Result of FASTA (omim) for pF1KB3881
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KB3881, 369 aa
  1>>>pF1KB3881 369 - 369 aa - 369 aa
Library: /omim/omim.rfq.tfa
  60827320 residues in 85289 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 5.6606+/-0.000355; mu= 16.0190+/- 0.022
 mean_var=85.6965+/-16.484, 0's: 0 Z-trim(114.8): 168  B-trim: 73 in 1/54
 Lambda= 0.138546
 statistics sampled from 24715 (24885) to 24715 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.661), E-opt: 0.2 (0.292), width:  16
 Scan time:  8.330

The best scores are:                                      opt bits E(85289)
NP_002679 (OMIM: 602724) septin-5 isoform 1 [Homo  ( 369) 2482 505.9  6e-143
XP_006722014 (OMIM: 603696) PREDICTED: septin-4 is ( 379) 1869 383.4 4.7e-106
NP_536341 (OMIM: 603696) septin-4 isoform 3 [Homo  ( 459) 1869 383.4 5.5e-106
NP_001185642 (OMIM: 603696) septin-4 isoform 4 [Ho ( 470) 1869 383.4 5.6e-106
NP_004565 (OMIM: 603696) septin-4 isoform 1 [Homo  ( 478) 1869 383.4 5.7e-106
XP_006722012 (OMIM: 603696) PREDICTED: septin-4 is ( 483) 1869 383.4 5.7e-106
NP_001243711 (OMIM: 603696) septin-4 isoform 5 [Ho ( 493) 1869 383.4 5.8e-106
XP_006722013 (OMIM: 603696) PREDICTED: septin-4 is ( 384) 1858 381.2 2.2e-105
XP_006722015 (OMIM: 603696) PREDICTED: septin-4 is ( 360) 1855 380.5 3.2e-105
NP_001009939 (OMIM: 602724) septin-5 isoform 2 [Ho ( 346) 1699 349.3 7.5e-96
XP_006722018 (OMIM: 603696) PREDICTED: septin-4 is ( 331) 1679 345.3 1.1e-94
XP_011523213 (OMIM: 603696) PREDICTED: septin-4 is ( 331) 1679 345.3 1.1e-94
XP_006722017 (OMIM: 603696) PREDICTED: septin-4 is ( 331) 1679 345.3 1.1e-94
XP_011523214 (OMIM: 603696) PREDICTED: septin-4 is ( 331) 1679 345.3 1.1e-94
NP_001243751 (OMIM: 603696) septin-4 isoform 6 [Ho ( 331) 1679 345.3 1.1e-94
NP_443070 (OMIM: 612897) septin-1 [Homo sapiens]   ( 414) 1569 323.4 5.7e-88
XP_016878480 (OMIM: 612897) PREDICTED: septin-1 is ( 494) 1485 306.7 7.4e-83
NP_001307958 (OMIM: 601506) septin-2 isoform d [Ho ( 391) 1361 281.8 1.8e-75
NP_001269901 (OMIM: 601506) septin-2 isoform b [Ho ( 396) 1361 281.8 1.8e-75
XP_016859680 (OMIM: 601506) PREDICTED: septin-2 is ( 428) 1361 281.9 1.9e-75
XP_016859681 (OMIM: 601506) PREDICTED: septin-2 is ( 428) 1361 281.9 1.9e-75
NP_001307960 (OMIM: 601506) septin-2 isoform a [Ho ( 361) 1359 281.4 2.2e-75
NP_001008491 (OMIM: 601506) septin-2 isoform a [Ho ( 361) 1359 281.4 2.2e-75
XP_016859694 (OMIM: 601506) PREDICTED: septin-2 is ( 361) 1359 281.4 2.2e-75
NP_001307959 (OMIM: 601506) septin-2 isoform a [Ho ( 361) 1359 281.4 2.2e-75
NP_001307962 (OMIM: 601506) septin-2 isoform a [Ho ( 361) 1359 281.4 2.2e-75
XP_016859695 (OMIM: 601506) PREDICTED: septin-2 is ( 361) 1359 281.4 2.2e-75
NP_001307963 (OMIM: 601506) septin-2 isoform a [Ho ( 361) 1359 281.4 2.2e-75
NP_001008492 (OMIM: 601506) septin-2 isoform a [Ho ( 361) 1359 281.4 2.2e-75
NP_006146 (OMIM: 601506) septin-2 isoform a [Homo  ( 361) 1359 281.4 2.2e-75
NP_004395 (OMIM: 601506) septin-2 isoform a [Homo  ( 361) 1359 281.4 2.2e-75
NP_001307964 (OMIM: 601506) septin-2 isoform a [Ho ( 361) 1359 281.4 2.2e-75
NP_001307961 (OMIM: 601506) septin-2 isoform a [Ho ( 361) 1359 281.4 2.2e-75
XP_016859679 (OMIM: 601506) PREDICTED: septin-2 is ( 436) 1346 278.9 1.6e-74
XP_016859678 (OMIM: 601506) PREDICTED: septin-2 is ( 441) 1346 278.9 1.6e-74
XP_016859683 (OMIM: 601506) PREDICTED: septin-2 is ( 374) 1344 278.4 1.8e-74
XP_016859692 (OMIM: 601506) PREDICTED: septin-2 is ( 374) 1344 278.4 1.8e-74
XP_016859686 (OMIM: 601506) PREDICTED: septin-2 is ( 374) 1344 278.4 1.8e-74
XP_016859691 (OMIM: 601506) PREDICTED: septin-2 is ( 374) 1344 278.4 1.8e-74
XP_016859689 (OMIM: 601506) PREDICTED: septin-2 is ( 374) 1344 278.4 1.8e-74
XP_016859682 (OMIM: 601506) PREDICTED: septin-2 is ( 374) 1344 278.4 1.8e-74
XP_016859690 (OMIM: 601506) PREDICTED: septin-2 is ( 374) 1344 278.4 1.8e-74
XP_016859685 (OMIM: 601506) PREDICTED: septin-2 is ( 374) 1344 278.4 1.8e-74
XP_016859688 (OMIM: 601506) PREDICTED: septin-2 is ( 374) 1344 278.4 1.8e-74
XP_016859693 (OMIM: 601506) PREDICTED: septin-2 is ( 374) 1344 278.4 1.8e-74
XP_016859687 (OMIM: 601506) PREDICTED: septin-2 is ( 374) 1344 278.4 1.8e-74
XP_016859684 (OMIM: 601506) PREDICTED: septin-2 is ( 374) 1344 278.4 1.8e-74
XP_016868346 (OMIM: 603151) PREDICTED: septin-7 is ( 434) 1277 265.1 2.2e-70
XP_016868345 (OMIM: 603151) PREDICTED: septin-7 is ( 435) 1277 265.1 2.2e-70
NP_001011553 (OMIM: 603151) septin-7 isoform 2 [Ho ( 436) 1277 265.1 2.2e-70


>>NP_002679 (OMIM: 602724) septin-5 isoform 1 [Homo sapi  (369 aa)
 initn: 2482 init1: 2482 opt: 2482  Z-score: 2687.3  bits: 505.9 E(85289): 6e-143
Smith-Waterman score: 2482; 100.0% identity (100.0% similar) in 369 aa overlap (1-369:1-369)

               10        20        30        40        50        60
pF1KB3 MSTGLRYKSKLATPEDKQDIDKQYVGFATLPNQVHRKSVKKGFDFTLMVAGESGLGKSTL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 MSTGLRYKSKLATPEDKQDIDKQYVGFATLPNQVHRKSVKKGFDFTLMVAGESGLGKSTL
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB3 VHSLFLTDLYKDRKLLSAEERISQTVEILKHTVDIEEKGVKLKLTIVDTPGFGDAVNNTE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 VHSLFLTDLYKDRKLLSAEERISQTVEILKHTVDIEEKGVKLKLTIVDTPGFGDAVNNTE
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB3 CWKPITDYVDQQFEQYFRDESGLNRKNIQDNRVHCCLYFISPFGHGLRPVDVGFMKALHE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 CWKPITDYVDQQFEQYFRDESGLNRKNIQDNRVHCCLYFISPFGHGLRPVDVGFMKALHE
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB3 KVNIVPLIAKADCLVPSEIRKLKERIREEIDKFGIHVYQFPECDSDEDEDFKQQDRELKE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 KVNIVPLIAKADCLVPSEIRKLKERIREEIDKFGIHVYQFPECDSDEDEDFKQQDRELKE
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB3 SAPFAVIGSNTVVEAKGQRVRGRLYPWGIVEVENQAHCDFVKLRNMLIRTHMHDLKDVTC
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 SAPFAVIGSNTVVEAKGQRVRGRLYPWGIVEVENQAHCDFVKLRNMLIRTHMHDLKDVTC
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KB3 DVHYENYRAHCIQQMTSKLTQDSRMESPIPILPLPTPDAETEKLIRMKDEELRRMQEMLQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 DVHYENYRAHCIQQMTSKLTQDSRMESPIPILPLPTPDAETEKLIRMKDEELRRMQEMLQ
              310       320       330       340       350       360

                
pF1KB3 RMKQQMQDQ
       :::::::::
NP_002 RMKQQMQDQ
                

>>XP_006722014 (OMIM: 603696) PREDICTED: septin-4 isofor  (379 aa)
 initn: 1900 init1: 1724 opt: 1869  Z-score: 2025.0  bits: 383.4 E(85289): 4.7e-106
Smith-Waterman score: 1909; 76.4% identity (90.8% similar) in 368 aa overlap (12-368:11-377)

               10        20          30        40        50        
pF1KB3 MSTGLRYKSKLATPEDKQDI--DKQYVGFATLPNQVHRKSVKKGFDFTLMVAGESGLGKS
                  ..:::. .   ::.:::::::::::::::::::::::::::::::::::
XP_006  MDRSLGWQGNSVPEDRTEAGDDKEYVGFATLPNQVHRKSVKKGFDFTLMVAGESGLGKS
                10        20        30        40        50         

       60        70        80        90       100       110        
pF1KB3 TLVHSLFLTDLYKDRKLLSAEERISQTVEILKHTVDIEEKGVKLKLTIVDTPGFGDAVNN
       :::.::::::::.:::::.::::: ::::: ::.::::::::.:.:::::::::::::::
XP_006 TLVNSLFLTDLYRDRKLLGAEERIMQTVEITKHAVDIEEKGVRLRLTIVDTPGFGDAVNN
      60        70        80        90       100       110         

      120       130       140       150       160       170        
pF1KB3 TECWKPITDYVDQQFEQYFRDESGLNRKNIQDNRVHCCLYFISPFGHGLRPVDVGFMKAL
       ::::::...:.::::::::::::::::::::::::::::::::::::::::.:: :::::
XP_006 TECWKPVAEYIDQQFEQYFRDESGLNRKNIQDNRVHCCLYFISPFGHGLRPLDVEFMKAL
     120       130       140       150       160       170         

      180       190       200       210       220       230        
pF1KB3 HEKVNIVPLIAKADCLVPSEIRKLKERIREEIDKFGIHVYQFPECDSDEDEDFKQQDREL
       :..:::::..:::: :.: :. . :..:::::..:::..::::.:::::::::: ::. :
XP_006 HQRVNIVPILAKADTLTPPEVDHKKRKIREEIEHFGIKIYQFPDCDSDEDEDFKLQDQAL
     180       190       200       210       220       230         

      240       250       260       270       280       290        
pF1KB3 KESAPFAVIGSNTVVEAKGQRVRGRLYPWGIVEVENQAHCDFVKLRNMLIRTHMHDLKDV
       ::: :::::::::::::.:.:::::::::::::::: .::::::::.::.::::.:::::
XP_006 KESIPFAVIGSNTVVEARGRRVRGRLYPWGIVEVENPGHCDFVKLRTMLVRTHMQDLKDV
     240       250       260       270       280       290         

      300       310                320       330       340         
pF1KB3 TCDVHYENYRAHCIQQMT---------SKLTQDSRMESPIPILPLPTPDAETEKLIRMKD
       : ..:::::::.:::.::         .:::..:  . ::: .: :  : ::::::: ::
XP_006 TRETHYENYRAQCIQSMTRLVVKERNRNKLTRESGTDFPIPAVP-PGTDPETEKLIREKD
     300       310       320       330       340        350        

     350       360          
pF1KB3 EELRRMQEMLQRMKQQMQDQ 
       ::::::::::.....::..  
XP_006 EELRRMQEMLHKIQKQMKENY
      360       370         

>>NP_536341 (OMIM: 603696) septin-4 isoform 3 [Homo sapi  (459 aa)
 initn: 1900 init1: 1724 opt: 1869  Z-score: 2023.8  bits: 383.4 E(85289): 5.5e-106
Smith-Waterman score: 1909; 76.9% identity (91.2% similar) in 364 aa overlap (14-368:95-457)

                                10        20        30        40   
pF1KB3                  MSTGLRYKSKLATPEDKQDIDKQYVGFATLPNQVHRKSVKKGF
                                     : :... ::.::::::::::::::::::::
NP_536 PQSSDNQQYFCAPAPLSPSARPRSPWGKLDPYDSSEDDKEYVGFATLPNQVHRKSVKKGF
           70        80        90       100       110       120    

            50        60        70        80        90       100   
pF1KB3 DFTLMVAGESGLGKSTLVHSLFLTDLYKDRKLLSAEERISQTVEILKHTVDIEEKGVKLK
       ::::::::::::::::::.::::::::.:::::.::::: ::::: ::.::::::::.:.
NP_536 DFTLMVAGESGLGKSTLVNSLFLTDLYRDRKLLGAEERIMQTVEITKHAVDIEEKGVRLR
          130       140       150       160       170       180    

           110       120       130       140       150       160   
pF1KB3 LTIVDTPGFGDAVNNTECWKPITDYVDQQFEQYFRDESGLNRKNIQDNRVHCCLYFISPF
       :::::::::::::::::::::...:.::::::::::::::::::::::::::::::::::
NP_536 LTIVDTPGFGDAVNNTECWKPVAEYIDQQFEQYFRDESGLNRKNIQDNRVHCCLYFISPF
          190       200       210       220       230       240    

           170       180       190       200       210       220   
pF1KB3 GHGLRPVDVGFMKALHEKVNIVPLIAKADCLVPSEIRKLKERIREEIDKFGIHVYQFPEC
       ::::::.:: ::::::..:::::..:::: :.: :. . :..:::::..:::..::::.:
NP_536 GHGLRPLDVEFMKALHQRVNIVPILAKADTLTPPEVDHKKRKIREEIEHFGIKIYQFPDC
          250       260       270       280       290       300    

           230       240       250       260       270       280   
pF1KB3 DSDEDEDFKQQDRELKESAPFAVIGSNTVVEAKGQRVRGRLYPWGIVEVENQAHCDFVKL
       ::::::::: ::. :::: :::::::::::::.:.:::::::::::::::: .:::::::
NP_536 DSDEDEDFKLQDQALKESIPFAVIGSNTVVEARGRRVRGRLYPWGIVEVENPGHCDFVKL
          310       320       330       340       350       360    

           290       300       310                320       330    
pF1KB3 RNMLIRTHMHDLKDVTCDVHYENYRAHCIQQMT---------SKLTQDSRMESPIPILPL
       :.::.::::.:::::: ..:::::::.:::.::         .:::..:  . ::: .: 
NP_536 RTMLVRTHMQDLKDVTRETHYENYRAQCIQSMTRLVVKERNRNKLTRESGTDFPIPAVP-
          370       380       390       400       410       420    

          340       350       360          
pF1KB3 PTPDAETEKLIRMKDEELRRMQEMLQRMKQQMQDQ 
       :  : ::::::: ::::::::::::.....::..  
NP_536 PGTDPETEKLIREKDEELRRMQEMLHKIQKQMKENY
           430       440       450         

>>NP_001185642 (OMIM: 603696) septin-4 isoform 4 [Homo s  (470 aa)
 initn: 1900 init1: 1724 opt: 1869  Z-score: 2023.6  bits: 383.4 E(85289): 5.6e-106
Smith-Waterman score: 1909; 76.9% identity (91.2% similar) in 364 aa overlap (14-368:106-468)

                                10        20        30        40   
pF1KB3                  MSTGLRYKSKLATPEDKQDIDKQYVGFATLPNQVHRKSVKKGF
                                     : :... ::.::::::::::::::::::::
NP_001 PQSSDNQQYFCAPAPLSPSARPRSPWGKLDPYDSSEDDKEYVGFATLPNQVHRKSVKKGF
          80        90       100       110       120       130     

            50        60        70        80        90       100   
pF1KB3 DFTLMVAGESGLGKSTLVHSLFLTDLYKDRKLLSAEERISQTVEILKHTVDIEEKGVKLK
       ::::::::::::::::::.::::::::.:::::.::::: ::::: ::.::::::::.:.
NP_001 DFTLMVAGESGLGKSTLVNSLFLTDLYRDRKLLGAEERIMQTVEITKHAVDIEEKGVRLR
         140       150       160       170       180       190     

           110       120       130       140       150       160   
pF1KB3 LTIVDTPGFGDAVNNTECWKPITDYVDQQFEQYFRDESGLNRKNIQDNRVHCCLYFISPF
       :::::::::::::::::::::...:.::::::::::::::::::::::::::::::::::
NP_001 LTIVDTPGFGDAVNNTECWKPVAEYIDQQFEQYFRDESGLNRKNIQDNRVHCCLYFISPF
         200       210       220       230       240       250     

           170       180       190       200       210       220   
pF1KB3 GHGLRPVDVGFMKALHEKVNIVPLIAKADCLVPSEIRKLKERIREEIDKFGIHVYQFPEC
       ::::::.:: ::::::..:::::..:::: :.: :. . :..:::::..:::..::::.:
NP_001 GHGLRPLDVEFMKALHQRVNIVPILAKADTLTPPEVDHKKRKIREEIEHFGIKIYQFPDC
         260       270       280       290       300       310     

           230       240       250       260       270       280   
pF1KB3 DSDEDEDFKQQDRELKESAPFAVIGSNTVVEAKGQRVRGRLYPWGIVEVENQAHCDFVKL
       ::::::::: ::. :::: :::::::::::::.:.:::::::::::::::: .:::::::
NP_001 DSDEDEDFKLQDQALKESIPFAVIGSNTVVEARGRRVRGRLYPWGIVEVENPGHCDFVKL
         320       330       340       350       360       370     

           290       300       310                320       330    
pF1KB3 RNMLIRTHMHDLKDVTCDVHYENYRAHCIQQMT---------SKLTQDSRMESPIPILPL
       :.::.::::.:::::: ..:::::::.:::.::         .:::..:  . ::: .: 
NP_001 RTMLVRTHMQDLKDVTRETHYENYRAQCIQSMTRLVVKERNRNKLTRESGTDFPIPAVP-
         380       390       400       410       420       430     

          340       350       360          
pF1KB3 PTPDAETEKLIRMKDEELRRMQEMLQRMKQQMQDQ 
       :  : ::::::: ::::::::::::.....::..  
NP_001 PGTDPETEKLIREKDEELRRMQEMLHKIQKQMKENY
          440       450       460       470

>>NP_004565 (OMIM: 603696) septin-4 isoform 1 [Homo sapi  (478 aa)
 initn: 1900 init1: 1724 opt: 1869  Z-score: 2023.5  bits: 383.4 E(85289): 5.7e-106
Smith-Waterman score: 1909; 76.9% identity (91.2% similar) in 364 aa overlap (14-368:114-476)

                                10        20        30        40   
pF1KB3                  MSTGLRYKSKLATPEDKQDIDKQYVGFATLPNQVHRKSVKKGF
                                     : :... ::.::::::::::::::::::::
NP_004 PQSSDNQQYFCAPAPLSPSARPRSPWGKLDPYDSSEDDKEYVGFATLPNQVHRKSVKKGF
            90       100       110       120       130       140   

            50        60        70        80        90       100   
pF1KB3 DFTLMVAGESGLGKSTLVHSLFLTDLYKDRKLLSAEERISQTVEILKHTVDIEEKGVKLK
       ::::::::::::::::::.::::::::.:::::.::::: ::::: ::.::::::::.:.
NP_004 DFTLMVAGESGLGKSTLVNSLFLTDLYRDRKLLGAEERIMQTVEITKHAVDIEEKGVRLR
           150       160       170       180       190       200   

           110       120       130       140       150       160   
pF1KB3 LTIVDTPGFGDAVNNTECWKPITDYVDQQFEQYFRDESGLNRKNIQDNRVHCCLYFISPF
       :::::::::::::::::::::...:.::::::::::::::::::::::::::::::::::
NP_004 LTIVDTPGFGDAVNNTECWKPVAEYIDQQFEQYFRDESGLNRKNIQDNRVHCCLYFISPF
           210       220       230       240       250       260   

           170       180       190       200       210       220   
pF1KB3 GHGLRPVDVGFMKALHEKVNIVPLIAKADCLVPSEIRKLKERIREEIDKFGIHVYQFPEC
       ::::::.:: ::::::..:::::..:::: :.: :. . :..:::::..:::..::::.:
NP_004 GHGLRPLDVEFMKALHQRVNIVPILAKADTLTPPEVDHKKRKIREEIEHFGIKIYQFPDC
           270       280       290       300       310       320   

           230       240       250       260       270       280   
pF1KB3 DSDEDEDFKQQDRELKESAPFAVIGSNTVVEAKGQRVRGRLYPWGIVEVENQAHCDFVKL
       ::::::::: ::. :::: :::::::::::::.:.:::::::::::::::: .:::::::
NP_004 DSDEDEDFKLQDQALKESIPFAVIGSNTVVEARGRRVRGRLYPWGIVEVENPGHCDFVKL
           330       340       350       360       370       380   

           290       300       310                320       330    
pF1KB3 RNMLIRTHMHDLKDVTCDVHYENYRAHCIQQMT---------SKLTQDSRMESPIPILPL
       :.::.::::.:::::: ..:::::::.:::.::         .:::..:  . ::: .: 
NP_004 RTMLVRTHMQDLKDVTRETHYENYRAQCIQSMTRLVVKERNRNKLTRESGTDFPIPAVP-
           390       400       410       420       430       440   

          340       350       360          
pF1KB3 PTPDAETEKLIRMKDEELRRMQEMLQRMKQQMQDQ 
       :  : ::::::: ::::::::::::.....::..  
NP_004 PGTDPETEKLIREKDEELRRMQEMLHKIQKQMKENY
            450       460       470        

>>XP_006722012 (OMIM: 603696) PREDICTED: septin-4 isofor  (483 aa)
 initn: 1900 init1: 1724 opt: 1869  Z-score: 2023.5  bits: 383.4 E(85289): 5.7e-106
Smith-Waterman score: 1909; 76.9% identity (91.2% similar) in 364 aa overlap (14-368:119-481)

                                10        20        30        40   
pF1KB3                  MSTGLRYKSKLATPEDKQDIDKQYVGFATLPNQVHRKSVKKGF
                                     : :... ::.::::::::::::::::::::
XP_006 PQSSDNQQYFCAPAPLSPSARPRSPWGKLDPYDSSEDDKEYVGFATLPNQVHRKSVKKGF
       90       100       110       120       130       140        

            50        60        70        80        90       100   
pF1KB3 DFTLMVAGESGLGKSTLVHSLFLTDLYKDRKLLSAEERISQTVEILKHTVDIEEKGVKLK
       ::::::::::::::::::.::::::::.:::::.::::: ::::: ::.::::::::.:.
XP_006 DFTLMVAGESGLGKSTLVNSLFLTDLYRDRKLLGAEERIMQTVEITKHAVDIEEKGVRLR
      150       160       170       180       190       200        

           110       120       130       140       150       160   
pF1KB3 LTIVDTPGFGDAVNNTECWKPITDYVDQQFEQYFRDESGLNRKNIQDNRVHCCLYFISPF
       :::::::::::::::::::::...:.::::::::::::::::::::::::::::::::::
XP_006 LTIVDTPGFGDAVNNTECWKPVAEYIDQQFEQYFRDESGLNRKNIQDNRVHCCLYFISPF
      210       220       230       240       250       260        

           170       180       190       200       210       220   
pF1KB3 GHGLRPVDVGFMKALHEKVNIVPLIAKADCLVPSEIRKLKERIREEIDKFGIHVYQFPEC
       ::::::.:: ::::::..:::::..:::: :.: :. . :..:::::..:::..::::.:
XP_006 GHGLRPLDVEFMKALHQRVNIVPILAKADTLTPPEVDHKKRKIREEIEHFGIKIYQFPDC
      270       280       290       300       310       320        

           230       240       250       260       270       280   
pF1KB3 DSDEDEDFKQQDRELKESAPFAVIGSNTVVEAKGQRVRGRLYPWGIVEVENQAHCDFVKL
       ::::::::: ::. :::: :::::::::::::.:.:::::::::::::::: .:::::::
XP_006 DSDEDEDFKLQDQALKESIPFAVIGSNTVVEARGRRVRGRLYPWGIVEVENPGHCDFVKL
      330       340       350       360       370       380        

           290       300       310                320       330    
pF1KB3 RNMLIRTHMHDLKDVTCDVHYENYRAHCIQQMT---------SKLTQDSRMESPIPILPL
       :.::.::::.:::::: ..:::::::.:::.::         .:::..:  . ::: .: 
XP_006 RTMLVRTHMQDLKDVTRETHYENYRAQCIQSMTRLVVKERNRNKLTRESGTDFPIPAVP-
      390       400       410       420       430       440        

          340       350       360          
pF1KB3 PTPDAETEKLIRMKDEELRRMQEMLQRMKQQMQDQ 
       :  : ::::::: ::::::::::::.....::..  
XP_006 PGTDPETEKLIREKDEELRRMQEMLHKIQKQMKENY
       450       460       470       480   

>>NP_001243711 (OMIM: 603696) septin-4 isoform 5 [Homo s  (493 aa)
 initn: 1900 init1: 1724 opt: 1869  Z-score: 2023.3  bits: 383.4 E(85289): 5.8e-106
Smith-Waterman score: 1909; 76.9% identity (91.2% similar) in 364 aa overlap (14-368:129-491)

                                10        20        30        40   
pF1KB3                  MSTGLRYKSKLATPEDKQDIDKQYVGFATLPNQVHRKSVKKGF
                                     : :... ::.::::::::::::::::::::
NP_001 PQSSDNQQYFCAPAPLSPSARPRSPWGKLDPYDSSEDDKEYVGFATLPNQVHRKSVKKGF
      100       110       120       130       140       150        

            50        60        70        80        90       100   
pF1KB3 DFTLMVAGESGLGKSTLVHSLFLTDLYKDRKLLSAEERISQTVEILKHTVDIEEKGVKLK
       ::::::::::::::::::.::::::::.:::::.::::: ::::: ::.::::::::.:.
NP_001 DFTLMVAGESGLGKSTLVNSLFLTDLYRDRKLLGAEERIMQTVEITKHAVDIEEKGVRLR
      160       170       180       190       200       210        

           110       120       130       140       150       160   
pF1KB3 LTIVDTPGFGDAVNNTECWKPITDYVDQQFEQYFRDESGLNRKNIQDNRVHCCLYFISPF
       :::::::::::::::::::::...:.::::::::::::::::::::::::::::::::::
NP_001 LTIVDTPGFGDAVNNTECWKPVAEYIDQQFEQYFRDESGLNRKNIQDNRVHCCLYFISPF
      220       230       240       250       260       270        

           170       180       190       200       210       220   
pF1KB3 GHGLRPVDVGFMKALHEKVNIVPLIAKADCLVPSEIRKLKERIREEIDKFGIHVYQFPEC
       ::::::.:: ::::::..:::::..:::: :.: :. . :..:::::..:::..::::.:
NP_001 GHGLRPLDVEFMKALHQRVNIVPILAKADTLTPPEVDHKKRKIREEIEHFGIKIYQFPDC
      280       290       300       310       320       330        

           230       240       250       260       270       280   
pF1KB3 DSDEDEDFKQQDRELKESAPFAVIGSNTVVEAKGQRVRGRLYPWGIVEVENQAHCDFVKL
       ::::::::: ::. :::: :::::::::::::.:.:::::::::::::::: .:::::::
NP_001 DSDEDEDFKLQDQALKESIPFAVIGSNTVVEARGRRVRGRLYPWGIVEVENPGHCDFVKL
      340       350       360       370       380       390        

           290       300       310                320       330    
pF1KB3 RNMLIRTHMHDLKDVTCDVHYENYRAHCIQQMT---------SKLTQDSRMESPIPILPL
       :.::.::::.:::::: ..:::::::.:::.::         .:::..:  . ::: .: 
NP_001 RTMLVRTHMQDLKDVTRETHYENYRAQCIQSMTRLVVKERNRNKLTRESGTDFPIPAVP-
      400       410       420       430       440       450        

          340       350       360          
pF1KB3 PTPDAETEKLIRMKDEELRRMQEMLQRMKQQMQDQ 
       :  : ::::::: ::::::::::::.....::..  
NP_001 PGTDPETEKLIREKDEELRRMQEMLHKIQKQMKENY
       460       470       480       490   

>>XP_006722013 (OMIM: 603696) PREDICTED: septin-4 isofor  (384 aa)
 initn: 1900 init1: 1724 opt: 1858  Z-score: 2013.0  bits: 381.2 E(85289): 2.2e-105
Smith-Waterman score: 1898; 74.8% identity (88.9% similar) in 377 aa overlap (2-368:7-382)

                    10        20         30        40        50    
pF1KB3      MSTGLRYKSKLATPEDKQDID-KQYVGFATLPNQVHRKSVKKGFDFTLMVAGESG
             : : :  .  . : .   .: :.:::::::::::::::::::::::::::::::
XP_006 MGPVPTSFGKRRGGPQTLPASPGGMDDKEYVGFATLPNQVHRKSVKKGFDFTLMVAGESG
               10        20        30        40        50        60

           60        70        80        90       100       110    
pF1KB3 LGKSTLVHSLFLTDLYKDRKLLSAEERISQTVEILKHTVDIEEKGVKLKLTIVDTPGFGD
       :::::::.::::::::.:::::.::::: ::::: ::.::::::::.:.:::::::::::
XP_006 LGKSTLVNSLFLTDLYRDRKLLGAEERIMQTVEITKHAVDIEEKGVRLRLTIVDTPGFGD
               70        80        90       100       110       120

          120       130       140       150       160       170    
pF1KB3 AVNNTECWKPITDYVDQQFEQYFRDESGLNRKNIQDNRVHCCLYFISPFGHGLRPVDVGF
       ::::::::::...:.::::::::::::::::::::::::::::::::::::::::.:: :
XP_006 AVNNTECWKPVAEYIDQQFEQYFRDESGLNRKNIQDNRVHCCLYFISPFGHGLRPLDVEF
              130       140       150       160       170       180

          180       190       200       210       220       230    
pF1KB3 MKALHEKVNIVPLIAKADCLVPSEIRKLKERIREEIDKFGIHVYQFPECDSDEDEDFKQQ
       :::::..:::::..:::: :.: :. . :..:::::..:::..::::.:::::::::: :
XP_006 MKALHQRVNIVPILAKADTLTPPEVDHKKRKIREEIEHFGIKIYQFPDCDSDEDEDFKLQ
              190       200       210       220       230       240

          240       250       260       270       280       290    
pF1KB3 DRELKESAPFAVIGSNTVVEAKGQRVRGRLYPWGIVEVENQAHCDFVKLRNMLIRTHMHD
       :. :::: :::::::::::::.:.:::::::::::::::: .::::::::.::.::::.:
XP_006 DQALKESIPFAVIGSNTVVEARGRRVRGRLYPWGIVEVENPGHCDFVKLRTMLVRTHMQD
              250       260       270       280       290       300

          300       310                320       330       340     
pF1KB3 LKDVTCDVHYENYRAHCIQQMT---------SKLTQDSRMESPIPILPLPTPDAETEKLI
       ::::: ..:::::::.:::.::         .:::..:  . ::: .: :  : ::::::
XP_006 LKDVTRETHYENYRAQCIQSMTRLVVKERNRNKLTRESGTDFPIPAVP-PGTDPETEKLI
              310       320       330       340        350         

         350       360          
pF1KB3 RMKDEELRRMQEMLQRMKQQMQDQ 
       : ::::::::::::.....::..  
XP_006 REKDEELRRMQEMLHKIQKQMKENY
     360       370       380    

>>XP_006722015 (OMIM: 603696) PREDICTED: septin-4 isofor  (360 aa)
 initn: 1900 init1: 1724 opt: 1855  Z-score: 2010.1  bits: 380.5 E(85289): 3.2e-105
Smith-Waterman score: 1895; 77.9% identity (91.6% similar) in 357 aa overlap (21-368:3-358)

               10        20        30        40        50        60
pF1KB3 MSTGLRYKSKLATPEDKQDIDKQYVGFATLPNQVHRKSVKKGFDFTLMVAGESGLGKSTL
                           ::.:::::::::::::::::::::::::::::::::::::
XP_006                   MDDKEYVGFATLPNQVHRKSVKKGFDFTLMVAGESGLGKSTL
                                 10        20        30        40  

               70        80        90       100       110       120
pF1KB3 VHSLFLTDLYKDRKLLSAEERISQTVEILKHTVDIEEKGVKLKLTIVDTPGFGDAVNNTE
       :.::::::::.:::::.::::: ::::: ::.::::::::.:.:::::::::::::::::
XP_006 VNSLFLTDLYRDRKLLGAEERIMQTVEITKHAVDIEEKGVRLRLTIVDTPGFGDAVNNTE
             50        60        70        80        90       100  

              130       140       150       160       170       180
pF1KB3 CWKPITDYVDQQFEQYFRDESGLNRKNIQDNRVHCCLYFISPFGHGLRPVDVGFMKALHE
       ::::...:.::::::::::::::::::::::::::::::::::::::::.:: ::::::.
XP_006 CWKPVAEYIDQQFEQYFRDESGLNRKNIQDNRVHCCLYFISPFGHGLRPLDVEFMKALHQ
            110       120       130       140       150       160  

              190       200       210       220       230       240
pF1KB3 KVNIVPLIAKADCLVPSEIRKLKERIREEIDKFGIHVYQFPECDSDEDEDFKQQDRELKE
       .:::::..:::: :.: :. . :..:::::..:::..::::.:::::::::: ::. :::
XP_006 RVNIVPILAKADTLTPPEVDHKKRKIREEIEHFGIKIYQFPDCDSDEDEDFKLQDQALKE
            170       180       190       200       210       220  

              250       260       270       280       290       300
pF1KB3 SAPFAVIGSNTVVEAKGQRVRGRLYPWGIVEVENQAHCDFVKLRNMLIRTHMHDLKDVTC
       : :::::::::::::.:.:::::::::::::::: .::::::::.::.::::.:::::: 
XP_006 SIPFAVIGSNTVVEARGRRVRGRLYPWGIVEVENPGHCDFVKLRTMLVRTHMQDLKDVTR
            230       240       250       260       270       280  

              310                320       330       340       350 
pF1KB3 DVHYENYRAHCIQQMT---------SKLTQDSRMESPIPILPLPTPDAETEKLIRMKDEE
       ..:::::::.:::.::         .:::..:  . ::: .: :  : ::::::: ::::
XP_006 ETHYENYRAQCIQSMTRLVVKERNRNKLTRESGTDFPIPAVP-PGTDPETEKLIREKDEE
            290       300       310       320        330       340 

             360          
pF1KB3 LRRMQEMLQRMKQQMQDQ 
       ::::::::.....::..  
XP_006 LRRMQEMLHKIQKQMKENY
             350       360

>>NP_001009939 (OMIM: 602724) septin-5 isoform 2 [Homo s  (346 aa)
 initn: 1699 init1: 1699 opt: 1699  Z-score: 1841.9  bits: 349.3 E(85289): 7.5e-96
Smith-Waterman score: 1699; 99.6% identity (100.0% similar) in 254 aa overlap (18-271:27-280)

                        10        20        30        40        50 
pF1KB3          MSTGLRYKSKLATPEDKQDIDKQYVGFATLPNQVHRKSVKKGFDFTLMVAG
                                 .:::::::::::::::::::::::::::::::::
NP_001 MDSLAAPQDRLVEQLLSPRTQAQRRLKDIDKQYVGFATLPNQVHRKSVKKGFDFTLMVAG
               10        20        30        40        50        60

              60        70        80        90       100       110 
pF1KB3 ESGLGKSTLVHSLFLTDLYKDRKLLSAEERISQTVEILKHTVDIEEKGVKLKLTIVDTPG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ESGLGKSTLVHSLFLTDLYKDRKLLSAEERISQTVEILKHTVDIEEKGVKLKLTIVDTPG
               70        80        90       100       110       120

             120       130       140       150       160       170 
pF1KB3 FGDAVNNTECWKPITDYVDQQFEQYFRDESGLNRKNIQDNRVHCCLYFISPFGHGLRPVD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FGDAVNNTECWKPITDYVDQQFEQYFRDESGLNRKNIQDNRVHCCLYFISPFGHGLRPVD
              130       140       150       160       170       180

             180       190       200       210       220       230 
pF1KB3 VGFMKALHEKVNIVPLIAKADCLVPSEIRKLKERIREEIDKFGIHVYQFPECDSDEDEDF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VGFMKALHEKVNIVPLIAKADCLVPSEIRKLKERIREEIDKFGIHVYQFPECDSDEDEDF
              190       200       210       220       230       240

             240       250       260       270       280       290 
pF1KB3 KQQDRELKESAPFAVIGSNTVVEAKGQRVRGRLYPWGIVEVENQAHCDFVKLRNMLIRTH
       ::::::::::::::::::::::::::::::::::::::::                    
NP_001 KQQDRELKESAPFAVIGSNTVVEAKGQRVRGRLYPWGIVEGALRLREAAQHAHPHAYARP
              250       260       270       280       290       300

             300       310       320       330       340       350 
pF1KB3 MHDLKDVTCDVHYENYRAHCIQQMTSKLTQDSRMESPIPILPLPTPDAETEKLIRMKDEE
                                                                   
NP_001 QGRDVRRALRELPRALHPADDQQTDPGQPHGEPHPDPAAAHPGRRD              
              310       320       330       340                    




369 residues in 1 query   sequences
60827320 residues in 85289 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Fri Nov  4 02:42:45 2016 done: Fri Nov  4 02:42:47 2016
 Total Scan time:  8.330 Total Display time:  0.030

Function used was FASTA [36.3.4 Apr, 2011]
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