Result of FASTA (omim) for pF1KB5378
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KB5378, 739 aa
  1>>>pF1KB5378 739 - 739 aa - 739 aa
Library: /omim/omim.rfq.tfa
  60827320 residues in 85289 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 5.9269+/-0.000434; mu= 16.5866+/- 0.027
 mean_var=73.1815+/-15.070, 0's: 0 Z-trim(111.0): 88  B-trim: 944 in 1/52
 Lambda= 0.149925
 statistics sampled from 19348 (19439) to 19348 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.589), E-opt: 0.2 (0.228), width:  16
 Scan time: 12.100

The best scores are:                                      opt bits E(85289)
NP_001240781 (OMIM: 607245,614066) AP-4 complex su ( 739) 4916 1073.3       0
NP_006585 (OMIM: 607245,614066) AP-4 complex subun ( 739) 4916 1073.3       0
XP_016855577 (OMIM: 607245,614066) PREDICTED: AP-4 ( 700) 4655 1016.8       0
NP_001240782 (OMIM: 607245,614066) AP-4 complex su ( 640) 4254 930.1       0
XP_011538826 (OMIM: 607245,614066) PREDICTED: AP-4 ( 664) 4178 913.6       0
XP_011538825 (OMIM: 607245,614066) PREDICTED: AP-4 ( 664) 4178 913.6       0
NP_001295241 (OMIM: 607245,614066) AP-4 complex su ( 571) 3556 779.1       0
XP_016855579 (OMIM: 607245,614066) PREDICTED: AP-4 ( 571) 3556 779.1       0
XP_011538827 (OMIM: 607245,614066) PREDICTED: AP-4 ( 646) 3556 779.1       0
XP_016855582 (OMIM: 607245,614066) PREDICTED: AP-4 ( 405) 2643 581.5 2.2e-165
XP_016855578 (OMIM: 607245,614066) PREDICTED: AP-4 ( 635) 2642 581.4 3.8e-165
XP_016855581 (OMIM: 607245,614066) PREDICTED: AP-4 ( 414) 2446 538.9 1.5e-152
XP_011538830 (OMIM: 607245,614066) PREDICTED: AP-4 ( 414) 2446 538.9 1.5e-152
XP_016855580 (OMIM: 607245,614066) PREDICTED: AP-4 ( 542) 1573 350.2 1.3e-95
XP_016879776 (OMIM: 601025) PREDICTED: AP-2 comple ( 733) 1026 231.9 7.2e-60
XP_005257998 (OMIM: 601025) PREDICTED: AP-2 comple ( 733) 1026 231.9 7.2e-60
XP_016879773 (OMIM: 601025) PREDICTED: AP-2 comple ( 937) 1026 231.9   9e-60
NP_001273 (OMIM: 601025) AP-2 complex subunit beta ( 937) 1026 231.9   9e-60
NP_001025177 (OMIM: 601025) AP-2 complex subunit b ( 951) 1026 231.9 9.1e-60
XP_005257995 (OMIM: 601025) PREDICTED: AP-2 comple ( 951) 1026 231.9 9.1e-60
XP_005257994 (OMIM: 601025) PREDICTED: AP-2 comple ( 951) 1026 231.9 9.1e-60
XP_011522753 (OMIM: 601025) PREDICTED: AP-2 comple ( 969) 1026 231.9 9.3e-60
XP_011522751 (OMIM: 601025) PREDICTED: AP-2 comple ( 983) 1026 231.9 9.4e-60
XP_011522752 (OMIM: 601025) PREDICTED: AP-2 comple ( 983) 1026 231.9 9.4e-60
XP_011522750 (OMIM: 601025) PREDICTED: AP-2 comple ( 983) 1026 231.9 9.4e-60
NP_001159491 (OMIM: 600157) AP-1 complex subunit b ( 919)  996 225.4 7.9e-58
NP_663782 (OMIM: 600157) AP-1 complex subunit beta ( 939)  996 225.4 8.1e-58
NP_001118 (OMIM: 600157) AP-1 complex subunit beta ( 949)  996 225.4 8.2e-58
XP_011522757 (OMIM: 601025) PREDICTED: AP-2 comple ( 880)  962 218.1 1.3e-55
XP_016879775 (OMIM: 601025) PREDICTED: AP-2 comple ( 880)  962 218.1 1.3e-55
XP_016879774 (OMIM: 601025) PREDICTED: AP-2 comple ( 894)  962 218.1 1.3e-55
XP_011522756 (OMIM: 601025) PREDICTED: AP-2 comple ( 926)  962 218.1 1.3e-55
XP_011522755 (OMIM: 601025) PREDICTED: AP-2 comple ( 926)  962 218.1 1.3e-55
XP_011522754 (OMIM: 601025) PREDICTED: AP-2 comple ( 926)  962 218.1 1.3e-55
NP_001265440 (OMIM: 602166) AP-3 complex subunit b (1050)  389 94.2   3e-18
XP_016878130 (OMIM: 602166) PREDICTED: AP-3 comple ( 629)  344 84.3 1.6e-15
XP_016878129 (OMIM: 602166) PREDICTED: AP-3 comple (1058)  344 84.4 2.6e-15
NP_004635 (OMIM: 602166) AP-3 complex subunit beta (1082)  344 84.4 2.6e-15
NP_001265441 (OMIM: 602166) AP-3 complex subunit b (1101)  344 84.4 2.6e-15
XP_005248676 (OMIM: 603401,608233) PREDICTED: AP-3 ( 871)  327 80.7 2.7e-14
XP_016865490 (OMIM: 603401,608233) PREDICTED: AP-3 (1004)  327 80.7 3.1e-14
NP_001258698 (OMIM: 603401,608233) AP-3 complex su (1045)  327 80.8 3.2e-14
XP_005248675 (OMIM: 603401,608233) PREDICTED: AP-3 (1053)  327 80.8 3.3e-14
NP_003655 (OMIM: 603401,608233) AP-3 complex subun (1094)  327 80.8 3.4e-14
NP_057212 (OMIM: 615525) coatomer subunit gamma-1  ( 874)  240 61.9 1.3e-08
NP_057535 (OMIM: 600959) coatomer subunit beta [Ho ( 953)  163 45.3  0.0014
NP_001137534 (OMIM: 600959) coatomer subunit beta  ( 953)  163 45.3  0.0014
NP_001137533 (OMIM: 600959) coatomer subunit beta  ( 953)  163 45.3  0.0014


>>NP_001240781 (OMIM: 607245,614066) AP-4 complex subuni  (739 aa)
 initn: 4916 init1: 4916 opt: 4916  Z-score: 5743.0  bits: 1073.3 E(85289):    0
Smith-Waterman score: 4916; 99.9% identity (99.9% similar) in 739 aa overlap (1-739:1-739)

               10        20        30        40        50        60
pF1KB5 MPYLGSEDVVKELKKALCNPHIQADRLRYRNVIQRVIRYMTQGLDMSGVFMEMVKASATV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MPYLGSEDVVKELKKALCNPHIQADRLRYRNVIQRVIRYMTQGLDMSGVFMEMVKASATV
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB5 DIVQKKLVYLYMCTYAPLKPDLALLAINTLCKDCSDPNPMVRGLALRSMCSLRMPGVQEY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DIVQKKLVYLYMCTYAPLKPDLALLAINTLCKDCSDPNPMVRGLALRSMCSLRMPGVQEY
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB5 IQQPILNGLRDKASYVRRVAVLGCAKMHNLHGDSEVDGALVNELYSLLRDQDPIVVVNCL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IQQPILNGLRDKASYVRRVAVLGCAKMHNLHGDSEVDGALVNELYSLLRDQDPIVVVNCL
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB5 RSLEEILKQEGGVVINKPIAHHLLNRMSKLDQWGQAEVLNFLLRYQPRSEEELFDILNLL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RSLEEILKQEGGVVINKPIAHHLLNRMSKLDQWGQAEVLNFLLRYQPRSEEELFDILNLL
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB5 DSFLKSSSPGVVMGATKLFLILAKMFPHVQTDVLVRVKGPLLAACSSESRELCFVALCHV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DSFLKSSSPGVVMGATKLFLILAKMFPHVQTDVLVRVKGPLLAACSSESRELCFVALCHV
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KB5 RQILHSLPGHFSSHYKKFFCSYSEPHYIKLQKVEVLCELVNDENVQQVLEELRGYCTDVS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RQILHSLPGHFSSHYKKFFCSYSEPHYIKLQKVEVLCELVNDENVQQVLEELRGYCTDVS
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KB5 ADFAQAAIFAIGGIARTYTDQCVQILTELLGLRQEHITTVVVQTFRDLVWLCPQCTEAVC
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ADFAQAAIFAIGGIARTYTDQCVQILTELLGLRQEHITTVVVQTFRDLVWLCPQCTEAVC
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KB5 QALPGCEENIQDSEGKQALIWLLGVHGERIPNAPYVLEDFVENVKSETFPAVKMELLTAS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: 
NP_001 QALPGCEENIQDSEGKQALIWLLGVHGERIPNAPYVLEDFVENVKSETFPAVKMELLTAL
              430       440       450       460       470       480

              490       500       510       520       530       540
pF1KB5 LRLFLSRPAECQDMLGRLLYYCIEEEKDMAVRDRGLFYYRLLLVGIDEVKRILCSPKSDP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LRLFLSRPAECQDMLGRLLYYCIEEEKDMAVRDRGLFYYRLLLVGIDEVKRILCSPKSDP
              490       500       510       520       530       540

              550       560       570       580       590       600
pF1KB5 TLGLLEDPAERPVNSWASDFNTLVPVYGKAHWATISKCQGAERCDPELPKTSSFAASGPL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TLGLLEDPAERPVNSWASDFNTLVPVYGKAHWATISKCQGAERCDPELPKTSSFAASGPL
              550       560       570       580       590       600

              610       620       630       640       650       660
pF1KB5 IPEENKERVQELPDSGALMLVPNRQLTADYFEKTWLSLKVAHQQVLPWRGEFHPDTLQMA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IPEENKERVQELPDSGALMLVPNRQLTADYFEKTWLSLKVAHQQVLPWRGEFHPDTLQMA
              610       620       630       640       650       660

              670       680       690       700       710       720
pF1KB5 LQVVNIQTIAMSRAGSRPWKAYLSAQDDTGCLFLTELLLEPGNSEMQISVKQNEARTETL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LQVVNIQTIAMSRAGSRPWKAYLSAQDDTGCLFLTELLLEPGNSEMQISVKQNEARTETL
              670       680       690       700       710       720

              730         
pF1KB5 NSFISVLETVIGTIEEIKS
       :::::::::::::::::::
NP_001 NSFISVLETVIGTIEEIKS
              730         

>>NP_006585 (OMIM: 607245,614066) AP-4 complex subunit b  (739 aa)
 initn: 4916 init1: 4916 opt: 4916  Z-score: 5743.0  bits: 1073.3 E(85289):    0
Smith-Waterman score: 4916; 99.9% identity (99.9% similar) in 739 aa overlap (1-739:1-739)

               10        20        30        40        50        60
pF1KB5 MPYLGSEDVVKELKKALCNPHIQADRLRYRNVIQRVIRYMTQGLDMSGVFMEMVKASATV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 MPYLGSEDVVKELKKALCNPHIQADRLRYRNVIQRVIRYMTQGLDMSGVFMEMVKASATV
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB5 DIVQKKLVYLYMCTYAPLKPDLALLAINTLCKDCSDPNPMVRGLALRSMCSLRMPGVQEY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 DIVQKKLVYLYMCTYAPLKPDLALLAINTLCKDCSDPNPMVRGLALRSMCSLRMPGVQEY
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB5 IQQPILNGLRDKASYVRRVAVLGCAKMHNLHGDSEVDGALVNELYSLLRDQDPIVVVNCL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 IQQPILNGLRDKASYVRRVAVLGCAKMHNLHGDSEVDGALVNELYSLLRDQDPIVVVNCL
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB5 RSLEEILKQEGGVVINKPIAHHLLNRMSKLDQWGQAEVLNFLLRYQPRSEEELFDILNLL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 RSLEEILKQEGGVVINKPIAHHLLNRMSKLDQWGQAEVLNFLLRYQPRSEEELFDILNLL
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB5 DSFLKSSSPGVVMGATKLFLILAKMFPHVQTDVLVRVKGPLLAACSSESRELCFVALCHV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 DSFLKSSSPGVVMGATKLFLILAKMFPHVQTDVLVRVKGPLLAACSSESRELCFVALCHV
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KB5 RQILHSLPGHFSSHYKKFFCSYSEPHYIKLQKVEVLCELVNDENVQQVLEELRGYCTDVS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 RQILHSLPGHFSSHYKKFFCSYSEPHYIKLQKVEVLCELVNDENVQQVLEELRGYCTDVS
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KB5 ADFAQAAIFAIGGIARTYTDQCVQILTELLGLRQEHITTVVVQTFRDLVWLCPQCTEAVC
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 ADFAQAAIFAIGGIARTYTDQCVQILTELLGLRQEHITTVVVQTFRDLVWLCPQCTEAVC
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KB5 QALPGCEENIQDSEGKQALIWLLGVHGERIPNAPYVLEDFVENVKSETFPAVKMELLTAS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: 
NP_006 QALPGCEENIQDSEGKQALIWLLGVHGERIPNAPYVLEDFVENVKSETFPAVKMELLTAL
              430       440       450       460       470       480

              490       500       510       520       530       540
pF1KB5 LRLFLSRPAECQDMLGRLLYYCIEEEKDMAVRDRGLFYYRLLLVGIDEVKRILCSPKSDP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 LRLFLSRPAECQDMLGRLLYYCIEEEKDMAVRDRGLFYYRLLLVGIDEVKRILCSPKSDP
              490       500       510       520       530       540

              550       560       570       580       590       600
pF1KB5 TLGLLEDPAERPVNSWASDFNTLVPVYGKAHWATISKCQGAERCDPELPKTSSFAASGPL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 TLGLLEDPAERPVNSWASDFNTLVPVYGKAHWATISKCQGAERCDPELPKTSSFAASGPL
              550       560       570       580       590       600

              610       620       630       640       650       660
pF1KB5 IPEENKERVQELPDSGALMLVPNRQLTADYFEKTWLSLKVAHQQVLPWRGEFHPDTLQMA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 IPEENKERVQELPDSGALMLVPNRQLTADYFEKTWLSLKVAHQQVLPWRGEFHPDTLQMA
              610       620       630       640       650       660

              670       680       690       700       710       720
pF1KB5 LQVVNIQTIAMSRAGSRPWKAYLSAQDDTGCLFLTELLLEPGNSEMQISVKQNEARTETL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 LQVVNIQTIAMSRAGSRPWKAYLSAQDDTGCLFLTELLLEPGNSEMQISVKQNEARTETL
              670       680       690       700       710       720

              730         
pF1KB5 NSFISVLETVIGTIEEIKS
       :::::::::::::::::::
NP_006 NSFISVLETVIGTIEEIKS
              730         

>>XP_016855577 (OMIM: 607245,614066) PREDICTED: AP-4 com  (700 aa)
 initn: 4655 init1: 4655 opt: 4655  Z-score: 5438.3  bits: 1016.8 E(85289):    0
Smith-Waterman score: 4655; 99.9% identity (99.9% similar) in 700 aa overlap (40-739:1-700)

      10        20        30        40        50        60         
pF1KB5 VKELKKALCNPHIQADRLRYRNVIQRVIRYMTQGLDMSGVFMEMVKASATVDIVQKKLVY
                                     ::::::::::::::::::::::::::::::
XP_016                               MTQGLDMSGVFMEMVKASATVDIVQKKLVY
                                             10        20        30

      70        80        90       100       110       120         
pF1KB5 LYMCTYAPLKPDLALLAINTLCKDCSDPNPMVRGLALRSMCSLRMPGVQEYIQQPILNGL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LYMCTYAPLKPDLALLAINTLCKDCSDPNPMVRGLALRSMCSLRMPGVQEYIQQPILNGL
               40        50        60        70        80        90

     130       140       150       160       170       180         
pF1KB5 RDKASYVRRVAVLGCAKMHNLHGDSEVDGALVNELYSLLRDQDPIVVVNCLRSLEEILKQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RDKASYVRRVAVLGCAKMHNLHGDSEVDGALVNELYSLLRDQDPIVVVNCLRSLEEILKQ
              100       110       120       130       140       150

     190       200       210       220       230       240         
pF1KB5 EGGVVINKPIAHHLLNRMSKLDQWGQAEVLNFLLRYQPRSEEELFDILNLLDSFLKSSSP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EGGVVINKPIAHHLLNRMSKLDQWGQAEVLNFLLRYQPRSEEELFDILNLLDSFLKSSSP
              160       170       180       190       200       210

     250       260       270       280       290       300         
pF1KB5 GVVMGATKLFLILAKMFPHVQTDVLVRVKGPLLAACSSESRELCFVALCHVRQILHSLPG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GVVMGATKLFLILAKMFPHVQTDVLVRVKGPLLAACSSESRELCFVALCHVRQILHSLPG
              220       230       240       250       260       270

     310       320       330       340       350       360         
pF1KB5 HFSSHYKKFFCSYSEPHYIKLQKVEVLCELVNDENVQQVLEELRGYCTDVSADFAQAAIF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 HFSSHYKKFFCSYSEPHYIKLQKVEVLCELVNDENVQQVLEELRGYCTDVSADFAQAAIF
              280       290       300       310       320       330

     370       380       390       400       410       420         
pF1KB5 AIGGIARTYTDQCVQILTELLGLRQEHITTVVVQTFRDLVWLCPQCTEAVCQALPGCEEN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AIGGIARTYTDQCVQILTELLGLRQEHITTVVVQTFRDLVWLCPQCTEAVCQALPGCEEN
              340       350       360       370       380       390

     430       440       450       460       470       480         
pF1KB5 IQDSEGKQALIWLLGVHGERIPNAPYVLEDFVENVKSETFPAVKMELLTASLRLFLSRPA
       :::::::::::::::::::::::::::::::::::::::::::::::::: :::::::::
XP_016 IQDSEGKQALIWLLGVHGERIPNAPYVLEDFVENVKSETFPAVKMELLTALLRLFLSRPA
              400       410       420       430       440       450

     490       500       510       520       530       540         
pF1KB5 ECQDMLGRLLYYCIEEEKDMAVRDRGLFYYRLLLVGIDEVKRILCSPKSDPTLGLLEDPA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ECQDMLGRLLYYCIEEEKDMAVRDRGLFYYRLLLVGIDEVKRILCSPKSDPTLGLLEDPA
              460       470       480       490       500       510

     550       560       570       580       590       600         
pF1KB5 ERPVNSWASDFNTLVPVYGKAHWATISKCQGAERCDPELPKTSSFAASGPLIPEENKERV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ERPVNSWASDFNTLVPVYGKAHWATISKCQGAERCDPELPKTSSFAASGPLIPEENKERV
              520       530       540       550       560       570

     610       620       630       640       650       660         
pF1KB5 QELPDSGALMLVPNRQLTADYFEKTWLSLKVAHQQVLPWRGEFHPDTLQMALQVVNIQTI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QELPDSGALMLVPNRQLTADYFEKTWLSLKVAHQQVLPWRGEFHPDTLQMALQVVNIQTI
              580       590       600       610       620       630

     670       680       690       700       710       720         
pF1KB5 AMSRAGSRPWKAYLSAQDDTGCLFLTELLLEPGNSEMQISVKQNEARTETLNSFISVLET
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AMSRAGSRPWKAYLSAQDDTGCLFLTELLLEPGNSEMQISVKQNEARTETLNSFISVLET
              640       650       660       670       680       690

     730         
pF1KB5 VIGTIEEIKS
       ::::::::::
XP_016 VIGTIEEIKS
              700

>>NP_001240782 (OMIM: 607245,614066) AP-4 complex subuni  (640 aa)
 initn: 4254 init1: 4254 opt: 4254  Z-score: 4970.1  bits: 930.1 E(85289):    0
Smith-Waterman score: 4254; 99.8% identity (99.8% similar) in 640 aa overlap (100-739:1-640)

      70        80        90       100       110       120         
pF1KB5 LYMCTYAPLKPDLALLAINTLCKDCSDPNPMVRGLALRSMCSLRMPGVQEYIQQPILNGL
                                     ::::::::::::::::::::::::::::::
NP_001                               MVRGLALRSMCSLRMPGVQEYIQQPILNGL
                                             10        20        30

     130       140       150       160       170       180         
pF1KB5 RDKASYVRRVAVLGCAKMHNLHGDSEVDGALVNELYSLLRDQDPIVVVNCLRSLEEILKQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RDKASYVRRVAVLGCAKMHNLHGDSEVDGALVNELYSLLRDQDPIVVVNCLRSLEEILKQ
               40        50        60        70        80        90

     190       200       210       220       230       240         
pF1KB5 EGGVVINKPIAHHLLNRMSKLDQWGQAEVLNFLLRYQPRSEEELFDILNLLDSFLKSSSP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EGGVVINKPIAHHLLNRMSKLDQWGQAEVLNFLLRYQPRSEEELFDILNLLDSFLKSSSP
              100       110       120       130       140       150

     250       260       270       280       290       300         
pF1KB5 GVVMGATKLFLILAKMFPHVQTDVLVRVKGPLLAACSSESRELCFVALCHVRQILHSLPG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GVVMGATKLFLILAKMFPHVQTDVLVRVKGPLLAACSSESRELCFVALCHVRQILHSLPG
              160       170       180       190       200       210

     310       320       330       340       350       360         
pF1KB5 HFSSHYKKFFCSYSEPHYIKLQKVEVLCELVNDENVQQVLEELRGYCTDVSADFAQAAIF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 HFSSHYKKFFCSYSEPHYIKLQKVEVLCELVNDENVQQVLEELRGYCTDVSADFAQAAIF
              220       230       240       250       260       270

     370       380       390       400       410       420         
pF1KB5 AIGGIARTYTDQCVQILTELLGLRQEHITTVVVQTFRDLVWLCPQCTEAVCQALPGCEEN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AIGGIARTYTDQCVQILTELLGLRQEHITTVVVQTFRDLVWLCPQCTEAVCQALPGCEEN
              280       290       300       310       320       330

     430       440       450       460       470       480         
pF1KB5 IQDSEGKQALIWLLGVHGERIPNAPYVLEDFVENVKSETFPAVKMELLTASLRLFLSRPA
       :::::::::::::::::::::::::::::::::::::::::::::::::: :::::::::
NP_001 IQDSEGKQALIWLLGVHGERIPNAPYVLEDFVENVKSETFPAVKMELLTALLRLFLSRPA
              340       350       360       370       380       390

     490       500       510       520       530       540         
pF1KB5 ECQDMLGRLLYYCIEEEKDMAVRDRGLFYYRLLLVGIDEVKRILCSPKSDPTLGLLEDPA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ECQDMLGRLLYYCIEEEKDMAVRDRGLFYYRLLLVGIDEVKRILCSPKSDPTLGLLEDPA
              400       410       420       430       440       450

     550       560       570       580       590       600         
pF1KB5 ERPVNSWASDFNTLVPVYGKAHWATISKCQGAERCDPELPKTSSFAASGPLIPEENKERV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ERPVNSWASDFNTLVPVYGKAHWATISKCQGAERCDPELPKTSSFAASGPLIPEENKERV
              460       470       480       490       500       510

     610       620       630       640       650       660         
pF1KB5 QELPDSGALMLVPNRQLTADYFEKTWLSLKVAHQQVLPWRGEFHPDTLQMALQVVNIQTI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QELPDSGALMLVPNRQLTADYFEKTWLSLKVAHQQVLPWRGEFHPDTLQMALQVVNIQTI
              520       530       540       550       560       570

     670       680       690       700       710       720         
pF1KB5 AMSRAGSRPWKAYLSAQDDTGCLFLTELLLEPGNSEMQISVKQNEARTETLNSFISVLET
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AMSRAGSRPWKAYLSAQDDTGCLFLTELLLEPGNSEMQISVKQNEARTETLNSFISVLET
              580       590       600       610       620       630

     730         
pF1KB5 VIGTIEEIKS
       ::::::::::
NP_001 VIGTIEEIKS
              640

>>XP_011538826 (OMIM: 607245,614066) PREDICTED: AP-4 com  (664 aa)
 initn: 4172 init1: 4172 opt: 4178  Z-score: 4881.0  bits: 913.6 E(85289):    0
Smith-Waterman score: 4256; 89.7% identity (89.7% similar) in 739 aa overlap (1-739:1-664)

               10        20        30        40        50        60
pF1KB5 MPYLGSEDVVKELKKALCNPHIQADRLRYRNVIQRVIRYMTQGLDMSGVFMEMVKASATV
       ::::::::::::::::::::::::::::::::::::::                      
XP_011 MPYLGSEDVVKELKKALCNPHIQADRLRYRNVIQRVIR----------------------
               10        20        30                              

               70        80        90       100       110       120
pF1KB5 DIVQKKLVYLYMCTYAPLKPDLALLAINTLCKDCSDPNPMVRGLALRSMCSLRMPGVQEY
                                                            :::::::
XP_011 -----------------------------------------------------MPGVQEY
                                                            40     

              130       140       150       160       170       180
pF1KB5 IQQPILNGLRDKASYVRRVAVLGCAKMHNLHGDSEVDGALVNELYSLLRDQDPIVVVNCL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 IQQPILNGLRDKASYVRRVAVLGCAKMHNLHGDSEVDGALVNELYSLLRDQDPIVVVNCL
          50        60        70        80        90       100     

              190       200       210       220       230       240
pF1KB5 RSLEEILKQEGGVVINKPIAHHLLNRMSKLDQWGQAEVLNFLLRYQPRSEEELFDILNLL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RSLEEILKQEGGVVINKPIAHHLLNRMSKLDQWGQAEVLNFLLRYQPRSEEELFDILNLL
         110       120       130       140       150       160     

              250       260       270       280       290       300
pF1KB5 DSFLKSSSPGVVMGATKLFLILAKMFPHVQTDVLVRVKGPLLAACSSESRELCFVALCHV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DSFLKSSSPGVVMGATKLFLILAKMFPHVQTDVLVRVKGPLLAACSSESRELCFVALCHV
         170       180       190       200       210       220     

              310       320       330       340       350       360
pF1KB5 RQILHSLPGHFSSHYKKFFCSYSEPHYIKLQKVEVLCELVNDENVQQVLEELRGYCTDVS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RQILHSLPGHFSSHYKKFFCSYSEPHYIKLQKVEVLCELVNDENVQQVLEELRGYCTDVS
         230       240       250       260       270       280     

              370       380       390       400       410       420
pF1KB5 ADFAQAAIFAIGGIARTYTDQCVQILTELLGLRQEHITTVVVQTFRDLVWLCPQCTEAVC
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ADFAQAAIFAIGGIARTYTDQCVQILTELLGLRQEHITTVVVQTFRDLVWLCPQCTEAVC
         290       300       310       320       330       340     

              430       440       450       460       470       480
pF1KB5 QALPGCEENIQDSEGKQALIWLLGVHGERIPNAPYVLEDFVENVKSETFPAVKMELLTAS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: 
XP_011 QALPGCEENIQDSEGKQALIWLLGVHGERIPNAPYVLEDFVENVKSETFPAVKMELLTAL
         350       360       370       380       390       400     

              490       500       510       520       530       540
pF1KB5 LRLFLSRPAECQDMLGRLLYYCIEEEKDMAVRDRGLFYYRLLLVGIDEVKRILCSPKSDP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LRLFLSRPAECQDMLGRLLYYCIEEEKDMAVRDRGLFYYRLLLVGIDEVKRILCSPKSDP
         410       420       430       440       450       460     

              550       560       570       580       590       600
pF1KB5 TLGLLEDPAERPVNSWASDFNTLVPVYGKAHWATISKCQGAERCDPELPKTSSFAASGPL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TLGLLEDPAERPVNSWASDFNTLVPVYGKAHWATISKCQGAERCDPELPKTSSFAASGPL
         470       480       490       500       510       520     

              610       620       630       640       650       660
pF1KB5 IPEENKERVQELPDSGALMLVPNRQLTADYFEKTWLSLKVAHQQVLPWRGEFHPDTLQMA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 IPEENKERVQELPDSGALMLVPNRQLTADYFEKTWLSLKVAHQQVLPWRGEFHPDTLQMA
         530       540       550       560       570       580     

              670       680       690       700       710       720
pF1KB5 LQVVNIQTIAMSRAGSRPWKAYLSAQDDTGCLFLTELLLEPGNSEMQISVKQNEARTETL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LQVVNIQTIAMSRAGSRPWKAYLSAQDDTGCLFLTELLLEPGNSEMQISVKQNEARTETL
         590       600       610       620       630       640     

              730         
pF1KB5 NSFISVLETVIGTIEEIKS
       :::::::::::::::::::
XP_011 NSFISVLETVIGTIEEIKS
         650       660    

>>XP_011538825 (OMIM: 607245,614066) PREDICTED: AP-4 com  (664 aa)
 initn: 4172 init1: 4172 opt: 4178  Z-score: 4881.0  bits: 913.6 E(85289):    0
Smith-Waterman score: 4256; 89.7% identity (89.7% similar) in 739 aa overlap (1-739:1-664)

               10        20        30        40        50        60
pF1KB5 MPYLGSEDVVKELKKALCNPHIQADRLRYRNVIQRVIRYMTQGLDMSGVFMEMVKASATV
       ::::::::::::::::::::::::::::::::::::::                      
XP_011 MPYLGSEDVVKELKKALCNPHIQADRLRYRNVIQRVIR----------------------
               10        20        30                              

               70        80        90       100       110       120
pF1KB5 DIVQKKLVYLYMCTYAPLKPDLALLAINTLCKDCSDPNPMVRGLALRSMCSLRMPGVQEY
                                                            :::::::
XP_011 -----------------------------------------------------MPGVQEY
                                                            40     

              130       140       150       160       170       180
pF1KB5 IQQPILNGLRDKASYVRRVAVLGCAKMHNLHGDSEVDGALVNELYSLLRDQDPIVVVNCL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 IQQPILNGLRDKASYVRRVAVLGCAKMHNLHGDSEVDGALVNELYSLLRDQDPIVVVNCL
          50        60        70        80        90       100     

              190       200       210       220       230       240
pF1KB5 RSLEEILKQEGGVVINKPIAHHLLNRMSKLDQWGQAEVLNFLLRYQPRSEEELFDILNLL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RSLEEILKQEGGVVINKPIAHHLLNRMSKLDQWGQAEVLNFLLRYQPRSEEELFDILNLL
         110       120       130       140       150       160     

              250       260       270       280       290       300
pF1KB5 DSFLKSSSPGVVMGATKLFLILAKMFPHVQTDVLVRVKGPLLAACSSESRELCFVALCHV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DSFLKSSSPGVVMGATKLFLILAKMFPHVQTDVLVRVKGPLLAACSSESRELCFVALCHV
         170       180       190       200       210       220     

              310       320       330       340       350       360
pF1KB5 RQILHSLPGHFSSHYKKFFCSYSEPHYIKLQKVEVLCELVNDENVQQVLEELRGYCTDVS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RQILHSLPGHFSSHYKKFFCSYSEPHYIKLQKVEVLCELVNDENVQQVLEELRGYCTDVS
         230       240       250       260       270       280     

              370       380       390       400       410       420
pF1KB5 ADFAQAAIFAIGGIARTYTDQCVQILTELLGLRQEHITTVVVQTFRDLVWLCPQCTEAVC
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ADFAQAAIFAIGGIARTYTDQCVQILTELLGLRQEHITTVVVQTFRDLVWLCPQCTEAVC
         290       300       310       320       330       340     

              430       440       450       460       470       480
pF1KB5 QALPGCEENIQDSEGKQALIWLLGVHGERIPNAPYVLEDFVENVKSETFPAVKMELLTAS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: 
XP_011 QALPGCEENIQDSEGKQALIWLLGVHGERIPNAPYVLEDFVENVKSETFPAVKMELLTAL
         350       360       370       380       390       400     

              490       500       510       520       530       540
pF1KB5 LRLFLSRPAECQDMLGRLLYYCIEEEKDMAVRDRGLFYYRLLLVGIDEVKRILCSPKSDP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LRLFLSRPAECQDMLGRLLYYCIEEEKDMAVRDRGLFYYRLLLVGIDEVKRILCSPKSDP
         410       420       430       440       450       460     

              550       560       570       580       590       600
pF1KB5 TLGLLEDPAERPVNSWASDFNTLVPVYGKAHWATISKCQGAERCDPELPKTSSFAASGPL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TLGLLEDPAERPVNSWASDFNTLVPVYGKAHWATISKCQGAERCDPELPKTSSFAASGPL
         470       480       490       500       510       520     

              610       620       630       640       650       660
pF1KB5 IPEENKERVQELPDSGALMLVPNRQLTADYFEKTWLSLKVAHQQVLPWRGEFHPDTLQMA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 IPEENKERVQELPDSGALMLVPNRQLTADYFEKTWLSLKVAHQQVLPWRGEFHPDTLQMA
         530       540       550       560       570       580     

              670       680       690       700       710       720
pF1KB5 LQVVNIQTIAMSRAGSRPWKAYLSAQDDTGCLFLTELLLEPGNSEMQISVKQNEARTETL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LQVVNIQTIAMSRAGSRPWKAYLSAQDDTGCLFLTELLLEPGNSEMQISVKQNEARTETL
         590       600       610       620       630       640     

              730         
pF1KB5 NSFISVLETVIGTIEEIKS
       :::::::::::::::::::
XP_011 NSFISVLETVIGTIEEIKS
         650       660    

>>NP_001295241 (OMIM: 607245,614066) AP-4 complex subuni  (571 aa)
 initn: 3556 init1: 3556 opt: 3556  Z-score: 4155.0  bits: 779.1 E(85289):    0
Smith-Waterman score: 3556; 99.8% identity (99.8% similar) in 534 aa overlap (206-739:38-571)

         180       190       200       210       220       230     
pF1KB5 VVNCLRSLEEILKQEGGVVINKPIAHHLLNRMSKLDQWGQAEVLNFLLRYQPRSEEELFD
                                     ::::::::::::::::::::::::::::::
NP_001 DVVKELKKALCNPHIQADRLRYRNVIQRVIRMSKLDQWGQAEVLNFLLRYQPRSEEELFD
        10        20        30        40        50        60       

         240       250       260       270       280       290     
pF1KB5 ILNLLDSFLKSSSPGVVMGATKLFLILAKMFPHVQTDVLVRVKGPLLAACSSESRELCFV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ILNLLDSFLKSSSPGVVMGATKLFLILAKMFPHVQTDVLVRVKGPLLAACSSESRELCFV
        70        80        90       100       110       120       

         300       310       320       330       340       350     
pF1KB5 ALCHVRQILHSLPGHFSSHYKKFFCSYSEPHYIKLQKVEVLCELVNDENVQQVLEELRGY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ALCHVRQILHSLPGHFSSHYKKFFCSYSEPHYIKLQKVEVLCELVNDENVQQVLEELRGY
       130       140       150       160       170       180       

         360       370       380       390       400       410     
pF1KB5 CTDVSADFAQAAIFAIGGIARTYTDQCVQILTELLGLRQEHITTVVVQTFRDLVWLCPQC
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 CTDVSADFAQAAIFAIGGIARTYTDQCVQILTELLGLRQEHITTVVVQTFRDLVWLCPQC
       190       200       210       220       230       240       

         420       430       440       450       460       470     
pF1KB5 TEAVCQALPGCEENIQDSEGKQALIWLLGVHGERIPNAPYVLEDFVENVKSETFPAVKME
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TEAVCQALPGCEENIQDSEGKQALIWLLGVHGERIPNAPYVLEDFVENVKSETFPAVKME
       250       260       270       280       290       300       

         480       490       500       510       520       530     
pF1KB5 LLTASLRLFLSRPAECQDMLGRLLYYCIEEEKDMAVRDRGLFYYRLLLVGIDEVKRILCS
       :::: :::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LLTALLRLFLSRPAECQDMLGRLLYYCIEEEKDMAVRDRGLFYYRLLLVGIDEVKRILCS
       310       320       330       340       350       360       

         540       550       560       570       580       590     
pF1KB5 PKSDPTLGLLEDPAERPVNSWASDFNTLVPVYGKAHWATISKCQGAERCDPELPKTSSFA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PKSDPTLGLLEDPAERPVNSWASDFNTLVPVYGKAHWATISKCQGAERCDPELPKTSSFA
       370       380       390       400       410       420       

         600       610       620       630       640       650     
pF1KB5 ASGPLIPEENKERVQELPDSGALMLVPNRQLTADYFEKTWLSLKVAHQQVLPWRGEFHPD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ASGPLIPEENKERVQELPDSGALMLVPNRQLTADYFEKTWLSLKVAHQQVLPWRGEFHPD
       430       440       450       460       470       480       

         660       670       680       690       700       710     
pF1KB5 TLQMALQVVNIQTIAMSRAGSRPWKAYLSAQDDTGCLFLTELLLEPGNSEMQISVKQNEA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TLQMALQVVNIQTIAMSRAGSRPWKAYLSAQDDTGCLFLTELLLEPGNSEMQISVKQNEA
       490       500       510       520       530       540       

         720       730         
pF1KB5 RTETLNSFISVLETVIGTIEEIKS
       ::::::::::::::::::::::::
NP_001 RTETLNSFISVLETVIGTIEEIKS
       550       560       570 

>--
 initn: 246 init1: 246 opt: 246  Z-score: 285.7  bits: 63.1 E(85289): 3.5e-09
Smith-Waterman score: 246; 100.0% identity (100.0% similar) in 37 aa overlap (1-37:1-37)

               10        20        30        40        50        60
pF1KB5 MPYLGSEDVVKELKKALCNPHIQADRLRYRNVIQRVIRYMTQGLDMSGVFMEMVKASATV
       :::::::::::::::::::::::::::::::::::::                       
NP_001 MPYLGSEDVVKELKKALCNPHIQADRLRYRNVIQRVIRMSKLDQWGQAEVLNFLLRYQPR
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB5 DIVQKKLVYLYMCTYAPLKPDLALLAINTLCKDCSDPNPMVRGLALRSMCSLRMPGVQEY
                                                                   
NP_001 SEEELFDILNLLDSFLKSSSPGVVMGATKLFLILAKMFPHVQTDVLVRVKGPLLAACSSE
               70        80        90       100       110       120

>>XP_016855579 (OMIM: 607245,614066) PREDICTED: AP-4 com  (571 aa)
 initn: 3556 init1: 3556 opt: 3556  Z-score: 4155.0  bits: 779.1 E(85289):    0
Smith-Waterman score: 3556; 99.8% identity (99.8% similar) in 534 aa overlap (206-739:38-571)

         180       190       200       210       220       230     
pF1KB5 VVNCLRSLEEILKQEGGVVINKPIAHHLLNRMSKLDQWGQAEVLNFLLRYQPRSEEELFD
                                     ::::::::::::::::::::::::::::::
XP_016 DVVKELKKALCNPHIQADRLRYRNVIQRVIRMSKLDQWGQAEVLNFLLRYQPRSEEELFD
        10        20        30        40        50        60       

         240       250       260       270       280       290     
pF1KB5 ILNLLDSFLKSSSPGVVMGATKLFLILAKMFPHVQTDVLVRVKGPLLAACSSESRELCFV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ILNLLDSFLKSSSPGVVMGATKLFLILAKMFPHVQTDVLVRVKGPLLAACSSESRELCFV
        70        80        90       100       110       120       

         300       310       320       330       340       350     
pF1KB5 ALCHVRQILHSLPGHFSSHYKKFFCSYSEPHYIKLQKVEVLCELVNDENVQQVLEELRGY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ALCHVRQILHSLPGHFSSHYKKFFCSYSEPHYIKLQKVEVLCELVNDENVQQVLEELRGY
       130       140       150       160       170       180       

         360       370       380       390       400       410     
pF1KB5 CTDVSADFAQAAIFAIGGIARTYTDQCVQILTELLGLRQEHITTVVVQTFRDLVWLCPQC
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 CTDVSADFAQAAIFAIGGIARTYTDQCVQILTELLGLRQEHITTVVVQTFRDLVWLCPQC
       190       200       210       220       230       240       

         420       430       440       450       460       470     
pF1KB5 TEAVCQALPGCEENIQDSEGKQALIWLLGVHGERIPNAPYVLEDFVENVKSETFPAVKME
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TEAVCQALPGCEENIQDSEGKQALIWLLGVHGERIPNAPYVLEDFVENVKSETFPAVKME
       250       260       270       280       290       300       

         480       490       500       510       520       530     
pF1KB5 LLTASLRLFLSRPAECQDMLGRLLYYCIEEEKDMAVRDRGLFYYRLLLVGIDEVKRILCS
       :::: :::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LLTALLRLFLSRPAECQDMLGRLLYYCIEEEKDMAVRDRGLFYYRLLLVGIDEVKRILCS
       310       320       330       340       350       360       

         540       550       560       570       580       590     
pF1KB5 PKSDPTLGLLEDPAERPVNSWASDFNTLVPVYGKAHWATISKCQGAERCDPELPKTSSFA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PKSDPTLGLLEDPAERPVNSWASDFNTLVPVYGKAHWATISKCQGAERCDPELPKTSSFA
       370       380       390       400       410       420       

         600       610       620       630       640       650     
pF1KB5 ASGPLIPEENKERVQELPDSGALMLVPNRQLTADYFEKTWLSLKVAHQQVLPWRGEFHPD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ASGPLIPEENKERVQELPDSGALMLVPNRQLTADYFEKTWLSLKVAHQQVLPWRGEFHPD
       430       440       450       460       470       480       

         660       670       680       690       700       710     
pF1KB5 TLQMALQVVNIQTIAMSRAGSRPWKAYLSAQDDTGCLFLTELLLEPGNSEMQISVKQNEA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TLQMALQVVNIQTIAMSRAGSRPWKAYLSAQDDTGCLFLTELLLEPGNSEMQISVKQNEA
       490       500       510       520       530       540       

         720       730         
pF1KB5 RTETLNSFISVLETVIGTIEEIKS
       ::::::::::::::::::::::::
XP_016 RTETLNSFISVLETVIGTIEEIKS
       550       560       570 

>--
 initn: 246 init1: 246 opt: 246  Z-score: 285.7  bits: 63.1 E(85289): 3.5e-09
Smith-Waterman score: 246; 100.0% identity (100.0% similar) in 37 aa overlap (1-37:1-37)

               10        20        30        40        50        60
pF1KB5 MPYLGSEDVVKELKKALCNPHIQADRLRYRNVIQRVIRYMTQGLDMSGVFMEMVKASATV
       :::::::::::::::::::::::::::::::::::::                       
XP_016 MPYLGSEDVVKELKKALCNPHIQADRLRYRNVIQRVIRMSKLDQWGQAEVLNFLLRYQPR
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB5 DIVQKKLVYLYMCTYAPLKPDLALLAINTLCKDCSDPNPMVRGLALRSMCSLRMPGVQEY
                                                                   
XP_016 SEEELFDILNLLDSFLKSSSPGVVMGATKLFLILAKMFPHVQTDVLVRVKGPLLAACSSE
               70        80        90       100       110       120

>>XP_011538827 (OMIM: 607245,614066) PREDICTED: AP-4 com  (646 aa)
 initn: 3556 init1: 3556 opt: 3556  Z-score: 4154.1  bits: 779.1 E(85289):    0
Smith-Waterman score: 4106; 87.3% identity (87.3% similar) in 739 aa overlap (1-739:1-646)

               10        20        30        40        50        60
pF1KB5 MPYLGSEDVVKELKKALCNPHIQADRLRYRNVIQRVIRYMTQGLDMSGVFMEMVKASATV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MPYLGSEDVVKELKKALCNPHIQADRLRYRNVIQRVIRYMTQGLDMSGVFMEMVKASATV
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB5 DIVQKKLVYLYMCTYAPLKPDLALLAINTLCKDCSDPNPMVRGLALRSMCSLRMPGVQEY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::      
XP_011 DIVQKKLVYLYMCTYAPLKPDLALLAINTLCKDCSDPNPMVRGLALRSMCSLRM------
               70        80        90       100       110          

              130       140       150       160       170       180
pF1KB5 IQQPILNGLRDKASYVRRVAVLGCAKMHNLHGDSEVDGALVNELYSLLRDQDPIVVVNCL
                                                                   
XP_011 ------------------------------------------------------------
                                                                   

              190       200       210       220       230       240
pF1KB5 RSLEEILKQEGGVVINKPIAHHLLNRMSKLDQWGQAEVLNFLLRYQPRSEEELFDILNLL
                                  :::::::::::::::::::::::::::::::::
XP_011 ---------------------------SKLDQWGQAEVLNFLLRYQPRSEEELFDILNLL
                                     120       130       140       

              250       260       270       280       290       300
pF1KB5 DSFLKSSSPGVVMGATKLFLILAKMFPHVQTDVLVRVKGPLLAACSSESRELCFVALCHV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DSFLKSSSPGVVMGATKLFLILAKMFPHVQTDVLVRVKGPLLAACSSESRELCFVALCHV
       150       160       170       180       190       200       

              310       320       330       340       350       360
pF1KB5 RQILHSLPGHFSSHYKKFFCSYSEPHYIKLQKVEVLCELVNDENVQQVLEELRGYCTDVS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RQILHSLPGHFSSHYKKFFCSYSEPHYIKLQKVEVLCELVNDENVQQVLEELRGYCTDVS
       210       220       230       240       250       260       

              370       380       390       400       410       420
pF1KB5 ADFAQAAIFAIGGIARTYTDQCVQILTELLGLRQEHITTVVVQTFRDLVWLCPQCTEAVC
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ADFAQAAIFAIGGIARTYTDQCVQILTELLGLRQEHITTVVVQTFRDLVWLCPQCTEAVC
       270       280       290       300       310       320       

              430       440       450       460       470       480
pF1KB5 QALPGCEENIQDSEGKQALIWLLGVHGERIPNAPYVLEDFVENVKSETFPAVKMELLTAS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: 
XP_011 QALPGCEENIQDSEGKQALIWLLGVHGERIPNAPYVLEDFVENVKSETFPAVKMELLTAL
       330       340       350       360       370       380       

              490       500       510       520       530       540
pF1KB5 LRLFLSRPAECQDMLGRLLYYCIEEEKDMAVRDRGLFYYRLLLVGIDEVKRILCSPKSDP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LRLFLSRPAECQDMLGRLLYYCIEEEKDMAVRDRGLFYYRLLLVGIDEVKRILCSPKSDP
       390       400       410       420       430       440       

              550       560       570       580       590       600
pF1KB5 TLGLLEDPAERPVNSWASDFNTLVPVYGKAHWATISKCQGAERCDPELPKTSSFAASGPL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TLGLLEDPAERPVNSWASDFNTLVPVYGKAHWATISKCQGAERCDPELPKTSSFAASGPL
       450       460       470       480       490       500       

              610       620       630       640       650       660
pF1KB5 IPEENKERVQELPDSGALMLVPNRQLTADYFEKTWLSLKVAHQQVLPWRGEFHPDTLQMA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 IPEENKERVQELPDSGALMLVPNRQLTADYFEKTWLSLKVAHQQVLPWRGEFHPDTLQMA
       510       520       530       540       550       560       

              670       680       690       700       710       720
pF1KB5 LQVVNIQTIAMSRAGSRPWKAYLSAQDDTGCLFLTELLLEPGNSEMQISVKQNEARTETL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LQVVNIQTIAMSRAGSRPWKAYLSAQDDTGCLFLTELLLEPGNSEMQISVKQNEARTETL
       570       580       590       600       610       620       

              730         
pF1KB5 NSFISVLETVIGTIEEIKS
       :::::::::::::::::::
XP_011 NSFISVLETVIGTIEEIKS
       630       640      

>>XP_016855582 (OMIM: 607245,614066) PREDICTED: AP-4 com  (405 aa)
 initn: 2643 init1: 2643 opt: 2643  Z-score: 3090.1  bits: 581.5 E(85289): 2.2e-165
Smith-Waterman score: 2643; 99.5% identity (99.8% similar) in 401 aa overlap (1-401:1-401)

               10        20        30        40        50        60
pF1KB5 MPYLGSEDVVKELKKALCNPHIQADRLRYRNVIQRVIRYMTQGLDMSGVFMEMVKASATV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MPYLGSEDVVKELKKALCNPHIQADRLRYRNVIQRVIRYMTQGLDMSGVFMEMVKASATV
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB5 DIVQKKLVYLYMCTYAPLKPDLALLAINTLCKDCSDPNPMVRGLALRSMCSLRMPGVQEY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DIVQKKLVYLYMCTYAPLKPDLALLAINTLCKDCSDPNPMVRGLALRSMCSLRMPGVQEY
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB5 IQQPILNGLRDKASYVRRVAVLGCAKMHNLHGDSEVDGALVNELYSLLRDQDPIVVVNCL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IQQPILNGLRDKASYVRRVAVLGCAKMHNLHGDSEVDGALVNELYSLLRDQDPIVVVNCL
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB5 RSLEEILKQEGGVVINKPIAHHLLNRMSKLDQWGQAEVLNFLLRYQPRSEEELFDILNLL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RSLEEILKQEGGVVINKPIAHHLLNRMSKLDQWGQAEVLNFLLRYQPRSEEELFDILNLL
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB5 DSFLKSSSPGVVMGATKLFLILAKMFPHVQTDVLVRVKGPLLAACSSESRELCFVALCHV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DSFLKSSSPGVVMGATKLFLILAKMFPHVQTDVLVRVKGPLLAACSSESRELCFVALCHV
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KB5 RQILHSLPGHFSSHYKKFFCSYSEPHYIKLQKVEVLCELVNDENVQQVLEELRGYCTDVS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RQILHSLPGHFSSHYKKFFCSYSEPHYIKLQKVEVLCELVNDENVQQVLEELRGYCTDVS
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KB5 ADFAQAAIFAIGGIARTYTDQCVQILTELLGLRQEHITTVVVQTFRDLVWLCPQCTEAVC
       ::::::::::::::::::::::::::::::::::::::: .                   
XP_016 ADFAQAAIFAIGGIARTYTDQCVQILTELLGLRQEHITTEIQPES               
              370       380       390       400                    

              430       440       450       460       470       480
pF1KB5 QALPGCEENIQDSEGKQALIWLLGVHGERIPNAPYVLEDFVENVKSETFPAVKMELLTAS




739 residues in 1 query   sequences
60827320 residues in 85289 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Thu Nov  3 22:30:05 2016 done: Thu Nov  3 22:30:07 2016
 Total Scan time: 12.100 Total Display time:  0.200

Function used was FASTA [36.3.4 Apr, 2011]
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