Result of FASTA (omim) for pF1KB5642
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KB5642, 350 aa
  1>>>pF1KB5642 350 - 350 aa - 350 aa
Library: /omim/omim.rfq.tfa
  60827320 residues in 85289 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 7.6634+/-0.000308; mu= 7.0255+/- 0.019
 mean_var=161.8662+/-32.482, 0's: 0 Z-trim(121.6): 33  B-trim: 0 in 0/55
 Lambda= 0.100808
 statistics sampled from 38477 (38512) to 38477 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.78), E-opt: 0.2 (0.452), width:  16
 Scan time:  9.630

The best scores are:                                      opt bits E(85289)
NP_068779 (OMIM: 159552) induced myeloid leukemia  ( 350) 2292 344.7 1.8e-94
NP_877495 (OMIM: 159552) induced myeloid leukemia  ( 271) 1507 230.4 3.5e-60
NP_001184249 (OMIM: 159552) induced myeloid leukem ( 197) 1052 164.1 2.3e-40
XP_016882566 (OMIM: 600040) PREDICTED: apoptosis r ( 173)  201 40.3  0.0037
NP_620116 (OMIM: 600040) apoptosis regulator BAX i ( 192)  201 40.4   0.004
NP_001179 (OMIM: 600516) bcl-2 homologous antagoni ( 211)  196 39.7  0.0072
XP_011513081 (OMIM: 600516) PREDICTED: bcl-2 homol ( 211)  196 39.7  0.0072


>>NP_068779 (OMIM: 159552) induced myeloid leukemia cell  (350 aa)
 initn: 2292 init1: 2292 opt: 2292  Z-score: 1816.9  bits: 344.7 E(85289): 1.8e-94
Smith-Waterman score: 2292; 100.0% identity (100.0% similar) in 350 aa overlap (1-350:1-350)

               10        20        30        40        50        60
pF1KB5 MFGLKRNAVIGLNLYCGGAGLGAGSGGATRPGGRLLATEKEASARREIGGGEAGAVIGGS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_068 MFGLKRNAVIGLNLYCGGAGLGAGSGGATRPGGRLLATEKEASARREIGGGEAGAVIGGS
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB5 AGASPPSTLTPDSRRVARPPPIGAEVPDVTATPARLLFFAPTRRAAPLEEMEAPAADAIM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_068 AGASPPSTLTPDSRRVARPPPIGAEVPDVTATPARLLFFAPTRRAAPLEEMEAPAADAIM
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB5 SPEEELDGYEPEPLGKRPAVLPLLELVGESGNNTSTDGSLPSTPPPAEEEEDELYRQSLE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_068 SPEEELDGYEPEPLGKRPAVLPLLELVGESGNNTSTDGSLPSTPPPAEEEEDELYRQSLE
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB5 IISRYLREQATGAKDTKPMGRSGATSRKALETLRRVGDGVQRNHETAFQGMLRKLDIKNE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_068 IISRYLREQATGAKDTKPMGRSGATSRKALETLRRVGDGVQRNHETAFQGMLRKLDIKNE
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB5 DDVKSLSRVMIHVFSDGVTNWGRIVTLISFGAFVAKHLKTINQESCIEPLAESITDVLVR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_068 DDVKSLSRVMIHVFSDGVTNWGRIVTLISFGAFVAKHLKTINQESCIEPLAESITDVLVR
              250       260       270       280       290       300

              310       320       330       340       350
pF1KB5 TKRDWLVKQRGWDGFVEFFHVEDLEGGIRNVLLAFAGVAGVGAGLAYLIR
       ::::::::::::::::::::::::::::::::::::::::::::::::::
NP_068 TKRDWLVKQRGWDGFVEFFHVEDLEGGIRNVLLAFAGVAGVGAGLAYLIR
              310       320       330       340       350

>>NP_877495 (OMIM: 159552) induced myeloid leukemia cell  (271 aa)
 initn: 1507 init1: 1507 opt: 1507  Z-score: 1201.4  bits: 230.4 E(85289): 3.5e-60
Smith-Waterman score: 1507; 100.0% identity (100.0% similar) in 230 aa overlap (1-230:1-230)

               10        20        30        40        50        60
pF1KB5 MFGLKRNAVIGLNLYCGGAGLGAGSGGATRPGGRLLATEKEASARREIGGGEAGAVIGGS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_877 MFGLKRNAVIGLNLYCGGAGLGAGSGGATRPGGRLLATEKEASARREIGGGEAGAVIGGS
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB5 AGASPPSTLTPDSRRVARPPPIGAEVPDVTATPARLLFFAPTRRAAPLEEMEAPAADAIM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_877 AGASPPSTLTPDSRRVARPPPIGAEVPDVTATPARLLFFAPTRRAAPLEEMEAPAADAIM
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB5 SPEEELDGYEPEPLGKRPAVLPLLELVGESGNNTSTDGSLPSTPPPAEEEEDELYRQSLE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_877 SPEEELDGYEPEPLGKRPAVLPLLELVGESGNNTSTDGSLPSTPPPAEEEEDELYRQSLE
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB5 IISRYLREQATGAKDTKPMGRSGATSRKALETLRRVGDGVQRNHETAFQGMLRKLDIKNE
       ::::::::::::::::::::::::::::::::::::::::::::::::::          
NP_877 IISRYLREQATGAKDTKPMGRSGATSRKALETLRRVGDGVQRNHETAFQGWVCGVLPCRG
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB5 DDVKSLSRVMIHVFSDGVTNWGRIVTLISFGAFVAKHLKTINQESCIEPLAESITDVLVR
                                                                   
NP_877 PRRWHQECAAGFCRCCWSRSWFGISNKIALL                             
              250       260       270                              

>>NP_001184249 (OMIM: 159552) induced myeloid leukemia c  (197 aa)
 initn: 1050 init1: 1050 opt: 1052  Z-score: 845.7  bits: 164.1 E(85289): 2.3e-40
Smith-Waterman score: 1052; 98.8% identity (98.8% similar) in 164 aa overlap (187-350:34-197)

        160       170       180       190       200       210      
pF1KB5 DGSLPSTPPPAEEEEDELYRQSLEIISRYLREQATGAKDTKPMGRSGATSRKALETLRRV
                                     :  :::::::::::::::::::::::::::
NP_001 LKRNAVIGLNLYCGGAGLGAGSGGATRPGGRLLATGAKDTKPMGRSGATSRKALETLRRV
            10        20        30        40        50        60   

        220       230       240       250       260       270      
pF1KB5 GDGVQRNHETAFQGMLRKLDIKNEDDVKSLSRVMIHVFSDGVTNWGRIVTLISFGAFVAK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GDGVQRNHETAFQGMLRKLDIKNEDDVKSLSRVMIHVFSDGVTNWGRIVTLISFGAFVAK
            70        80        90       100       110       120   

        280       290       300       310       320       330      
pF1KB5 HLKTINQESCIEPLAESITDVLVRTKRDWLVKQRGWDGFVEFFHVEDLEGGIRNVLLAFA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 HLKTINQESCIEPLAESITDVLVRTKRDWLVKQRGWDGFVEFFHVEDLEGGIRNVLLAFA
           130       140       150       160       170       180   

        340       350
pF1KB5 GVAGVGAGLAYLIR
       ::::::::::::::
NP_001 GVAGVGAGLAYLIR
           190       

>--
 initn: 228 init1: 228 opt: 228  Z-score: 198.1  bits: 44.3 E(85289): 0.00027
Smith-Waterman score: 228; 100.0% identity (100.0% similar) in 33 aa overlap (1-33:1-33)

               10        20        30        40        50        60
pF1KB5 MFGLKRNAVIGLNLYCGGAGLGAGSGGATRPGGRLLATEKEASARREIGGGEAGAVIGGS
       :::::::::::::::::::::::::::::::::                           
NP_001 MFGLKRNAVIGLNLYCGGAGLGAGSGGATRPGGRLLATGAKDTKPMGRSGATSRKALETL
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB5 AGASPPSTLTPDSRRVARPPPIGAEVPDVTATPARLLFFAPTRRAAPLEEMEAPAADAIM
                                                                   
NP_001 RRVGDGVQRNHETAFQGMLRKLDIKNEDDVKSLSRVMIHVFSDGVTNWGRIVTLISFGAF
               70        80        90       100       110       120

>>XP_016882566 (OMIM: 600040) PREDICTED: apoptosis regul  (173 aa)
 initn: 156 init1: 138 opt: 201  Z-score: 177.6  bits: 40.3 E(85289): 0.0037
Smith-Waterman score: 201; 35.0% identity (58.1% similar) in 117 aa overlap (204-319:35-146)

           180       190       200       210       220       230   
pF1KB5 LYRQSLEIISRYLREQATGAKDTKPMGRSGATSRKALETLRRVGDGVQRNHETAFQGMLR
                                     :...:  : :.:.:: .. : :  .: :. 
XP_016 ALLLQGFIQDRAGRMGGEAPELALDPVPQDASTKKLSECLKRIGDELDSNME--LQRMIA
           10        20        30        40        50          60  

           240       250       260       270        280       290  
pF1KB5 KLDIKNEDDVKSLSRVMIHVFSDGVTNWGRIVTLISFGA-FVAKHLKTINQESCIEPLAE
        .:  .  .:  . ::   .::::  ::::.:.:. :.. .: : : :   :  :. .  
XP_016 AVDTDSPREV--FFRVAADMFSDGNFNWGRVVALFYFASKLVLKALCTKVPE-LIRTIMG
             70          80        90       100       110          

            300       310       320       330       340       350
pF1KB5 SITDVLVRTKRDWLVKQRGWDGFVEFFHVEDLEGGIRNVLLAFAGVAGVGAGLAYLIR
          : : .    :.  : ::::.. .:                               
XP_016 WTLDFLRERLLGWIQDQGGWDGLLSYFGTPTWQTVTIFVAGVLTASLTIWKKMG    
     120       130       140       150       160       170       

>>NP_620116 (OMIM: 600040) apoptosis regulator BAX isofo  (192 aa)
 initn: 179 init1: 138 opt: 201  Z-score: 177.0  bits: 40.4 E(85289): 0.004
Smith-Waterman score: 201; 35.0% identity (58.1% similar) in 117 aa overlap (204-319:54-165)

           180       190       200       210       220       230   
pF1KB5 LYRQSLEIISRYLREQATGAKDTKPMGRSGATSRKALETLRRVGDGVQRNHETAFQGMLR
                                     :...:  : :.:.:: .. : :  .: :. 
NP_620 ALLLQGFIQDRAGRMGGEAPELALDPVPQDASTKKLSECLKRIGDELDSNME--LQRMIA
            30        40        50        60        70          80 

           240       250       260       270        280       290  
pF1KB5 KLDIKNEDDVKSLSRVMIHVFSDGVTNWGRIVTLISFGA-FVAKHLKTINQESCIEPLAE
        .:  .  .:  . ::   .::::  ::::.:.:. :.. .: : : :   :  :. .  
NP_620 AVDTDSPREV--FFRVAADMFSDGNFNWGRVVALFYFASKLVLKALCTKVPE-LIRTIMG
              90         100       110       120       130         

            300       310       320       330       340       350
pF1KB5 SITDVLVRTKRDWLVKQRGWDGFVEFFHVEDLEGGIRNVLLAFAGVAGVGAGLAYLIR
          : : .    :.  : ::::.. .:                               
NP_620 WTLDFLRERLLGWIQDQGGWDGLLSYFGTPTWQTVTIFVAGVLTASLTIWKKMG    
      140       150       160       170       180       190      

>>NP_001179 (OMIM: 600516) bcl-2 homologous antagonist/k  (211 aa)
 initn: 152 init1:  86 opt: 196  Z-score: 172.5  bits: 39.7 E(85289): 0.0072
Smith-Waterman score: 196; 26.3% identity (58.8% similar) in 194 aa overlap (161-342:17-201)

              140       150       160       170           180      
pF1KB5 PEPLGKRPAVLPLLELVGESGNNTSTDGSLPSTPPPAEEE----EDELYRQSLEIISRYL
                                     :. :  .::.     .:..:.   .. :. 
NP_001               MASGQGPGPPRQECGEPALPSASEEQVAQDTEEVFRS--YVFYRHQ
                             10        20        30          40    

         190              200       210       220       230        
pF1KB5 REQ-ATGAKD-------TKPMGRSGATSRKALETLRRVGDGVQRNHETAFQGMLRKLDIK
       .:: : :.         : :.  : .:  .. . :  .:: ..: ... :: ::..:.  
NP_001 QEQEAEGVAAPADPEMVTLPLQPS-STMGQVGRQLAIIGDDINRRYDSEFQTMLQHLQPT
           50        60         70        80        90       100   

      240       250       260       270       280       290        
pF1KB5 NEDDVKSLSRVMIHVFSDGVTNWGRIVTLISFGAFVAKHLKTINQESCIEPLAESITDVL
        :.  . ....   .: .:. ::::.:.:..::  .: :.   .  . .  ... ..: .
NP_001 AENAYEYFTKIATSLFESGI-NWGRVVALLGFGYRLALHVYQHGLTGFLGQVTRFVVDFM
           110       120        130       140       150       160  

      300       310       320       330       340       350  
pF1KB5 VRTKRDWLVKQRGWDGFVEFFHVEDLEGGIRNVLLAFAGVAGVGAGLAYLIR  
       ..      . :::  :.:  ... .  : : :::... ::. .:          
NP_001 LHHCIARWIAQRG--GWVAALNLGN--GPILNVLVVL-GVVLLGQFVVRRFFKS
            170         180         190        200       210 

>>XP_011513081 (OMIM: 600516) PREDICTED: bcl-2 homologou  (211 aa)
 initn: 152 init1:  86 opt: 196  Z-score: 172.5  bits: 39.7 E(85289): 0.0072
Smith-Waterman score: 196; 26.3% identity (58.8% similar) in 194 aa overlap (161-342:17-201)

              140       150       160       170           180      
pF1KB5 PEPLGKRPAVLPLLELVGESGNNTSTDGSLPSTPPPAEEE----EDELYRQSLEIISRYL
                                     :. :  .::.     .:..:.   .. :. 
XP_011               MASGQGPGPPRQECGEPALPSASEEQVAQDTEEVFRS--YVFYRHQ
                             10        20        30          40    

         190              200       210       220       230        
pF1KB5 REQ-ATGAKD-------TKPMGRSGATSRKALETLRRVGDGVQRNHETAFQGMLRKLDIK
       .:: : :.         : :.  : .:  .. . :  .:: ..: ... :: ::..:.  
XP_011 QEQEAEGVAAPADPEMVTLPLQPS-STMGQVGRQLAIIGDDINRRYDSEFQTMLQHLQPT
           50        60         70        80        90       100   

      240       250       260       270       280       290        
pF1KB5 NEDDVKSLSRVMIHVFSDGVTNWGRIVTLISFGAFVAKHLKTINQESCIEPLAESITDVL
        :.  . ....   .: .:. ::::.:.:..::  .: :.   .  . .  ... ..: .
XP_011 AENAYEYFTKIATSLFESGI-NWGRVVALLGFGYRLALHVYQHGLTGFLGQVTRFVVDFM
           110       120        130       140       150       160  

      300       310       320       330       340       350  
pF1KB5 VRTKRDWLVKQRGWDGFVEFFHVEDLEGGIRNVLLAFAGVAGVGAGLAYLIR  
       ..      . :::  :.:  ... .  : : :::... ::. .:          
XP_011 LHHCIARWIAQRG--GWVAALNLGN--GPILNVLVVL-GVVLLGQFVVRRFFKS
            170         180         190        200       210 




350 residues in 1 query   sequences
60827320 residues in 85289 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Thu Nov  3 17:50:20 2016 done: Thu Nov  3 17:50:21 2016
 Total Scan time:  9.630 Total Display time:  0.000

Function used was FASTA [36.3.4 Apr, 2011]
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