Result of FASTA (omim) for
pF1KB9493
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB9493, 197 aa
1>>>pF1KB9493 197 - 197 aa - 197 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 6.4328+/-0.000399; mu= 7.7915+/- 0.024
mean_var=164.7436+/-36.432, 0's: 0 Z-trim(116.8): 464 B-trim: 898 in 2/51
Lambda= 0.099924
statistics sampled from 27490 (28219) to 27490 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.718), E-opt: 0.2 (0.331), width: 16
Scan time: 6.480
The best scores are: opt bits E(85289)
NP_060832 (OMIM: 612332) protein lin-7 homolog C [ ( 197) 1263 193.7 1.6e-49
NP_071448 (OMIM: 612331) protein lin-7 homolog B i ( 207) 1109 171.5 7.9e-43
NP_004655 (OMIM: 603380) protein lin-7 homolog A i ( 233) 1039 161.5 9.3e-40
NP_001311352 (OMIM: 603380) protein lin-7 homolog ( 162) 795 126.2 2.9e-29
XP_011537230 (OMIM: 603380) PREDICTED: protein lin ( 186) 778 123.8 1.7e-28
XP_006723386 (OMIM: 612331) PREDICTED: protein lin ( 183) 737 117.9 1e-26
NP_001295348 (OMIM: 612331) protein lin-7 homolog ( 137) 406 70.0 2e-12
XP_016882620 (OMIM: 612331) PREDICTED: protein lin ( 105) 302 54.9 5.4e-08
NP_066943 (OMIM: 300189,300850) disks large homolo ( 817) 266 50.7 7.4e-06
XP_006724689 (OMIM: 300189,300850) PREDICTED: disk ( 831) 266 50.7 7.4e-06
XP_011529185 (OMIM: 300189,300850) PREDICTED: disk ( 835) 266 50.7 7.5e-06
XP_006724688 (OMIM: 300189,300850) PREDICTED: disk ( 849) 266 50.7 7.5e-06
XP_016884813 (OMIM: 300189,300850) PREDICTED: disk ( 480) 262 49.9 7.8e-06
XP_016884812 (OMIM: 300189,300850) PREDICTED: disk ( 494) 262 49.9 7.9e-06
XP_016884811 (OMIM: 300189,300850) PREDICTED: disk ( 498) 262 49.9 8e-06
NP_065781 (OMIM: 300189,300850) disks large homolo ( 512) 262 49.9 8.1e-06
NP_001308006 (OMIM: 602887) disks large homolog 4 ( 664) 255 49.0 1.9e-05
NP_001308005 (OMIM: 602887) disks large homolog 4 ( 664) 255 49.0 1.9e-05
XP_011522004 (OMIM: 602887) PREDICTED: disks large ( 664) 255 49.0 1.9e-05
XP_016879779 (OMIM: 602887) PREDICTED: disks large ( 697) 255 49.1 2e-05
XP_016879778 (OMIM: 602887) PREDICTED: disks large ( 699) 255 49.1 2e-05
XP_016879777 (OMIM: 602887) PREDICTED: disks large ( 702) 255 49.1 2e-05
XP_016861313 (OMIM: 601014) PREDICTED: disks large ( 519) 253 48.6 2e-05
NP_001122299 (OMIM: 602887) disks large homolog 4 ( 721) 255 49.1 2e-05
NP_001308004 (OMIM: 602887) disks large homolog 4 ( 724) 255 49.1 2e-05
XP_005256548 (OMIM: 602887) PREDICTED: disks large ( 754) 255 49.1 2.1e-05
NP_001308003 (OMIM: 602887) disks large homolog 4 ( 764) 255 49.1 2.1e-05
NP_001356 (OMIM: 602887) disks large homolog 4 iso ( 767) 255 49.1 2.1e-05
XP_011522001 (OMIM: 602887) PREDICTED: disks large ( 797) 255 49.1 2.2e-05
XP_011522000 (OMIM: 602887) PREDICTED: disks large ( 797) 255 49.1 2.2e-05
NP_001017408 (OMIM: 606845) Golgi-associated PDZ a ( 454) 245 47.4 4.1e-05
NP_065132 (OMIM: 606845) Golgi-associated PDZ and ( 462) 245 47.4 4.2e-05
XP_016855490 (OMIM: 603199) PREDICTED: inaD-like p ( 992) 241 47.2 0.0001
XP_011532543 (OMIM: 602625) PREDICTED: membrane-as ( 746) 237 46.5 0.00013
XP_011532542 (OMIM: 602625) PREDICTED: membrane-as ( 774) 237 46.5 0.00013
XP_016855489 (OMIM: 603199) PREDICTED: inaD-like p (1634) 241 47.5 0.00014
XP_016855488 (OMIM: 603199) PREDICTED: inaD-like p (1854) 241 47.5 0.00015
XP_016855487 (OMIM: 603199) PREDICTED: inaD-like p (1879) 241 47.6 0.00015
XP_005270398 (OMIM: 603199) PREDICTED: inaD-like p (1882) 241 47.6 0.00015
XP_011538768 (OMIM: 603199) PREDICTED: inaD-like p (1907) 241 47.6 0.00015
XP_011538767 (OMIM: 603199) PREDICTED: inaD-like p (1912) 241 47.6 0.00015
XP_011538766 (OMIM: 603199) PREDICTED: inaD-like p (1921) 241 47.6 0.00015
XP_011538764 (OMIM: 603199) PREDICTED: inaD-like p (1937) 241 47.6 0.00016
XP_011538765 (OMIM: 603199) PREDICTED: inaD-like p (1937) 241 47.6 0.00016
XP_016862997 (OMIM: 602625) PREDICTED: membrane-as (1168) 237 46.7 0.00017
XP_016862996 (OMIM: 602625) PREDICTED: membrane-as (1224) 237 46.8 0.00017
NP_004733 (OMIM: 602625) membrane-associated guany (1256) 237 46.8 0.00018
XP_016862995 (OMIM: 602625) PREDICTED: membrane-as (1276) 237 46.8 0.00018
NP_056335 (OMIM: 602625) membrane-associated guany (1287) 237 46.8 0.00018
XP_005265631 (OMIM: 602625) PREDICTED: membrane-as (1288) 237 46.8 0.00018
>>NP_060832 (OMIM: 612332) protein lin-7 homolog C [Homo (197 aa)
initn: 1263 init1: 1263 opt: 1263 Z-score: 1010.1 bits: 193.7 E(85289): 1.6e-49
Smith-Waterman score: 1263; 100.0% identity (100.0% similar) in 197 aa overlap (1-197:1-197)
10 20 30 40 50 60
pF1KB9 MAALGEPVRLERDICRAIELLEKLQRSGEVPPQKLQALQRVLQSEFCNAVREVYEHVYET
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_060 MAALGEPVRLERDICRAIELLEKLQRSGEVPPQKLQALQRVLQSEFCNAVREVYEHVYET
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB9 VDISSSPEVRANATAKATVAAFAASEGHSHPRVVELPKTEEGLGFNIMGGKEQNSPIYIS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_060 VDISSSPEVRANATAKATVAAFAASEGHSHPRVVELPKTEEGLGFNIMGGKEQNSPIYIS
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB9 RIIPGGIADRHGGLKRGDQLLSVNGVSVEGEHHEKAVELLKAAQGKVKLVVRYTPKVLEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_060 RIIPGGIADRHGGLKRGDQLLSVNGVSVEGEHHEKAVELLKAAQGKVKLVVRYTPKVLEE
130 140 150 160 170 180
190
pF1KB9 MESRFEKMRSAKRRQQT
:::::::::::::::::
NP_060 MESRFEKMRSAKRRQQT
190
>>NP_071448 (OMIM: 612331) protein lin-7 homolog B isofo (207 aa)
initn: 1109 init1: 1109 opt: 1109 Z-score: 889.9 bits: 171.5 E(85289): 7.9e-43
Smith-Waterman score: 1109; 84.7% identity (98.0% similar) in 196 aa overlap (1-196:1-196)
10 20 30 40 50 60
pF1KB9 MAALGEPVRLERDICRAIELLEKLQRSGEVPPQKLQALQRVLQSEFCNAVREVYEHVYET
:::: ::. ::::. ::.::::.::::::.::::::::::::::.::.:.:::::..:.:
NP_071 MAALVEPLGLERDVSRAVELLERLQRSGELPPQKLQALQRVLQSRFCSAIREVYEQLYDT
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB9 VDISSSPEVRANATAKATVAAFAASEGHSHPRVVELPKTEEGLGFNIMGGKEQNSPIYIS
.::..: :.::.::::::::::.:::::.::::::::::.::::::::::::::::::::
NP_071 LDITGSAEIRAHATAKATVAAFTASEGHAHPRVVELPKTDEGLGFNIMGGKEQNSPIYIS
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB9 RIIPGGIADRHGGLKRGDQLLSVNGVSVEGEHHEKAVELLKAAQGKVKLVVRYTPKVLEE
:.::::.::::::::::::::::::::::::.:::::::::::::.:::::::::.::::
NP_071 RVIPGGVADRHGGLKRGDQLLSVNGVSVEGEQHEKAVELLKAAQGSVKLVVRYTPRVLEE
130 140 150 160 170 180
190
pF1KB9 MESRFEKMRSAKRRQQT
::.::::::::.::::
NP_071 MEARFEKMRSARRRQQHQSYSSLESRG
190 200
>>NP_004655 (OMIM: 603380) protein lin-7 homolog A isofo (233 aa)
initn: 1038 init1: 1038 opt: 1039 Z-score: 834.7 bits: 161.5 E(85289): 9.3e-40
Smith-Waterman score: 1039; 79.3% identity (94.4% similar) in 198 aa overlap (1-196:14-211)
10 20 30 40
pF1KB9 MAALG--EPVRLERDICRAIELLEKLQRSGEVPPQKLQALQRVLQSE
::.: .:. :.::. ::::::::::.::::: .:::.:..:::::
NP_004 MLKPSVTSAPTADMATLTVVQPLTLDRDVARAIELLEKLQESGEVPVHKLQSLKKVLQSE
10 20 30 40 50 60
50 60 70 80 90 100
pF1KB9 FCNAVREVYEHVYETVDISSSPEVRANATAKATVAAFAASEGHSHPRVVELPKTEEGLGF
::.:.::::....::. ... :: :: :::::::::::::::::::::::::::.:::::
NP_004 FCTAIREVYQYMHETITVNGCPEFRARATAKATVAAFAASEGHSHPRVVELPKTDEGLGF
70 80 90 100 110 120
110 120 130 140 150 160
pF1KB9 NIMGGKEQNSPIYISRIIPGGIADRHGGLKRGDQLLSVNGVSVEGEHHEKAVELLKAAQG
:.:::::::::::::::::::.:.::::::::::::::::::::::::::::::::::.
NP_004 NVMGGKEQNSPIYISRIIPGGVAERHGGLKRGDQLLSVNGVSVEGEHHEKAVELLKAAKD
130 140 150 160 170 180
170 180 190
pF1KB9 KVKLVVRYTPKVLEEMESRFEKMRSAKRRQQT
.::::::::::::::::.::::.:.:.::::
NP_004 SVKLVVRYTPKVLEEMEARFEKLRTARRRQQQQLLIQQQQQQQQQQTQQNHMS
190 200 210 220 230
>>NP_001311352 (OMIM: 603380) protein lin-7 homolog A is (162 aa)
initn: 795 init1: 795 opt: 795 Z-score: 646.4 bits: 126.2 E(85289): 2.9e-29
Smith-Waterman score: 795; 85.0% identity (96.4% similar) in 140 aa overlap (57-196:1-140)
30 40 50 60 70 80
pF1KB9 SGEVPPQKLQALQRVLQSEFCNAVREVYEHVYETVDISSSPEVRANATAKATVAAFAASE
..::. ... :: :: ::::::::::::::
NP_001 MHETITVNGCPEFRARATAKATVAAFAASE
10 20 30
90 100 110 120 130 140
pF1KB9 GHSHPRVVELPKTEEGLGFNIMGGKEQNSPIYISRIIPGGIADRHGGLKRGDQLLSVNGV
:::::::::::::.::::::.:::::::::::::::::::.:.:::::::::::::::::
NP_001 GHSHPRVVELPKTDEGLGFNVMGGKEQNSPIYISRIIPGGVAERHGGLKRGDQLLSVNGV
40 50 60 70 80 90
150 160 170 180 190
pF1KB9 SVEGEHHEKAVELLKAAQGKVKLVVRYTPKVLEEMESRFEKMRSAKRRQQT
:::::::::::::::::. .::::::::::::::::.::::.:.:.::::
NP_001 SVEGEHHEKAVELLKAAKDSVKLVVRYTPKVLEEMEARFEKLRTARRRQQQQLLIQQQQQ
100 110 120 130 140 150
NP_001 QQQQQTQQNHMS
160
>>XP_011537230 (OMIM: 603380) PREDICTED: protein lin-7 h (186 aa)
initn: 758 init1: 758 opt: 778 Z-score: 632.5 bits: 123.8 E(85289): 1.7e-28
Smith-Waterman score: 778; 75.8% identity (93.5% similar) in 153 aa overlap (1-151:14-166)
10 20 30 40
pF1KB9 MAALG--EPVRLERDICRAIELLEKLQRSGEVPPQKLQALQRVLQSE
::.: .:. :.::. ::::::::::.::::: .:::.:..:::::
XP_011 MLKPSVTSAPTADMATLTVVQPLTLDRDVARAIELLEKLQESGEVPVHKLQSLKKVLQSE
10 20 30 40 50 60
50 60 70 80 90 100
pF1KB9 FCNAVREVYEHVYETVDISSSPEVRANATAKATVAAFAASEGHSHPRVVELPKTEEGLGF
::.:.::::....::. ... :: :: :::::::::::::::::::::::::::.:::::
XP_011 FCTAIREVYQYMHETITVNGCPEFRARATAKATVAAFAASEGHSHPRVVELPKTDEGLGF
70 80 90 100 110 120
110 120 130 140 150 160
pF1KB9 NIMGGKEQNSPIYISRIIPGGIADRHGGLKRGDQLLSVNGVSVEGEHHEKAVELLKAAQG
:.:::::::::::::::::::.:.:::::::::::::::::..::.
XP_011 NVMGGKEQNSPIYISRIIPGGVAERHGGLKRGDQLLSVNGVALEGKLLDQTSDSHKFETV
130 140 150 160 170 180
170 180 190
pF1KB9 KVKLVVRYTPKVLEEMESRFEKMRSAKRRQQT
XP_011 LQNPST
>>XP_006723386 (OMIM: 612331) PREDICTED: protein lin-7 h (183 aa)
initn: 737 init1: 737 opt: 737 Z-score: 600.6 bits: 117.9 E(85289): 1e-26
Smith-Waterman score: 951; 77.0% identity (86.2% similar) in 196 aa overlap (1-196:1-172)
10 20 30 40 50 60
pF1KB9 MAALGEPVRLERDICRAIELLEKLQRSGEVPPQKLQALQRVLQSEFCNAVREVYEHVYET
:::: ::. ::::. ::.::::.::::::.::::::::::::::.::.:.::
XP_006 MAALVEPLGLERDVSRAVELLERLQRSGELPPQKLQALQRVLQSRFCSAIRE--------
10 20 30 40 50
70 80 90 100 110 120
pF1KB9 VDISSSPEVRANATAKATVAAFAASEGHSHPRVVELPKTEEGLGFNIMGGKEQNSPIYIS
::::::.:::::.::::::::::.::::::::::::::::::::
XP_006 ----------------ATVAAFTASEGHAHPRVVELPKTDEGLGFNIMGGKEQNSPIYIS
60 70 80 90
130 140 150 160 170 180
pF1KB9 RIIPGGIADRHGGLKRGDQLLSVNGVSVEGEHHEKAVELLKAAQGKVKLVVRYTPKVLEE
:.::::.::::::::::::::::::::::::.:::::::::::::.:::::::::.::::
XP_006 RVIPGGVADRHGGLKRGDQLLSVNGVSVEGEQHEKAVELLKAAQGSVKLVVRYTPRVLEE
100 110 120 130 140 150
190
pF1KB9 MESRFEKMRSAKRRQQT
::.::::::::.::::
XP_006 MEARFEKMRSARRRQQHQSYSSLESRG
160 170 180
>>NP_001295348 (OMIM: 612331) protein lin-7 homolog B is (137 aa)
initn: 416 init1: 377 opt: 406 Z-score: 344.2 bits: 70.0 E(85289): 2e-12
Smith-Waterman score: 513; 51.5% identity (62.2% similar) in 196 aa overlap (1-196:1-126)
10 20 30 40 50 60
pF1KB9 MAALGEPVRLERDICRAIELLEKLQRSGEVPPQKLQALQRVLQSEFCNAVREVYEHVYET
:::: ::. ::::. ::.::::.::::::.::::::::::::::.::.:.:::::..:.:
NP_001 MAALVEPLGLERDVSRAVELLERLQRSGELPPQKLQALQRVLQSRFCSAIREVYEQLYDT
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB9 VDISSSPEVRANATAKATVAAFAASEGHSHPRVVELPKTEEGLGFNIMGGKEQNSPIYIS
.::..: :.::.::::
NP_001 LDITGSAEIRAHATAK--------------------------------------------
70
130 140 150 160 170 180
pF1KB9 RIIPGGIADRHGGLKRGDQLLSVNGVSVEGEHHEKAVELLKAAQGKVKLVVRYTPKVLEE
:::::.:::::::::::::.:::::::::.::::
NP_001 --------------------------SVEGEQHEKAVELLKAAQGSVKLVVRYTPRVLEE
80 90 100 110
190
pF1KB9 MESRFEKMRSAKRRQQT
::.::::::::.::::
NP_001 MEARFEKMRSARRRQQHQSYSSLESRG
120 130
>>XP_016882620 (OMIM: 612331) PREDICTED: protein lin-7 h (105 aa)
initn: 302 init1: 302 opt: 302 Z-score: 264.5 bits: 54.9 E(85289): 5.4e-08
Smith-Waterman score: 302; 52.1% identity (74.0% similar) in 96 aa overlap (1-96:1-96)
10 20 30 40 50 60
pF1KB9 MAALGEPVRLERDICRAIELLEKLQRSGEVPPQKLQALQRVLQSEFCNAVREVYEHVYET
:::: ::. ::::. ::.::::.::::::.::::::::::::::.::.:.:: ..
XP_016 MAALVEPLGLERDVSRAVELLERLQRSGELPPQKLQALQRVLQSRFCSAIREGWRSWRLP
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB9 VDISSSPEVRANATAKATVAAFAASEGHSHPRVVELPKTEEGLGFNIMGGKEQNSPIYIS
.:::. .. .. : : :: .::....
XP_016 DAAASSPRCMSSFMTRWTSPAAPRSEPMPQPRALRVSSMRRRWSC
70 80 90 100
130 140 150 160 170 180
pF1KB9 RIIPGGIADRHGGLKRGDQLLSVNGVSVEGEHHEKAVELLKAAQGKVKLVVRYTPKVLEE
>>NP_066943 (OMIM: 300189,300850) disks large homolog 3 (817 aa)
initn: 347 init1: 173 opt: 266 Z-score: 226.2 bits: 50.7 E(85289): 7.4e-06
Smith-Waterman score: 266; 36.8% identity (63.2% similar) in 133 aa overlap (57-189:350-481)
30 40 50 60 70 80
pF1KB9 SGEVPPQKLQALQRVLQSEFCNAVREVYEHVYETVDISSSPEVRANATAKATVAAFAASE
: :. . :.: . . .: .
NP_066 MYAPPDYASTFTALADNHISHNSSLGYLGAVESKVSYPAPPQVPPTRYSPIPRHMLAEED
320 330 340 350 360 370
90 100 110 120 130 140
pF1KB9 GHSHPRVVELPKTEEGLGFNIMGGKEQNSPIYISRIIPGGIADRHGGLKRGDQLLSVNGV
.:: . : : ::::::.:: :.. :..: :. :: :: : :.:::..::::::
NP_066 FTREPRKIILHKGSTGLGFNIVGG-EDGEGIFVSFILAGGPADLSGELRRGDRILSVNGV
380 390 400 410 420 430
150 160 170 180 190
pF1KB9 SVEGEHHEKAVELLKAAQGKVKLVVRYTPKVLEEMESRFEKMRSAKRRQQT
.... ::.:. :: : .: .:..: :. ..::... .:
NP_066 NLRNATHEQAAAALKRAGQSVTIVAQYRPEEYSRFESKIHDLREQMMNSSMSSGSGSLRT
440 450 460 470 480 490
NP_066 SEKRSLYVRALFDYDRTRDSCLPSQGLSFSYGDILHVINASDDEWWQARLVTPHGESEQI
500 510 520 530 540 550
>>XP_006724689 (OMIM: 300189,300850) PREDICTED: disks la (831 aa)
initn: 347 init1: 173 opt: 266 Z-score: 226.1 bits: 50.7 E(85289): 7.4e-06
Smith-Waterman score: 266; 36.8% identity (63.2% similar) in 133 aa overlap (57-189:350-481)
30 40 50 60 70 80
pF1KB9 SGEVPPQKLQALQRVLQSEFCNAVREVYEHVYETVDISSSPEVRANATAKATVAAFAASE
: :. . :.: . . .: .
XP_006 MYAPPDYASTFTALADNHISHNSSLGYLGAVESKVSYPAPPQVPPTRYSPIPRHMLAEED
320 330 340 350 360 370
90 100 110 120 130 140
pF1KB9 GHSHPRVVELPKTEEGLGFNIMGGKEQNSPIYISRIIPGGIADRHGGLKRGDQLLSVNGV
.:: . : : ::::::.:: :.. :..: :. :: :: : :.:::..::::::
XP_006 FTREPRKIILHKGSTGLGFNIVGG-EDGEGIFVSFILAGGPADLSGELRRGDRILSVNGV
380 390 400 410 420 430
150 160 170 180 190
pF1KB9 SVEGEHHEKAVELLKAAQGKVKLVVRYTPKVLEEMESRFEKMRSAKRRQQT
.... ::.:. :: : .: .:..: :. ..::... .:
XP_006 NLRNATHEQAAAALKRAGQSVTIVAQYRPEEYSRFESKIHDLREQMMNSSMSSGSGSLRT
440 450 460 470 480 490
XP_006 SEKRSLYVRALFDYDRTRDSCLPSQGLSFSYGDILHVINASDDEWWQARLVTPHGESEQI
500 510 520 530 540 550
197 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Thu Nov 3 23:56:41 2016 done: Thu Nov 3 23:56:42 2016
Total Scan time: 6.480 Total Display time: -0.010
Function used was FASTA [36.3.4 Apr, 2011]