  bits: 295.1 E(85289): 1.7e-79
Smith-Waterman score: 2044; 79.9% identity (79.9% similar) in 399 aa overlap (1-399:1-319)

               10        20        30        40        50        60
pF1KB4 MSEREVSTAPAGTDMPAAKKQKLSSDENSNPDLSGDENDDAVSIESGTNTERPDTPTNTP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MSEREVSTAPAGTDMPAAKKQKLSSDENSNPDLSGDENDDAVSIESGTNTERPDTPTNTP
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB4 NAPGRKSWGKGKWKSKKCKYSFKCVNSLKEDHNQPLFGVQFNWHSKEGDPLVFATVGSNR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NAPGRKSWGKGKWKSKKCKYSFKCVNSLKEDHNQPLFGVQFNWHSKEGDPLVFATVGSNR
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB4 VTLYECHSQGEIRLLQSYVDADADENFYTCAWTYDSNTSHPLLAVAGSRGIIRIINPITM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VTLYECHSQGEIRLLQSYVDADADENFYTCAWTYDSNTSHPLLAVAGSRGIIRIINPITM
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB4 QCIKHYVGHGNAINELKFHPRDPNLLLSVSKDHALRLWNIQTDTLVAIFGGVEGHRDEVL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QCIKHYVGHGNAINELKFHPRDPNLLLSVSKDHALRLWNIQTDTLVAIFGGVEGHRDEVL
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB4 SADYDLLGEKIMSCGMDHSLKLWRINSKRMMNAIKESYDYNPNKTNRPFISQKIHFPDFS
       ::                                                          
XP_016 SA----------------------------------------------------------
                                                                   

              310       320       330       340       350       360
pF1KB4 TRDIHRNYVDCVRWLGDLILSKSCENAIVCWKPGKMEDDIDKIKPSESNVTILGRFDYSQ
                             ::::::::::::::::::::::::::::::::::::::
XP_016 ----------------------SCENAIVCWKPGKMEDDIDKIKPSESNVTILGRFDYSQ
                                  250       260       270       280

              370       380       390       400   
pF1KB4 CDIWYMRFSMDFWQKMLALGNQVGKLYVWDLEVEDPHKAK   
       :::::::::::::::::::::::::::::::::::::::    
XP_016 CDIWYMRFSMDFWQKMLALGNQVGKLYVWDLEVEDPHKANRDH
              290       300       310       320   

>>NP_001317263 (OMIM: 605984) polycomb protein EED isofo  (361 aa)
 initn: 1655 init1: 1655 opt: 1655  Z-score: 1547.7  bits: 295.1 E(85289): 1.8e-79
Smith-Waterman score: 2050; 80.0% identity (80.0% similar) in 400 aa overlap (1-400:1-320)

               10        20        30        40        50        60
pF1KB4 MSEREVSTAPAGTDMPAAKKQKLSSDENSNPDLSGDENDDAVSIESGTNTERPDTPTNTP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MSEREVSTAPAGTDMPAAKKQKLSSDENSNPDLSGDENDDAVSIESGTNTERPDTPTNTP
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB4 NAPGRKSWGKGKWKSKKCKYSFKCVNSLKEDHNQPLFGVQFNWHSKEGDPLVFATVGSNR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NAPGRKSWGKGKWKSKKCKYSFKCVNSLKEDHNQPLFGVQFNWHSKEGDPLVFATVGSNR
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB4 VTLYECHSQGEIRLLQSYVDADADENFYTCAWTYDSNTSHPLLAVAGSRGIIRIINPITM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VTLYECHSQGEIRLLQSYVDADADENFYTCAWTYDSNTSHPLLAVAGSRGIIRIINPITM
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB4 QCIKHYVGHGNAINELKFHPRDPNLLLSVSKDHALRLWNIQTDTLVAIFGGVEGHRDEVL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QCIKHYVGHGNAINELKFHPRDPNLLLSVSKDHALRLWNIQTDTLVAIFGGVEGHRDEVL
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB4 SADYDLLGEKIMSCGMDHSLKLWRINSKRMMNAIKESYDYNPNKTNRPFISQKIHFPDFS
       ::                                                          
NP_001 SA----------------------------------------------------------
                                                                   

              310       320       330       340       350       360
pF1KB4 TRDIHRNYVDCVRWLGDLILSKSCENAIVCWKPGKMEDDIDKIKPSESNVTILGRFDYSQ
                             ::::::::::::::::::::::::::::::::::::::
NP_001 ----------------------SCENAIVCWKPGKMEDDIDKIKPSESNVTILGRFDYSQ
                                  250       260       270       280

              370       380       390       400                    
pF1KB4 CDIWYMRFSMDFWQKMLALGNQVGKLYVWDLEVEDPHKAK                    
       ::::::::::::::::::::::::::::::::::::::::                    
NP_001 CDIWYMRFSMDFWQKMLALGNQVGKLYVWDLEVEDPHKAKCTTLTHHKCGAAIRQTSFSR
              290       300       310       320       330       340

NP_001 DSSILIAVCDDASIWRWDRLR
              350       360 

>>NP_004362 (OMIM: 601924,616414) coatomer subunit alpha  (1224 aa)
 initn: 116 init1:  67 opt: 188  Z-score: 181.1  bits: 44.0 E(85289): 0.0024
Smith-Waterman score: 191; 21.3% identity (53.3% similar) in 244 aa overlap (155-391:58-278)

          130       140       150       160       170       180    
pF1KB4 ECHSQGEIRLLQSYVDADADENFYTCAWTYDSNTSHPLLAVAGSRGIIRIINPITMQCIK
                                     : . ..::.. .:.   :.. :    .:. 
NP_004 LHNGVIQLWDYRMCTLIDKFDEHDGPVRGIDFHKQQPLFVSGGDDYKIKVWNYKLRRCLF
        30        40        50        60        70        80       

          190       200       210       220       230       240    
pF1KB4 HYVGHGNAINELKFHPRDPNLLLSVSKDHALRLWNIQTDTLVAIFGGVEGHRDEVLSADY
         .:: . :    :: . :  .::.: :...:.:: :. : : ..    ::   :. :..
NP_004 TLLGHLDYIRTTFFHHEYP-WILSASDDQTIRVWNWQSRTCVCVL---TGHNHYVMCAQF
        90       100        110       120       130          140   

          250       260       270       280       290         300  
pF1KB4 DLLGEKIMSCGMDHSLKLWRINSKRMMNAIKESYDYNPNKTNRPFISQKIHF--PDFSTR
           . ..: ..:.....: :.. :     :.. . .  ...   :.    :   :  ..
NP_004 HPTEDLVVSASLDQTVRVWDISGLR-----KKNLSPGAVESDVRGITGVDLFGTTDAVVK
           150       160            170       180       190        

            310            320       330       340       350       
pF1KB4 DIHRNYVDCVRWLG-----DLILSKSCENAIVCWKPGKMEDDIDKIKPSESNVTILGRFD
        . ...   : : .      ::.: . .  .  :.       ... :  : . :  :...
NP_004 HVLEGHDRGVNWAAFHPTMPLIVSGADDRQVKIWR-------MNESKAWEVD-TCRGHYN
      200       210       220       230              240        250

       360       370       380       390       400                 
pF1KB4 YSQCDIWYMRFSMDFWQKMLALGNQVGKLYVWDLEVEDPHKAK                 
         .: ... :      :...  ...  .. :::.                          
NP_004 NVSCAVFHPR------QELILSNSEDKSIRVWDMSKRTGVQTFRRDHDRFWVLAAHPNLN
              260             270       280       290       300    

NP_004 LFAAGHDGGMIVFKLERERPAYAVHGNMLHYVKDRFLRQLDFNSSKDVAVMQLRSGSKFP
          310       320       330       340       350       360    

>>NP_001091868 (OMIM: 601924,616414) coatomer subunit al  (1233 aa)
 initn: 116 init1:  67 opt: 188  Z-score: 181.1  bits: 44.0 E(85289): 0.0024
Smith-Waterman score: 191; 21.3% identity (53.3% similar) in 244 aa overlap (155-391:58-278)

          130       140       150       160       170       180    
pF1KB4 ECHSQGEIRLLQSYVDADADENFYTCAWTYDSNTSHPLLAVAGSRGIIRIINPITMQCIK
                                     : . ..::.. .:.   :.. :    .:. 
NP_001 LHNGVIQLWDYRMCTLIDKFDEHDGPVRGIDFHKQQPLFVSGGDDYKIKVWNYKLRRCLF
        30        40        50        60        70        80       

          190       200       210       220       230       240    
pF1KB4 HYVGHGNAINELKFHPRDPNLLLSVSKDHALRLWNIQTDTLVAIFGGVEGHRDEVLSADY
         .:: . :    :: . :  .::.: :...:.:: :. : : ..    ::   :. :..
NP_001 TLLGHLDYIRTTFFHHEYP-WILSASDDQTIRVWNWQSRTCVCVL---TGHNHYVMCAQF
        90       100        110       120       130          140   

          250       260       270       280       290         300  
pF1KB4 DLLGEKIMSCGMDHSLKLWRINSKRMMNAIKESYDYNPNKTNRPFISQKIHF--PDFSTR
           . ..: ..:.....: :.. :     :.. . .  ...   :.    :   :  ..
NP_001 HPTEDLVVSASLDQTVRVWDISGLR-----KKNLSPGAVESDVRGITGVDLFGTTDAVVK
           150       160            170       180       190        

            310            320       330       340       350       
pF1KB4 DIHRNYVDCVRWLG-----DLILSKSCENAIVCWKPGKMEDDIDKIKPSESNVTILGRFD
        . ...   : : .      ::.: . .  .  :.       ... :  : . :  :...
NP_001 HVLEGHDRGVNWAAFHPTMPLIVSGADDRQVKIWR-------MNESKAWEVD-TCRGHYN
      200       210       220       230              240        250

       360       370       380       390       400                 
pF1KB4 YSQCDIWYMRFSMDFWQKMLALGNQVGKLYVWDLEVEDPHKAK                 
         .: ... :      :...  ...  .. :::.                          
NP_001 NVSCAVFHPR------QELILSNSEDKSIRVWDMSKRTGVQTFRRDHDRFWVLAAHPNLN
              260             270       280       290       300    

NP_001 LFAAGHDGGMIVFKLERERPAYAVHGNMLHYVKDRFLRQLDFNSSKDVAVMQLRSGSKFP
          310       320       330       340       350       360    

>>NP_001186706 (OMIM: 614784,615973) POC1 centriolar pro  (436 aa)
 initn: 166 init1:  82 opt: 181  Z-score: 180.8  bits: 42.4 E(85289): 0.0025
Smith-Waterman score: 181; 28.6% identity (61.6% similar) in 112 aa overlap (155-266:151-258)

          130       140       150       160       170       180    
pF1KB4 ECHSQGEIRLLQSYVDADADENFYTCAWTYDSNTSHPLLAVAGSRGIIRIINPITMQCIK
                                     : : :   .: :::   ... .  . . ..
NP_001 SEDKTIKIWDTTNKQCVNNFSDSVGFANFVDFNPSGTCIASAGSDQTVKVWDVRVNKLLQ
              130       140       150       160       170       180

          190       200       210       220       230       240    
pF1KB4 HYVGHGNAINELKFHPRDPNLLLSVSKDHALRLWNIQTDTLVAIFGGVEGHRDEVLSADY
       ::  :....: ..::: . : :...:.: .:.. ..    :.     ..::   :.....
NP_001 HYQVHSGGVNCISFHP-SGNYLITASSDGTLKILDLLEGRLIYT---LQGHTGPVFTVSF
              190        200       210       220          230      

          250       260       270       280       290       300    
pF1KB4 DLLGEKIMSCGMDHSLKLWRINSKRMMNAIKESYDYNPNKTNRPFISQKIHFPDFSTRDI
       .  :: . : : : .. ::: :                                      
NP_001 SKGGELFASGGADTQVLLWRTNFDELHCKGLTKRNLKRLHFDSPPHLLDIYPRTPHPHEE
        240       250       260       270       280       290      




400 residues in 1 query   sequences
60827320 residues in 85289 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Fri Nov  4 03:19:58 2016 done: Fri Nov  4 03:19:59 2016
 Total Scan time:  6.730 Total Display time:  0.040

Function used was FASTA [36.3.4 Apr, 2011]
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