Result of FASTA (omim) for pF1KB5096
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KB5096, 582 aa
  1>>>pF1KB5096 582 - 582 aa - 582 aa
Library: /omim/omim.rfq.tfa
  60827320 residues in 85289 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 6.1845+/-0.00034; mu= 14.9641+/- 0.021
 mean_var=89.6337+/-17.920, 0's: 0 Z-trim(117.4): 70  B-trim: 321 in 1/55
 Lambda= 0.135469
 statistics sampled from 29316 (29387) to 29316 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.706), E-opt: 0.2 (0.345), width:  16
 Scan time: 10.700

The best scores are:                                      opt bits E(85289)
NP_004986 (OMIM: 277950,600754) matrix metalloprot ( 582) 4072 806.0       0
NP_071913 (OMIM: 608482) matrix metalloproteinase- ( 562) 1255 255.4 3.7e-67
NP_005932 (OMIM: 602262) matrix metalloproteinase- ( 607) 1158 236.4   2e-61
XP_011526802 (OMIM: 604871) PREDICTED: matrix meta ( 556) 1134 231.7 4.8e-60
NP_057239 (OMIM: 602285) matrix metalloproteinase- ( 603) 1134 231.8 5.1e-60
XP_016883086 (OMIM: 604871) PREDICTED: matrix meta ( 591) 1130 231.0 8.7e-60
XP_016883087 (OMIM: 604871) PREDICTED: matrix meta ( 614) 1130 231.0   9e-60
NP_006681 (OMIM: 604871) matrix metalloproteinase- ( 645) 1130 231.0 9.3e-60
XP_011520904 (OMIM: 608482) PREDICTED: matrix meta ( 528) 1106 226.3   2e-58
XP_011520906 (OMIM: 608482) PREDICTED: matrix meta ( 478) 1095 224.1 8.3e-58
NP_002419 (OMIM: 602261) matrix metalloproteinase- ( 669) 1071 219.5 2.8e-56
XP_011536658 (OMIM: 602285) PREDICTED: matrix meta ( 519) 1005 206.5 1.8e-52
XP_011536659 (OMIM: 602285) PREDICTED: matrix meta ( 519) 1005 206.5 1.8e-52
XP_011536657 (OMIM: 602285) PREDICTED: matrix meta ( 519) 1005 206.5 1.8e-52
NP_005931 (OMIM: 185261) stromelysin-3 preproprote ( 488)  906 187.1 1.1e-46
XP_016874796 (OMIM: 602285) PREDICTED: matrix meta ( 434)  875 181.1 6.7e-45
XP_011520907 (OMIM: 608482) PREDICTED: matrix meta ( 352)  847 175.5 2.5e-43
NP_077278 (OMIM: 608417) matrix metalloproteinase- ( 520)  747 156.1 2.7e-37
NP_004762 (OMIM: 604629,612529) matrix metalloprot ( 483)  734 153.5 1.5e-36
XP_011523528 (OMIM: 608417) PREDICTED: matrix meta ( 435)  671 141.2 6.8e-33
XP_011523530 (OMIM: 608417) PREDICTED: matrix meta ( 435)  671 141.2 6.8e-33
XP_011523531 (OMIM: 608417) PREDICTED: matrix meta ( 435)  671 141.2 6.8e-33
XP_011523529 (OMIM: 608417) PREDICTED: matrix meta ( 435)  671 141.2 6.8e-33
NP_002420 (OMIM: 601807,611543) matrix metalloprot ( 508)  633 133.8 1.3e-30
XP_011523527 (OMIM: 608417) PREDICTED: matrix meta ( 445)  607 128.7   4e-29
NP_002413 (OMIM: 185250,614466) stromelysin-1 prep ( 477)  549 117.4 1.1e-25
XP_006719464 (OMIM: 601807,611543) PREDICTED: matr ( 279)  543 116.1 1.6e-25
NP_002416 (OMIM: 185260) stromelysin-2 preproprote ( 476)  544 116.4 2.2e-25
XP_011523532 (OMIM: 608417) PREDICTED: matrix meta ( 418)  539 115.4 3.8e-25
XP_011523533 (OMIM: 608417) PREDICTED: matrix meta ( 390)  531 113.8 1.1e-24
NP_116568 (OMIM: 608417) matrix metalloproteinase- ( 393)  531 113.8 1.1e-24
XP_016879050 (OMIM: 608482) PREDICTED: matrix meta ( 287)  510 109.6 1.4e-23
NP_002418 (OMIM: 250400,600108,602111) collagenase ( 471)  496 107.0 1.4e-22
NP_001289439 (OMIM: 120360,259600) 72 kDa type IV  ( 584)  494 106.7 2.2e-22
NP_001289438 (OMIM: 120360,259600) 72 kDa type IV  ( 584)  494 106.7 2.2e-22
NP_001289437 (OMIM: 120360,259600) 72 kDa type IV  ( 584)  494 106.7 2.2e-22
NP_001121363 (OMIM: 120360,259600) 72 kDa type IV  ( 610)  494 106.7 2.3e-22
NP_004521 (OMIM: 120360,259600) 72 kDa type IV col ( 660)  494 106.7 2.5e-22
NP_001139410 (OMIM: 120353,226600,606963) intersti ( 403)  487 105.2 4.3e-22
NP_002412 (OMIM: 120353,226600,606963) interstitia ( 469)  487 105.2 4.8e-22
NP_002414 (OMIM: 178990) matrilysin preproprotein  ( 267)  479 103.6 8.9e-22
XP_011536661 (OMIM: 601807,611543) PREDICTED: matr ( 426)  480 103.9 1.2e-21
NP_002417 (OMIM: 601046) macrophage metalloelastas ( 470)  467 101.3 7.3e-21
XP_011541138 (OMIM: 120355) PREDICTED: neutrophil  ( 377)  445 97.0 1.2e-19
XP_016873260 (OMIM: 120355) PREDICTED: neutrophil  ( 444)  445 97.0 1.4e-19
NP_001291370 (OMIM: 120355) neutrophil collagenase ( 444)  445 97.0 1.4e-19
XP_011541137 (OMIM: 120355) PREDICTED: neutrophil  ( 444)  445 97.0 1.4e-19
NP_001291371 (OMIM: 120355) neutrophil collagenase ( 444)  445 97.0 1.4e-19
NP_002415 (OMIM: 120355) neutrophil collagenase is ( 467)  445 97.0 1.4e-19
XP_011541136 (OMIM: 120355) PREDICTED: neutrophil  ( 476)  445 97.0 1.4e-19


>>NP_004986 (OMIM: 277950,600754) matrix metalloproteina  (582 aa)
 initn: 4072 init1: 4072 opt: 4072  Z-score: 4301.9  bits: 806.0 E(85289):    0
Smith-Waterman score: 4072; 100.0% identity (100.0% similar) in 582 aa overlap (1-582:1-582)

               10        20        30        40        50        60
pF1KB5 MSPAPRPPRCLLLPLLTLGTALASLGSAQSSSFSPEAWLQQYGYLPPGDLRTHTQRSPQS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 MSPAPRPPRCLLLPLLTLGTALASLGSAQSSSFSPEAWLQQYGYLPPGDLRTHTQRSPQS
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB5 LSAAIAAMQKFYGLQVTGKADADTMKAMRRPRCGVPDKFGAEIKANVRRKRYAIQGLKWQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 LSAAIAAMQKFYGLQVTGKADADTMKAMRRPRCGVPDKFGAEIKANVRRKRYAIQGLKWQ
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB5 HNEITFCIQNYTPKVGEYATYEAIRKAFRVWESATPLRFREVPYAYIREGHEKQADIMIF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 HNEITFCIQNYTPKVGEYATYEAIRKAFRVWESATPLRFREVPYAYIREGHEKQADIMIF
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB5 FAEGFHGDSTPFDGEGGFLAHAYFPGPNIGGDTHFDSAEPWTVRNEDLNGNDIFLVAVHE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 FAEGFHGDSTPFDGEGGFLAHAYFPGPNIGGDTHFDSAEPWTVRNEDLNGNDIFLVAVHE
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB5 LGHALGLEHSSDPSAIMAPFYQWMDTENFVLPDDDRRGIQQLYGGESGFPTKMPPQPRTT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 LGHALGLEHSSDPSAIMAPFYQWMDTENFVLPDDDRRGIQQLYGGESGFPTKMPPQPRTT
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KB5 SRPSVPDKPKNPTYGPNICDGNFDTVAMLRGEMFVFKERWFWRVRNNQVMDGYPMPIGQF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 SRPSVPDKPKNPTYGPNICDGNFDTVAMLRGEMFVFKERWFWRVRNNQVMDGYPMPIGQF
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KB5 WRGLPASINTAYERKDGKFVFFKGDKHWVFDEASLEPGYPKHIKELGRGLPTDKIDAALF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 WRGLPASINTAYERKDGKFVFFKGDKHWVFDEASLEPGYPKHIKELGRGLPTDKIDAALF
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KB5 WMPNGKTYFFRGNKYYRFNEELRAVDSEYPKNIKVWEGIPESPRGSFMGSDEVFTYFYKG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 WMPNGKTYFFRGNKYYRFNEELRAVDSEYPKNIKVWEGIPESPRGSFMGSDEVFTYFYKG
              430       440       450       460       470       480

              490       500       510       520       530       540
pF1KB5 NKYWKFNNQKLKVEPGYPKSALRDWMGCPSGGRPDEGTEEETEVIIIEVDEEGGGAVSAA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 NKYWKFNNQKLKVEPGYPKSALRDWMGCPSGGRPDEGTEEETEVIIIEVDEEGGGAVSAA
              490       500       510       520       530       540

              550       560       570       580  
pF1KB5 AVVLPVLLLLLVLAVGLAVFFFRRHGTPRRLLYCQRSLLDKV
       ::::::::::::::::::::::::::::::::::::::::::
NP_004 AVVLPVLLLLLVLAVGLAVFFFRRHGTPRRLLYCQRSLLDKV
              550       560       570       580  

>>NP_071913 (OMIM: 608482) matrix metalloproteinase-25 p  (562 aa)
 initn: 1174 init1: 245 opt: 1255  Z-score: 1326.7  bits: 255.4 E(85289): 3.7e-67
Smith-Waterman score: 1336; 40.6% identity (65.0% similar) in 566 aa overlap (12-556:10-557)

               10        20        30        40        50        60
pF1KB5 MSPAPRPPRCLLLPLLTLGTALASLGSAQSSSFSPEAWLQQYGYLPPGDLRTHTQRSPQS
                  :: ::    : :   :::. :.. . :: .::::::        .::..
NP_071   MRLRLRLLALLLLLLAPPARAPKPSAQDVSLGVD-WLTRYGYLPPPHPAQAQLQSPEK
                 10        20        30         40        50       

               70        80        90       100       110       120
pF1KB5 LSAAIAAMQKFYGLQVTGKADADTMKAMRRPRCGVPDKFGAEIKANVRRKRYAIQGLKWQ
       :  :: .::.: ::  ::. :  :. .::.:::..:: .:.   .  ::.:::..:  :.
NP_071 LRDAIKVMQRFAGLPETGRMDPGTVATMRKPRCSLPDVLGVAGLVR-RRRRYALSGSVWK
        60        70        80        90       100        110      

              130       140           150       160       170      
pF1KB5 HNEITFCIQNYTPKVGEYATYEAIR----KAFRVWESATPLRFREVPYAYIREGHEKQAD
       .  .:. .... :. ..  . :..:     :. .:   . : :.::      .:.:   :
NP_071 KRTLTWRVRSF-PQSSQL-SQETVRVLMSYALMAWGMESGLTFHEVDSP---QGQE--PD
        120        130        140       150       160              

        180       190       200        210       220       230     
pF1KB5 IMIFFAEGFHGDSTPFDGEGGFLAHAYFPGPN-IGGDTHFDSAEPWTVRNEDLNGNDIFL
       :.: ::..:: :: :::: :: ::::.::: . :.::::::. : ::  ..: .:.:.: 
NP_071 ILIDFARAFHQDSYPFDGLGGTLAHAFFPGEHPISGDTHFDDEETWTFGSKDGEGTDLFA
     170       180       190       200       210       220         

         240       250       260         270       280       290   
pF1KB5 VAVHELGHALGLEHSSDPSAIMAPFYQWM--DTENFVLPDDDRRGIQQLYGGESGFPTKM
       :::::.:::::: ::: :..:: ::::    : ... : .::: :.:::::     :   
NP_071 VAVHEFGHALGLGHSSAPNSIMRPFYQGPVGDPDKYRLSQDDRDGLQQLYGKAPQTPYDK
     230       240       250       260       270       280         

           300        310        320       330       340        350
pF1KB5 PPQPRTTSRPSVPDKP-KNPTYG-PNICDGNFDTVAMLRGEMFVFKERWFWRVR-NNQVM
       : .   .  :. : .: ..:..  :. :.::::..: .::: : ::  ::::.. ..:..
NP_071 PTRKPLAPPPQPPASPTHSPSFPIPDRCEGNFDAIANIRGETFFFKGPWFWRLQPSGQLV
     290       300       310       320       330       340         

              360          370        380       390       400      
pF1KB5 DGYPMPIGQFWRGLPASI---NTAYER-KDGKFVFFKGDKHWVFDEASLEPGYPKHIKEL
       .  :  . .::.::::..   ..:: : .::....:.: . :::.. .:: :  . . ::
NP_071 SPRPARLHRFWEGLPAQVRVVQAAYARHRDGRILLFSGPQFWVFQDRQLEGG-ARPLTEL
     350       360       370       380       390       400         

        410       420       430       440       450       460      
pF1KB5 GRGLPTDKIDAALFWMPNGKTYFFRGNKYYRFNEELRAVDSEYPKNIKVWEGIPESPRGS
       :   : ...::.. :  :::::. :: .:.:..:     :  ::.....::: : ::   
NP_071 GLP-PGEEVDAVFSWPQNGKTYLVRGRQYWRYDEAAARPDPGYPRDLSLWEGAPPSPDDV
      410        420       430       440       450       460       

        470       480       490       500         510              
pF1KB5 FMGSDEVFTYFYKGNKYWKFNNQKLKVEPGYPKSALRDWMGCP--SGG----RPDEGTE-
        . :.   :::.:: .::.: ....:.::  :.    .:. ::  :.:    :: ..:  
NP_071 TV-SNAGDTYFFKGAHYWRFPKNSIKTEPDAPQPMGPNWLDCPAPSSGPRAPRPPKATPV
        470       480       490       500       510       520      

     520       530       540       550       560       570         
pF1KB5 EETEVIIIEVDEEGGGAVSAAAVVLPVLLLLLVLAVGLAVFFFRRHGTPRRLLYCQRSLL
        ::     :... .:   .      :. :::: : ::                       
NP_071 SETCDCQCELNQAAGRWPA------PIPLLLLPLLVGGVASR                  
        530       540             550       560                    

     580  
pF1KB5 DKV

>>NP_005932 (OMIM: 602262) matrix metalloproteinase-16 p  (607 aa)
 initn: 1674 init1: 962 opt: 1158  Z-score: 1223.8  bits: 236.4 E(85289): 2e-61
Smith-Waterman score: 2294; 56.7% identity (80.9% similar) in 570 aa overlap (33-582:41-607)

             10        20        30        40        50        60  
pF1KB5 PAPRPPRCLLLPLLTLGTALASLGSAQSSSFSPEAWLQQYGYLPPGDLRTHTQRSPQSLS
                                     :. :.:::.:::::: : :  . :: ....
NP_005 RLDFVHHSGVFFLQTLLWILCATVCGTEQYFNVEVWLQKYGYLPPTDPRMSVLRSAETMQ
               20        30        40        50        60        70

             70        80        90       100       110       120  
pF1KB5 AAIAAMQKFYGLQVTGKADADTMKAMRRPRCGVPDKFGAEIKANVRRKRYAIQGLKWQHN
       .:.::::.:::...:::.: .:.  :..:::::::.  .  : ..::::::. : ::::.
NP_005 SALAAMQQFYGINMTGKVDRNTIDWMKKPRCGVPDQTRGSSKFHIRRKRYALTGQKWQHK
               80        90       100       110       120       130

            130       140       150       160       170       180  
pF1KB5 EITFCIQNYTPKVGEYATYEAIRKAFRVWESATPLRFREVPYAYIREGHEKQADIMIFFA
       .::. :.: :::::.  : .:::.:: ::...::: :.::::. ...: ....:: :.::
NP_005 HITYSIKNVTPKVGDPETRKAIRRAFDVWQNVTPLTFEEVPYSELENG-KRDVDITIIFA
              140       150       160       170        180         

            190       200       210       220       230       240  
pF1KB5 EGFHGDSTPFDGEGGFLAHAYFPGPNIGGDTHFDSAEPWTVRNEDLNGNDIFLVAVHELG
        ::::::.:::::::::::::::::.::::::::: ::::. : . .:::.:::::::::
NP_005 SGFHGDSSPFDGEGGFLAHAYFPGPGIGGDTHFDSDEPWTLGNPNHDGNDLFLVAVHELG
     190       200       210       220       230       240         

            250       260       270       280       290            
pF1KB5 HALGLEHSSDPSAIMAPFYQWMDTENFVLPDDDRRGIQQLYGGESGFPT-----------
       ::::::::.::.::::::::.:.:.:: ::.:: .:::..::  . .:            
NP_005 HALGLEHSNDPTAIMAPFYQYMETDNFKLPNDDLQGIQKIYGPPDKIPPPTRPLPTVPPH
     250       260       270       280       290       300         

               300       310           320       330       340     
pF1KB5 -KMPP-QPRTTSRPSVPDKPKN-PTYG---PNICDGNFDTVAMLRGEMFVFKERWFWRVR
        ..:: .:: ..::. :  : . :.:    ::::::::.:.:.:: ::::::..::::::
NP_005 RSIPPADPRKNDRPKPPRPPTGRPSYPGAKPNICDGNFNTLAILRREMFVFKDQWFWRVR
     310       320       330       340       350       360         

         350       360       370       380       390       400     
pF1KB5 NNQVMDGYPMPIGQFWRGLPASINTAYERKDGKFVFFKGDKHWVFDEASLEPGYPKHIKE
       ::.::::::: :  :::::: ::...:: .::.::::::.:.::: ...:.::::. .  
NP_005 NNRVMDGYPMQITYFWRGLPPSIDAVYENSDGNFVFFKGNKYWVFKDTTLQPGYPHDLIT
     370       380       390       400       410       420         

         410       420       430       440       450       460     
pF1KB5 LGRGLPTDKIDAALFWMPNGKTYFFRGNKYYRFNEELRAVDSEYPKNIKVWEGIPESPRG
       :: :.:   ::.:..:   ::::::.:..:.:..::....:  ::: : ::.::::::.:
NP_005 LGSGIPPHGIDSAIWWEDVGKTYFFKGDRYWRYSEEMKTMDPGYPKPITVWKGIPESPQG
     430       440       450       460       470       480         

         470       480       490       500         510       520   
pF1KB5 SFMGSDEVFTYFYKGNKYWKFNNQKLKVEPGYPKSALRDWMGC--PSGGRPDEGTEEETE
       .:. ... :::::::..::::::: ::::::::.: :.:.:::  :.  :  ::     .
NP_005 AFVHKENGFTYFYKGKEYWKFNNQILKVEPGYPRSILKDFMGCDGPTD-RVKEGHSPPDD
     490       500       510       520       530        540        

            530       540       550       560       570       580  
pF1KB5 V-IIIEVDEEGGGAVSAAAVVLPVLLLLLVLAVGLAVFFFRRHGTPRRLLYCQRSLLDKV
       : :.:..:. .. .:.: :.:.: .: : .:..  .:: :.:.::::..:::.::. . :
NP_005 VDIVIKLDNTAS-TVKAIAIVIPCILALCLLVLVYTVFQFKRKGTPRHILYCKRSMQEWV
      550       560        570       580       590       600       

>>XP_011526802 (OMIM: 604871) PREDICTED: matrix metallop  (556 aa)
 initn: 1519 init1: 660 opt: 1134  Z-score: 1199.0  bits: 231.7 E(85289): 4.8e-60
Smith-Waterman score: 1639; 46.4% identity (64.7% similar) in 586 aa overlap (18-582:65-556)

                            10        20        30        40       
pF1KB5              MSPAPRPPRCLLLPLLTLGTALASLGSAQSSSFSPEAWLQQYGYLPP
                                     ...:.:    :..  :. . ::..:::: :
XP_011 LLLLLLPALCCLPGAARAAAAAAGAGNRAAVAVAVARADEAEAP-FAGQNWLKSYGYLLP
           40        50        60        70         80        90   

        50        60        70        80        90       100       
pF1KB5 GDLRTHTQRSPQSLSAAIAAMQKFYGLQVTGKADADTMKAMRRPRCGVPDKFGAEIKANV
        : :. . .: ..:..:...::.:::. :::  :  :.. :..:::::::.   ...   
XP_011 YDSRASALHSAKALQSAVSTMQQFYGIPVTGVLDQTTIEWMKKPRCGVPDH--PHLSRRR
           100       110       120       130       140         150 

       110       120       130       140       150       160       
pF1KB5 RRKRYAIQGLKWQHNEITFCIQNYTPKVGEYATYEAIRKAFRVWESATPLRFREVPYAYI
       : ::::. : ::....::. :.::::::::  : .:::.:: ::...::: :.::::  :
XP_011 RNKRYALTGQKWRQKHITYSIHNYTPKVGELDTRKAIRQAFDVWQKVTPLTFEEVPYHEI
             160       170       180       190       200       210 

       170       180       190       200       210       220       
pF1KB5 REGHEKQADIMIFFAEGFHGDSTPFDGEGGFLAHAYFPGPNIGGDTHFDSAEPWTVRNED
       . . .:.:::::::: ::::::.:::::::::::::::::.::::::::: ::::. : .
XP_011 K-SDRKEADIMIFFASGFHGDSSPFDGEGGFLAHAYFPGPGIGGDTHFDSDEPWTLGNAN
              220       230       240       250       260       270

       230       240       250       260       270       280       
pF1KB5 LNGNDIFLVAVHELGHALGLEHSSDPSAIMAPFYQWMDTENFVLPDDDRRGIQQLYG--G
        .:::.:::::::::::::::::::::::::::::.:.:.:: ::.:: .:::..::  .
XP_011 HDGNDLFLVAVHELGHALGLEHSSDPSAIMAPFYQYMETHNFKLPQDDLQGIQKIYGPPA
              280       290       300       310       320       330

         290                        300       310       320        
pF1KB5 ESGFPTKMPP-----------------QPRTTSRPSVPDKPKNPTYGPNICDGNFDTVAM
       :   ::.  :                 :::   :: . :.:..:   ::::::::.:::.
XP_011 EPLEPTRPLPTLPVRRIHSPSERKHERQPRPP-RPPLGDRPSTPGTKPNICDGNFNTVAL
              340       350       360        370       380         

      330       340       350       360       370       380        
pF1KB5 LRGEMFVFKERWFWRVRNNQVMDGYPMPIGQFWRGLPASINTAYERKDGKFVFFKGDKHW
       .::::::::.:::::.:::.:..:::: : :::.:::: :..:::: ::.:::::     
XP_011 FRGEMFVFKDRWFWRLRNNRVQEGYPMQIEQFWKGLPARIDAAYERADGRFVFFKD----
     390       400       410       420       430       440         

      390       400       410       420       430       440        
pF1KB5 VFDEASLEPGYPKHIKELGRGLPTDKIDAALFWMPNGKTYFFRGNKYYRFNEELRAVDSE
                                                                   
XP_011 ------------------------------------------------------------
                                                                   

      450       460       470       480       490       500        
pF1KB5 YPKNIKVWEGIPESPRGSFMGSDEVFTYFYKGNKYWKFNNQKLKVEPGYPKSALRDWMGC
                                .::::::  ::::.::::.::::::.. :::::::
XP_011 -------------------------YTYFYKGRDYWKFDNQKLSVEPGYPRNILRDWMGC
                                  450       460       470       480

      510         520       530       540       550       560      
pF1KB5 PSGG--RPDEGTEEETEVIIIEVDEEGGGAVSAAAVVLPVLLLLLVLAVGLAVFFFRRHG
        .    :  :    . .: :. . ..  :.:.:.:::.: .: : .:..  ..: :. . 
XP_011 NQKEVERRKERRLPQDDVDIMVTINDVPGSVNAVAVVIPCILSLCILVLVYTIFQFKNKT
              490       500       510       520       530       540

        570       580  
pF1KB5 TPRRLLYCQRSLLDKV
        :. . : .: . . :
XP_011 GPQPVTYYKRPVQEWV
              550      

>>NP_057239 (OMIM: 602285) matrix metalloproteinase-17 p  (603 aa)
 initn: 1061 init1: 219 opt: 1134  Z-score: 1198.5  bits: 231.8 E(85289): 5.1e-60
Smith-Waterman score: 1280; 38.6% identity (64.8% similar) in 546 aa overlap (3-518:9-531)

                         10        20        30                40  
pF1KB5       MSPAPRPP----RCLLLPLLTLGTALASLGSAQSSSFSPEA--------WLQQY
               :.: ::      : :::: :  ::.. :.  . . .:.:        ::...
NP_057 MRRRAARGPGPPPPGPGLSRLPLPLLLL-LALGTRGGCAAPAPAPRAEDLSLGVEWLSRF
               10        20         30        40        50         

             50        60        70        80        90       100  
pF1KB5 GYLPPGDLRTHTQRSPQSLSAAIAAMQKFYGLQVTGKADADTMKAMRRPRCGVPDKFGAE
       :::::.:  :   .. . :: ::.:::.: ::..::  :  :.  :. :::..::     
NP_057 GYLPPADPTTGQLQTQEELSKAITAMQQFGGLEATGILDEATLALMKTPRCSLPD---LP
      60        70        80        90       100       110         

            110       120       130          140       150         
pF1KB5 IKANVRRKRYAIQGLKWQHNEITFCIQNYTPK---VGEYATYEAIRKAFRVWESATPLRF
       . ...::.: :    ::.. .... .... :.   .:. ..   .  :..:: . .:: :
NP_057 VLTQARRRRQAPAPTKWNKRNLSWRVRTF-PRDSPLGHDTVRALMYYALKVWSDIAPLNF
        120       130       140        150       160       170     

     160       170       180       190       200        210        
pF1KB5 REVPYAYIREGHEKQADIMIFFAEGFHGDSTPFDGEGGFLAHAYFPGPN-IGGDTHFDSA
       .::  .         :::.: :... :.:. :::: :: .:::.::: .  .::::::. 
NP_057 HEVAGS--------AADIQIDFSKADHNDGYPFDGPGGTVAHAFFPGHHHTAGDTHFDDD
         180               190       200       210       220       

      220       230       240       250       260         270      
pF1KB5 EPWTVRNEDLNGNDIFLVAVHELGHALGLEHSSDPSAIMAPFYQWM--DTENFVLPDDDR
       : :: :. : .: :.: :::::.:::.:: : .   .:: :.::    :   . :: .:.
NP_057 EAWTFRSSDAHGMDLFAVAVHEFGHAIGLSHVAAAHSIMRPYYQGPVGDPLRYGLPYEDK
       230       240       250       260       270       280       

        280        290       300       310             320         
pF1KB5 RGIQQLYG-GESGFPTKMPPQPRTTSRPSVPDKPKNPTYGP------NICDGNFDTVAML
         . ::::  ::  :: .: .:     : .:. : : . .:      . :. .::.::..
NP_057 VRVWQLYGVRESVSPTAQPEEP-----PLLPEPPDNRSSAPPRKDVPHRCSTHFDAVAQI
       290       300            310       320       330       340  

     330       340        350       360          370        380    
pF1KB5 RGEMFVFKERWFWRV-RNNQVMDGYPMPIGQFWRGLPA---SINTAYER-KDGKFVFFKG
       ::: : :: ..:::. :. ....  :  . .::::::    :....::: .: :.:::::
NP_057 RGEAFFFKGKYFWRLTRDRHLVSLQPAQMHRFWRGLPLHLDSVDAVYERTSDHKIVFFKG
            350       360       370       380       390       400  

          390       400       410       420       430       440    
pF1KB5 DKHWVFDEASLEPGYPKHIKELGRGLPTDKIDAALFWMPNGKTYFFRGNKYYRFNEELRA
       :..::: . ..: :::. .....  ::   ::::. :  : .::::. . :.:.... : 
NP_057 DRYWVFKDNNVEEGYPRPVSDFS--LPPGGIDAAFSWAHNDRTYFFKDQLYWRYDDHTRH
            410       420         430       440       450       460

          450       460       470       480       490       500    
pF1KB5 VDSEYPKNIKVWEGIPESPRGSFMGSDEVFTYFYKGNKYWKFNNQKLKVEPGYPKSALRD
       .:  :: .  .:.:.: .   ..  :: . .::..:..:::  . .:.: ::::.:. ::
NP_057 MDPGYPAQSPLWRGVPSTLDDAMRWSDGA-SYFFRGQEYWKVLDGELEVAPGYPQSTARD
              470       480        490       500       510         

          510       520       530       540       550       560    
pF1KB5 WMGCPSGGRPDEGTEEETEVIIIEVDEEGGGAVSAAAVVLPVLLLLLVLAVGLAVFFFRR
       :. :  :    .:.                                              
NP_057 WLVC--GDSQADGSVAAGVDAAEGPRAPPGQHDQSRSEDGYEVCSCTSGASSPPGAPGPL
     520         530       540       550       560       570       

>>XP_016883086 (OMIM: 604871) PREDICTED: matrix metallop  (591 aa)
 initn: 1830 init1: 1043 opt: 1130  Z-score: 1194.4  bits: 231.0 E(85289): 8.7e-60
Smith-Waterman score: 1869; 49.9% identity (72.0% similar) in 567 aa overlap (18-582:65-591)

                            10        20        30        40       
pF1KB5              MSPAPRPPRCLLLPLLTLGTALASLGSAQSSSFSPEAWLQQYGYLPP
                                     ...:.:    :..  :. . ::..:::: :
XP_016 LLLLLLPALCCLPGAARAAAAAAGAGNRAAVAVAVARADEAEAP-FAGQNWLKSYGYLLP
           40        50        60        70         80        90   

        50        60        70        80        90       100       
pF1KB5 GDLRTHTQRSPQSLSAAIAAMQKFYGLQVTGKADADTMKAMRRPRCGVPDKFGAEIKANV
        : :. . .: ..:..:...::.:::. :::  :  :.. :..:::::::.   ...   
XP_016 YDSRASALHSAKALQSAVSTMQQFYGIPVTGVLDQTTIEWMKKPRCGVPDH--PHLSRRR
           100       110       120       130       140         150 

       110       120       130       140       150       160       
pF1KB5 RRKRYAIQGLKWQHNEITFCIQNYTPKVGEYATYEAIRKAFRVWESATPLRFREVPYAYI
       : ::::. : ::....::. :.::::::::  : .:::.:: ::...::: :.::::  :
XP_016 RNKRYALTGQKWRQKHITYSIHNYTPKVGELDTRKAIRQAFDVWQKVTPLTFEEVPYHEI
             160       170       180       190       200       210 

       170       180       190       200       210       220       
pF1KB5 REGHEKQADIMIFFAEGFHGDSTPFDGEGGFLAHAYFPGPNIGGDTHFDSAEPWTVRNED
       . . .:.:::::::: ::::::.:::::::::::::::::.::::::::: ::::     
XP_016 K-SDRKEADIMIFFASGFHGDSSPFDGEGGFLAHAYFPGPGIGGDTHFDSDEPWT-----
              220       230       240       250       260          

       230       240       250       260       270       280       
pF1KB5 LNGNDIFLVAVHELGHALGLEHSSDPSAIMAPFYQWMDTENFVLPDDDRRGIQQLYGGES
                    ::.:   .:.. :.  . :           ::    : :.      :
XP_016 -------------LGNA---NHDGPPAEPLEPTRP--------LPTLPVRRIH------S
                         270       280               290           

       290       300       310       320       330       340       
pF1KB5 GFPTKMPPQPRTTSRPSVPDKPKNPTYGPNICDGNFDTVAMLRGEMFVFKERWFWRVRNN
           :   :::   :: . :.:..:   ::::::::.:::..::::::::.:::::.:::
XP_016 PSERKHERQPRPP-RPPLGDRPSTPGTKPNICDGNFNTVALFRGEMFVFKDRWFWRLRNN
         300        310       320       330       340       350    

       350       360       370       380       390       400       
pF1KB5 QVMDGYPMPIGQFWRGLPASINTAYERKDGKFVFFKGDKHWVFDEASLEPGYPKHIKELG
       .:..:::: : :::.:::: :..:::: ::.::::::::.::: :...:::::. . :::
XP_016 RVQEGYPMQIEQFWKGLPARIDAAYERADGRFVFFKGDKYWVFKEVTVEPGYPHSLGELG
          360       370       380       390       400       410    

       410       420       430       440       450       460       
pF1KB5 RGLPTDKIDAALFWMPNGKTYFFRGNKYYRFNEELRAVDSEYPKNIKVWEGIPESPRGSF
         :: . ::.:: : : ::::::.:..:.:..:: ::.:  ::: : ::.:::..:.:.:
XP_016 SCLPREGIDTALRWEPVGKTYFFKGERYWRYSEERRATDPGYPKPITVWKGIPQAPQGAF
          420       430       440       450       460       470    

       470       480       490       500       510         520     
pF1KB5 MGSDEVFTYFYKGNKYWKFNNQKLKVEPGYPKSALRDWMGCPSGG--RPDEGTEEETEVI
       ....  .::::::  ::::.::::.::::::.. ::::::: .    :  :    . .: 
XP_016 ISKEGYYTYFYKGRDYWKFDNQKLSVEPGYPRNILRDWMGCNQKEVERRKERRLPQDDVD
          480       490       500       510       520       530    

         530       540       550       560       570       580  
pF1KB5 IIEVDEEGGGAVSAAAVVLPVLLLLLVLAVGLAVFFFRRHGTPRRLLYCQRSLLDKV
       :. . ..  :.:.:.:::.: .: : .:..  ..: :. .  :. . : .: . . :
XP_016 IMVTINDVPGSVNAVAVVIPCILSLCILVLVYTIFQFKNKTGPQPVTYYKRPVQEWV
          540       550       560       570       580       590 

>>XP_016883087 (OMIM: 604871) PREDICTED: matrix metallop  (614 aa)
 initn: 1901 init1: 1043 opt: 1130  Z-score: 1194.1  bits: 231.0 E(85289): 9e-60
Smith-Waterman score: 2194; 55.8% identity (77.6% similar) in 568 aa overlap (36-582:51-614)

          10        20        30        40        50        60     
pF1KB5 RPPRCLLLPLLTLGTALASLGSAQSSSFSPEAWLQQYGYLPPGDLRTHTQRSPQSLSAAI
                                     . ::..:::: : : :. . .: ..:..:.
XP_016 QPLPSRMLKSQHFGRRRRRRRRRRLLSRVFQNWLKSYGYLLPYDSRASALHSAKALQSAV
               30        40        50        60        70        80

          70        80        90       100       110       120     
pF1KB5 AAMQKFYGLQVTGKADADTMKAMRRPRCGVPDKFGAEIKANVRRKRYAIQGLKWQHNEIT
       ..::.:::. :::  :  :.. :..:::::::.   ...   : ::::. : ::....::
XP_016 STMQQFYGIPVTGVLDQTTIEWMKKPRCGVPDH--PHLSRRRRNKRYALTGQKWRQKHIT
               90       100       110         120       130        

         130       140       150       160       170       180     
pF1KB5 FCIQNYTPKVGEYATYEAIRKAFRVWESATPLRFREVPYAYIREGHEKQADIMIFFAEGF
       . :.::::::::  : .:::.:: ::...::: :.::::  :. . .:.:::::::: ::
XP_016 YSIHNYTPKVGELDTRKAIRQAFDVWQKVTPLTFEEVPYHEIK-SDRKEADIMIFFASGF
      140       150       160       170       180        190       

         190       200       210       220       230       240     
pF1KB5 HGDSTPFDGEGGFLAHAYFPGPNIGGDTHFDSAEPWTVRNEDLNGNDIFLVAVHELGHAL
       ::::.:::::::::::::::::.::::::::: ::::. : . .:::.::::::::::::
XP_016 HGDSSPFDGEGGFLAHAYFPGPGIGGDTHFDSDEPWTLGNANHDGNDLFLVAVHELGHAL
       200       210       220       230       240       250       

         250       260       270       280         290             
pF1KB5 GLEHSSDPSAIMAPFYQWMDTENFVLPDDDRRGIQQLYG--GESGFPTKMPP--------
       :::::::::::::::::.:.:.:: ::.:: .:::..::  .:   ::.  :        
XP_016 GLEHSSDPSAIMAPFYQYMETHNFKLPQDDLQGIQKIYGPPAEPLEPTRPLPTLPVRRIH
       260       270       280       290       300       310       

                  300       310       320       330       340      
pF1KB5 ---------QPRTTSRPSVPDKPKNPTYGPNICDGNFDTVAMLRGEMFVFKERWFWRVRN
                :::   :: . :.:..:   ::::::::.:::..::::::::.:::::.::
XP_016 SPSERKHERQPRPP-RPPLGDRPSTPGTKPNICDGNFNTVALFRGEMFVFKDRWFWRLRN
       320       330        340       350       360       370      

        350       360       370       380       390       400      
pF1KB5 NQVMDGYPMPIGQFWRGLPASINTAYERKDGKFVFFKGDKHWVFDEASLEPGYPKHIKEL
       :.:..:::: : :::.:::: :..:::: ::.::::::::.::: :...:::::. . ::
XP_016 NRVQEGYPMQIEQFWKGLPARIDAAYERADGRFVFFKGDKYWVFKEVTVEPGYPHSLGEL
        380       390       400       410       420       430      

        410       420       430       440       450       460      
pF1KB5 GRGLPTDKIDAALFWMPNGKTYFFRGNKYYRFNEELRAVDSEYPKNIKVWEGIPESPRGS
       :  :: . ::.:: : : ::::::.:..:.:..:: ::.:  ::: : ::.:::..:.:.
XP_016 GSCLPREGIDTALRWEPVGKTYFFKGERYWRYSEERRATDPGYPKPITVWKGIPQAPQGA
        440       450       460       470       480       490      

        470       480       490       500       510         520    
pF1KB5 FMGSDEVFTYFYKGNKYWKFNNQKLKVEPGYPKSALRDWMGCPSGG--RPDEGTEEETEV
       :....  .::::::  ::::.::::.::::::.. ::::::: .    :  :    . .:
XP_016 FISKEGYYTYFYKGRDYWKFDNQKLSVEPGYPRNILRDWMGCNQKEVERRKERRLPQDDV
        500       510       520       530       540       550      

          530       540       550       560       570       580  
pF1KB5 IIIEVDEEGGGAVSAAAVVLPVLLLLLVLAVGLAVFFFRRHGTPRRLLYCQRSLLDKV
        :. . ..  :.:.:.:::.: .: : .:..  ..: :. .  :. . : .: . . :
XP_016 DIMVTINDVPGSVNAVAVVIPCILSLCILVLVYTIFQFKNKTGPQPVTYYKRPVQEWV
        560       570       580       590       600       610    

>>NP_006681 (OMIM: 604871) matrix metalloproteinase-24 p  (645 aa)
 initn: 1908 init1: 1043 opt: 1130  Z-score: 1193.8  bits: 231.0 E(85289): 9.3e-60
Smith-Waterman score: 2203; 54.8% identity (77.1% similar) in 586 aa overlap (18-582:65-645)

                            10        20        30        40       
pF1KB5              MSPAPRPPRCLLLPLLTLGTALASLGSAQSSSFSPEAWLQQYGYLPP
                                     ...:.:    :..  :. . ::..:::: :
NP_006 LLLLLLPALCCLPGAARAAAAAAGAGNRAAVAVAVARADEAEAP-FAGQNWLKSYGYLLP
           40        50        60        70         80        90   

        50        60        70        80        90       100       
pF1KB5 GDLRTHTQRSPQSLSAAIAAMQKFYGLQVTGKADADTMKAMRRPRCGVPDKFGAEIKANV
        : :. . .: ..:..:...::.:::. :::  :  :.. :..:::::::.   ...   
NP_006 YDSRASALHSAKALQSAVSTMQQFYGIPVTGVLDQTTIEWMKKPRCGVPDH--PHLSRRR
           100       110       120       130       140         150 

       110       120       130       140       150       160       
pF1KB5 RRKRYAIQGLKWQHNEITFCIQNYTPKVGEYATYEAIRKAFRVWESATPLRFREVPYAYI
       : ::::. : ::....::. :.::::::::  : .:::.:: ::...::: :.::::  :
NP_006 RNKRYALTGQKWRQKHITYSIHNYTPKVGELDTRKAIRQAFDVWQKVTPLTFEEVPYHEI
             160       170       180       190       200       210 

       170       180       190       200       210       220       
pF1KB5 REGHEKQADIMIFFAEGFHGDSTPFDGEGGFLAHAYFPGPNIGGDTHFDSAEPWTVRNED
       . . .:.:::::::: ::::::.:::::::::::::::::.::::::::: ::::. : .
NP_006 K-SDRKEADIMIFFASGFHGDSSPFDGEGGFLAHAYFPGPGIGGDTHFDSDEPWTLGNAN
              220       230       240       250       260       270

       230       240       250       260       270       280       
pF1KB5 LNGNDIFLVAVHELGHALGLEHSSDPSAIMAPFYQWMDTENFVLPDDDRRGIQQLYG--G
        .:::.:::::::::::::::::::::::::::::.:.:.:: ::.:: .:::..::  .
NP_006 HDGNDLFLVAVHELGHALGLEHSSDPSAIMAPFYQYMETHNFKLPQDDLQGIQKIYGPPA
              280       290       300       310       320       330

         290                        300       310       320        
pF1KB5 ESGFPTKMPP-----------------QPRTTSRPSVPDKPKNPTYGPNICDGNFDTVAM
       :   ::.  :                 :::   :: . :.:..:   ::::::::.:::.
NP_006 EPLEPTRPLPTLPVRRIHSPSERKHERQPRPP-RPPLGDRPSTPGTKPNICDGNFNTVAL
              340       350       360        370       380         

      330       340       350       360       370       380        
pF1KB5 LRGEMFVFKERWFWRVRNNQVMDGYPMPIGQFWRGLPASINTAYERKDGKFVFFKGDKHW
       .::::::::.:::::.:::.:..:::: : :::.:::: :..:::: ::.::::::::.:
NP_006 FRGEMFVFKDRWFWRLRNNRVQEGYPMQIEQFWKGLPARIDAAYERADGRFVFFKGDKYW
     390       400       410       420       430       440         

      390       400       410       420       430       440        
pF1KB5 VFDEASLEPGYPKHIKELGRGLPTDKIDAALFWMPNGKTYFFRGNKYYRFNEELRAVDSE
       :: :...:::::. . :::  :: . ::.:: : : ::::::.:..:.:..:: ::.:  
NP_006 VFKEVTVEPGYPHSLGELGSCLPREGIDTALRWEPVGKTYFFKGERYWRYSEERRATDPG
     450       460       470       480       490       500         

      450       460       470       480       490       500        
pF1KB5 YPKNIKVWEGIPESPRGSFMGSDEVFTYFYKGNKYWKFNNQKLKVEPGYPKSALRDWMGC
       ::: : ::.:::..:.:.:....  .::::::  ::::.::::.::::::.. :::::::
NP_006 YPKPITVWKGIPQAPQGAFISKEGYYTYFYKGRDYWKFDNQKLSVEPGYPRNILRDWMGC
     510       520       530       540       550       560         

      510         520       530       540       550       560      
pF1KB5 PSGG--RPDEGTEEETEVIIIEVDEEGGGAVSAAAVVLPVLLLLLVLAVGLAVFFFRRHG
        .    :  :    . .: :. . ..  :.:.:.:::.: .: : .:..  ..: :. . 
NP_006 NQKEVERRKERRLPQDDVDIMVTINDVPGSVNAVAVVIPCILSLCILVLVYTIFQFKNKT
     570       580       590       600       610       620         

        570       580  
pF1KB5 TPRRLLYCQRSLLDKV
        :. . : .: . . :
NP_006 GPQPVTYYKRPVQEWV
     630       640     

>>XP_011520904 (OMIM: 608482) PREDICTED: matrix metallop  (528 aa)
 initn: 1033 init1: 245 opt: 1106  Z-score: 1169.8  bits: 226.3 E(85289): 2e-58
Smith-Waterman score: 1187; 40.2% identity (65.8% similar) in 497 aa overlap (81-556:44-523)

               60        70        80        90       100       110
pF1KB5 RTHTQRSPQSLSAAIAAMQKFYGLQVTGKADADTMKAMRRPRCGVPDKFGAEIKANVRRK
                                     :  :. .::.:::..:: .:.   .  ::.
XP_011 KTPRHAEACVPGAKGALKSSGERPQPRALKDPGTVATMRKPRCSLPDVLGVAGLVR-RRR
            20        30        40        50        60         70  

              120       130       140           150       160      
pF1KB5 RYAIQGLKWQHNEITFCIQNYTPKVGEYATYEAIR----KAFRVWESATPLRFREVPYAY
       :::..:  :..  .:. .... :. ..  . :..:     :. .:   . : :.::    
XP_011 RYALSGSVWKKRTLTWRVRSF-PQSSQL-SQETVRVLMSYALMAWGMESGLTFHEVDSP-
             80        90         100       110       120          

        170       180       190       200        210       220     
pF1KB5 IREGHEKQADIMIFFAEGFHGDSTPFDGEGGFLAHAYFPGPN-IGGDTHFDSAEPWTVRN
         .:.:   ::.: ::..:: :: :::: :: ::::.::: . :.::::::. : ::  .
XP_011 --QGQE--PDILIDFARAFHQDSYPFDGLGGTLAHAFFPGEHPISGDTHFDDEETWTFGS
       130         140       150       160       170       180     

         230       240       250       260         270       280   
pF1KB5 EDLNGNDIFLVAVHELGHALGLEHSSDPSAIMAPFYQWM--DTENFVLPDDDRRGIQQLY
       .: .:.:.: :::::.:::::: ::: :..:: ::::    : ... : .::: :.::::
XP_011 KDGEGTDLFAVAVHEFGHALGLGHSSAPNSIMRPFYQGPVGDPDKYRLSQDDRDGLQQLY
         190       200       210       220       230       240     

           290       300        310        320       330       340 
pF1KB5 GGESGFPTKMPPQPRTTSRPSVPDKP-KNPTYG-PNICDGNFDTVAMLRGEMFVFKERWF
       :     :   : .   .  :. : .: ..:..  :. :.::::..: .::: : ::  ::
XP_011 GKAPQTPYDKPTRKPLAPPPQPPASPTHSPSFPIPDRCEGNFDAIANIRGETFFFKGPWF
         250       260       270       280       290       300     

              350       360          370        380       390      
pF1KB5 WRVR-NNQVMDGYPMPIGQFWRGLPASI---NTAYER-KDGKFVFFKGDKHWVFDEASLE
       ::.. ..:...  :  . .::.::::..   ..:: : .::....:.: . :::.. .::
XP_011 WRLQPSGQLVSPRPARLHRFWEGLPAQVRVVQAAYARHRDGRILLFSGPQFWVFQDRQLE
         310       320       330       340       350       360     

        400       410       420       430       440       450      
pF1KB5 PGYPKHIKELGRGLPTDKIDAALFWMPNGKTYFFRGNKYYRFNEELRAVDSEYPKNIKVW
        :  . . :::   : ...::.. :  :::::. :: .:.:..:     :  ::.....:
XP_011 GG-ARPLTELGLP-PGEEVDAVFSWPQNGKTYLVRGRQYWRYDEAAARPDPGYPRDLSLW
          370        380       390       400       410       420   

        460       470       480       490       500         510    
pF1KB5 EGIPESPRGSFMGSDEVFTYFYKGNKYWKFNNQKLKVEPGYPKSALRDWMGCP--SGG--
       :: : ::    . :.   :::.:: .::.: ....:.::  :.    .:. ::  :.:  
XP_011 EGAPPSPDDVTV-SNAGDTYFFKGAHYWRFPKNSIKTEPDAPQPMGPNWLDCPAPSSGPR
           430        440       450       460       470       480  

               520       530       540       550       560         
pF1KB5 --RPDEGTE-EETEVIIIEVDEEGGGAVSAAAVVLPVLLLLLVLAVGLAVFFFRRHGTPR
         :: ..:   ::     :... .:   .      :. :::: : ::             
XP_011 APRPPKATPVSETCDCQCELNQAAGRWPA------PIPLLLLPLLVGGVASR        
            490       500       510             520                

     570       580  
pF1KB5 RLLYCQRSLLDKV

>>XP_011520906 (OMIM: 608482) PREDICTED: matrix metallop  (478 aa)
 initn: 1033 init1: 245 opt: 1095  Z-score: 1158.8  bits: 224.1 E(85289): 8.3e-58
Smith-Waterman score: 1176; 40.4% identity (65.9% similar) in 490 aa overlap (88-556:1-473)

        60        70        80        90       100       110       
pF1KB5 PQSLSAAIAAMQKFYGLQVTGKADADTMKAMRRPRCGVPDKFGAEIKANVRRKRYAIQGL
                                     ::.:::..:: .:.   .  ::.:::..: 
XP_011                               MRKPRCSLPDVLGVAGLVR-RRRRYALSGS
                                             10         20         

       120       130       140           150       160       170   
pF1KB5 KWQHNEITFCIQNYTPKVGEYATYEAIR----KAFRVWESATPLRFREVPYAYIREGHEK
        :..  .:. .... :. ..  . :..:     :. .:   . : :.::      .:.: 
XP_011 VWKKRTLTWRVRSF-PQSSQL-SQETVRVLMSYALMAWGMESGLTFHEVDSP---QGQE-
      30        40          50        60        70           80    

           180       190       200        210       220       230  
pF1KB5 QADIMIFFAEGFHGDSTPFDGEGGFLAHAYFPGPN-IGGDTHFDSAEPWTVRNEDLNGND
         ::.: ::..:: :: :::: :: ::::.::: . :.::::::. : ::  ..: .:.:
XP_011 -PDILIDFARAFHQDSYPFDGLGGTLAHAFFPGEHPISGDTHFDDEETWTFGSKDGEGTD
             90       100       110       120       130       140  

            240       250       260         270       280       290
pF1KB5 IFLVAVHELGHALGLEHSSDPSAIMAPFYQWM--DTENFVLPDDDRRGIQQLYGGESGFP
       .: :::::.:::::: ::: :..:: ::::    : ... : .::: :.:::::     :
XP_011 LFAVAVHEFGHALGLGHSSAPNSIMRPFYQGPVGDPDKYRLSQDDRDGLQQLYGKAPQTP
            150       160       170       180       190       200  

              300        310        320       330       340        
pF1KB5 TKMPPQPRTTSRPSVPDKP-KNPTYG-PNICDGNFDTVAMLRGEMFVFKERWFWRVR-NN
          : .   .  :. : .: ..:..  :. :.::::..: .::: : ::  ::::.. ..
XP_011 YDKPTRKPLAPPPQPPASPTHSPSFPIPDRCEGNFDAIANIRGETFFFKGPWFWRLQPSG
            210       220       230       240       250       260  

       350       360          370        380       390       400   
pF1KB5 QVMDGYPMPIGQFWRGLPASI---NTAYER-KDGKFVFFKGDKHWVFDEASLEPGYPKHI
       :...  :  . .::.::::..   ..:: : .::....:.: . :::.. .:: :  . .
XP_011 QLVSPRPARLHRFWEGLPAQVRVVQAAYARHRDGRILLFSGPQFWVFQDRQLEGG-ARPL
            270       280       290       300       310        320 

           410       420       430       440       450       460   
pF1KB5 KELGRGLPTDKIDAALFWMPNGKTYFFRGNKYYRFNEELRAVDSEYPKNIKVWEGIPESP
        :::   : ...::.. :  :::::. :: .:.:..:     :  ::.....::: : ::
XP_011 TELGLP-PGEEVDAVFSWPQNGKTYLVRGRQYWRYDEAAARPDPGYPRDLSLWEGAPPSP
              330       340       350       360       370       380

           470       480       490       500         510           
pF1KB5 RGSFMGSDEVFTYFYKGNKYWKFNNQKLKVEPGYPKSALRDWMGCP--SGG----RPDEG
           . :.   :::.:: .::.: ....:.::  :.    .:. ::  :.:    :: ..
XP_011 DDVTV-SNAGDTYFFKGAHYWRFPKNSIKTEPDAPQPMGPNWLDCPAPSSGPRAPRPPKA
               390       400       410       420       430         

        520       530       540       550       560       570      
pF1KB5 TE-EETEVIIIEVDEEGGGAVSAAAVVLPVLLLLLVLAVGLAVFFFRRHGTPRRLLYCQR
       :   ::     :... .:   .      :. :::: : ::                    
XP_011 TPVSETCDCQCELNQAAGRWPA------PIPLLLLPLLVGGVASR               
     440       450       460             470                       

        580  
pF1KB5 SLLDKV




582 residues in 1 query   sequences
60827320 residues in 85289 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Thu Nov  3 15:59:58 2016 done: Thu Nov  3 16:00:00 2016
 Total Scan time: 10.700 Total Display time:  0.100

Function used was FASTA [36.3.4 Apr, 2011]
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