Result of FASTA (omim) for pF1KB5025
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KB5025, 239 aa
  1>>>pF1KB5025 239 - 239 aa - 239 aa
Library: /omim/omim.rfq.tfa
  60827320 residues in 85289 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 7.1522+/-0.000326; mu= 9.8141+/- 0.021
 mean_var=168.3649+/-33.597, 0's: 0 Z-trim(122.5): 42  B-trim: 1401 in 2/56
 Lambda= 0.098844
 statistics sampled from 40709 (40759) to 40709 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.781), E-opt: 0.2 (0.478), width:  16
 Scan time:  7.890

The best scores are:                                      opt bits E(85289)
NP_079478 (OMIM: 611617) EF-hand domain-containing ( 239) 1543 230.7 1.7e-60
NP_077305 (OMIM: 616450) EF-hand domain-containing ( 240)  972 149.3 5.5e-36
NP_001230181 (OMIM: 611617) EF-hand domain-contain ( 143)  867 134.1 1.2e-31
XP_011510226 (OMIM: 611617) PREDICTED: EF-hand dom ( 127)  789 123.0 2.5e-28
NP_001295324 (OMIM: 611617) EF-hand domain-contain ( 127)  789 123.0 2.5e-28
XP_005246057 (OMIM: 616450) PREDICTED: EF-hand dom ( 195)  587 94.3 1.6e-19


>>NP_079478 (OMIM: 611617) EF-hand domain-containing pro  (239 aa)
 initn: 1543 init1: 1543 opt: 1543  Z-score: 1207.2  bits: 230.7 E(85289): 1.7e-60
Smith-Waterman score: 1543; 100.0% identity (100.0% similar) in 239 aa overlap (1-239:1-239)

               10        20        30        40        50        60
pF1KB5 MASEELACKLERRLRREEAEESGPQLAPLGAPAPEPKPEPEPPARAPTASADAELSAQLS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_079 MASEELACKLERRLRREEAEESGPQLAPLGAPAPEPKPEPEPPARAPTASADAELSAQLS
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB5 RRLDINEGAARPRRCRVFNPYTEFPEFSRRLIKDLESMFKLYDAGRDGFIDLMELKLMME
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_079 RRLDINEGAARPRRCRVFNPYTEFPEFSRRLIKDLESMFKLYDAGRDGFIDLMELKLMME
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB5 KLGAPQTHLGLKSMIKEVDEDFDGKLSFREFLLIFHKAAAGELQEDSGLMALAKLSEIDV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_079 KLGAPQTHLGLKSMIKEVDEDFDGKLSFREFLLIFHKAAAGELQEDSGLMALAKLSEIDV
              130       140       150       160       170       180

              190       200       210       220       230         
pF1KB5 ALEGVKGAKNFFEAKVQALSSASKFEAELKAEQDERKREEEERRLRQAAFQKLKANFNT
       :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_079 ALEGVKGAKNFFEAKVQALSSASKFEAELKAEQDERKREEEERRLRQAAFQKLKANFNT
              190       200       210       220       230         

>>NP_077305 (OMIM: 616450) EF-hand domain-containing pro  (240 aa)
 initn: 1025 init1: 834 opt: 972  Z-score: 767.1  bits: 149.3 E(85289): 5.5e-36
Smith-Waterman score: 972; 66.4% identity (83.8% similar) in 241 aa overlap (1-237:1-239)

               10        20          30        40        50        
pF1KB5 MASEELACKLERRLRREEAEESG--PQLAPLGAPAPEPKPEPEPPARAPTASADAELSAQ
       ::..::: :: :::. : .: .:  :.   :.. :      :.  :.:  .::: ::::.
NP_077 MATDELATKLSRRLQME-GEGGGETPEQPGLNGAAAAAAGAPDEAAEA-LGSADCELSAK
               10         20        30        40         50        

       60        70          80        90       100       110      
pF1KB5 LSRRLDINEGAARPRRC--RVFNPYTEFPEFSRRLIKDLESMFKLYDAGRDGFIDLMELK
       : :: :.:.: ..:.    ::::::::: ::::. :::.:.::: :::::::::::::::
NP_077 LLRRADLNQGIGEPQSPSRRVFNPYTEFKEFSRKQIKDMEKMFKQYDAGRDGFIDLMELK
       60        70        80        90       100       110        

        120       130       140       150       160       170      
pF1KB5 LMMEKLGAPQTHLGLKSMIKEVDEDFDGKLSFREFLLIFHKAAAGELQEDSGLMALAKLS
       ::::::::::::::::.::::::::::.:::::::::::.::::::::::::: .::.::
NP_077 LMMEKLGAPQTHLGLKNMIKEVDEDFDSKLSFREFLLIFRKAAAGELQEDSGLCVLARLS
      120       130       140       150       160       170        

        180       190       200       210       220       230      
pF1KB5 EIDVALEGVKGAKNFFEAKVQALSSASKFEAELKAEQDERKREEEERRLRQAAFQKLKAN
       ::::. :::::::.::::::::.. .:.:: :.::::.:::.. :: . :.:::..:...
NP_077 EIDVSSEGVKGAKSFFEAKVQAINVSSRFEEEIKAEQEERKKQAEEMKQRKAAFKELQST
      180       190       200       210       220       230        

          
pF1KB5 FNT
       :  
NP_077 FK 
      240 

>>NP_001230181 (OMIM: 611617) EF-hand domain-containing   (143 aa)
 initn: 867 init1: 867 opt: 867  Z-score: 689.0  bits: 134.1 E(85289): 1.2e-31
Smith-Waterman score: 867; 100.0% identity (100.0% similar) in 138 aa overlap (102-239:6-143)

              80        90       100       110       120       130 
pF1KB5 PRRCRVFNPYTEFPEFSRRLIKDLESMFKLYDAGRDGFIDLMELKLMMEKLGAPQTHLGL
                                     ::::::::::::::::::::::::::::::
NP_001                          MGELQYDAGRDGFIDLMELKLMMEKLGAPQTHLGL
                                        10        20        30     

             140       150       160       170       180       190 
pF1KB5 KSMIKEVDEDFDGKLSFREFLLIFHKAAAGELQEDSGLMALAKLSEIDVALEGVKGAKNF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KSMIKEVDEDFDGKLSFREFLLIFHKAAAGELQEDSGLMALAKLSEIDVALEGVKGAKNF
          40        50        60        70        80        90     

             200       210       220       230         
pF1KB5 FEAKVQALSSASKFEAELKAEQDERKREEEERRLRQAAFQKLKANFNT
       ::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FEAKVQALSSASKFEAELKAEQDERKREEEERRLRQAAFQKLKANFNT
         100       110       120       130       140   

>>XP_011510226 (OMIM: 611617) PREDICTED: EF-hand domain-  (127 aa)
 initn: 789 init1: 789 opt: 789  Z-score: 629.6  bits: 123.0 E(85289): 2.5e-28
Smith-Waterman score: 789; 100.0% identity (100.0% similar) in 127 aa overlap (113-239:1-127)

             90       100       110       120       130       140  
pF1KB5 EFPEFSRRLIKDLESMFKLYDAGRDGFIDLMELKLMMEKLGAPQTHLGLKSMIKEVDEDF
                                     ::::::::::::::::::::::::::::::
XP_011                               MELKLMMEKLGAPQTHLGLKSMIKEVDEDF
                                             10        20        30

            150       160       170       180       190       200  
pF1KB5 DGKLSFREFLLIFHKAAAGELQEDSGLMALAKLSEIDVALEGVKGAKNFFEAKVQALSSA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DGKLSFREFLLIFHKAAAGELQEDSGLMALAKLSEIDVALEGVKGAKNFFEAKVQALSSA
               40        50        60        70        80        90

            210       220       230         
pF1KB5 SKFEAELKAEQDERKREEEERRLRQAAFQKLKANFNT
       :::::::::::::::::::::::::::::::::::::
XP_011 SKFEAELKAEQDERKREEEERRLRQAAFQKLKANFNT
              100       110       120       

>>NP_001295324 (OMIM: 611617) EF-hand domain-containing   (127 aa)
 initn: 789 init1: 789 opt: 789  Z-score: 629.6  bits: 123.0 E(85289): 2.5e-28
Smith-Waterman score: 789; 100.0% identity (100.0% similar) in 127 aa overlap (113-239:1-127)

             90       100       110       120       130       140  
pF1KB5 EFPEFSRRLIKDLESMFKLYDAGRDGFIDLMELKLMMEKLGAPQTHLGLKSMIKEVDEDF
                                     ::::::::::::::::::::::::::::::
NP_001                               MELKLMMEKLGAPQTHLGLKSMIKEVDEDF
                                             10        20        30

            150       160       170       180       190       200  
pF1KB5 DGKLSFREFLLIFHKAAAGELQEDSGLMALAKLSEIDVALEGVKGAKNFFEAKVQALSSA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DGKLSFREFLLIFHKAAAGELQEDSGLMALAKLSEIDVALEGVKGAKNFFEAKVQALSSA
               40        50        60        70        80        90

            210       220       230         
pF1KB5 SKFEAELKAEQDERKREEEERRLRQAAFQKLKANFNT
       :::::::::::::::::::::::::::::::::::::
NP_001 SKFEAELKAEQDERKREEEERRLRQAAFQKLKANFNT
              100       110       120       

>>XP_005246057 (OMIM: 616450) PREDICTED: EF-hand domain-  (195 aa)
 initn: 757 init1: 449 opt: 587  Z-score: 471.5  bits: 94.3 E(85289): 1.6e-19
Smith-Waterman score: 641; 50.6% identity (66.0% similar) in 241 aa overlap (1-237:1-194)

               10        20          30        40        50        
pF1KB5 MASEELACKLERRLRREEAEESG--PQLAPLGAPAPEPKPEPEPPARAPTASADAELSAQ
       ::..::: :: :::. : .: .:  :.   :.. :      :.  :.:  .::: ::::.
XP_005 MATDELATKLSRRLQME-GEGGGETPEQPGLNGAAAAAAGAPDEAAEA-LGSADCELSAK
               10         20        30        40         50        

       60        70          80        90       100       110      
pF1KB5 LSRRLDINEGAARPRRC--RVFNPYTEFPEFSRRLIKDLESMFKLYDAGRDGFIDLMELK
       : :: :.:.: ..:.    ::::::::: ::::. :::.:.::: :::::::::::::::
XP_005 LLRRADLNQGIGEPQSPSRRVFNPYTEFKEFSRKQIKDMEKMFKQYDAGRDGFIDLMELK
       60        70        80        90       100       110        

        120       130       140       150       160       170      
pF1KB5 LMMEKLGAPQTHLGLKSMIKEVDEDFDGKLSFREFLLIFHKAAAGELQEDSGLMALAKLS
       ::::::::::::::::.::::::::::.::::::                          
XP_005 LMMEKLGAPQTHLGLKNMIKEVDEDFDSKLSFRE--------------------------
      120       130       140       150                            

        180       190       200       210       220       230      
pF1KB5 EIDVALEGVKGAKNFFEAKVQALSSASKFEAELKAEQDERKREEEERRLRQAAFQKLKAN
                          :::.. .:.:: :.::::.:::.. :: . :.:::..:...
XP_005 -------------------VQAINVSSRFEEEIKAEQEERKKQAEEMKQRKAAFKELQST
                               160       170       180       190   

          
pF1KB5 FNT
       :  
XP_005 FK 
          




239 residues in 1 query   sequences
60827320 residues in 85289 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Thu Nov  3 22:13:50 2016 done: Thu Nov  3 22:13:51 2016
 Total Scan time:  7.890 Total Display time: -0.020

Function used was FASTA [36.3.4 Apr, 2011]
Inquiries or Suggestions ?
Send a message to flexiclone AT kazusagt.com