Result of FASTA (omim) for pF1KA0288
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KA0288, 1084 aa
  1>>>pF1KA0288 1084 - 1084 aa - 1084 aa
Library: /omim/omim.rfq.tfa
  60827320 residues in 85289 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 11.6445+/-0.000461; mu= -7.8346+/- 0.028
 mean_var=337.7576+/-71.901, 0's: 0 Z-trim(120.2): 146  B-trim: 1480 in 2/57
 Lambda= 0.069787
 statistics sampled from 35098 (35248) to 35098 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.728), E-opt: 0.2 (0.413), width:  16
 Scan time: 17.320

The best scores are:                                      opt bits E(85289)
NP_006028 (OMIM: 605314) histone deacetylase 4 [Ho (1084) 7222 742.0 4.4e-213
XP_011510525 (OMIM: 605314) PREDICTED: histone dea (1089) 7202 740.0 1.8e-212
XP_006712941 (OMIM: 605314) PREDICTED: histone dea (1089) 7202 740.0 1.8e-212
XP_011510523 (OMIM: 605314) PREDICTED: histone dea (1089) 7202 740.0 1.8e-212
XP_011510524 (OMIM: 605314) PREDICTED: histone dea (1089) 7202 740.0 1.8e-212
XP_011510527 (OMIM: 605314) PREDICTED: histone dea (1079) 7173 737.0 1.3e-211
XP_006712940 (OMIM: 605314) PREDICTED: histone dea (1108) 7173 737.1 1.4e-211
XP_011510526 (OMIM: 605314) PREDICTED: histone dea (1084) 7153 735.0 5.4e-211
XP_011510522 (OMIM: 605314) PREDICTED: histone dea (1090) 7153 735.0 5.4e-211
XP_011510519 (OMIM: 605314) PREDICTED: histone dea (1113) 7153 735.0 5.5e-211
XP_011510521 (OMIM: 605314) PREDICTED: histone dea (1103) 7123 732.0 4.4e-210
XP_011510520 (OMIM: 605314) PREDICTED: histone dea (1108) 7103 730.0 1.8e-209
XP_006712942 (OMIM: 605314) PREDICTED: histone dea (1062) 7015 721.1 8.1e-207
XP_006712943 (OMIM: 605314) PREDICTED: histone dea (1062) 7015 721.1 8.1e-207
XP_011510528 (OMIM: 605314) PREDICTED: histone dea (1065) 6988 718.4 5.3e-206
XP_011510529 (OMIM: 605314) PREDICTED: histone dea (1041) 6883 707.8  8e-203
XP_016860884 (OMIM: 605314) PREDICTED: histone dea ( 917) 6083 627.3 1.3e-178
XP_016860883 (OMIM: 605314) PREDICTED: histone dea (1069) 5381 556.6 2.7e-157
XP_011510532 (OMIM: 605314) PREDICTED: histone dea ( 673) 4469 464.7 8.1e-130
XP_011513931 (OMIM: 606543) PREDICTED: histone dea (1088) 3947 412.3  8e-114
XP_011513940 (OMIM: 606543) PREDICTED: histone dea (1069) 3906 408.1 1.4e-112
NP_848512 (OMIM: 606543) histone deacetylase 9 iso (1069) 3906 408.1 1.4e-112
XP_011513941 (OMIM: 606543) PREDICTED: histone dea (1069) 3906 408.1 1.4e-112
XP_016868315 (OMIM: 606543) PREDICTED: histone dea (1066) 3878 405.3 9.7e-112
NP_848510 (OMIM: 606543) histone deacetylase 9 iso (1066) 3878 405.3 9.7e-112
XP_011513946 (OMIM: 606543) PREDICTED: histone dea (1038) 3834 400.9  2e-110
XP_011513947 (OMIM: 606543) PREDICTED: histone dea (1038) 3834 400.9  2e-110
XP_011513948 (OMIM: 606543) PREDICTED: histone dea (1035) 3806 398.0 1.4e-109
NP_478056 (OMIM: 606543) histone deacetylase 9 iso (1011) 3744 391.8 1.1e-107
XP_011513939 (OMIM: 606543) PREDICTED: histone dea (1071) 3496 366.8 3.7e-100
XP_011513938 (OMIM: 606543) PREDICTED: histone dea (1071) 3496 366.8 3.7e-100
XP_016868316 (OMIM: 606543) PREDICTED: histone dea (1043) 3480 365.2 1.1e-99
XP_011513944 (OMIM: 606543) PREDICTED: histone dea (1043) 3480 365.2 1.1e-99
XP_011513943 (OMIM: 606543) PREDICTED: histone dea (1043) 3480 365.2 1.1e-99
XP_011513937 (OMIM: 606543) PREDICTED: histone dea (1074) 3480 365.2 1.1e-99
XP_011513950 (OMIM: 606543) PREDICTED: histone dea (1074) 3480 365.2 1.1e-99
XP_011513951 (OMIM: 606543) PREDICTED: histone dea (1074) 3480 365.2 1.1e-99
XP_011513933 (OMIM: 606543) PREDICTED: histone dea (1096) 3480 365.2 1.1e-99
XP_016879481 (OMIM: 605315) PREDICTED: histone dea (1156) 2978 314.7   2e-84
XP_016879484 (OMIM: 605315) PREDICTED: histone dea (1113) 2961 313.0 6.2e-84
XP_011522451 (OMIM: 605315) PREDICTED: histone dea (1114) 2961 313.0 6.2e-84
XP_016879482 (OMIM: 605315) PREDICTED: histone dea (1152) 2961 313.0 6.4e-84
XP_005256962 (OMIM: 605315) PREDICTED: histone dea (1122) 2952 312.1 1.2e-83
XP_016879480 (OMIM: 605315) PREDICTED: histone dea (1160) 2952 312.1 1.2e-83
XP_016879485 (OMIM: 605315) PREDICTED: histone dea (1081) 2946 311.5 1.7e-83
XP_011522452 (OMIM: 605315) PREDICTED: histone dea (1113) 2946 311.5 1.8e-83
NP_005465 (OMIM: 605315) histone deacetylase 5 iso (1122) 2946 311.5 1.8e-83
XP_005256963 (OMIM: 605315) PREDICTED: histone dea (1122) 2946 311.5 1.8e-83
NP_001015053 (OMIM: 605315) histone deacetylase 5  (1123) 2946 311.5 1.8e-83
XP_016879479 (OMIM: 605315) PREDICTED: histone dea (1160) 2946 311.5 1.8e-83


>>NP_006028 (OMIM: 605314) histone deacetylase 4 [Homo s  (1084 aa)
 initn: 7222 init1: 7222 opt: 7222  Z-score: 3946.5  bits: 742.0 E(85289): 4.4e-213
Smith-Waterman score: 7222; 100.0% identity (100.0% similar) in 1084 aa overlap (1-1084:1-1084)

               10        20        30        40        50        60
pF1KA0 MSSQSHPDGLSGRDQPVELLNPARVNHMPSTVDVATALPLQVAPSAVPMDLRLDHQFSLP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 MSSQSHPDGLSGRDQPVELLNPARVNHMPSTVDVATALPLQVAPSAVPMDLRLDHQFSLP
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KA0 VAEPALREQQLQQELLALKQKQQIQRQILIAEFQRQHEQLSRQHEAQLHEHIKQQQEMLA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 VAEPALREQQLQQELLALKQKQQIQRQILIAEFQRQHEQLSRQHEAQLHEHIKQQQEMLA
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KA0 MKHQQELLEHQRKLERHRQEQELEKQHREQKLQQLKNKEKGKESAVASTEVKMKLQEFVL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 MKHQQELLEHQRKLERHRQEQELEKQHREQKLQQLKNKEKGKESAVASTEVKMKLQEFVL
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KA0 NKKKALAHRNLNHCISSDPRYWYGKTQHSSLDQSSPPQSGVSTSYNHPVLGMYDAKDDFP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 NKKKALAHRNLNHCISSDPRYWYGKTQHSSLDQSSPPQSGVSTSYNHPVLGMYDAKDDFP
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KA0 LRKTASEPNLKLRSRLKQKVAERRSSPLLRRKDGPVVTALKKRPLDVTDSACSSAPGSGP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 LRKTASEPNLKLRSRLKQKVAERRSSPLLRRKDGPVVTALKKRPLDVTDSACSSAPGSGP
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KA0 SSPNNSSGSVSAENGIAPAVPSIPAETSLAHRLVAREGSAAPLPLYTSPSLPNITLGLPA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 SSPNNSSGSVSAENGIAPAVPSIPAETSLAHRLVAREGSAAPLPLYTSPSLPNITLGLPA
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KA0 TGPSAGTAGQQDAERLTLPALQQRLSLFPGTHLTPYLSTSPLERDGGAAHSPLLQHMVLL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 TGPSAGTAGQQDAERLTLPALQQRLSLFPGTHLTPYLSTSPLERDGGAAHSPLLQHMVLL
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KA0 EQPPAQAPLVTGLGALPLHAQSLVGADRVSPSIHKLRQHRPLGRTQSAPLPQNAQALQHL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 EQPPAQAPLVTGLGALPLHAQSLVGADRVSPSIHKLRQHRPLGRTQSAPLPQNAQALQHL
              430       440       450       460       470       480

              490       500       510       520       530       540
pF1KA0 VIQQQHQQFLEKHKQQFQQQQLQMNKIIPKPSEPARQPESHPEETEEELREHQALLDEPY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 VIQQQHQQFLEKHKQQFQQQQLQMNKIIPKPSEPARQPESHPEETEEELREHQALLDEPY
              490       500       510       520       530       540

              550       560       570       580       590       600
pF1KA0 LDRLPGQKEAHAQAGVQVKQEPIESDEEEAEPPREVEPGQRQPSEQELLFRQQALLLEQQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 LDRLPGQKEAHAQAGVQVKQEPIESDEEEAEPPREVEPGQRQPSEQELLFRQQALLLEQQ
              550       560       570       580       590       600

              610       620       630       640       650       660
pF1KA0 RIHQLRNYQASMEAAGIPVSFGGHRPLSRAQSSPASATFPVSVQEPPTKPRFTTGLVYDT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 RIHQLRNYQASMEAAGIPVSFGGHRPLSRAQSSPASATFPVSVQEPPTKPRFTTGLVYDT
              610       620       630       640       650       660

              670       680       690       700       710       720
pF1KA0 LMLKHQCTCGSSSSHPEHAGRIQSIWSRLQETGLRGKCECIRGRKATLEELQTVHSEAHT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 LMLKHQCTCGSSSSHPEHAGRIQSIWSRLQETGLRGKCECIRGRKATLEELQTVHSEAHT
              670       680       690       700       710       720

              730       740       750       760       770       780
pF1KA0 LLYGTNPLNRQKLDSKKLLGSLASVFVRLPCGGVGVDSDTIWNEVHSAGAARLAVGCVVE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 LLYGTNPLNRQKLDSKKLLGSLASVFVRLPCGGVGVDSDTIWNEVHSAGAARLAVGCVVE
              730       740       750       760       770       780

              790       800       810       820       830       840
pF1KA0 LVFKVATGELKNGFAVVRPPGHHAEESTPMGFCYFNSVAVAAKLLQQRLSVSKILIVDWD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 LVFKVATGELKNGFAVVRPPGHHAEESTPMGFCYFNSVAVAAKLLQQRLSVSKILIVDWD
              790       800       810       820       830       840

              850       860       870       880       890       900
pF1KA0 VHHGNGTQQAFYSDPSVLYMSLHRYDDGNFFPGSGAPDEVGTGPGVGFNVNMAFTGGLDP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 VHHGNGTQQAFYSDPSVLYMSLHRYDDGNFFPGSGAPDEVGTGPGVGFNVNMAFTGGLDP
              850       860       870       880       890       900

              910       920       930       940       950       960
pF1KA0 PMGDAEYLAAFRTVVMPIASEFAPDVVLVSSGFDAVEGHPTPLGGYNLSARCFGYLTKQL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 PMGDAEYLAAFRTVVMPIASEFAPDVVLVSSGFDAVEGHPTPLGGYNLSARCFGYLTKQL
              910       920       930       940       950       960

              970       980       990      1000      1010      1020
pF1KA0 MGLAGGRIVLALEGGHDLTAICDASEACVSALLGNELDPLPEKVLQQRPNANAVRSMEKV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 MGLAGGRIVLALEGGHDLTAICDASEACVSALLGNELDPLPEKVLQQRPNANAVRSMEKV
              970       980       990      1000      1010      1020

             1030      1040      1050      1060      1070      1080
pF1KA0 MEIHSKYWRCLQRTTSTAGRSLIEAQTCENEEAETVTAMASLSVGVKPAEKRPDEEPMEE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 MEIHSKYWRCLQRTTSTAGRSLIEAQTCENEEAETVTAMASLSVGVKPAEKRPDEEPMEE
             1030      1040      1050      1060      1070      1080

           
pF1KA0 EPPL
       ::::
NP_006 EPPL
           

>>XP_011510525 (OMIM: 605314) PREDICTED: histone deacety  (1089 aa)
 initn: 4395 init1: 4395 opt: 7202  Z-score: 3935.6  bits: 740.0 E(85289): 1.8e-212
Smith-Waterman score: 7202; 99.5% identity (99.5% similar) in 1089 aa overlap (1-1084:1-1089)

               10        20        30        40        50        60
pF1KA0 MSSQSHPDGLSGRDQPVELLNPARVNHMPSTVDVATALPLQVAPSAVPMDLRLDHQFSLP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MSSQSHPDGLSGRDQPVELLNPARVNHMPSTVDVATALPLQVAPSAVPMDLRLDHQFSLP
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KA0 VAEPALREQQLQQELLALKQKQQIQRQILIAEFQRQHEQLSRQHEAQLHEHIKQQQEMLA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VAEPALREQQLQQELLALKQKQQIQRQILIAEFQRQHEQLSRQHEAQLHEHIKQQQEMLA
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KA0 MKHQQELLEHQRKLERHRQEQELEKQHREQKLQQLKNKEKGKESAVASTEVKMKLQEFVL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MKHQQELLEHQRKLERHRQEQELEKQHREQKLQQLKNKEKGKESAVASTEVKMKLQEFVL
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KA0 NKKKALAHRNLNHCISSDPRYWYGKTQHSSLDQSSPPQSGVSTSYNHPVLGMYDAKDDFP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NKKKALAHRNLNHCISSDPRYWYGKTQHSSLDQSSPPQSGVSTSYNHPVLGMYDAKDDFP
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KA0 LRKTASEPNLKLRSRLKQKVAERRSSPLLRRKDGPVVTALKKRPLDVTDSACSSAPGSGP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LRKTASEPNLKLRSRLKQKVAERRSSPLLRRKDGPVVTALKKRPLDVTDSACSSAPGSGP
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KA0 SSPNNSSGSVSAENGIAPAVPSIPAETSLAHRLVAREGSAAPLPLYTSPSLPNITLGLPA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SSPNNSSGSVSAENGIAPAVPSIPAETSLAHRLVAREGSAAPLPLYTSPSLPNITLGLPA
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KA0 TGPSAGTAGQQDAERLTLPALQQRLSLFPGTHLTPYLSTSPLERDGGAAHSPLLQHMVLL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TGPSAGTAGQQDAERLTLPALQQRLSLFPGTHLTPYLSTSPLERDGGAAHSPLLQHMVLL
              370       380       390       400       410       420

              430            440       450       460       470     
pF1KA0 EQPPAQAPLVT-----GLGALPLHAQSLVGADRVSPSIHKLRQHRPLGRTQSAPLPQNAQ
       :::::::::::     ::::::::::::::::::::::::::::::::::::::::::::
XP_011 EQPPAQAPLVTDWYLSGLGALPLHAQSLVGADRVSPSIHKLRQHRPLGRTQSAPLPQNAQ
              430       440       450       460       470       480

         480       490       500       510       520       530     
pF1KA0 ALQHLVIQQQHQQFLEKHKQQFQQQQLQMNKIIPKPSEPARQPESHPEETEEELREHQAL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ALQHLVIQQQHQQFLEKHKQQFQQQQLQMNKIIPKPSEPARQPESHPEETEEELREHQAL
              490       500       510       520       530       540

         540       550       560       570       580       590     
pF1KA0 LDEPYLDRLPGQKEAHAQAGVQVKQEPIESDEEEAEPPREVEPGQRQPSEQELLFRQQAL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LDEPYLDRLPGQKEAHAQAGVQVKQEPIESDEEEAEPPREVEPGQRQPSEQELLFRQQAL
              550       560       570       580       590       600

         600       610       620       630       640       650     
pF1KA0 LLEQQRIHQLRNYQASMEAAGIPVSFGGHRPLSRAQSSPASATFPVSVQEPPTKPRFTTG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LLEQQRIHQLRNYQASMEAAGIPVSFGGHRPLSRAQSSPASATFPVSVQEPPTKPRFTTG
              610       620       630       640       650       660

         660       670       680       690       700       710     
pF1KA0 LVYDTLMLKHQCTCGSSSSHPEHAGRIQSIWSRLQETGLRGKCECIRGRKATLEELQTVH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LVYDTLMLKHQCTCGSSSSHPEHAGRIQSIWSRLQETGLRGKCECIRGRKATLEELQTVH
              670       680       690       700       710       720

         720       730       740       750       760       770     
pF1KA0 SEAHTLLYGTNPLNRQKLDSKKLLGSLASVFVRLPCGGVGVDSDTIWNEVHSAGAARLAV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SEAHTLLYGTNPLNRQKLDSKKLLGSLASVFVRLPCGGVGVDSDTIWNEVHSAGAARLAV
              730       740       750       760       770       780

         780       790       800       810       820       830     
pF1KA0 GCVVELVFKVATGELKNGFAVVRPPGHHAEESTPMGFCYFNSVAVAAKLLQQRLSVSKIL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GCVVELVFKVATGELKNGFAVVRPPGHHAEESTPMGFCYFNSVAVAAKLLQQRLSVSKIL
              790       800       810       820       830       840

         840       850       860       870       880       890     
pF1KA0 IVDWDVHHGNGTQQAFYSDPSVLYMSLHRYDDGNFFPGSGAPDEVGTGPGVGFNVNMAFT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 IVDWDVHHGNGTQQAFYSDPSVLYMSLHRYDDGNFFPGSGAPDEVGTGPGVGFNVNMAFT
              850       860       870       880       890       900

         900       910       920       930       940       950     
pF1KA0 GGLDPPMGDAEYLAAFRTVVMPIASEFAPDVVLVSSGFDAVEGHPTPLGGYNLSARCFGY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GGLDPPMGDAEYLAAFRTVVMPIASEFAPDVVLVSSGFDAVEGHPTPLGGYNLSARCFGY
              910       920       930       940       950       960

         960       970       980       990      1000      1010     
pF1KA0 LTKQLMGLAGGRIVLALEGGHDLTAICDASEACVSALLGNELDPLPEKVLQQRPNANAVR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LTKQLMGLAGGRIVLALEGGHDLTAICDASEACVSALLGNELDPLPEKVLQQRPNANAVR
              970       980       990      1000      1010      1020

        1020      1030      1040      1050      1060      1070     
pF1KA0 SMEKVMEIHSKYWRCLQRTTSTAGRSLIEAQTCENEEAETVTAMASLSVGVKPAEKRPDE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SMEKVMEIHSKYWRCLQRTTSTAGRSLIEAQTCENEEAETVTAMASLSVGVKPAEKRPDE
             1030      1040      1050      1060      1070      1080

        1080    
pF1KA0 EPMEEEPPL
       :::::::::
XP_011 EPMEEEPPL
                

>>XP_006712941 (OMIM: 605314) PREDICTED: histone deacety  (1089 aa)
 initn: 4395 init1: 4395 opt: 7202  Z-score: 3935.6  bits: 740.0 E(85289): 1.8e-212
Smith-Waterman score: 7202; 99.5% identity (99.5% similar) in 1089 aa overlap (1-1084:1-1089)

               10        20        30        40        50        60
pF1KA0 MSSQSHPDGLSGRDQPVELLNPARVNHMPSTVDVATALPLQVAPSAVPMDLRLDHQFSLP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 MSSQSHPDGLSGRDQPVELLNPARVNHMPSTVDVATALPLQVAPSAVPMDLRLDHQFSLP
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KA0 VAEPALREQQLQQELLALKQKQQIQRQILIAEFQRQHEQLSRQHEAQLHEHIKQQQEMLA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 VAEPALREQQLQQELLALKQKQQIQRQILIAEFQRQHEQLSRQHEAQLHEHIKQQQEMLA
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KA0 MKHQQELLEHQRKLERHRQEQELEKQHREQKLQQLKNKEKGKESAVASTEVKMKLQEFVL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 MKHQQELLEHQRKLERHRQEQELEKQHREQKLQQLKNKEKGKESAVASTEVKMKLQEFVL
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KA0 NKKKALAHRNLNHCISSDPRYWYGKTQHSSLDQSSPPQSGVSTSYNHPVLGMYDAKDDFP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 NKKKALAHRNLNHCISSDPRYWYGKTQHSSLDQSSPPQSGVSTSYNHPVLGMYDAKDDFP
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KA0 LRKTASEPNLKLRSRLKQKVAERRSSPLLRRKDGPVVTALKKRPLDVTDSACSSAPGSGP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 LRKTASEPNLKLRSRLKQKVAERRSSPLLRRKDGPVVTALKKRPLDVTDSACSSAPGSGP
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KA0 SSPNNSSGSVSAENGIAPAVPSIPAETSLAHRLVAREGSAAPLPLYTSPSLPNITLGLPA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 SSPNNSSGSVSAENGIAPAVPSIPAETSLAHRLVAREGSAAPLPLYTSPSLPNITLGLPA
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KA0 TGPSAGTAGQQDAERLTLPALQQRLSLFPGTHLTPYLSTSPLERDGGAAHSPLLQHMVLL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 TGPSAGTAGQQDAERLTLPALQQRLSLFPGTHLTPYLSTSPLERDGGAAHSPLLQHMVLL
              370       380       390       400       410       420

              430            440       450       460       470     
pF1KA0 EQPPAQAPLVT-----GLGALPLHAQSLVGADRVSPSIHKLRQHRPLGRTQSAPLPQNAQ
       :::::::::::     ::::::::::::::::::::::::::::::::::::::::::::
XP_006 EQPPAQAPLVTDWYLSGLGALPLHAQSLVGADRVSPSIHKLRQHRPLGRTQSAPLPQNAQ
              430       440       450       460       470       480

         480       490       500       510       520       530     
pF1KA0 ALQHLVIQQQHQQFLEKHKQQFQQQQLQMNKIIPKPSEPARQPESHPEETEEELREHQAL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 ALQHLVIQQQHQQFLEKHKQQFQQQQLQMNKIIPKPSEPARQPESHPEETEEELREHQAL
              490       500       510       520       530       540

         540       550       560       570       580       590     
pF1KA0 LDEPYLDRLPGQKEAHAQAGVQVKQEPIESDEEEAEPPREVEPGQRQPSEQELLFRQQAL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 LDEPYLDRLPGQKEAHAQAGVQVKQEPIESDEEEAEPPREVEPGQRQPSEQELLFRQQAL
              550       560       570       580       590       600

         600       610       620       630       640       650     
pF1KA0 LLEQQRIHQLRNYQASMEAAGIPVSFGGHRPLSRAQSSPASATFPVSVQEPPTKPRFTTG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 LLEQQRIHQLRNYQASMEAAGIPVSFGGHRPLSRAQSSPASATFPVSVQEPPTKPRFTTG
              610       620       630       640       650       660

         660       670       680       690       700       710     
pF1KA0 LVYDTLMLKHQCTCGSSSSHPEHAGRIQSIWSRLQETGLRGKCECIRGRKATLEELQTVH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 LVYDTLMLKHQCTCGSSSSHPEHAGRIQSIWSRLQETGLRGKCECIRGRKATLEELQTVH
              670       680       690       700       710       720

         720       730       740       750       760       770     
pF1KA0 SEAHTLLYGTNPLNRQKLDSKKLLGSLASVFVRLPCGGVGVDSDTIWNEVHSAGAARLAV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 SEAHTLLYGTNPLNRQKLDSKKLLGSLASVFVRLPCGGVGVDSDTIWNEVHSAGAARLAV
              730       740       750       760       770       780

         780       790       800       810       820       830     
pF1KA0 GCVVELVFKVATGELKNGFAVVRPPGHHAEESTPMGFCYFNSVAVAAKLLQQRLSVSKIL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 GCVVELVFKVATGELKNGFAVVRPPGHHAEESTPMGFCYFNSVAVAAKLLQQRLSVSKIL
              790       800       810       820       830       840

         840       850       860       870       880       890     
pF1KA0 IVDWDVHHGNGTQQAFYSDPSVLYMSLHRYDDGNFFPGSGAPDEVGTGPGVGFNVNMAFT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 IVDWDVHHGNGTQQAFYSDPSVLYMSLHRYDDGNFFPGSGAPDEVGTGPGVGFNVNMAFT
              850       860       870       880       890       900

         900       910       920       930       940       950     
pF1KA0 GGLDPPMGDAEYLAAFRTVVMPIASEFAPDVVLVSSGFDAVEGHPTPLGGYNLSARCFGY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 GGLDPPMGDAEYLAAFRTVVMPIASEFAPDVVLVSSGFDAVEGHPTPLGGYNLSARCFGY
              910       920       930       940       950       960

         960       970       980       990      1000      1010     
pF1KA0 LTKQLMGLAGGRIVLALEGGHDLTAICDASEACVSALLGNELDPLPEKVLQQRPNANAVR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 LTKQLMGLAGGRIVLALEGGHDLTAICDASEACVSALLGNELDPLPEKVLQQRPNANAVR
              970       980       990      1000      1010      1020

        1020      1030      1040      1050      1060      1070     
pF1KA0 SMEKVMEIHSKYWRCLQRTTSTAGRSLIEAQTCENEEAETVTAMASLSVGVKPAEKRPDE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 SMEKVMEIHSKYWRCLQRTTSTAGRSLIEAQTCENEEAETVTAMASLSVGVKPAEKRPDE
             1030      1040      1050      1060      1070      1080

        1080    
pF1KA0 EPMEEEPPL
       :::::::::
XP_006 EPMEEEPPL
                

>>XP_011510523 (OMIM: 605314) PREDICTED: histone deacety  (1089 aa)
 initn: 4395 init1: 4395 opt: 7202  Z-score: 3935.6  bits: 740.0 E(85289): 1.8e-212
Smith-Waterman score: 7202; 99.5% identity (99.5% similar) in 1089 aa overlap (1-1084:1-1089)

               10        20        30        40        50        60
pF1KA0 MSSQSHPDGLSGRDQPVELLNPARVNHMPSTVDVATALPLQVAPSAVPMDLRLDHQFSLP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MSSQSHPDGLSGRDQPVELLNPARVNHMPSTVDVATALPLQVAPSAVPMDLRLDHQFSLP
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KA0 VAEPALREQQLQQELLALKQKQQIQRQILIAEFQRQHEQLSRQHEAQLHEHIKQQQEMLA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VAEPALREQQLQQELLALKQKQQIQRQILIAEFQRQHEQLSRQHEAQLHEHIKQQQEMLA
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KA0 MKHQQELLEHQRKLERHRQEQELEKQHREQKLQQLKNKEKGKESAVASTEVKMKLQEFVL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MKHQQELLEHQRKLERHRQEQELEKQHREQKLQQLKNKEKGKESAVASTEVKMKLQEFVL
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KA0 NKKKALAHRNLNHCISSDPRYWYGKTQHSSLDQSSPPQSGVSTSYNHPVLGMYDAKDDFP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NKKKALAHRNLNHCISSDPRYWYGKTQHSSLDQSSPPQSGVSTSYNHPVLGMYDAKDDFP
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KA0 LRKTASEPNLKLRSRLKQKVAERRSSPLLRRKDGPVVTALKKRPLDVTDSACSSAPGSGP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LRKTASEPNLKLRSRLKQKVAERRSSPLLRRKDGPVVTALKKRPLDVTDSACSSAPGSGP
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KA0 SSPNNSSGSVSAENGIAPAVPSIPAETSLAHRLVAREGSAAPLPLYTSPSLPNITLGLPA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SSPNNSSGSVSAENGIAPAVPSIPAETSLAHRLVAREGSAAPLPLYTSPSLPNITLGLPA
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KA0 TGPSAGTAGQQDAERLTLPALQQRLSLFPGTHLTPYLSTSPLERDGGAAHSPLLQHMVLL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TGPSAGTAGQQDAERLTLPALQQRLSLFPGTHLTPYLSTSPLERDGGAAHSPLLQHMVLL
              370       380       390       400       410       420

              430            440       450       460       470     
pF1KA0 EQPPAQAPLVT-----GLGALPLHAQSLVGADRVSPSIHKLRQHRPLGRTQSAPLPQNAQ
       :::::::::::     ::::::::::::::::::::::::::::::::::::::::::::
XP_011 EQPPAQAPLVTDWYLSGLGALPLHAQSLVGADRVSPSIHKLRQHRPLGRTQSAPLPQNAQ
              430       440       450       460       470       480

         480       490       500       510       520       530     
pF1KA0 ALQHLVIQQQHQQFLEKHKQQFQQQQLQMNKIIPKPSEPARQPESHPEETEEELREHQAL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ALQHLVIQQQHQQFLEKHKQQFQQQQLQMNKIIPKPSEPARQPESHPEETEEELREHQAL
              490       500       510       520       530       540

         540       550       560       570       580       590     
pF1KA0 LDEPYLDRLPGQKEAHAQAGVQVKQEPIESDEEEAEPPREVEPGQRQPSEQELLFRQQAL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LDEPYLDRLPGQKEAHAQAGVQVKQEPIESDEEEAEPPREVEPGQRQPSEQELLFRQQAL
              550       560       570       580       590       600

         600       610       620       630       640       650     
pF1KA0 LLEQQRIHQLRNYQASMEAAGIPVSFGGHRPLSRAQSSPASATFPVSVQEPPTKPRFTTG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LLEQQRIHQLRNYQASMEAAGIPVSFGGHRPLSRAQSSPASATFPVSVQEPPTKPRFTTG
              610       620       630       640       650       660

         660       670       680       690       700       710     
pF1KA0 LVYDTLMLKHQCTCGSSSSHPEHAGRIQSIWSRLQETGLRGKCECIRGRKATLEELQTVH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LVYDTLMLKHQCTCGSSSSHPEHAGRIQSIWSRLQETGLRGKCECIRGRKATLEELQTVH
              670       680       690       700       710       720

         720       730       740       750       760       770     
pF1KA0 SEAHTLLYGTNPLNRQKLDSKKLLGSLASVFVRLPCGGVGVDSDTIWNEVHSAGAARLAV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SEAHTLLYGTNPLNRQKLDSKKLLGSLASVFVRLPCGGVGVDSDTIWNEVHSAGAARLAV
              730       740       750       760       770       780

         780       790       800       810       820       830     
pF1KA0 GCVVELVFKVATGELKNGFAVVRPPGHHAEESTPMGFCYFNSVAVAAKLLQQRLSVSKIL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GCVVELVFKVATGELKNGFAVVRPPGHHAEESTPMGFCYFNSVAVAAKLLQQRLSVSKIL
              790       800       810       820       830       840

         840       850       860       870       880       890     
pF1KA0 IVDWDVHHGNGTQQAFYSDPSVLYMSLHRYDDGNFFPGSGAPDEVGTGPGVGFNVNMAFT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 IVDWDVHHGNGTQQAFYSDPSVLYMSLHRYDDGNFFPGSGAPDEVGTGPGVGFNVNMAFT
              850       860       870       880       890       900

         900       910       920       930       940       950     
pF1KA0 GGLDPPMGDAEYLAAFRTVVMPIASEFAPDVVLVSSGFDAVEGHPTPLGGYNLSARCFGY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GGLDPPMGDAEYLAAFRTVVMPIASEFAPDVVLVSSGFDAVEGHPTPLGGYNLSARCFGY
              910       920       930       940       950       960

         960       970       980       990      1000      1010     
pF1KA0 LTKQLMGLAGGRIVLALEGGHDLTAICDASEACVSALLGNELDPLPEKVLQQRPNANAVR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LTKQLMGLAGGRIVLALEGGHDLTAICDASEACVSALLGNELDPLPEKVLQQRPNANAVR
              970       980       990      1000      1010      1020

        1020      1030      1040      1050      1060      1070     
pF1KA0 SMEKVMEIHSKYWRCLQRTTSTAGRSLIEAQTCENEEAETVTAMASLSVGVKPAEKRPDE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SMEKVMEIHSKYWRCLQRTTSTAGRSLIEAQTCENEEAETVTAMASLSVGVKPAEKRPDE
             1030      1040      1050      1060      1070      1080

        1080    
pF1KA0 EPMEEEPPL
       :::::::::
XP_011 EPMEEEPPL
                

>>XP_011510524 (OMIM: 605314) PREDICTED: histone deacety  (1089 aa)
 initn: 4395 init1: 4395 opt: 7202  Z-score: 3935.6  bits: 740.0 E(85289): 1.8e-212
Smith-Waterman score: 7202; 99.5% identity (99.5% similar) in 1089 aa overlap (1-1084:1-1089)

               10        20        30        40        50        60
pF1KA0 MSSQSHPDGLSGRDQPVELLNPARVNHMPSTVDVATALPLQVAPSAVPMDLRLDHQFSLP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MSSQSHPDGLSGRDQPVELLNPARVNHMPSTVDVATALPLQVAPSAVPMDLRLDHQFSLP
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KA0 VAEPALREQQLQQELLALKQKQQIQRQILIAEFQRQHEQLSRQHEAQLHEHIKQQQEMLA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VAEPALREQQLQQELLALKQKQQIQRQILIAEFQRQHEQLSRQHEAQLHEHIKQQQEMLA
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KA0 MKHQQELLEHQRKLERHRQEQELEKQHREQKLQQLKNKEKGKESAVASTEVKMKLQEFVL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MKHQQELLEHQRKLERHRQEQELEKQHREQKLQQLKNKEKGKESAVASTEVKMKLQEFVL
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KA0 NKKKALAHRNLNHCISSDPRYWYGKTQHSSLDQSSPPQSGVSTSYNHPVLGMYDAKDDFP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NKKKALAHRNLNHCISSDPRYWYGKTQHSSLDQSSPPQSGVSTSYNHPVLGMYDAKDDFP
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KA0 LRKTASEPNLKLRSRLKQKVAERRSSPLLRRKDGPVVTALKKRPLDVTDSACSSAPGSGP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LRKTASEPNLKLRSRLKQKVAERRSSPLLRRKDGPVVTALKKRPLDVTDSACSSAPGSGP
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KA0 SSPNNSSGSVSAENGIAPAVPSIPAETSLAHRLVAREGSAAPLPLYTSPSLPNITLGLPA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SSPNNSSGSVSAENGIAPAVPSIPAETSLAHRLVAREGSAAPLPLYTSPSLPNITLGLPA
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KA0 TGPSAGTAGQQDAERLTLPALQQRLSLFPGTHLTPYLSTSPLERDGGAAHSPLLQHMVLL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TGPSAGTAGQQDAERLTLPALQQRLSLFPGTHLTPYLSTSPLERDGGAAHSPLLQHMVLL
              370       380       390       400       410       420

              430            440       450       460       470     
pF1KA0 EQPPAQAPLVT-----GLGALPLHAQSLVGADRVSPSIHKLRQHRPLGRTQSAPLPQNAQ
       :::::::::::     ::::::::::::::::::::::::::::::::::::::::::::
XP_011 EQPPAQAPLVTDWYLSGLGALPLHAQSLVGADRVSPSIHKLRQHRPLGRTQSAPLPQNAQ
              430       440       450       460       470       480

         480       490       500       510       520       530     
pF1KA0 ALQHLVIQQQHQQFLEKHKQQFQQQQLQMNKIIPKPSEPARQPESHPEETEEELREHQAL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ALQHLVIQQQHQQFLEKHKQQFQQQQLQMNKIIPKPSEPARQPESHPEETEEELREHQAL
              490       500       510       520       530       540

         540       550       560       570       580       590     
pF1KA0 LDEPYLDRLPGQKEAHAQAGVQVKQEPIESDEEEAEPPREVEPGQRQPSEQELLFRQQAL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LDEPYLDRLPGQKEAHAQAGVQVKQEPIESDEEEAEPPREVEPGQRQPSEQELLFRQQAL
              550       560       570       580       590       600

         600       610       620       630       640       650     
pF1KA0 LLEQQRIHQLRNYQASMEAAGIPVSFGGHRPLSRAQSSPASATFPVSVQEPPTKPRFTTG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LLEQQRIHQLRNYQASMEAAGIPVSFGGHRPLSRAQSSPASATFPVSVQEPPTKPRFTTG
              610       620       630       640       650       660

         660       670       680       690       700       710     
pF1KA0 LVYDTLMLKHQCTCGSSSSHPEHAGRIQSIWSRLQETGLRGKCECIRGRKATLEELQTVH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LVYDTLMLKHQCTCGSSSSHPEHAGRIQSIWSRLQETGLRGKCECIRGRKATLEELQTVH
              670       680       690       700       710       720

         720       730       740       750       760       770     
pF1KA0 SEAHTLLYGTNPLNRQKLDSKKLLGSLASVFVRLPCGGVGVDSDTIWNEVHSAGAARLAV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SEAHTLLYGTNPLNRQKLDSKKLLGSLASVFVRLPCGGVGVDSDTIWNEVHSAGAARLAV
              730       740       750       760       770       780

         780       790       800       810       820       830     
pF1KA0 GCVVELVFKVATGELKNGFAVVRPPGHHAEESTPMGFCYFNSVAVAAKLLQQRLSVSKIL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GCVVELVFKVATGELKNGFAVVRPPGHHAEESTPMGFCYFNSVAVAAKLLQQRLSVSKIL
              790       800       810       820       830       840

         840       850       860       870       880       890     
pF1KA0 IVDWDVHHGNGTQQAFYSDPSVLYMSLHRYDDGNFFPGSGAPDEVGTGPGVGFNVNMAFT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 IVDWDVHHGNGTQQAFYSDPSVLYMSLHRYDDGNFFPGSGAPDEVGTGPGVGFNVNMAFT
              850       860       870       880       890       900

         900       910       920       930       940       950     
pF1KA0 GGLDPPMGDAEYLAAFRTVVMPIASEFAPDVVLVSSGFDAVEGHPTPLGGYNLSARCFGY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GGLDPPMGDAEYLAAFRTVVMPIASEFAPDVVLVSSGFDAVEGHPTPLGGYNLSARCFGY
              910       920       930       940       950       960

         960       970       980       990      1000      1010     
pF1KA0 LTKQLMGLAGGRIVLALEGGHDLTAICDASEACVSALLGNELDPLPEKVLQQRPNANAVR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LTKQLMGLAGGRIVLALEGGHDLTAICDASEACVSALLGNELDPLPEKVLQQRPNANAVR
              970       980       990      1000      1010      1020

        1020      1030      1040      1050      1060      1070     
pF1KA0 SMEKVMEIHSKYWRCLQRTTSTAGRSLIEAQTCENEEAETVTAMASLSVGVKPAEKRPDE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SMEKVMEIHSKYWRCLQRTTSTAGRSLIEAQTCENEEAETVTAMASLSVGVKPAEKRPDE
             1030      1040      1050      1060      1070      1080

        1080    
pF1KA0 EPMEEEPPL
       :::::::::
XP_011 EPMEEEPPL
                

>>XP_011510527 (OMIM: 605314) PREDICTED: histone deacety  (1079 aa)
 initn: 7173 init1: 7173 opt: 7173  Z-score: 3919.9  bits: 737.0 E(85289): 1.3e-211
Smith-Waterman score: 7173; 100.0% identity (100.0% similar) in 1077 aa overlap (8-1084:3-1079)

               10        20        30        40        50        60
pF1KA0 MSSQSHPDGLSGRDQPVELLNPARVNHMPSTVDVATALPLQVAPSAVPMDLRLDHQFSLP
              :::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011      MFDGLSGRDQPVELLNPARVNHMPSTVDVATALPLQVAPSAVPMDLRLDHQFSLP
                    10        20        30        40        50     

               70        80        90       100       110       120
pF1KA0 VAEPALREQQLQQELLALKQKQQIQRQILIAEFQRQHEQLSRQHEAQLHEHIKQQQEMLA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VAEPALREQQLQQELLALKQKQQIQRQILIAEFQRQHEQLSRQHEAQLHEHIKQQQEMLA
          60        70        80        90       100       110     

              130       140       150       160       170       180
pF1KA0 MKHQQELLEHQRKLERHRQEQELEKQHREQKLQQLKNKEKGKESAVASTEVKMKLQEFVL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MKHQQELLEHQRKLERHRQEQELEKQHREQKLQQLKNKEKGKESAVASTEVKMKLQEFVL
         120       130       140       150       160       170     

              190       200       210       220       230       240
pF1KA0 NKKKALAHRNLNHCISSDPRYWYGKTQHSSLDQSSPPQSGVSTSYNHPVLGMYDAKDDFP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NKKKALAHRNLNHCISSDPRYWYGKTQHSSLDQSSPPQSGVSTSYNHPVLGMYDAKDDFP
         180       190       200       210       220       230     

              250       260       270       280       290       300
pF1KA0 LRKTASEPNLKLRSRLKQKVAERRSSPLLRRKDGPVVTALKKRPLDVTDSACSSAPGSGP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LRKTASEPNLKLRSRLKQKVAERRSSPLLRRKDGPVVTALKKRPLDVTDSACSSAPGSGP
         240       250       260       270       280       290     

              310       320       330       340       350       360
pF1KA0 SSPNNSSGSVSAENGIAPAVPSIPAETSLAHRLVAREGSAAPLPLYTSPSLPNITLGLPA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SSPNNSSGSVSAENGIAPAVPSIPAETSLAHRLVAREGSAAPLPLYTSPSLPNITLGLPA
         300       310       320       330       340       350     

              370       380       390       400       410       420
pF1KA0 TGPSAGTAGQQDAERLTLPALQQRLSLFPGTHLTPYLSTSPLERDGGAAHSPLLQHMVLL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TGPSAGTAGQQDAERLTLPALQQRLSLFPGTHLTPYLSTSPLERDGGAAHSPLLQHMVLL
         360       370       380       390       400       410     

              430       440       450       460       470       480
pF1KA0 EQPPAQAPLVTGLGALPLHAQSLVGADRVSPSIHKLRQHRPLGRTQSAPLPQNAQALQHL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EQPPAQAPLVTGLGALPLHAQSLVGADRVSPSIHKLRQHRPLGRTQSAPLPQNAQALQHL
         420       430       440       450       460       470     

              490       500       510       520       530       540
pF1KA0 VIQQQHQQFLEKHKQQFQQQQLQMNKIIPKPSEPARQPESHPEETEEELREHQALLDEPY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VIQQQHQQFLEKHKQQFQQQQLQMNKIIPKPSEPARQPESHPEETEEELREHQALLDEPY
         480       490       500       510       520       530     

              550       560       570       580       590       600
pF1KA0 LDRLPGQKEAHAQAGVQVKQEPIESDEEEAEPPREVEPGQRQPSEQELLFRQQALLLEQQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LDRLPGQKEAHAQAGVQVKQEPIESDEEEAEPPREVEPGQRQPSEQELLFRQQALLLEQQ
         540       550       560       570       580       590     

              610       620       630       640       650       660
pF1KA0 RIHQLRNYQASMEAAGIPVSFGGHRPLSRAQSSPASATFPVSVQEPPTKPRFTTGLVYDT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RIHQLRNYQASMEAAGIPVSFGGHRPLSRAQSSPASATFPVSVQEPPTKPRFTTGLVYDT
         600       610       620       630       640       650     

              670       680       690       700       710       720
pF1KA0 LMLKHQCTCGSSSSHPEHAGRIQSIWSRLQETGLRGKCECIRGRKATLEELQTVHSEAHT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LMLKHQCTCGSSSSHPEHAGRIQSIWSRLQETGLRGKCECIRGRKATLEELQTVHSEAHT
         660       670       680       690       700       710     

              730       740       750       760       770       780
pF1KA0 LLYGTNPLNRQKLDSKKLLGSLASVFVRLPCGGVGVDSDTIWNEVHSAGAARLAVGCVVE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LLYGTNPLNRQKLDSKKLLGSLASVFVRLPCGGVGVDSDTIWNEVHSAGAARLAVGCVVE
         720       730       740       750       760       770     

              790       800       810       820       830       840
pF1KA0 LVFKVATGELKNGFAVVRPPGHHAEESTPMGFCYFNSVAVAAKLLQQRLSVSKILIVDWD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LVFKVATGELKNGFAVVRPPGHHAEESTPMGFCYFNSVAVAAKLLQQRLSVSKILIVDWD
         780       790       800       810       820       830     

              850       860       870       880       890       900
pF1KA0 VHHGNGTQQAFYSDPSVLYMSLHRYDDGNFFPGSGAPDEVGTGPGVGFNVNMAFTGGLDP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VHHGNGTQQAFYSDPSVLYMSLHRYDDGNFFPGSGAPDEVGTGPGVGFNVNMAFTGGLDP
         840       850       860       870       880       890     

              910       920       930       940       950       960
pF1KA0 PMGDAEYLAAFRTVVMPIASEFAPDVVLVSSGFDAVEGHPTPLGGYNLSARCFGYLTKQL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PMGDAEYLAAFRTVVMPIASEFAPDVVLVSSGFDAVEGHPTPLGGYNLSARCFGYLTKQL
         900       910       920       930       940       950     

              970       980       990      1000      1010      1020
pF1KA0 MGLAGGRIVLALEGGHDLTAICDASEACVSALLGNELDPLPEKVLQQRPNANAVRSMEKV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MGLAGGRIVLALEGGHDLTAICDASEACVSALLGNELDPLPEKVLQQRPNANAVRSMEKV
         960       970       980       990      1000      1010     

             1030      1040      1050      1060      1070      1080
pF1KA0 MEIHSKYWRCLQRTTSTAGRSLIEAQTCENEEAETVTAMASLSVGVKPAEKRPDEEPMEE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MEIHSKYWRCLQRTTSTAGRSLIEAQTCENEEAETVTAMASLSVGVKPAEKRPDEEPMEE
        1020      1030      1040      1050      1060      1070     

           
pF1KA0 EPPL
       ::::
XP_011 EPPL
           

>>XP_006712940 (OMIM: 605314) PREDICTED: histone deacety  (1108 aa)
 initn: 7173 init1: 7173 opt: 7173  Z-score: 3919.7  bits: 737.1 E(85289): 1.4e-211
Smith-Waterman score: 7173; 100.0% identity (100.0% similar) in 1077 aa overlap (8-1084:32-1108)

                                      10        20        30       
pF1KA0                        MSSQSHPDGLSGRDQPVELLNPARVNHMPSTVDVATA
                                     ::::::::::::::::::::::::::::::
XP_006 NIDLCAFEIQKTSSPGYEVWFRKQYLAVDGDGLSGRDQPVELLNPARVNHMPSTVDVATA
              10        20        30        40        50        60 

        40        50        60        70        80        90       
pF1KA0 LPLQVAPSAVPMDLRLDHQFSLPVAEPALREQQLQQELLALKQKQQIQRQILIAEFQRQH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 LPLQVAPSAVPMDLRLDHQFSLPVAEPALREQQLQQELLALKQKQQIQRQILIAEFQRQH
              70        80        90       100       110       120 

       100       110       120       130       140       150       
pF1KA0 EQLSRQHEAQLHEHIKQQQEMLAMKHQQELLEHQRKLERHRQEQELEKQHREQKLQQLKN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 EQLSRQHEAQLHEHIKQQQEMLAMKHQQELLEHQRKLERHRQEQELEKQHREQKLQQLKN
             130       140       150       160       170       180 

       160       170       180       190       200       210       
pF1KA0 KEKGKESAVASTEVKMKLQEFVLNKKKALAHRNLNHCISSDPRYWYGKTQHSSLDQSSPP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 KEKGKESAVASTEVKMKLQEFVLNKKKALAHRNLNHCISSDPRYWYGKTQHSSLDQSSPP
             190       200       210       220       230       240 

       220       230       240       250       260       270       
pF1KA0 QSGVSTSYNHPVLGMYDAKDDFPLRKTASEPNLKLRSRLKQKVAERRSSPLLRRKDGPVV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 QSGVSTSYNHPVLGMYDAKDDFPLRKTASEPNLKLRSRLKQKVAERRSSPLLRRKDGPVV
             250       260       270       280       290       300 

       280       290       300       310       320       330       
pF1KA0 TALKKRPLDVTDSACSSAPGSGPSSPNNSSGSVSAENGIAPAVPSIPAETSLAHRLVARE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 TALKKRPLDVTDSACSSAPGSGPSSPNNSSGSVSAENGIAPAVPSIPAETSLAHRLVARE
             310       320       330       340       350       360 

       340       350       360       370       380       390       
pF1KA0 GSAAPLPLYTSPSLPNITLGLPATGPSAGTAGQQDAERLTLPALQQRLSLFPGTHLTPYL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 GSAAPLPLYTSPSLPNITLGLPATGPSAGTAGQQDAERLTLPALQQRLSLFPGTHLTPYL
             370       380       390       400       410       420 

       400       410       420       430       440       450       
pF1KA0 STSPLERDGGAAHSPLLQHMVLLEQPPAQAPLVTGLGALPLHAQSLVGADRVSPSIHKLR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 STSPLERDGGAAHSPLLQHMVLLEQPPAQAPLVTGLGALPLHAQSLVGADRVSPSIHKLR
             430       440       450       460       470       480 

       460       470       480       490       500       510       
pF1KA0 QHRPLGRTQSAPLPQNAQALQHLVIQQQHQQFLEKHKQQFQQQQLQMNKIIPKPSEPARQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 QHRPLGRTQSAPLPQNAQALQHLVIQQQHQQFLEKHKQQFQQQQLQMNKIIPKPSEPARQ
             490       500       510       520       530       540 

       520       530       540       550       560       570       
pF1KA0 PESHPEETEEELREHQALLDEPYLDRLPGQKEAHAQAGVQVKQEPIESDEEEAEPPREVE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 PESHPEETEEELREHQALLDEPYLDRLPGQKEAHAQAGVQVKQEPIESDEEEAEPPREVE
             550       560       570       580       590       600 

       580       590       600       610       620       630       
pF1KA0 PGQRQPSEQELLFRQQALLLEQQRIHQLRNYQASMEAAGIPVSFGGHRPLSRAQSSPASA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 PGQRQPSEQELLFRQQALLLEQQRIHQLRNYQASMEAAGIPVSFGGHRPLSRAQSSPASA
             610       620       630       640       650       660 

       640       650       660       670       680       690       
pF1KA0 TFPVSVQEPPTKPRFTTGLVYDTLMLKHQCTCGSSSSHPEHAGRIQSIWSRLQETGLRGK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 TFPVSVQEPPTKPRFTTGLVYDTLMLKHQCTCGSSSSHPEHAGRIQSIWSRLQETGLRGK
             670       680       690       700       710       720 

       700       710       720       730       740       750       
pF1KA0 CECIRGRKATLEELQTVHSEAHTLLYGTNPLNRQKLDSKKLLGSLASVFVRLPCGGVGVD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 CECIRGRKATLEELQTVHSEAHTLLYGTNPLNRQKLDSKKLLGSLASVFVRLPCGGVGVD
             730       740       750       760       770       780 

       760       770       780       790       800       810       
pF1KA0 SDTIWNEVHSAGAARLAVGCVVELVFKVATGELKNGFAVVRPPGHHAEESTPMGFCYFNS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 SDTIWNEVHSAGAARLAVGCVVELVFKVATGELKNGFAVVRPPGHHAEESTPMGFCYFNS
             790       800       810       820       830       840 

       820       830       840       850       860       870       
pF1KA0 VAVAAKLLQQRLSVSKILIVDWDVHHGNGTQQAFYSDPSVLYMSLHRYDDGNFFPGSGAP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 VAVAAKLLQQRLSVSKILIVDWDVHHGNGTQQAFYSDPSVLYMSLHRYDDGNFFPGSGAP
             850       860       870       880       890       900 

       880       890       900       910       920       930       
pF1KA0 DEVGTGPGVGFNVNMAFTGGLDPPMGDAEYLAAFRTVVMPIASEFAPDVVLVSSGFDAVE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 DEVGTGPGVGFNVNMAFTGGLDPPMGDAEYLAAFRTVVMPIASEFAPDVVLVSSGFDAVE
             910       920       930       940       950       960 

       940       950       960       970       980       990       
pF1KA0 GHPTPLGGYNLSARCFGYLTKQLMGLAGGRIVLALEGGHDLTAICDASEACVSALLGNEL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 GHPTPLGGYNLSARCFGYLTKQLMGLAGGRIVLALEGGHDLTAICDASEACVSALLGNEL
             970       980       990      1000      1010      1020 

      1000      1010      1020      1030      1040      1050       
pF1KA0 DPLPEKVLQQRPNANAVRSMEKVMEIHSKYWRCLQRTTSTAGRSLIEAQTCENEEAETVT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 DPLPEKVLQQRPNANAVRSMEKVMEIHSKYWRCLQRTTSTAGRSLIEAQTCENEEAETVT
            1030      1040      1050      1060      1070      1080 

      1060      1070      1080    
pF1KA0 AMASLSVGVKPAEKRPDEEPMEEEPPL
       :::::::::::::::::::::::::::
XP_006 AMASLSVGVKPAEKRPDEEPMEEEPPL
            1090      1100        

>>XP_011510526 (OMIM: 605314) PREDICTED: histone deacety  (1084 aa)
 initn: 4395 init1: 4395 opt: 7153  Z-score: 3909.0  bits: 735.0 E(85289): 5.4e-211
Smith-Waterman score: 7153; 99.5% identity (99.5% similar) in 1082 aa overlap (8-1084:3-1084)

               10        20        30        40        50        60
pF1KA0 MSSQSHPDGLSGRDQPVELLNPARVNHMPSTVDVATALPLQVAPSAVPMDLRLDHQFSLP
              :::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011      MFDGLSGRDQPVELLNPARVNHMPSTVDVATALPLQVAPSAVPMDLRLDHQFSLP
                    10        20        30        40        50     

               70        80        90       100       110       120
pF1KA0 VAEPALREQQLQQELLALKQKQQIQRQILIAEFQRQHEQLSRQHEAQLHEHIKQQQEMLA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VAEPALREQQLQQELLALKQKQQIQRQILIAEFQRQHEQLSRQHEAQLHEHIKQQQEMLA
          60        70        80        90       100       110     

              130       140       150       160       170       180
pF1KA0 MKHQQELLEHQRKLERHRQEQELEKQHREQKLQQLKNKEKGKESAVASTEVKMKLQEFVL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MKHQQELLEHQRKLERHRQEQELEKQHREQKLQQLKNKEKGKESAVASTEVKMKLQEFVL
         120       130       140       150       160       170     

              190       200       210       220       230       240
pF1KA0 NKKKALAHRNLNHCISSDPRYWYGKTQHSSLDQSSPPQSGVSTSYNHPVLGMYDAKDDFP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NKKKALAHRNLNHCISSDPRYWYGKTQHSSLDQSSPPQSGVSTSYNHPVLGMYDAKDDFP
         180       190       200       210       220       230     

              250       260       270       280       290       300
pF1KA0 LRKTASEPNLKLRSRLKQKVAERRSSPLLRRKDGPVVTALKKRPLDVTDSACSSAPGSGP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LRKTASEPNLKLRSRLKQKVAERRSSPLLRRKDGPVVTALKKRPLDVTDSACSSAPGSGP
         240       250       260       270       280       290     

              310       320       330       340       350       360
pF1KA0 SSPNNSSGSVSAENGIAPAVPSIPAETSLAHRLVAREGSAAPLPLYTSPSLPNITLGLPA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SSPNNSSGSVSAENGIAPAVPSIPAETSLAHRLVAREGSAAPLPLYTSPSLPNITLGLPA
         300       310       320       330       340       350     

              370       380       390       400       410       420
pF1KA0 TGPSAGTAGQQDAERLTLPALQQRLSLFPGTHLTPYLSTSPLERDGGAAHSPLLQHMVLL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TGPSAGTAGQQDAERLTLPALQQRLSLFPGTHLTPYLSTSPLERDGGAAHSPLLQHMVLL
         360       370       380       390       400       410     

              430            440       450       460       470     
pF1KA0 EQPPAQAPLVT-----GLGALPLHAQSLVGADRVSPSIHKLRQHRPLGRTQSAPLPQNAQ
       :::::::::::     ::::::::::::::::::::::::::::::::::::::::::::
XP_011 EQPPAQAPLVTDWYLSGLGALPLHAQSLVGADRVSPSIHKLRQHRPLGRTQSAPLPQNAQ
         420       430       440       450       460       470     

         480       490       500       510       520       530     
pF1KA0 ALQHLVIQQQHQQFLEKHKQQFQQQQLQMNKIIPKPSEPARQPESHPEETEEELREHQAL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ALQHLVIQQQHQQFLEKHKQQFQQQQLQMNKIIPKPSEPARQPESHPEETEEELREHQAL
         480       490       500       510       520       530     

         540       550       560       570       580       590     
pF1KA0 LDEPYLDRLPGQKEAHAQAGVQVKQEPIESDEEEAEPPREVEPGQRQPSEQELLFRQQAL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LDEPYLDRLPGQKEAHAQAGVQVKQEPIESDEEEAEPPREVEPGQRQPSEQELLFRQQAL
         540       550       560       570       580       590     

         600       610       620       630       640       650     
pF1KA0 LLEQQRIHQLRNYQASMEAAGIPVSFGGHRPLSRAQSSPASATFPVSVQEPPTKPRFTTG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LLEQQRIHQLRNYQASMEAAGIPVSFGGHRPLSRAQSSPASATFPVSVQEPPTKPRFTTG
         600       610       620       630       640       650     

         660       670       680       690       700       710     
pF1KA0 LVYDTLMLKHQCTCGSSSSHPEHAGRIQSIWSRLQETGLRGKCECIRGRKATLEELQTVH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LVYDTLMLKHQCTCGSSSSHPEHAGRIQSIWSRLQETGLRGKCECIRGRKATLEELQTVH
         660       670       680       690       700       710     

         720       730       740       750       760       770     
pF1KA0 SEAHTLLYGTNPLNRQKLDSKKLLGSLASVFVRLPCGGVGVDSDTIWNEVHSAGAARLAV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SEAHTLLYGTNPLNRQKLDSKKLLGSLASVFVRLPCGGVGVDSDTIWNEVHSAGAARLAV
         720       730       740       750       760       770     

         780       790       800       810       820       830     
pF1KA0 GCVVELVFKVATGELKNGFAVVRPPGHHAEESTPMGFCYFNSVAVAAKLLQQRLSVSKIL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GCVVELVFKVATGELKNGFAVVRPPGHHAEESTPMGFCYFNSVAVAAKLLQQRLSVSKIL
         780       790       800       810       820       830     

         840       850       860       870       880       890     
pF1KA0 IVDWDVHHGNGTQQAFYSDPSVLYMSLHRYDDGNFFPGSGAPDEVGTGPGVGFNVNMAFT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 IVDWDVHHGNGTQQAFYSDPSVLYMSLHRYDDGNFFPGSGAPDEVGTGPGVGFNVNMAFT
         840       850       860       870       880       890     

         900       910       920       930       940       950     
pF1KA0 GGLDPPMGDAEYLAAFRTVVMPIASEFAPDVVLVSSGFDAVEGHPTPLGGYNLSARCFGY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GGLDPPMGDAEYLAAFRTVVMPIASEFAPDVVLVSSGFDAVEGHPTPLGGYNLSARCFGY
         900       910       920       930       940       950     

         960       970       980       990      1000      1010     
pF1KA0 LTKQLMGLAGGRIVLALEGGHDLTAICDASEACVSALLGNELDPLPEKVLQQRPNANAVR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LTKQLMGLAGGRIVLALEGGHDLTAICDASEACVSALLGNELDPLPEKVLQQRPNANAVR
         960       970       980       990      1000      1010     

        1020      1030      1040      1050      1060      1070     
pF1KA0 SMEKVMEIHSKYWRCLQRTTSTAGRSLIEAQTCENEEAETVTAMASLSVGVKPAEKRPDE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SMEKVMEIHSKYWRCLQRTTSTAGRSLIEAQTCENEEAETVTAMASLSVGVKPAEKRPDE
        1020      1030      1040      1050      1060      1070     

        1080    
pF1KA0 EPMEEEPPL
       :::::::::
XP_011 EPMEEEPPL
        1080    

>>XP_011510522 (OMIM: 605314) PREDICTED: histone deacety  (1090 aa)
 initn: 4395 init1: 4395 opt: 7153  Z-score: 3909.0  bits: 735.0 E(85289): 5.4e-211
Smith-Waterman score: 7153; 99.5% identity (99.5% similar) in 1082 aa overlap (8-1084:9-1090)

                10        20        30        40        50         
pF1KA0  MSSQSHPDGLSGRDQPVELLNPARVNHMPSTVDVATALPLQVAPSAVPMDLRLDHQFSL
               ::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MRKLGPREDGLSGRDQPVELLNPARVNHMPSTVDVATALPLQVAPSAVPMDLRLDHQFSL
               10        20        30        40        50        60

      60        70        80        90       100       110         
pF1KA0 PVAEPALREQQLQQELLALKQKQQIQRQILIAEFQRQHEQLSRQHEAQLHEHIKQQQEML
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PVAEPALREQQLQQELLALKQKQQIQRQILIAEFQRQHEQLSRQHEAQLHEHIKQQQEML
               70        80        90       100       110       120

     120       130       140       150       160       170         
pF1KA0 AMKHQQELLEHQRKLERHRQEQELEKQHREQKLQQLKNKEKGKESAVASTEVKMKLQEFV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AMKHQQELLEHQRKLERHRQEQELEKQHREQKLQQLKNKEKGKESAVASTEVKMKLQEFV
              130       140       150       160       170       180

     180       190       200       210       220       230         
pF1KA0 LNKKKALAHRNLNHCISSDPRYWYGKTQHSSLDQSSPPQSGVSTSYNHPVLGMYDAKDDF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LNKKKALAHRNLNHCISSDPRYWYGKTQHSSLDQSSPPQSGVSTSYNHPVLGMYDAKDDF
              190       200       210       220       230       240

     240       250       260       270       280       290         
pF1KA0 PLRKTASEPNLKLRSRLKQKVAERRSSPLLRRKDGPVVTALKKRPLDVTDSACSSAPGSG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PLRKTASEPNLKLRSRLKQKVAERRSSPLLRRKDGPVVTALKKRPLDVTDSACSSAPGSG
              250       260       270       280       290       300

     300       310       320       330       340       350         
pF1KA0 PSSPNNSSGSVSAENGIAPAVPSIPAETSLAHRLVAREGSAAPLPLYTSPSLPNITLGLP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PSSPNNSSGSVSAENGIAPAVPSIPAETSLAHRLVAREGSAAPLPLYTSPSLPNITLGLP
              310       320       330       340       350       360

     360       370       380       390       400       410         
pF1KA0 ATGPSAGTAGQQDAERLTLPALQQRLSLFPGTHLTPYLSTSPLERDGGAAHSPLLQHMVL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ATGPSAGTAGQQDAERLTLPALQQRLSLFPGTHLTPYLSTSPLERDGGAAHSPLLQHMVL
              370       380       390       400       410       420

     420       430            440       450       460       470    
pF1KA0 LEQPPAQAPLVT-----GLGALPLHAQSLVGADRVSPSIHKLRQHRPLGRTQSAPLPQNA
       ::::::::::::     :::::::::::::::::::::::::::::::::::::::::::
XP_011 LEQPPAQAPLVTDWYLSGLGALPLHAQSLVGADRVSPSIHKLRQHRPLGRTQSAPLPQNA
              430       440       450       460       470       480

          480       490       500       510       520       530    
pF1KA0 QALQHLVIQQQHQQFLEKHKQQFQQQQLQMNKIIPKPSEPARQPESHPEETEEELREHQA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QALQHLVIQQQHQQFLEKHKQQFQQQQLQMNKIIPKPSEPARQPESHPEETEEELREHQA
              490       500       510       520       530       540

          540       550       560       570       580       590    
pF1KA0 LLDEPYLDRLPGQKEAHAQAGVQVKQEPIESDEEEAEPPREVEPGQRQPSEQELLFRQQA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LLDEPYLDRLPGQKEAHAQAGVQVKQEPIESDEEEAEPPREVEPGQRQPSEQELLFRQQA
              550       560       570       580       590       600

          600       610       620       630       640       650    
pF1KA0 LLLEQQRIHQLRNYQASMEAAGIPVSFGGHRPLSRAQSSPASATFPVSVQEPPTKPRFTT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LLLEQQRIHQLRNYQASMEAAGIPVSFGGHRPLSRAQSSPASATFPVSVQEPPTKPRFTT
              610       620       630       640       650       660

          660       670       680       690       700       710    
pF1KA0 GLVYDTLMLKHQCTCGSSSSHPEHAGRIQSIWSRLQETGLRGKCECIRGRKATLEELQTV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GLVYDTLMLKHQCTCGSSSSHPEHAGRIQSIWSRLQETGLRGKCECIRGRKATLEELQTV
              670       680       690       700       710       720

          720       730       740       750       760       770    
pF1KA0 HSEAHTLLYGTNPLNRQKLDSKKLLGSLASVFVRLPCGGVGVDSDTIWNEVHSAGAARLA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 HSEAHTLLYGTNPLNRQKLDSKKLLGSLASVFVRLPCGGVGVDSDTIWNEVHSAGAARLA
              730       740       750       760       770       780

          780       790       800       810       820       830    
pF1KA0 VGCVVELVFKVATGELKNGFAVVRPPGHHAEESTPMGFCYFNSVAVAAKLLQQRLSVSKI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VGCVVELVFKVATGELKNGFAVVRPPGHHAEESTPMGFCYFNSVAVAAKLLQQRLSVSKI
              790       800       810       820       830       840

          840       850       860       870       880       890    
pF1KA0 LIVDWDVHHGNGTQQAFYSDPSVLYMSLHRYDDGNFFPGSGAPDEVGTGPGVGFNVNMAF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LIVDWDVHHGNGTQQAFYSDPSVLYMSLHRYDDGNFFPGSGAPDEVGTGPGVGFNVNMAF
              850       860       870       880       890       900

          900       910       920       930       940       950    
pF1KA0 TGGLDPPMGDAEYLAAFRTVVMPIASEFAPDVVLVSSGFDAVEGHPTPLGGYNLSARCFG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TGGLDPPMGDAEYLAAFRTVVMPIASEFAPDVVLVSSGFDAVEGHPTPLGGYNLSARCFG
              910       920       930       940       950       960

          960       970       980       990      1000      1010    
pF1KA0 YLTKQLMGLAGGRIVLALEGGHDLTAICDASEACVSALLGNELDPLPEKVLQQRPNANAV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 YLTKQLMGLAGGRIVLALEGGHDLTAICDASEACVSALLGNELDPLPEKVLQQRPNANAV
              970       980       990      1000      1010      1020

         1020      1030      1040      1050      1060      1070    
pF1KA0 RSMEKVMEIHSKYWRCLQRTTSTAGRSLIEAQTCENEEAETVTAMASLSVGVKPAEKRPD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RSMEKVMEIHSKYWRCLQRTTSTAGRSLIEAQTCENEEAETVTAMASLSVGVKPAEKRPD
             1030      1040      1050      1060      1070      1080

         1080    
pF1KA0 EEPMEEEPPL
       ::::::::::
XP_011 EEPMEEEPPL
             1090

>>XP_011510519 (OMIM: 605314) PREDICTED: histone deacety  (1113 aa)
 initn: 4395 init1: 4395 opt: 7153  Z-score: 3908.8  bits: 735.0 E(85289): 5.5e-211
Smith-Waterman score: 7153; 99.5% identity (99.5% similar) in 1082 aa overlap (8-1084:32-1113)

                                      10        20        30       
pF1KA0                        MSSQSHPDGLSGRDQPVELLNPARVNHMPSTVDVATA
                                     ::::::::::::::::::::::::::::::
XP_011 NIDLCAFEIQKTSSPGYEVWFRKQYLAVDGDGLSGRDQPVELLNPARVNHMPSTVDVATA
              10        20        30        40        50        60 

        40        50        60        70        80        90       
pF1KA0 LPLQVAPSAVPMDLRLDHQFSLPVAEPALREQQLQQELLALKQKQQIQRQILIAEFQRQH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LPLQVAPSAVPMDLRLDHQFSLPVAEPALREQQLQQELLALKQKQQIQRQILIAEFQRQH
              70        80        90       100       110       120 

       100       110       120       130       140       150       
pF1KA0 EQLSRQHEAQLHEHIKQQQEMLAMKHQQELLEHQRKLERHRQEQELEKQHREQKLQQLKN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EQLSRQHEAQLHEHIKQQQEMLAMKHQQELLEHQRKLERHRQEQELEKQHREQKLQQLKN
             130       140       150       160       170       180 

       160       170       180       190       200       210       
pF1KA0 KEKGKESAVASTEVKMKLQEFVLNKKKALAHRNLNHCISSDPRYWYGKTQHSSLDQSSPP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KEKGKESAVASTEVKMKLQEFVLNKKKALAHRNLNHCISSDPRYWYGKTQHSSLDQSSPP
             190       200       210       220       230       240 

       220       230       240       250       260       270       
pF1KA0 QSGVSTSYNHPVLGMYDAKDDFPLRKTASEPNLKLRSRLKQKVAERRSSPLLRRKDGPVV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QSGVSTSYNHPVLGMYDAKDDFPLRKTASEPNLKLRSRLKQKVAERRSSPLLRRKDGPVV
             250       260       270       280       290       300 

       280       290       300       310       320       330       
pF1KA0 TALKKRPLDVTDSACSSAPGSGPSSPNNSSGSVSAENGIAPAVPSIPAETSLAHRLVARE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TALKKRPLDVTDSACSSAPGSGPSSPNNSSGSVSAENGIAPAVPSIPAETSLAHRLVARE
             310       320       330       340       350       360 

       340       350       360       370       380       390       
pF1KA0 GSAAPLPLYTSPSLPNITLGLPATGPSAGTAGQQDAERLTLPALQQRLSLFPGTHLTPYL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GSAAPLPLYTSPSLPNITLGLPATGPSAGTAGQQDAERLTLPALQQRLSLFPGTHLTPYL
             370       380       390       400       410       420 

       400       410       420       430            440       450  
pF1KA0 STSPLERDGGAAHSPLLQHMVLLEQPPAQAPLVT-----GLGALPLHAQSLVGADRVSPS
       ::::::::::::::::::::::::::::::::::     :::::::::::::::::::::
XP_011 STSPLERDGGAAHSPLLQHMVLLEQPPAQAPLVTDWYLSGLGALPLHAQSLVGADRVSPS
             430       440       450       460       470       480 

            460       470       480       490       500       510  
pF1KA0 IHKLRQHRPLGRTQSAPLPQNAQALQHLVIQQQHQQFLEKHKQQFQQQQLQMNKIIPKPS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 IHKLRQHRPLGRTQSAPLPQNAQALQHLVIQQQHQQFLEKHKQQFQQQQLQMNKIIPKPS
             490       500       510       520       530       540 

            520       530       540       550       560       570  
pF1KA0 EPARQPESHPEETEEELREHQALLDEPYLDRLPGQKEAHAQAGVQVKQEPIESDEEEAEP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EPARQPESHPEETEEELREHQALLDEPYLDRLPGQKEAHAQAGVQVKQEPIESDEEEAEP
             550       560       570       580       590       600 

            580       590       600       610       620       630  
pF1KA0 PREVEPGQRQPSEQELLFRQQALLLEQQRIHQLRNYQASMEAAGIPVSFGGHRPLSRAQS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PREVEPGQRQPSEQELLFRQQALLLEQQRIHQLRNYQASMEAAGIPVSFGGHRPLSRAQS
             610       620       630       640       650       660 

            640       650       660       670       680       690  
pF1KA0 SPASATFPVSVQEPPTKPRFTTGLVYDTLMLKHQCTCGSSSSHPEHAGRIQSIWSRLQET
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SPASATFPVSVQEPPTKPRFTTGLVYDTLMLKHQCTCGSSSSHPEHAGRIQSIWSRLQET
             670       680       690       700       710       720 

            700       710       720       730       740       750  
pF1KA0 GLRGKCECIRGRKATLEELQTVHSEAHTLLYGTNPLNRQKLDSKKLLGSLASVFVRLPCG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GLRGKCECIRGRKATLEELQTVHSEAHTLLYGTNPLNRQKLDSKKLLGSLASVFVRLPCG
             730       740       750       760       770       780 

            760       770       780       790       800       810  
pF1KA0 GVGVDSDTIWNEVHSAGAARLAVGCVVELVFKVATGELKNGFAVVRPPGHHAEESTPMGF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GVGVDSDTIWNEVHSAGAARLAVGCVVELVFKVATGELKNGFAVVRPPGHHAEESTPMGF
             790       800       810       820       830       840 

            820       830       840       850       860       870  
pF1KA0 CYFNSVAVAAKLLQQRLSVSKILIVDWDVHHGNGTQQAFYSDPSVLYMSLHRYDDGNFFP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 CYFNSVAVAAKLLQQRLSVSKILIVDWDVHHGNGTQQAFYSDPSVLYMSLHRYDDGNFFP
             850       860       870       880       890       900 

            880       890       900       910       920       930  
pF1KA0 GSGAPDEVGTGPGVGFNVNMAFTGGLDPPMGDAEYLAAFRTVVMPIASEFAPDVVLVSSG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GSGAPDEVGTGPGVGFNVNMAFTGGLDPPMGDAEYLAAFRTVVMPIASEFAPDVVLVSSG
             910       920       930       940       950       960 

            940       950       960       970       980       990  
pF1KA0 FDAVEGHPTPLGGYNLSARCFGYLTKQLMGLAGGRIVLALEGGHDLTAICDASEACVSAL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FDAVEGHPTPLGGYNLSARCFGYLTKQLMGLAGGRIVLALEGGHDLTAICDASEACVSAL
             970       980       990      1000      1010      1020 

           1000      1010      1020      1030      1040      1050  
pF1KA0 LGNELDPLPEKVLQQRPNANAVRSMEKVMEIHSKYWRCLQRTTSTAGRSLIEAQTCENEE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LGNELDPLPEKVLQQRPNANAVRSMEKVMEIHSKYWRCLQRTTSTAGRSLIEAQTCENEE
            1030      1040      1050      1060      1070      1080 

           1060      1070      1080    
pF1KA0 AETVTAMASLSVGVKPAEKRPDEEPMEEEPPL
       ::::::::::::::::::::::::::::::::
XP_011 AETVTAMASLSVGVKPAEKRPDEEPMEEEPPL
            1090      1100      1110   




1084 residues in 1 query   sequences
60827320 residues in 85289 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Thu Nov  3 19:38:08 2016 done: Thu Nov  3 19:38:10 2016
 Total Scan time: 17.320 Total Display time:  0.500

Function used was FASTA [36.3.4 Apr, 2011]
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