Result of FASTA (omim) for pF1KB1226
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KB1226, 1222 aa
  1>>>pF1KB1226 1222 - 1222 aa - 1222 aa
Library: /omim/omim.rfq.tfa
  60827320 residues in 85289 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 5.9689+/-0.00051; mu= 19.1105+/- 0.032
 mean_var=76.8313+/-15.227, 0's: 0 Z-trim(108.7): 18  B-trim: 498 in 1/50
 Lambda= 0.146320
 statistics sampled from 16811 (16822) to 16811 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.542), E-opt: 0.2 (0.197), width:  16
 Scan time: 13.060

The best scores are:                                      opt bits E(85289)
NP_775885 (OMIM: 609158) nodal modulator 2 isoform (1222) 8017 1703.0       0
NP_001004060 (OMIM: 609158) nodal modulator 2 isof (1267) 8017 1703.1       0
NP_001004067 (OMIM: 609159) nodal modulator 3 prec (1222) 7996 1698.6       0
XP_005255375 (OMIM: 609159) PREDICTED: nodal modul (1267) 7996 1698.6       0
NP_055102 (OMIM: 609157) nodal modulator 1 precurs (1222) 7976 1694.4       0
XP_016855194 (OMIM: 609159) PREDICTED: nodal modul ( 811) 5152 1098.2       0
XP_016878645 (OMIM: 609158) PREDICTED: nodal modul ( 651) 3960 846.5       0


>>NP_775885 (OMIM: 609158) nodal modulator 2 isoform 2 p  (1222 aa)
 initn: 8017 init1: 8017 opt: 8017  Z-score: 9138.7  bits: 1703.0 E(85289):    0
Smith-Waterman score: 8017; 99.9% identity (99.9% similar) in 1222 aa overlap (1-1222:1-1222)

               10        20        30        40        50        60
pF1KB1 MLVGQGAGLLGPAVVTAAVVLLLSGVGPAHGSEDIVVGCGGFVKSDVEINYSLIEIKLYT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_775 MLVGQGAGLLGPAVVTAAVVLLLSGVGPAHGSEDIVVGCGGFVKSDVEINYSLIEIKLYT
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB1 KHGTLKYQTDCAPNNGYFMIPLYDKGDFILKIEPPLGWSFEPTTVELHVDGVSDICTKGG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_775 KHGTLKYQTDCAPNNGYFMIPLYDKGDFILKIEPPLGWSFEPTTVELHVDGVSDICTKGG
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB1 DINFVFTGFSVNGKVLSKGQPLGPAGVQVSLRNTGTEAKIQSTVTQPGGKFAFFKVLPGD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_775 DINFVFTGFSVNGKVLSKGQPLGPAGVQVSLRNTGTEAKIQSTVTQPGGKFAFFKVLPGD
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB1 YEILATHPTWALKEASTTVRVTNSNANAASPLIVAGYNVSGSVRSDGEPMKGVKFLLFSS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_775 YEILATHPTWALKEASTTVRVTNSNANAASPLIVAGYNVSGSVRSDGEPMKGVKFLLFSS
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB1 LVTKEDVLGCNVSPVPGFQPQDESLVYLCYTVSREDGSFSFYSLPSGGYTVIPFYRGERI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_775 LVTKEDVLGCNVSPVPGFQPQDESLVYLCYTVSREDGSFSFYSLPSGGYTVIPFYRGERI
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KB1 TFDVAPSRLDFTVEHDSLKIEPVFHVMGFSVTGRVLNGPEGDGVPEAVVTLNNQIKVKTK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_775 TFDVAPSRLDFTVEHDSLKIEPVFHVMGFSVTGRVLNGPEGDGVPEAVVTLNNQIKVKTK
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KB1 ADGSFRLENITTGTYTIHAQKEHLYFETVTIKIAPNTPQLADIVATGFSVCGRISIIRFP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_775 ADGSFRLENITTGTYTIHAQKEHLYFETVTIKIAPNTPQLADIVATGFSVCGRISIIRFP
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KB1 DTVKQMNKYKVVLSSQDKDKSLVTVETDAHGSFCFKAKPGTYKVQVMVPEAETRAGLTLK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_775 DTVKQMNKYKVVLSSQDKDKSLVTVETDAHGSFCFKAKPGTYKVQVMVPEAETRAGLTLK
              430       440       450       460       470       480

              490       500       510       520       530       540
pF1KB1 PQTFPLTVTDRPVMDVAFVQFLASVSGKVSCLDTCGDLLVTLQSLSRQGEKRSLQLSGKV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_775 PQTFPLTVTDRPVMDVAFVQFLASVSGKVSCLDTCGDLLVTLQSLSRQGEKRSLQLSGKV
              490       500       510       520       530       540

              550       560       570       580       590       600
pF1KB1 NAMTFTFDNVLPGKYKISIMHEDWCWKNKSLEVEVLEDDVSAVEFRQTGYMLRCSLSHAI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_775 NAMTFTFDNVLPGKYKISIMHEDWCWKNKSLEVEVLEDDVSAVEFRQTGYMLRCSLSHAI
              550       560       570       580       590       600

              610       620       630       640       650       660
pF1KB1 TLEFYQDGNGRENVGIYNLSKGVNRFCLSKPGVYKVTPRSCHRFEQAFYTYDTSSPSILT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_775 TLEFYQDGNGRENVGIYNLSKGVNRFCLSKPGVYKVTPRSCHRFEQAFYTYDTSSPSILT
              610       620       630       640       650       660

              670       680       690       700       710       720
pF1KB1 LTAIRHHVLGTITTDKMMDVTVTIKSSIDSEPALVLGPLKSVQELRREQQLAEIEARRQE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_775 LTAIRHHVLGTITTDKMMDVTVTIKSSIDSEPALVLGPLKSVQELRREQQLAEIEARRQE
              670       680       690       700       710       720

              730       740       750       760       770       780
pF1KB1 REKNGNEEGEERMTKPSVQEMVDELQGPFSYDFSYWARSGEKITVTPSSKELLFYPPSME
       :::::::::::::::: :::::::::::::::::::::::::::::::::::::::::::
NP_775 REKNGNEEGEERMTKPPVQEMVDELQGPFSYDFSYWARSGEKITVTPSSKELLFYPPSME
              730       740       750       760       770       780

              790       800       810       820       830       840
pF1KB1 AVVSGESCPGKLIEIHGKAGLFLEGQIHPELEGVEIVISEKGASSPLITVFTDDKGAYSV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_775 AVVSGESCPGKLIEIHGKAGLFLEGQIHPELEGVEIVISEKGASSPLITVFTDDKGAYSV
              790       800       810       820       830       840

              850       860       870       880       890       900
pF1KB1 GPLHSDLEYTVTSQKEGYVLTAVEGTIGDFKAYALAGVSFEIKAEDDQPLPGVLLSLSGG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_775 GPLHSDLEYTVTSQKEGYVLTAVEGTIGDFKAYALAGVSFEIKAEDDQPLPGVLLSLSGG
              850       860       870       880       890       900

              910       920       930       940       950       960
pF1KB1 LFRSNLLTQDNGILTFSNLSPGQYYFKPMMKEFRFEPSSQMIEVQEGQNLKITITGYRTA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_775 LFRSNLLTQDNGILTFSNLSPGQYYFKPMMKEFRFEPSSQMIEVQEGQNLKITITGYRTA
              910       920       930       940       950       960

              970       980       990      1000      1010      1020
pF1KB1 YSCYGTVSSLNGEPEQGVAMEAVGQNDCSIYGEDTVTDEEGKFRLRGLLPGCVYHVQLKA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_775 YSCYGTVSSLNGEPEQGVAMEAVGQNDCSIYGEDTVTDEEGKFRLRGLLPGCVYHVQLKA
              970       980       990      1000      1010      1020

             1030      1040      1050      1060      1070      1080
pF1KB1 EGNDHIERALPHHRVIEVGNNDIDDVNIIVFRQINQFDLSGNVITSSEYLPTLWVKLYKS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_775 EGNDHIERALPHHRVIEVGNNDIDDVNIIVFRQINQFDLSGNVITSSEYLPTLWVKLYKS
             1030      1040      1050      1060      1070      1080

             1090      1100      1110      1120      1130      1140
pF1KB1 ENLDNPIQTVSLGQSLFFHFPPLLRDGENYVVLLDSTLPRSQYDYILPQVSFTAVGYHKH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_775 ENLDNPIQTVSLGQSLFFHFPPLLRDGENYVVLLDSTLPRSQYDYILPQVSFTAVGYHKH
             1090      1100      1110      1120      1130      1140

             1150      1160      1170      1180      1190      1200
pF1KB1 ITLIFNPTRKLPEQDIAQGSYIALPLTLLVLLAGYNHDKLIPLLLQLTSRLQGVGALGQA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_775 ITLIFNPTRKLPEQDIAQGSYIALPLTLLVLLAGYNHDKLIPLLLQLTSRLQGVGALGQA
             1150      1160      1170      1180      1190      1200

             1210      1220  
pF1KB1 ASDNSGPEDAKRQAKKQKTRRT
       ::::::::::::::::::::::
NP_775 ASDNSGPEDAKRQAKKQKTRRT
             1210      1220  

>>NP_001004060 (OMIM: 609158) nodal modulator 2 isoform   (1267 aa)
 initn: 8017 init1: 8017 opt: 8017  Z-score: 9138.4  bits: 1703.1 E(85289):    0
Smith-Waterman score: 8017; 99.9% identity (99.9% similar) in 1222 aa overlap (1-1222:1-1222)

               10        20        30        40        50        60
pF1KB1 MLVGQGAGLLGPAVVTAAVVLLLSGVGPAHGSEDIVVGCGGFVKSDVEINYSLIEIKLYT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MLVGQGAGLLGPAVVTAAVVLLLSGVGPAHGSEDIVVGCGGFVKSDVEINYSLIEIKLYT
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB1 KHGTLKYQTDCAPNNGYFMIPLYDKGDFILKIEPPLGWSFEPTTVELHVDGVSDICTKGG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KHGTLKYQTDCAPNNGYFMIPLYDKGDFILKIEPPLGWSFEPTTVELHVDGVSDICTKGG
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB1 DINFVFTGFSVNGKVLSKGQPLGPAGVQVSLRNTGTEAKIQSTVTQPGGKFAFFKVLPGD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DINFVFTGFSVNGKVLSKGQPLGPAGVQVSLRNTGTEAKIQSTVTQPGGKFAFFKVLPGD
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB1 YEILATHPTWALKEASTTVRVTNSNANAASPLIVAGYNVSGSVRSDGEPMKGVKFLLFSS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 YEILATHPTWALKEASTTVRVTNSNANAASPLIVAGYNVSGSVRSDGEPMKGVKFLLFSS
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB1 LVTKEDVLGCNVSPVPGFQPQDESLVYLCYTVSREDGSFSFYSLPSGGYTVIPFYRGERI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LVTKEDVLGCNVSPVPGFQPQDESLVYLCYTVSREDGSFSFYSLPSGGYTVIPFYRGERI
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KB1 TFDVAPSRLDFTVEHDSLKIEPVFHVMGFSVTGRVLNGPEGDGVPEAVVTLNNQIKVKTK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TFDVAPSRLDFTVEHDSLKIEPVFHVMGFSVTGRVLNGPEGDGVPEAVVTLNNQIKVKTK
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KB1 ADGSFRLENITTGTYTIHAQKEHLYFETVTIKIAPNTPQLADIVATGFSVCGRISIIRFP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ADGSFRLENITTGTYTIHAQKEHLYFETVTIKIAPNTPQLADIVATGFSVCGRISIIRFP
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KB1 DTVKQMNKYKVVLSSQDKDKSLVTVETDAHGSFCFKAKPGTYKVQVMVPEAETRAGLTLK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DTVKQMNKYKVVLSSQDKDKSLVTVETDAHGSFCFKAKPGTYKVQVMVPEAETRAGLTLK
              430       440       450       460       470       480

              490       500       510       520       530       540
pF1KB1 PQTFPLTVTDRPVMDVAFVQFLASVSGKVSCLDTCGDLLVTLQSLSRQGEKRSLQLSGKV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PQTFPLTVTDRPVMDVAFVQFLASVSGKVSCLDTCGDLLVTLQSLSRQGEKRSLQLSGKV
              490       500       510       520       530       540

              550       560       570       580       590       600
pF1KB1 NAMTFTFDNVLPGKYKISIMHEDWCWKNKSLEVEVLEDDVSAVEFRQTGYMLRCSLSHAI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NAMTFTFDNVLPGKYKISIMHEDWCWKNKSLEVEVLEDDVSAVEFRQTGYMLRCSLSHAI
              550       560       570       580       590       600

              610       620       630       640       650       660
pF1KB1 TLEFYQDGNGRENVGIYNLSKGVNRFCLSKPGVYKVTPRSCHRFEQAFYTYDTSSPSILT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TLEFYQDGNGRENVGIYNLSKGVNRFCLSKPGVYKVTPRSCHRFEQAFYTYDTSSPSILT
              610       620       630       640       650       660

              670       680       690       700       710       720
pF1KB1 LTAIRHHVLGTITTDKMMDVTVTIKSSIDSEPALVLGPLKSVQELRREQQLAEIEARRQE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LTAIRHHVLGTITTDKMMDVTVTIKSSIDSEPALVLGPLKSVQELRREQQLAEIEARRQE
              670       680       690       700       710       720

              730       740       750       760       770       780
pF1KB1 REKNGNEEGEERMTKPSVQEMVDELQGPFSYDFSYWARSGEKITVTPSSKELLFYPPSME
       :::::::::::::::: :::::::::::::::::::::::::::::::::::::::::::
NP_001 REKNGNEEGEERMTKPPVQEMVDELQGPFSYDFSYWARSGEKITVTPSSKELLFYPPSME
              730       740       750       760       770       780

              790       800       810       820       830       840
pF1KB1 AVVSGESCPGKLIEIHGKAGLFLEGQIHPELEGVEIVISEKGASSPLITVFTDDKGAYSV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AVVSGESCPGKLIEIHGKAGLFLEGQIHPELEGVEIVISEKGASSPLITVFTDDKGAYSV
              790       800       810       820       830       840

              850       860       870       880       890       900
pF1KB1 GPLHSDLEYTVTSQKEGYVLTAVEGTIGDFKAYALAGVSFEIKAEDDQPLPGVLLSLSGG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GPLHSDLEYTVTSQKEGYVLTAVEGTIGDFKAYALAGVSFEIKAEDDQPLPGVLLSLSGG
              850       860       870       880       890       900

              910       920       930       940       950       960
pF1KB1 LFRSNLLTQDNGILTFSNLSPGQYYFKPMMKEFRFEPSSQMIEVQEGQNLKITITGYRTA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LFRSNLLTQDNGILTFSNLSPGQYYFKPMMKEFRFEPSSQMIEVQEGQNLKITITGYRTA
              910       920       930       940       950       960

              970       980       990      1000      1010      1020
pF1KB1 YSCYGTVSSLNGEPEQGVAMEAVGQNDCSIYGEDTVTDEEGKFRLRGLLPGCVYHVQLKA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 YSCYGTVSSLNGEPEQGVAMEAVGQNDCSIYGEDTVTDEEGKFRLRGLLPGCVYHVQLKA
              970       980       990      1000      1010      1020

             1030      1040      1050      1060      1070      1080
pF1KB1 EGNDHIERALPHHRVIEVGNNDIDDVNIIVFRQINQFDLSGNVITSSEYLPTLWVKLYKS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EGNDHIERALPHHRVIEVGNNDIDDVNIIVFRQINQFDLSGNVITSSEYLPTLWVKLYKS
             1030      1040      1050      1060      1070      1080

             1090      1100      1110      1120      1130      1140
pF1KB1 ENLDNPIQTVSLGQSLFFHFPPLLRDGENYVVLLDSTLPRSQYDYILPQVSFTAVGYHKH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ENLDNPIQTVSLGQSLFFHFPPLLRDGENYVVLLDSTLPRSQYDYILPQVSFTAVGYHKH
             1090      1100      1110      1120      1130      1140

             1150      1160      1170      1180      1190      1200
pF1KB1 ITLIFNPTRKLPEQDIAQGSYIALPLTLLVLLAGYNHDKLIPLLLQLTSRLQGVGALGQA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ITLIFNPTRKLPEQDIAQGSYIALPLTLLVLLAGYNHDKLIPLLLQLTSRLQGVGALGQA
             1150      1160      1170      1180      1190      1200

             1210      1220                                        
pF1KB1 ASDNSGPEDAKRQAKKQKTRRT                                      
       ::::::::::::::::::::::                                      
NP_001 ASDNSGPEDAKRQAKKQKTRRTLRLQEEFQLMWCLVPWRGTLGIHLFSSLPFASEILLET
             1210      1220      1230      1240      1250      1260

>>NP_001004067 (OMIM: 609159) nodal modulator 3 precurso  (1222 aa)
 initn: 7996 init1: 7996 opt: 7996  Z-score: 9114.7  bits: 1698.6 E(85289):    0
Smith-Waterman score: 7996; 99.7% identity (99.8% similar) in 1222 aa overlap (1-1222:1-1222)

               10        20        30        40        50        60
pF1KB1 MLVGQGAGLLGPAVVTAAVVLLLSGVGPAHGSEDIVVGCGGFVKSDVEINYSLIEIKLYT
       :::::::: :::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MLVGQGAGPLGPAVVTAAVVLLLSGVGPAHGSEDIVVGCGGFVKSDVEINYSLIEIKLYT
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB1 KHGTLKYQTDCAPNNGYFMIPLYDKGDFILKIEPPLGWSFEPTTVELHVDGVSDICTKGG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KHGTLKYQTDCAPNNGYFMIPLYDKGDFILKIEPPLGWSFEPTTVELHVDGVSDICTKGG
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB1 DINFVFTGFSVNGKVLSKGQPLGPAGVQVSLRNTGTEAKIQSTVTQPGGKFAFFKVLPGD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DINFVFTGFSVNGKVLSKGQPLGPAGVQVSLRNTGTEAKIQSTVTQPGGKFAFFKVLPGD
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB1 YEILATHPTWALKEASTTVRVTNSNANAASPLIVAGYNVSGSVRSDGEPMKGVKFLLFSS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 YEILATHPTWALKEASTTVRVTNSNANAASPLIVAGYNVSGSVRSDGEPMKGVKFLLFSS
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB1 LVTKEDVLGCNVSPVPGFQPQDESLVYLCYTVSREDGSFSFYSLPSGGYTVIPFYRGERI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LVTKEDVLGCNVSPVPGFQPQDESLVYLCYTVSREDGSFSFYSLPSGGYTVIPFYRGERI
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KB1 TFDVAPSRLDFTVEHDSLKIEPVFHVMGFSVTGRVLNGPEGDGVPEAVVTLNNQIKVKTK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TFDVAPSRLDFTVEHDSLKIEPVFHVMGFSVTGRVLNGPEGDGVPEAVVTLNNQIKVKTK
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KB1 ADGSFRLENITTGTYTIHAQKEHLYFETVTIKIAPNTPQLADIVATGFSVCGRISIIRFP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::.:::::::
NP_001 ADGSFRLENITTGTYTIHAQKEHLYFETVTIKIAPNTPQLADIVATGFSVCGQISIIRFP
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KB1 DTVKQMNKYKVVLSSQDKDKSLVTVETDAHGSFCFKAKPGTYKVQVMVPEAETRAGLTLK
       :::::::::::::::::::::::::::::::::::::.::::::::::::::::::::::
NP_001 DTVKQMNKYKVVLSSQDKDKSLVTVETDAHGSFCFKANPGTYKVQVMVPEAETRAGLTLK
              430       440       450       460       470       480

              490       500       510       520       530       540
pF1KB1 PQTFPLTVTDRPVMDVAFVQFLASVSGKVSCLDTCGDLLVTLQSLSRQGEKRSLQLSGKV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PQTFPLTVTDRPVMDVAFVQFLASVSGKVSCLDTCGDLLVTLQSLSRQGEKRSLQLSGKV
              490       500       510       520       530       540

              550       560       570       580       590       600
pF1KB1 NAMTFTFDNVLPGKYKISIMHEDWCWKNKSLEVEVLEDDVSAVEFRQTGYMLRCSLSHAI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NAMTFTFDNVLPGKYKISIMHEDWCWKNKSLEVEVLEDDVSAVEFRQTGYMLRCSLSHAI
              550       560       570       580       590       600

              610       620       630       640       650       660
pF1KB1 TLEFYQDGNGRENVGIYNLSKGVNRFCLSKPGVYKVTPRSCHRFEQAFYTYDTSSPSILT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TLEFYQDGNGRENVGIYNLSKGVNRFCLSKPGVYKVTPRSCHRFEQAFYTYDTSSPSILT
              610       620       630       640       650       660

              670       680       690       700       710       720
pF1KB1 LTAIRHHVLGTITTDKMMDVTVTIKSSIDSEPALVLGPLKSVQELRREQQLAEIEARRQE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LTAIRHHVLGTITTDKMMDVTVTIKSSIDSEPALVLGPLKSVQELRREQQLAEIEARRQE
              670       680       690       700       710       720

              730       740       750       760       770       780
pF1KB1 REKNGNEEGEERMTKPSVQEMVDELQGPFSYDFSYWARSGEKITVTPSSKELLFYPPSME
       :::::::::::::::: :::::::::::::::::::::::::::::::::::::::::::
NP_001 REKNGNEEGEERMTKPPVQEMVDELQGPFSYDFSYWARSGEKITVTPSSKELLFYPPSME
              730       740       750       760       770       780

              790       800       810       820       830       840
pF1KB1 AVVSGESCPGKLIEIHGKAGLFLEGQIHPELEGVEIVISEKGASSPLITVFTDDKGAYSV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AVVSGESCPGKLIEIHGKAGLFLEGQIHPELEGVEIVISEKGASSPLITVFTDDKGAYSV
              790       800       810       820       830       840

              850       860       870       880       890       900
pF1KB1 GPLHSDLEYTVTSQKEGYVLTAVEGTIGDFKAYALAGVSFEIKAEDDQPLPGVLLSLSGG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GPLHSDLEYTVTSQKEGYVLTAVEGTIGDFKAYALAGVSFEIKAEDDQPLPGVLLSLSGG
              850       860       870       880       890       900

              910       920       930       940       950       960
pF1KB1 LFRSNLLTQDNGILTFSNLSPGQYYFKPMMKEFRFEPSSQMIEVQEGQNLKITITGYRTA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LFRSNLLTQDNGILTFSNLSPGQYYFKPMMKEFRFEPSSQMIEVQEGQNLKITITGYRTA
              910       920       930       940       950       960

              970       980       990      1000      1010      1020
pF1KB1 YSCYGTVSSLNGEPEQGVAMEAVGQNDCSIYGEDTVTDEEGKFRLRGLLPGCVYHVQLKA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 YSCYGTVSSLNGEPEQGVAMEAVGQNDCSIYGEDTVTDEEGKFRLRGLLPGCVYHVQLKA
              970       980       990      1000      1010      1020

             1030      1040      1050      1060      1070      1080
pF1KB1 EGNDHIERALPHHRVIEVGNNDIDDVNIIVFRQINQFDLSGNVITSSEYLPTLWVKLYKS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EGNDHIERALPHHRVIEVGNNDIDDVNIIVFRQINQFDLSGNVITSSEYLPTLWVKLYKS
             1030      1040      1050      1060      1070      1080

             1090      1100      1110      1120      1130      1140
pF1KB1 ENLDNPIQTVSLGQSLFFHFPPLLRDGENYVVLLDSTLPRSQYDYILPQVSFTAVGYHKH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ENLDNPIQTVSLGQSLFFHFPPLLRDGENYVVLLDSTLPRSQYDYILPQVSFTAVGYHKH
             1090      1100      1110      1120      1130      1140

             1150      1160      1170      1180      1190      1200
pF1KB1 ITLIFNPTRKLPEQDIAQGSYIALPLTLLVLLAGYNHDKLIPLLLQLTSRLQGVGALGQA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ITLIFNPTRKLPEQDIAQGSYIALPLTLLVLLAGYNHDKLIPLLLQLTSRLQGVGALGQA
             1150      1160      1170      1180      1190      1200

             1210      1220  
pF1KB1 ASDNSGPEDAKRQAKKQKTRRT
       ::::::::::::::::::::::
NP_001 ASDNSGPEDAKRQAKKQKTRRT
             1210      1220  

>>XP_005255375 (OMIM: 609159) PREDICTED: nodal modulator  (1267 aa)
 initn: 7996 init1: 7996 opt: 7996  Z-score: 9114.5  bits: 1698.6 E(85289):    0
Smith-Waterman score: 7996; 99.7% identity (99.8% similar) in 1222 aa overlap (1-1222:1-1222)

               10        20        30        40        50        60
pF1KB1 MLVGQGAGLLGPAVVTAAVVLLLSGVGPAHGSEDIVVGCGGFVKSDVEINYSLIEIKLYT
       :::::::: :::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MLVGQGAGPLGPAVVTAAVVLLLSGVGPAHGSEDIVVGCGGFVKSDVEINYSLIEIKLYT
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB1 KHGTLKYQTDCAPNNGYFMIPLYDKGDFILKIEPPLGWSFEPTTVELHVDGVSDICTKGG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 KHGTLKYQTDCAPNNGYFMIPLYDKGDFILKIEPPLGWSFEPTTVELHVDGVSDICTKGG
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB1 DINFVFTGFSVNGKVLSKGQPLGPAGVQVSLRNTGTEAKIQSTVTQPGGKFAFFKVLPGD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 DINFVFTGFSVNGKVLSKGQPLGPAGVQVSLRNTGTEAKIQSTVTQPGGKFAFFKVLPGD
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB1 YEILATHPTWALKEASTTVRVTNSNANAASPLIVAGYNVSGSVRSDGEPMKGVKFLLFSS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 YEILATHPTWALKEASTTVRVTNSNANAASPLIVAGYNVSGSVRSDGEPMKGVKFLLFSS
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB1 LVTKEDVLGCNVSPVPGFQPQDESLVYLCYTVSREDGSFSFYSLPSGGYTVIPFYRGERI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LVTKEDVLGCNVSPVPGFQPQDESLVYLCYTVSREDGSFSFYSLPSGGYTVIPFYRGERI
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KB1 TFDVAPSRLDFTVEHDSLKIEPVFHVMGFSVTGRVLNGPEGDGVPEAVVTLNNQIKVKTK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 TFDVAPSRLDFTVEHDSLKIEPVFHVMGFSVTGRVLNGPEGDGVPEAVVTLNNQIKVKTK
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KB1 ADGSFRLENITTGTYTIHAQKEHLYFETVTIKIAPNTPQLADIVATGFSVCGRISIIRFP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::.:::::::
XP_005 ADGSFRLENITTGTYTIHAQKEHLYFETVTIKIAPNTPQLADIVATGFSVCGQISIIRFP
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KB1 DTVKQMNKYKVVLSSQDKDKSLVTVETDAHGSFCFKAKPGTYKVQVMVPEAETRAGLTLK
       :::::::::::::::::::::::::::::::::::::.::::::::::::::::::::::
XP_005 DTVKQMNKYKVVLSSQDKDKSLVTVETDAHGSFCFKANPGTYKVQVMVPEAETRAGLTLK
              430       440       450       460       470       480

              490       500       510       520       530       540
pF1KB1 PQTFPLTVTDRPVMDVAFVQFLASVSGKVSCLDTCGDLLVTLQSLSRQGEKRSLQLSGKV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 PQTFPLTVTDRPVMDVAFVQFLASVSGKVSCLDTCGDLLVTLQSLSRQGEKRSLQLSGKV
              490       500       510       520       530       540

              550       560       570       580       590       600
pF1KB1 NAMTFTFDNVLPGKYKISIMHEDWCWKNKSLEVEVLEDDVSAVEFRQTGYMLRCSLSHAI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 NAMTFTFDNVLPGKYKISIMHEDWCWKNKSLEVEVLEDDVSAVEFRQTGYMLRCSLSHAI
              550       560       570       580       590       600

              610       620       630       640       650       660
pF1KB1 TLEFYQDGNGRENVGIYNLSKGVNRFCLSKPGVYKVTPRSCHRFEQAFYTYDTSSPSILT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 TLEFYQDGNGRENVGIYNLSKGVNRFCLSKPGVYKVTPRSCHRFEQAFYTYDTSSPSILT
              610       620       630       640       650       660

              670       680       690       700       710       720
pF1KB1 LTAIRHHVLGTITTDKMMDVTVTIKSSIDSEPALVLGPLKSVQELRREQQLAEIEARRQE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LTAIRHHVLGTITTDKMMDVTVTIKSSIDSEPALVLGPLKSVQELRREQQLAEIEARRQE
              670       680       690       700       710       720

              730       740       750       760       770       780
pF1KB1 REKNGNEEGEERMTKPSVQEMVDELQGPFSYDFSYWARSGEKITVTPSSKELLFYPPSME
       :::::::::::::::: :::::::::::::::::::::::::::::::::::::::::::
XP_005 REKNGNEEGEERMTKPPVQEMVDELQGPFSYDFSYWARSGEKITVTPSSKELLFYPPSME
              730       740       750       760       770       780

              790       800       810       820       830       840
pF1KB1 AVVSGESCPGKLIEIHGKAGLFLEGQIHPELEGVEIVISEKGASSPLITVFTDDKGAYSV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 AVVSGESCPGKLIEIHGKAGLFLEGQIHPELEGVEIVISEKGASSPLITVFTDDKGAYSV
              790       800       810       820       830       840

              850       860       870       880       890       900
pF1KB1 GPLHSDLEYTVTSQKEGYVLTAVEGTIGDFKAYALAGVSFEIKAEDDQPLPGVLLSLSGG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 GPLHSDLEYTVTSQKEGYVLTAVEGTIGDFKAYALAGVSFEIKAEDDQPLPGVLLSLSGG
              850       860       870       880       890       900

              910       920       930       940       950       960
pF1KB1 LFRSNLLTQDNGILTFSNLSPGQYYFKPMMKEFRFEPSSQMIEVQEGQNLKITITGYRTA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LFRSNLLTQDNGILTFSNLSPGQYYFKPMMKEFRFEPSSQMIEVQEGQNLKITITGYRTA
              910       920       930       940       950       960

              970       980       990      1000      1010      1020
pF1KB1 YSCYGTVSSLNGEPEQGVAMEAVGQNDCSIYGEDTVTDEEGKFRLRGLLPGCVYHVQLKA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 YSCYGTVSSLNGEPEQGVAMEAVGQNDCSIYGEDTVTDEEGKFRLRGLLPGCVYHVQLKA
              970       980       990      1000      1010      1020

             1030      1040      1050      1060      1070      1080
pF1KB1 EGNDHIERALPHHRVIEVGNNDIDDVNIIVFRQINQFDLSGNVITSSEYLPTLWVKLYKS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 EGNDHIERALPHHRVIEVGNNDIDDVNIIVFRQINQFDLSGNVITSSEYLPTLWVKLYKS
             1030      1040      1050      1060      1070      1080

             1090      1100      1110      1120      1130      1140
pF1KB1 ENLDNPIQTVSLGQSLFFHFPPLLRDGENYVVLLDSTLPRSQYDYILPQVSFTAVGYHKH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 ENLDNPIQTVSLGQSLFFHFPPLLRDGENYVVLLDSTLPRSQYDYILPQVSFTAVGYHKH
             1090      1100      1110      1120      1130      1140

             1150      1160      1170      1180      1190      1200
pF1KB1 ITLIFNPTRKLPEQDIAQGSYIALPLTLLVLLAGYNHDKLIPLLLQLTSRLQGVGALGQA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 ITLIFNPTRKLPEQDIAQGSYIALPLTLLVLLAGYNHDKLIPLLLQLTSRLQGVGALGQA
             1150      1160      1170      1180      1190      1200

             1210      1220                                        
pF1KB1 ASDNSGPEDAKRQAKKQKTRRT                                      
       ::::::::::::::::::::::                                      
XP_005 ASDNSGPEDAKRQAKKQKTRRTLRLQEEFQLMWCLVPWRGTLGIHLFSSLPFASEILLET
             1210      1220      1230      1240      1250      1260

>>NP_055102 (OMIM: 609157) nodal modulator 1 precursor [  (1222 aa)
 initn: 7976 init1: 7976 opt: 7976  Z-score: 9091.9  bits: 1694.4 E(85289):    0
Smith-Waterman score: 7976; 99.3% identity (99.8% similar) in 1222 aa overlap (1-1222:1-1222)

               10        20        30        40        50        60
pF1KB1 MLVGQGAGLLGPAVVTAAVVLLLSGVGPAHGSEDIVVGCGGFVKSDVEINYSLIEIKLYT
       :::::::: :::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 MLVGQGAGPLGPAVVTAAVVLLLSGVGPAHGSEDIVVGCGGFVKSDVEINYSLIEIKLYT
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB1 KHGTLKYQTDCAPNNGYFMIPLYDKGDFILKIEPPLGWSFEPTTVELHVDGVSDICTKGG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 KHGTLKYQTDCAPNNGYFMIPLYDKGDFILKIEPPLGWSFEPTTVELHVDGVSDICTKGG
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB1 DINFVFTGFSVNGKVLSKGQPLGPAGVQVSLRNTGTEAKIQSTVTQPGGKFAFFKVLPGD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 DINFVFTGFSVNGKVLSKGQPLGPAGVQVSLRNTGTEAKIQSTVTQPGGKFAFFKVLPGD
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB1 YEILATHPTWALKEASTTVRVTNSNANAASPLIVAGYNVSGSVRSDGEPMKGVKFLLFSS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 YEILATHPTWALKEASTTVRVTNSNANAASPLIVAGYNVSGSVRSDGEPMKGVKFLLFSS
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB1 LVTKEDVLGCNVSPVPGFQPQDESLVYLCYTVSREDGSFSFYSLPSGGYTVIPFYRGERI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 LVTKEDVLGCNVSPVPGFQPQDESLVYLCYTVSREDGSFSFYSLPSGGYTVIPFYRGERI
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KB1 TFDVAPSRLDFTVEHDSLKIEPVFHVMGFSVTGRVLNGPEGDGVPEAVVTLNNQIKVKTK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 TFDVAPSRLDFTVEHDSLKIEPVFHVMGFSVTGRVLNGPEGDGVPEAVVTLNNQIKVKTK
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KB1 ADGSFRLENITTGTYTIHAQKEHLYFETVTIKIAPNTPQLADIVATGFSVCGRISIIRFP
       :::::::::::::::::::::::::::::::::::::::::::.::::::::.:::::::
NP_055 ADGSFRLENITTGTYTIHAQKEHLYFETVTIKIAPNTPQLADIIATGFSVCGQISIIRFP
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KB1 DTVKQMNKYKVVLSSQDKDKSLVTVETDAHGSFCFKAKPGTYKVQVMVPEAETRAGLTLK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 DTVKQMNKYKVVLSSQDKDKSLVTVETDAHGSFCFKAKPGTYKVQVMVPEAETRAGLTLK
              430       440       450       460       470       480

              490       500       510       520       530       540
pF1KB1 PQTFPLTVTDRPVMDVAFVQFLASVSGKVSCLDTCGDLLVTLQSLSRQGEKRSLQLSGKV
       :::::::::.::.:::::::::::::::::::::::::::::::::::::::::::::::
NP_055 PQTFPLTVTNRPMMDVAFVQFLASVSGKVSCLDTCGDLLVTLQSLSRQGEKRSLQLSGKV
              490       500       510       520       530       540

              550       560       570       580       590       600
pF1KB1 NAMTFTFDNVLPGKYKISIMHEDWCWKNKSLEVEVLEDDVSAVEFRQTGYMLRCSLSHAI
       :::::::::::::::::::::::::::::::::::::::.::::::::::::::::::::
NP_055 NAMTFTFDNVLPGKYKISIMHEDWCWKNKSLEVEVLEDDMSAVEFRQTGYMLRCSLSHAI
              550       560       570       580       590       600

              610       620       630       640       650       660
pF1KB1 TLEFYQDGNGRENVGIYNLSKGVNRFCLSKPGVYKVTPRSCHRFEQAFYTYDTSSPSILT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 TLEFYQDGNGRENVGIYNLSKGVNRFCLSKPGVYKVTPRSCHRFEQAFYTYDTSSPSILT
              610       620       630       640       650       660

              670       680       690       700       710       720
pF1KB1 LTAIRHHVLGTITTDKMMDVTVTIKSSIDSEPALVLGPLKSVQELRREQQLAEIEARRQE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 LTAIRHHVLGTITTDKMMDVTVTIKSSIDSEPALVLGPLKSVQELRREQQLAEIEARRQE
              670       680       690       700       710       720

              730       740       750       760       770       780
pF1KB1 REKNGNEEGEERMTKPSVQEMVDELQGPFSYDFSYWARSGEKITVTPSSKELLFYPPSME
       :::::::::::::::: :::::::::::::::::::::::::::::::::::::::::::
NP_055 REKNGNEEGEERMTKPPVQEMVDELQGPFSYDFSYWARSGEKITVTPSSKELLFYPPSME
              730       740       750       760       770       780

              790       800       810       820       830       840
pF1KB1 AVVSGESCPGKLIEIHGKAGLFLEGQIHPELEGVEIVISEKGASSPLITVFTDDKGAYSV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 AVVSGESCPGKLIEIHGKAGLFLEGQIHPELEGVEIVISEKGASSPLITVFTDDKGAYSV
              790       800       810       820       830       840

              850       860       870       880       890       900
pF1KB1 GPLHSDLEYTVTSQKEGYVLTAVEGTIGDFKAYALAGVSFEIKAEDDQPLPGVLLSLSGG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 GPLHSDLEYTVTSQKEGYVLTAVEGTIGDFKAYALAGVSFEIKAEDDQPLPGVLLSLSGG
              850       860       870       880       890       900

              910       920       930       940       950       960
pF1KB1 LFRSNLLTQDNGILTFSNLSPGQYYFKPMMKEFRFEPSSQMIEVQEGQNLKITITGYRTA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 LFRSNLLTQDNGILTFSNLSPGQYYFKPMMKEFRFEPSSQMIEVQEGQNLKITITGYRTA
              910       920       930       940       950       960

              970       980       990      1000      1010      1020
pF1KB1 YSCYGTVSSLNGEPEQGVAMEAVGQNDCSIYGEDTVTDEEGKFRLRGLLPGCVYHVQLKA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 YSCYGTVSSLNGEPEQGVAMEAVGQNDCSIYGEDTVTDEEGKFRLRGLLPGCVYHVQLKA
              970       980       990      1000      1010      1020

             1030      1040      1050      1060      1070      1080
pF1KB1 EGNDHIERALPHHRVIEVGNNDIDDVNIIVFRQINQFDLSGNVITSSEYLPTLWVKLYKS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 EGNDHIERALPHHRVIEVGNNDIDDVNIIVFRQINQFDLSGNVITSSEYLPTLWVKLYKS
             1030      1040      1050      1060      1070      1080

             1090      1100      1110      1120      1130      1140
pF1KB1 ENLDNPIQTVSLGQSLFFHFPPLLRDGENYVVLLDSTLPRSQYDYILPQVSFTAVGYHKH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 ENLDNPIQTVSLGQSLFFHFPPLLRDGENYVVLLDSTLPRSQYDYILPQVSFTAVGYHKH
             1090      1100      1110      1120      1130      1140

             1150      1160      1170      1180      1190      1200
pF1KB1 ITLIFNPTRKLPEQDIAQGSYIALPLTLLVLLAGYNHDKLIPLLLQLTSRLQGVGALGQA
       :::::::::::::::::::::::::::::::::::::::::::::::::::::: :::::
NP_055 ITLIFNPTRKLPEQDIAQGSYIALPLTLLVLLAGYNHDKLIPLLLQLTSRLQGVRALGQA
             1150      1160      1170      1180      1190      1200

             1210      1220  
pF1KB1 ASDNSGPEDAKRQAKKQKTRRT
       ::::::::::::::::::::::
NP_055 ASDNSGPEDAKRQAKKQKTRRT
             1210      1220  

>>XP_016855194 (OMIM: 609159) PREDICTED: nodal modulator  (811 aa)
 initn: 5152 init1: 5152 opt: 5152  Z-score: 5872.9  bits: 1098.2 E(85289):    0
Smith-Waterman score: 5152; 99.5% identity (99.6% similar) in 788 aa overlap (1-788:1-788)

               10        20        30        40        50        60
pF1KB1 MLVGQGAGLLGPAVVTAAVVLLLSGVGPAHGSEDIVVGCGGFVKSDVEINYSLIEIKLYT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MLVGQGAGLLGPAVVTAAVVLLLSGVGPAHGSEDIVVGCGGFVKSDVEINYSLIEIKLYT
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB1 KHGTLKYQTDCAPNNGYFMIPLYDKGDFILKIEPPLGWSFEPTTVELHVDGVSDICTKGG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KHGTLKYQTDCAPNNGYFMIPLYDKGDFILKIEPPLGWSFEPTTVELHVDGVSDICTKGG
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB1 DINFVFTGFSVNGKVLSKGQPLGPAGVQVSLRNTGTEAKIQSTVTQPGGKFAFFKVLPGD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DINFVFTGFSVNGKVLSKGQPLGPAGVQVSLRNTGTEAKIQSTVTQPGGKFAFFKVLPGD
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB1 YEILATHPTWALKEASTTVRVTNSNANAASPLIVAGYNVSGSVRSDGEPMKGVKFLLFSS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 YEILATHPTWALKEASTTVRVTNSNANAASPLIVAGYNVSGSVRSDGEPMKGVKFLLFSS
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB1 LVTKEDVLGCNVSPVPGFQPQDESLVYLCYTVSREDGSFSFYSLPSGGYTVIPFYRGERI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LVTKEDVLGCNVSPVPGFQPQDESLVYLCYTVSREDGSFSFYSLPSGGYTVIPFYRGERI
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KB1 TFDVAPSRLDFTVEHDSLKIEPVFHVMGFSVTGRVLNGPEGDGVPEAVVTLNNQIKVKTK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TFDVAPSRLDFTVEHDSLKIEPVFHVMGFSVTGRVLNGPEGDGVPEAVVTLNNQIKVKTK
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KB1 ADGSFRLENITTGTYTIHAQKEHLYFETVTIKIAPNTPQLADIVATGFSVCGRISIIRFP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ADGSFRLENITTGTYTIHAQKEHLYFETVTIKIAPNTPQLADIVATGFSVCGRISIIRFP
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KB1 DTVKQMNKYKVVLSSQDKDKSLVTVETDAHGSFCFKAKPGTYKVQVMVPEAETRAGLTLK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DTVKQMNKYKVVLSSQDKDKSLVTVETDAHGSFCFKAKPGTYKVQVMVPEAETRAGLTLK
              430       440       450       460       470       480

              490       500       510       520       530       540
pF1KB1 PQTFPLTVTDRPVMDVAFVQFLASVSGKVSCLDTCGDLLVTLQSLSRQGEKRSLQLSGKV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PQTFPLTVTDRPVMDVAFVQFLASVSGKVSCLDTCGDLLVTLQSLSRQGEKRSLQLSGKV
              490       500       510       520       530       540

              550       560       570       580       590       600
pF1KB1 NAMTFTFDNVLPGKYKISIMHEDWCWKNKSLEVEVLEDDVSAVEFRQTGYMLRCSLSHAI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NAMTFTFDNVLPGKYKISIMHEDWCWKNKSLEVEVLEDDVSAVEFRQTGYMLRCSLSHAI
              550       560       570       580       590       600

              610       620       630       640       650       660
pF1KB1 TLEFYQDGNGRENVGIYNLSKGVNRFCLSKPGVYKVTPRSCHRFEQAFYTYDTSSPSILT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TLEFYQDGNGRENVGIYNLSKGVNRFCLSKPGVYKVTPRSCHRFEQAFYTYDTSSPSILT
              610       620       630       640       650       660

              670       680       690       700       710       720
pF1KB1 LTAIRHHVLGTITTDKMMDVTVTIKSSIDSEPALVLGPLKSVQELRREQQLAEIEARRQE
       ::::::::: ::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LTAIRHHVLCTITTDKMMDVTVTIKSSIDSEPALVLGPLKSVQELRREQQLAEIEARRQE
              670       680       690       700       710       720

              730       740       750       760       770       780
pF1KB1 REKNGNEEGEERMTKPSVQEMVDELQGPFSYDFSYWARSGEKITVTPSSKELLFYPPSME
       :::::::::::::::: :::::::::::::::::::::::::::::::::::::::::::
XP_016 REKNGNEEGEERMTKPPVQEMVDELQGPFSYDFSYWARSGEKITVTPSSKELLFYPPSME
              730       740       750       760       770       780

              790       800       810       820       830       840
pF1KB1 AVVSGESCPGKLIEIHGKAGLFLEGQIHPELEGVEIVISEKGASSPLITVFTDDKGAYSV
       ::::: .:                                                    
XP_016 AVVSGGKCQLSERMSHTPLQLFPCLHLQVDL                             
              790       800       810                              

>>XP_016878645 (OMIM: 609158) PREDICTED: nodal modulator  (651 aa)
 initn: 3998 init1: 3960 opt: 3960  Z-score: 4514.5  bits: 846.5 E(85289):    0
Smith-Waterman score: 3960; 100.0% identity (100.0% similar) in 602 aa overlap (1-602:1-602)

               10        20        30        40        50        60
pF1KB1 MLVGQGAGLLGPAVVTAAVVLLLSGVGPAHGSEDIVVGCGGFVKSDVEINYSLIEIKLYT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MLVGQGAGLLGPAVVTAAVVLLLSGVGPAHGSEDIVVGCGGFVKSDVEINYSLIEIKLYT
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB1 KHGTLKYQTDCAPNNGYFMIPLYDKGDFILKIEPPLGWSFEPTTVELHVDGVSDICTKGG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KHGTLKYQTDCAPNNGYFMIPLYDKGDFILKIEPPLGWSFEPTTVELHVDGVSDICTKGG
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB1 DINFVFTGFSVNGKVLSKGQPLGPAGVQVSLRNTGTEAKIQSTVTQPGGKFAFFKVLPGD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DINFVFTGFSVNGKVLSKGQPLGPAGVQVSLRNTGTEAKIQSTVTQPGGKFAFFKVLPGD
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB1 YEILATHPTWALKEASTTVRVTNSNANAASPLIVAGYNVSGSVRSDGEPMKGVKFLLFSS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 YEILATHPTWALKEASTTVRVTNSNANAASPLIVAGYNVSGSVRSDGEPMKGVKFLLFSS
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB1 LVTKEDVLGCNVSPVPGFQPQDESLVYLCYTVSREDGSFSFYSLPSGGYTVIPFYRGERI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LVTKEDVLGCNVSPVPGFQPQDESLVYLCYTVSREDGSFSFYSLPSGGYTVIPFYRGERI
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KB1 TFDVAPSRLDFTVEHDSLKIEPVFHVMGFSVTGRVLNGPEGDGVPEAVVTLNNQIKVKTK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TFDVAPSRLDFTVEHDSLKIEPVFHVMGFSVTGRVLNGPEGDGVPEAVVTLNNQIKVKTK
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KB1 ADGSFRLENITTGTYTIHAQKEHLYFETVTIKIAPNTPQLADIVATGFSVCGRISIIRFP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ADGSFRLENITTGTYTIHAQKEHLYFETVTIKIAPNTPQLADIVATGFSVCGRISIIRFP
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KB1 DTVKQMNKYKVVLSSQDKDKSLVTVETDAHGSFCFKAKPGTYKVQVMVPEAETRAGLTLK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DTVKQMNKYKVVLSSQDKDKSLVTVETDAHGSFCFKAKPGTYKVQVMVPEAETRAGLTLK
              430       440       450       460       470       480

              490       500       510       520       530       540
pF1KB1 PQTFPLTVTDRPVMDVAFVQFLASVSGKVSCLDTCGDLLVTLQSLSRQGEKRSLQLSGKV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PQTFPLTVTDRPVMDVAFVQFLASVSGKVSCLDTCGDLLVTLQSLSRQGEKRSLQLSGKV
              490       500       510       520       530       540

              550       560       570       580       590       600
pF1KB1 NAMTFTFDNVLPGKYKISIMHEDWCWKNKSLEVEVLEDDVSAVEFRQTGYMLRCSLSHAI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NAMTFTFDNVLPGKYKISIMHEDWCWKNKSLEVEVLEDDVSAVEFRQTGYMLRCSLSHAI
              550       560       570       580       590       600

              610       620       630       640       650       660
pF1KB1 TLEFYQDGNGRENVGIYNLSKGVNRFCLSKPGVYKVTPRSCHRFEQAFYTYDTSSPSILT
       ::                                                          
XP_016 TLAQPYCSGEMCPGTSELKTPRWGLFFSCFPVYFHSFVTDQLRSLIYLLMR         
              610       620       630       640       650          




1222 residues in 1 query   sequences
60827320 residues in 85289 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Fri Nov  4 02:04:01 2016 done: Fri Nov  4 02:04:03 2016
 Total Scan time: 13.060 Total Display time:  0.350

Function used was FASTA [36.3.4 Apr, 2011]
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