Result of FASTA (omim) for pF1KB3232
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KB3232, 713 aa
  1>>>pF1KB3232 713 - 713 aa - 713 aa
Library: /omim/omim.rfq.tfa
  60827320 residues in 85289 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 7.9421+/-0.000521; mu= 6.9372+/- 0.032
 mean_var=301.8341+/-65.099, 0's: 0 Z-trim(115.9): 306  B-trim: 33 in 1/58
 Lambda= 0.073823
 statistics sampled from 26247 (26711) to 26247 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.665), E-opt: 0.2 (0.313), width:  16
 Scan time: 10.310

The best scores are:                                      opt bits E(85289)
XP_011507368 (OMIM: 605492) PREDICTED: leucine-ric ( 713) 4794 525.7 2.4e-148
NP_006329 (OMIM: 605492) leucine-rich repeat neuro ( 713) 4794 525.7 2.4e-148
XP_005244884 (OMIM: 605492) PREDICTED: leucine-ric ( 713) 4794 525.7 2.4e-148
NP_963924 (OMIM: 605492) leucine-rich repeat neuro ( 713) 4794 525.7 2.4e-148
XP_016855539 (OMIM: 605492) PREDICTED: leucine-ric ( 713) 4794 525.7 2.4e-148
NP_004961 (OMIM: 601489,615961) insulin-like growt ( 605)  450 63.0   4e-09
NP_001139478 (OMIM: 601489,615961) insulin-like gr ( 643)  450 63.0 4.1e-09
NP_001264155 (OMIM: 606667) leucine-rich repeat-co ( 883)  441 62.3 9.7e-09
NP_003658 (OMIM: 606667) leucine-rich repeat-conta ( 907)  419 59.9   5e-08
NP_612449 (OMIM: 608843) vasorin precursor [Homo s ( 673)  412 59.0   7e-08
NP_060960 (OMIM: 606666,615311) leucine-rich repea ( 951)  407 58.7 1.2e-07
NP_001333361 (OMIM: 606666,615311) leucine-rich re ( 927)  398 57.7 2.4e-07
NP_848665 (OMIM: 610462) reticulon-4 receptor-like ( 420)  387 56.1 3.4e-07
XP_016857485 (OMIM: 606653) PREDICTED: leucine-ric ( 876)  391 56.9 3.9e-07
XP_011508141 (OMIM: 606653) PREDICTED: leucine-ric ( 900)  387 56.5 5.3e-07
NP_067649 (OMIM: 606653) leucine-rich repeat-conta ( 915)  387 56.5 5.3e-07
XP_005245461 (OMIM: 606653) PREDICTED: leucine-ric ( 924)  387 56.5 5.4e-07
NP_004479 (OMIM: 173511) platelet glycoprotein V p ( 560)  378 55.3 7.8e-07
XP_011531880 (OMIM: 608868) PREDICTED: leucine-ric (1045)  371 54.9 1.9e-06
NP_075380 (OMIM: 181500,605566) reticulon-4 recept ( 473)  364 53.7   2e-06
NP_001017403 (OMIM: 606653) leucine-rich repeat-co ( 967)  365 54.2 2.8e-06
XP_011508140 (OMIM: 606653) PREDICTED: leucine-ric ( 900)  361 53.8 3.6e-06
NP_001288124 (OMIM: 609791) leucine-rich repeat an ( 614)  354 52.8 4.8e-06
XP_011520420 (OMIM: 609791) PREDICTED: leucine-ric ( 614)  354 52.8 4.8e-06
NP_001288118 (OMIM: 609791) leucine-rich repeat an ( 614)  354 52.8 4.8e-06
NP_001288126 (OMIM: 609791) leucine-rich repeat an ( 614)  354 52.8 4.8e-06
NP_001288127 (OMIM: 609791) leucine-rich repeat an ( 614)  354 52.8 4.8e-06
NP_001288128 (OMIM: 609791) leucine-rich repeat an ( 614)  354 52.8 4.8e-06
NP_001288121 (OMIM: 609791) leucine-rich repeat an ( 614)  354 52.8 4.8e-06
NP_001288123 (OMIM: 609791) leucine-rich repeat an ( 614)  354 52.8 4.8e-06
NP_001288115 (OMIM: 609791) leucine-rich repeat an ( 614)  354 52.8 4.8e-06
XP_016878171 (OMIM: 609791) PREDICTED: leucine-ric ( 614)  354 52.8 4.8e-06
NP_001288116 (OMIM: 609791) leucine-rich repeat an ( 614)  354 52.8 4.8e-06
NP_001288129 (OMIM: 609791) leucine-rich repeat an ( 614)  354 52.8 4.8e-06
NP_001288120 (OMIM: 609791) leucine-rich repeat an ( 614)  354 52.8 4.8e-06
NP_116197 (OMIM: 609791) leucine-rich repeat and i ( 620)  354 52.8 4.9e-06
XP_016874279 (OMIM: 608870) PREDICTED: leucine-ric ( 623)  354 52.8 4.9e-06
XP_011536195 (OMIM: 608870) PREDICTED: leucine-ric (1041)  354 53.1 6.6e-06
NP_001129523 (OMIM: 608870) leucine-rich repeats a (1059)  354 53.1 6.6e-06
NP_700356 (OMIM: 608870) leucine-rich repeats and  (1119)  354 53.1 6.9e-06
XP_016859476 (OMIM: 610867) PREDICTED: leucine-ric ( 522)  347 51.9 7.4e-06
XP_016859475 (OMIM: 610867) PREDICTED: leucine-ric ( 522)  347 51.9 7.4e-06
NP_849161 (OMIM: 610867) leucine-rich repeat trans ( 522)  347 51.9 7.4e-06
NP_001258 (OMIM: 602178) chondroadherin precursor  ( 359)  344 51.4 7.4e-06
NP_001004432 (OMIM: 609794) leucine-rich repeat an ( 593)  347 52.0 7.9e-06
XP_011522516 (OMIM: 602178) PREDICTED: chondroadhe ( 440)  344 51.5 8.3e-06
NP_001245139 (OMIM: 608015) tsukushin isoform b pr ( 353)  339 50.9 1.1e-05
NP_001305408 (OMIM: 608015) tsukushin isoform b pr ( 353)  339 50.9 1.1e-05
NP_001305407 (OMIM: 608015) tsukushin isoform b pr ( 353)  339 50.9 1.1e-05
NP_056331 (OMIM: 608015) tsukushin isoform b precu ( 353)  339 50.9 1.1e-05


>>XP_011507368 (OMIM: 605492) PREDICTED: leucine-rich re  (713 aa)
 initn: 4794 init1: 4794 opt: 4794  Z-score: 2784.4  bits: 525.7 E(85289): 2.4e-148
Smith-Waterman score: 4794; 99.9% identity (100.0% similar) in 713 aa overlap (1-713:1-713)

               10        20        30        40        50        60
pF1KB3 MRLLVAPLLLAWVAGATATVPVVPWHVPCPPQCACQIRPWYTPRSSYREATTVDCNDLFL
       ::::::::::::::::::.:::::::::::::::::::::::::::::::::::::::::
XP_011 MRLLVAPLLLAWVAGATAAVPVVPWHVPCPPQCACQIRPWYTPRSSYREATTVDCNDLFL
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB3 TAVPPALPAGTQTLLLQSNSIVRVDQSELGYLANLTELDLSQNSFSDARDCDFHALPQLL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TAVPPALPAGTQTLLLQSNSIVRVDQSELGYLANLTELDLSQNSFSDARDCDFHALPQLL
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB3 SLHLEENQLTRLEDHSFAGLASLQELYLNHNQLYRIAPRAFSGLSNLLRLHLNSNLLRAI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SLHLEENQLTRLEDHSFAGLASLQELYLNHNQLYRIAPRAFSGLSNLLRLHLNSNLLRAI
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB3 DSRWFEMLPNLEILMIGGNKVDAILDMNFRPLANLRSLVLAGMNLREISDYALEGLQSLE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DSRWFEMLPNLEILMIGGNKVDAILDMNFRPLANLRSLVLAGMNLREISDYALEGLQSLE
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB3 SLSFYDNQLARVPRRALEQVPGLKFLDLNKNPLQRVGPGDFANMLHLKELGLNNMEELVS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SLSFYDNQLARVPRRALEQVPGLKFLDLNKNPLQRVGPGDFANMLHLKELGLNNMEELVS
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KB3 IDKFALVNLPELTKLDITNNPRLSFIHPRAFHHLPQMETLMLNNNALSALHQQTVESLPN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 IDKFALVNLPELTKLDITNNPRLSFIHPRAFHHLPQMETLMLNNNALSALHQQTVESLPN
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KB3 LQEVGLHGNPIRCDCVIRWANATGTRVRFIEPQSTLCAEPPDLQRLPVREVPFREMTDHC
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LQEVGLHGNPIRCDCVIRWANATGTRVRFIEPQSTLCAEPPDLQRLPVREVPFREMTDHC
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KB3 LPLISPRSFPPSLQVASGESMVLHCRALAEPEPEIYWVTPAGLRLTPAHAGRRYRVYPEG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LPLISPRSFPPSLQVASGESMVLHCRALAEPEPEIYWVTPAGLRLTPAHAGRRYRVYPEG
              430       440       450       460       470       480

              490       500       510       520       530       540
pF1KB3 TLELRRVTAEEAGLYTCVAQNLVGADTKTVSVVVGRALLQPGRDEGQGLELRVQETHPYH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TLELRRVTAEEAGLYTCVAQNLVGADTKTVSVVVGRALLQPGRDEGQGLELRVQETHPYH
              490       500       510       520       530       540

              550       560       570       580       590       600
pF1KB3 ILLSWVTPPNTVSTNLTWSSASSLRGQGATALARLPRGTHSYNITRLLQATEYWACLQVA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ILLSWVTPPNTVSTNLTWSSASSLRGQGATALARLPRGTHSYNITRLLQATEYWACLQVA
              550       560       570       580       590       600

              610       620       630       640       650       660
pF1KB3 FADAHTQLACVWARTKEATSCHRALGDRPGLIAILALAVLLLAAGLAAHLGTGQPRKGVG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FADAHTQLACVWARTKEATSCHRALGDRPGLIAILALAVLLLAAGLAAHLGTGQPRKGVG
              610       620       630       640       650       660

              670       680       690       700       710   
pF1KB3 GRRPLPPAWAFWGWSAPSVRVVSAPLVLPWNPGRKLPRSSEGETLLPPLSQNS
       :::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GRRPLPPAWAFWGWSAPSVRVVSAPLVLPWNPGRKLPRSSEGETLLPPLSQNS
              670       680       690       700       710   

>>NP_006329 (OMIM: 605492) leucine-rich repeat neuronal   (713 aa)
 initn: 4794 init1: 4794 opt: 4794  Z-score: 2784.4  bits: 525.7 E(85289): 2.4e-148
Smith-Waterman score: 4794; 99.9% identity (100.0% similar) in 713 aa overlap (1-713:1-713)

               10        20        30        40        50        60
pF1KB3 MRLLVAPLLLAWVAGATATVPVVPWHVPCPPQCACQIRPWYTPRSSYREATTVDCNDLFL
       ::::::::::::::::::.:::::::::::::::::::::::::::::::::::::::::
NP_006 MRLLVAPLLLAWVAGATAAVPVVPWHVPCPPQCACQIRPWYTPRSSYREATTVDCNDLFL
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB3 TAVPPALPAGTQTLLLQSNSIVRVDQSELGYLANLTELDLSQNSFSDARDCDFHALPQLL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 TAVPPALPAGTQTLLLQSNSIVRVDQSELGYLANLTELDLSQNSFSDARDCDFHALPQLL
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB3 SLHLEENQLTRLEDHSFAGLASLQELYLNHNQLYRIAPRAFSGLSNLLRLHLNSNLLRAI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 SLHLEENQLTRLEDHSFAGLASLQELYLNHNQLYRIAPRAFSGLSNLLRLHLNSNLLRAI
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB3 DSRWFEMLPNLEILMIGGNKVDAILDMNFRPLANLRSLVLAGMNLREISDYALEGLQSLE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 DSRWFEMLPNLEILMIGGNKVDAILDMNFRPLANLRSLVLAGMNLREISDYALEGLQSLE
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB3 SLSFYDNQLARVPRRALEQVPGLKFLDLNKNPLQRVGPGDFANMLHLKELGLNNMEELVS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 SLSFYDNQLARVPRRALEQVPGLKFLDLNKNPLQRVGPGDFANMLHLKELGLNNMEELVS
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KB3 IDKFALVNLPELTKLDITNNPRLSFIHPRAFHHLPQMETLMLNNNALSALHQQTVESLPN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 IDKFALVNLPELTKLDITNNPRLSFIHPRAFHHLPQMETLMLNNNALSALHQQTVESLPN
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KB3 LQEVGLHGNPIRCDCVIRWANATGTRVRFIEPQSTLCAEPPDLQRLPVREVPFREMTDHC
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 LQEVGLHGNPIRCDCVIRWANATGTRVRFIEPQSTLCAEPPDLQRLPVREVPFREMTDHC
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KB3 LPLISPRSFPPSLQVASGESMVLHCRALAEPEPEIYWVTPAGLRLTPAHAGRRYRVYPEG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 LPLISPRSFPPSLQVASGESMVLHCRALAEPEPEIYWVTPAGLRLTPAHAGRRYRVYPEG
              430       440       450       460       470       480

              490       500       510       520       530       540
pF1KB3 TLELRRVTAEEAGLYTCVAQNLVGADTKTVSVVVGRALLQPGRDEGQGLELRVQETHPYH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 TLELRRVTAEEAGLYTCVAQNLVGADTKTVSVVVGRALLQPGRDEGQGLELRVQETHPYH
              490       500       510       520       530       540

              550       560       570       580       590       600
pF1KB3 ILLSWVTPPNTVSTNLTWSSASSLRGQGATALARLPRGTHSYNITRLLQATEYWACLQVA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 ILLSWVTPPNTVSTNLTWSSASSLRGQGATALARLPRGTHSYNITRLLQATEYWACLQVA
              550       560       570       580       590       600

              610       620       630       640       650       660
pF1KB3 FADAHTQLACVWARTKEATSCHRALGDRPGLIAILALAVLLLAAGLAAHLGTGQPRKGVG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 FADAHTQLACVWARTKEATSCHRALGDRPGLIAILALAVLLLAAGLAAHLGTGQPRKGVG
              610       620       630       640       650       660

              670       680       690       700       710   
pF1KB3 GRRPLPPAWAFWGWSAPSVRVVSAPLVLPWNPGRKLPRSSEGETLLPPLSQNS
       :::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 GRRPLPPAWAFWGWSAPSVRVVSAPLVLPWNPGRKLPRSSEGETLLPPLSQNS
              670       680       690       700       710   

>>XP_005244884 (OMIM: 605492) PREDICTED: leucine-rich re  (713 aa)
 initn: 4794 init1: 4794 opt: 4794  Z-score: 2784.4  bits: 525.7 E(85289): 2.4e-148
Smith-Waterman score: 4794; 99.9% identity (100.0% similar) in 713 aa overlap (1-713:1-713)

               10        20        30        40        50        60
pF1KB3 MRLLVAPLLLAWVAGATATVPVVPWHVPCPPQCACQIRPWYTPRSSYREATTVDCNDLFL
       ::::::::::::::::::.:::::::::::::::::::::::::::::::::::::::::
XP_005 MRLLVAPLLLAWVAGATAAVPVVPWHVPCPPQCACQIRPWYTPRSSYREATTVDCNDLFL
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB3 TAVPPALPAGTQTLLLQSNSIVRVDQSELGYLANLTELDLSQNSFSDARDCDFHALPQLL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 TAVPPALPAGTQTLLLQSNSIVRVDQSELGYLANLTELDLSQNSFSDARDCDFHALPQLL
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB3 SLHLEENQLTRLEDHSFAGLASLQELYLNHNQLYRIAPRAFSGLSNLLRLHLNSNLLRAI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SLHLEENQLTRLEDHSFAGLASLQELYLNHNQLYRIAPRAFSGLSNLLRLHLNSNLLRAI
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB3 DSRWFEMLPNLEILMIGGNKVDAILDMNFRPLANLRSLVLAGMNLREISDYALEGLQSLE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 DSRWFEMLPNLEILMIGGNKVDAILDMNFRPLANLRSLVLAGMNLREISDYALEGLQSLE
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB3 SLSFYDNQLARVPRRALEQVPGLKFLDLNKNPLQRVGPGDFANMLHLKELGLNNMEELVS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SLSFYDNQLARVPRRALEQVPGLKFLDLNKNPLQRVGPGDFANMLHLKELGLNNMEELVS
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KB3 IDKFALVNLPELTKLDITNNPRLSFIHPRAFHHLPQMETLMLNNNALSALHQQTVESLPN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 IDKFALVNLPELTKLDITNNPRLSFIHPRAFHHLPQMETLMLNNNALSALHQQTVESLPN
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KB3 LQEVGLHGNPIRCDCVIRWANATGTRVRFIEPQSTLCAEPPDLQRLPVREVPFREMTDHC
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LQEVGLHGNPIRCDCVIRWANATGTRVRFIEPQSTLCAEPPDLQRLPVREVPFREMTDHC
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KB3 LPLISPRSFPPSLQVASGESMVLHCRALAEPEPEIYWVTPAGLRLTPAHAGRRYRVYPEG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LPLISPRSFPPSLQVASGESMVLHCRALAEPEPEIYWVTPAGLRLTPAHAGRRYRVYPEG
              430       440       450       460       470       480

              490       500       510       520       530       540
pF1KB3 TLELRRVTAEEAGLYTCVAQNLVGADTKTVSVVVGRALLQPGRDEGQGLELRVQETHPYH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 TLELRRVTAEEAGLYTCVAQNLVGADTKTVSVVVGRALLQPGRDEGQGLELRVQETHPYH
              490       500       510       520       530       540

              550       560       570       580       590       600
pF1KB3 ILLSWVTPPNTVSTNLTWSSASSLRGQGATALARLPRGTHSYNITRLLQATEYWACLQVA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 ILLSWVTPPNTVSTNLTWSSASSLRGQGATALARLPRGTHSYNITRLLQATEYWACLQVA
              550       560       570       580       590       600

              610       620       630       640       650       660
pF1KB3 FADAHTQLACVWARTKEATSCHRALGDRPGLIAILALAVLLLAAGLAAHLGTGQPRKGVG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 FADAHTQLACVWARTKEATSCHRALGDRPGLIAILALAVLLLAAGLAAHLGTGQPRKGVG
              610       620       630       640       650       660

              670       680       690       700       710   
pF1KB3 GRRPLPPAWAFWGWSAPSVRVVSAPLVLPWNPGRKLPRSSEGETLLPPLSQNS
       :::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 GRRPLPPAWAFWGWSAPSVRVVSAPLVLPWNPGRKLPRSSEGETLLPPLSQNS
              670       680       690       700       710   

>>NP_963924 (OMIM: 605492) leucine-rich repeat neuronal   (713 aa)
 initn: 4794 init1: 4794 opt: 4794  Z-score: 2784.4  bits: 525.7 E(85289): 2.4e-148
Smith-Waterman score: 4794; 99.9% identity (100.0% similar) in 713 aa overlap (1-713:1-713)

               10        20        30        40        50        60
pF1KB3 MRLLVAPLLLAWVAGATATVPVVPWHVPCPPQCACQIRPWYTPRSSYREATTVDCNDLFL
       ::::::::::::::::::.:::::::::::::::::::::::::::::::::::::::::
NP_963 MRLLVAPLLLAWVAGATAAVPVVPWHVPCPPQCACQIRPWYTPRSSYREATTVDCNDLFL
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB3 TAVPPALPAGTQTLLLQSNSIVRVDQSELGYLANLTELDLSQNSFSDARDCDFHALPQLL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_963 TAVPPALPAGTQTLLLQSNSIVRVDQSELGYLANLTELDLSQNSFSDARDCDFHALPQLL
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB3 SLHLEENQLTRLEDHSFAGLASLQELYLNHNQLYRIAPRAFSGLSNLLRLHLNSNLLRAI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_963 SLHLEENQLTRLEDHSFAGLASLQELYLNHNQLYRIAPRAFSGLSNLLRLHLNSNLLRAI
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB3 DSRWFEMLPNLEILMIGGNKVDAILDMNFRPLANLRSLVLAGMNLREISDYALEGLQSLE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_963 DSRWFEMLPNLEILMIGGNKVDAILDMNFRPLANLRSLVLAGMNLREISDYALEGLQSLE
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB3 SLSFYDNQLARVPRRALEQVPGLKFLDLNKNPLQRVGPGDFANMLHLKELGLNNMEELVS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_963 SLSFYDNQLARVPRRALEQVPGLKFLDLNKNPLQRVGPGDFANMLHLKELGLNNMEELVS
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KB3 IDKFALVNLPELTKLDITNNPRLSFIHPRAFHHLPQMETLMLNNNALSALHQQTVESLPN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_963 IDKFALVNLPELTKLDITNNPRLSFIHPRAFHHLPQMETLMLNNNALSALHQQTVESLPN
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KB3 LQEVGLHGNPIRCDCVIRWANATGTRVRFIEPQSTLCAEPPDLQRLPVREVPFREMTDHC
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_963 LQEVGLHGNPIRCDCVIRWANATGTRVRFIEPQSTLCAEPPDLQRLPVREVPFREMTDHC
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KB3 LPLISPRSFPPSLQVASGESMVLHCRALAEPEPEIYWVTPAGLRLTPAHAGRRYRVYPEG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_963 LPLISPRSFPPSLQVASGESMVLHCRALAEPEPEIYWVTPAGLRLTPAHAGRRYRVYPEG
              430       440       450       460       470       480

              490       500       510       520       530       540
pF1KB3 TLELRRVTAEEAGLYTCVAQNLVGADTKTVSVVVGRALLQPGRDEGQGLELRVQETHPYH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_963 TLELRRVTAEEAGLYTCVAQNLVGADTKTVSVVVGRALLQPGRDEGQGLELRVQETHPYH
              490       500       510       520       530       540

              550       560       570       580       590       600
pF1KB3 ILLSWVTPPNTVSTNLTWSSASSLRGQGATALARLPRGTHSYNITRLLQATEYWACLQVA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_963 ILLSWVTPPNTVSTNLTWSSASSLRGQGATALARLPRGTHSYNITRLLQATEYWACLQVA
              550       560       570       580       590       600

              610       620       630       640       650       660
pF1KB3 FADAHTQLACVWARTKEATSCHRALGDRPGLIAILALAVLLLAAGLAAHLGTGQPRKGVG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_963 FADAHTQLACVWARTKEATSCHRALGDRPGLIAILALAVLLLAAGLAAHLGTGQPRKGVG
              610       620       630       640       650       660

              670       680       690       700       710   
pF1KB3 GRRPLPPAWAFWGWSAPSVRVVSAPLVLPWNPGRKLPRSSEGETLLPPLSQNS
       :::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_963 GRRPLPPAWAFWGWSAPSVRVVSAPLVLPWNPGRKLPRSSEGETLLPPLSQNS
              670       680       690       700       710   

>>XP_016855539 (OMIM: 605492) PREDICTED: leucine-rich re  (713 aa)
 initn: 4794 init1: 4794 opt: 4794  Z-score: 2784.4  bits: 525.7 E(85289): 2.4e-148
Smith-Waterman score: 4794; 99.9% identity (100.0% similar) in 713 aa overlap (1-713:1-713)

               10        20        30        40        50        60
pF1KB3 MRLLVAPLLLAWVAGATATVPVVPWHVPCPPQCACQIRPWYTPRSSYREATTVDCNDLFL
       ::::::::::::::::::.:::::::::::::::::::::::::::::::::::::::::
XP_016 MRLLVAPLLLAWVAGATAAVPVVPWHVPCPPQCACQIRPWYTPRSSYREATTVDCNDLFL
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB3 TAVPPALPAGTQTLLLQSNSIVRVDQSELGYLANLTELDLSQNSFSDARDCDFHALPQLL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TAVPPALPAGTQTLLLQSNSIVRVDQSELGYLANLTELDLSQNSFSDARDCDFHALPQLL
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB3 SLHLEENQLTRLEDHSFAGLASLQELYLNHNQLYRIAPRAFSGLSNLLRLHLNSNLLRAI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SLHLEENQLTRLEDHSFAGLASLQELYLNHNQLYRIAPRAFSGLSNLLRLHLNSNLLRAI
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB3 DSRWFEMLPNLEILMIGGNKVDAILDMNFRPLANLRSLVLAGMNLREISDYALEGLQSLE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DSRWFEMLPNLEILMIGGNKVDAILDMNFRPLANLRSLVLAGMNLREISDYALEGLQSLE
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB3 SLSFYDNQLARVPRRALEQVPGLKFLDLNKNPLQRVGPGDFANMLHLKELGLNNMEELVS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SLSFYDNQLARVPRRALEQVPGLKFLDLNKNPLQRVGPGDFANMLHLKELGLNNMEELVS
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KB3 IDKFALVNLPELTKLDITNNPRLSFIHPRAFHHLPQMETLMLNNNALSALHQQTVESLPN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IDKFALVNLPELTKLDITNNPRLSFIHPRAFHHLPQMETLMLNNNALSALHQQTVESLPN
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KB3 LQEVGLHGNPIRCDCVIRWANATGTRVRFIEPQSTLCAEPPDLQRLPVREVPFREMTDHC
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LQEVGLHGNPIRCDCVIRWANATGTRVRFIEPQSTLCAEPPDLQRLPVREVPFREMTDHC
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KB3 LPLISPRSFPPSLQVASGESMVLHCRALAEPEPEIYWVTPAGLRLTPAHAGRRYRVYPEG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LPLISPRSFPPSLQVASGESMVLHCRALAEPEPEIYWVTPAGLRLTPAHAGRRYRVYPEG
              430       440       450       460       470       480

              490       500       510       520       530       540
pF1KB3 TLELRRVTAEEAGLYTCVAQNLVGADTKTVSVVVGRALLQPGRDEGQGLELRVQETHPYH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TLELRRVTAEEAGLYTCVAQNLVGADTKTVSVVVGRALLQPGRDEGQGLELRVQETHPYH
              490       500       510       520       530       540

              550       560       570       580       590       600
pF1KB3 ILLSWVTPPNTVSTNLTWSSASSLRGQGATALARLPRGTHSYNITRLLQATEYWACLQVA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ILLSWVTPPNTVSTNLTWSSASSLRGQGATALARLPRGTHSYNITRLLQATEYWACLQVA
              550       560       570       580       590       600

              610       620       630       640       650       660
pF1KB3 FADAHTQLACVWARTKEATSCHRALGDRPGLIAILALAVLLLAAGLAAHLGTGQPRKGVG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FADAHTQLACVWARTKEATSCHRALGDRPGLIAILALAVLLLAAGLAAHLGTGQPRKGVG
              610       620       630       640       650       660

              670       680       690       700       710   
pF1KB3 GRRPLPPAWAFWGWSAPSVRVVSAPLVLPWNPGRKLPRSSEGETLLPPLSQNS
       :::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GRRPLPPAWAFWGWSAPSVRVVSAPLVLPWNPGRKLPRSSEGETLLPPLSQNS
              670       680       690       700       710   

>>NP_004961 (OMIM: 601489,615961) insulin-like growth fa  (605 aa)
 initn: 336 init1: 336 opt: 450  Z-score: 284.8  bits: 63.0 E(85289): 4e-09
Smith-Waterman score: 450; 30.0% identity (58.6% similar) in 377 aa overlap (3-372:8-375)

                    10               20        30        40        
pF1KB3      MRLLVAPLLLAWVA-------GATATVPVVPWHVPCPPQCACQIRPWYTPRSSYR
              : .: :::.:::       ::   .:       ::  :.:.    :   .   
NP_004 MALRKGGLALALLLLSWVALGPRSLEGADPGTPGEAEGPACPAACVCS----YDDDA---
               10        20        30        40            50      

       50        60        70        80        90       100        
pF1KB3 EATTVDCNDLFLTAVPPALPAGTQTLLLQSNSIVRVDQSELGYLANLTELDLSQNSFSDA
       .  .: :..  :: .: ..:.:::.: :..:..  :  . .  :..:  :.:. ..... 
NP_004 DELSVFCSSRNLTRLPDGVPGGTQALWLDGNNLSSVPPAAFQNLSSLGFLNLQGGQLGSL
            60        70        80        90       100       110   

      110       120       130       140       150       160        
pF1KB3 RDCDFHALPQLLSLHLEENQLTRLEDHSFAGLASLQELYLNHNQLYRIAPRAFSGLSNLL
       .   . .: .:  ::::.:::  :   .::   .:  : :..:.: :.    : ::..: 
NP_004 EPQALLGLENLCHLHLERNQLRSLALGTFAHTPALASLGLSNNRLSRLEDGLFEGLGSLW
           120       130       140       150       160       170   

      170       180       190       200       210       220        
pF1KB3 RLHLNSNLLRAIDSRWFEMLPNLEILMIGGNKVDAILDMNFRPLANLRSLVLAGMNLREI
        :.:. : : .. .  :. : .:. :...::..  .    :  ::.:: : :.   :: :
NP_004 DLNLGWNSLAVLPDAAFRGLGSLRELVLAGNRLAYLQPALFSGLAELRELDLSRNALRAI
           180       190       200       210       220       230   

      230       240       250       260       270       280        
pF1KB3 SDYALEGLQSLESLSFYDNQLARVPRRALEQVPGLKFLDLNKNPLQRVGPGDFANMLHLK
       .  ..  :  :..: .  : .: :   :.  . .:..:::..: .  .    : ..: :.
NP_004 KANVFVQLPRLQKLYLDRNLIAAVAPGAFLGLKALRWLDLSHNRVAGLLEDTFPGLLGLR
           240       250       260       270       280       290   

      290       300       310       320       330       340        
pF1KB3 ELGLNNMEELVSIDKFALVNLPELTKLDITNNPRLSFIHPRAFHHLPQMETLMLNNNALS
        : :.. . ..:.   .. .:  : .:.. .: :.  .  :.:. : :.:.: :..: :.
NP_004 VLRLSH-NAIASLRPRTFKDLHFLEELQLGHN-RIRQLAERSFEGLGQLEVLTLDHNQLQ
            300       310       320        330       340       350 

      350       360       370       380       390       400        
pF1KB3 ALHQQTVESLPNLQEVGLHGNPIRCDCVIRWANATGTRVRFIEPQSTLCAEPPDLQRLPV
        ..  .  .: :.  ..: :: .:                                    
NP_004 EVKAGAFLGLTNVAVMNLSGNCLRNLPEQVFRGLGKLHSLHLEGSCLGRIRPHTFTGLSG
             360       370       380       390       400       410 

>>NP_001139478 (OMIM: 601489,615961) insulin-like growth  (643 aa)
 initn: 336 init1: 336 opt: 450  Z-score: 284.5  bits: 63.0 E(85289): 4.1e-09
Smith-Waterman score: 450; 30.0% identity (58.6% similar) in 377 aa overlap (3-372:46-413)

                                           10               20     
pF1KB3                             MRLLVAPLLLAWVA-------GATATVPVVPW
                                     : .: :::.:::       ::   .:    
NP_001 ERRFRLCWYQAHSGRALLGPPPQASPPAGGLALALLLLSWVALGPRSLEGADPGTPGEAE
          20        30        40        50        60        70     

          30        40        50        60        70        80     
pF1KB3 HVPCPPQCACQIRPWYTPRSSYREATTVDCNDLFLTAVPPALPAGTQTLLLQSNSIVRVD
          ::  :.:.    :   .   .  .: :..  :: .: ..:.:::.: :..:..  : 
NP_001 GPACPAACVCS----YDDDA---DELSVFCSSRNLTRLPDGVPGGTQALWLDGNNLSSVP
          80            90          100       110       120        

          90       100       110       120       130       140     
pF1KB3 QSELGYLANLTELDLSQNSFSDARDCDFHALPQLLSLHLEENQLTRLEDHSFAGLASLQE
        . .  :..:  :.:. ..... .   . .: .:  ::::.:::  :   .::   .:  
NP_001 PAAFQNLSSLGFLNLQGGQLGSLEPQALLGLENLCHLHLERNQLRSLALGTFAHTPALAS
      130       140       150       160       170       180        

         150       160       170       180       190       200     
pF1KB3 LYLNHNQLYRIAPRAFSGLSNLLRLHLNSNLLRAIDSRWFEMLPNLEILMIGGNKVDAIL
       : :..:.: :.    : ::..:  :.:. : : .. .  :. : .:. :...::..  . 
NP_001 LGLSNNRLSRLEDGLFEGLGSLWDLNLGWNSLAVLPDAAFRGLGSLRELVLAGNRLAYLQ
      190       200       210       220       230       240        

         210       220       230       240       250       260     
pF1KB3 DMNFRPLANLRSLVLAGMNLREISDYALEGLQSLESLSFYDNQLARVPRRALEQVPGLKF
          :  ::.:: : :.   :: :.  ..  :  :..: .  : .: :   :.  . .:..
NP_001 PALFSGLAELRELDLSRNALRAIKANVFVQLPRLQKLYLDRNLIAAVAPGAFLGLKALRW
      250       260       270       280       290       300        

         270       280       290       300       310       320     
pF1KB3 LDLNKNPLQRVGPGDFANMLHLKELGLNNMEELVSIDKFALVNLPELTKLDITNNPRLSF
       :::..: .  .    : ..: :. : :.. . ..:.   .. .:  : .:.. .: :.  
NP_001 LDLSHNRVAGLLEDTFPGLLGLRVLRLSH-NAIASLRPRTFKDLHFLEELQLGHN-RIRQ
      310       320       330        340       350       360       

         330       340       350       360       370       380     
pF1KB3 IHPRAFHHLPQMETLMLNNNALSALHQQTVESLPNLQEVGLHGNPIRCDCVIRWANATGT
       .  :.:. : :.:.: :..: :. ..  .  .: :.  ..: :: .:             
NP_001 LAERSFEGLGQLEVLTLDHNQLQEVKAGAFLGLTNVAVMNLSGNCLRNLPEQVFRGLGKL
        370       380       390       400       410       420      

         390       400       410       420       430       440     
pF1KB3 RVRFIEPQSTLCAEPPDLQRLPVREVPFREMTDHCLPLISPRSFPPSLQVASGESMVLHC
                                                                   
NP_001 HSLHLEGSCLGRIRPHTFTGLSGLRRLFLKDNGLVGIEEQSLWGLAELLELDLTSNQLTH
        430       440       450       460       470       480      

>>NP_001264155 (OMIM: 606667) leucine-rich repeat-contai  (883 aa)
 initn: 420 init1: 311 opt: 441  Z-score: 277.9  bits: 62.3 E(85289): 9.7e-09
Smith-Waterman score: 452; 30.5% identity (58.4% similar) in 370 aa overlap (3-371:9-362)

                     10        20        30        40        50    
pF1KB3       MRLLVAPLLLAWVAGATATVPVVPWHVPCPPQCACQIRPWYTPRSSYREATTVD
               ::  :.::  ..:...    :  .  :: .: :.      : .  :    ::
NP_001 MDTSRLGVLLSLPVLLQLATGGSSPRSGVLLR-GCPTHCHCE------PDG--RMLLRVD
               10        20        30         40                50 

           60        70        80        90       100       110    
pF1KB3 CNDLFLTAVPPALPAGTQTLLLQSNSIVRVDQSELGYLANLTELDLSQNSFSDARDCDFH
       :.:: :. .:  : . :. : :. :.: ..  . :  :  : :: :. :...      : 
NP_001 CSDLGLSELPSNLSVFTSYLDLSMNNISQLLPNPLPSLRFLEELRLAGNALTYIPKGAFT
              60        70        80        90       100       110 

          120       130       140       150       160       170    
pF1KB3 ALPQLLSLHLEENQLTRLEDHSFAGLASLQELYLNHNQLYRIAPRAFSGLSNLLRLHLNS
       .: .:  : :..::: ..  ... .: ::: : :. :..  . :  :::: .: .: :..
NP_001 GLYSLKVLMLQNNQLRHVPTEALQNLRSLQSLRLDANHISYVPPSCFSGLHSLRHLWLDD
             120       130       140       150       160       170 

          180       190       200       210       220       230    
pF1KB3 NLLRAIDSRWFEMLPNLEILMIGGNKVDAILDMNFRPLANLRSLVLAGMNLREISDYALE
       : :  :  . :. :  :. . .. ::.  : :. :  :..:  : : .  .. ..   ..
NP_001 NALTEIPVQAFRSLSALQAMTLALNKIHHIPDYAFGNLSSLVVLHLHNNRIHSLGKKCFD
             180       190       200       210       220       230 

          240       250       260       270       280       290    
pF1KB3 GLQSLESLSFYDNQLARVPRRALEQVPGLKFLDLNKNPLQRVGPGDFANMLHLKELGLNN
       ::.:::.:..  :.: . :  :.. . .:: : .  ::.: :: . : .. .:. : ::.
NP_001 GLHSLETLDLNYNNLDEFPT-AIRTLSNLKELHFYDNPIQFVGRSAFQHLPELRTLTLNG
             240       250        260       270       280       290

          300        310       320       330       340       350   
pF1KB3 MEELVSI-DKFALVNLPELTKLDITNNPRLSFIHPRAFHHLPQMETLMLNNNALSALHQQ
         ... . :  . .::  ::     .. ..: .   . ..::....: :. : :  : . 
NP_001 ASQITEFPDLTGTANLESLT----LTGAQISSLPQTVCNQLPNLQVLDLSYNLLEDLPSF
              300       310           320       330       340      

           360       370       380       390       400       410   
pF1KB3 TVESLPNLQEVGLHGNPIRCDCVIRWANATGTRVRFIEPQSTLCAEPPDLQRLPVREVPF
       .: .  .::.. :. : :                                          
NP_001 SVCQ--KLQKIDLRHNEIYEIKVDTFQQLLSLRSLNLAWNKIAIIHPNAFSTLPSLIKLD
        350         360       370       380       390       400    

>>NP_003658 (OMIM: 606667) leucine-rich repeat-containin  (907 aa)
 initn: 778 init1: 297 opt: 419  Z-score: 265.1  bits: 59.9 E(85289): 5e-08
Smith-Waterman score: 444; 28.7% identity (56.4% similar) in 456 aa overlap (3-449:9-419)

                     10        20        30        40        50    
pF1KB3       MRLLVAPLLLAWVAGATATVPVVPWHVPCPPQCACQIRPWYTPRSSYREATTVD
               ::  :.::  ..:...    :  .  :: .: :.      : .  :    ::
NP_003 MDTSRLGVLLSLPVLLQLATGGSSPRSGVLLR-GCPTHCHCE------PDG--RMLLRVD
               10        20        30         40                50 

           60        70        80        90       100       110    
pF1KB3 CNDLFLTAVPPALPAGTQTLLLQSNSIVRVDQSELGYLANLTELDLSQNSFSDARDCDFH
       :.:: :. .:  : . :. : :. :.: ..  . :  :  : :: :. :...      : 
NP_003 CSDLGLSELPSNLSVFTSYLDLSMNNISQLLPNPLPSLRFLEELRLAGNALTYIPKGAFT
              60        70        80        90       100       110 

          120       130       140       150       160       170    
pF1KB3 ALPQLLSLHLEENQLTRLEDHSFAGLASLQELYLNHNQLYRIAPRAFSGLSNLLRLHLNS
       .: .:  : :..::: ..  ... .: ::: : :. :..  . :  :::: .: .: :..
NP_003 GLYSLKVLMLQNNQLRHVPTEALQNLRSLQSLRLDANHISYVPPSCFSGLHSLRHLWLDD
             120       130       140       150       160       170 

          180       190       200       210       220       230    
pF1KB3 NLLRAIDSRWFEMLPNLEILMIGGNKVDAILDMNFRPLANLRSLVLAGMNLREISDYALE
       : :  :        :           :.:     :: :. :....::  ....: :::. 
NP_003 NALTEI--------P-----------VQA-----FRSLSALQAMTLALNKIHHIPDYAFG
                                180            190       200       

          240       250       260       270       280       290    
pF1KB3 GLQSLESLSFYDNQLARVPRRALEQVPGLKFLDLNKNPLQRVGPGDFANMLHLKELGLNN
       .:.::  : ...:..  . .. .. . .:. :::: : :..  :  . .. .:::::...
NP_003 NLSSLVVLHLHNNRIHSLGKKCFDGLHSLETLDLNYNNLDEF-PTAIRTLSNLKELGFHS
       210       220       230       240        250       260      

          300       310       320       330       340       350    
pF1KB3 MEELVSIDKFALVNLPELTKLDITNNPRLSFIHPRAFHHLPQMETLMLNNNALSALHQQT
        ... :: . :.:. : :  . . .:: ..:.   ::.:::...:: ::. : .  .   
NP_003 -NNIRSIPEKAFVGNPSLITIHFYDNP-IQFVGRSAFQHLPELRTLTLNG-ASQITEFPD
         270       280       290        300       310        320   

          360       370             380       390         400      
pF1KB3 VESLPNLQEVGLHGNPIR------CDCVIRWANATGTRVRFIE--PQSTLCAEPPDLQRL
       . .  ::. . : :  :       :. .    ..      ..:  :. ..: .   ::..
NP_003 LTGTANLESLTLTGAQISSLPQTVCNQLPNL-QVLDLSYNLLEDLPSFSVCQK---LQKI
           330       340       350        360       370            

        410        420       430       440       450       460     
pF1KB3 PVREVPFREM-TDHCLPLISPRSFPPSLQVASGESMVLHCRALAEPEPEIYWVTPAGLRL
        .:.  . :. .:    :.: ::    :..: ..  ..:  :..                
NP_003 DLRHNEIYEIKVDTFQQLLSLRS----LNLAWNKIAIIHPNAFSTLPSLIKLDLSSNLLS
     380       390       400           410       420       430     

         470       480       490       500       510       520     
pF1KB3 TPAHAGRRYRVYPEGTLELRRVTAEEAGLYTCVAQNLVGADTKTVSVVVGRALLQPGRDE
                                                                   
NP_003 SFPITGLHGLTHLKLTGNHALQSLISSENFPELKVIEMPYAYQCCAFGVCENAYKISNQW
         440       450       460       470       480       490     

>>NP_612449 (OMIM: 608843) vasorin precursor [Homo sapie  (673 aa)
 initn: 371 init1: 232 opt: 412  Z-score: 262.4  bits: 59.0 E(85289): 7e-08
Smith-Waterman score: 434; 26.9% identity (51.7% similar) in 714 aa overlap (4-697:7-666)

                  10        20        30        40        50       
pF1KB3    MRLLVAPLLLAWVAGATATVPVVPWHVPCPPQCACQIRPWYTPRSSYREATTVDCND
             :. ::::  . :     : :     ::  : :. .:            :: :. 
NP_612 MCSRVPLLLPLLLLLALG-----PGVQ---GCPSGCQCS-QPQ-----------TVFCTA
               10             20           30                    40

        60        70        80        90       100       110       
pF1KB3 LFLTAVPPALPAGTQTLLLQSNSIVRVDQSELGYLANLTELDLSQNSFSDARDCDFHALP
          :.::  .:  :  : .  :.:. .: . .. : .:  ::::::....  .  :. : 
NP_612 RQGTTVPRDVPPDTVGLYVFENGITMLDAGSFAGLPGLQLLDLSQNQIASLPSGVFQPLA
               50        60        70        80        90       100

       120       130       140       150       160       170       
pF1KB3 QLLSLHLEENQLTRLEDHSFAGLASLQELYLNHNQLYRIAPRAFSGLSNLLRLHLNSNLL
       .: .: :  :.: .. ...: ::  :..:::..:.. .: : ::. :. ::.:.:..: :
NP_612 NLSNLDLTANRLHEITNETFRGLRRLERLYLGKNRIRHIQPGAFDTLDRLLELKLQDNEL
              110       120       130       140       150       160

       180       190       200       210       220       230       
pF1KB3 RAIDSRWFEMLPNLEILMIGGNKVDAILDMNFRPLANLRSLVLAGMNLREISDYALEGLQ
       ::.       :: : .: .. :.. : :. ..   ::...: :::..:.....  .  :.
NP_612 RALPPL---RLPRLLLLDLSHNSLLA-LEPGILDTANVEALRLAGLGLQQLDEGLFSRLR
                 170       180        190       200       210      

       240       250       260       270        280       290      
pF1KB3 SLESLSFYDNQLARVPRRALEQVPGLKFLDLNKNP-LQRVGPGDFANMLHLKELGLNNME
       .:..:.  :::: :::  ... . ::  : :  :  . .. : :.:..  :.:: ..:. 
NP_612 NLHDLDVSDNQLERVPP-VIRGLRGLTRLRLAGNTRIAQLRPEDLAGLAALQELDVSNLS
        220       230        240       250       260       270     

         300       310       320       330       340       350     
pF1KB3 -ELVSIDKFALVNLPELTKLDITNNPRLSFIHPRAFHHLPQMETLMLNNNALSALHQQTV
        . .  :  .:  .:.:  :  . :: .. . : ..   : ..    ....  :  ..: 
NP_612 LQALPGDLSGL--FPRLRLLAAARNP-FNCVCPLSWFG-PWVR----ESHVTLASPEETR
         280         290        300       310            320       

           360       370       380       390         400           
pF1KB3 ESLP--NLQEVGLHGNPIRCDCVIRWANATGTRVRFI--EPQSTLCAEPPDL--QRLPVR
         .:  :  .. :. .     :    ..::   .: .  :: .   .  :       :. 
NP_612 CHFPPKNAGRLLLELDYADFGCPATTTTATVPTTRPVVREPTALSSSLAPTWLSPTEPAT
       330       340       350       360       370       380       

     410         420       430       440       450           460   
pF1KB3 EVPFREMT--DHCLPLISPRSFPPSLQVASGESMVLHCRALAEPEPE----IYWVTPAGL
       :.:    :      :. .:.. :::  . .:   .   . ::   ::    .:  .  : 
NP_612 EAPSPPSTAPPTVGPVPQPQDCPPSTCLNGGTCHLGTRHHLACLCPEGFTGLYCESQMGQ
       390       400       410       420       430       440       

           470       480       490       500       510        520  
pF1KB3 RLTPAHAGRRYRVYPEGTLELRRVTAEEAGLYTCVAQNLVGADTKTVSV-VVGRALLQPG
          :. .    :  :  .: :    .  ..: . . . : :....  :. .. : :  : 
NP_612 GTRPSPTPVTPR--PPRSLTLGIEPVSPTSLRVGLQRYLQGSSVQLRSLRLTYRNLSGPD
       450         460       470       480       490       500     

            530       540       550       560        570       580 
pF1KB3 RDEGQGLELRVQETHPYHILLSWVTPPNTVSTNLTWSSASSL-RGQGATALARLPRGTHS
       .   . . ::.  .   . . . . :  : :. .   . . . .:. : . :. : ..::
NP_612 K---RLVTLRLPASLAEYTV-TQLRPNATYSVCVMPLGPGRVPEGEEACGEAHTPPAVHS
            510       520        530       540       550       560 

             590       600       610       620       630       640 
pF1KB3 YNITRLLQATEYWACLQVAFADAHTQLACVWARTKEATSCHRALGDRPGLIAILALAVLL
        : . . :: :    : .: : : . :: . :    :. : :  :         :.:.  
NP_612 -NHAPVTQAREGNLPLLIAPALAAVLLAALAAVG--AAYCVRR-GR--------AMAA--
              570       580       590         600                  

             650        660          670       680       690       
pF1KB3 LAAGLAAHLGTGQ-PRKGVGGRRPLPP---AWAFWGWSAPSVRVVSAPLVLPWNPGRKLP
        ::   ...: :  : .  : . :: :   :    : . ::     .::.   .:: . :
NP_612 -AAQDKGQVGPGAGPLELEGVKVPLEPGPKATEGGGEALPSGSECEVPLMGFPGPGLQSP
        610       620       630       640       650       660      

       700       710   
pF1KB3 RSSEGETLLPPLSQNS
                       
NP_612 LHAKPYI         
        670            




713 residues in 1 query   sequences
60827320 residues in 85289 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Thu Nov  3 20:50:26 2016 done: Thu Nov  3 20:50:28 2016
 Total Scan time: 10.310 Total Display time:  0.130

Function used was FASTA [36.3.4 Apr, 2011]
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