Result of FASTA (omim) for pF1KB5281
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KB5281, 272 aa
  1>>>pF1KB5281 272 - 272 aa - 272 aa
Library: /omim/omim.rfq.tfa
  60827320 residues in 85289 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 8.7788+/-0.000268; mu= 2.4569+/- 0.017
 mean_var=222.8349+/-44.393, 0's: 0 Z-trim(126.5): 25  B-trim: 85 in 1/61
 Lambda= 0.085918
 statistics sampled from 52735 (52767) to 52735 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.864), E-opt: 0.2 (0.619), width:  16
 Scan time:  9.830

The best scores are:                                      opt bits E(85289)
NP_620450 (OMIM: 606385) oligodendrocyte transcrip ( 271) 1786 232.7 5.7e-61
XP_005260965 (OMIM: 606386) PREDICTED: oligodendro ( 323)  317 50.6 4.2e-06
NP_005797 (OMIM: 606386) oligodendrocyte transcrip ( 323)  317 50.6 4.2e-06
NP_786923 (OMIM: 609323) oligodendrocyte transcrip ( 272)  310 49.7 6.8e-06
NP_542173 (OMIM: 609331) class E basic helix-loop- ( 241)  296 47.9 2.1e-05
NP_689627 (OMIM: 613483) class E basic helix-loop- ( 381)  291 47.5 4.5e-05
NP_803238 (OMIM: 608606) class A basic helix-loop- ( 189)  227 39.3  0.0065


>>NP_620450 (OMIM: 606385) oligodendrocyte transcription  (271 aa)
 initn: 1522 init1: 1522 opt: 1786  Z-score: 1215.6  bits: 232.7 E(85289): 5.7e-61
Smith-Waterman score: 1786; 99.6% identity (99.6% similar) in 272 aa overlap (1-272:1-271)

               10        20        30        40        50        60
pF1KB5 MYYAVSQARVNAVPGTMLRPQRPGDLQLGASLYELVGYRQPPSSSSSSSTSSTSSTSSSS
       :::::::::::::::::::::::::::::::::::::::::::::::: :::::::::::
NP_620 MYYAVSQARVNAVPGTMLRPQRPGDLQLGASLYELVGYRQPPSSSSSS-TSSTSSTSSSS
               10        20        30        40         50         

               70        80        90       100       110       120
pF1KB5 TTAPLLPKAAREKPEAPAEPPGPGPGSGAHPGGSARPDAKEEQQQQLRRKINSRERKRMQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_620 TTAPLLPKAAREKPEAPAEPPGPGPGSGAHPGGSARPDAKEEQQQQLRRKINSRERKRMQ
      60        70        80        90       100       110         

              130       140       150       160       170       180
pF1KB5 DLNLAMDALREVILPYSAAHCQGAPGRKLSKIATLLLARNYILLLGSSLQELRRALGEGA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_620 DLNLAMDALREVILPYSAAHCQGAPGRKLSKIATLLLARNYILLLGSSLQELRRALGEGA
     120       130       140       150       160       170         

              190       200       210       220       230       240
pF1KB5 GPAAPRLLLAGLPLLAAAPGSVLLAPGAVGPPDALRPAKYLSLALDEPPCGQFALPGGGA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_620 GPAAPRLLLAGLPLLAAAPGSVLLAPGAVGPPDALRPAKYLSLALDEPPCGQFALPGGGA
     180       190       200       210       220       230         

              250       260       270  
pF1KB5 GGPGLCTCAVCKFPHLVPASLGLAAVQAQFSK
       ::::::::::::::::::::::::::::::::
NP_620 GGPGLCTCAVCKFPHLVPASLGLAAVQAQFSK
     240       250       260       270 

>>XP_005260965 (OMIM: 606386) PREDICTED: oligodendrocyte  (323 aa)
 initn: 385 init1: 159 opt: 317  Z-score: 230.5  bits: 50.6 E(85289): 4.2e-06
Smith-Waterman score: 355; 36.6% identity (51.0% similar) in 290 aa overlap (42-254:23-301)

              20        30        40        50        60        70 
pF1KB5 AVPGTMLRPQRPGDLQLGASLYELVGYRQPPSSSSSSSTSSTSSTSSSSTTAPLLPKAAR
                                     :. :..:: :. .. . ::.:    :    
XP_005         MDSDASLVSSRPSSPEPDDLFLPARSKGSSGSAFTGGTVSSSTPSDCP----
                       10        20        30        40            

              80        90                               100       
pF1KB5 EKPEAPAEPPGPGPGSGAHPG------------------------GSARPDAK---EEQQ
         ::  ::  :   ..:::::                        .:.. : :   : . 
XP_005 --PELSAELRGAMGSAGAHPGDKLGGSGFKSSSSSTSSSTSSAAASSTKKDKKQMTEPEL
         50        60        70        80        90       100      

          110       120       130       140       150       160    
pF1KB5 QQLRRKINSRERKRMQDLNLAMDALREVILPYSAAHCQGAPGRKLSKIATLLLARNYILL
       :::: ::::::::::.:::.:::.:::: .::  ::  :   :::::::::::::::::.
XP_005 QQLRLKINSRERKRMHDLNIAMDGLREV-MPY--AH--GPSVRKLSKIATLLLARNYILM
        110       120       130            140       150       160 

          170            180         190         200               
pF1KB5 LGSSLQELRRAL-----GEGAG--PAAPRLLLAGLPLLAAA--PGSV------------L
       : .::.:..: .     :. ::  :.:   :  . :: ::.  :...            .
XP_005 LTNSLEEMKRLVSEIYGGHHAGFHPSACGGLAHSAPLPAATAHPAAAAHAAHHPAVHHPI
             170       180       190       200       210       220 

           210       220                 230               240     
pF1KB5 LAPGAVGPPDALRPAKYLSLALD----------EPPCGQFALP--------GGGAGGPGL
       : :.:..   :   :   : .:           .:: : .  :        :::.:: : 
XP_005 LPPAAAAAAAAAAAAAVSSASLPGSGLPSVGSIRPPHGLLKSPSAAAAAPLGGGGGGSGA
             230       240       250       260       270       280 

                    250       260       270      
pF1KB5 -----------CTCAVCKFPHLVPASLGLAAVQAQFSK    
                  : :..:. :                      
XP_005 SGGFQHWGGMPCPCSMCQVPPPHHHVSAMGAGSLPRLTSDAK
             290       300       310       320   

>>NP_005797 (OMIM: 606386) oligodendrocyte transcription  (323 aa)
 initn: 385 init1: 159 opt: 317  Z-score: 230.5  bits: 50.6 E(85289): 4.2e-06
Smith-Waterman score: 355; 36.6% identity (51.0% similar) in 290 aa overlap (42-254:23-301)

              20        30        40        50        60        70 
pF1KB5 AVPGTMLRPQRPGDLQLGASLYELVGYRQPPSSSSSSSTSSTSSTSSSSTTAPLLPKAAR
                                     :. :..:: :. .. . ::.:    :    
NP_005         MDSDASLVSSRPSSPEPDDLFLPARSKGSSGSAFTGGTVSSSTPSDCP----
                       10        20        30        40            

              80        90                               100       
pF1KB5 EKPEAPAEPPGPGPGSGAHPG------------------------GSARPDAK---EEQQ
         ::  ::  :   ..:::::                        .:.. : :   : . 
NP_005 --PELSAELRGAMGSAGAHPGDKLGGSGFKSSSSSTSSSTSSAAASSTKKDKKQMTEPEL
         50        60        70        80        90       100      

          110       120       130       140       150       160    
pF1KB5 QQLRRKINSRERKRMQDLNLAMDALREVILPYSAAHCQGAPGRKLSKIATLLLARNYILL
       :::: ::::::::::.:::.:::.:::: .::  ::  :   :::::::::::::::::.
NP_005 QQLRLKINSRERKRMHDLNIAMDGLREV-MPY--AH--GPSVRKLSKIATLLLARNYILM
        110       120       130            140       150       160 

          170            180         190         200               
pF1KB5 LGSSLQELRRAL-----GEGAG--PAAPRLLLAGLPLLAAA--PGSV------------L
       : .::.:..: .     :. ::  :.:   :  . :: ::.  :...            .
NP_005 LTNSLEEMKRLVSEIYGGHHAGFHPSACGGLAHSAPLPAATAHPAAAAHAAHHPAVHHPI
             170       180       190       200       210       220 

           210       220                 230               240     
pF1KB5 LAPGAVGPPDALRPAKYLSLALD----------EPPCGQFALP--------GGGAGGPGL
       : :.:..   :   :   : .:           .:: : .  :        :::.:: : 
NP_005 LPPAAAAAAAAAAAAAVSSASLPGSGLPSVGSIRPPHGLLKSPSAAAAAPLGGGGGGSGA
             230       240       250       260       270       280 

                    250       260       270      
pF1KB5 -----------CTCAVCKFPHLVPASLGLAAVQAQFSK    
                  : :..:. :                      
NP_005 SGGFQHWGGMPCPCSMCQVPPPHHHVSAMGAGSLPRLTSDAK
             290       300       310       320   

>>NP_786923 (OMIM: 609323) oligodendrocyte transcription  (272 aa)
 initn: 334 init1: 158 opt: 310  Z-score: 226.8  bits: 49.7 E(85289): 6.8e-06
Smith-Waterman score: 349; 42.3% identity (57.7% similar) in 227 aa overlap (83-272:52-268)

             60        70        80           90        100        
pF1KB5 TSSTSSSSTTAPLLPKAAREKPEAPAEPPGPGPG---SGAHPGG-SARPDAK----EEQQ
                                     :: .   .::. .: :..   :    :.. 
NP_786 LRDHHHRHHHHQESRLNSVSSTQGDMMQKMPGESLSRAGAKAAGESSKYKIKKQLSEQDL
              30        40        50        60        70        80 

          110       120       130       140       150       160    
pF1KB5 QQLRRKINSRERKRMQDLNLAMDALREVILPYSAAHCQGAPGRKLSKIATLLLARNYILL
       :::: :::.::::::.:::::::.:::: .::  ::  :   :::::::::::::::::.
NP_786 QQLRLKINGRERKRMHDLNLAMDGLREV-MPY--AH--GPSVRKLSKIATLLLARNYILM
              90       100        110           120       130      

          170       180             190               200       210
pF1KB5 LGSSLQELRRALGEGAGPAAPRLLL------AGLPLLAAA---P-----GSVLLAPGAVG
       : :::.:..: .::  :     .        :: :  ::    :     :..: . .: .
NP_786 LTSSLEEMKRLVGEIYGGHHSAFHCGTVGHSAGHPAHAANSVHPVHPILGGALSSGNASS
        140       150       160       170       180       190      

                      220       230           240       250        
pF1KB5 PPDA--------LRPAKYLSLALDEPPCGQFALPGGG----AGGPGLCTCAVCKFP---H
       : .:        .:: . :  : . ::  :.   :.:    :: :  : :..:..:   :
NP_786 PLSAASLPAIGTIRPPHSLLKAPSTPPALQL---GSGFQHWAGLP--CPCTICQMPPPPH
        200       210       220          230         240       250 

         260       270      
pF1KB5 LVPASLGLAAVQAQFSK    
       :   : .  :  .  ::    
NP_786 LSALSTANMARLSAESKDLLK
             260       270  

>>NP_542173 (OMIM: 609331) class E basic helix-loop-heli  (241 aa)
 initn: 290 init1: 141 opt: 296  Z-score: 218.1  bits: 47.9 E(85289): 2.1e-05
Smith-Waterman score: 296; 48.5% identity (70.6% similar) in 136 aa overlap (84-213:100-221)

            60        70        80        90       100       110   
pF1KB5 SSTSSSSTTAPLLPKAAREKPEAPAEPPGPGPGSGAHPGGSARPDAKEEQQQQLRRKINS
                                     ::::.:   :  ::    ..:..:: .::.
NP_542 APRAPAQAAESSGEQSGDEDDAFEQRRRRRGPGSAAD--GRRRP----REQRSLRLSINA
      70        80        90       100         110           120   

           120       130       140       150       160       170   
pF1KB5 RERKRMQDLNLAMDALREVILPYSAAHCQGAPGRKLSKIATLLLARNYILLLGSSLQELR
       :::.::.::: :.:.:: :: ::  ::  ..  ::::::::::::.::::. ...:.:.:
NP_542 RERRRMHDLNDALDGLRAVI-PY--AHSPSV--RKLSKIATLLLAKNYILMQAQALDEMR
           130       140          150         160       170        

              180       190       200         210        220       
pF1KB5 RA---LGEGAGPAAPRLLLAGLPLLAAAPGSV--LLAPGAVGP-PDALRPAKYLSLALDE
       :    :..: : :::   . . ::   . ..:  . : .:.:: ::              
NP_542 RLVAFLNQGQGLAAP---VNAAPLTPFGQATVCPFSAGAALGPCPDKCAAFSGTPSALCK
      180       190          200       210       220       230     

       230       240       250       260       270  
pF1KB5 PPCGQFALPGGGAGGPGLCTCAVCKFPHLVPASLGLAAVQAQFSK
                                                    
NP_542 HCHEKP                                       
         240                                        

>>NP_689627 (OMIM: 613483) class E basic helix-loop-heli  (381 aa)
 initn: 274 init1: 164 opt: 291  Z-score: 212.1  bits: 47.5 E(85289): 4.5e-05
Smith-Waterman score: 293; 43.0% identity (65.6% similar) in 151 aa overlap (82-229:218-355)

              60        70        80        90       100       110 
pF1KB5 STSSTSSSSTTAPLLPKAAREKPEAPAEPPGPGPGSGAHPGGSARPDAKEEQQQQLRRKI
                                     : : :::.  ..:.  . : ..:. :: .:
NP_689 HLHGGASVPPGGLGGGGGGGSSSGSSGGGGGSGSGSGGSSSSSSSSSKKSKEQKALRLNI
       190       200       210       220       230       240       

             120       130       140       150       160       170 
pF1KB5 NSRERKRMQDLNLAMDALREVILPYSAAHCQGAPGRKLSKIATLLLARNYILLLGSSLQE
       :.:::.::.::: :.: :: :: ::  ::  ..  ::::::::::::.::::. ...:.:
NP_689 NARERRRMHDLNDALDELRAVI-PY--AHSPSV--RKLSKIATLLLAKNYILMQAQALEE
       250       260        270           280       290       300  

                180       190       200       210       220        
pF1KB5 LRRA---LGEGAGPAAPRLLLAGLPLLAAAPGSVLLAPGAVGPPDALRPAKYLSLALDEP
       .::    :..: . .:     :.::  ::: ...     :.:   : . :    ..   :
NP_689 MRRLVAYLNQGQAISA-----ASLPSSAAAAAAAAALHPALG---AYEQAAGYPFSAGLP
            310            320       330          340       350    

      230       240       250       260       270  
pF1KB5 PCGQFALPGGGAGGPGLCTCAVCKFPHLVPASLGLAAVQAQFSK
       :                                           
NP_689 PAASCPEKCALFNSVSSSLCKQCTEKP                 
          360       370       380                  

>>NP_803238 (OMIM: 608606) class A basic helix-loop-heli  (189 aa)
 initn: 236 init1:  88 opt: 227  Z-score: 173.3  bits: 39.3 E(85289): 0.0065
Smith-Waterman score: 227; 36.7% identity (59.9% similar) in 147 aa overlap (39-182:10-147)

       10        20        30        40        50        60        
pF1KB5 RVNAVPGTMLRPQRPGDLQLGASLYELVGYRQPPSSSSSSSTSSTSSTSSSSTTAPLLPK
                                     :. : ... .. .  .  .:  . .:   :
NP_803                      MKTKNRPPRRRAPVQDTEATPGEGTPDGSLPNPGPEPAK
                                    10        20        30         

       70        80        90       100       110       120        
pF1KB5 AAREKPEAPAEPPGPGPGSGAHPGGSARPDAKEEQQQQLRRKINSRERKRMQDLNLAMDA
       . : .: : :   .:: :   .:: :. : ...... : : . : :::.::. :: :..:
NP_803 GLRSRP-ARAAARAPGEGRRRRPGPSG-PGGRRDSSIQRRLESNERERQRMHKLNNAFQA
      40         50        60         70        80        90       

      130       140       150       160       170          180     
pF1KB5 LREVILPYSAAHCQGAPGRKLSKIATLLLARNYILLLGSSLQELR--RALG-EGAGPAAP
       ::::: :.  :       .::::: :: ::.:::  : ...  .   :  : :: ::   
NP_803 LREVI-PHVRAD------KKLSKIETLTLAKNYIKSLTATILTMSSSRLPGLEGPGPKLY
       100              110       120       130       140       150

         190       200       210       220       230       240     
pF1KB5 RLLLAGLPLLAAAPGSVLLAPGAVGPPDALRPAKYLSLALDEPPCGQFALPGGGAGGPGL
                                                                   
NP_803 QHYQQQQQVAGGALGATEAQPQGHLQRYSTQIHSFREGT                     
              160       170       180                              




272 residues in 1 query   sequences
60827320 residues in 85289 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Thu Nov  3 22:25:58 2016 done: Thu Nov  3 22:25:59 2016
 Total Scan time:  9.830 Total Display time: -0.010

Function used was FASTA [36.3.4 Apr, 2011]
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