Result of FASTA (omim) for pF1KB4051
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KB4051, 341 aa
  1>>>pF1KB4051 341 - 341 aa - 341 aa
Library: /omim/omim.rfq.tfa
  60827320 residues in 85289 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 15.0509+/-0.000659; mu= -32.6598+/- 0.039
 mean_var=937.3871+/-217.234, 0's: 0 Z-trim(112.5): 64  B-trim: 0 in 0/54
 Lambda= 0.041890
 statistics sampled from 21470 (21478) to 21470 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.607), E-opt: 0.2 (0.252), width:  16
 Scan time:  7.060

The best scores are:                                      opt bits E(85289)
NP_001230462 (OMIM: 610785) serine/threonine-prote ( 341) 2242 151.8   2e-36
NP_001230461 (OMIM: 610785) serine/threonine-prote ( 341) 2242 151.8   2e-36
NP_690048 (OMIM: 610785) serine/threonine-protein  ( 341) 2242 151.8   2e-36
XP_005245800 (OMIM: 610785) PREDICTED: serine/thre ( 341) 2242 151.8   2e-36
XP_011539094 (OMIM: 610785) PREDICTED: serine/thre ( 257) 1642 115.4 1.4e-25
XP_006710444 (OMIM: 610785) PREDICTED: serine/thre ( 263) 1622 114.2 3.2e-25
NP_543026 (OMIM: 609370) serine/threonine-protein  ( 534) 1532 109.1 2.2e-23
XP_011527476 (OMIM: 609370) PREDICTED: serine/thre ( 430)  478 45.3 0.00028


>>NP_001230462 (OMIM: 610785) serine/threonine-protein k  (341 aa)
 initn: 2242 init1: 2242 opt: 2242  Z-score: 775.0  bits: 151.8 E(85289): 2e-36
Smith-Waterman score: 2242; 100.0% identity (100.0% similar) in 341 aa overlap (1-341:1-341)

               10        20        30        40        50        60
pF1KB4 MVSSQPKYDLIREVGRGSYGVVYEAVIRKTSARVAVKKIRCHAPENVELALREFWALSSI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MVSSQPKYDLIREVGRGSYGVVYEAVIRKTSARVAVKKIRCHAPENVELALREFWALSSI
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB4 KSQHPNVIHLEECILQKDGMVQKMSHGSNSSLYLQLVETSLKGEIAFDPRSAYYLWFVMD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KSQHPNVIHLEECILQKDGMVQKMSHGSNSSLYLQLVETSLKGEIAFDPRSAYYLWFVMD
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB4 FCDGGDMNEYLLSRKPNRKTNTSFMLQLSSALAFLHKNQIIHRDLKPDNILISQTRLDTS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FCDGGDMNEYLLSRKPNRKTNTSFMLQLSSALAFLHKNQIIHRDLKPDNILISQTRLDTS
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB4 DLEPTLKVADFGLSKVCSASGQNPEEPVSVNKCFLSTACGTDFYMAPEVWEGHYTAKADI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DLEPTLKVADFGLSKVCSASGQNPEEPVSVNKCFLSTACGTDFYMAPEVWEGHYTAKADI
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB4 FALGIIIWAMLERITFIDTETKKELLGSYVKQGTEIVPVGEALLENPKMELLIPVKKKSM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FALGIIIWAMLERITFIDTETKKELLGSYVKQGTEIVPVGEALLENPKMELLIPVKKKSM
              250       260       270       280       290       300

              310       320       330       340 
pF1KB4 NGRMKQLIKEMLAANPQDRPDAFELELRLVQIAFKDSSWET
       :::::::::::::::::::::::::::::::::::::::::
NP_001 NGRMKQLIKEMLAANPQDRPDAFELELRLVQIAFKDSSWET
              310       320       330       340 

>>NP_001230461 (OMIM: 610785) serine/threonine-protein k  (341 aa)
 initn: 2242 init1: 2242 opt: 2242  Z-score: 775.0  bits: 151.8 E(85289): 2e-36
Smith-Waterman score: 2242; 100.0% identity (100.0% similar) in 341 aa overlap (1-341:1-341)

               10        20        30        40        50        60
pF1KB4 MVSSQPKYDLIREVGRGSYGVVYEAVIRKTSARVAVKKIRCHAPENVELALREFWALSSI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MVSSQPKYDLIREVGRGSYGVVYEAVIRKTSARVAVKKIRCHAPENVELALREFWALSSI
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB4 KSQHPNVIHLEECILQKDGMVQKMSHGSNSSLYLQLVETSLKGEIAFDPRSAYYLWFVMD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KSQHPNVIHLEECILQKDGMVQKMSHGSNSSLYLQLVETSLKGEIAFDPRSAYYLWFVMD
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB4 FCDGGDMNEYLLSRKPNRKTNTSFMLQLSSALAFLHKNQIIHRDLKPDNILISQTRLDTS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FCDGGDMNEYLLSRKPNRKTNTSFMLQLSSALAFLHKNQIIHRDLKPDNILISQTRLDTS
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB4 DLEPTLKVADFGLSKVCSASGQNPEEPVSVNKCFLSTACGTDFYMAPEVWEGHYTAKADI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DLEPTLKVADFGLSKVCSASGQNPEEPVSVNKCFLSTACGTDFYMAPEVWEGHYTAKADI
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB4 FALGIIIWAMLERITFIDTETKKELLGSYVKQGTEIVPVGEALLENPKMELLIPVKKKSM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FALGIIIWAMLERITFIDTETKKELLGSYVKQGTEIVPVGEALLENPKMELLIPVKKKSM
              250       260       270       280       290       300

              310       320       330       340 
pF1KB4 NGRMKQLIKEMLAANPQDRPDAFELELRLVQIAFKDSSWET
       :::::::::::::::::::::::::::::::::::::::::
NP_001 NGRMKQLIKEMLAANPQDRPDAFELELRLVQIAFKDSSWET
              310       320       330       340 

>>NP_690048 (OMIM: 610785) serine/threonine-protein kina  (341 aa)
 initn: 2242 init1: 2242 opt: 2242  Z-score: 775.0  bits: 151.8 E(85289): 2e-36
Smith-Waterman score: 2242; 100.0% identity (100.0% similar) in 341 aa overlap (1-341:1-341)

               10        20        30        40        50        60
pF1KB4 MVSSQPKYDLIREVGRGSYGVVYEAVIRKTSARVAVKKIRCHAPENVELALREFWALSSI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_690 MVSSQPKYDLIREVGRGSYGVVYEAVIRKTSARVAVKKIRCHAPENVELALREFWALSSI
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB4 KSQHPNVIHLEECILQKDGMVQKMSHGSNSSLYLQLVETSLKGEIAFDPRSAYYLWFVMD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_690 KSQHPNVIHLEECILQKDGMVQKMSHGSNSSLYLQLVETSLKGEIAFDPRSAYYLWFVMD
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB4 FCDGGDMNEYLLSRKPNRKTNTSFMLQLSSALAFLHKNQIIHRDLKPDNILISQTRLDTS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_690 FCDGGDMNEYLLSRKPNRKTNTSFMLQLSSALAFLHKNQIIHRDLKPDNILISQTRLDTS
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB4 DLEPTLKVADFGLSKVCSASGQNPEEPVSVNKCFLSTACGTDFYMAPEVWEGHYTAKADI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_690 DLEPTLKVADFGLSKVCSASGQNPEEPVSVNKCFLSTACGTDFYMAPEVWEGHYTAKADI
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB4 FALGIIIWAMLERITFIDTETKKELLGSYVKQGTEIVPVGEALLENPKMELLIPVKKKSM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_690 FALGIIIWAMLERITFIDTETKKELLGSYVKQGTEIVPVGEALLENPKMELLIPVKKKSM
              250       260       270       280       290       300

              310       320       330       340 
pF1KB4 NGRMKQLIKEMLAANPQDRPDAFELELRLVQIAFKDSSWET
       :::::::::::::::::::::::::::::::::::::::::
NP_690 NGRMKQLIKEMLAANPQDRPDAFELELRLVQIAFKDSSWET
              310       320       330       340 

>>XP_005245800 (OMIM: 610785) PREDICTED: serine/threonin  (341 aa)
 initn: 2242 init1: 2242 opt: 2242  Z-score: 775.0  bits: 151.8 E(85289): 2e-36
Smith-Waterman score: 2242; 100.0% identity (100.0% similar) in 341 aa overlap (1-341:1-341)

               10        20        30        40        50        60
pF1KB4 MVSSQPKYDLIREVGRGSYGVVYEAVIRKTSARVAVKKIRCHAPENVELALREFWALSSI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MVSSQPKYDLIREVGRGSYGVVYEAVIRKTSARVAVKKIRCHAPENVELALREFWALSSI
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB4 KSQHPNVIHLEECILQKDGMVQKMSHGSNSSLYLQLVETSLKGEIAFDPRSAYYLWFVMD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 KSQHPNVIHLEECILQKDGMVQKMSHGSNSSLYLQLVETSLKGEIAFDPRSAYYLWFVMD
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB4 FCDGGDMNEYLLSRKPNRKTNTSFMLQLSSALAFLHKNQIIHRDLKPDNILISQTRLDTS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 FCDGGDMNEYLLSRKPNRKTNTSFMLQLSSALAFLHKNQIIHRDLKPDNILISQTRLDTS
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB4 DLEPTLKVADFGLSKVCSASGQNPEEPVSVNKCFLSTACGTDFYMAPEVWEGHYTAKADI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 DLEPTLKVADFGLSKVCSASGQNPEEPVSVNKCFLSTACGTDFYMAPEVWEGHYTAKADI
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB4 FALGIIIWAMLERITFIDTETKKELLGSYVKQGTEIVPVGEALLENPKMELLIPVKKKSM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 FALGIIIWAMLERITFIDTETKKELLGSYVKQGTEIVPVGEALLENPKMELLIPVKKKSM
              250       260       270       280       290       300

              310       320       330       340 
pF1KB4 NGRMKQLIKEMLAANPQDRPDAFELELRLVQIAFKDSSWET
       :::::::::::::::::::::::::::::::::::::::::
XP_005 NGRMKQLIKEMLAANPQDRPDAFELELRLVQIAFKDSSWET
              310       320       330       340 

>>XP_011539094 (OMIM: 610785) PREDICTED: serine/threonin  (257 aa)
 initn: 1642 init1: 1642 opt: 1642  Z-score: 580.4  bits: 115.4 E(85289): 1.4e-25
Smith-Waterman score: 1642; 97.6% identity (99.2% similar) in 255 aa overlap (87-341:3-257)

         60        70        80        90       100       110      
pF1KB4 LSSIKSQHPNVIHLEECILQKDGMVQKMSHGSNSSLYLQLVETSLKGEIAFDPRSAYYLW
                                     : ..:.: .:::::::::::::::::::::
XP_011                             MRGRSGSVYPELVETSLKGEIAFDPRSAYYLW
                                           10        20        30  

        120       130       140       150       160       170      
pF1KB4 FVMDFCDGGDMNEYLLSRKPNRKTNTSFMLQLSSALAFLHKNQIIHRDLKPDNILISQTR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FVMDFCDGGDMNEYLLSRKPNRKTNTSFMLQLSSALAFLHKNQIIHRDLKPDNILISQTR
             40        50        60        70        80        90  

        180       190       200       210       220       230      
pF1KB4 LDTSDLEPTLKVADFGLSKVCSASGQNPEEPVSVNKCFLSTACGTDFYMAPEVWEGHYTA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LDTSDLEPTLKVADFGLSKVCSASGQNPEEPVSVNKCFLSTACGTDFYMAPEVWEGHYTA
            100       110       120       130       140       150  

        240       250       260       270       280       290      
pF1KB4 KADIFALGIIIWAMLERITFIDTETKKELLGSYVKQGTEIVPVGEALLENPKMELLIPVK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KADIFALGIIIWAMLERITFIDTETKKELLGSYVKQGTEIVPVGEALLENPKMELLIPVK
            160       170       180       190       200       210  

        300       310       320       330       340 
pF1KB4 KKSMNGRMKQLIKEMLAANPQDRPDAFELELRLVQIAFKDSSWET
       :::::::::::::::::::::::::::::::::::::::::::::
XP_011 KKSMNGRMKQLIKEMLAANPQDRPDAFELELRLVQIAFKDSSWET
            220       230       240       250       

>>XP_006710444 (OMIM: 610785) PREDICTED: serine/threonin  (263 aa)
 initn: 1622 init1: 1622 opt: 1622  Z-score: 573.8  bits: 114.2 E(85289): 3.2e-25
Smith-Waterman score: 1622; 100.0% identity (100.0% similar) in 246 aa overlap (96-341:18-263)

          70        80        90       100       110       120     
pF1KB4 NVIHLEECILQKDGMVQKMSHGSNSSLYLQLVETSLKGEIAFDPRSAYYLWFVMDFCDGG
                                     ::::::::::::::::::::::::::::::
XP_006              MHRAFHPSEPRTPARSSLVETSLKGEIAFDPRSAYYLWFVMDFCDGG
                            10        20        30        40       

         130       140       150       160       170       180     
pF1KB4 DMNEYLLSRKPNRKTNTSFMLQLSSALAFLHKNQIIHRDLKPDNILISQTRLDTSDLEPT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 DMNEYLLSRKPNRKTNTSFMLQLSSALAFLHKNQIIHRDLKPDNILISQTRLDTSDLEPT
        50        60        70        80        90       100       

         190       200       210       220       230       240     
pF1KB4 LKVADFGLSKVCSASGQNPEEPVSVNKCFLSTACGTDFYMAPEVWEGHYTAKADIFALGI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 LKVADFGLSKVCSASGQNPEEPVSVNKCFLSTACGTDFYMAPEVWEGHYTAKADIFALGI
       110       120       130       140       150       160       

         250       260       270       280       290       300     
pF1KB4 IIWAMLERITFIDTETKKELLGSYVKQGTEIVPVGEALLENPKMELLIPVKKKSMNGRMK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 IIWAMLERITFIDTETKKELLGSYVKQGTEIVPVGEALLENPKMELLIPVKKKSMNGRMK
       170       180       190       200       210       220       

         310       320       330       340 
pF1KB4 QLIKEMLAANPQDRPDAFELELRLVQIAFKDSSWET
       ::::::::::::::::::::::::::::::::::::
XP_006 QLIKEMLAANPQDRPDAFELELRLVQIAFKDSSWET
       230       240       250       260   

>>NP_543026 (OMIM: 609370) serine/threonine-protein kina  (534 aa)
 initn: 1491 init1: 527 opt: 1532  Z-score: 540.9  bits: 109.1 E(85289): 2.2e-23
Smith-Waterman score: 1532; 69.3% identity (87.0% similar) in 339 aa overlap (3-332:197-530)

                                           10        20        30  
pF1KB4                             MVSSQPKYDLIREVGRGSYGVVYEAVIRKTSA
                                     :..:.:.:. :.::::::::::::  ...:
NP_543 AAAARAMDPVAAEAPGEAFLARRRPEGGGGSARPRYSLLAEIGRGSYGVVYEAVAGRSGA
        170       180       190       200       210       220      

             40        50        60        70        80        90  
pF1KB4 RVAVKKIRCHAPENVELALREFWALSSIKSQHPNVIHLEECILQKDGMVQKMSHGSNSS-
       ::::::::: ::::::::: :::::.:.: .: ::...:::.::..:..:.::::..:: 
NP_543 RVAVKKIRCDAPENVELALAEFWALTSLKRRHQNVVQFEECVLQRNGLAQRMSHGNKSSQ
        230       240       250       260       270       280      

             100        110       120       130       140       150
pF1KB4 LYLQLVETSLKGE-IAFDPRSAYYLWFVMDFCDGGDMNEYLLSRKPNRKTNTSFMLQLSS
       :::.::::::::: :    .   ::::::.::.:::.:.:.:::.:.  :: ::::::.:
NP_543 LYLRLVETSLKGERILGYAEEPCYLWFVMEFCEGGDLNQYVLSRRPDPATNKSFMLQLTS
        290       300       310       320       330       340      

              160       170       180       190             200    
pF1KB4 ALAFLHKNQIIHRDLKPDNILISQTRLDTSDLEPTLKVADFGLSKVCSA------SGQNP
       :.::::::.:.:::::::::::.. :  :    : ::::::::::::..       :.. 
NP_543 AIAFLHKNHIVHRDLKPDNILITE-RSGT----PILKVADFGLSKVCAGLAPRGKEGNQD
        350       360       370            380       390       400 

          210       220       230       240       250       260    
pF1KB4 EEPVSVNKCFLSTACGTDFYMAPEVWEGHYTAKADIFALGIIIWAMLERITFIDTETKKE
       .. :.::: .::.:::.:::::::::::::::::::::::::::::.:::::::.:::::
NP_543 NKNVNVNKYWLSSACGSDFYMAPEVWEGHYTAKADIFALGIIIWAMIERITFIDSETKKE
             410       420       430       440       450       460 

          270       280       290        300       310       320   
pF1KB4 LLGSYVKQGTEIVPVGEALLENPKMELLIPVKKK-SMNGRMKQLIKEMLAANPQDRPDAF
       :::.:.::::::::::::::::::::: :: :.. ::.  .:::.:.:::::::::::::
NP_543 LLGTYIKQGTEIVPVGEALLENPKMELHIPQKRRTSMSEGIKQLLKDMLAANPQDRPDAF
             470       480       490       500       510       520 

           330       340 
pF1KB4 ELELRLVQIAFKDSSWET
       ::: :. :.         
NP_543 ELETRMDQVTCAA     
             530         

>>XP_011527476 (OMIM: 609370) PREDICTED: serine/threonin  (430 aa)
 initn: 448 init1: 426 opt: 478  Z-score: 197.7  bits: 45.3 E(85289): 0.00028
Smith-Waterman score: 478; 68.6% identity (92.2% similar) in 102 aa overlap (3-103:293-394)

                                           10        20        30  
pF1KB4                             MVSSQPKYDLIREVGRGSYGVVYEAVIRKTSA
                                     :..:.:.:. :.::::::::::::  ...:
XP_011 AAAARAMDPVAAEAPGEAFLARRRPEGGGGSARPRYSLLAEIGRGSYGVVYEAVAGRSGA
            270       280       290       300       310       320  

             40        50        60        70        80        90  
pF1KB4 RVAVKKIRCHAPENVELALREFWALSSIKSQHPNVIHLEECILQKDGMVQKMSHGSNSS-
       ::::::::: ::::::::: :::::.:.: .: ::...:::.::..:..:.::::..:: 
XP_011 RVAVKKIRCDAPENVELALAEFWALTSLKRRHQNVVQFEECVLQRNGLAQRMSHGNKSSQ
            330       340       350       360       370       380  

             100       110       120       130       140       150 
pF1KB4 LYLQLVETSLKGEIAFDPRSAYYLWFVMDFCDGGDMNEYLLSRKPNRKTNTSFMLQLSSA
       :::.::::::::                                                
XP_011 LYLRLVETSLKGRFLGTHSLTTSPPEDGRGYRWWPGRLAISRQLDPAM            
            390       400       410       420       430            




341 residues in 1 query   sequences
60827320 residues in 85289 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Thu Nov  3 21:22:55 2016 done: Thu Nov  3 21:22:56 2016
 Total Scan time:  7.060 Total Display time:  0.020

Function used was FASTA [36.3.4 Apr, 2011]
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