Result of FASTA (omim) for pF1KA1534
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KA1534, 811 aa
  1>>>pF1KA1534 811 - 811 aa - 811 aa
Library: /omim/omim.rfq.tfa
  60827320 residues in 85289 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 7.8455+/-0.000315; mu= 9.7183+/- 0.020
 mean_var=145.2781+/-29.087, 0's: 0 Z-trim(120.5): 146  B-trim: 0 in 0/55
 Lambda= 0.106408
 statistics sampled from 35590 (35741) to 35590 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.749), E-opt: 0.2 (0.419), width:  16
 Scan time: 14.950

The best scores are:                                      opt bits E(85289)
NP_001137535 (OMIM: 606733) oxysterol-binding prot ( 811) 5485 853.9       0
NP_663613 (OMIM: 606733) oxysterol-binding protein ( 811) 5485 853.9       0
XP_016872652 (OMIM: 606733) PREDICTED: oxysterol-b ( 879) 4599 717.9 4.8e-206
XP_011518175 (OMIM: 606733) PREDICTED: oxysterol-b ( 879) 4599 717.9 4.8e-206
NP_065947 (OMIM: 606733) oxysterol-binding protein ( 879) 4599 717.9 4.8e-206
XP_016872653 (OMIM: 606733) PREDICTED: oxysterol-b ( 509) 3476 545.4 2.4e-154
NP_001003712 (OMIM: 606736) oxysterol-binding prot ( 847) 2055 327.3 1.7e-88
NP_001306581 (OMIM: 606736) oxysterol-binding prot ( 847) 2055 327.3 1.7e-88
XP_006719287 (OMIM: 606736) PREDICTED: oxysterol-b ( 847) 2055 327.3 1.7e-88
NP_001306584 (OMIM: 606736) oxysterol-binding prot ( 864) 2055 327.3 1.7e-88
NP_001306582 (OMIM: 606736) oxysterol-binding prot ( 886) 2055 327.3 1.8e-88
XP_016874258 (OMIM: 606736) PREDICTED: oxysterol-b ( 886) 2055 327.3 1.8e-88
NP_065892 (OMIM: 606736) oxysterol-binding protein ( 889) 2055 327.3 1.8e-88
XP_005268678 (OMIM: 606736) PREDICTED: oxysterol-b ( 889) 2055 327.3 1.8e-88
XP_011536157 (OMIM: 606736) PREDICTED: oxysterol-b ( 899) 2055 327.4 1.8e-88
XP_011536159 (OMIM: 606736) PREDICTED: oxysterol-b ( 902) 2055 327.4 1.8e-88
XP_011536158 (OMIM: 606736) PREDICTED: oxysterol-b ( 902) 2055 327.4 1.8e-88
XP_016874257 (OMIM: 606736) PREDICTED: oxysterol-b ( 912) 2055 327.4 1.8e-88
XP_016861158 (OMIM: 606738) PREDICTED: oxysterol-b ( 596)  541 94.8 1.2e-18
XP_011531628 (OMIM: 606738) PREDICTED: oxysterol-b ( 632)  541 94.8 1.2e-18
XP_016861156 (OMIM: 606738) PREDICTED: oxysterol-b ( 632)  541 94.8 1.2e-18
XP_016861157 (OMIM: 606738) PREDICTED: oxysterol-b ( 632)  541 94.8 1.2e-18
NP_060254 (OMIM: 606738) oxysterol-binding protein ( 764)  541 94.9 1.4e-18
XP_005264900 (OMIM: 606738) PREDICTED: oxysterol-b ( 769)  541 94.9 1.4e-18
XP_016861159 (OMIM: 606738) PREDICTED: oxysterol-b ( 551)  528 92.8 4.4e-18
NP_001167531 (OMIM: 606738) oxysterol-binding prot ( 700)  528 92.9 5.3e-18
XP_005264901 (OMIM: 606738) PREDICTED: oxysterol-b ( 705)  528 92.9 5.4e-18
XP_005264902 (OMIM: 606738) PREDICTED: oxysterol-b ( 428)  510 90.0 2.4e-17
NP_073613 (OMIM: 606739) oxysterol-binding protein ( 747)  511 90.3 3.4e-17
XP_016881022 (OMIM: 606730) PREDICTED: oxysterol-b ( 437)  434 78.3 7.9e-14
NP_060500 (OMIM: 606730) oxysterol-binding protein ( 437)  434 78.3 7.9e-14
XP_016881023 (OMIM: 606730) PREDICTED: oxysterol-b ( 437)  434 78.3 7.9e-14
NP_001229437 (OMIM: 606730) oxysterol-binding prot ( 568)  434 78.4 9.9e-14
XP_006722443 (OMIM: 606730) PREDICTED: oxysterol-b ( 925)  434 78.5 1.5e-13
NP_542164 (OMIM: 606730) oxysterol-binding protein ( 950)  434 78.5 1.5e-13
XP_016881019 (OMIM: 606730) PREDICTED: oxysterol-b ( 968)  434 78.5 1.5e-13
XP_016883657 (OMIM: 606731,616340) PREDICTED: oxys ( 370)  424 76.8   2e-13
NP_653081 (OMIM: 606731,616340) oxysterol-binding  ( 480)  424 76.8 2.5e-13
XP_016883654 (OMIM: 606731,616340) PREDICTED: oxys ( 480)  424 76.8 2.5e-13
XP_016883653 (OMIM: 606731,616340) PREDICTED: oxys ( 516)  424 76.8 2.6e-13
XP_016883652 (OMIM: 606731,616340) PREDICTED: oxys ( 516)  424 76.8 2.6e-13
NP_055650 (OMIM: 606731,616340) oxysterol-binding  ( 468)  421 76.4 3.4e-13
XP_016858762 (OMIM: 606734) PREDICTED: oxysterol-b ( 872)  416 75.7 9.6e-13
NP_001188410 (OMIM: 606734) oxysterol-binding prot ( 903)  416 75.7 9.9e-13
XP_016858759 (OMIM: 606734) PREDICTED: oxysterol-b ( 903)  416 75.7 9.9e-13
XP_011508841 (OMIM: 606734) PREDICTED: oxysterol-b ( 928)  416 75.7   1e-12
NP_115912 (OMIM: 606734) oxysterol-binding protein ( 934)  416 75.8   1e-12
NP_665682 (OMIM: 606734) oxysterol-binding protein ( 938)  416 75.8   1e-12
NP_001188409 (OMIM: 606734) oxysterol-binding prot ( 959)  416 75.8   1e-12
XP_016858756 (OMIM: 606734) PREDICTED: oxysterol-b ( 959)  416 75.8   1e-12


>>NP_001137535 (OMIM: 606733) oxysterol-binding protein-  (811 aa)
 initn: 5485 init1: 5485 opt: 5485  Z-score: 4555.8  bits: 853.9 E(85289):    0
Smith-Waterman score: 5485; 100.0% identity (100.0% similar) in 811 aa overlap (1-811:1-811)

               10        20        30        40        50        60
pF1KA1 MKEEAFLRRRFSLCPPSSTPQKVDPRKLTRNLLLSGDNELYPLSPGKDMEPNGPSLPRDE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MKEEAFLRRRFSLCPPSSTPQKVDPRKLTRNLLLSGDNELYPLSPGKDMEPNGPSLPRDE
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KA1 GPPTPSSATKVPPAEYRLCNGSDKECVSPTARVTKKETLKAQKENYRQEKKRATRQLLSA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GPPTPSSATKVPPAEYRLCNGSDKECVSPTARVTKKETLKAQKENYRQEKKRATRQLLSA
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KA1 LTDPSVVIMADSLKGPKGESVGSITQPLPSSYLIFRAASESDGRCWLDALELALRCSSLL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LTDPSVVIMADSLKGPKGESVGSITQPLPSSYLIFRAASESDGRCWLDALELALRCSSLL
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KA1 RLGTCKPGRDGEPGTSPDASPSSLCGLPASATVHPDQDLFPLNGSSLENDAFSDKSEREN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RLGTCKPGRDGEPGTSPDASPSSLCGLPASATVHPDQDLFPLNGSSLENDAFSDKSEREN
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KA1 PEESDTETQDHSRKTESGSDQSETPGAPVRRGTTYVEQVQEELGELGEASQVETVSEENK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PEESDTETQDHSRKTESGSDQSETPGAPVRRGTTYVEQVQEELGELGEASQVETVSEENK
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KA1 SLMWTLLKQLRPGMDLSRVVLPTFVLEPRSFLNKLSDYYYHADLLSRAAVEEDAYSRMKL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SLMWTLLKQLRPGMDLSRVVLPTFVLEPRSFLNKLSDYYYHADLLSRAAVEEDAYSRMKL
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KA1 VLRWYLSGFYKKPKGIKKPYNPILGETFRCCWFHPQTDSRTFYIAEQVSHHPPVSAFHVS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VLRWYLSGFYKKPKGIKKPYNPILGETFRCCWFHPQTDSRTFYIAEQVSHHPPVSAFHVS
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KA1 NRKDGFCISGSITAKSRFYGNSLSALLDGKATLTFLNRAEDYTLTMPYAHCKGILYGTMT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NRKDGFCISGSITAKSRFYGNSLSALLDGKATLTFLNRAEDYTLTMPYAHCKGILYGTMT
              430       440       450       460       470       480

              490       500       510       520       530       540
pF1KA1 LELGGKVTIECAKNNFQAQLEFKLKPFFGGSTSINQISGKITSGEEVLASLSGHWDRDVF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LELGGKVTIECAKNNFQAQLEFKLKPFFGGSTSINQISGKITSGEEVLASLSGHWDRDVF
              490       500       510       520       530       540

              550       560       570       580       590       600
pF1KA1 IKEEGSGSSALFWTPSGEVRRQRLRQHTVPLEEQTELESERLWQHVTRAISKGDQHRATQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IKEEGSGSSALFWTPSGEVRRQRLRQHTVPLEEQTELESERLWQHVTRAISKGDQHRATQ
              550       560       570       580       590       600

              610       620       630       640       650       660
pF1KA1 EKFALEEAQRQRARERQESLMPWKPQLFHLDPITQEWHYRYEDHSPWDPLKDIAQFEQDG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EKFALEEAQRQRARERQESLMPWKPQLFHLDPITQEWHYRYEDHSPWDPLKDIAQFEQDG
              610       620       630       640       650       660

              670       680       690       700       710       720
pF1KA1 ILRTLQQEAVARQTTFLGSPGPRHERSGPDQRLRKASDQPSGHSQATESSGSTPESCPEL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ILRTLQQEAVARQTTFLGSPGPRHERSGPDQRLRKASDQPSGHSQATESSGSTPESCPEL
              670       680       690       700       710       720

              730       740       750       760       770       780
pF1KA1 SDEEQDGDFVPGGESPCPRCRKEARRLQALHEAILSIREAQQELHRHLSAMLSSTARAAQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SDEEQDGDFVPGGESPCPRCRKEARRLQALHEAILSIREAQQELHRHLSAMLSSTARAAQ
              730       740       750       760       770       780

              790       800       810 
pF1KA1 APTPGLLQSPRSWFLLCVFLACQLFINHILK
       :::::::::::::::::::::::::::::::
NP_001 APTPGLLQSPRSWFLLCVFLACQLFINHILK
              790       800       810 

>>NP_663613 (OMIM: 606733) oxysterol-binding protein-rel  (811 aa)
 initn: 5485 init1: 5485 opt: 5485  Z-score: 4555.8  bits: 853.9 E(85289):    0
Smith-Waterman score: 5485; 100.0% identity (100.0% similar) in 811 aa overlap (1-811:1-811)

               10        20        30        40        50        60
pF1KA1 MKEEAFLRRRFSLCPPSSTPQKVDPRKLTRNLLLSGDNELYPLSPGKDMEPNGPSLPRDE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_663 MKEEAFLRRRFSLCPPSSTPQKVDPRKLTRNLLLSGDNELYPLSPGKDMEPNGPSLPRDE
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KA1 GPPTPSSATKVPPAEYRLCNGSDKECVSPTARVTKKETLKAQKENYRQEKKRATRQLLSA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_663 GPPTPSSATKVPPAEYRLCNGSDKECVSPTARVTKKETLKAQKENYRQEKKRATRQLLSA
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KA1 LTDPSVVIMADSLKGPKGESVGSITQPLPSSYLIFRAASESDGRCWLDALELALRCSSLL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_663 LTDPSVVIMADSLKGPKGESVGSITQPLPSSYLIFRAASESDGRCWLDALELALRCSSLL
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KA1 RLGTCKPGRDGEPGTSPDASPSSLCGLPASATVHPDQDLFPLNGSSLENDAFSDKSEREN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_663 RLGTCKPGRDGEPGTSPDASPSSLCGLPASATVHPDQDLFPLNGSSLENDAFSDKSEREN
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KA1 PEESDTETQDHSRKTESGSDQSETPGAPVRRGTTYVEQVQEELGELGEASQVETVSEENK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_663 PEESDTETQDHSRKTESGSDQSETPGAPVRRGTTYVEQVQEELGELGEASQVETVSEENK
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KA1 SLMWTLLKQLRPGMDLSRVVLPTFVLEPRSFLNKLSDYYYHADLLSRAAVEEDAYSRMKL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_663 SLMWTLLKQLRPGMDLSRVVLPTFVLEPRSFLNKLSDYYYHADLLSRAAVEEDAYSRMKL
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KA1 VLRWYLSGFYKKPKGIKKPYNPILGETFRCCWFHPQTDSRTFYIAEQVSHHPPVSAFHVS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_663 VLRWYLSGFYKKPKGIKKPYNPILGETFRCCWFHPQTDSRTFYIAEQVSHHPPVSAFHVS
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KA1 NRKDGFCISGSITAKSRFYGNSLSALLDGKATLTFLNRAEDYTLTMPYAHCKGILYGTMT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_663 NRKDGFCISGSITAKSRFYGNSLSALLDGKATLTFLNRAEDYTLTMPYAHCKGILYGTMT
              430       440       450       460       470       480

              490       500       510       520       530       540
pF1KA1 LELGGKVTIECAKNNFQAQLEFKLKPFFGGSTSINQISGKITSGEEVLASLSGHWDRDVF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_663 LELGGKVTIECAKNNFQAQLEFKLKPFFGGSTSINQISGKITSGEEVLASLSGHWDRDVF
              490       500       510       520       530       540

              550       560       570       580       590       600
pF1KA1 IKEEGSGSSALFWTPSGEVRRQRLRQHTVPLEEQTELESERLWQHVTRAISKGDQHRATQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_663 IKEEGSGSSALFWTPSGEVRRQRLRQHTVPLEEQTELESERLWQHVTRAISKGDQHRATQ
              550       560       570       580       590       600

              610       620       630       640       650       660
pF1KA1 EKFALEEAQRQRARERQESLMPWKPQLFHLDPITQEWHYRYEDHSPWDPLKDIAQFEQDG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_663 EKFALEEAQRQRARERQESLMPWKPQLFHLDPITQEWHYRYEDHSPWDPLKDIAQFEQDG
              610       620       630       640       650       660

              670       680       690       700       710       720
pF1KA1 ILRTLQQEAVARQTTFLGSPGPRHERSGPDQRLRKASDQPSGHSQATESSGSTPESCPEL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_663 ILRTLQQEAVARQTTFLGSPGPRHERSGPDQRLRKASDQPSGHSQATESSGSTPESCPEL
              670       680       690       700       710       720

              730       740       750       760       770       780
pF1KA1 SDEEQDGDFVPGGESPCPRCRKEARRLQALHEAILSIREAQQELHRHLSAMLSSTARAAQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_663 SDEEQDGDFVPGGESPCPRCRKEARRLQALHEAILSIREAQQELHRHLSAMLSSTARAAQ
              730       740       750       760       770       780

              790       800       810 
pF1KA1 APTPGLLQSPRSWFLLCVFLACQLFINHILK
       :::::::::::::::::::::::::::::::
NP_663 APTPGLLQSPRSWFLLCVFLACQLFINHILK
              790       800       810 

>>XP_016872652 (OMIM: 606733) PREDICTED: oxysterol-bindi  (879 aa)
 initn: 4599 init1: 4599 opt: 4599  Z-score: 3820.2  bits: 717.9 E(85289): 4.8e-206
Smith-Waterman score: 5098; 91.9% identity (91.9% similar) in 843 aa overlap (37-811:37-879)

         10        20        30        40        50        60      
pF1KA1 LRRRFSLCPPSSTPQKVDPRKLTRNLLLSGDNELYPLSPGKDMEPNGPSLPRDEGPPTPS
                                     ::::::::::::::::::::::::::::::
XP_016 LRRRFSLCPPSSTPQKVDPRKLTRNLLLSGDNELYPLSPGKDMEPNGPSLPRDEGPPTPS
         10        20        30        40        50        60      

         70        80        90       100       110       120      
pF1KA1 SATKVPPAEYRLCNGSDKECVSPTARVTKKETLKAQKENYRQEKKRATRQLLSALTDPSV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SATKVPPAEYRLCNGSDKECVSPTARVTKKETLKAQKENYRQEKKRATRQLLSALTDPSV
         70        80        90       100       110       120      

        130                                                        
pF1KA1 VIMADSLK----------------------------------------------------
       ::::::::                                                    
XP_016 VIMADSLKIRGTLKSWTKLWCVLKPGVLLIYKTPKVGQWVGTVLLHCCELIERPSKKDGF
        130       140       150       160       170       180      

                          140       150       160       170        
pF1KA1 ----------------GPKGESVGSITQPLPSSYLIFRAASESDGRCWLDALELALRCSS
                       ::::::::::::::::::::::::::::::::::::::::::::
XP_016 CFKLFHPLDQSVWAVKGPKGESVGSITQPLPSSYLIFRAASESDGRCWLDALELALRCSS
        190       200       210       220       230       240      

      180       190       200       210       220       230        
pF1KA1 LLRLGTCKPGRDGEPGTSPDASPSSLCGLPASATVHPDQDLFPLNGSSLENDAFSDKSER
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LLRLGTCKPGRDGEPGTSPDASPSSLCGLPASATVHPDQDLFPLNGSSLENDAFSDKSER
        250       260       270       280       290       300      

      240       250       260       270       280       290        
pF1KA1 ENPEESDTETQDHSRKTESGSDQSETPGAPVRRGTTYVEQVQEELGELGEASQVETVSEE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ENPEESDTETQDHSRKTESGSDQSETPGAPVRRGTTYVEQVQEELGELGEASQVETVSEE
        310       320       330       340       350       360      

      300       310       320       330       340       350        
pF1KA1 NKSLMWTLLKQLRPGMDLSRVVLPTFVLEPRSFLNKLSDYYYHADLLSRAAVEEDAYSRM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NKSLMWTLLKQLRPGMDLSRVVLPTFVLEPRSFLNKLSDYYYHADLLSRAAVEEDAYSRM
        370       380       390       400       410       420      

      360       370       380       390       400       410        
pF1KA1 KLVLRWYLSGFYKKPKGIKKPYNPILGETFRCCWFHPQTDSRTFYIAEQVSHHPPVSAFH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KLVLRWYLSGFYKKPKGIKKPYNPILGETFRCCWFHPQTDSRTFYIAEQVSHHPPVSAFH
        430       440       450       460       470       480      

      420       430       440       450       460       470        
pF1KA1 VSNRKDGFCISGSITAKSRFYGNSLSALLDGKATLTFLNRAEDYTLTMPYAHCKGILYGT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VSNRKDGFCISGSITAKSRFYGNSLSALLDGKATLTFLNRAEDYTLTMPYAHCKGILYGT
        490       500       510       520       530       540      

      480       490       500       510       520       530        
pF1KA1 MTLELGGKVTIECAKNNFQAQLEFKLKPFFGGSTSINQISGKITSGEEVLASLSGHWDRD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MTLELGGKVTIECAKNNFQAQLEFKLKPFFGGSTSINQISGKITSGEEVLASLSGHWDRD
        550       560       570       580       590       600      

      540       550       560       570       580       590        
pF1KA1 VFIKEEGSGSSALFWTPSGEVRRQRLRQHTVPLEEQTELESERLWQHVTRAISKGDQHRA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VFIKEEGSGSSALFWTPSGEVRRQRLRQHTVPLEEQTELESERLWQHVTRAISKGDQHRA
        610       620       630       640       650       660      

      600       610       620       630       640       650        
pF1KA1 TQEKFALEEAQRQRARERQESLMPWKPQLFHLDPITQEWHYRYEDHSPWDPLKDIAQFEQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TQEKFALEEAQRQRARERQESLMPWKPQLFHLDPITQEWHYRYEDHSPWDPLKDIAQFEQ
        670       680       690       700       710       720      

      660       670       680       690       700       710        
pF1KA1 DGILRTLQQEAVARQTTFLGSPGPRHERSGPDQRLRKASDQPSGHSQATESSGSTPESCP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DGILRTLQQEAVARQTTFLGSPGPRHERSGPDQRLRKASDQPSGHSQATESSGSTPESCP
        730       740       750       760       770       780      

      720       730       740       750       760       770        
pF1KA1 ELSDEEQDGDFVPGGESPCPRCRKEARRLQALHEAILSIREAQQELHRHLSAMLSSTARA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ELSDEEQDGDFVPGGESPCPRCRKEARRLQALHEAILSIREAQQELHRHLSAMLSSTARA
        790       800       810       820       830       840      

      780       790       800       810 
pF1KA1 AQAPTPGLLQSPRSWFLLCVFLACQLFINHILK
       :::::::::::::::::::::::::::::::::
XP_016 AQAPTPGLLQSPRSWFLLCVFLACQLFINHILK
        850       860       870         

>--
 initn: 241 init1: 241 opt: 241  Z-score: 204.5  bits: 48.9 E(85289): 0.00012
Smith-Waterman score: 241; 100.0% identity (100.0% similar) in 36 aa overlap (1-36:1-36)

               10        20        30        40        50        60
pF1KA1 MKEEAFLRRRFSLCPPSSTPQKVDPRKLTRNLLLSGDNELYPLSPGKDMEPNGPSLPRDE
       ::::::::::::::::::::::::::::::::::::                        
XP_016 MKEEAFLRRRFSLCPPSSTPQKVDPRKLTRNLLLSGDNELYPLSPGKDMEPNGPSLPRDE
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KA1 GPPTPSSATKVPPAEYRLCNGSDKECVSPTARVTKKETLKAQKENYRQEKKRATRQLLSA
                                                                   
XP_016 GPPTPSSATKVPPAEYRLCNGSDKECVSPTARVTKKETLKAQKENYRQEKKRATRQLLSA
               70        80        90       100       110       120

>>XP_011518175 (OMIM: 606733) PREDICTED: oxysterol-bindi  (879 aa)
 initn: 4599 init1: 4599 opt: 4599  Z-score: 3820.2  bits: 717.9 E(85289): 4.8e-206
Smith-Waterman score: 5098; 91.9% identity (91.9% similar) in 843 aa overlap (37-811:37-879)

         10        20        30        40        50        60      
pF1KA1 LRRRFSLCPPSSTPQKVDPRKLTRNLLLSGDNELYPLSPGKDMEPNGPSLPRDEGPPTPS
                                     ::::::::::::::::::::::::::::::
XP_011 LRRRFSLCPPSSTPQKVDPRKLTRNLLLSGDNELYPLSPGKDMEPNGPSLPRDEGPPTPS
         10        20        30        40        50        60      

         70        80        90       100       110       120      
pF1KA1 SATKVPPAEYRLCNGSDKECVSPTARVTKKETLKAQKENYRQEKKRATRQLLSALTDPSV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SATKVPPAEYRLCNGSDKECVSPTARVTKKETLKAQKENYRQEKKRATRQLLSALTDPSV
         70        80        90       100       110       120      

        130                                                        
pF1KA1 VIMADSLK----------------------------------------------------
       ::::::::                                                    
XP_011 VIMADSLKIRGTLKSWTKLWCVLKPGVLLIYKTPKVGQWVGTVLLHCCELIERPSKKDGF
        130       140       150       160       170       180      

                          140       150       160       170        
pF1KA1 ----------------GPKGESVGSITQPLPSSYLIFRAASESDGRCWLDALELALRCSS
                       ::::::::::::::::::::::::::::::::::::::::::::
XP_011 CFKLFHPLDQSVWAVKGPKGESVGSITQPLPSSYLIFRAASESDGRCWLDALELALRCSS
        190       200       210       220       230       240      

      180       190       200       210       220       230        
pF1KA1 LLRLGTCKPGRDGEPGTSPDASPSSLCGLPASATVHPDQDLFPLNGSSLENDAFSDKSER
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LLRLGTCKPGRDGEPGTSPDASPSSLCGLPASATVHPDQDLFPLNGSSLENDAFSDKSER
        250       260       270       280       290       300      

      240       250       260       270       280       290        
pF1KA1 ENPEESDTETQDHSRKTESGSDQSETPGAPVRRGTTYVEQVQEELGELGEASQVETVSEE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ENPEESDTETQDHSRKTESGSDQSETPGAPVRRGTTYVEQVQEELGELGEASQVETVSEE
        310       320       330       340       350       360      

      300       310       320       330       340       350        
pF1KA1 NKSLMWTLLKQLRPGMDLSRVVLPTFVLEPRSFLNKLSDYYYHADLLSRAAVEEDAYSRM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NKSLMWTLLKQLRPGMDLSRVVLPTFVLEPRSFLNKLSDYYYHADLLSRAAVEEDAYSRM
        370       380       390       400       410       420      

      360       370       380       390       400       410        
pF1KA1 KLVLRWYLSGFYKKPKGIKKPYNPILGETFRCCWFHPQTDSRTFYIAEQVSHHPPVSAFH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KLVLRWYLSGFYKKPKGIKKPYNPILGETFRCCWFHPQTDSRTFYIAEQVSHHPPVSAFH
        430       440       450       460       470       480      

      420       430       440       450       460       470        
pF1KA1 VSNRKDGFCISGSITAKSRFYGNSLSALLDGKATLTFLNRAEDYTLTMPYAHCKGILYGT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VSNRKDGFCISGSITAKSRFYGNSLSALLDGKATLTFLNRAEDYTLTMPYAHCKGILYGT
        490       500       510       520       530       540      

      480       490       500       510       520       530        
pF1KA1 MTLELGGKVTIECAKNNFQAQLEFKLKPFFGGSTSINQISGKITSGEEVLASLSGHWDRD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MTLELGGKVTIECAKNNFQAQLEFKLKPFFGGSTSINQISGKITSGEEVLASLSGHWDRD
        550       560       570       580       590       600      

      540       550       560       570       580       590        
pF1KA1 VFIKEEGSGSSALFWTPSGEVRRQRLRQHTVPLEEQTELESERLWQHVTRAISKGDQHRA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VFIKEEGSGSSALFWTPSGEVRRQRLRQHTVPLEEQTELESERLWQHVTRAISKGDQHRA
        610       620       630       640       650       660      

      600       610       620       630       640       650        
pF1KA1 TQEKFALEEAQRQRARERQESLMPWKPQLFHLDPITQEWHYRYEDHSPWDPLKDIAQFEQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TQEKFALEEAQRQRARERQESLMPWKPQLFHLDPITQEWHYRYEDHSPWDPLKDIAQFEQ
        670       680       690       700       710       720      

      660       670       680       690       700       710        
pF1KA1 DGILRTLQQEAVARQTTFLGSPGPRHERSGPDQRLRKASDQPSGHSQATESSGSTPESCP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DGILRTLQQEAVARQTTFLGSPGPRHERSGPDQRLRKASDQPSGHSQATESSGSTPESCP
        730       740       750       760       770       780      

      720       730       740       750       760       770        
pF1KA1 ELSDEEQDGDFVPGGESPCPRCRKEARRLQALHEAILSIREAQQELHRHLSAMLSSTARA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ELSDEEQDGDFVPGGESPCPRCRKEARRLQALHEAILSIREAQQELHRHLSAMLSSTARA
        790       800       810       820       830       840      

      780       790       800       810 
pF1KA1 AQAPTPGLLQSPRSWFLLCVFLACQLFINHILK
       :::::::::::::::::::::::::::::::::
XP_011 AQAPTPGLLQSPRSWFLLCVFLACQLFINHILK
        850       860       870         

>--
 initn: 241 init1: 241 opt: 241  Z-score: 204.5  bits: 48.9 E(85289): 0.00012
Smith-Waterman score: 241; 100.0% identity (100.0% similar) in 36 aa overlap (1-36:1-36)

               10        20        30        40        50        60
pF1KA1 MKEEAFLRRRFSLCPPSSTPQKVDPRKLTRNLLLSGDNELYPLSPGKDMEPNGPSLPRDE
       ::::::::::::::::::::::::::::::::::::                        
XP_011 MKEEAFLRRRFSLCPPSSTPQKVDPRKLTRNLLLSGDNELYPLSPGKDMEPNGPSLPRDE
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KA1 GPPTPSSATKVPPAEYRLCNGSDKECVSPTARVTKKETLKAQKENYRQEKKRATRQLLSA
                                                                   
XP_011 GPPTPSSATKVPPAEYRLCNGSDKECVSPTARVTKKETLKAQKENYRQEKKRATRQLLSA
               70        80        90       100       110       120

>>NP_065947 (OMIM: 606733) oxysterol-binding protein-rel  (879 aa)
 initn: 4599 init1: 4599 opt: 4599  Z-score: 3820.2  bits: 717.9 E(85289): 4.8e-206
Smith-Waterman score: 5098; 91.9% identity (91.9% similar) in 843 aa overlap (37-811:37-879)

         10        20        30        40        50        60      
pF1KA1 LRRRFSLCPPSSTPQKVDPRKLTRNLLLSGDNELYPLSPGKDMEPNGPSLPRDEGPPTPS
                                     ::::::::::::::::::::::::::::::
NP_065 LRRRFSLCPPSSTPQKVDPRKLTRNLLLSGDNELYPLSPGKDMEPNGPSLPRDEGPPTPS
         10        20        30        40        50        60      

         70        80        90       100       110       120      
pF1KA1 SATKVPPAEYRLCNGSDKECVSPTARVTKKETLKAQKENYRQEKKRATRQLLSALTDPSV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_065 SATKVPPAEYRLCNGSDKECVSPTARVTKKETLKAQKENYRQEKKRATRQLLSALTDPSV
         70        80        90       100       110       120      

        130                                                        
pF1KA1 VIMADSLK----------------------------------------------------
       ::::::::                                                    
NP_065 VIMADSLKIRGTLKSWTKLWCVLKPGVLLIYKTPKVGQWVGTVLLHCCELIERPSKKDGF
        130       140       150       160       170       180      

                          140       150       160       170        
pF1KA1 ----------------GPKGESVGSITQPLPSSYLIFRAASESDGRCWLDALELALRCSS
                       ::::::::::::::::::::::::::::::::::::::::::::
NP_065 CFKLFHPLDQSVWAVKGPKGESVGSITQPLPSSYLIFRAASESDGRCWLDALELALRCSS
        190       200       210       220       230       240      

      180       190       200       210       220       230        
pF1KA1 LLRLGTCKPGRDGEPGTSPDASPSSLCGLPASATVHPDQDLFPLNGSSLENDAFSDKSER
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_065 LLRLGTCKPGRDGEPGTSPDASPSSLCGLPASATVHPDQDLFPLNGSSLENDAFSDKSER
        250       260       270       280       290       300      

      240       250       260       270       280       290        
pF1KA1 ENPEESDTETQDHSRKTESGSDQSETPGAPVRRGTTYVEQVQEELGELGEASQVETVSEE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_065 ENPEESDTETQDHSRKTESGSDQSETPGAPVRRGTTYVEQVQEELGELGEASQVETVSEE
        310       320       330       340       350       360      

      300       310       320       330       340       350        
pF1KA1 NKSLMWTLLKQLRPGMDLSRVVLPTFVLEPRSFLNKLSDYYYHADLLSRAAVEEDAYSRM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_065 NKSLMWTLLKQLRPGMDLSRVVLPTFVLEPRSFLNKLSDYYYHADLLSRAAVEEDAYSRM
        370       380       390       400       410       420      

      360       370       380       390       400       410        
pF1KA1 KLVLRWYLSGFYKKPKGIKKPYNPILGETFRCCWFHPQTDSRTFYIAEQVSHHPPVSAFH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_065 KLVLRWYLSGFYKKPKGIKKPYNPILGETFRCCWFHPQTDSRTFYIAEQVSHHPPVSAFH
        430       440       450       460       470       480      

      420       430       440       450       460       470        
pF1KA1 VSNRKDGFCISGSITAKSRFYGNSLSALLDGKATLTFLNRAEDYTLTMPYAHCKGILYGT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_065 VSNRKDGFCISGSITAKSRFYGNSLSALLDGKATLTFLNRAEDYTLTMPYAHCKGILYGT
        490       500       510       520       530       540      

      480       490       500       510       520       530        
pF1KA1 MTLELGGKVTIECAKNNFQAQLEFKLKPFFGGSTSINQISGKITSGEEVLASLSGHWDRD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_065 MTLELGGKVTIECAKNNFQAQLEFKLKPFFGGSTSINQISGKITSGEEVLASLSGHWDRD
        550       560       570       580       590       600      

      540       550       560       570       580       590        
pF1KA1 VFIKEEGSGSSALFWTPSGEVRRQRLRQHTVPLEEQTELESERLWQHVTRAISKGDQHRA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_065 VFIKEEGSGSSALFWTPSGEVRRQRLRQHTVPLEEQTELESERLWQHVTRAISKGDQHRA
        610       620       630       640       650       660      

      600       610       620       630       640       650        
pF1KA1 TQEKFALEEAQRQRARERQESLMPWKPQLFHLDPITQEWHYRYEDHSPWDPLKDIAQFEQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_065 TQEKFALEEAQRQRARERQESLMPWKPQLFHLDPITQEWHYRYEDHSPWDPLKDIAQFEQ
        670       680       690       700       710       720      

      660       670       680       690       700       710        
pF1KA1 DGILRTLQQEAVARQTTFLGSPGPRHERSGPDQRLRKASDQPSGHSQATESSGSTPESCP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_065 DGILRTLQQEAVARQTTFLGSPGPRHERSGPDQRLRKASDQPSGHSQATESSGSTPESCP
        730       740       750       760       770       780      

      720       730       740       750       760       770        
pF1KA1 ELSDEEQDGDFVPGGESPCPRCRKEARRLQALHEAILSIREAQQELHRHLSAMLSSTARA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_065 ELSDEEQDGDFVPGGESPCPRCRKEARRLQALHEAILSIREAQQELHRHLSAMLSSTARA
        790       800       810       820       830       840      

      780       790       800       810 
pF1KA1 AQAPTPGLLQSPRSWFLLCVFLACQLFINHILK
       :::::::::::::::::::::::::::::::::
NP_065 AQAPTPGLLQSPRSWFLLCVFLACQLFINHILK
        850       860       870         

>--
 initn: 241 init1: 241 opt: 241  Z-score: 204.5  bits: 48.9 E(85289): 0.00012
Smith-Waterman score: 241; 100.0% identity (100.0% similar) in 36 aa overlap (1-36:1-36)

               10        20        30        40        50        60
pF1KA1 MKEEAFLRRRFSLCPPSSTPQKVDPRKLTRNLLLSGDNELYPLSPGKDMEPNGPSLPRDE
       ::::::::::::::::::::::::::::::::::::                        
NP_065 MKEEAFLRRRFSLCPPSSTPQKVDPRKLTRNLLLSGDNELYPLSPGKDMEPNGPSLPRDE
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KA1 GPPTPSSATKVPPAEYRLCNGSDKECVSPTARVTKKETLKAQKENYRQEKKRATRQLLSA
                                                                   
NP_065 GPPTPSSATKVPPAEYRLCNGSDKECVSPTARVTKKETLKAQKENYRQEKKRATRQLLSA
               70        80        90       100       110       120

>>XP_016872653 (OMIM: 606733) PREDICTED: oxysterol-bindi  (509 aa)
 initn: 3476 init1: 3476 opt: 3476  Z-score: 2892.0  bits: 545.4 E(85289): 2.4e-154
Smith-Waterman score: 3476; 100.0% identity (100.0% similar) in 509 aa overlap (303-811:1-509)

            280       290       300       310       320       330  
pF1KA1 TTYVEQVQEELGELGEASQVETVSEENKSLMWTLLKQLRPGMDLSRVVLPTFVLEPRSFL
                                     ::::::::::::::::::::::::::::::
XP_016                               MWTLLKQLRPGMDLSRVVLPTFVLEPRSFL
                                             10        20        30

            340       350       360       370       380       390  
pF1KA1 NKLSDYYYHADLLSRAAVEEDAYSRMKLVLRWYLSGFYKKPKGIKKPYNPILGETFRCCW
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NKLSDYYYHADLLSRAAVEEDAYSRMKLVLRWYLSGFYKKPKGIKKPYNPILGETFRCCW
               40        50        60        70        80        90

            400       410       420       430       440       450  
pF1KA1 FHPQTDSRTFYIAEQVSHHPPVSAFHVSNRKDGFCISGSITAKSRFYGNSLSALLDGKAT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FHPQTDSRTFYIAEQVSHHPPVSAFHVSNRKDGFCISGSITAKSRFYGNSLSALLDGKAT
              100       110       120       130       140       150

            460       470       480       490       500       510  
pF1KA1 LTFLNRAEDYTLTMPYAHCKGILYGTMTLELGGKVTIECAKNNFQAQLEFKLKPFFGGST
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LTFLNRAEDYTLTMPYAHCKGILYGTMTLELGGKVTIECAKNNFQAQLEFKLKPFFGGST
              160       170       180       190       200       210

            520       530       540       550       560       570  
pF1KA1 SINQISGKITSGEEVLASLSGHWDRDVFIKEEGSGSSALFWTPSGEVRRQRLRQHTVPLE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SINQISGKITSGEEVLASLSGHWDRDVFIKEEGSGSSALFWTPSGEVRRQRLRQHTVPLE
              220       230       240       250       260       270

            580       590       600       610       620       630  
pF1KA1 EQTELESERLWQHVTRAISKGDQHRATQEKFALEEAQRQRARERQESLMPWKPQLFHLDP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EQTELESERLWQHVTRAISKGDQHRATQEKFALEEAQRQRARERQESLMPWKPQLFHLDP
              280       290       300       310       320       330

            640       650       660       670       680       690  
pF1KA1 ITQEWHYRYEDHSPWDPLKDIAQFEQDGILRTLQQEAVARQTTFLGSPGPRHERSGPDQR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ITQEWHYRYEDHSPWDPLKDIAQFEQDGILRTLQQEAVARQTTFLGSPGPRHERSGPDQR
              340       350       360       370       380       390

            700       710       720       730       740       750  
pF1KA1 LRKASDQPSGHSQATESSGSTPESCPELSDEEQDGDFVPGGESPCPRCRKEARRLQALHE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LRKASDQPSGHSQATESSGSTPESCPELSDEEQDGDFVPGGESPCPRCRKEARRLQALHE
              400       410       420       430       440       450

            760       770       780       790       800       810 
pF1KA1 AILSIREAQQELHRHLSAMLSSTARAAQAPTPGLLQSPRSWFLLCVFLACQLFINHILK
       :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AILSIREAQQELHRHLSAMLSSTARAAQAPTPGLLQSPRSWFLLCVFLACQLFINHILK
              460       470       480       490       500         

>>NP_001003712 (OMIM: 606736) oxysterol-binding protein-  (847 aa)
 initn: 2265 init1: 1944 opt: 2055  Z-score: 1709.8  bits: 327.3 E(85289): 1.7e-88
Smith-Waterman score: 2511; 50.0% identity (72.5% similar) in 822 aa overlap (74-811:55-847)

            50        60        70        80        90       100   
pF1KA1 SPGKDMEPNGPSLPRDEGPPTPSSATKVPPAEYRLCNGSDKECVSPTARVTKKETLKAQK
                                     .: .: :::.:.  : ....::::.::.::
NP_001 ASPHSQGFERGKEDISQNKDESSLSMSKSKSESKLYNGSEKDS-STSSKLTKKESLKVQK
           30        40        50        60         70        80   

           110       120       130                                 
pF1KA1 ENYRQEKKRATRQLLSALTDPSVVIMAD--------------------------------
       .:::.::::::..:::..:::::..:::                                
NP_001 KNYREEKKRATKELLSTITDPSVIVMADWLKIRGTLKSWTKLWCVLKPGVLLIYKTQKNG
            90       100       110       120       130       140   

                                                 140       150     
pF1KA1 ------------------------------------SLKGPKGESVGSITQPLPSSYLIF
                                           ..::::::.::::::::::::::.
NP_001 QWVGTVLLNACEIIERPSKKDGFCFKLFHPLEQSIWAVKGPKGEAVGSITQPLPSSYLII
           150       160       170       180       190       200   

         160       170       180       190       200       210     
pF1KA1 RAASESDGRCWLDALELALRCSSLLRLGTCKPGRDGEPGTSPDASPSSLCGLPASATVHP
       ::.::::::::.:::::::.:::::.    . :.. . ..: :..  .. ::  . ..: 
NP_001 RATSESDGRCWMDALELALKCSSLLKRTMIREGKEHDLSVSSDSTHVTFYGLLRANNLHS
           210       220       230       240       250       260   

         220             230       240        250       260        
pF1KA1 DQDLFPLNGSSLE------NDAFSDKSERENPEESD-TETQDHSRKTESGSDQSET----
         : : :: : .:      .: .::::..:: .: : ....  ... :: .: ::     
NP_001 G-DNFQLNDSEIERQHFKDQDMYSDKSDKENDQEHDESDNEVMGKSEESDTDTSERQDDS
            270       280       290       300       310       320  

               270       280       290       300       310         
pF1KA1 -----PGAPVRRGTTYVEQVQEELGELGEASQVETVSEENKSLMWTLLKQLRPGMDLSRV
            :  :... :::.:: .::::: :::::.::::::::::.::::::.:::::::.:
NP_001 YIEPEPVEPLKE-TTYTEQSHEELGEAGEASQTETVSEENKSLIWTLLKQVRPGMDLSKV
            330        340       350       360       370       380 

     320       330       340       350       360       370         
pF1KA1 VLPTFVLEPRSFLNKLSDYYYHADLLSRAAVEEDAYSRMKLVLRWYLSGFYKKPKGIKKP
       :::::.:::::::.::::::::::.::.::.::. : :.: :..::::::::::::.:::
NP_001 VLPTFILEPRSFLDKLSDYYYHADFLSEAALEENPYFRLKKVVKWYLSGFYKKPKGLKKP
             390       400       410       420       430       440 

     380       390       400       410       420       430         
pF1KA1 YNPILGETFRCCWFHPQTDSRTFYIAEQVSHHPPVSAFHVSNRKDGFCISGSITAKSRFY
       ::::::::::: :.::.:.:.:::::::::::::.:::.:::::::::.:::: :::.::
NP_001 YNPILGETFRCLWIHPRTNSKTFYIAEQVSHHPPISAFYVSNRKDGFCLSGSILAKSKFY
             450       460       470       480       490       500 

     440       450       460       470       480       490         
pF1KA1 GNSLSALLDGKATLTFLNRAEDYTLTMPYAHCKGILYGTMTLELGGKVTIECAKNNFQAQ
       ::::::.:.:.: ::::::.:::..::::::::::::::::::::: :.: : :....: 
NP_001 GNSLSAILEGEARLTFLNRGEDYVMTMPYAHCKGILYGTMTLELGGTVNITCQKTGYSAI
             510       520       530       540       550       560 

     500       510       520       530       540       550         
pF1KA1 LEFKLKPFFGGSTSINQISGKITSGEEVLASLSGHWDRDVFIKEEGSGSSALFWTPSGEV
       ::::::::.:.:  .::::::.  :.::::.: :::: .::: .. . .: .::.:. ..
NP_001 LEFKLKPFLGSSDCVNQISGKLKLGKEVLATLEGHWDSEVFITDKKTDNSEVFWNPTPDI
             570       580       590       600       610       620 

     560       570       580       590       600       610         
pF1KA1 RRQRLRQHTVPLEEQTELESERLWQHVTRAISKGDQHRATQEKFALEEAQRQRARERQES
       .. :: .::: .::: ..:::.:::.:::::.  :: .:::::..::::::: ::.:. .
NP_001 KQWRLIRHTVKFEEQGDFESEKLWQRVTRAINAKDQTEATQEKYVLEEAQRQAARDRKTK
             630       640       650       660       670       680 

     620       630       640       650       660       670         
pF1KA1 LMPWKPQLFHLDPITQEWHYRYEDHSPWDPLKDIAQFEQDGILRTLQQEAVARQTTFLGS
          :. .::.:::.: ::::.. :  :::::.:. :::.::...:     : ..: ... 
NP_001 NEEWSCKLFELDPLTGEWHYKFADTRPWDPLNDMIQFEKDGVIQT----KVKHRTPMVSV
             690       700       710       720           730       

     680       690       700       710       720       730         
pF1KA1 PGPRHERSGPDQRLRKASDQPSGHSQATESSGSTPESCPELSDEEQDGDFVPGGESPCPR
       :  .:. .  .... :. ..:    :  .::::  .:                  .:  :
NP_001 PKMKHKPTRQQKKVAKGYSSPEPDIQ--DSSGSEAQSV-----------------KPSTR
       740       750       760         770                         

     740       750       760       770       780       790         
pF1KA1 CRKEARRLQALHEAILSIREAQQELHRHLSAMLSSTARAAQAPTPGLLQSPRSWFLLCVF
        ::.. .:  .. .: ::...:.:..:.. :. .  . .. : :  .::. ...:.. ..
NP_001 -RKKGIELGDIQSSIESIKQTQEEIKRNIMALRNHLVSSTPA-TDYFLQQ-KDYFIIFLL
       780       790       800       810        820        830     

     800       810 
pF1KA1 LACQLFINHILK
       .  :..:: ..:
NP_001 ILLQVIINFMFK
         840       

>>NP_001306581 (OMIM: 606736) oxysterol-binding protein-  (847 aa)
 initn: 2265 init1: 1944 opt: 2055  Z-score: 1709.8  bits: 327.3 E(85289): 1.7e-88
Smith-Waterman score: 2511; 50.0% identity (72.5% similar) in 822 aa overlap (74-811:55-847)

            50        60        70        80        90       100   
pF1KA1 SPGKDMEPNGPSLPRDEGPPTPSSATKVPPAEYRLCNGSDKECVSPTARVTKKETLKAQK
                                     .: .: :::.:.  : ....::::.::.::
NP_001 ASPHSQGFERGKEDISQNKDESSLSMSKSKSESKLYNGSEKDS-STSSKLTKKESLKVQK
           30        40        50        60         70        80   

           110       120       130                                 
pF1KA1 ENYRQEKKRATRQLLSALTDPSVVIMAD--------------------------------
       .:::.::::::..:::..:::::..:::                                
NP_001 KNYREEKKRATKELLSTITDPSVIVMADWLKIRGTLKSWTKLWCVLKPGVLLIYKTQKNG
            90       100       110       120       130       140   

                                                 140       150     
pF1KA1 ------------------------------------SLKGPKGESVGSITQPLPSSYLIF
                                           ..::::::.::::::::::::::.
NP_001 QWVGTVLLNACEIIERPSKKDGFCFKLFHPLEQSIWAVKGPKGEAVGSITQPLPSSYLII
           150       160       170       180       190       200   

         160       170       180       190       200       210     
pF1KA1 RAASESDGRCWLDALELALRCSSLLRLGTCKPGRDGEPGTSPDASPSSLCGLPASATVHP
       ::.::::::::.:::::::.:::::.    . :.. . ..: :..  .. ::  . ..: 
NP_001 RATSESDGRCWMDALELALKCSSLLKRTMIREGKEHDLSVSSDSTHVTFYGLLRANNLHS
           210       220       230       240       250       260   

         220             230       240        250       260        
pF1KA1 DQDLFPLNGSSLE------NDAFSDKSERENPEESD-TETQDHSRKTESGSDQSET----
         : : :: : .:      .: .::::..:: .: : ....  ... :: .: ::     
NP_001 G-DNFQLNDSEIERQHFKDQDMYSDKSDKENDQEHDESDNEVMGKSEESDTDTSERQDDS
            270       280       290       300       310       320  

               270       280       290       300       310         
pF1KA1 -----PGAPVRRGTTYVEQVQEELGELGEASQVETVSEENKSLMWTLLKQLRPGMDLSRV
            :  :... :::.:: .::::: :::::.::::::::::.::::::.:::::::.:
NP_001 YIEPEPVEPLKE-TTYTEQSHEELGEAGEASQTETVSEENKSLIWTLLKQVRPGMDLSKV
            330        340       350       360       370       380 

     320       330       340       350       360       370         
pF1KA1 VLPTFVLEPRSFLNKLSDYYYHADLLSRAAVEEDAYSRMKLVLRWYLSGFYKKPKGIKKP
       :::::.:::::::.::::::::::.::.::.::. : :.: :..::::::::::::.:::
NP_001 VLPTFILEPRSFLDKLSDYYYHADFLSEAALEENPYFRLKKVVKWYLSGFYKKPKGLKKP
             390       400       410       420       430       440 

     380       390       400       410       420       430         
pF1KA1 YNPILGETFRCCWFHPQTDSRTFYIAEQVSHHPPVSAFHVSNRKDGFCISGSITAKSRFY
       ::::::::::: :.::.:.:.:::::::::::::.:::.:::::::::.:::: :::.::
NP_001 YNPILGETFRCLWIHPRTNSKTFYIAEQVSHHPPISAFYVSNRKDGFCLSGSILAKSKFY
             450       460       470       480       490       500 

     440       450       460       470       480       490         
pF1KA1 GNSLSALLDGKATLTFLNRAEDYTLTMPYAHCKGILYGTMTLELGGKVTIECAKNNFQAQ
       ::::::.:.:.: ::::::.:::..::::::::::::::::::::: :.: : :....: 
NP_001 GNSLSAILEGEARLTFLNRGEDYVMTMPYAHCKGILYGTMTLELGGTVNITCQKTGYSAI
             510       520       530       540       550       560 

     500       510       520       530       540       550         
pF1KA1 LEFKLKPFFGGSTSINQISGKITSGEEVLASLSGHWDRDVFIKEEGSGSSALFWTPSGEV
       ::::::::.:.:  .::::::.  :.::::.: :::: .::: .. . .: .::.:. ..
NP_001 LEFKLKPFLGSSDCVNQISGKLKLGKEVLATLEGHWDSEVFITDKKTDNSEVFWNPTPDI
             570       580       590       600       610       620 

     560       570       580       590       600       610         
pF1KA1 RRQRLRQHTVPLEEQTELESERLWQHVTRAISKGDQHRATQEKFALEEAQRQRARERQES
       .. :: .::: .::: ..:::.:::.:::::.  :: .:::::..::::::: ::.:. .
NP_001 KQWRLIRHTVKFEEQGDFESEKLWQRVTRAINAKDQTEATQEKYVLEEAQRQAARDRKTK
             630       640       650       660       670       680 

     620       630       640       650       660       670         
pF1KA1 LMPWKPQLFHLDPITQEWHYRYEDHSPWDPLKDIAQFEQDGILRTLQQEAVARQTTFLGS
          :. .::.:::.: ::::.. :  :::::.:. :::.::...:     : ..: ... 
NP_001 NEEWSCKLFELDPLTGEWHYKFADTRPWDPLNDMIQFEKDGVIQT----KVKHRTPMVSV
             690       700       710       720           730       

     680       690       700       710       720       730         
pF1KA1 PGPRHERSGPDQRLRKASDQPSGHSQATESSGSTPESCPELSDEEQDGDFVPGGESPCPR
       :  .:. .  .... :. ..:    :  .::::  .:                  .:  :
NP_001 PKMKHKPTRQQKKVAKGYSSPEPDIQ--DSSGSEAQSV-----------------KPSTR
       740       750       760         770                         

     740       750       760       770       780       790         
pF1KA1 CRKEARRLQALHEAILSIREAQQELHRHLSAMLSSTARAAQAPTPGLLQSPRSWFLLCVF
        ::.. .:  .. .: ::...:.:..:.. :. .  . .. : :  .::. ...:.. ..
NP_001 -RKKGIELGDIQSSIESIKQTQEEIKRNIMALRNHLVSSTPA-TDYFLQQ-KDYFIIFLL
       780       790       800       810        820        830     

     800       810 
pF1KA1 LACQLFINHILK
       .  :..:: ..:
NP_001 ILLQVIINFMFK
         840       

>>XP_006719287 (OMIM: 606736) PREDICTED: oxysterol-bindi  (847 aa)
 initn: 2265 init1: 1944 opt: 2055  Z-score: 1709.8  bits: 327.3 E(85289): 1.7e-88
Smith-Waterman score: 2511; 50.0% identity (72.5% similar) in 822 aa overlap (74-811:55-847)

            50        60        70        80        90       100   
pF1KA1 SPGKDMEPNGPSLPRDEGPPTPSSATKVPPAEYRLCNGSDKECVSPTARVTKKETLKAQK
                                     .: .: :::.:.  : ....::::.::.::
XP_006 ASPHSQGFERGKEDISQNKDESSLSMSKSKSESKLYNGSEKDS-STSSKLTKKESLKVQK
           30        40        50        60         70        80   

           110       120       130                                 
pF1KA1 ENYRQEKKRATRQLLSALTDPSVVIMAD--------------------------------
       .:::.::::::..:::..:::::..:::                                
XP_006 KNYREEKKRATKELLSTITDPSVIVMADWLKIRGTLKSWTKLWCVLKPGVLLIYKTQKNG
            90       100       110       120       130       140   

                                                 140       150     
pF1KA1 ------------------------------------SLKGPKGESVGSITQPLPSSYLIF
                                           ..::::::.::::::::::::::.
XP_006 QWVGTVLLNACEIIERPSKKDGFCFKLFHPLEQSIWAVKGPKGEAVGSITQPLPSSYLII
           150       160       170       180       190       200   

         160       170       180       190       200       210     
pF1KA1 RAASESDGRCWLDALELALRCSSLLRLGTCKPGRDGEPGTSPDASPSSLCGLPASATVHP
       ::.::::::::.:::::::.:::::.    . :.. . ..: :..  .. ::  . ..: 
XP_006 RATSESDGRCWMDALELALKCSSLLKRTMIREGKEHDLSVSSDSTHVTFYGLLRANNLHS
           210       220       230       240       250       260   

         220             230       240        250       260        
pF1KA1 DQDLFPLNGSSLE------NDAFSDKSERENPEESD-TETQDHSRKTESGSDQSET----
         : : :: : .:      .: .::::..:: .: : ....  ... :: .: ::     
XP_006 G-DNFQLNDSEIERQHFKDQDMYSDKSDKENDQEHDESDNEVMGKSEESDTDTSERQDDS
            270       280       290       300       310       320  

               270       280       290       300       310         
pF1KA1 -----PGAPVRRGTTYVEQVQEELGELGEASQVETVSEENKSLMWTLLKQLRPGMDLSRV
            :  :... :::.:: .::::: :::::.::::::::::.::::::.:::::::.:
XP_006 YIEPEPVEPLKE-TTYTEQSHEELGEAGEASQTETVSEENKSLIWTLLKQVRPGMDLSKV
            330        340       350       360       370       380 

     320       330       340       350       360       370         
pF1KA1 VLPTFVLEPRSFLNKLSDYYYHADLLSRAAVEEDAYSRMKLVLRWYLSGFYKKPKGIKKP
       :::::.:::::::.::::::::::.::.::.::. : :.: :..::::::::::::.:::
XP_006 VLPTFILEPRSFLDKLSDYYYHADFLSEAALEENPYFRLKKVVKWYLSGFYKKPKGLKKP
             390       400       410       420       430       440 

     380       390       400       410       420       430         
pF1KA1 YNPILGETFRCCWFHPQTDSRTFYIAEQVSHHPPVSAFHVSNRKDGFCISGSITAKSRFY
       ::::::::::: :.::.:.:.:::::::::::::.:::.:::::::::.:::: :::.::
XP_006 YNPILGETFRCLWIHPRTNSKTFYIAEQVSHHPPISAFYVSNRKDGFCLSGSILAKSKFY
             450       460       470       480       490       500 

     440       450       460       470       480       490         
pF1KA1 GNSLSALLDGKATLTFLNRAEDYTLTMPYAHCKGILYGTMTLELGGKVTIECAKNNFQAQ
       ::::::.:.:.: ::::::.:::..::::::::::::::::::::: :.: : :....: 
XP_006 GNSLSAILEGEARLTFLNRGEDYVMTMPYAHCKGILYGTMTLELGGTVNITCQKTGYSAI
             510       520       530       540       550       560 

     500       510       520       530       540       550         
pF1KA1 LEFKLKPFFGGSTSINQISGKITSGEEVLASLSGHWDRDVFIKEEGSGSSALFWTPSGEV
       ::::::::.:.:  .::::::.  :.::::.: :::: .::: .. . .: .::.:. ..
XP_006 LEFKLKPFLGSSDCVNQISGKLKLGKEVLATLEGHWDSEVFITDKKTDNSEVFWNPTPDI
             570       580       590       600       610       620 

     560       570       580       590       600       610         
pF1KA1 RRQRLRQHTVPLEEQTELESERLWQHVTRAISKGDQHRATQEKFALEEAQRQRARERQES
       .. :: .::: .::: ..:::.:::.:::::.  :: .:::::..::::::: ::.:. .
XP_006 KQWRLIRHTVKFEEQGDFESEKLWQRVTRAINAKDQTEATQEKYVLEEAQRQAARDRKTK
             630       640       650       660       670       680 

     620       630       640       650       660       670         
pF1KA1 LMPWKPQLFHLDPITQEWHYRYEDHSPWDPLKDIAQFEQDGILRTLQQEAVARQTTFLGS
          :. .::.:::.: ::::.. :  :::::.:. :::.::...:     : ..: ... 
XP_006 NEEWSCKLFELDPLTGEWHYKFADTRPWDPLNDMIQFEKDGVIQT----KVKHRTPMVSV
             690       700       710       720           730       

     680       690       700       710       720       730         
pF1KA1 PGPRHERSGPDQRLRKASDQPSGHSQATESSGSTPESCPELSDEEQDGDFVPGGESPCPR
       :  .:. .  .... :. ..:    :  .::::  .:                  .:  :
XP_006 PKMKHKPTRQQKKVAKGYSSPEPDIQ--DSSGSEAQSV-----------------KPSTR
       740       750       760         770                         

     740       750       760       770       780       790         
pF1KA1 CRKEARRLQALHEAILSIREAQQELHRHLSAMLSSTARAAQAPTPGLLQSPRSWFLLCVF
        ::.. .:  .. .: ::...:.:..:.. :. .  . .. : :  .::. ...:.. ..
XP_006 -RKKGIELGDIQSSIESIKQTQEEIKRNIMALRNHLVSSTPA-TDYFLQQ-KDYFIIFLL
       780       790       800       810        820        830     

     800       810 
pF1KA1 LACQLFINHILK
       .  :..:: ..:
XP_006 ILLQVIINFMFK
         840       

>>NP_001306584 (OMIM: 606736) oxysterol-binding protein-  (864 aa)
 initn: 2350 init1: 1944 opt: 2055  Z-score: 1709.7  bits: 327.3 E(85289): 1.7e-88
Smith-Waterman score: 2511; 50.0% identity (72.5% similar) in 822 aa overlap (74-811:72-864)

            50        60        70        80        90       100   
pF1KA1 SPGKDMEPNGPSLPRDEGPPTPSSATKVPPAEYRLCNGSDKECVSPTARVTKKETLKAQK
                                     .: .: :::.:.  : ....::::.::.::
NP_001 LSPSLPGFERGKEDISQNKDESSLSMSKSKSESKLYNGSEKDS-STSSKLTKKESLKVQK
              50        60        70        80         90       100

           110       120       130                                 
pF1KA1 ENYRQEKKRATRQLLSALTDPSVVIMAD--------------------------------
       .:::.::::::..:::..:::::..:::                                
NP_001 KNYREEKKRATKELLSTITDPSVIVMADWLKIRGTLKSWTKLWCVLKPGVLLIYKTQKNG
              110       120       130       140       150       160

                                                 140       150     
pF1KA1 ------------------------------------SLKGPKGESVGSITQPLPSSYLIF
                                           ..::::::.::::::::::::::.
NP_001 QWVGTVLLNACEIIERPSKKDGFCFKLFHPLEQSIWAVKGPKGEAVGSITQPLPSSYLII
              170       180       190       200       210       220

         160       170       180       190       200       210     
pF1KA1 RAASESDGRCWLDALELALRCSSLLRLGTCKPGRDGEPGTSPDASPSSLCGLPASATVHP
       ::.::::::::.:::::::.:::::.    . :.. . ..: :..  .. ::  . ..: 
NP_001 RATSESDGRCWMDALELALKCSSLLKRTMIREGKEHDLSVSSDSTHVTFYGLLRANNLHS
              230       240       250       260       270       280

         220             230       240        250       260        
pF1KA1 DQDLFPLNGSSLE------NDAFSDKSERENPEESD-TETQDHSRKTESGSDQSET----
         : : :: : .:      .: .::::..:: .: : ....  ... :: .: ::     
NP_001 G-DNFQLNDSEIERQHFKDQDMYSDKSDKENDQEHDESDNEVMGKSEESDTDTSERQDDS
               290       300       310       320       330         

               270       280       290       300       310         
pF1KA1 -----PGAPVRRGTTYVEQVQEELGELGEASQVETVSEENKSLMWTLLKQLRPGMDLSRV
            :  :... :::.:: .::::: :::::.::::::::::.::::::.:::::::.:
NP_001 YIEPEPVEPLKE-TTYTEQSHEELGEAGEASQTETVSEENKSLIWTLLKQVRPGMDLSKV
     340       350        360       370       380       390        

     320       330       340       350       360       370         
pF1KA1 VLPTFVLEPRSFLNKLSDYYYHADLLSRAAVEEDAYSRMKLVLRWYLSGFYKKPKGIKKP
       :::::.:::::::.::::::::::.::.::.::. : :.: :..::::::::::::.:::
NP_001 VLPTFILEPRSFLDKLSDYYYHADFLSEAALEENPYFRLKKVVKWYLSGFYKKPKGLKKP
      400       410       420       430       440       450        

     380       390       400       410       420       430         
pF1KA1 YNPILGETFRCCWFHPQTDSRTFYIAEQVSHHPPVSAFHVSNRKDGFCISGSITAKSRFY
       ::::::::::: :.::.:.:.:::::::::::::.:::.:::::::::.:::: :::.::
NP_001 YNPILGETFRCLWIHPRTNSKTFYIAEQVSHHPPISAFYVSNRKDGFCLSGSILAKSKFY
      460       470       480       490       500       510        

     440       450       460       470       480       490         
pF1KA1 GNSLSALLDGKATLTFLNRAEDYTLTMPYAHCKGILYGTMTLELGGKVTIECAKNNFQAQ
       ::::::.:.:.: ::::::.:::..::::::::::::::::::::: :.: : :....: 
NP_001 GNSLSAILEGEARLTFLNRGEDYVMTMPYAHCKGILYGTMTLELGGTVNITCQKTGYSAI
      520       530       540       550       560       570        

     500       510       520       530       540       550         
pF1KA1 LEFKLKPFFGGSTSINQISGKITSGEEVLASLSGHWDRDVFIKEEGSGSSALFWTPSGEV
       ::::::::.:.:  .::::::.  :.::::.: :::: .::: .. . .: .::.:. ..
NP_001 LEFKLKPFLGSSDCVNQISGKLKLGKEVLATLEGHWDSEVFITDKKTDNSEVFWNPTPDI
      580       590       600       610       620       630        

     560       570       580       590       600       610         
pF1KA1 RRQRLRQHTVPLEEQTELESERLWQHVTRAISKGDQHRATQEKFALEEAQRQRARERQES
       .. :: .::: .::: ..:::.:::.:::::.  :: .:::::..::::::: ::.:. .
NP_001 KQWRLIRHTVKFEEQGDFESEKLWQRVTRAINAKDQTEATQEKYVLEEAQRQAARDRKTK
      640       650       660       670       680       690        

     620       630       640       650       660       670         
pF1KA1 LMPWKPQLFHLDPITQEWHYRYEDHSPWDPLKDIAQFEQDGILRTLQQEAVARQTTFLGS
          :. .::.:::.: ::::.. :  :::::.:. :::.::...:     : ..: ... 
NP_001 NEEWSCKLFELDPLTGEWHYKFADTRPWDPLNDMIQFEKDGVIQT----KVKHRTPMVSV
      700       710       720       730       740           750    

     680       690       700       710       720       730         
pF1KA1 PGPRHERSGPDQRLRKASDQPSGHSQATESSGSTPESCPELSDEEQDGDFVPGGESPCPR
       :  .:. .  .... :. ..:    :  .::::  .:                  .:  :
NP_001 PKMKHKPTRQQKKVAKGYSSPEPDIQ--DSSGSEAQSV-----------------KPSTR
          760       770       780         790                      

     740       750       760       770       780       790         
pF1KA1 CRKEARRLQALHEAILSIREAQQELHRHLSAMLSSTARAAQAPTPGLLQSPRSWFLLCVF
        ::.. .:  .. .: ::...:.:..:.. :. .  . .. : :  .::. ...:.. ..
NP_001 -RKKGIELGDIQSSIESIKQTQEEIKRNIMALRNHLVSSTPA-TDYFLQQ-KDYFIIFLL
          800       810       820       830        840        850  

     800       810 
pF1KA1 LACQLFINHILK
       .  :..:: ..:
NP_001 ILLQVIINFMFK
            860    




811 residues in 1 query   sequences
60827320 residues in 85289 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Fri Nov  4 01:36:32 2016 done: Fri Nov  4 01:36:34 2016
 Total Scan time: 14.950 Total Display time:  0.260

Function used was FASTA [36.3.4 Apr, 2011]
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