Result of FASTA (omim) for pF1KB7852
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KB7852, 614 aa
  1>>>pF1KB7852 614 - 614 aa - 614 aa
Library: /omim/omim.rfq.tfa
  60827320 residues in 85289 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 5.8088+/-0.000386; mu= 16.9469+/- 0.024
 mean_var=81.9650+/-16.139, 0's: 0 Z-trim(114.0): 198  B-trim: 214 in 1/53
 Lambda= 0.141664
 statistics sampled from 23433 (23644) to 23433 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.639), E-opt: 0.2 (0.277), width:  16
 Scan time:  9.300

The best scores are:                                      opt bits E(85289)
NP_001317488 (OMIM: 617135) lethal(3)malignant bra ( 614) 4300 888.9       0
XP_011524062 (OMIM: 617135) PREDICTED: lethal(3)ma ( 642) 3955 818.4       0
XP_006722427 (OMIM: 617135) PREDICTED: lethal(3)ma ( 485) 3434 711.9 1.3e-204
XP_011524064 (OMIM: 617135) PREDICTED: lethal(3)ma ( 567) 3430 711.1 2.5e-204
XP_011524065 (OMIM: 617135) PREDICTED: lethal(3)ma ( 521) 3429 710.9 2.7e-204
XP_011524067 (OMIM: 617135) PREDICTED: lethal(3)ma ( 497) 3428 710.7  3e-204
NP_775735 (OMIM: 617135) lethal(3)malignant brain  ( 623) 3428 710.7 3.6e-204
XP_011524063 (OMIM: 617135) PREDICTED: lethal(3)ma ( 623) 3428 710.7 3.6e-204
XP_011524061 (OMIM: 617135) PREDICTED: lethal(3)ma ( 651) 3428 710.7 3.8e-204
XP_011524060 (OMIM: 617135) PREDICTED: lethal(3)ma ( 651) 3428 710.7 3.8e-204
XP_011524059 (OMIM: 617135) PREDICTED: lethal(3)ma ( 651) 3428 710.7 3.8e-204
XP_016881564 (OMIM: 617135) PREDICTED: lethal(3)ma ( 488) 3277 679.8 5.8e-195
XP_016881565 (OMIM: 617135) PREDICTED: lethal(3)ma ( 488) 3277 679.8 5.8e-195
XP_016881563 (OMIM: 617135) PREDICTED: lethal(3)ma ( 574) 3277 679.9 6.6e-195
XP_016881566 (OMIM: 617135) PREDICTED: lethal(3)ma ( 370) 2625 546.5  6e-155
NP_056293 (OMIM: 608802) lethal(3)malignant brain  ( 772) 1916 401.8 4.6e-111
NP_115479 (OMIM: 608802) lethal(3)malignant brain  ( 840) 1916 401.8 4.9e-111
XP_011524069 (OMIM: 617135) PREDICTED: lethal(3)ma ( 362) 1364 288.8 2.3e-77
XP_016884468 (OMIM: 611865) PREDICTED: lethal(3)ma ( 495)  674 147.8 8.2e-35
XP_016884467 (OMIM: 611865) PREDICTED: lethal(3)ma ( 495)  674 147.8 8.2e-35
XP_016884466 (OMIM: 611865) PREDICTED: lethal(3)ma ( 595)  674 147.9 9.6e-35
XP_011528723 (OMIM: 611865) PREDICTED: lethal(3)ma ( 614)  674 147.9 9.8e-35
XP_016884465 (OMIM: 611865) PREDICTED: lethal(3)ma ( 621)  674 147.9 9.9e-35
XP_011528722 (OMIM: 611865) PREDICTED: lethal(3)ma ( 687)  674 147.9 1.1e-34
NP_113676 (OMIM: 611865) lethal(3)malignant brain  ( 705)  674 147.9 1.1e-34
XP_016884469 (OMIM: 611865) PREDICTED: lethal(3)ma ( 408)  668 146.5 1.6e-34
XP_006724521 (OMIM: 300208) PREDICTED: sex comb on ( 609)  636 140.1 2.1e-32
XP_016884710 (OMIM: 300208) PREDICTED: sex comb on ( 609)  636 140.1 2.1e-32
XP_016884708 (OMIM: 300208) PREDICTED: sex comb on ( 700)  636 140.1 2.4e-32
NP_006080 (OMIM: 300208) sex comb on midleg-like p ( 700)  636 140.1 2.4e-32
XP_016884709 (OMIM: 300208) PREDICTED: sex comb on ( 700)  636 140.1 2.4e-32
XP_011539342 (OMIM: 616396) PREDICTED: polycomb pr ( 523)  580 128.6 5.2e-29
XP_011539341 (OMIM: 616396) PREDICTED: polycomb pr ( 550)  580 128.6 5.5e-29
XP_016856187 (OMIM: 616396) PREDICTED: polycomb pr ( 618)  580 128.7   6e-29
XP_011539336 (OMIM: 616396) PREDICTED: polycomb pr ( 621)  580 128.7   6e-29
NP_001165690 (OMIM: 616396) polycomb protein SCMH1 ( 648)  580 128.7 6.2e-29
XP_011539335 (OMIM: 616396) PREDICTED: polycomb pr ( 660)  580 128.7 6.3e-29
NP_001026864 (OMIM: 616396) polycomb protein SCMH1 ( 660)  580 128.7 6.3e-29
XP_011539334 (OMIM: 616396) PREDICTED: polycomb pr ( 670)  580 128.7 6.4e-29
XP_006710525 (OMIM: 616396) PREDICTED: polycomb pr ( 670)  580 128.7 6.4e-29
XP_016856189 (OMIM: 616396) PREDICTED: polycomb pr ( 564)  519 116.2 3.2e-25
NP_036368 (OMIM: 616396) polycomb protein SCMH1 is ( 591)  519 116.2 3.3e-25
XP_011539337 (OMIM: 616396) PREDICTED: polycomb pr ( 613)  519 116.2 3.4e-25
XP_016856201 (OMIM: 616396) PREDICTED: polycomb pr ( 457)  489 110.0 1.9e-23
XP_016856200 (OMIM: 616396) PREDICTED: polycomb pr ( 457)  489 110.0 1.9e-23
XP_016856197 (OMIM: 616396) PREDICTED: polycomb pr ( 479)  489 110.0 1.9e-23
NP_001165691 (OMIM: 616396) polycomb protein SCMH1 ( 577)  489 110.0 2.3e-23
NP_001165689 (OMIM: 616396) polycomb protein SCMH1 ( 577)  489 110.0 2.3e-23
NP_001165692 (OMIM: 616396) polycomb protein SCMH1 ( 599)  489 110.1 2.3e-23
XP_011539338 (OMIM: 616396) PREDICTED: polycomb pr ( 599)  489 110.1 2.3e-23


>>NP_001317488 (OMIM: 617135) lethal(3)malignant brain t  (614 aa)
 initn: 4300 init1: 4300 opt: 4300  Z-score: 4749.7  bits: 888.9 E(85289):    0
Smith-Waterman score: 4300; 100.0% identity (100.0% similar) in 614 aa overlap (1-614:1-614)

               10        20        30        40        50        60
pF1KB7 MKQPNRKRKLNMDSKERLDQDGRLEQAEEEKKPKDSTTPLSHVPSAAAQGAWSWEWYLKE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MKQPNRKRKLNMDSKERLDQDGRLEQAEEEKKPKDSTTPLSHVPSAAAQGAWSWEWYLKE
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB7 QKAVAAPVELFSKDQSFPEHENGFQIGMRLEGIDPRHPSVFCVLSVAEVCGYRLRLHFDG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QKAVAAPVELFSKDQSFPEHENGFQIGMRLEGIDPRHPSVFCVLSVAEVCGYRLRLHFDG
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB7 YLSCYDFWTNAGSPDIHPVGWCEKTKHELHIPKGYRKDKFVWMDYLKACKLQNAPKKLFR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 YLSCYDFWTNAGSPDIHPVGWCEKTKHELHIPKGYRKDKFVWMDYLKACKLQNAPKKLFR
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB7 NRSPNGPMSKEFQVGMKLEAVDRKNPSLVCVATIADIVEDRLLVHFDNWDDSYDYWCDVN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NRSPNGPMSKEFQVGMKLEAVDRKNPSLVCVATIADIVEDRLLVHFDNWDDSYDYWCDVN
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB7 SPYVQPVGWCQENGRTLIAPQGYPNPENFSWTEYLEATQTNAVPAKVFKMRLPHGFLPNM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SPYVQPVGWCQENGRTLIAPQGYPNPENFSWTEYLEATQTNAVPAKVFKMRLPHGFLPNM
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KB7 KLEVVDKRNPRLIRVATIVDVDDQRVKVHFDGWDHKYDYWVEADSPDIHPIGWCDVTGHP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KLEVVDKRNPRLIRVATIVDVDDQRVKVHFDGWDHKYDYWVEADSPDIHPIGWCDVTGHP
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KB7 LEVPQRTNDLKILPGQAVCPTPGCRGIGHIRGPRYSGHHSAFGCPYSDMNLKKEATLHDR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LEVPQRTNDLKILPGQAVCPTPGCRGIGHIRGPRYSGHHSAFGCPYSDMNLKKEATLHDR
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KB7 LREQTQANLESDSSHSKSKSLCSLNFNGKHEKVNSQPRLVQQAKCLKIKGKEDIDLDNLF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LREQTQANLESDSSHSKSKSLCSLNFNGKHEKVNSQPRLVQQAKCLKIKGKEDIDLDNLF
              430       440       450       460       470       480

              490       500       510       520       530       540
pF1KB7 REYSVEQAQQVLHQSVSMSTVSAHPFRDLPLGREQHCKLLPGVADIRASQVARWTVDEVA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 REYSVEQAQQVLHQSVSMSTVSAHPFRDLPLGREQHCKLLPGVADIRASQVARWTVDEVA
              490       500       510       520       530       540

              550       560       570       580       590       600
pF1KB7 EFVQSLLGCEEHAKCFKKEQIDGKAFLLLTQTDIVKVMKIKLGPALKIYNSILMFRHSQE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EFVQSLLGCEEHAKCFKKEQIDGKAFLLLTQTDIVKVMKIKLGPALKIYNSILMFRHSQE
              550       560       570       580       590       600

              610    
pF1KB7 LPEEDIASGQEVRG
       ::::::::::::::
NP_001 LPEEDIASGQEVRG
              610    

>>XP_011524062 (OMIM: 617135) PREDICTED: lethal(3)malign  (642 aa)
 initn: 4502 init1: 3955 opt: 3955  Z-score: 4368.3  bits: 818.4 E(85289):    0
Smith-Waterman score: 3955; 99.8% identity (100.0% similar) in 560 aa overlap (1-560:1-560)

               10        20        30        40        50        60
pF1KB7 MKQPNRKRKLNMDSKERLDQDGRLEQAEEEKKPKDSTTPLSHVPSAAAQGAWSWEWYLKE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MKQPNRKRKLNMDSKERLDQDGRLEQAEEEKKPKDSTTPLSHVPSAAAQGAWSWEWYLKE
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB7 QKAVAAPVELFSKDQSFPEHENGFQIGMRLEGIDPRHPSVFCVLSVAEVCGYRLRLHFDG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QKAVAAPVELFSKDQSFPEHENGFQIGMRLEGIDPRHPSVFCVLSVAEVCGYRLRLHFDG
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB7 YLSCYDFWTNAGSPDIHPVGWCEKTKHELHIPKGYRKDKFVWMDYLKACKLQNAPKKLFR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 YLSCYDFWTNAGSPDIHPVGWCEKTKHELHIPKGYRKDKFVWMDYLKACKLQNAPKKLFR
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB7 NRSPNGPMSKEFQVGMKLEAVDRKNPSLVCVATIADIVEDRLLVHFDNWDDSYDYWCDVN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NRSPNGPMSKEFQVGMKLEAVDRKNPSLVCVATIADIVEDRLLVHFDNWDDSYDYWCDVN
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB7 SPYVQPVGWCQENGRTLIAPQGYPNPENFSWTEYLEATQTNAVPAKVFKMRLPHGFLPNM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SPYVQPVGWCQENGRTLIAPQGYPNPENFSWTEYLEATQTNAVPAKVFKMRLPHGFLPNM
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KB7 KLEVVDKRNPRLIRVATIVDVDDQRVKVHFDGWDHKYDYWVEADSPDIHPIGWCDVTGHP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KLEVVDKRNPRLIRVATIVDVDDQRVKVHFDGWDHKYDYWVEADSPDIHPIGWCDVTGHP
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KB7 LEVPQRTNDLKILPGQAVCPTPGCRGIGHIRGPRYSGHHSAFGCPYSDMNLKKEATLHDR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LEVPQRTNDLKILPGQAVCPTPGCRGIGHIRGPRYSGHHSAFGCPYSDMNLKKEATLHDR
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KB7 LREQTQANLESDSSHSKSKSLCSLNFNGKHEKVNSQPRLVQQAKCLKIKGKEDIDLDNLF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LREQTQANLESDSSHSKSKSLCSLNFNGKHEKVNSQPRLVQQAKCLKIKGKEDIDLDNLF
              430       440       450       460       470       480

              490       500       510       520       530       540
pF1KB7 REYSVEQAQQVLHQSVSMSTVSAHPFRDLPLGREQHCKLLPGVADIRASQVARWTVDEVA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 REYSVEQAQQVLHQSVSMSTVSAHPFRDLPLGREQHCKLLPGVADIRASQVARWTVDEVA
              490       500       510       520       530       540

              550       560       570       580       590       600
pF1KB7 EFVQSLLGCEEHAKCFKKEQIDGKAFLLLTQTDIVKVMKIKLGPALKIYNSILMFRHSQE
       :::::::::::::::::::.                                        
XP_011 EFVQSLLGCEEHAKCFKKEESSEPGCVNQRRCSSPWSCAEVTGASRSWGKQPTRWPLPSS
              550       560       570       580       590       600

>>XP_006722427 (OMIM: 617135) PREDICTED: lethal(3)malign  (485 aa)
 initn: 3981 init1: 3434 opt: 3434  Z-score: 3794.6  bits: 711.9 E(85289): 1.3e-204
Smith-Waterman score: 3434; 99.4% identity (99.8% similar) in 485 aa overlap (1-485:1-485)

               10        20        30        40        50        60
pF1KB7 MKQPNRKRKLNMDSKERLDQDGRLEQAEEEKKPKDSTTPLSHVPSAAAQGAWSWEWYLKE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 MKQPNRKRKLNMDSKERLDQDGRLEQAEEEKKPKDSTTPLSHVPSAAAQGAWSWEWYLKE
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB7 QKAVAAPVELFSKDQSFPEHENGFQIGMRLEGIDPRHPSVFCVLSVAEVCGYRLRLHFDG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 QKAVAAPVELFSKDQSFPEHENGFQIGMRLEGIDPRHPSVFCVLSVAEVCGYRLRLHFDG
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB7 YLSCYDFWTNAGSPDIHPVGWCEKTKHELHIPKGYRKDKFVWMDYLKACKLQNAPKKLFR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 YLSCYDFWTNAGSPDIHPVGWCEKTKHELHIPKGYRKDKFVWMDYLKACKLQNAPKKLFR
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB7 NRSPNGPMSKEFQVGMKLEAVDRKNPSLVCVATIADIVEDRLLVHFDNWDDSYDYWCDVN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 NRSPNGPMSKEFQVGMKLEAVDRKNPSLVCVATIADIVEDRLLVHFDNWDDSYDYWCDVN
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB7 SPYVQPVGWCQENGRTLIAPQGYPNPENFSWTEYLEATQTNAVPAKVFKMRLPHGFLPNM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 SPYVQPVGWCQENGRTLIAPQGYPNPENFSWTEYLEATQTNAVPAKVFKMRLPHGFLPNM
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KB7 KLEVVDKRNPRLIRVATIVDVDDQRVKVHFDGWDHKYDYWVEADSPDIHPIGWCDVTGHP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 KLEVVDKRNPRLIRVATIVDVDDQRVKVHFDGWDHKYDYWVEADSPDIHPIGWCDVTGHP
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KB7 LEVPQRTNDLKILPGQAVCPTPGCRGIGHIRGPRYSGHHSAFGCPYSDMNLKKEATLHDR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 LEVPQRTNDLKILPGQAVCPTPGCRGIGHIRGPRYSGHHSAFGCPYSDMNLKKEATLHDR
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KB7 LREQTQANLESDSSHSKSKSLCSLNFNGKHEKVNSQPRLVQQAKCLKIKGKEDIDLDNLF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 LREQTQANLESDSSHSKSKSLCSLNFNGKHEKVNSQPRLVQQAKCLKIKGKEDIDLDNLF
              430       440       450       460       470       480

              490       500       510       520       530       540
pF1KB7 REYSVEQAQQVLHQSVSMSTVSAHPFRDLPLGREQHCKLLPGVADIRASQVARWTVDEVA
       :. .:                                                       
XP_006 RDGTV                                                       
                                                                   

>>XP_011524064 (OMIM: 617135) PREDICTED: lethal(3)malign  (567 aa)
 initn: 3429 init1: 3429 opt: 3430  Z-score: 3789.2  bits: 711.1 E(85289): 2.5e-204
Smith-Waterman score: 3430; 94.9% identity (96.9% similar) in 513 aa overlap (1-510:1-511)

               10        20        30        40        50        60
pF1KB7 MKQPNRKRKLNMDSKERLDQDGRLEQAEEEKKPKDSTTPLSHVPSAAAQGAWSWEWYLKE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MKQPNRKRKLNMDSKERLDQDGRLEQAEEEKKPKDSTTPLSHVPSAAAQGAWSWEWYLKE
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB7 QKAVAAPVELFSKDQSFPEHENGFQIGMRLEGIDPRHPSVFCVLSVAEVCGYRLRLHFDG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QKAVAAPVELFSKDQSFPEHENGFQIGMRLEGIDPRHPSVFCVLSVAEVCGYRLRLHFDG
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB7 YLSCYDFWTNAGSPDIHPVGWCEKTKHELHIPKGYRKDKFVWMDYLKACKLQNAPKKLFR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 YLSCYDFWTNAGSPDIHPVGWCEKTKHELHIPKGYRKDKFVWMDYLKACKLQNAPKKLFR
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB7 NRSPNGPMSKEFQVGMKLEAVDRKNPSLVCVATIADIVEDRLLVHFDNWDDSYDYWCDVN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NRSPNGPMSKEFQVGMKLEAVDRKNPSLVCVATIADIVEDRLLVHFDNWDDSYDYWCDVN
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB7 SPYVQPVGWCQENGRTLIAPQGYPNPENFSWTEYLEATQTNAVPAKVFKMRLPHGFLPNM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SPYVQPVGWCQENGRTLIAPQGYPNPENFSWTEYLEATQTNAVPAKVFKMRLPHGFLPNM
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KB7 KLEVVDKRNPRLIRVATIVDVDDQRVKVHFDGWDHKYDYWVEADSPDIHPIGWCDVTGHP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KLEVVDKRNPRLIRVATIVDVDDQRVKVHFDGWDHKYDYWVEADSPDIHPIGWCDVTGHP
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KB7 LEVPQRTNDLKILPGQAVCPTPGCRGIGHIRGPRYSGHHSAFGCPYSDMNLKKEATLHDR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LEVPQRTNDLKILPGQAVCPTPGCRGIGHIRGPRYSGHHSAFGCPYSDMNLKKEATLHDR
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KB7 LREQTQANLESDSSHSKSKSLCSLNFNGKHEKVNSQPRLVQQAKCLKIKGKEDIDLDNLF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LREQTQANLESDSSHSKSKSLCSLNFNGKHEKVNSQPRLVQQAKCLKIKGKEDIDLDNLF
              430       440       450       460       470       480

              490          500       510       520       530       
pF1KB7 REYSVEQAQQV---LHQSVSMSTVSAHPFRDLPLGREQHCKLLPGVADIRASQVARWTVD
       :   .: .  .   .:.  . : . ..: . ::                           
XP_011 RGTRLEGVTTLNTTFHS--NKSGACGQPRQRLPWSIPEITLSNWSLSLTHPLLHTDTVSG
              490         500       510       520       530        

       540       550       560       570       580       590       
pF1KB7 EVAEFVQSLLGCEEHAKCFKKEQIDGKAFLLLTQTDIVKVMKIKLGPALKIYNSILMFRH
                                                                   
XP_011 YNRMQLHLSTSLQTRCVISPSDTAAGIVI                               
      540       550       560                                      

>>XP_011524065 (OMIM: 617135) PREDICTED: lethal(3)malign  (521 aa)
 initn: 3976 init1: 3429 opt: 3429  Z-score: 3788.7  bits: 710.9 E(85289): 2.7e-204
Smith-Waterman score: 3429; 99.6% identity (99.8% similar) in 483 aa overlap (1-483:1-483)

               10        20        30        40        50        60
pF1KB7 MKQPNRKRKLNMDSKERLDQDGRLEQAEEEKKPKDSTTPLSHVPSAAAQGAWSWEWYLKE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MKQPNRKRKLNMDSKERLDQDGRLEQAEEEKKPKDSTTPLSHVPSAAAQGAWSWEWYLKE
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB7 QKAVAAPVELFSKDQSFPEHENGFQIGMRLEGIDPRHPSVFCVLSVAEVCGYRLRLHFDG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QKAVAAPVELFSKDQSFPEHENGFQIGMRLEGIDPRHPSVFCVLSVAEVCGYRLRLHFDG
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB7 YLSCYDFWTNAGSPDIHPVGWCEKTKHELHIPKGYRKDKFVWMDYLKACKLQNAPKKLFR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 YLSCYDFWTNAGSPDIHPVGWCEKTKHELHIPKGYRKDKFVWMDYLKACKLQNAPKKLFR
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB7 NRSPNGPMSKEFQVGMKLEAVDRKNPSLVCVATIADIVEDRLLVHFDNWDDSYDYWCDVN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NRSPNGPMSKEFQVGMKLEAVDRKNPSLVCVATIADIVEDRLLVHFDNWDDSYDYWCDVN
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB7 SPYVQPVGWCQENGRTLIAPQGYPNPENFSWTEYLEATQTNAVPAKVFKMRLPHGFLPNM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SPYVQPVGWCQENGRTLIAPQGYPNPENFSWTEYLEATQTNAVPAKVFKMRLPHGFLPNM
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KB7 KLEVVDKRNPRLIRVATIVDVDDQRVKVHFDGWDHKYDYWVEADSPDIHPIGWCDVTGHP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KLEVVDKRNPRLIRVATIVDVDDQRVKVHFDGWDHKYDYWVEADSPDIHPIGWCDVTGHP
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KB7 LEVPQRTNDLKILPGQAVCPTPGCRGIGHIRGPRYSGHHSAFGCPYSDMNLKKEATLHDR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LEVPQRTNDLKILPGQAVCPTPGCRGIGHIRGPRYSGHHSAFGCPYSDMNLKKEATLHDR
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KB7 LREQTQANLESDSSHSKSKSLCSLNFNGKHEKVNSQPRLVQQAKCLKIKGKEDIDLDNLF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LREQTQANLESDSSHSKSKSLCSLNFNGKHEKVNSQPRLVQQAKCLKIKGKEDIDLDNLF
              430       440       450       460       470       480

              490       500       510       520       530       540
pF1KB7 REYSVEQAQQVLHQSVSMSTVSAHPFRDLPLGREQHCKLLPGVADIRASQVARWTVDEVA
       : .                                                         
XP_011 RAHLQPWQLCTFVSPGRCRRSVCLLEGRNIAELSTDLVEVQ                   
              490       500       510       520                    

>>XP_011524067 (OMIM: 617135) PREDICTED: lethal(3)malign  (497 aa)
 initn: 3428 init1: 3428 opt: 3428  Z-score: 3787.9  bits: 710.7 E(85289): 3e-204
Smith-Waterman score: 3428; 100.0% identity (100.0% similar) in 481 aa overlap (1-481:1-481)

               10        20        30        40        50        60
pF1KB7 MKQPNRKRKLNMDSKERLDQDGRLEQAEEEKKPKDSTTPLSHVPSAAAQGAWSWEWYLKE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MKQPNRKRKLNMDSKERLDQDGRLEQAEEEKKPKDSTTPLSHVPSAAAQGAWSWEWYLKE
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB7 QKAVAAPVELFSKDQSFPEHENGFQIGMRLEGIDPRHPSVFCVLSVAEVCGYRLRLHFDG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QKAVAAPVELFSKDQSFPEHENGFQIGMRLEGIDPRHPSVFCVLSVAEVCGYRLRLHFDG
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB7 YLSCYDFWTNAGSPDIHPVGWCEKTKHELHIPKGYRKDKFVWMDYLKACKLQNAPKKLFR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 YLSCYDFWTNAGSPDIHPVGWCEKTKHELHIPKGYRKDKFVWMDYLKACKLQNAPKKLFR
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB7 NRSPNGPMSKEFQVGMKLEAVDRKNPSLVCVATIADIVEDRLLVHFDNWDDSYDYWCDVN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NRSPNGPMSKEFQVGMKLEAVDRKNPSLVCVATIADIVEDRLLVHFDNWDDSYDYWCDVN
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB7 SPYVQPVGWCQENGRTLIAPQGYPNPENFSWTEYLEATQTNAVPAKVFKMRLPHGFLPNM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SPYVQPVGWCQENGRTLIAPQGYPNPENFSWTEYLEATQTNAVPAKVFKMRLPHGFLPNM
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KB7 KLEVVDKRNPRLIRVATIVDVDDQRVKVHFDGWDHKYDYWVEADSPDIHPIGWCDVTGHP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KLEVVDKRNPRLIRVATIVDVDDQRVKVHFDGWDHKYDYWVEADSPDIHPIGWCDVTGHP
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KB7 LEVPQRTNDLKILPGQAVCPTPGCRGIGHIRGPRYSGHHSAFGCPYSDMNLKKEATLHDR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LEVPQRTNDLKILPGQAVCPTPGCRGIGHIRGPRYSGHHSAFGCPYSDMNLKKEATLHDR
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KB7 LREQTQANLESDSSHSKSKSLCSLNFNGKHEKVNSQPRLVQQAKCLKIKGKEDIDLDNLF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LREQTQANLESDSSHSKSKSLCSLNFNGKHEKVNSQPRLVQQAKCLKIKGKEDIDLDNLF
              430       440       450       460       470       480

              490       500       510       520       530       540
pF1KB7 REYSVEQAQQVLHQSVSMSTVSAHPFRDLPLGREQHCKLLPGVADIRASQVARWTVDEVA
       :                                                           
XP_011 RGNGRKSLTRSQKRLVF                                           
              490                                                  

>>NP_775735 (OMIM: 617135) lethal(3)malignant brain tumo  (623 aa)
 initn: 4286 init1: 3428 opt: 3428  Z-score: 3786.4  bits: 710.7 E(85289): 3.6e-204
Smith-Waterman score: 4272; 98.6% identity (98.6% similar) in 623 aa overlap (1-614:1-623)

               10        20        30        40        50        60
pF1KB7 MKQPNRKRKLNMDSKERLDQDGRLEQAEEEKKPKDSTTPLSHVPSAAAQGAWSWEWYLKE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_775 MKQPNRKRKLNMDSKERLDQDGRLEQAEEEKKPKDSTTPLSHVPSAAAQGAWSWEWYLKE
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB7 QKAVAAPVELFSKDQSFPEHENGFQIGMRLEGIDPRHPSVFCVLSVAEVCGYRLRLHFDG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_775 QKAVAAPVELFSKDQSFPEHENGFQIGMRLEGIDPRHPSVFCVLSVAEVCGYRLRLHFDG
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB7 YLSCYDFWTNAGSPDIHPVGWCEKTKHELHIPKGYRKDKFVWMDYLKACKLQNAPKKLFR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_775 YLSCYDFWTNAGSPDIHPVGWCEKTKHELHIPKGYRKDKFVWMDYLKACKLQNAPKKLFR
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB7 NRSPNGPMSKEFQVGMKLEAVDRKNPSLVCVATIADIVEDRLLVHFDNWDDSYDYWCDVN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_775 NRSPNGPMSKEFQVGMKLEAVDRKNPSLVCVATIADIVEDRLLVHFDNWDDSYDYWCDVN
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB7 SPYVQPVGWCQENGRTLIAPQGYPNPENFSWTEYLEATQTNAVPAKVFKMRLPHGFLPNM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_775 SPYVQPVGWCQENGRTLIAPQGYPNPENFSWTEYLEATQTNAVPAKVFKMRLPHGFLPNM
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KB7 KLEVVDKRNPRLIRVATIVDVDDQRVKVHFDGWDHKYDYWVEADSPDIHPIGWCDVTGHP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_775 KLEVVDKRNPRLIRVATIVDVDDQRVKVHFDGWDHKYDYWVEADSPDIHPIGWCDVTGHP
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KB7 LEVPQRTNDLKILPGQAVCPTPGCRGIGHIRGPRYSGHHSAFGCPYSDMNLKKEATLHDR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_775 LEVPQRTNDLKILPGQAVCPTPGCRGIGHIRGPRYSGHHSAFGCPYSDMNLKKEATLHDR
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KB7 LREQTQANLESDSSHSKSKSLCSLNFNGKHEKVNSQPRLVQQAKCLKIKGKEDIDLDNLF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_775 LREQTQANLESDSSHSKSKSLCSLNFNGKHEKVNSQPRLVQQAKCLKIKGKEDIDLDNLF
              430       440       450       460       470       480

                       490       500       510       520       530 
pF1KB7 R---------EYSVEQAQQVLHQSVSMSTVSAHPFRDLPLGREQHCKLLPGVADIRASQV
       :         ::::::::::::::::::::::::::::::::::::::::::::::::::
NP_775 RVLVLHPRGLEYSVEQAQQVLHQSVSMSTVSAHPFRDLPLGREQHCKLLPGVADIRASQV
              490       500       510       520       530       540

             540       550       560       570       580       590 
pF1KB7 ARWTVDEVAEFVQSLLGCEEHAKCFKKEQIDGKAFLLLTQTDIVKVMKIKLGPALKIYNS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_775 ARWTVDEVAEFVQSLLGCEEHAKCFKKEQIDGKAFLLLTQTDIVKVMKIKLGPALKIYNS
              550       560       570       580       590       600

             600       610    
pF1KB7 ILMFRHSQELPEEDIASGQEVRG
       :::::::::::::::::::::::
NP_775 ILMFRHSQELPEEDIASGQEVRG
              610       620   

>>XP_011524063 (OMIM: 617135) PREDICTED: lethal(3)malign  (623 aa)
 initn: 4286 init1: 3428 opt: 3428  Z-score: 3786.4  bits: 710.7 E(85289): 3.6e-204
Smith-Waterman score: 4272; 98.6% identity (98.6% similar) in 623 aa overlap (1-614:1-623)

               10        20        30        40        50        60
pF1KB7 MKQPNRKRKLNMDSKERLDQDGRLEQAEEEKKPKDSTTPLSHVPSAAAQGAWSWEWYLKE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MKQPNRKRKLNMDSKERLDQDGRLEQAEEEKKPKDSTTPLSHVPSAAAQGAWSWEWYLKE
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB7 QKAVAAPVELFSKDQSFPEHENGFQIGMRLEGIDPRHPSVFCVLSVAEVCGYRLRLHFDG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QKAVAAPVELFSKDQSFPEHENGFQIGMRLEGIDPRHPSVFCVLSVAEVCGYRLRLHFDG
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB7 YLSCYDFWTNAGSPDIHPVGWCEKTKHELHIPKGYRKDKFVWMDYLKACKLQNAPKKLFR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 YLSCYDFWTNAGSPDIHPVGWCEKTKHELHIPKGYRKDKFVWMDYLKACKLQNAPKKLFR
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB7 NRSPNGPMSKEFQVGMKLEAVDRKNPSLVCVATIADIVEDRLLVHFDNWDDSYDYWCDVN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NRSPNGPMSKEFQVGMKLEAVDRKNPSLVCVATIADIVEDRLLVHFDNWDDSYDYWCDVN
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB7 SPYVQPVGWCQENGRTLIAPQGYPNPENFSWTEYLEATQTNAVPAKVFKMRLPHGFLPNM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SPYVQPVGWCQENGRTLIAPQGYPNPENFSWTEYLEATQTNAVPAKVFKMRLPHGFLPNM
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KB7 KLEVVDKRNPRLIRVATIVDVDDQRVKVHFDGWDHKYDYWVEADSPDIHPIGWCDVTGHP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KLEVVDKRNPRLIRVATIVDVDDQRVKVHFDGWDHKYDYWVEADSPDIHPIGWCDVTGHP
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KB7 LEVPQRTNDLKILPGQAVCPTPGCRGIGHIRGPRYSGHHSAFGCPYSDMNLKKEATLHDR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LEVPQRTNDLKILPGQAVCPTPGCRGIGHIRGPRYSGHHSAFGCPYSDMNLKKEATLHDR
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KB7 LREQTQANLESDSSHSKSKSLCSLNFNGKHEKVNSQPRLVQQAKCLKIKGKEDIDLDNLF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LREQTQANLESDSSHSKSKSLCSLNFNGKHEKVNSQPRLVQQAKCLKIKGKEDIDLDNLF
              430       440       450       460       470       480

                       490       500       510       520       530 
pF1KB7 R---------EYSVEQAQQVLHQSVSMSTVSAHPFRDLPLGREQHCKLLPGVADIRASQV
       :         ::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RVLVLHPRGLEYSVEQAQQVLHQSVSMSTVSAHPFRDLPLGREQHCKLLPGVADIRASQV
              490       500       510       520       530       540

             540       550       560       570       580       590 
pF1KB7 ARWTVDEVAEFVQSLLGCEEHAKCFKKEQIDGKAFLLLTQTDIVKVMKIKLGPALKIYNS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ARWTVDEVAEFVQSLLGCEEHAKCFKKEQIDGKAFLLLTQTDIVKVMKIKLGPALKIYNS
              550       560       570       580       590       600

             600       610    
pF1KB7 ILMFRHSQELPEEDIASGQEVRG
       :::::::::::::::::::::::
XP_011 ILMFRHSQELPEEDIASGQEVRG
              610       620   

>>XP_011524061 (OMIM: 617135) PREDICTED: lethal(3)malign  (651 aa)
 initn: 3941 init1: 3428 opt: 3428  Z-score: 3786.1  bits: 710.7 E(85289): 3.8e-204
Smith-Waterman score: 3927; 98.2% identity (98.4% similar) in 569 aa overlap (1-560:1-569)

               10        20        30        40        50        60
pF1KB7 MKQPNRKRKLNMDSKERLDQDGRLEQAEEEKKPKDSTTPLSHVPSAAAQGAWSWEWYLKE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MKQPNRKRKLNMDSKERLDQDGRLEQAEEEKKPKDSTTPLSHVPSAAAQGAWSWEWYLKE
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB7 QKAVAAPVELFSKDQSFPEHENGFQIGMRLEGIDPRHPSVFCVLSVAEVCGYRLRLHFDG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QKAVAAPVELFSKDQSFPEHENGFQIGMRLEGIDPRHPSVFCVLSVAEVCGYRLRLHFDG
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB7 YLSCYDFWTNAGSPDIHPVGWCEKTKHELHIPKGYRKDKFVWMDYLKACKLQNAPKKLFR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 YLSCYDFWTNAGSPDIHPVGWCEKTKHELHIPKGYRKDKFVWMDYLKACKLQNAPKKLFR
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB7 NRSPNGPMSKEFQVGMKLEAVDRKNPSLVCVATIADIVEDRLLVHFDNWDDSYDYWCDVN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NRSPNGPMSKEFQVGMKLEAVDRKNPSLVCVATIADIVEDRLLVHFDNWDDSYDYWCDVN
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB7 SPYVQPVGWCQENGRTLIAPQGYPNPENFSWTEYLEATQTNAVPAKVFKMRLPHGFLPNM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SPYVQPVGWCQENGRTLIAPQGYPNPENFSWTEYLEATQTNAVPAKVFKMRLPHGFLPNM
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KB7 KLEVVDKRNPRLIRVATIVDVDDQRVKVHFDGWDHKYDYWVEADSPDIHPIGWCDVTGHP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KLEVVDKRNPRLIRVATIVDVDDQRVKVHFDGWDHKYDYWVEADSPDIHPIGWCDVTGHP
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KB7 LEVPQRTNDLKILPGQAVCPTPGCRGIGHIRGPRYSGHHSAFGCPYSDMNLKKEATLHDR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LEVPQRTNDLKILPGQAVCPTPGCRGIGHIRGPRYSGHHSAFGCPYSDMNLKKEATLHDR
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KB7 LREQTQANLESDSSHSKSKSLCSLNFNGKHEKVNSQPRLVQQAKCLKIKGKEDIDLDNLF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LREQTQANLESDSSHSKSKSLCSLNFNGKHEKVNSQPRLVQQAKCLKIKGKEDIDLDNLF
              430       440       450       460       470       480

                       490       500       510       520       530 
pF1KB7 R---------EYSVEQAQQVLHQSVSMSTVSAHPFRDLPLGREQHCKLLPGVADIRASQV
       :         ::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RVLVLHPRGLEYSVEQAQQVLHQSVSMSTVSAHPFRDLPLGREQHCKLLPGVADIRASQV
              490       500       510       520       530       540

             540       550       560       570       580       590 
pF1KB7 ARWTVDEVAEFVQSLLGCEEHAKCFKKEQIDGKAFLLLTQTDIVKVMKIKLGPALKIYNS
       ::::::::::::::::::::::::::::.                               
XP_011 ARWTVDEVAEFVQSLLGCEEHAKCFKKEESSEPGCVNQRRCSSPWSCAEVTGASRSWGKQ
              550       560       570       580       590       600

>>XP_011524060 (OMIM: 617135) PREDICTED: lethal(3)malign  (651 aa)
 initn: 3941 init1: 3428 opt: 3428  Z-score: 3786.1  bits: 710.7 E(85289): 3.8e-204
Smith-Waterman score: 3927; 98.2% identity (98.4% similar) in 569 aa overlap (1-560:1-569)

               10        20        30        40        50        60
pF1KB7 MKQPNRKRKLNMDSKERLDQDGRLEQAEEEKKPKDSTTPLSHVPSAAAQGAWSWEWYLKE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MKQPNRKRKLNMDSKERLDQDGRLEQAEEEKKPKDSTTPLSHVPSAAAQGAWSWEWYLKE
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB7 QKAVAAPVELFSKDQSFPEHENGFQIGMRLEGIDPRHPSVFCVLSVAEVCGYRLRLHFDG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QKAVAAPVELFSKDQSFPEHENGFQIGMRLEGIDPRHPSVFCVLSVAEVCGYRLRLHFDG
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB7 YLSCYDFWTNAGSPDIHPVGWCEKTKHELHIPKGYRKDKFVWMDYLKACKLQNAPKKLFR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 YLSCYDFWTNAGSPDIHPVGWCEKTKHELHIPKGYRKDKFVWMDYLKACKLQNAPKKLFR
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB7 NRSPNGPMSKEFQVGMKLEAVDRKNPSLVCVATIADIVEDRLLVHFDNWDDSYDYWCDVN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NRSPNGPMSKEFQVGMKLEAVDRKNPSLVCVATIADIVEDRLLVHFDNWDDSYDYWCDVN
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB7 SPYVQPVGWCQENGRTLIAPQGYPNPENFSWTEYLEATQTNAVPAKVFKMRLPHGFLPNM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SPYVQPVGWCQENGRTLIAPQGYPNPENFSWTEYLEATQTNAVPAKVFKMRLPHGFLPNM
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KB7 KLEVVDKRNPRLIRVATIVDVDDQRVKVHFDGWDHKYDYWVEADSPDIHPIGWCDVTGHP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KLEVVDKRNPRLIRVATIVDVDDQRVKVHFDGWDHKYDYWVEADSPDIHPIGWCDVTGHP
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KB7 LEVPQRTNDLKILPGQAVCPTPGCRGIGHIRGPRYSGHHSAFGCPYSDMNLKKEATLHDR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LEVPQRTNDLKILPGQAVCPTPGCRGIGHIRGPRYSGHHSAFGCPYSDMNLKKEATLHDR
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KB7 LREQTQANLESDSSHSKSKSLCSLNFNGKHEKVNSQPRLVQQAKCLKIKGKEDIDLDNLF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LREQTQANLESDSSHSKSKSLCSLNFNGKHEKVNSQPRLVQQAKCLKIKGKEDIDLDNLF
              430       440       450       460       470       480

                       490       500       510       520       530 
pF1KB7 R---------EYSVEQAQQVLHQSVSMSTVSAHPFRDLPLGREQHCKLLPGVADIRASQV
       :         ::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RVLVLHPRGLEYSVEQAQQVLHQSVSMSTVSAHPFRDLPLGREQHCKLLPGVADIRASQV
              490       500       510       520       530       540

             540       550       560       570       580       590 
pF1KB7 ARWTVDEVAEFVQSLLGCEEHAKCFKKEQIDGKAFLLLTQTDIVKVMKIKLGPALKIYNS
       ::::::::::::::::::::::::::::.                               
XP_011 ARWTVDEVAEFVQSLLGCEEHAKCFKKEESSEPGCVNQRRCSSPWSCAEVTGASRSWGKQ
              550       560       570       580       590       600




614 residues in 1 query   sequences
60827320 residues in 85289 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Sat Nov  5 09:54:57 2016 done: Sat Nov  5 09:54:59 2016
 Total Scan time:  9.300 Total Display time:  0.150

Function used was FASTA [36.3.4 Apr, 2011]
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