Result of FASTA (omim) for pF1KB9478
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KB9478, 1211 aa
  1>>>pF1KB9478 1211 - 1211 aa - 1211 aa
Library: /omim/omim.rfq.tfa
  60827320 residues in 85289 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 17.9673+/-0.00045; mu= -39.1890+/- 0.028
 mean_var=615.4764+/-126.348, 0's: 0 Z-trim(124.5): 127  B-trim: 0 in 0/62
 Lambda= 0.051697
 statistics sampled from 46040 (46193) to 46040 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.788), E-opt: 0.2 (0.542), width:  16
 Scan time: 19.700

The best scores are:                                      opt bits E(85289)
NP_001300888 (OMIM: 159557) AF4/FMR2 family member (1211) 8058 616.6  3e-175
NP_005926 (OMIM: 159557) AF4/FMR2 family member 1  (1210) 8039 615.2 8.1e-175
XP_005263068 (OMIM: 159557) PREDICTED: AF4/FMR2 fa (1216) 8030 614.5 1.3e-174
XP_011530275 (OMIM: 159557) PREDICTED: AF4/FMR2 fa (1218) 8030 614.5 1.3e-174
NP_001160165 (OMIM: 159557) AF4/FMR2 family member (1218) 8030 614.5 1.3e-174
XP_005263064 (OMIM: 159557) PREDICTED: AF4/FMR2 fa (1218) 8030 614.5 1.3e-174
XP_005263066 (OMIM: 159557) PREDICTED: AF4/FMR2 fa (1217) 8011 613.1 3.4e-174
XP_005263070 (OMIM: 159557) PREDICTED: AF4/FMR2 fa (1057) 6994 537.2 2.1e-151
XP_016863704 (OMIM: 159557) PREDICTED: AF4/FMR2 fa ( 849) 5604 433.5 2.7e-120
NP_001300889 (OMIM: 159557) AF4/FMR2 family member ( 849) 5604 433.5 2.7e-120
XP_016863705 (OMIM: 159557) PREDICTED: AF4/FMR2 fa ( 849) 5604 433.5 2.7e-120
XP_006714650 (OMIM: 604417,616368) PREDICTED: AF4/ (1134) 1609 135.6 1.8e-30
XP_005272020 (OMIM: 604417,616368) PREDICTED: AF4/ (1163) 1581 133.5 7.7e-30
NP_055238 (OMIM: 604417,616368) AF4/FMR2 family me (1163) 1581 133.5 7.7e-30
XP_005272021 (OMIM: 604417,616368) PREDICTED: AF4/ ( 785) 1546 130.9 3.3e-29
XP_011509475 (OMIM: 601464) PREDICTED: AF4/FMR2 fa (1251) 1318 113.9 6.6e-24
NP_001020279 (OMIM: 601464) AF4/FMR2 family member (1251) 1318 113.9 6.6e-24
XP_011509476 (OMIM: 601464) PREDICTED: AF4/FMR2 fa (1251) 1318 113.9 6.6e-24
XP_011509472 (OMIM: 601464) PREDICTED: AF4/FMR2 fa (1303) 1318 113.9 6.9e-24
XP_011509471 (OMIM: 601464) PREDICTED: AF4/FMR2 fa (1250) 1317 113.8 6.9e-24
NP_002276 (OMIM: 601464) AF4/FMR2 family member 3  (1226) 1313 113.5 8.4e-24
XP_005264000 (OMIM: 601464) PREDICTED: AF4/FMR2 fa (1226) 1313 113.5 8.4e-24
XP_011509477 (OMIM: 601464) PREDICTED: AF4/FMR2 fa (1226) 1313 113.5 8.4e-24
XP_011509478 (OMIM: 601464) PREDICTED: AF4/FMR2 fa (1226) 1313 113.5 8.4e-24
XP_011509479 (OMIM: 601464) PREDICTED: AF4/FMR2 fa (1226) 1313 113.5 8.4e-24
XP_011509474 (OMIM: 601464) PREDICTED: AF4/FMR2 fa (1235) 1095 97.3 6.6e-19
XP_011509481 (OMIM: 601464) PREDICTED: AF4/FMR2 fa ( 864) 1082 96.3 9.3e-19
XP_016859576 (OMIM: 601464) PREDICTED: AF4/FMR2 fa ( 861) 1076 95.8 1.3e-18
XP_016859575 (OMIM: 601464) PREDICTED: AF4/FMR2 fa ( 862) 1076 95.8 1.3e-18
XP_011509480 (OMIM: 601464) PREDICTED: AF4/FMR2 fa ( 865) 1076 95.8 1.3e-18
XP_016859574 (OMIM: 601464) PREDICTED: AF4/FMR2 fa ( 894) 1076 95.8 1.3e-18
XP_005264002 (OMIM: 601464) PREDICTED: AF4/FMR2 fa ( 895) 1076 95.8 1.3e-18
XP_011509473 (OMIM: 601464) PREDICTED: AF4/FMR2 fa (1235) 1027 92.2 2.2e-17
NP_002016 (OMIM: 300806,309548) AF4/FMR2 family me (1311)  780 73.8 8.3e-12
NP_001162593 (OMIM: 300806,309548) AF4/FMR2 family (1276)  772 73.2 1.2e-11
NP_001164099 (OMIM: 300806,309548) AF4/FMR2 family ( 952)  761 72.3 1.6e-11
NP_001162596 (OMIM: 300806,309548) AF4/FMR2 family (1272)  751 71.6 3.6e-11
NP_001162595 (OMIM: 300806,309548) AF4/FMR2 family (1276)  751 71.6 3.6e-11
NP_001162594 (OMIM: 300806,309548) AF4/FMR2 family (1301)  751 71.6 3.7e-11
NP_001121182 (OMIM: 208250,604283) proteoglycan 4  (1270)  436 48.1 0.00042
XP_016855492 (OMIM: 208250,604283) PREDICTED: prot (1270)  436 48.1 0.00042
XP_016855491 (OMIM: 208250,604283) PREDICTED: prot (1311)  436 48.1 0.00044
NP_001121181 (OMIM: 208250,604283) proteoglycan 4  (1311)  436 48.1 0.00044
NP_001290161 (OMIM: 208250,604283) proteoglycan 4  (1361)  436 48.1 0.00045


>>NP_001300888 (OMIM: 159557) AF4/FMR2 family member 1 i  (1211 aa)
 initn: 8058 init1: 8058 opt: 8058  Z-score: 3267.2  bits: 616.6 E(85289): 3e-175
Smith-Waterman score: 8058; 100.0% identity (100.0% similar) in 1211 aa overlap (1-1211:1-1211)

               10        20        30        40        50        60
pF1KB9 MAAQSSLYNDDRNLLRIREKERRNQEAHQEKEAFPEKIPLFGEPYKTAKGDELSSRIQNM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MAAQSSLYNDDRNLLRIREKERRNQEAHQEKEAFPEKIPLFGEPYKTAKGDELSSRIQNM
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB9 LGNYEEVKEFLSTKSHTHRLDASENRLGKPKYPLIPDKGSSIPSSSFHTSVHHQSIHTPA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LGNYEEVKEFLSTKSHTHRLDASENRLGKPKYPLIPDKGSSIPSSSFHTSVHHQSIHTPA
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB9 SGPLSVGNISHNPKMAQPRTEPMPSLHAKSCGPPDSQHLTQDRLGQEGFGSSHHKKGDRR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SGPLSVGNISHNPKMAQPRTEPMPSLHAKSCGPPDSQHLTQDRLGQEGFGSSHHKKGDRR
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB9 ADGDHCASVTDSAPERELSPLISLPSPVPPLSPIHSNQQTLPRTQGSSKVHGSSNNSKGY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ADGDHCASVTDSAPERELSPLISLPSPVPPLSPIHSNQQTLPRTQGSSKVHGSSNNSKGY
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB9 CPAKSPKDLAVKVHDKETPQDSLVAPAQPPSQTFPPPSLPSKSVAMQQKPTAYVRPMDGQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 CPAKSPKDLAVKVHDKETPQDSLVAPAQPPSQTFPPPSLPSKSVAMQQKPTAYVRPMDGQ
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KB9 DQAPSESPELKPLPEDYRQQTFEKTDLKVPAKAKLTKLKMPSQSVEQTYSNEVHCVEEIL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DQAPSESPELKPLPEDYRQQTFEKTDLKVPAKAKLTKLKMPSQSVEQTYSNEVHCVEEIL
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KB9 KEMTHSWPPPLTAIHTPSTAEPSKFPFPTKDSQHVSSVTQNQKQYDTSSKTHSNSQQGTS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KEMTHSWPPPLTAIHTPSTAEPSKFPFPTKDSQHVSSVTQNQKQYDTSSKTHSNSQQGTS
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KB9 SMLEDDLQLSDSEDSDSEQTPEKPPSSSAPPSAPQSLPEPVASAHSSSAESESTSDSDSS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SMLEDDLQLSDSEDSDSEQTPEKPPSSSAPPSAPQSLPEPVASAHSSSAESESTSDSDSS
              430       440       450       460       470       480

              490       500       510       520       530       540
pF1KB9 SDSESESSSSDSEENEPLETPAPEPEPPTTNKWQLDNWLTKVSQPAAPPEGPRSTEPPRR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SDSESESSSSDSEENEPLETPAPEPEPPTTNKWQLDNWLTKVSQPAAPPEGPRSTEPPRR
              490       500       510       520       530       540

              550       560       570       580       590       600
pF1KB9 HPESKGSSDSATSQEHSESKDPPPKSSSKAPRAPPEAPHPGKRSCQKSPAQQEPPQRQTV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 HPESKGSSDSATSQEHSESKDPPPKSSSKAPRAPPEAPHPGKRSCQKSPAQQEPPQRQTV
              550       560       570       580       590       600

              610       620       630       640       650       660
pF1KB9 GTKQPKKPVKASARAGSRTSLQGEREPGLLPYGSRDQTSKDKPKVKTKGRPRAAASNEPK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GTKQPKKPVKASARAGSRTSLQGEREPGLLPYGSRDQTSKDKPKVKTKGRPRAAASNEPK
              610       620       630       640       650       660

              670       680       690       700       710       720
pF1KB9 PAVPPSSEKKKHKSSLPAPSKALSGPEPAKDNVEDRTPEHFALVPLTESQGPPHSGSGSR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PAVPPSSEKKKHKSSLPAPSKALSGPEPAKDNVEDRTPEHFALVPLTESQGPPHSGSGSR
              670       680       690       700       710       720

              730       740       750       760       770       780
pF1KB9 TSGCRQAVVVQEDSRKDRLPLPLRDTKLLSPLRDTPPPQSLMVKITLDLLSRIPQPPGKG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TSGCRQAVVVQEDSRKDRLPLPLRDTKLLSPLRDTPPPQSLMVKITLDLLSRIPQPPGKG
              730       740       750       760       770       780

              790       800       810       820       830       840
pF1KB9 SRQRKAEDKQPPAGKKHSSEKRSSDSSSKLAKKRKGEAERDCDNKKIRLEKEIKSQSSSS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SRQRKAEDKQPPAGKKHSSEKRSSDSSSKLAKKRKGEAERDCDNKKIRLEKEIKSQSSSS
              790       800       810       820       830       840

              850       860       870       880       890       900
pF1KB9 SSSHKESSKTKPSRPSSQSSKKEMLPPPPVSSSSQKPAKPALKRSRREADTCGQDPPKSA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SSSHKESSKTKPSRPSSQSSKKEMLPPPPVSSSSQKPAKPALKRSRREADTCGQDPPKSA
              850       860       870       880       890       900

              910       920       930       940       950       960
pF1KB9 SSTKSNHKDSSIPKQRRVEGKGSRSSSEHKGSSGDTANPFPVPSLPNGNSKPGKPQVKFD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SSTKSNHKDSSIPKQRRVEGKGSRSSSEHKGSSGDTANPFPVPSLPNGNSKPGKPQVKFD
              910       920       930       940       950       960

              970       980       990      1000      1010      1020
pF1KB9 KQQADLHMREAKKMKQKAELMTDRVGKAFKYLEAVLSFIECGIATESESQSSKSAYSVYS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KQQADLHMREAKKMKQKAELMTDRVGKAFKYLEAVLSFIECGIATESESQSSKSAYSVYS
              970       980       990      1000      1010      1020

             1030      1040      1050      1060      1070      1080
pF1KB9 ETVDLIKFIMSLKSFSDATAPTQEKIFAVLCMRCQSILNMAMFRCKKDIAIKYSRTLNKH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ETVDLIKFIMSLKSFSDATAPTQEKIFAVLCMRCQSILNMAMFRCKKDIAIKYSRTLNKH
             1030      1040      1050      1060      1070      1080

             1090      1100      1110      1120      1130      1140
pF1KB9 FESSSKVAQAPSPCIARSTGTPSPLSPMPSPASSVGSQSSAGSVGSSGVAATISTPVTIQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FESSSKVAQAPSPCIARSTGTPSPLSPMPSPASSVGSQSSAGSVGSSGVAATISTPVTIQ
             1090      1100      1110      1120      1130      1140

             1150      1160      1170      1180      1190      1200
pF1KB9 NMTSSYVTITSHVLTAFDLWEQAEALTRKNKEFFARLSTNVCTLALNSSLVDLVHYTRQG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NMTSSYVTITSHVLTAFDLWEQAEALTRKNKEFFARLSTNVCTLALNSSLVDLVHYTRQG
             1150      1160      1170      1180      1190      1200

             1210 
pF1KB9 FQQLQELTKTP
       :::::::::::
NP_001 FQQLQELTKTP
             1210 

>>NP_005926 (OMIM: 159557) AF4/FMR2 family member 1 isof  (1210 aa)
 initn: 7624 init1: 7338 opt: 8039  Z-score: 3259.6  bits: 615.2 E(85289): 8.1e-175
Smith-Waterman score: 8039; 99.9% identity (99.9% similar) in 1211 aa overlap (1-1211:1-1210)

               10        20        30        40        50        60
pF1KB9 MAAQSSLYNDDRNLLRIREKERRNQEAHQEKEAFPEKIPLFGEPYKTAKGDELSSRIQNM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 MAAQSSLYNDDRNLLRIREKERRNQEAHQEKEAFPEKIPLFGEPYKTAKGDELSSRIQNM
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB9 LGNYEEVKEFLSTKSHTHRLDASENRLGKPKYPLIPDKGSSIPSSSFHTSVHHQSIHTPA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 LGNYEEVKEFLSTKSHTHRLDASENRLGKPKYPLIPDKGSSIPSSSFHTSVHHQSIHTPA
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB9 SGPLSVGNISHNPKMAQPRTEPMPSLHAKSCGPPDSQHLTQDRLGQEGFGSSHHKKGDRR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 SGPLSVGNISHNPKMAQPRTEPMPSLHAKSCGPPDSQHLTQDRLGQEGFGSSHHKKGDRR
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB9 ADGDHCASVTDSAPERELSPLISLPSPVPPLSPIHSNQQTLPRTQGSSKVHGSSNNSKGY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 ADGDHCASVTDSAPERELSPLISLPSPVPPLSPIHSNQQTLPRTQGSSKVHGSSNNSKGY
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB9 CPAKSPKDLAVKVHDKETPQDSLVAPAQPPSQTFPPPSLPSKSVAMQQKPTAYVRPMDGQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 CPAKSPKDLAVKVHDKETPQDSLVAPAQPPSQTFPPPSLPSKSVAMQQKPTAYVRPMDGQ
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KB9 DQAPSESPELKPLPEDYRQQTFEKTDLKVPAKAKLTKLKMPSQSVEQTYSNEVHCVEEIL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 DQAPSESPELKPLPEDYRQQTFEKTDLKVPAKAKLTKLKMPSQSVEQTYSNEVHCVEEIL
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KB9 KEMTHSWPPPLTAIHTPSTAEPSKFPFPTKDSQHVSSVTQNQKQYDTSSKTHSNSQQGTS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 KEMTHSWPPPLTAIHTPSTAEPSKFPFPTKDSQHVSSVTQNQKQYDTSSKTHSNSQQGTS
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KB9 SMLEDDLQLSDSEDSDSEQTPEKPPSSSAPPSAPQSLPEPVASAHSSSAESESTSDSDSS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 SMLEDDLQLSDSEDSDSEQTPEKPPSSSAPPSAPQSLPEPVASAHSSSAESESTSDSDSS
              430       440       450       460       470       480

              490       500       510       520       530       540
pF1KB9 SDSESESSSSDSEENEPLETPAPEPEPPTTNKWQLDNWLTKVSQPAAPPEGPRSTEPPRR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 SDSESESSSSDSEENEPLETPAPEPEPPTTNKWQLDNWLTKVSQPAAPPEGPRSTEPPRR
              490       500       510       520       530       540

              550       560       570       580       590       600
pF1KB9 HPESKGSSDSATSQEHSESKDPPPKSSSKAPRAPPEAPHPGKRSCQKSPAQQEPPQRQTV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 HPESKGSSDSATSQEHSESKDPPPKSSSKAPRAPPEAPHPGKRSCQKSPAQQEPPQRQTV
              550       560       570       580       590       600

              610       620       630       640       650       660
pF1KB9 GTKQPKKPVKASARAGSRTSLQGEREPGLLPYGSRDQTSKDKPKVKTKGRPRAAASNEPK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 GTKQPKKPVKASARAGSRTSLQGEREPGLLPYGSRDQTSKDKPKVKTKGRPRAAASNEPK
              610       620       630       640       650       660

              670       680       690       700       710       720
pF1KB9 PAVPPSSEKKKHKSSLPAPSKALSGPEPAKDNVEDRTPEHFALVPLTESQGPPHSGSGSR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 PAVPPSSEKKKHKSSLPAPSKALSGPEPAKDNVEDRTPEHFALVPLTESQGPPHSGSGSR
              670       680       690       700       710       720

              730       740       750       760       770       780
pF1KB9 TSGCRQAVVVQEDSRKDRLPLPLRDTKLLSPLRDTPPPQSLMVKITLDLLSRIPQPPGKG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 TSGCRQAVVVQEDSRKDRLPLPLRDTKLLSPLRDTPPPQSLMVKITLDLLSRIPQPPGKG
              730       740       750       760       770       780

              790       800       810       820       830       840
pF1KB9 SRQRKAEDKQPPAGKKHSSEKRSSDSSSKLAKKRKGEAERDCDNKKIRLEKEIKSQSSSS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 SRQRKAEDKQPPAGKKHSSEKRSSDSSSKLAKKRKGEAERDCDNKKIRLEKEIKSQSSSS
              790       800       810       820       830       840

              850       860       870       880       890       900
pF1KB9 SSSHKESSKTKPSRPSSQSSKKEMLPPPPVSSSSQKPAKPALKRSRREADTCGQDPPKSA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 SSSHKESSKTKPSRPSSQSSKKEMLPPPPVSSSSQKPAKPALKRSRREADTCGQDPPKSA
              850       860       870       880       890       900

              910       920       930       940       950       960
pF1KB9 SSTKSNHKDSSIPKQRRVEGKGSRSSSEHKGSSGDTANPFPVPSLPNGNSKPGKPQVKFD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 SSTKSNHKDSSIPKQRRVEGKGSRSSSEHKGSSGDTANPFPVPSLPNGNSKPGKPQVKFD
              910       920       930       940       950       960

              970       980       990      1000      1010      1020
pF1KB9 KQQADLHMREAKKMKQKAELMTDRVGKAFKYLEAVLSFIECGIATESESQSSKSAYSVYS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 KQQADLHMREAKKMKQKAELMTDRVGKAFKYLEAVLSFIECGIATESESQSSKSAYSVYS
              970       980       990      1000      1010      1020

             1030      1040      1050      1060      1070      1080
pF1KB9 ETVDLIKFIMSLKSFSDATAPTQEKIFAVLCMRCQSILNMAMFRCKKDIAIKYSRTLNKH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 ETVDLIKFIMSLKSFSDATAPTQEKIFAVLCMRCQSILNMAMFRCKKDIAIKYSRTLNKH
             1030      1040      1050      1060      1070      1080

             1090      1100      1110      1120      1130      1140
pF1KB9 FESSSKVAQAPSPCIARSTGTPSPLSPMPSPASSVGSQSSAGSVGSSGVAATISTPVTIQ
       :::::::::::::::: :::::::::::::::::::::::::::::::::::::::::::
NP_005 FESSSKVAQAPSPCIA-STGTPSPLSPMPSPASSVGSQSSAGSVGSSGVAATISTPVTIQ
             1090       1100      1110      1120      1130         

             1150      1160      1170      1180      1190      1200
pF1KB9 NMTSSYVTITSHVLTAFDLWEQAEALTRKNKEFFARLSTNVCTLALNSSLVDLVHYTRQG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 NMTSSYVTITSHVLTAFDLWEQAEALTRKNKEFFARLSTNVCTLALNSSLVDLVHYTRQG
    1140      1150      1160      1170      1180      1190         

             1210 
pF1KB9 FQQLQELTKTP
       :::::::::::
NP_005 FQQLQELTKTP
    1200      1210

>>XP_005263068 (OMIM: 159557) PREDICTED: AF4/FMR2 family  (1216 aa)
 initn: 8029 init1: 8029 opt: 8030  Z-score: 3255.9  bits: 614.5 E(85289): 1.3e-174
Smith-Waterman score: 8030; 99.7% identity (99.8% similar) in 1211 aa overlap (1-1211:6-1216)

                    10        20        30        40        50     
pF1KB9      MAAQSSLYNDDRNLLRIREKERRNQEAHQEKEAFPEKIPLFGEPYKTAKGDELSS
            :  . ::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MPSNAMFLMHSLYNDDRNLLRIREKERRNQEAHQEKEAFPEKIPLFGEPYKTAKGDELSS
               10        20        30        40        50        60

          60        70        80        90       100       110     
pF1KB9 RIQNMLGNYEEVKEFLSTKSHTHRLDASENRLGKPKYPLIPDKGSSIPSSSFHTSVHHQS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 RIQNMLGNYEEVKEFLSTKSHTHRLDASENRLGKPKYPLIPDKGSSIPSSSFHTSVHHQS
               70        80        90       100       110       120

         120       130       140       150       160       170     
pF1KB9 IHTPASGPLSVGNISHNPKMAQPRTEPMPSLHAKSCGPPDSQHLTQDRLGQEGFGSSHHK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 IHTPASGPLSVGNISHNPKMAQPRTEPMPSLHAKSCGPPDSQHLTQDRLGQEGFGSSHHK
              130       140       150       160       170       180

         180       190       200       210       220       230     
pF1KB9 KGDRRADGDHCASVTDSAPERELSPLISLPSPVPPLSPIHSNQQTLPRTQGSSKVHGSSN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 KGDRRADGDHCASVTDSAPERELSPLISLPSPVPPLSPIHSNQQTLPRTQGSSKVHGSSN
              190       200       210       220       230       240

         240       250       260       270       280       290     
pF1KB9 NSKGYCPAKSPKDLAVKVHDKETPQDSLVAPAQPPSQTFPPPSLPSKSVAMQQKPTAYVR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 NSKGYCPAKSPKDLAVKVHDKETPQDSLVAPAQPPSQTFPPPSLPSKSVAMQQKPTAYVR
              250       260       270       280       290       300

         300       310       320       330       340       350     
pF1KB9 PMDGQDQAPSESPELKPLPEDYRQQTFEKTDLKVPAKAKLTKLKMPSQSVEQTYSNEVHC
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 PMDGQDQAPSESPELKPLPEDYRQQTFEKTDLKVPAKAKLTKLKMPSQSVEQTYSNEVHC
              310       320       330       340       350       360

         360       370       380       390       400       410     
pF1KB9 VEEILKEMTHSWPPPLTAIHTPSTAEPSKFPFPTKDSQHVSSVTQNQKQYDTSSKTHSNS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 VEEILKEMTHSWPPPLTAIHTPSTAEPSKFPFPTKDSQHVSSVTQNQKQYDTSSKTHSNS
              370       380       390       400       410       420

         420       430       440       450       460       470     
pF1KB9 QQGTSSMLEDDLQLSDSEDSDSEQTPEKPPSSSAPPSAPQSLPEPVASAHSSSAESESTS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 QQGTSSMLEDDLQLSDSEDSDSEQTPEKPPSSSAPPSAPQSLPEPVASAHSSSAESESTS
              430       440       450       460       470       480

         480       490       500       510       520       530     
pF1KB9 DSDSSSDSESESSSSDSEENEPLETPAPEPEPPTTNKWQLDNWLTKVSQPAAPPEGPRST
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 DSDSSSDSESESSSSDSEENEPLETPAPEPEPPTTNKWQLDNWLTKVSQPAAPPEGPRST
              490       500       510       520       530       540

         540       550       560       570       580       590     
pF1KB9 EPPRRHPESKGSSDSATSQEHSESKDPPPKSSSKAPRAPPEAPHPGKRSCQKSPAQQEPP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 EPPRRHPESKGSSDSATSQEHSESKDPPPKSSSKAPRAPPEAPHPGKRSCQKSPAQQEPP
              550       560       570       580       590       600

         600       610       620       630       640       650     
pF1KB9 QRQTVGTKQPKKPVKASARAGSRTSLQGEREPGLLPYGSRDQTSKDKPKVKTKGRPRAAA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 QRQTVGTKQPKKPVKASARAGSRTSLQGEREPGLLPYGSRDQTSKDKPKVKTKGRPRAAA
              610       620       630       640       650       660

         660       670       680       690       700       710     
pF1KB9 SNEPKPAVPPSSEKKKHKSSLPAPSKALSGPEPAKDNVEDRTPEHFALVPLTESQGPPHS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SNEPKPAVPPSSEKKKHKSSLPAPSKALSGPEPAKDNVEDRTPEHFALVPLTESQGPPHS
              670       680       690       700       710       720

         720       730       740       750       760       770     
pF1KB9 GSGSRTSGCRQAVVVQEDSRKDRLPLPLRDTKLLSPLRDTPPPQSLMVKITLDLLSRIPQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 GSGSRTSGCRQAVVVQEDSRKDRLPLPLRDTKLLSPLRDTPPPQSLMVKITLDLLSRIPQ
              730       740       750       760       770       780

         780       790       800       810       820       830     
pF1KB9 PPGKGSRQRKAEDKQPPAGKKHSSEKRSSDSSSKLAKKRKGEAERDCDNKKIRLEKEIKS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 PPGKGSRQRKAEDKQPPAGKKHSSEKRSSDSSSKLAKKRKGEAERDCDNKKIRLEKEIKS
              790       800       810       820       830       840

         840       850       860       870       880       890     
pF1KB9 QSSSSSSSHKESSKTKPSRPSSQSSKKEMLPPPPVSSSSQKPAKPALKRSRREADTCGQD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 QSSSSSSSHKESSKTKPSRPSSQSSKKEMLPPPPVSSSSQKPAKPALKRSRREADTCGQD
              850       860       870       880       890       900

         900       910       920       930       940       950     
pF1KB9 PPKSASSTKSNHKDSSIPKQRRVEGKGSRSSSEHKGSSGDTANPFPVPSLPNGNSKPGKP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 PPKSASSTKSNHKDSSIPKQRRVEGKGSRSSSEHKGSSGDTANPFPVPSLPNGNSKPGKP
              910       920       930       940       950       960

         960       970       980       990      1000      1010     
pF1KB9 QVKFDKQQADLHMREAKKMKQKAELMTDRVGKAFKYLEAVLSFIECGIATESESQSSKSA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 QVKFDKQQADLHMREAKKMKQKAELMTDRVGKAFKYLEAVLSFIECGIATESESQSSKSA
              970       980       990      1000      1010      1020

        1020      1030      1040      1050      1060      1070     
pF1KB9 YSVYSETVDLIKFIMSLKSFSDATAPTQEKIFAVLCMRCQSILNMAMFRCKKDIAIKYSR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 YSVYSETVDLIKFIMSLKSFSDATAPTQEKIFAVLCMRCQSILNMAMFRCKKDIAIKYSR
             1030      1040      1050      1060      1070      1080

        1080      1090      1100      1110      1120      1130     
pF1KB9 TLNKHFESSSKVAQAPSPCIARSTGTPSPLSPMPSPASSVGSQSSAGSVGSSGVAATIST
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 TLNKHFESSSKVAQAPSPCIARSTGTPSPLSPMPSPASSVGSQSSAGSVGSSGVAATIST
             1090      1100      1110      1120      1130      1140

        1140      1150      1160      1170      1180      1190     
pF1KB9 PVTIQNMTSSYVTITSHVLTAFDLWEQAEALTRKNKEFFARLSTNVCTLALNSSLVDLVH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 PVTIQNMTSSYVTITSHVLTAFDLWEQAEALTRKNKEFFARLSTNVCTLALNSSLVDLVH
             1150      1160      1170      1180      1190      1200

        1200      1210 
pF1KB9 YTRQGFQQLQELTKTP
       ::::::::::::::::
XP_005 YTRQGFQQLQELTKTP
             1210      

>>XP_011530275 (OMIM: 159557) PREDICTED: AF4/FMR2 family  (1218 aa)
 initn: 8030 init1: 8030 opt: 8030  Z-score: 3255.9  bits: 614.5 E(85289): 1.3e-174
Smith-Waterman score: 8030; 99.9% identity (100.0% similar) in 1207 aa overlap (5-1211:12-1218)

                      10        20        30        40        50   
pF1KB9        MAAQSSLYNDDRNLLRIREKERRNQEAHQEKEAFPEKIPLFGEPYKTAKGDEL
                  .::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MAFTERVNSSGNSLYNDDRNLLRIREKERRNQEAHQEKEAFPEKIPLFGEPYKTAKGDEL
               10        20        30        40        50        60

            60        70        80        90       100       110   
pF1KB9 SSRIQNMLGNYEEVKEFLSTKSHTHRLDASENRLGKPKYPLIPDKGSSIPSSSFHTSVHH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SSRIQNMLGNYEEVKEFLSTKSHTHRLDASENRLGKPKYPLIPDKGSSIPSSSFHTSVHH
               70        80        90       100       110       120

           120       130       140       150       160       170   
pF1KB9 QSIHTPASGPLSVGNISHNPKMAQPRTEPMPSLHAKSCGPPDSQHLTQDRLGQEGFGSSH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QSIHTPASGPLSVGNISHNPKMAQPRTEPMPSLHAKSCGPPDSQHLTQDRLGQEGFGSSH
              130       140       150       160       170       180

           180       190       200       210       220       230   
pF1KB9 HKKGDRRADGDHCASVTDSAPERELSPLISLPSPVPPLSPIHSNQQTLPRTQGSSKVHGS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 HKKGDRRADGDHCASVTDSAPERELSPLISLPSPVPPLSPIHSNQQTLPRTQGSSKVHGS
              190       200       210       220       230       240

           240       250       260       270       280       290   
pF1KB9 SNNSKGYCPAKSPKDLAVKVHDKETPQDSLVAPAQPPSQTFPPPSLPSKSVAMQQKPTAY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SNNSKGYCPAKSPKDLAVKVHDKETPQDSLVAPAQPPSQTFPPPSLPSKSVAMQQKPTAY
              250       260       270       280       290       300

           300       310       320       330       340       350   
pF1KB9 VRPMDGQDQAPSESPELKPLPEDYRQQTFEKTDLKVPAKAKLTKLKMPSQSVEQTYSNEV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VRPMDGQDQAPSESPELKPLPEDYRQQTFEKTDLKVPAKAKLTKLKMPSQSVEQTYSNEV
              310       320       330       340       350       360

           360       370       380       390       400       410   
pF1KB9 HCVEEILKEMTHSWPPPLTAIHTPSTAEPSKFPFPTKDSQHVSSVTQNQKQYDTSSKTHS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 HCVEEILKEMTHSWPPPLTAIHTPSTAEPSKFPFPTKDSQHVSSVTQNQKQYDTSSKTHS
              370       380       390       400       410       420

           420       430       440       450       460       470   
pF1KB9 NSQQGTSSMLEDDLQLSDSEDSDSEQTPEKPPSSSAPPSAPQSLPEPVASAHSSSAESES
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NSQQGTSSMLEDDLQLSDSEDSDSEQTPEKPPSSSAPPSAPQSLPEPVASAHSSSAESES
              430       440       450       460       470       480

           480       490       500       510       520       530   
pF1KB9 TSDSDSSSDSESESSSSDSEENEPLETPAPEPEPPTTNKWQLDNWLTKVSQPAAPPEGPR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TSDSDSSSDSESESSSSDSEENEPLETPAPEPEPPTTNKWQLDNWLTKVSQPAAPPEGPR
              490       500       510       520       530       540

           540       550       560       570       580       590   
pF1KB9 STEPPRRHPESKGSSDSATSQEHSESKDPPPKSSSKAPRAPPEAPHPGKRSCQKSPAQQE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 STEPPRRHPESKGSSDSATSQEHSESKDPPPKSSSKAPRAPPEAPHPGKRSCQKSPAQQE
              550       560       570       580       590       600

           600       610       620       630       640       650   
pF1KB9 PPQRQTVGTKQPKKPVKASARAGSRTSLQGEREPGLLPYGSRDQTSKDKPKVKTKGRPRA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PPQRQTVGTKQPKKPVKASARAGSRTSLQGEREPGLLPYGSRDQTSKDKPKVKTKGRPRA
              610       620       630       640       650       660

           660       670       680       690       700       710   
pF1KB9 AASNEPKPAVPPSSEKKKHKSSLPAPSKALSGPEPAKDNVEDRTPEHFALVPLTESQGPP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AASNEPKPAVPPSSEKKKHKSSLPAPSKALSGPEPAKDNVEDRTPEHFALVPLTESQGPP
              670       680       690       700       710       720

           720       730       740       750       760       770   
pF1KB9 HSGSGSRTSGCRQAVVVQEDSRKDRLPLPLRDTKLLSPLRDTPPPQSLMVKITLDLLSRI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 HSGSGSRTSGCRQAVVVQEDSRKDRLPLPLRDTKLLSPLRDTPPPQSLMVKITLDLLSRI
              730       740       750       760       770       780

           780       790       800       810       820       830   
pF1KB9 PQPPGKGSRQRKAEDKQPPAGKKHSSEKRSSDSSSKLAKKRKGEAERDCDNKKIRLEKEI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PQPPGKGSRQRKAEDKQPPAGKKHSSEKRSSDSSSKLAKKRKGEAERDCDNKKIRLEKEI
              790       800       810       820       830       840

           840       850       860       870       880       890   
pF1KB9 KSQSSSSSSSHKESSKTKPSRPSSQSSKKEMLPPPPVSSSSQKPAKPALKRSRREADTCG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KSQSSSSSSSHKESSKTKPSRPSSQSSKKEMLPPPPVSSSSQKPAKPALKRSRREADTCG
              850       860       870       880       890       900

           900       910       920       930       940       950   
pF1KB9 QDPPKSASSTKSNHKDSSIPKQRRVEGKGSRSSSEHKGSSGDTANPFPVPSLPNGNSKPG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QDPPKSASSTKSNHKDSSIPKQRRVEGKGSRSSSEHKGSSGDTANPFPVPSLPNGNSKPG
              910       920       930       940       950       960

           960       970       980       990      1000      1010   
pF1KB9 KPQVKFDKQQADLHMREAKKMKQKAELMTDRVGKAFKYLEAVLSFIECGIATESESQSSK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KPQVKFDKQQADLHMREAKKMKQKAELMTDRVGKAFKYLEAVLSFIECGIATESESQSSK
              970       980       990      1000      1010      1020

          1020      1030      1040      1050      1060      1070   
pF1KB9 SAYSVYSETVDLIKFIMSLKSFSDATAPTQEKIFAVLCMRCQSILNMAMFRCKKDIAIKY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SAYSVYSETVDLIKFIMSLKSFSDATAPTQEKIFAVLCMRCQSILNMAMFRCKKDIAIKY
             1030      1040      1050      1060      1070      1080

          1080      1090      1100      1110      1120      1130   
pF1KB9 SRTLNKHFESSSKVAQAPSPCIARSTGTPSPLSPMPSPASSVGSQSSAGSVGSSGVAATI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SRTLNKHFESSSKVAQAPSPCIARSTGTPSPLSPMPSPASSVGSQSSAGSVGSSGVAATI
             1090      1100      1110      1120      1130      1140

          1140      1150      1160      1170      1180      1190   
pF1KB9 STPVTIQNMTSSYVTITSHVLTAFDLWEQAEALTRKNKEFFARLSTNVCTLALNSSLVDL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 STPVTIQNMTSSYVTITSHVLTAFDLWEQAEALTRKNKEFFARLSTNVCTLALNSSLVDL
             1150      1160      1170      1180      1190      1200

          1200      1210 
pF1KB9 VHYTRQGFQQLQELTKTP
       ::::::::::::::::::
XP_011 VHYTRQGFQQLQELTKTP
             1210        

>>NP_001160165 (OMIM: 159557) AF4/FMR2 family member 1 i  (1218 aa)
 initn: 8030 init1: 8030 opt: 8030  Z-score: 3255.9  bits: 614.5 E(85289): 1.3e-174
Smith-Waterman score: 8030; 99.9% identity (100.0% similar) in 1207 aa overlap (5-1211:12-1218)

                      10        20        30        40        50   
pF1KB9        MAAQSSLYNDDRNLLRIREKERRNQEAHQEKEAFPEKIPLFGEPYKTAKGDEL
                  .::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MAFTERVNSSGNSLYNDDRNLLRIREKERRNQEAHQEKEAFPEKIPLFGEPYKTAKGDEL
               10        20        30        40        50        60

            60        70        80        90       100       110   
pF1KB9 SSRIQNMLGNYEEVKEFLSTKSHTHRLDASENRLGKPKYPLIPDKGSSIPSSSFHTSVHH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SSRIQNMLGNYEEVKEFLSTKSHTHRLDASENRLGKPKYPLIPDKGSSIPSSSFHTSVHH
               70        80        90       100       110       120

           120       130       140       150       160       170   
pF1KB9 QSIHTPASGPLSVGNISHNPKMAQPRTEPMPSLHAKSCGPPDSQHLTQDRLGQEGFGSSH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QSIHTPASGPLSVGNISHNPKMAQPRTEPMPSLHAKSCGPPDSQHLTQDRLGQEGFGSSH
              130       140       150       160       170       180

           180       190       200       210       220       230   
pF1KB9 HKKGDRRADGDHCASVTDSAPERELSPLISLPSPVPPLSPIHSNQQTLPRTQGSSKVHGS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 HKKGDRRADGDHCASVTDSAPERELSPLISLPSPVPPLSPIHSNQQTLPRTQGSSKVHGS
              190       200       210       220       230       240

           240       250       260       270       280       290   
pF1KB9 SNNSKGYCPAKSPKDLAVKVHDKETPQDSLVAPAQPPSQTFPPPSLPSKSVAMQQKPTAY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SNNSKGYCPAKSPKDLAVKVHDKETPQDSLVAPAQPPSQTFPPPSLPSKSVAMQQKPTAY
              250       260       270       280       290       300

           300       310       320       330       340       350   
pF1KB9 VRPMDGQDQAPSESPELKPLPEDYRQQTFEKTDLKVPAKAKLTKLKMPSQSVEQTYSNEV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VRPMDGQDQAPSESPELKPLPEDYRQQTFEKTDLKVPAKAKLTKLKMPSQSVEQTYSNEV
              310       320       330       340       350       360

           360       370       380       390       400       410   
pF1KB9 HCVEEILKEMTHSWPPPLTAIHTPSTAEPSKFPFPTKDSQHVSSVTQNQKQYDTSSKTHS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 HCVEEILKEMTHSWPPPLTAIHTPSTAEPSKFPFPTKDSQHVSSVTQNQKQYDTSSKTHS
              370       380       390       400       410       420

           420       430       440       450       460       470   
pF1KB9 NSQQGTSSMLEDDLQLSDSEDSDSEQTPEKPPSSSAPPSAPQSLPEPVASAHSSSAESES
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NSQQGTSSMLEDDLQLSDSEDSDSEQTPEKPPSSSAPPSAPQSLPEPVASAHSSSAESES
              430       440       450       460       470       480

           480       490       500       510       520       530   
pF1KB9 TSDSDSSSDSESESSSSDSEENEPLETPAPEPEPPTTNKWQLDNWLTKVSQPAAPPEGPR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TSDSDSSSDSESESSSSDSEENEPLETPAPEPEPPTTNKWQLDNWLTKVSQPAAPPEGPR
              490       500       510       520       530       540

           540       550       560       570       580       590   
pF1KB9 STEPPRRHPESKGSSDSATSQEHSESKDPPPKSSSKAPRAPPEAPHPGKRSCQKSPAQQE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 STEPPRRHPESKGSSDSATSQEHSESKDPPPKSSSKAPRAPPEAPHPGKRSCQKSPAQQE
              550       560       570       580       590       600

           600       610       620       630       640       650   
pF1KB9 PPQRQTVGTKQPKKPVKASARAGSRTSLQGEREPGLLPYGSRDQTSKDKPKVKTKGRPRA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PPQRQTVGTKQPKKPVKASARAGSRTSLQGEREPGLLPYGSRDQTSKDKPKVKTKGRPRA
              610       620       630       640       650       660

           660       670       680       690       700       710   
pF1KB9 AASNEPKPAVPPSSEKKKHKSSLPAPSKALSGPEPAKDNVEDRTPEHFALVPLTESQGPP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AASNEPKPAVPPSSEKKKHKSSLPAPSKALSGPEPAKDNVEDRTPEHFALVPLTESQGPP
              670       680       690       700       710       720

           720       730       740       750       760       770   
pF1KB9 HSGSGSRTSGCRQAVVVQEDSRKDRLPLPLRDTKLLSPLRDTPPPQSLMVKITLDLLSRI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 HSGSGSRTSGCRQAVVVQEDSRKDRLPLPLRDTKLLSPLRDTPPPQSLMVKITLDLLSRI
              730       740       750       760       770       780

           780       790       800       810       820       830   
pF1KB9 PQPPGKGSRQRKAEDKQPPAGKKHSSEKRSSDSSSKLAKKRKGEAERDCDNKKIRLEKEI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PQPPGKGSRQRKAEDKQPPAGKKHSSEKRSSDSSSKLAKKRKGEAERDCDNKKIRLEKEI
              790       800       810       820       830       840

           840       850       860       870       880       890   
pF1KB9 KSQSSSSSSSHKESSKTKPSRPSSQSSKKEMLPPPPVSSSSQKPAKPALKRSRREADTCG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KSQSSSSSSSHKESSKTKPSRPSSQSSKKEMLPPPPVSSSSQKPAKPALKRSRREADTCG
              850       860       870       880       890       900

           900       910       920       930       940       950   
pF1KB9 QDPPKSASSTKSNHKDSSIPKQRRVEGKGSRSSSEHKGSSGDTANPFPVPSLPNGNSKPG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QDPPKSASSTKSNHKDSSIPKQRRVEGKGSRSSSEHKGSSGDTANPFPVPSLPNGNSKPG
              910       920       930       940       950       960

           960       970       980       990      1000      1010   
pF1KB9 KPQVKFDKQQADLHMREAKKMKQKAELMTDRVGKAFKYLEAVLSFIECGIATESESQSSK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KPQVKFDKQQADLHMREAKKMKQKAELMTDRVGKAFKYLEAVLSFIECGIATESESQSSK
              970       980       990      1000      1010      1020

          1020      1030      1040      1050      1060      1070   
pF1KB9 SAYSVYSETVDLIKFIMSLKSFSDATAPTQEKIFAVLCMRCQSILNMAMFRCKKDIAIKY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SAYSVYSETVDLIKFIMSLKSFSDATAPTQEKIFAVLCMRCQSILNMAMFRCKKDIAIKY
             1030      1040      1050      1060      1070      1080

          1080      1090      1100      1110      1120      1130   
pF1KB9 SRTLNKHFESSSKVAQAPSPCIARSTGTPSPLSPMPSPASSVGSQSSAGSVGSSGVAATI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SRTLNKHFESSSKVAQAPSPCIARSTGTPSPLSPMPSPASSVGSQSSAGSVGSSGVAATI
             1090      1100      1110      1120      1130      1140

          1140      1150      1160      1170      1180      1190   
pF1KB9 STPVTIQNMTSSYVTITSHVLTAFDLWEQAEALTRKNKEFFARLSTNVCTLALNSSLVDL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 STPVTIQNMTSSYVTITSHVLTAFDLWEQAEALTRKNKEFFARLSTNVCTLALNSSLVDL
             1150      1160      1170      1180      1190      1200

          1200      1210 
pF1KB9 VHYTRQGFQQLQELTKTP
       ::::::::::::::::::
NP_001 VHYTRQGFQQLQELTKTP
             1210        

>>XP_005263064 (OMIM: 159557) PREDICTED: AF4/FMR2 family  (1218 aa)
 initn: 8030 init1: 8030 opt: 8030  Z-score: 3255.9  bits: 614.5 E(85289): 1.3e-174
Smith-Waterman score: 8030; 99.9% identity (100.0% similar) in 1207 aa overlap (5-1211:12-1218)

                      10        20        30        40        50   
pF1KB9        MAAQSSLYNDDRNLLRIREKERRNQEAHQEKEAFPEKIPLFGEPYKTAKGDEL
                  .::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MAFTERVNSSGNSLYNDDRNLLRIREKERRNQEAHQEKEAFPEKIPLFGEPYKTAKGDEL
               10        20        30        40        50        60

            60        70        80        90       100       110   
pF1KB9 SSRIQNMLGNYEEVKEFLSTKSHTHRLDASENRLGKPKYPLIPDKGSSIPSSSFHTSVHH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SSRIQNMLGNYEEVKEFLSTKSHTHRLDASENRLGKPKYPLIPDKGSSIPSSSFHTSVHH
               70        80        90       100       110       120

           120       130       140       150       160       170   
pF1KB9 QSIHTPASGPLSVGNISHNPKMAQPRTEPMPSLHAKSCGPPDSQHLTQDRLGQEGFGSSH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 QSIHTPASGPLSVGNISHNPKMAQPRTEPMPSLHAKSCGPPDSQHLTQDRLGQEGFGSSH
              130       140       150       160       170       180

           180       190       200       210       220       230   
pF1KB9 HKKGDRRADGDHCASVTDSAPERELSPLISLPSPVPPLSPIHSNQQTLPRTQGSSKVHGS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 HKKGDRRADGDHCASVTDSAPERELSPLISLPSPVPPLSPIHSNQQTLPRTQGSSKVHGS
              190       200       210       220       230       240

           240       250       260       270       280       290   
pF1KB9 SNNSKGYCPAKSPKDLAVKVHDKETPQDSLVAPAQPPSQTFPPPSLPSKSVAMQQKPTAY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SNNSKGYCPAKSPKDLAVKVHDKETPQDSLVAPAQPPSQTFPPPSLPSKSVAMQQKPTAY
              250       260       270       280       290       300

           300       310       320       330       340       350   
pF1KB9 VRPMDGQDQAPSESPELKPLPEDYRQQTFEKTDLKVPAKAKLTKLKMPSQSVEQTYSNEV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 VRPMDGQDQAPSESPELKPLPEDYRQQTFEKTDLKVPAKAKLTKLKMPSQSVEQTYSNEV
              310       320       330       340       350       360

           360       370       380       390       400       410   
pF1KB9 HCVEEILKEMTHSWPPPLTAIHTPSTAEPSKFPFPTKDSQHVSSVTQNQKQYDTSSKTHS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 HCVEEILKEMTHSWPPPLTAIHTPSTAEPSKFPFPTKDSQHVSSVTQNQKQYDTSSKTHS
              370       380       390       400       410       420

           420       430       440       450       460       470   
pF1KB9 NSQQGTSSMLEDDLQLSDSEDSDSEQTPEKPPSSSAPPSAPQSLPEPVASAHSSSAESES
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 NSQQGTSSMLEDDLQLSDSEDSDSEQTPEKPPSSSAPPSAPQSLPEPVASAHSSSAESES
              430       440       450       460       470       480

           480       490       500       510       520       530   
pF1KB9 TSDSDSSSDSESESSSSDSEENEPLETPAPEPEPPTTNKWQLDNWLTKVSQPAAPPEGPR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 TSDSDSSSDSESESSSSDSEENEPLETPAPEPEPPTTNKWQLDNWLTKVSQPAAPPEGPR
              490       500       510       520       530       540

           540       550       560       570       580       590   
pF1KB9 STEPPRRHPESKGSSDSATSQEHSESKDPPPKSSSKAPRAPPEAPHPGKRSCQKSPAQQE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 STEPPRRHPESKGSSDSATSQEHSESKDPPPKSSSKAPRAPPEAPHPGKRSCQKSPAQQE
              550       560       570       580       590       600

           600       610       620       630       640       650   
pF1KB9 PPQRQTVGTKQPKKPVKASARAGSRTSLQGEREPGLLPYGSRDQTSKDKPKVKTKGRPRA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 PPQRQTVGTKQPKKPVKASARAGSRTSLQGEREPGLLPYGSRDQTSKDKPKVKTKGRPRA
              610       620       630       640       650       660

           660       670       680       690       700       710   
pF1KB9 AASNEPKPAVPPSSEKKKHKSSLPAPSKALSGPEPAKDNVEDRTPEHFALVPLTESQGPP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 AASNEPKPAVPPSSEKKKHKSSLPAPSKALSGPEPAKDNVEDRTPEHFALVPLTESQGPP
              670       680       690       700       710       720

           720       730       740       750       760       770   
pF1KB9 HSGSGSRTSGCRQAVVVQEDSRKDRLPLPLRDTKLLSPLRDTPPPQSLMVKITLDLLSRI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 HSGSGSRTSGCRQAVVVQEDSRKDRLPLPLRDTKLLSPLRDTPPPQSLMVKITLDLLSRI
              730       740       750       760       770       780

           780       790       800       810       820       830   
pF1KB9 PQPPGKGSRQRKAEDKQPPAGKKHSSEKRSSDSSSKLAKKRKGEAERDCDNKKIRLEKEI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 PQPPGKGSRQRKAEDKQPPAGKKHSSEKRSSDSSSKLAKKRKGEAERDCDNKKIRLEKEI
              790       800       810       820       830       840

           840       850       860       870       880       890   
pF1KB9 KSQSSSSSSSHKESSKTKPSRPSSQSSKKEMLPPPPVSSSSQKPAKPALKRSRREADTCG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 KSQSSSSSSSHKESSKTKPSRPSSQSSKKEMLPPPPVSSSSQKPAKPALKRSRREADTCG
              850       860       870       880       890       900

           900       910       920       930       940       950   
pF1KB9 QDPPKSASSTKSNHKDSSIPKQRRVEGKGSRSSSEHKGSSGDTANPFPVPSLPNGNSKPG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 QDPPKSASSTKSNHKDSSIPKQRRVEGKGSRSSSEHKGSSGDTANPFPVPSLPNGNSKPG
              910       920       930       940       950       960

           960       970       980       990      1000      1010   
pF1KB9 KPQVKFDKQQADLHMREAKKMKQKAELMTDRVGKAFKYLEAVLSFIECGIATESESQSSK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 KPQVKFDKQQADLHMREAKKMKQKAELMTDRVGKAFKYLEAVLSFIECGIATESESQSSK
              970       980       990      1000      1010      1020

          1020      1030      1040      1050      1060      1070   
pF1KB9 SAYSVYSETVDLIKFIMSLKSFSDATAPTQEKIFAVLCMRCQSILNMAMFRCKKDIAIKY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SAYSVYSETVDLIKFIMSLKSFSDATAPTQEKIFAVLCMRCQSILNMAMFRCKKDIAIKY
             1030      1040      1050      1060      1070      1080

          1080      1090      1100      1110      1120      1130   
pF1KB9 SRTLNKHFESSSKVAQAPSPCIARSTGTPSPLSPMPSPASSVGSQSSAGSVGSSGVAATI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SRTLNKHFESSSKVAQAPSPCIARSTGTPSPLSPMPSPASSVGSQSSAGSVGSSGVAATI
             1090      1100      1110      1120      1130      1140

          1140      1150      1160      1170      1180      1190   
pF1KB9 STPVTIQNMTSSYVTITSHVLTAFDLWEQAEALTRKNKEFFARLSTNVCTLALNSSLVDL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 STPVTIQNMTSSYVTITSHVLTAFDLWEQAEALTRKNKEFFARLSTNVCTLALNSSLVDL
             1150      1160      1170      1180      1190      1200

          1200      1210 
pF1KB9 VHYTRQGFQQLQELTKTP
       ::::::::::::::::::
XP_005 VHYTRQGFQQLQELTKTP
             1210        

>>XP_005263066 (OMIM: 159557) PREDICTED: AF4/FMR2 family  (1217 aa)
 initn: 5704 init1: 5704 opt: 8011  Z-score: 3248.2  bits: 613.1 E(85289): 3.4e-174
Smith-Waterman score: 8011; 99.8% identity (99.9% similar) in 1207 aa overlap (5-1211:12-1217)

                      10        20        30        40        50   
pF1KB9        MAAQSSLYNDDRNLLRIREKERRNQEAHQEKEAFPEKIPLFGEPYKTAKGDEL
                  .::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MAFTERVNSSGNSLYNDDRNLLRIREKERRNQEAHQEKEAFPEKIPLFGEPYKTAKGDEL
               10        20        30        40        50        60

            60        70        80        90       100       110   
pF1KB9 SSRIQNMLGNYEEVKEFLSTKSHTHRLDASENRLGKPKYPLIPDKGSSIPSSSFHTSVHH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SSRIQNMLGNYEEVKEFLSTKSHTHRLDASENRLGKPKYPLIPDKGSSIPSSSFHTSVHH
               70        80        90       100       110       120

           120       130       140       150       160       170   
pF1KB9 QSIHTPASGPLSVGNISHNPKMAQPRTEPMPSLHAKSCGPPDSQHLTQDRLGQEGFGSSH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 QSIHTPASGPLSVGNISHNPKMAQPRTEPMPSLHAKSCGPPDSQHLTQDRLGQEGFGSSH
              130       140       150       160       170       180

           180       190       200       210       220       230   
pF1KB9 HKKGDRRADGDHCASVTDSAPERELSPLISLPSPVPPLSPIHSNQQTLPRTQGSSKVHGS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 HKKGDRRADGDHCASVTDSAPERELSPLISLPSPVPPLSPIHSNQQTLPRTQGSSKVHGS
              190       200       210       220       230       240

           240       250       260       270       280       290   
pF1KB9 SNNSKGYCPAKSPKDLAVKVHDKETPQDSLVAPAQPPSQTFPPPSLPSKSVAMQQKPTAY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SNNSKGYCPAKSPKDLAVKVHDKETPQDSLVAPAQPPSQTFPPPSLPSKSVAMQQKPTAY
              250       260       270       280       290       300

           300       310       320       330       340       350   
pF1KB9 VRPMDGQDQAPSESPELKPLPEDYRQQTFEKTDLKVPAKAKLTKLKMPSQSVEQTYSNEV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::: ::::::
XP_005 VRPMDGQDQAPSESPELKPLPEDYRQQTFEKTDLKVPAKAKLTKLKMPSQSVE-TYSNEV
              310       320       330       340       350          

           360       370       380       390       400       410   
pF1KB9 HCVEEILKEMTHSWPPPLTAIHTPSTAEPSKFPFPTKDSQHVSSVTQNQKQYDTSSKTHS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 HCVEEILKEMTHSWPPPLTAIHTPSTAEPSKFPFPTKDSQHVSSVTQNQKQYDTSSKTHS
     360       370       380       390       400       410         

           420       430       440       450       460       470   
pF1KB9 NSQQGTSSMLEDDLQLSDSEDSDSEQTPEKPPSSSAPPSAPQSLPEPVASAHSSSAESES
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 NSQQGTSSMLEDDLQLSDSEDSDSEQTPEKPPSSSAPPSAPQSLPEPVASAHSSSAESES
     420       430       440       450       460       470         

           480       490       500       510       520       530   
pF1KB9 TSDSDSSSDSESESSSSDSEENEPLETPAPEPEPPTTNKWQLDNWLTKVSQPAAPPEGPR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 TSDSDSSSDSESESSSSDSEENEPLETPAPEPEPPTTNKWQLDNWLTKVSQPAAPPEGPR
     480       490       500       510       520       530         

           540       550       560       570       580       590   
pF1KB9 STEPPRRHPESKGSSDSATSQEHSESKDPPPKSSSKAPRAPPEAPHPGKRSCQKSPAQQE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 STEPPRRHPESKGSSDSATSQEHSESKDPPPKSSSKAPRAPPEAPHPGKRSCQKSPAQQE
     540       550       560       570       580       590         

           600       610       620       630       640       650   
pF1KB9 PPQRQTVGTKQPKKPVKASARAGSRTSLQGEREPGLLPYGSRDQTSKDKPKVKTKGRPRA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 PPQRQTVGTKQPKKPVKASARAGSRTSLQGEREPGLLPYGSRDQTSKDKPKVKTKGRPRA
     600       610       620       630       640       650         

           660       670       680       690       700       710   
pF1KB9 AASNEPKPAVPPSSEKKKHKSSLPAPSKALSGPEPAKDNVEDRTPEHFALVPLTESQGPP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 AASNEPKPAVPPSSEKKKHKSSLPAPSKALSGPEPAKDNVEDRTPEHFALVPLTESQGPP
     660       670       680       690       700       710         

           720       730       740       750       760       770   
pF1KB9 HSGSGSRTSGCRQAVVVQEDSRKDRLPLPLRDTKLLSPLRDTPPPQSLMVKITLDLLSRI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 HSGSGSRTSGCRQAVVVQEDSRKDRLPLPLRDTKLLSPLRDTPPPQSLMVKITLDLLSRI
     720       730       740       750       760       770         

           780       790       800       810       820       830   
pF1KB9 PQPPGKGSRQRKAEDKQPPAGKKHSSEKRSSDSSSKLAKKRKGEAERDCDNKKIRLEKEI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 PQPPGKGSRQRKAEDKQPPAGKKHSSEKRSSDSSSKLAKKRKGEAERDCDNKKIRLEKEI
     780       790       800       810       820       830         

           840       850       860       870       880       890   
pF1KB9 KSQSSSSSSSHKESSKTKPSRPSSQSSKKEMLPPPPVSSSSQKPAKPALKRSRREADTCG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 KSQSSSSSSSHKESSKTKPSRPSSQSSKKEMLPPPPVSSSSQKPAKPALKRSRREADTCG
     840       850       860       870       880       890         

           900       910       920       930       940       950   
pF1KB9 QDPPKSASSTKSNHKDSSIPKQRRVEGKGSRSSSEHKGSSGDTANPFPVPSLPNGNSKPG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 QDPPKSASSTKSNHKDSSIPKQRRVEGKGSRSSSEHKGSSGDTANPFPVPSLPNGNSKPG
     900       910       920       930       940       950         

           960       970       980       990      1000      1010   
pF1KB9 KPQVKFDKQQADLHMREAKKMKQKAELMTDRVGKAFKYLEAVLSFIECGIATESESQSSK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 KPQVKFDKQQADLHMREAKKMKQKAELMTDRVGKAFKYLEAVLSFIECGIATESESQSSK
     960       970       980       990      1000      1010         

          1020      1030      1040      1050      1060      1070   
pF1KB9 SAYSVYSETVDLIKFIMSLKSFSDATAPTQEKIFAVLCMRCQSILNMAMFRCKKDIAIKY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SAYSVYSETVDLIKFIMSLKSFSDATAPTQEKIFAVLCMRCQSILNMAMFRCKKDIAIKY
    1020      1030      1040      1050      1060      1070         

          1080      1090      1100      1110      1120      1130   
pF1KB9 SRTLNKHFESSSKVAQAPSPCIARSTGTPSPLSPMPSPASSVGSQSSAGSVGSSGVAATI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SRTLNKHFESSSKVAQAPSPCIARSTGTPSPLSPMPSPASSVGSQSSAGSVGSSGVAATI
    1080      1090      1100      1110      1120      1130         

          1140      1150      1160      1170      1180      1190   
pF1KB9 STPVTIQNMTSSYVTITSHVLTAFDLWEQAEALTRKNKEFFARLSTNVCTLALNSSLVDL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 STPVTIQNMTSSYVTITSHVLTAFDLWEQAEALTRKNKEFFARLSTNVCTLALNSSLVDL
    1140      1150      1160      1170      1180      1190         

          1200      1210 
pF1KB9 VHYTRQGFQQLQELTKTP
       ::::::::::::::::::
XP_005 VHYTRQGFQQLQELTKTP
    1200      1210       

>>XP_005263070 (OMIM: 159557) PREDICTED: AF4/FMR2 family  (1057 aa)
 initn: 6994 init1: 6994 opt: 6994  Z-score: 2839.3  bits: 537.2 E(85289): 2.1e-151
Smith-Waterman score: 6994; 99.9% identity (100.0% similar) in 1046 aa overlap (5-1050:12-1057)

                      10        20        30        40        50   
pF1KB9        MAAQSSLYNDDRNLLRIREKERRNQEAHQEKEAFPEKIPLFGEPYKTAKGDEL
                  .::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MAFTERVNSSGNSLYNDDRNLLRIREKERRNQEAHQEKEAFPEKIPLFGEPYKTAKGDEL
               10        20        30        40        50        60

            60        70        80        90       100       110   
pF1KB9 SSRIQNMLGNYEEVKEFLSTKSHTHRLDASENRLGKPKYPLIPDKGSSIPSSSFHTSVHH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SSRIQNMLGNYEEVKEFLSTKSHTHRLDASENRLGKPKYPLIPDKGSSIPSSSFHTSVHH
               70        80        90       100       110       120

           120       130       140       150       160       170   
pF1KB9 QSIHTPASGPLSVGNISHNPKMAQPRTEPMPSLHAKSCGPPDSQHLTQDRLGQEGFGSSH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 QSIHTPASGPLSVGNISHNPKMAQPRTEPMPSLHAKSCGPPDSQHLTQDRLGQEGFGSSH
              130       140       150       160       170       180

           180       190       200       210       220       230   
pF1KB9 HKKGDRRADGDHCASVTDSAPERELSPLISLPSPVPPLSPIHSNQQTLPRTQGSSKVHGS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 HKKGDRRADGDHCASVTDSAPERELSPLISLPSPVPPLSPIHSNQQTLPRTQGSSKVHGS
              190       200       210       220       230       240

           240       250       260       270       280       290   
pF1KB9 SNNSKGYCPAKSPKDLAVKVHDKETPQDSLVAPAQPPSQTFPPPSLPSKSVAMQQKPTAY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SNNSKGYCPAKSPKDLAVKVHDKETPQDSLVAPAQPPSQTFPPPSLPSKSVAMQQKPTAY
              250       260       270       280       290       300

           300       310       320       330       340       350   
pF1KB9 VRPMDGQDQAPSESPELKPLPEDYRQQTFEKTDLKVPAKAKLTKLKMPSQSVEQTYSNEV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 VRPMDGQDQAPSESPELKPLPEDYRQQTFEKTDLKVPAKAKLTKLKMPSQSVEQTYSNEV
              310       320       330       340       350       360

           360       370       380       390       400       410   
pF1KB9 HCVEEILKEMTHSWPPPLTAIHTPSTAEPSKFPFPTKDSQHVSSVTQNQKQYDTSSKTHS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 HCVEEILKEMTHSWPPPLTAIHTPSTAEPSKFPFPTKDSQHVSSVTQNQKQYDTSSKTHS
              370       380       390       400       410       420

           420       430       440       450       460       470   
pF1KB9 NSQQGTSSMLEDDLQLSDSEDSDSEQTPEKPPSSSAPPSAPQSLPEPVASAHSSSAESES
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 NSQQGTSSMLEDDLQLSDSEDSDSEQTPEKPPSSSAPPSAPQSLPEPVASAHSSSAESES
              430       440       450       460       470       480

           480       490       500       510       520       530   
pF1KB9 TSDSDSSSDSESESSSSDSEENEPLETPAPEPEPPTTNKWQLDNWLTKVSQPAAPPEGPR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 TSDSDSSSDSESESSSSDSEENEPLETPAPEPEPPTTNKWQLDNWLTKVSQPAAPPEGPR
              490       500       510       520       530       540

           540       550       560       570       580       590   
pF1KB9 STEPPRRHPESKGSSDSATSQEHSESKDPPPKSSSKAPRAPPEAPHPGKRSCQKSPAQQE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 STEPPRRHPESKGSSDSATSQEHSESKDPPPKSSSKAPRAPPEAPHPGKRSCQKSPAQQE
              550       560       570       580       590       600

           600       610       620       630       640       650   
pF1KB9 PPQRQTVGTKQPKKPVKASARAGSRTSLQGEREPGLLPYGSRDQTSKDKPKVKTKGRPRA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 PPQRQTVGTKQPKKPVKASARAGSRTSLQGEREPGLLPYGSRDQTSKDKPKVKTKGRPRA
              610       620       630       640       650       660

           660       670       680       690       700       710   
pF1KB9 AASNEPKPAVPPSSEKKKHKSSLPAPSKALSGPEPAKDNVEDRTPEHFALVPLTESQGPP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 AASNEPKPAVPPSSEKKKHKSSLPAPSKALSGPEPAKDNVEDRTPEHFALVPLTESQGPP
              670       680       690       700       710       720

           720       730       740       750       760       770   
pF1KB9 HSGSGSRTSGCRQAVVVQEDSRKDRLPLPLRDTKLLSPLRDTPPPQSLMVKITLDLLSRI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 HSGSGSRTSGCRQAVVVQEDSRKDRLPLPLRDTKLLSPLRDTPPPQSLMVKITLDLLSRI
              730       740       750       760       770       780

           780       790       800       810       820       830   
pF1KB9 PQPPGKGSRQRKAEDKQPPAGKKHSSEKRSSDSSSKLAKKRKGEAERDCDNKKIRLEKEI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 PQPPGKGSRQRKAEDKQPPAGKKHSSEKRSSDSSSKLAKKRKGEAERDCDNKKIRLEKEI
              790       800       810       820       830       840

           840       850       860       870       880       890   
pF1KB9 KSQSSSSSSSHKESSKTKPSRPSSQSSKKEMLPPPPVSSSSQKPAKPALKRSRREADTCG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 KSQSSSSSSSHKESSKTKPSRPSSQSSKKEMLPPPPVSSSSQKPAKPALKRSRREADTCG
              850       860       870       880       890       900

           900       910       920       930       940       950   
pF1KB9 QDPPKSASSTKSNHKDSSIPKQRRVEGKGSRSSSEHKGSSGDTANPFPVPSLPNGNSKPG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 QDPPKSASSTKSNHKDSSIPKQRRVEGKGSRSSSEHKGSSGDTANPFPVPSLPNGNSKPG
              910       920       930       940       950       960

           960       970       980       990      1000      1010   
pF1KB9 KPQVKFDKQQADLHMREAKKMKQKAELMTDRVGKAFKYLEAVLSFIECGIATESESQSSK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 KPQVKFDKQQADLHMREAKKMKQKAELMTDRVGKAFKYLEAVLSFIECGIATESESQSSK
              970       980       990      1000      1010      1020

          1020      1030      1040      1050      1060      1070   
pF1KB9 SAYSVYSETVDLIKFIMSLKSFSDATAPTQEKIFAVLCMRCQSILNMAMFRCKKDIAIKY
       :::::::::::::::::::::::::::::::::::::                       
XP_005 SAYSVYSETVDLIKFIMSLKSFSDATAPTQEKIFAVL                       
             1030      1040      1050                              

          1080      1090      1100      1110      1120      1130   
pF1KB9 SRTLNKHFESSSKVAQAPSPCIARSTGTPSPLSPMPSPASSVGSQSSAGSVGSSGVAATI

>>XP_016863704 (OMIM: 159557) PREDICTED: AF4/FMR2 family  (849 aa)
 initn: 5604 init1: 5604 opt: 5604  Z-score: 2280.6  bits: 433.5 E(85289): 2.7e-120
Smith-Waterman score: 5604; 100.0% identity (100.0% similar) in 849 aa overlap (363-1211:1-849)

            340       350       360       370       380       390  
pF1KB9 AKLTKLKMPSQSVEQTYSNEVHCVEEILKEMTHSWPPPLTAIHTPSTAEPSKFPFPTKDS
                                     ::::::::::::::::::::::::::::::
XP_016                               MTHSWPPPLTAIHTPSTAEPSKFPFPTKDS
                                             10        20        30

            400       410       420       430       440       450  
pF1KB9 QHVSSVTQNQKQYDTSSKTHSNSQQGTSSMLEDDLQLSDSEDSDSEQTPEKPPSSSAPPS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QHVSSVTQNQKQYDTSSKTHSNSQQGTSSMLEDDLQLSDSEDSDSEQTPEKPPSSSAPPS
               40        50        60        70        80        90

            460       470       480       490       500       510  
pF1KB9 APQSLPEPVASAHSSSAESESTSDSDSSSDSESESSSSDSEENEPLETPAPEPEPPTTNK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 APQSLPEPVASAHSSSAESESTSDSDSSSDSESESSSSDSEENEPLETPAPEPEPPTTNK
              100       110       120       130       140       150

            520       530       540       550       560       570  
pF1KB9 WQLDNWLTKVSQPAAPPEGPRSTEPPRRHPESKGSSDSATSQEHSESKDPPPKSSSKAPR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 WQLDNWLTKVSQPAAPPEGPRSTEPPRRHPESKGSSDSATSQEHSESKDPPPKSSSKAPR
              160       170       180       190       200       210

            580       590       600       610       620       630  
pF1KB9 APPEAPHPGKRSCQKSPAQQEPPQRQTVGTKQPKKPVKASARAGSRTSLQGEREPGLLPY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 APPEAPHPGKRSCQKSPAQQEPPQRQTVGTKQPKKPVKASARAGSRTSLQGEREPGLLPY
              220       230       240       250       260       270

            640       650       660       670       680       690  
pF1KB9 GSRDQTSKDKPKVKTKGRPRAAASNEPKPAVPPSSEKKKHKSSLPAPSKALSGPEPAKDN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GSRDQTSKDKPKVKTKGRPRAAASNEPKPAVPPSSEKKKHKSSLPAPSKALSGPEPAKDN
              280       290       300       310       320       330

            700       710       720       730       740       750  
pF1KB9 VEDRTPEHFALVPLTESQGPPHSGSGSRTSGCRQAVVVQEDSRKDRLPLPLRDTKLLSPL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VEDRTPEHFALVPLTESQGPPHSGSGSRTSGCRQAVVVQEDSRKDRLPLPLRDTKLLSPL
              340       350       360       370       380       390

            760       770       780       790       800       810  
pF1KB9 RDTPPPQSLMVKITLDLLSRIPQPPGKGSRQRKAEDKQPPAGKKHSSEKRSSDSSSKLAK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RDTPPPQSLMVKITLDLLSRIPQPPGKGSRQRKAEDKQPPAGKKHSSEKRSSDSSSKLAK
              400       410       420       430       440       450

            820       830       840       850       860       870  
pF1KB9 KRKGEAERDCDNKKIRLEKEIKSQSSSSSSSHKESSKTKPSRPSSQSSKKEMLPPPPVSS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KRKGEAERDCDNKKIRLEKEIKSQSSSSSSSHKESSKTKPSRPSSQSSKKEMLPPPPVSS
              460       470       480       490       500       510

            880       890       900       910       920       930  
pF1KB9 SSQKPAKPALKRSRREADTCGQDPPKSASSTKSNHKDSSIPKQRRVEGKGSRSSSEHKGS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SSQKPAKPALKRSRREADTCGQDPPKSASSTKSNHKDSSIPKQRRVEGKGSRSSSEHKGS
              520       530       540       550       560       570

            940       950       960       970       980       990  
pF1KB9 SGDTANPFPVPSLPNGNSKPGKPQVKFDKQQADLHMREAKKMKQKAELMTDRVGKAFKYL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SGDTANPFPVPSLPNGNSKPGKPQVKFDKQQADLHMREAKKMKQKAELMTDRVGKAFKYL
              580       590       600       610       620       630

           1000      1010      1020      1030      1040      1050  
pF1KB9 EAVLSFIECGIATESESQSSKSAYSVYSETVDLIKFIMSLKSFSDATAPTQEKIFAVLCM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EAVLSFIECGIATESESQSSKSAYSVYSETVDLIKFIMSLKSFSDATAPTQEKIFAVLCM
              640       650       660       670       680       690

           1060      1070      1080      1090      1100      1110  
pF1KB9 RCQSILNMAMFRCKKDIAIKYSRTLNKHFESSSKVAQAPSPCIARSTGTPSPLSPMPSPA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RCQSILNMAMFRCKKDIAIKYSRTLNKHFESSSKVAQAPSPCIARSTGTPSPLSPMPSPA
              700       710       720       730       740       750

           1120      1130      1140      1150      1160      1170  
pF1KB9 SSVGSQSSAGSVGSSGVAATISTPVTIQNMTSSYVTITSHVLTAFDLWEQAEALTRKNKE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SSVGSQSSAGSVGSSGVAATISTPVTIQNMTSSYVTITSHVLTAFDLWEQAEALTRKNKE
              760       770       780       790       800       810

           1180      1190      1200      1210 
pF1KB9 FFARLSTNVCTLALNSSLVDLVHYTRQGFQQLQELTKTP
       :::::::::::::::::::::::::::::::::::::::
XP_016 FFARLSTNVCTLALNSSLVDLVHYTRQGFQQLQELTKTP
              820       830       840         

>>NP_001300889 (OMIM: 159557) AF4/FMR2 family member 1 i  (849 aa)
 initn: 5604 init1: 5604 opt: 5604  Z-score: 2280.6  bits: 433.5 E(85289): 2.7e-120
Smith-Waterman score: 5604; 100.0% identity (100.0% similar) in 849 aa overlap (363-1211:1-849)

            340       350       360       370       380       390  
pF1KB9 AKLTKLKMPSQSVEQTYSNEVHCVEEILKEMTHSWPPPLTAIHTPSTAEPSKFPFPTKDS
                                     ::::::::::::::::::::::::::::::
NP_001                               MTHSWPPPLTAIHTPSTAEPSKFPFPTKDS
                                             10        20        30

            400       410       420       430       440       450  
pF1KB9 QHVSSVTQNQKQYDTSSKTHSNSQQGTSSMLEDDLQLSDSEDSDSEQTPEKPPSSSAPPS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QHVSSVTQNQKQYDTSSKTHSNSQQGTSSMLEDDLQLSDSEDSDSEQTPEKPPSSSAPPS
               40        50        60        70        80        90

            460       470       480       490       500       510  
pF1KB9 APQSLPEPVASAHSSSAESESTSDSDSSSDSESESSSSDSEENEPLETPAPEPEPPTTNK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 APQSLPEPVASAHSSSAESESTSDSDSSSDSESESSSSDSEENEPLETPAPEPEPPTTNK
              100       110       120       130       140       150

            520       530       540       550       560       570  
pF1KB9 WQLDNWLTKVSQPAAPPEGPRSTEPPRRHPESKGSSDSATSQEHSESKDPPPKSSSKAPR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 WQLDNWLTKVSQPAAPPEGPRSTEPPRRHPESKGSSDSATSQEHSESKDPPPKSSSKAPR
              160       170       180       190       200       210

            580       590       600       610       620       630  
pF1KB9 APPEAPHPGKRSCQKSPAQQEPPQRQTVGTKQPKKPVKASARAGSRTSLQGEREPGLLPY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 APPEAPHPGKRSCQKSPAQQEPPQRQTVGTKQPKKPVKASARAGSRTSLQGEREPGLLPY
              220       230       240       250       260       270

            640       650       660       670       680       690  
pF1KB9 GSRDQTSKDKPKVKTKGRPRAAASNEPKPAVPPSSEKKKHKSSLPAPSKALSGPEPAKDN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GSRDQTSKDKPKVKTKGRPRAAASNEPKPAVPPSSEKKKHKSSLPAPSKALSGPEPAKDN
              280       290       300       310       320       330

            700       710       720       730       740       750  
pF1KB9 VEDRTPEHFALVPLTESQGPPHSGSGSRTSGCRQAVVVQEDSRKDRLPLPLRDTKLLSPL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VEDRTPEHFALVPLTESQGPPHSGSGSRTSGCRQAVVVQEDSRKDRLPLPLRDTKLLSPL
              340       350       360       370       380       390

            760       770       780       790       800       810  
pF1KB9 RDTPPPQSLMVKITLDLLSRIPQPPGKGSRQRKAEDKQPPAGKKHSSEKRSSDSSSKLAK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RDTPPPQSLMVKITLDLLSRIPQPPGKGSRQRKAEDKQPPAGKKHSSEKRSSDSSSKLAK
              400       410       420       430       440       450

            820       830       840       850       860       870  
pF1KB9 KRKGEAERDCDNKKIRLEKEIKSQSSSSSSSHKESSKTKPSRPSSQSSKKEMLPPPPVSS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KRKGEAERDCDNKKIRLEKEIKSQSSSSSSSHKESSKTKPSRPSSQSSKKEMLPPPPVSS
              460       470       480       490       500       510

            880       890       900       910       920       930  
pF1KB9 SSQKPAKPALKRSRREADTCGQDPPKSASSTKSNHKDSSIPKQRRVEGKGSRSSSEHKGS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SSQKPAKPALKRSRREADTCGQDPPKSASSTKSNHKDSSIPKQRRVEGKGSRSSSEHKGS
              520       530       540       550       560       570

            940       950       960       970       980       990  
pF1KB9 SGDTANPFPVPSLPNGNSKPGKPQVKFDKQQADLHMREAKKMKQKAELMTDRVGKAFKYL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SGDTANPFPVPSLPNGNSKPGKPQVKFDKQQADLHMREAKKMKQKAELMTDRVGKAFKYL
              580       590       600       610       620       630

           1000      1010      1020      1030      1040      1050  
pF1KB9 EAVLSFIECGIATESESQSSKSAYSVYSETVDLIKFIMSLKSFSDATAPTQEKIFAVLCM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EAVLSFIECGIATESESQSSKSAYSVYSETVDLIKFIMSLKSFSDATAPTQEKIFAVLCM
              640       650       660       670       680       690

           1060      1070      1080      1090      1100      1110  
pF1KB9 RCQSILNMAMFRCKKDIAIKYSRTLNKHFESSSKVAQAPSPCIARSTGTPSPLSPMPSPA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RCQSILNMAMFRCKKDIAIKYSRTLNKHFESSSKVAQAPSPCIARSTGTPSPLSPMPSPA
              700       710       720       730       740       750

           1120      1130      1140      1150      1160      1170  
pF1KB9 SSVGSQSSAGSVGSSGVAATISTPVTIQNMTSSYVTITSHVLTAFDLWEQAEALTRKNKE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SSVGSQSSAGSVGSSGVAATISTPVTIQNMTSSYVTITSHVLTAFDLWEQAEALTRKNKE
              760       770       780       790       800       810

           1180      1190      1200      1210 
pF1KB9 FFARLSTNVCTLALNSSLVDLVHYTRQGFQQLQELTKTP
       :::::::::::::::::::::::::::::::::::::::
NP_001 FFARLSTNVCTLALNSSLVDLVHYTRQGFQQLQELTKTP
              820       830       840         




1211 residues in 1 query   sequences
60827320 residues in 85289 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Thu Nov  3 23:46:54 2016 done: Thu Nov  3 23:46:57 2016
 Total Scan time: 19.700 Total Display time:  0.490

Function used was FASTA [36.3.4 Apr, 2011]
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