Result of FASTA (omim) for pF1KB9423
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KB9423, 217 aa
  1>>>pF1KB9423 217 - 217 aa - 217 aa
Library: /omim/omim.rfq.tfa
  60827320 residues in 85289 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 5.0087+/-0.000338; mu= 14.9916+/- 0.021
 mean_var=58.7640+/-12.020, 0's: 0 Z-trim(114.4): 14  B-trim: 0 in 0/51
 Lambda= 0.167309
 statistics sampled from 24140 (24154) to 24140 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.681), E-opt: 0.2 (0.283), width:  16
 Scan time:  5.880

The best scores are:                                      opt bits E(85289)
NP_775739 (OMIM: 609282) MOB kinase activator 1B i ( 216)  857 214.9 8.1e-56
XP_005265766 (OMIM: 609282) PREDICTED: MOB kinase  ( 221)  857 214.9 8.2e-56
NP_001231695 (OMIM: 609282) MOB kinase activator 1 ( 221)  857 214.9 8.2e-56
XP_011530714 (OMIM: 609282) PREDICTED: MOB kinase  ( 240)  857 214.9 8.8e-56
XP_016864326 (OMIM: 609282) PREDICTED: MOB kinase  ( 247)  857 214.9   9e-56
NP_001304039 (OMIM: 609281) MOB kinase activator 1 ( 215)  842 211.3 9.9e-55
NP_060691 (OMIM: 609281) MOB kinase activator 1A i ( 216)  841 211.0 1.2e-54
NP_001304040 (OMIM: 609281) MOB kinase activator 1 ( 258)  841 211.1 1.4e-54
NP_001231696 (OMIM: 609282) MOB kinase activator 1 ( 147)  552 141.2 8.5e-34
NP_001304041 (OMIM: 609281) MOB kinase activator 1 ( 138)  534 136.8 1.6e-32
XP_011531250 (OMIM: 609281) PREDICTED: MOB kinase  ( 180)  534 136.9   2e-32
NP_001165694 (OMIM: 611969) MOB kinase activator 2 ( 268)  440 114.3 1.9e-25
NP_443731 (OMIM: 611969) MOB kinase activator 2 is ( 237)  438 113.8 2.4e-25


>>NP_775739 (OMIM: 609282) MOB kinase activator 1B isofo  (216 aa)
 initn: 874 init1: 770 opt: 857  Z-score: 1123.1  bits: 214.9 E(85289): 8.1e-56
Smith-Waterman score: 857; 55.0% identity (86.1% similar) in 202 aa overlap (14-215:11-211)

               10        20        30        40        50        60
pF1KB9 MSNPFLKQVFNKDKTFRPKRKFEPGTQRFELHKKAQASLNAGLDLRLAVQLPPGEDLNDW
                    :::.::...  :....:: :.:.:.:..: .::.::.:: :::::.:
NP_775    MSFLFGSRSSKTFKPKKNIPEGSHQYELLKHAEATLGSG-NLRMAVMLPEGEDLNEW
                  10        20        30         40        50      

               70        80        90       100       110       120
pF1KB9 VAVHVVDFFNRVNLIYGTISDGCTEQSCPVMSGGPKYEYRWQDEHKFRKPTALSAPRYMD
       :::..:::::..:..::::.: :::.::::::.::::::.: :  ...::   :::.:.:
NP_775 VAVNTVDFFNQINMLYGTITDFCTEESCPVMSAGPKYEYHWADGTNIKKPIKCSAPKYID
         60        70        80        90       100       110      

              130       140       150       160       170       180
pF1KB9 LLMDWIEAQINNEDLFPTNVGTPFPKNFLQTVRKILSRLFRVFVHVYIHHFDRIAQMGSE
        :: :.. :...: :::...:.::::::..... ::.:::::..:.: .::: . :.  :
NP_775 YLMTWVQDQLDDETLFPSKIGVPFPKNFMSVAKTILKRLFRVYAHIYHQHFDPVIQLQEE
        120       130       140       150       160       170      

              190       200       210          
pF1KB9 AHVNTCYKHFYYFVKEFGLIDTKELEPLKEMTARMCH   
       ::.:: .::: .::.::.::: .:: ::.:.  ..     
NP_775 AHLNTSFKHFIFFVQEFNLIDRRELAPLQELIEKLTSKDR
        180       190       200       210      

>>XP_005265766 (OMIM: 609282) PREDICTED: MOB kinase acti  (221 aa)
 initn: 874 init1: 770 opt: 857  Z-score: 1123.0  bits: 214.9 E(85289): 8.2e-56
Smith-Waterman score: 857; 55.0% identity (86.1% similar) in 202 aa overlap (14-215:16-216)

                 10        20        30        40        50        
pF1KB9   MSNPFLKQVFNKDKTFRPKRKFEPGTQRFELHKKAQASLNAGLDLRLAVQLPPGEDLN
                      :::.::...  :....:: :.:.:.:..: .::.::.:: :::::
XP_005 MEGATDVNESGSRSSKTFKPKKNIPEGSHQYELLKHAEATLGSG-NLRMAVMLPEGEDLN
               10        20        30        40         50         

       60        70        80        90       100       110        
pF1KB9 DWVAVHVVDFFNRVNLIYGTISDGCTEQSCPVMSGGPKYEYRWQDEHKFRKPTALSAPRY
       .::::..:::::..:..::::.: :::.::::::.::::::.: :  ...::   :::.:
XP_005 EWVAVNTVDFFNQINMLYGTITDFCTEESCPVMSAGPKYEYHWADGTNIKKPIKCSAPKY
      60        70        80        90       100       110         

      120       130       140       150       160       170        
pF1KB9 MDLLMDWIEAQINNEDLFPTNVGTPFPKNFLQTVRKILSRLFRVFVHVYIHHFDRIAQMG
       .: :: :.. :...: :::...:.::::::..... ::.:::::..:.: .::: . :. 
XP_005 IDYLMTWVQDQLDDETLFPSKIGVPFPKNFMSVAKTILKRLFRVYAHIYHQHFDPVIQLQ
     120       130       140       150       160       170         

      180       190       200       210          
pF1KB9 SEAHVNTCYKHFYYFVKEFGLIDTKELEPLKEMTARMCH   
        :::.:: .::: .::.::.::: .:: ::.:.  ..     
XP_005 EEAHLNTSFKHFIFFVQEFNLIDRRELAPLQELIEKLTSKDR
     180       190       200       210       220 

>>NP_001231695 (OMIM: 609282) MOB kinase activator 1B is  (221 aa)
 initn: 874 init1: 770 opt: 857  Z-score: 1123.0  bits: 214.9 E(85289): 8.2e-56
Smith-Waterman score: 857; 55.0% identity (86.1% similar) in 202 aa overlap (14-215:16-216)

                 10        20        30        40        50        
pF1KB9   MSNPFLKQVFNKDKTFRPKRKFEPGTQRFELHKKAQASLNAGLDLRLAVQLPPGEDLN
                      :::.::...  :....:: :.:.:.:..: .::.::.:: :::::
NP_001 MEGATDVNESGSRSSKTFKPKKNIPEGSHQYELLKHAEATLGSG-NLRMAVMLPEGEDLN
               10        20        30        40         50         

       60        70        80        90       100       110        
pF1KB9 DWVAVHVVDFFNRVNLIYGTISDGCTEQSCPVMSGGPKYEYRWQDEHKFRKPTALSAPRY
       .::::..:::::..:..::::.: :::.::::::.::::::.: :  ...::   :::.:
NP_001 EWVAVNTVDFFNQINMLYGTITDFCTEESCPVMSAGPKYEYHWADGTNIKKPIKCSAPKY
      60        70        80        90       100       110         

      120       130       140       150       160       170        
pF1KB9 MDLLMDWIEAQINNEDLFPTNVGTPFPKNFLQTVRKILSRLFRVFVHVYIHHFDRIAQMG
       .: :: :.. :...: :::...:.::::::..... ::.:::::..:.: .::: . :. 
NP_001 IDYLMTWVQDQLDDETLFPSKIGVPFPKNFMSVAKTILKRLFRVYAHIYHQHFDPVIQLQ
     120       130       140       150       160       170         

      180       190       200       210          
pF1KB9 SEAHVNTCYKHFYYFVKEFGLIDTKELEPLKEMTARMCH   
        :::.:: .::: .::.::.::: .:: ::.:.  ..     
NP_001 EEAHLNTSFKHFIFFVQEFNLIDRRELAPLQELIEKLTSKDR
     180       190       200       210       220 

>>XP_011530714 (OMIM: 609282) PREDICTED: MOB kinase acti  (240 aa)
 initn: 874 init1: 770 opt: 857  Z-score: 1122.4  bits: 214.9 E(85289): 8.8e-56
Smith-Waterman score: 857; 55.0% identity (86.1% similar) in 202 aa overlap (14-215:35-235)

                                10        20        30        40   
pF1KB9                  MSNPFLKQVFNKDKTFRPKRKFEPGTQRFELHKKAQASLNAGL
                                     :::.::...  :....:: :.:.:.:..: 
XP_011 RVDRGAGQPRRTRWASSLAAEETRSGSRSSKTFKPKKNIPEGSHQYELLKHAEATLGSG-
           10        20        30        40        50        60    

            50        60        70        80        90       100   
pF1KB9 DLRLAVQLPPGEDLNDWVAVHVVDFFNRVNLIYGTISDGCTEQSCPVMSGGPKYEYRWQD
       .::.::.:: :::::.::::..:::::..:..::::.: :::.::::::.::::::.: :
XP_011 NLRMAVMLPEGEDLNEWVAVNTVDFFNQINMLYGTITDFCTEESCPVMSAGPKYEYHWAD
            70        80        90       100       110       120   

           110       120       130       140       150       160   
pF1KB9 EHKFRKPTALSAPRYMDLLMDWIEAQINNEDLFPTNVGTPFPKNFLQTVRKILSRLFRVF
         ...::   :::.:.: :: :.. :...: :::...:.::::::..... ::.:::::.
XP_011 GTNIKKPIKCSAPKYIDYLMTWVQDQLDDETLFPSKIGVPFPKNFMSVAKTILKRLFRVY
           130       140       150       160       170       180   

           170       180       190       200       210          
pF1KB9 VHVYIHHFDRIAQMGSEAHVNTCYKHFYYFVKEFGLIDTKELEPLKEMTARMCH   
       .:.: .::: . :.  :::.:: .::: .::.::.::: .:: ::.:.  ..     
XP_011 AHIYHQHFDPVIQLQEEAHLNTSFKHFIFFVQEFNLIDRRELAPLQELIEKLTSKDR
           190       200       210       220       230       240

>>XP_016864326 (OMIM: 609282) PREDICTED: MOB kinase acti  (247 aa)
 initn: 874 init1: 770 opt: 857  Z-score: 1122.2  bits: 214.9 E(85289): 9e-56
Smith-Waterman score: 857; 55.0% identity (86.1% similar) in 202 aa overlap (14-215:42-242)

                                10        20        30        40   
pF1KB9                  MSNPFLKQVFNKDKTFRPKRKFEPGTQRFELHKKAQASLNAGL
                                     :::.::...  :....:: :.:.:.:..: 
XP_016 SFDFPGSGDPFISNPLPATSSWYYSGSRSSKTFKPKKNIPEGSHQYELLKHAEATLGSG-
              20        30        40        50        60        70 

            50        60        70        80        90       100   
pF1KB9 DLRLAVQLPPGEDLNDWVAVHVVDFFNRVNLIYGTISDGCTEQSCPVMSGGPKYEYRWQD
       .::.::.:: :::::.::::..:::::..:..::::.: :::.::::::.::::::.: :
XP_016 NLRMAVMLPEGEDLNEWVAVNTVDFFNQINMLYGTITDFCTEESCPVMSAGPKYEYHWAD
               80        90       100       110       120       130

           110       120       130       140       150       160   
pF1KB9 EHKFRKPTALSAPRYMDLLMDWIEAQINNEDLFPTNVGTPFPKNFLQTVRKILSRLFRVF
         ...::   :::.:.: :: :.. :...: :::...:.::::::..... ::.:::::.
XP_016 GTNIKKPIKCSAPKYIDYLMTWVQDQLDDETLFPSKIGVPFPKNFMSVAKTILKRLFRVY
              140       150       160       170       180       190

           170       180       190       200       210          
pF1KB9 VHVYIHHFDRIAQMGSEAHVNTCYKHFYYFVKEFGLIDTKELEPLKEMTARMCH   
       .:.: .::: . :.  :::.:: .::: .::.::.::: .:: ::.:.  ..     
XP_016 AHIYHQHFDPVIQLQEEAHLNTSFKHFIFFVQEFNLIDRRELAPLQELIEKLTSKDR
              200       210       220       230       240       

>>NP_001304039 (OMIM: 609281) MOB kinase activator 1A is  (215 aa)
 initn: 858 init1: 754 opt: 842  Z-score: 1103.6  bits: 211.3 E(85289): 9.9e-55
Smith-Waterman score: 842; 52.4% identity (85.1% similar) in 208 aa overlap (9-215:4-210)

               10         20        30        40        50         
pF1KB9 MSNPFLKQVFNKD-KTFRPKRKFEPGTQRFELHKKAQASLNAGLDLRLAVQLPPGEDLND
               .:... :::.::...  :....:: :.:.:.:..: .:: ::.:: :::::.
NP_001      MSFLFSRSSKTFKPKKNIPEGSHQYELLKHAEATLGSG-NLRQAVMLPEGEDLNE
                    10        20        30         40        50    

      60        70        80        90       100       110         
pF1KB9 WVAVHVVDFFNRVNLIYGTISDGCTEQSCPVMSGGPKYEYRWQDEHKFRKPTALSAPRYM
       :.::..:::::..:..::::.. ::: ::::::.::.:::.: :  ...::   :::.:.
NP_001 WIAVNTVDFFNQINMLYGTITEFCTEASCPVMSAGPRYEYHWADGTNIKKPIKCSAPKYI
           60        70        80        90       100       110    

     120       130       140       150       160       170         
pF1KB9 DLLMDWIEAQINNEDLFPTNVGTPFPKNFLQTVRKILSRLFRVFVHVYIHHFDRIAQMGS
       : :: :.. :...: :::...:.::::::..... ::.:::::..:.: .::: . :.  
NP_001 DYLMTWVQDQLDDETLFPSKIGVPFPKNFMSVAKTILKRLFRVYAHIYHQHFDSVMQLQE
          120       130       140       150       160       170    

     180       190       200       210          
pF1KB9 EAHVNTCYKHFYYFVKEFGLIDTKELEPLKEMTARMCH   
       :::.:: .::: .::.::.::: .:: ::.:.  ..     
NP_001 EAHLNTSFKHFIFFVQEFNLIDRRELAPLQELIEKLGSKDR
          180       190       200       210     

>>NP_060691 (OMIM: 609281) MOB kinase activator 1A isofo  (216 aa)
 initn: 858 init1: 754 opt: 841  Z-score: 1102.2  bits: 211.0 E(85289): 1.2e-54
Smith-Waterman score: 841; 53.5% identity (85.1% similar) in 202 aa overlap (14-215:11-211)

               10        20        30        40        50        60
pF1KB9 MSNPFLKQVFNKDKTFRPKRKFEPGTQRFELHKKAQASLNAGLDLRLAVQLPPGEDLNDW
                    :::.::...  :....:: :.:.:.:..: .:: ::.:: :::::.:
NP_060    MSFLFSSRSSKTFKPKKNIPEGSHQYELLKHAEATLGSG-NLRQAVMLPEGEDLNEW
                  10        20        30         40        50      

               70        80        90       100       110       120
pF1KB9 VAVHVVDFFNRVNLIYGTISDGCTEQSCPVMSGGPKYEYRWQDEHKFRKPTALSAPRYMD
       .::..:::::..:..::::.. ::: ::::::.::.:::.: :  ...::   :::.:.:
NP_060 IAVNTVDFFNQINMLYGTITEFCTEASCPVMSAGPRYEYHWADGTNIKKPIKCSAPKYID
         60        70        80        90       100       110      

              130       140       150       160       170       180
pF1KB9 LLMDWIEAQINNEDLFPTNVGTPFPKNFLQTVRKILSRLFRVFVHVYIHHFDRIAQMGSE
        :: :.. :...: :::...:.::::::..... ::.:::::..:.: .::: . :.  :
NP_060 YLMTWVQDQLDDETLFPSKIGVPFPKNFMSVAKTILKRLFRVYAHIYHQHFDSVMQLQEE
        120       130       140       150       160       170      

              190       200       210          
pF1KB9 AHVNTCYKHFYYFVKEFGLIDTKELEPLKEMTARMCH   
       ::.:: .::: .::.::.::: .:: ::.:.  ..     
NP_060 AHLNTSFKHFIFFVQEFNLIDRRELAPLQELIEKLGSKDR
        180       190       200       210      

>>NP_001304040 (OMIM: 609281) MOB kinase activator 1A is  (258 aa)
 initn: 858 init1: 754 opt: 841  Z-score: 1101.1  bits: 211.1 E(85289): 1.4e-54
Smith-Waterman score: 841; 53.5% identity (85.1% similar) in 202 aa overlap (14-215:53-253)

                                10        20        30        40   
pF1KB9                  MSNPFLKQVFNKDKTFRPKRKFEPGTQRFELHKKAQASLNAGL
                                     :::.::...  :....:: :.:.:.:..: 
NP_001 SRIVLSSSDSAHLLALILTNFSCPRSSRSSKTFKPKKNIPEGSHQYELLKHAEATLGSG-
             30        40        50        60        70        80  

            50        60        70        80        90       100   
pF1KB9 DLRLAVQLPPGEDLNDWVAVHVVDFFNRVNLIYGTISDGCTEQSCPVMSGGPKYEYRWQD
       .:: ::.:: :::::.:.::..:::::..:..::::.. ::: ::::::.::.:::.: :
NP_001 NLRQAVMLPEGEDLNEWIAVNTVDFFNQINMLYGTITEFCTEASCPVMSAGPRYEYHWAD
              90       100       110       120       130       140 

           110       120       130       140       150       160   
pF1KB9 EHKFRKPTALSAPRYMDLLMDWIEAQINNEDLFPTNVGTPFPKNFLQTVRKILSRLFRVF
         ...::   :::.:.: :: :.. :...: :::...:.::::::..... ::.:::::.
NP_001 GTNIKKPIKCSAPKYIDYLMTWVQDQLDDETLFPSKIGVPFPKNFMSVAKTILKRLFRVY
             150       160       170       180       190       200 

           170       180       190       200       210          
pF1KB9 VHVYIHHFDRIAQMGSEAHVNTCYKHFYYFVKEFGLIDTKELEPLKEMTARMCH   
       .:.: .::: . :.  :::.:: .::: .::.::.::: .:: ::.:.  ..     
NP_001 AHIYHQHFDSVMQLQEEAHLNTSFKHFIFFVQEFNLIDRRELAPLQELIEKLGSKDR
             210       220       230       240       250        

>>NP_001231696 (OMIM: 609282) MOB kinase activator 1B is  (147 aa)
 initn: 569 init1: 465 opt: 552  Z-score: 727.8  bits: 141.2 E(85289): 8.5e-34
Smith-Waterman score: 552; 56.2% identity (87.5% similar) in 128 aa overlap (14-141:11-137)

               10        20        30        40        50        60
pF1KB9 MSNPFLKQVFNKDKTFRPKRKFEPGTQRFELHKKAQASLNAGLDLRLAVQLPPGEDLNDW
                    :::.::...  :....:: :.:.:.:..: .::.::.:: :::::.:
NP_001    MSFLFGSRSSKTFKPKKNIPEGSHQYELLKHAEATLGSG-NLRMAVMLPEGEDLNEW
                  10        20        30         40        50      

               70        80        90       100       110       120
pF1KB9 VAVHVVDFFNRVNLIYGTISDGCTEQSCPVMSGGPKYEYRWQDEHKFRKPTALSAPRYMD
       :::..:::::..:..::::.: :::.::::::.::::::.: :  ...::   :::.:.:
NP_001 VAVNTVDFFNQINMLYGTITDFCTEESCPVMSAGPKYEYHWADGTNIKKPIKCSAPKYID
         60        70        80        90       100       110      

              130       140       150       160       170       180
pF1KB9 LLMDWIEAQINNEDLFPTNVGTPFPKNFLQTVRKILSRLFRVFVHVYIHHFDRIAQMGSE
        :: :.. :...: :::...:                                       
NP_001 YLMTWVQDQLDDETLFPSKIGIINFCKGDPS                             
        120       130       140                                    

>>NP_001304041 (OMIM: 609281) MOB kinase activator 1A is  (138 aa)
 initn: 551 init1: 447 opt: 534  Z-score: 704.7  bits: 136.8 E(85289): 1.6e-32
Smith-Waterman score: 534; 53.9% identity (85.9% similar) in 128 aa overlap (14-141:11-137)

               10        20        30        40        50        60
pF1KB9 MSNPFLKQVFNKDKTFRPKRKFEPGTQRFELHKKAQASLNAGLDLRLAVQLPPGEDLNDW
                    :::.::...  :....:: :.:.:.:..: .:: ::.:: :::::.:
NP_001    MSFLFSSRSSKTFKPKKNIPEGSHQYELLKHAEATLGSG-NLRQAVMLPEGEDLNEW
                  10        20        30         40        50      

               70        80        90       100       110       120
pF1KB9 VAVHVVDFFNRVNLIYGTISDGCTEQSCPVMSGGPKYEYRWQDEHKFRKPTALSAPRYMD
       .::..:::::..:..::::.. ::: ::::::.::.:::.: :  ...::   :::.:.:
NP_001 IAVNTVDFFNQINMLYGTITEFCTEASCPVMSAGPRYEYHWADGTNIKKPIKCSAPKYID
         60        70        80        90       100       110      

              130       140       150       160       170       180
pF1KB9 LLMDWIEAQINNEDLFPTNVGTPFPKNFLQTVRKILSRLFRVFVHVYIHHFDRIAQMGSE
        :: :.. :...: :::...:                                       
NP_001 YLMTWVQDQLDDETLFPSKIGV                                      
        120       130                                              




217 residues in 1 query   sequences
60827320 residues in 85289 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Thu Nov  3 23:18:07 2016 done: Thu Nov  3 23:18:08 2016
 Total Scan time:  5.880 Total Display time:  0.000

Function used was FASTA [36.3.4 Apr, 2011]
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