Result of FASTA (omim) for
pF1KB5159
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB5159, 196 aa
1>>>pF1KB5159 196 - 196 aa - 196 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.2774+/-0.000403; mu= 13.7374+/- 0.025
mean_var=84.1060+/-17.087, 0's: 0 Z-trim(114.3): 398 B-trim: 1230 in 2/49
Lambda= 0.139849
statistics sampled from 23596 (24096) to 23596 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.676), E-opt: 0.2 (0.283), width: 16
Scan time: 5.820
The best scores are: opt bits E(85289)
NP_004031 (OMIM: 165370) rho-related GTP-binding p ( 196) 1324 276.6 1.8e-74
NP_001300870 (OMIM: 165390) transforming protein R ( 193) 1122 235.9 3.2e-62
NP_001655 (OMIM: 165390) transforming protein RhoA ( 193) 1122 235.9 3.2e-62
NP_001036144 (OMIM: 165380) rho-related GTP-bindin ( 193) 1114 234.2 9.8e-62
NP_001036143 (OMIM: 165380) rho-related GTP-bindin ( 193) 1114 234.2 9.8e-62
NP_786886 (OMIM: 165380) rho-related GTP-binding p ( 193) 1114 234.2 9.8e-62
NP_001300872 (OMIM: 165390) transforming protein R ( 187) 902 191.5 7.2e-49
NP_001300873 (OMIM: 165390) transforming protein R ( 173) 711 152.9 2.7e-37
NP_008839 (OMIM: 602048) ras-related C3 botulinum ( 192) 704 151.5 7.8e-37
NP_036381 (OMIM: 605857) rho-related GTP-binding p ( 205) 689 148.5 6.7e-36
NP_005043 (OMIM: 602050) ras-related C3 botulinum ( 192) 687 148.1 8.4e-36
NP_002863 (OMIM: 602049,608203) ras-related C3 bot ( 192) 684 147.5 1.3e-35
XP_005252973 (OMIM: 179505) PREDICTED: rho-related ( 191) 674 145.5 5.2e-35
XP_016873208 (OMIM: 179505) PREDICTED: rho-related ( 191) 674 145.5 5.2e-35
NP_001656 (OMIM: 179505) rho-related GTP-binding p ( 191) 674 145.5 5.2e-35
NP_001782 (OMIM: 116952,616737) cell division cont ( 191) 661 142.8 3.2e-34
NP_001034891 (OMIM: 116952,616737) cell division c ( 191) 661 142.8 3.2e-34
NP_426359 (OMIM: 116952,616737) cell division cont ( 191) 660 142.6 3.7e-34
NP_055393 (OMIM: 605781) rho-related GTP-binding p ( 210) 659 142.5 4.5e-34
NP_001241667 (OMIM: 602924) rho-related GTP-bindin ( 244) 643 139.3 4.7e-33
NP_005159 (OMIM: 602924) rho-related GTP-binding p ( 244) 643 139.3 4.7e-33
NP_065714 (OMIM: 607653) rho-related GTP-binding p ( 214) 622 135.0 8.1e-32
NP_005431 (OMIM: 601555) rho-related GTP-binding p ( 227) 609 132.4 5.2e-31
XP_011523618 (OMIM: 601555) PREDICTED: rho-related ( 234) 609 132.4 5.3e-31
NP_001303236 (OMIM: 602050) ras-related C3 botulin ( 170) 598 130.1 2e-30
XP_006724349 (OMIM: 602049,608203) PREDICTED: ras- ( 161) 594 129.3 3.3e-30
NP_067028 (OMIM: 606366) rho-related GTP-binding p ( 258) 593 129.2 5.4e-30
NP_001300874 (OMIM: 165390) transforming protein R ( 112) 588 127.9 5.8e-30
XP_016859205 (OMIM: 605857) PREDICTED: rho-related ( 172) 578 126.1 3.2e-29
XP_011531028 (OMIM: 605857) PREDICTED: rho-related ( 192) 578 126.1 3.5e-29
NP_055285 (OMIM: 609038) rho-related GTP-binding p ( 232) 543 119.1 5.4e-27
XP_006720277 (OMIM: 607653) PREDICTED: rho-related ( 176) 536 117.6 1.2e-26
NP_001265292 (OMIM: 602037) rho-related GTP-bindin ( 191) 507 111.8 7.2e-25
NP_001265297 (OMIM: 602037) rho-related GTP-bindin ( 191) 507 111.8 7.2e-25
XP_016863678 (OMIM: 602037) PREDICTED: rho-related ( 191) 507 111.8 7.2e-25
NP_004301 (OMIM: 602037) rho-related GTP-binding p ( 191) 507 111.8 7.2e-25
NP_001265289 (OMIM: 602037) rho-related GTP-bindin ( 191) 507 111.8 7.2e-25
NP_001265291 (OMIM: 602037) rho-related GTP-bindin ( 191) 507 111.8 7.2e-25
NP_001265296 (OMIM: 602037) rho-related GTP-bindin ( 191) 507 111.8 7.2e-25
NP_001265298 (OMIM: 602037) rho-related GTP-bindin ( 191) 507 111.8 7.2e-25
XP_016863677 (OMIM: 602037) PREDICTED: rho-related ( 191) 507 111.8 7.2e-25
XP_011511994 (OMIM: 602037) PREDICTED: rho-related ( 191) 507 111.8 7.2e-25
NP_001265294 (OMIM: 602037) rho-related GTP-bindin ( 191) 507 111.8 7.2e-25
NP_001265290 (OMIM: 602037) rho-related GTP-bindin ( 191) 507 111.8 7.2e-25
NP_001265288 (OMIM: 602037) rho-related GTP-bindin ( 191) 507 111.8 7.2e-25
NP_001265295 (OMIM: 602037) rho-related GTP-bindin ( 191) 507 111.8 7.2e-25
NP_001265293 (OMIM: 602037) rho-related GTP-bindin ( 191) 507 111.8 7.2e-25
XP_011523619 (OMIM: 601555) PREDICTED: rho-related ( 206) 493 109.0 5.4e-24
XP_011531030 (OMIM: 605857) PREDICTED: rho-related ( 157) 454 101.0 1e-21
NP_061485 (OMIM: 602048) ras-related C3 botulinum ( 211) 357 81.6 1e-15
>>NP_004031 (OMIM: 165370) rho-related GTP-binding prote (196 aa)
initn: 1324 init1: 1324 opt: 1324 Z-score: 1458.2 bits: 276.6 E(85289): 1.8e-74
Smith-Waterman score: 1324; 100.0% identity (100.0% similar) in 196 aa overlap (1-196:1-196)
10 20 30 40 50 60
pF1KB5 MAAIRKKLVVVGDGACGKTCLLIVFSKDEFPEVYVPTVFENYVADIEVDGKQVELALWDT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 MAAIRKKLVVVGDGACGKTCLLIVFSKDEFPEVYVPTVFENYVADIEVDGKQVELALWDT
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB5 AGQEDYDRLRPLSYPDTDVILMCFSVDSPDSLENIPEKWVPEVKHFCPNVPIILVANKKD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 AGQEDYDRLRPLSYPDTDVILMCFSVDSPDSLENIPEKWVPEVKHFCPNVPIILVANKKD
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB5 LRSDEHVRTELARMKQEPVRTDDGRAMAVRIQAYDYLECSAKTKEGVREVFETATRAALQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 LRSDEHVRTELARMKQEPVRTDDGRAMAVRIQAYDYLECSAKTKEGVREVFETATRAALQ
130 140 150 160 170 180
190
pF1KB5 KRYGSQNGCINCCKVL
::::::::::::::::
NP_004 KRYGSQNGCINCCKVL
190
>>NP_001300870 (OMIM: 165390) transforming protein RhoA (193 aa)
initn: 1130 init1: 1110 opt: 1122 Z-score: 1238.0 bits: 235.9 E(85289): 3.2e-62
Smith-Waterman score: 1122; 85.3% identity (94.8% similar) in 191 aa overlap (1-190:1-191)
10 20 30 40 50 60
pF1KB5 MAAIRKKLVVVGDGACGKTCLLIVFSKDEFPEVYVPTVFENYVADIEVDGKQVELALWDT
:::::::::.::::::::::::::::::.:::::::::::::::::::::::::::::::
NP_001 MAAIRKKLVIVGDGACGKTCLLIVFSKDQFPEVYVPTVFENYVADIEVDGKQVELALWDT
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB5 AGQEDYDRLRPLSYPDTDVILMCFSVDSPDSLENIPEKWVPEVKHFCPNVPIILVANKKD
:::::::::::::::::::::::::.:::::::::::::.:::::::::::::::.::::
NP_001 AGQEDYDRLRPLSYPDTDVILMCFSIDSPDSLENIPEKWTPEVKHFCPNVPIILVGNKKD
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB5 LRSDEHVRTELARMKQEPVRTDDGRAMAVRIQAYDYLECSAKTKEGVREVFETATRAALQ
::.:::.: :::.::::::. ..:: :: :: :. :.:::::::.::::::: :::::::
NP_001 LRNDEHTRRELAKMKQEPVKPEEGRDMANRIGAFGYMECSAKTKDGVREVFEMATRAALQ
130 140 150 160 170 180
190
pF1KB5 KRYGSQ-NGCINCCKVL
: :.. .::.
NP_001 ARRGKKKSGCLVL
190
>>NP_001655 (OMIM: 165390) transforming protein RhoA iso (193 aa)
initn: 1130 init1: 1110 opt: 1122 Z-score: 1238.0 bits: 235.9 E(85289): 3.2e-62
Smith-Waterman score: 1122; 85.3% identity (94.8% similar) in 191 aa overlap (1-190:1-191)
10 20 30 40 50 60
pF1KB5 MAAIRKKLVVVGDGACGKTCLLIVFSKDEFPEVYVPTVFENYVADIEVDGKQVELALWDT
:::::::::.::::::::::::::::::.:::::::::::::::::::::::::::::::
NP_001 MAAIRKKLVIVGDGACGKTCLLIVFSKDQFPEVYVPTVFENYVADIEVDGKQVELALWDT
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB5 AGQEDYDRLRPLSYPDTDVILMCFSVDSPDSLENIPEKWVPEVKHFCPNVPIILVANKKD
:::::::::::::::::::::::::.:::::::::::::.:::::::::::::::.::::
NP_001 AGQEDYDRLRPLSYPDTDVILMCFSIDSPDSLENIPEKWTPEVKHFCPNVPIILVGNKKD
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB5 LRSDEHVRTELARMKQEPVRTDDGRAMAVRIQAYDYLECSAKTKEGVREVFETATRAALQ
::.:::.: :::.::::::. ..:: :: :: :. :.:::::::.::::::: :::::::
NP_001 LRNDEHTRRELAKMKQEPVKPEEGRDMANRIGAFGYMECSAKTKDGVREVFEMATRAALQ
130 140 150 160 170 180
190
pF1KB5 KRYGSQ-NGCINCCKVL
: :.. .::.
NP_001 ARRGKKKSGCLVL
190
>>NP_001036144 (OMIM: 165380) rho-related GTP-binding pr (193 aa)
initn: 1127 init1: 1107 opt: 1114 Z-score: 1229.3 bits: 234.2 E(85289): 9.8e-62
Smith-Waterman score: 1114; 85.8% identity (95.3% similar) in 190 aa overlap (1-189:1-190)
10 20 30 40 50 60
pF1KB5 MAAIRKKLVVVGDGACGKTCLLIVFSKDEFPEVYVPTVFENYVADIEVDGKQVELALWDT
:::::::::.::::::::::::::::::.:::::::::::::.:::::::::::::::::
NP_001 MAAIRKKLVIVGDGACGKTCLLIVFSKDQFPEVYVPTVFENYIADIEVDGKQVELALWDT
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB5 AGQEDYDRLRPLSYPDTDVILMCFSVDSPDSLENIPEKWVPEVKHFCPNVPIILVANKKD
:::::::::::::::::::::::::.:::::::::::::.:::::::::::::::.::::
NP_001 AGQEDYDRLRPLSYPDTDVILMCFSIDSPDSLENIPEKWTPEVKHFCPNVPIILVGNKKD
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB5 LRSDEHVRTELARMKQEPVRTDDGRAMAVRIQAYDYLECSAKTKEGVREVFETATRAALQ
::.:::.: :::.:::::::...:: :: ::.:. ::::::::::::::::: ::::.::
NP_001 LRQDEHTRRELAKMKQEPVRSEEGRDMANRISAFGYLECSAKTKEGVREVFEMATRAGLQ
130 140 150 160 170 180
190
pF1KB5 KRYGSQN-GCINCCKVL
: ... ::
NP_001 VRKNKRRRGCPIL
190
>>NP_001036143 (OMIM: 165380) rho-related GTP-binding pr (193 aa)
initn: 1127 init1: 1107 opt: 1114 Z-score: 1229.3 bits: 234.2 E(85289): 9.8e-62
Smith-Waterman score: 1114; 85.8% identity (95.3% similar) in 190 aa overlap (1-189:1-190)
10 20 30 40 50 60
pF1KB5 MAAIRKKLVVVGDGACGKTCLLIVFSKDEFPEVYVPTVFENYVADIEVDGKQVELALWDT
:::::::::.::::::::::::::::::.:::::::::::::.:::::::::::::::::
NP_001 MAAIRKKLVIVGDGACGKTCLLIVFSKDQFPEVYVPTVFENYIADIEVDGKQVELALWDT
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB5 AGQEDYDRLRPLSYPDTDVILMCFSVDSPDSLENIPEKWVPEVKHFCPNVPIILVANKKD
:::::::::::::::::::::::::.:::::::::::::.:::::::::::::::.::::
NP_001 AGQEDYDRLRPLSYPDTDVILMCFSIDSPDSLENIPEKWTPEVKHFCPNVPIILVGNKKD
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB5 LRSDEHVRTELARMKQEPVRTDDGRAMAVRIQAYDYLECSAKTKEGVREVFETATRAALQ
::.:::.: :::.:::::::...:: :: ::.:. ::::::::::::::::: ::::.::
NP_001 LRQDEHTRRELAKMKQEPVRSEEGRDMANRISAFGYLECSAKTKEGVREVFEMATRAGLQ
130 140 150 160 170 180
190
pF1KB5 KRYGSQN-GCINCCKVL
: ... ::
NP_001 VRKNKRRRGCPIL
190
>>NP_786886 (OMIM: 165380) rho-related GTP-binding prote (193 aa)
initn: 1127 init1: 1107 opt: 1114 Z-score: 1229.3 bits: 234.2 E(85289): 9.8e-62
Smith-Waterman score: 1114; 85.8% identity (95.3% similar) in 190 aa overlap (1-189:1-190)
10 20 30 40 50 60
pF1KB5 MAAIRKKLVVVGDGACGKTCLLIVFSKDEFPEVYVPTVFENYVADIEVDGKQVELALWDT
:::::::::.::::::::::::::::::.:::::::::::::.:::::::::::::::::
NP_786 MAAIRKKLVIVGDGACGKTCLLIVFSKDQFPEVYVPTVFENYIADIEVDGKQVELALWDT
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB5 AGQEDYDRLRPLSYPDTDVILMCFSVDSPDSLENIPEKWVPEVKHFCPNVPIILVANKKD
:::::::::::::::::::::::::.:::::::::::::.:::::::::::::::.::::
NP_786 AGQEDYDRLRPLSYPDTDVILMCFSIDSPDSLENIPEKWTPEVKHFCPNVPIILVGNKKD
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB5 LRSDEHVRTELARMKQEPVRTDDGRAMAVRIQAYDYLECSAKTKEGVREVFETATRAALQ
::.:::.: :::.:::::::...:: :: ::.:. ::::::::::::::::: ::::.::
NP_786 LRQDEHTRRELAKMKQEPVRSEEGRDMANRISAFGYLECSAKTKEGVREVFEMATRAGLQ
130 140 150 160 170 180
190
pF1KB5 KRYGSQN-GCINCCKVL
: ... ::
NP_786 VRKNKRRRGCPIL
190
>>NP_001300872 (OMIM: 165390) transforming protein RhoA (187 aa)
initn: 916 init1: 902 opt: 902 Z-score: 998.3 bits: 191.5 E(85289): 7.2e-49
Smith-Waterman score: 902; 93.5% identity (99.3% similar) in 138 aa overlap (1-138:1-138)
10 20 30 40 50 60
pF1KB5 MAAIRKKLVVVGDGACGKTCLLIVFSKDEFPEVYVPTVFENYVADIEVDGKQVELALWDT
:::::::::.::::::::::::::::::.:::::::::::::::::::::::::::::::
NP_001 MAAIRKKLVIVGDGACGKTCLLIVFSKDQFPEVYVPTVFENYVADIEVDGKQVELALWDT
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB5 AGQEDYDRLRPLSYPDTDVILMCFSVDSPDSLENIPEKWVPEVKHFCPNVPIILVANKKD
:::::::::::::::::::::::::.:::::::::::::.:::::::::::::::.::::
NP_001 AGQEDYDRLRPLSYPDTDVILMCFSIDSPDSLENIPEKWTPEVKHFCPNVPIILVGNKKD
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB5 LRSDEHVRTELARMKQEPVRTDDGRAMAVRIQAYDYLECSAKTKEGVREVFETATRAALQ
::.:::.: :::.:::::
NP_001 LRNDEHTRRELAKMKQEPHCVARLECCGTILAQLQPPPPRFKRFPCLSLLSSWGYRRPLP
130 140 150 160 170 180
>>NP_001300873 (OMIM: 165390) transforming protein RhoA (173 aa)
initn: 972 init1: 699 opt: 711 Z-score: 790.5 bits: 152.9 E(85289): 2.7e-37
Smith-Waterman score: 940; 74.9% identity (84.3% similar) in 191 aa overlap (1-190:1-171)
10 20 30 40 50 60
pF1KB5 MAAIRKKLVVVGDGACGKTCLLIVFSKDEFPEVYVPTVFENYVADIEVDGKQVELALWDT
:::::::::.::::::::::::::::::.::::::::::::::
NP_001 MAAIRKKLVIVGDGACGKTCLLIVFSKDQFPEVYVPTVFENYV-----------------
10 20 30 40
70 80 90 100 110 120
pF1KB5 AGQEDYDRLRPLSYPDTDVILMCFSVDSPDSLENIPEKWVPEVKHFCPNVPIILVANKKD
::::::::::::::::::::::.:::::::::::::.:::::::::::::::.::::
NP_001 ---EDYDRLRPLSYPDTDVILMCFSIDSPDSLENIPEKWTPEVKHFCPNVPIILVGNKKD
50 60 70 80 90 100
130 140 150 160 170 180
pF1KB5 LRSDEHVRTELARMKQEPVRTDDGRAMAVRIQAYDYLECSAKTKEGVREVFETATRAALQ
::.:::.: :::.::::::. ..:: :: :: :. :.:::::::.::::::: :::::::
NP_001 LRNDEHTRRELAKMKQEPVKPEEGRDMANRIGAFGYMECSAKTKDGVREVFEMATRAALQ
110 120 130 140 150 160
190
pF1KB5 KRYGSQ-NGCINCCKVL
: :.. .::.
NP_001 ARRGKKKSGCLVL
170
>>NP_008839 (OMIM: 602048) ras-related C3 botulinum toxi (192 aa)
initn: 727 init1: 698 opt: 704 Z-score: 782.3 bits: 151.5 E(85289): 7.8e-37
Smith-Waterman score: 704; 59.8% identity (78.2% similar) in 179 aa overlap (1-179:1-177)
10 20 30 40 50 60
pF1KB5 MAAIRKKLVVVGDGACGKTCLLIVFSKDEFPEVYVPTVFENYVADIEVDGKQVELALWDT
: :: : ::::::: ::::::: .. . :: :.::::.:: :.. :::: :.:.::::
NP_008 MQAI--KCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVDGKPVNLGLWDT
10 20 30 40 50
70 80 90 100 110 120
pF1KB5 AGQEDYDRLRPLSYPDTDVILMCFSVDSPDSLENIPEKWVPEVKHFCPNVPIILVANKKD
:::::::::::::::.:::.:.:::. :: :.::. :: :::.: :::.:::::..: :
NP_008 AGQEDYDRLRPLSYPQTDVFLICFSLVSPASFENVRAKWYPEVRHHCPNTPIILVGTKLD
60 70 80 90 100 110
130 140 150 160 170 180
pF1KB5 LRSDEHVRTELARMKQEPVRTDDGRAMAVRIQAYDYLECSAKTKEGVREVFETATRAALQ
::.:. . .: . : :. .: ::: .: : :::::: :..:.. ::. : ::.:
NP_008 LRDDKDTIEKLKEKKLTPITYPQGLAMAKEIGAVKYLECSALTQRGLKTVFDEAIRAVLC
120 130 140 150 160 170
190
pF1KB5 KRYGSQNGCINCCKVL
NP_008 PPPVKKRKRKCLLL
180 190
>>NP_036381 (OMIM: 605857) rho-related GTP-binding prote (205 aa)
initn: 699 init1: 637 opt: 689 Z-score: 765.5 bits: 148.5 E(85289): 6.7e-36
Smith-Waterman score: 689; 52.0% identity (78.0% similar) in 200 aa overlap (3-195:7-204)
10 20 30 40 50
pF1KB5 MAAIRKKLVVVGDGACGKTCLLIVFSKDEFPEVYVPTVFENYVADIEVDGKQVELA
:. : ::::::: ::::::. ...: ::: ::::::..:.... : ::: :.
NP_036 MAHGPGALMLKCVVVGDGAVGKTCLLMSYANDAFPEEYVPTVFDHYAVSVTVGGKQYLLG
10 20 30 40 50 60
60 70 80 90 100 110
pF1KB5 LWDTAGQEDYDRLRPLSYPDTDVILMCFSVDSPDSLENIPEKWVPEVKHFCPNVPIILVA
:.::::::::::::::::: :::.:.:::: .: :..:. :.::::.:.. ::::..:..
NP_036 LYDTAGQEDYDRLRPLSYPMTDVFLICFSVVNPASFQNVKEEWVPELKEYAPNVPFLLIG
70 80 90 100 110 120
120 130 140 150 160 170
pF1KB5 NKKDLRSDEHVRTELARMKQEPVRTDDGRAMAVRIQAYDYLECSAKTKEGVREVFETATR
.. :::.: .. ..: ::..:. ...:. .: .: : :.:::: :..:.. ::. :
NP_036 TQIDLRDDPKTLARLNDMKEKPICVEQGQKLAKEIGACCYVECSALTQKGLKTVFDEAII
130 140 150 160 170 180
180 190
pF1KB5 AAL-------QKRYGSQNGCINCCKVL
: : .:: ::. ::::: .
NP_036 AILTPKKHTVKKRIGSR--CINCCLIT
190 200
196 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Thu Nov 3 16:13:36 2016 done: Thu Nov 3 16:13:37 2016
Total Scan time: 5.820 Total Display time: 0.000
Function used was FASTA [36.3.4 Apr, 2011]