Result of FASTA (omim) for pF1KB4303
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KB4303, 635 aa
  1>>>pF1KB4303 635 - 635 aa - 635 aa
Library: /omim/omim.rfq.tfa
  60827320 residues in 85289 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 9.1920+/-0.000463; mu= 3.4180+/- 0.028
 mean_var=528.9077+/-116.277, 0's: 0 Z-trim(121.4): 1403  B-trim: 0 in 0/56
 Lambda= 0.055768
 statistics sampled from 36019 (37903) to 36019 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.765), E-opt: 0.2 (0.444), width:  16
 Scan time: 12.830

The best scores are:                                      opt bits E(85289)
NP_001075031 (OMIM: 160900,605377) myotonin-protei ( 625) 3951 333.4 1.4e-90
NP_001075032 (OMIM: 160900,605377) myotonin-protei ( 639) 3754 317.6 8.5e-86
NP_001275694 (OMIM: 160900,605377) myotonin-protei ( 541) 3707 313.7 1.1e-84
NP_001075029 (OMIM: 160900,605377) myotonin-protei ( 624) 3308 281.7 5.3e-75
NP_001275693 (OMIM: 160900,605377) myotonin-protei ( 655) 3291 280.4 1.4e-74
NP_004400 (OMIM: 160900,605377) myotonin-protein k ( 629) 3288 280.1 1.6e-74
NP_001275695 (OMIM: 160900,605377) myotonin-protei ( 530) 3189 272.0 3.7e-72
XP_016858071 (OMIM: 603412) PREDICTED: serine/thre (1589) 1580 143.3 6.1e-33
NP_055641 (OMIM: 603412) serine/threonine-protein  (1638) 1580 143.4 6.2e-33
NP_003598 (OMIM: 603412) serine/threonine-protein  (1719) 1580 143.4 6.3e-33
XP_005273381 (OMIM: 603412) PREDICTED: serine/thre (1732) 1580 143.4 6.4e-33
XP_005273379 (OMIM: 603412) PREDICTED: serine/thre (1754) 1580 143.4 6.4e-33
XP_011542611 (OMIM: 603412) PREDICTED: serine/thre (1764) 1580 143.4 6.4e-33
XP_016858067 (OMIM: 603412) PREDICTED: serine/thre (1767) 1580 143.4 6.4e-33
XP_005273378 (OMIM: 603412) PREDICTED: serine/thre (1781) 1580 143.4 6.5e-33
XP_011542610 (OMIM: 603412) PREDICTED: serine/thre (1783) 1580 143.4 6.5e-33
XP_005273377 (OMIM: 603412) PREDICTED: serine/thre (1794) 1580 143.4 6.5e-33
XP_006711898 (OMIM: 603412) PREDICTED: serine/thre (1797) 1580 143.4 6.5e-33
XP_011542609 (OMIM: 603412) PREDICTED: serine/thre (1810) 1580 143.4 6.5e-33
XP_006711897 (OMIM: 603412) PREDICTED: serine/thre (1816) 1580 143.4 6.5e-33
XP_005273375 (OMIM: 603412) PREDICTED: serine/thre (1829) 1580 143.4 6.5e-33
XP_005273374 (OMIM: 603412) PREDICTED: serine/thre (1832) 1580 143.4 6.6e-33
XP_011542608 (OMIM: 603412) PREDICTED: serine/thre (1845) 1580 143.4 6.6e-33
XP_016873487 (OMIM: 613991) PREDICTED: serine/thre (1081) 1552 140.8 2.4e-32
XP_011543463 (OMIM: 613991) PREDICTED: serine/thre (1135) 1552 140.9 2.4e-32
XP_016873486 (OMIM: 613991) PREDICTED: serine/thre (1139) 1552 140.9 2.4e-32
XP_011543461 (OMIM: 613991) PREDICTED: serine/thre (1481) 1552 141.0 2.8e-32
XP_011543460 (OMIM: 613991) PREDICTED: serine/thre (1495) 1552 141.0 2.8e-32
XP_011543459 (OMIM: 613991) PREDICTED: serine/thre (1530) 1552 141.1 2.8e-32
NP_059995 (OMIM: 613991) serine/threonine-protein  (1551) 1552 141.1 2.9e-32
XP_011543458 (OMIM: 613991) PREDICTED: serine/thre (1562) 1552 141.1 2.9e-32
XP_016873485 (OMIM: 613991) PREDICTED: serine/thre (1568) 1552 141.1 2.9e-32
XP_011543457 (OMIM: 613991) PREDICTED: serine/thre (1569) 1552 141.1 2.9e-32
XP_011535689 (OMIM: 614062) PREDICTED: serine/thre (1460) 1540 140.1 5.4e-32
XP_005268287 (OMIM: 614062) PREDICTED: serine/thre (1490) 1540 140.1 5.5e-32
XP_005268286 (OMIM: 614062) PREDICTED: serine/thre (1685) 1540 140.2 5.8e-32
XP_005268285 (OMIM: 614062) PREDICTED: serine/thre (1702) 1540 140.2 5.9e-32
NP_006026 (OMIM: 614062) serine/threonine-protein  (1711) 1540 140.2 5.9e-32
XP_005268284 (OMIM: 614062) PREDICTED: serine/thre (1728) 1540 140.2 5.9e-32
XP_016858070 (OMIM: 603412) PREDICTED: serine/thre (1712) 1391 128.2 2.4e-28
XP_016858069 (OMIM: 603412) PREDICTED: serine/thre (1741) 1391 128.2 2.4e-28
XP_016858068 (OMIM: 603412) PREDICTED: serine/thre (1741) 1391 128.2 2.4e-28
XP_011543462 (OMIM: 613991) PREDICTED: serine/thre (1471) 1340 124.0 3.8e-27
NP_005397 (OMIM: 601702) rho-associated protein ki (1354) 1206 113.1 6.4e-24
NP_004841 (OMIM: 604002) rho-associated protein ki (1388) 1191 111.9 1.5e-23
XP_016860867 (OMIM: 604002) PREDICTED: rho-associa (1404) 1191 112.0 1.5e-23
XP_005246247 (OMIM: 604002) PREDICTED: rho-associa (1417) 1191 112.0 1.5e-23
NP_001308572 (OMIM: 604002) rho-associated protein (1302) 1172 110.4 4.2e-23
XP_016860868 (OMIM: 604002) PREDICTED: rho-associa (1331) 1172 110.4 4.2e-23
XP_011508719 (OMIM: 604002) PREDICTED: rho-associa (1331) 1172 110.4 4.2e-23


>>NP_001075031 (OMIM: 160900,605377) myotonin-protein ki  (625 aa)
 initn: 3947 init1: 3947 opt: 3951  Z-score: 1747.1  bits: 333.4 E(85289): 1.4e-90
Smith-Waterman score: 3951; 97.5% identity (98.3% similar) in 591 aa overlap (45-635:36-625)

           20        30        40        50        60        70    
pF1KB4 MWGSPWEADSPRVKLRGREKGRQTEGGAFPLVSSALSGDPRFFSPTTPPAEPIVVRLKEV
                                     : .: :. : .. .     :::::::::::
NP_001 RLRRLQQLVLDPGFLGLEPLLDLLLGVHQELGASELAQD-KYVADFLQWAEPIVVRLKEV
          10        20        30        40         50        60    

           80        90       100       110       120       130    
pF1KB4 RLQRDDFEILKVIGRGAFSEVAVVKMKQTGQVYAMKIMNKWDMLKRGEVSCFREERDVLV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RLQRDDFEILKVIGRGAFSEVAVVKMKQTGQVYAMKIMNKWDMLKRGEVSCFREERDVLV
           70        80        90       100       110       120    

          140       150       160       170       180       190    
pF1KB4 NGDRRWITQLHFAFQDENYLYLVMEYYVGGDLLTLLSKFGERIPAEMARFYLAEIVMAID
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NGDRRWITQLHFAFQDENYLYLVMEYYVGGDLLTLLSKFGERIPAEMARFYLAEIVMAID
          130       140       150       160       170       180    

          200       210       220       230       240       250    
pF1KB4 SVHRLGYVHRDIKPDNILLDRCGHIRLADFGSCLKLRADGTVRSLVAVGTPDYLSPEILQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SVHRLGYVHRDIKPDNILLDRCGHIRLADFGSCLKLRADGTVRSLVAVGTPDYLSPEILQ
          190       200       210       220       230       240    

          260       270       280       290       300       310    
pF1KB4 AVGGGPGTGSYGPECDWWALGVFAYEMFYGQTPFYADSTAETYGKIVHYKEHLSLPLVDE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AVGGGPGTGSYGPECDWWALGVFAYEMFYGQTPFYADSTAETYGKIVHYKEHLSLPLVDE
          250       260       270       280       290       300    

          320       330       340       350       360       370    
pF1KB4 GVPEEARDFIQRLLCPPETRLGRGGAGDFRTHPFFFGLDWDGLRDSVPPFTPDFEGATDT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GVPEEARDFIQRLLCPPETRLGRGGAGDFRTHPFFFGLDWDGLRDSVPPFTPDFEGATDT
          310       320       330       340       350       360    

          380       390       400       410       420       430    
pF1KB4 CNFDLVEDGLTAMETLSDIREGAPLGVHLPFVGYSYSCMALRDSEVPGPTPMELEAEQLL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 CNFDLVEDGLTAMETLSDIREGAPLGVHLPFVGYSYSCMALRDSEVPGPTPMELEAEQLL
          370       380       390       400       410       420    

          440       450       460       470       480       490    
pF1KB4 EPHVQAPSLEPSVSPQDETAEVAVPAAVPAAEAEAEVTLRELQEALEEEVLTRQSLSREM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EPHVQAPSLEPSVSPQDETAEVAVPAAVPAAEAEAEVTLRELQEALEEEVLTRQSLSREM
          430       440       450       460       470       480    

          500       510       520       530       540       550    
pF1KB4 EAIRTDNQNFASQLREAEARNRDLEAHVRQLQERMELLQAEGATAVTGVPSPRATDPPSH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EAIRTDNQNFASQLREAEARNRDLEAHVRQLQERMELLQAEGATAVTGVPSPRATDPPSH
          490       500       510       520       530       540    

          560       570       580       590       600       610    
pF1KB4 MAPRPWLWASARWWGQAPCTAATCCSLPGSLGLAYRRRFPCSCSPLFCLVPPPWAALGWW
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MAPRPWLWASARWWGQAPCTAATCCSLPGSLGLAYRRRFPCSCSPLFCLVPPPWAALGWW
          550       560       570       580       590       600    

          620       630     
pF1KB4 PTPANSPQSGAAQEPPALPEP
       :::::::::::::::::::::
NP_001 PTPANSPQSGAAQEPPALPEP
          610       620     

>>NP_001075032 (OMIM: 160900,605377) myotonin-protein ki  (639 aa)
 initn: 3760 init1: 2698 opt: 3754  Z-score: 1661.3  bits: 317.6 E(85289): 8.5e-86
Smith-Waterman score: 3754; 98.4% identity (98.6% similar) in 564 aa overlap (1-559:1-564)

               10        20        30        40        50        60
pF1KB4 MGGHFWPPEPYTVFMWGSPWEADSPRVKLRGREKGRQTEGGAFPLVSSALSGDPRFFSPT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MGGHFWPPEPYTVFMWGSPWEADSPRVKLRGREKGRQTEGGAFPLVSSALSGDPRFFSPT
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB4 TPPAEPIVVRLKEVRLQRDDFEILKVIGRGAFSEVAVVKMKQTGQVYAMKIMNKWDMLKR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TPPAEPIVVRLKEVRLQRDDFEILKVIGRGAFSEVAVVKMKQTGQVYAMKIMNKWDMLKR
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB4 GEVSCFREERDVLVNGDRRWITQLHFAFQDENYLYLVMEYYVGGDLLTLLSKFGERIPAE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GEVSCFREERDVLVNGDRRWITQLHFAFQDENYLYLVMEYYVGGDLLTLLSKFGERIPAE
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB4 MARFYLAEIVMAIDSVHRLGYVHRDIKPDNILLDRCGHIRLADFGSCLKLRADGTVRSLV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MARFYLAEIVMAIDSVHRLGYVHRDIKPDNILLDRCGHIRLADFGSCLKLRADGTVRSLV
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB4 AVGTPDYLSPEILQAVGGGPGTGSYGPECDWWALGVFAYEMFYGQTPFYADSTAETYGKI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AVGTPDYLSPEILQAVGGGPGTGSYGPECDWWALGVFAYEMFYGQTPFYADSTAETYGKI
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KB4 VHYKEHLSLPLVDEGVPEEARDFIQRLLCPPETRLGRGGAGDFRTHPFFFGLDWDGLRDS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VHYKEHLSLPLVDEGVPEEARDFIQRLLCPPETRLGRGGAGDFRTHPFFFGLDWDGLRDS
              310       320       330       340       350       360

              370       380            390       400       410     
pF1KB4 VPPFTPDFEGATDTCNFDLVEDGLTAM-----ETLSDIREGAPLGVHLPFVGYSYSCMAL
       :::::::::::::::::::::::::::     ::::::::::::::::::::::::::::
NP_001 VPPFTPDFEGATDTCNFDLVEDGLTAMVSGGGETLSDIREGAPLGVHLPFVGYSYSCMAL
              370       380       390       400       410       420

         420       430       440       450       460       470     
pF1KB4 RDSEVPGPTPMELEAEQLLEPHVQAPSLEPSVSPQDETAEVAVPAAVPAAEAEAEVTLRE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RDSEVPGPTPMELEAEQLLEPHVQAPSLEPSVSPQDETAEVAVPAAVPAAEAEAEVTLRE
              430       440       450       460       470       480

         480       490       500       510       520       530     
pF1KB4 LQEALEEEVLTRQSLSREMEAIRTDNQNFASQLREAEARNRDLEAHVRQLQERMELLQAE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LQEALEEEVLTRQSLSREMEAIRTDNQNFASQLREAEARNRDLEAHVRQLQERMELLQAE
              490       500       510       520       530       540

         540       550       560       570       580       590     
pF1KB4 GATAVTGVPSPRATDPPSHMAPRPWLWASARWWGQAPCTAATCCSLPGSLGLAYRRRFPC
       :::::::::::::::::::.   :                                    
NP_001 GATAVTGVPSPRATDPPSHLDGPPAVAVGQCPLVGPGPMHRRHLLLPARVPRPGLSEALS
              550       560       570       580       590       600

>>NP_001275694 (OMIM: 160900,605377) myotonin-protein ki  (541 aa)
 initn: 3713 init1: 2008 opt: 3707  Z-score: 1641.6  bits: 313.7 E(85289): 1.1e-84
Smith-Waterman score: 3707; 99.1% identity (99.1% similar) in 541 aa overlap (100-635:1-541)

      70        80        90       100       110       120         
pF1KB4 RLKEVRLQRDDFEILKVIGRGAFSEVAVVKMKQTGQVYAMKIMNKWDMLKRGEVSCFREE
                                     ::::::::::::::::::::::::::::::
NP_001                               MKQTGQVYAMKIMNKWDMLKRGEVSCFREE
                                             10        20        30

     130       140       150       160       170       180         
pF1KB4 RDVLVNGDRRWITQLHFAFQDENYLYLVMEYYVGGDLLTLLSKFGERIPAEMARFYLAEI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RDVLVNGDRRWITQLHFAFQDENYLYLVMEYYVGGDLLTLLSKFGERIPAEMARFYLAEI
               40        50        60        70        80        90

     190       200       210       220       230       240         
pF1KB4 VMAIDSVHRLGYVHRDIKPDNILLDRCGHIRLADFGSCLKLRADGTVRSLVAVGTPDYLS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VMAIDSVHRLGYVHRDIKPDNILLDRCGHIRLADFGSCLKLRADGTVRSLVAVGTPDYLS
              100       110       120       130       140       150

     250       260       270       280       290       300         
pF1KB4 PEILQAVGGGPGTGSYGPECDWWALGVFAYEMFYGQTPFYADSTAETYGKIVHYKEHLSL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PEILQAVGGGPGTGSYGPECDWWALGVFAYEMFYGQTPFYADSTAETYGKIVHYKEHLSL
              160       170       180       190       200       210

     310       320       330       340       350       360         
pF1KB4 PLVDEGVPEEARDFIQRLLCPPETRLGRGGAGDFRTHPFFFGLDWDGLRDSVPPFTPDFE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PLVDEGVPEEARDFIQRLLCPPETRLGRGGAGDFRTHPFFFGLDWDGLRDSVPPFTPDFE
              220       230       240       250       260       270

     370       380            390       400       410       420    
pF1KB4 GATDTCNFDLVEDGLTAM-----ETLSDIREGAPLGVHLPFVGYSYSCMALRDSEVPGPT
       ::::::::::::::::::     :::::::::::::::::::::::::::::::::::::
NP_001 GATDTCNFDLVEDGLTAMVSGGGETLSDIREGAPLGVHLPFVGYSYSCMALRDSEVPGPT
              280       290       300       310       320       330

          430       440       450       460       470       480    
pF1KB4 PMELEAEQLLEPHVQAPSLEPSVSPQDETAEVAVPAAVPAAEAEAEVTLRELQEALEEEV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PMELEAEQLLEPHVQAPSLEPSVSPQDETAEVAVPAAVPAAEAEAEVTLRELQEALEEEV
              340       350       360       370       380       390

          490       500       510       520       530       540    
pF1KB4 LTRQSLSREMEAIRTDNQNFASQLREAEARNRDLEAHVRQLQERMELLQAEGATAVTGVP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LTRQSLSREMEAIRTDNQNFASQLREAEARNRDLEAHVRQLQERMELLQAEGATAVTGVP
              400       410       420       430       440       450

          550       560       570       580       590       600    
pF1KB4 SPRATDPPSHMAPRPWLWASARWWGQAPCTAATCCSLPGSLGLAYRRRFPCSCSPLFCLV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SPRATDPPSHMAPRPWLWASARWWGQAPCTAATCCSLPGSLGLAYRRRFPCSCSPLFCLV
              460       470       480       490       500       510

          610       620       630     
pF1KB4 PPPWAALGWWPTPANSPQSGAAQEPPALPEP
       :::::::::::::::::::::::::::::::
NP_001 PPPWAALGWWPTPANSPQSGAAQEPPALPEP
              520       530       540 

>>NP_001075029 (OMIM: 160900,605377) myotonin-protein ki  (624 aa)
 initn: 3304 init1: 3304 opt: 3308  Z-score: 1467.5  bits: 281.7 E(85289): 5.3e-75
Smith-Waterman score: 3308; 96.3% identity (97.5% similar) in 515 aa overlap (45-559:36-549)

           20        30        40        50        60        70    
pF1KB4 MWGSPWEADSPRVKLRGREKGRQTEGGAFPLVSSALSGDPRFFSPTTPPAEPIVVRLKEV
                                     : .: :. : .. .     :::::::::::
NP_001 RLRRLQQLVLDPGFLGLEPLLDLLLGVHQELGASELAQD-KYVADFLQWAEPIVVRLKEV
          10        20        30        40         50        60    

           80        90       100       110       120       130    
pF1KB4 RLQRDDFEILKVIGRGAFSEVAVVKMKQTGQVYAMKIMNKWDMLKRGEVSCFREERDVLV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RLQRDDFEILKVIGRGAFSEVAVVKMKQTGQVYAMKIMNKWDMLKRGEVSCFREERDVLV
           70        80        90       100       110       120    

          140       150       160       170       180       190    
pF1KB4 NGDRRWITQLHFAFQDENYLYLVMEYYVGGDLLTLLSKFGERIPAEMARFYLAEIVMAID
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NGDRRWITQLHFAFQDENYLYLVMEYYVGGDLLTLLSKFGERIPAEMARFYLAEIVMAID
          130       140       150       160       170       180    

          200       210       220       230       240       250    
pF1KB4 SVHRLGYVHRDIKPDNILLDRCGHIRLADFGSCLKLRADGTVRSLVAVGTPDYLSPEILQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SVHRLGYVHRDIKPDNILLDRCGHIRLADFGSCLKLRADGTVRSLVAVGTPDYLSPEILQ
          190       200       210       220       230       240    

          260       270       280       290       300       310    
pF1KB4 AVGGGPGTGSYGPECDWWALGVFAYEMFYGQTPFYADSTAETYGKIVHYKEHLSLPLVDE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AVGGGPGTGSYGPECDWWALGVFAYEMFYGQTPFYADSTAETYGKIVHYKEHLSLPLVDE
          250       260       270       280       290       300    

          320       330       340       350       360       370    
pF1KB4 GVPEEARDFIQRLLCPPETRLGRGGAGDFRTHPFFFGLDWDGLRDSVPPFTPDFEGATDT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GVPEEARDFIQRLLCPPETRLGRGGAGDFRTHPFFFGLDWDGLRDSVPPFTPDFEGATDT
          310       320       330       340       350       360    

          380       390       400       410       420       430    
pF1KB4 CNFDLVEDGLTAMETLSDIREGAPLGVHLPFVGYSYSCMALRDSEVPGPTPMELEAEQLL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 CNFDLVEDGLTAMETLSDIREGAPLGVHLPFVGYSYSCMALRDSEVPGPTPMELEAEQLL
          370       380       390       400       410       420    

          440       450       460       470       480       490    
pF1KB4 EPHVQAPSLEPSVSPQDETAEVAVPAAVPAAEAEAEVTLRELQEALEEEVLTRQSLSREM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EPHVQAPSLEPSVSPQDETAEVAVPAAVPAAEAEAEVTLRELQEALEEEVLTRQSLSREM
          430       440       450       460       470       480    

          500       510       520       530       540       550    
pF1KB4 EAIRTDNQNFASQLREAEARNRDLEAHVRQLQERMELLQAEGATAVTGVPSPRATDPPSH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EAIRTDNQNFASQLREAEARNRDLEAHVRQLQERMELLQAEGATAVTGVPSPRATDPPSH
          490       500       510       520       530       540    

          560       570       580       590       600       610    
pF1KB4 MAPRPWLWASARWWGQAPCTAATCCSLPGSLGLAYRRRFPCSCSPLFCLVPPPWAALGWW
       .   :                                                       
NP_001 LDGPPAVAVGQCPLVGPGPMHRRHLLLPARVPRPGLSEALSLLLFAVVLSRAAALGCIGL
          550       560       570       580       590       600    

>>NP_001275693 (OMIM: 160900,605377) myotonin-protein ki  (655 aa)
 initn: 3290 init1: 2228 opt: 3291  Z-score: 1459.9  bits: 280.4 E(85289): 1.4e-74
Smith-Waterman score: 3291; 93.3% identity (95.0% similar) in 535 aa overlap (31-559:50-580)

               10        20        30        40        50        60
pF1KB4 MGGHFWPPEPYTVFMWGSPWEADSPRVKLRGREKGRQTEGGAFPLVSSALSGDPRFFSPT
                                     :. .::    :    : ...  .:    :.
NP_001 GVGPGLPGAGAPARPSPGRPPGAGRLRTGPGQVRGRLLAVGPKSRVFQSVVQEP----PA
      20        30        40        50        60        70         

                70        80        90       100       110         
pF1KB4 TPP-AEPIVVRLKEVRLQRDDFEILKVIGRGAFSEVAVVKMKQTGQVYAMKIMNKWDMLK
       .   ::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SESRAEPIVVRLKEVRLQRDDFEILKVIGRGAFSEVAVVKMKQTGQVYAMKIMNKWDMLK
          80        90       100       110       120       130     

     120       130       140       150       160       170         
pF1KB4 RGEVSCFREERDVLVNGDRRWITQLHFAFQDENYLYLVMEYYVGGDLLTLLSKFGERIPA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RGEVSCFREERDVLVNGDRRWITQLHFAFQDENYLYLVMEYYVGGDLLTLLSKFGERIPA
         140       150       160       170       180       190     

     180       190       200       210       220       230         
pF1KB4 EMARFYLAEIVMAIDSVHRLGYVHRDIKPDNILLDRCGHIRLADFGSCLKLRADGTVRSL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EMARFYLAEIVMAIDSVHRLGYVHRDIKPDNILLDRCGHIRLADFGSCLKLRADGTVRSL
         200       210       220       230       240       250     

     240       250       260       270       280       290         
pF1KB4 VAVGTPDYLSPEILQAVGGGPGTGSYGPECDWWALGVFAYEMFYGQTPFYADSTAETYGK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VAVGTPDYLSPEILQAVGGGPGTGSYGPECDWWALGVFAYEMFYGQTPFYADSTAETYGK
         260       270       280       290       300       310     

     300       310       320       330       340       350         
pF1KB4 IVHYKEHLSLPLVDEGVPEEARDFIQRLLCPPETRLGRGGAGDFRTHPFFFGLDWDGLRD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IVHYKEHLSLPLVDEGVPEEARDFIQRLLCPPETRLGRGGAGDFRTHPFFFGLDWDGLRD
         320       330       340       350       360       370     

     360       370       380            390       400       410    
pF1KB4 SVPPFTPDFEGATDTCNFDLVEDGLTAM-----ETLSDIREGAPLGVHLPFVGYSYSCMA
       ::::::::::::::::::::::::::::     :::::::::::::::::::::::::::
NP_001 SVPPFTPDFEGATDTCNFDLVEDGLTAMVSGGGETLSDIREGAPLGVHLPFVGYSYSCMA
         380       390       400       410       420       430     

          420       430       440       450       460       470    
pF1KB4 LRDSEVPGPTPMELEAEQLLEPHVQAPSLEPSVSPQDETAEVAVPAAVPAAEAEAEVTLR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LRDSEVPGPTPMELEAEQLLEPHVQAPSLEPSVSPQDETAEVAVPAAVPAAEAEAEVTLR
         440       450       460       470       480       490     

          480       490       500       510       520       530    
pF1KB4 ELQEALEEEVLTRQSLSREMEAIRTDNQNFASQLREAEARNRDLEAHVRQLQERMELLQA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ELQEALEEEVLTRQSLSREMEAIRTDNQNFASQLREAEARNRDLEAHVRQLQERMELLQA
         500       510       520       530       540       550     

          540       550       560       570       580       590    
pF1KB4 EGATAVTGVPSPRATDPPSHMAPRPWLWASARWWGQAPCTAATCCSLPGSLGLAYRRRFP
       ::::::::::::::::::::.   :                                   
NP_001 EGATAVTGVPSPRATDPPSHLDGPPAVAVGQCPLVGPGPMHRRHLLLPARVPRPGLSEAL
         560       570       580       590       600       610     

>>NP_004400 (OMIM: 160900,605377) myotonin-protein kinas  (629 aa)
 initn: 3290 init1: 2228 opt: 3288  Z-score: 1458.8  bits: 280.1 E(85289): 1.6e-74
Smith-Waterman score: 3288; 95.4% identity (96.5% similar) in 520 aa overlap (45-559:36-554)

           20        30        40        50        60        70    
pF1KB4 MWGSPWEADSPRVKLRGREKGRQTEGGAFPLVSSALSGDPRFFSPTTPPAEPIVVRLKEV
                                     : .: :. : .. .     :::::::::::
NP_004 RLRRLQQLVLDPGFLGLEPLLDLLLGVHQELGASELAQD-KYVADFLQWAEPIVVRLKEV
          10        20        30        40         50        60    

           80        90       100       110       120       130    
pF1KB4 RLQRDDFEILKVIGRGAFSEVAVVKMKQTGQVYAMKIMNKWDMLKRGEVSCFREERDVLV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 RLQRDDFEILKVIGRGAFSEVAVVKMKQTGQVYAMKIMNKWDMLKRGEVSCFREERDVLV
           70        80        90       100       110       120    

          140       150       160       170       180       190    
pF1KB4 NGDRRWITQLHFAFQDENYLYLVMEYYVGGDLLTLLSKFGERIPAEMARFYLAEIVMAID
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 NGDRRWITQLHFAFQDENYLYLVMEYYVGGDLLTLLSKFGERIPAEMARFYLAEIVMAID
          130       140       150       160       170       180    

          200       210       220       230       240       250    
pF1KB4 SVHRLGYVHRDIKPDNILLDRCGHIRLADFGSCLKLRADGTVRSLVAVGTPDYLSPEILQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 SVHRLGYVHRDIKPDNILLDRCGHIRLADFGSCLKLRADGTVRSLVAVGTPDYLSPEILQ
          190       200       210       220       230       240    

          260       270       280       290       300       310    
pF1KB4 AVGGGPGTGSYGPECDWWALGVFAYEMFYGQTPFYADSTAETYGKIVHYKEHLSLPLVDE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 AVGGGPGTGSYGPECDWWALGVFAYEMFYGQTPFYADSTAETYGKIVHYKEHLSLPLVDE
          250       260       270       280       290       300    

          320       330       340       350       360       370    
pF1KB4 GVPEEARDFIQRLLCPPETRLGRGGAGDFRTHPFFFGLDWDGLRDSVPPFTPDFEGATDT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 GVPEEARDFIQRLLCPPETRLGRGGAGDFRTHPFFFGLDWDGLRDSVPPFTPDFEGATDT
          310       320       330       340       350       360    

          380            390       400       410       420         
pF1KB4 CNFDLVEDGLTAM-----ETLSDIREGAPLGVHLPFVGYSYSCMALRDSEVPGPTPMELE
       :::::::::::::     ::::::::::::::::::::::::::::::::::::::::::
NP_004 CNFDLVEDGLTAMVSGGGETLSDIREGAPLGVHLPFVGYSYSCMALRDSEVPGPTPMELE
          370       380       390       400       410       420    

     430       440       450       460       470       480         
pF1KB4 AEQLLEPHVQAPSLEPSVSPQDETAEVAVPAAVPAAEAEAEVTLRELQEALEEEVLTRQS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 AEQLLEPHVQAPSLEPSVSPQDETAEVAVPAAVPAAEAEAEVTLRELQEALEEEVLTRQS
          430       440       450       460       470       480    

     490       500       510       520       530       540         
pF1KB4 LSREMEAIRTDNQNFASQLREAEARNRDLEAHVRQLQERMELLQAEGATAVTGVPSPRAT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 LSREMEAIRTDNQNFASQLREAEARNRDLEAHVRQLQERMELLQAEGATAVTGVPSPRAT
          490       500       510       520       530       540    

     550       560       570       580       590       600         
pF1KB4 DPPSHMAPRPWLWASARWWGQAPCTAATCCSLPGSLGLAYRRRFPCSCSPLFCLVPPPWA
       :::::.   :                                                  
NP_004 DPPSHLDGPPAVAVGQCPLVGPGPMHRRHLLLPARVPRPGLSEALSLLLFAVVLSRAAAL
          550       560       570       580       590       600    

>>NP_001275695 (OMIM: 160900,605377) myotonin-protein ki  (530 aa)
 initn: 3185 init1: 3185 opt: 3189  Z-score: 1416.4  bits: 272.0 E(85289): 3.7e-72
Smith-Waterman score: 3189; 97.0% identity (98.0% similar) in 494 aa overlap (45-538:36-528)

           20        30        40        50        60        70    
pF1KB4 MWGSPWEADSPRVKLRGREKGRQTEGGAFPLVSSALSGDPRFFSPTTPPAEPIVVRLKEV
                                     : .: :. : .. .     :::::::::::
NP_001 RLRRLQQLVLDPGFLGLEPLLDLLLGVHQELGASELAQD-KYVADFLQWAEPIVVRLKEV
          10        20        30        40         50        60    

           80        90       100       110       120       130    
pF1KB4 RLQRDDFEILKVIGRGAFSEVAVVKMKQTGQVYAMKIMNKWDMLKRGEVSCFREERDVLV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RLQRDDFEILKVIGRGAFSEVAVVKMKQTGQVYAMKIMNKWDMLKRGEVSCFREERDVLV
           70        80        90       100       110       120    

          140       150       160       170       180       190    
pF1KB4 NGDRRWITQLHFAFQDENYLYLVMEYYVGGDLLTLLSKFGERIPAEMARFYLAEIVMAID
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NGDRRWITQLHFAFQDENYLYLVMEYYVGGDLLTLLSKFGERIPAEMARFYLAEIVMAID
          130       140       150       160       170       180    

          200       210       220       230       240       250    
pF1KB4 SVHRLGYVHRDIKPDNILLDRCGHIRLADFGSCLKLRADGTVRSLVAVGTPDYLSPEILQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SVHRLGYVHRDIKPDNILLDRCGHIRLADFGSCLKLRADGTVRSLVAVGTPDYLSPEILQ
          190       200       210       220       230       240    

          260       270       280       290       300       310    
pF1KB4 AVGGGPGTGSYGPECDWWALGVFAYEMFYGQTPFYADSTAETYGKIVHYKEHLSLPLVDE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AVGGGPGTGSYGPECDWWALGVFAYEMFYGQTPFYADSTAETYGKIVHYKEHLSLPLVDE
          250       260       270       280       290       300    

          320       330       340       350       360       370    
pF1KB4 GVPEEARDFIQRLLCPPETRLGRGGAGDFRTHPFFFGLDWDGLRDSVPPFTPDFEGATDT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GVPEEARDFIQRLLCPPETRLGRGGAGDFRTHPFFFGLDWDGLRDSVPPFTPDFEGATDT
          310       320       330       340       350       360    

          380       390       400       410       420       430    
pF1KB4 CNFDLVEDGLTAMETLSDIREGAPLGVHLPFVGYSYSCMALRDSEVPGPTPMELEAEQLL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 CNFDLVEDGLTAMETLSDIREGAPLGVHLPFVGYSYSCMALRDSEVPGPTPMELEAEQLL
          370       380       390       400       410       420    

          440       450       460       470       480       490    
pF1KB4 EPHVQAPSLEPSVSPQDETAEVAVPAAVPAAEAEAEVTLRELQEALEEEVLTRQSLSREM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EPHVQAPSLEPSVSPQDETAEVAVPAAVPAAEAEAEVTLRELQEALEEEVLTRQSLSREM
          430       440       450       460       470       480    

          500       510       520       530       540       550    
pF1KB4 EAIRTDNQNFASQLREAEARNRDLEAHVRQLQERMELLQAEGATAVTGVPSPRATDPPSH
       ::::::::::::::::::::::::::::::::::::::::::::                
NP_001 EAIRTDNQNFASQLREAEARNRDLEAHVRQLQERMELLQAEGATGP              
          490       500       510       520       530              

          560       570       580       590       600       610    
pF1KB4 MAPRPWLWASARWWGQAPCTAATCCSLPGSLGLAYRRRFPCSCSPLFCLVPPPWAALGWW

>>XP_016858071 (OMIM: 603412) PREDICTED: serine/threonin  (1589 aa)
 initn: 1588 init1: 1013 opt: 1580  Z-score: 712.4  bits: 143.3 E(85289): 6.1e-33
Smith-Waterman score: 1611; 52.3% identity (75.5% similar) in 493 aa overlap (64-535:60-543)

            40        50        60        70        80        90   
pF1KB4 KGRQTEGGAFPLVSSALSGDPRFFSPTTPPAEPIVVRLKEVRLQRDDFEILKVIGRGAFS
                                     :.:.. ..:..::.:.:::::::::::::.
XP_016 TLLDILICLYDECNNSPLRREKNILEYLEWAKPFTSKVKQMRLHREDFEILKVIGRGAFG
      30        40        50        60        70        80         

           100       110       120       130       140       150   
pF1KB4 EVAVVKMKQTGQVYAMKIMNKWDMLKRGEVSCFREERDVLVNGDRRWITQLHFAFQDENY
       ::::::.:.. .:.::::.:::.::::.:..::::::::::::: .::: ::.::::.: 
XP_016 EVAVVKLKNADKVFAMKILNKWEMLKRAETACFREERDVLVNGDNKWITTLHYAFQDDNN
      90       100       110       120       130       140         

           160       170       180       190       200       210   
pF1KB4 LYLVMEYYVGGDLLTLLSKFGERIPAEMARFYLAEIVMAIDSVHRLGYVHRDIKPDNILL
       :::::.:::::::::::::: .:.: .::::::::.:.::::::.: ::::::::::::.
XP_016 LYLVMDYYVGGDLLTLLSKFEDRLPEDMARFYLAEMVIAIDSVHQLHYVHRDIKPDNILM
     150       160       170       180       190       200         

           220       230       240       250       260       270   
pF1KB4 DRCGHIRLADFGSCLKLRADGTVRSLVAVGTPDYLSPEILQAVGGGPGTGSYGPECDWWA
       :  ::::::::::::::  ::::.: ::::::::.:::::::.  : :   ::::::::.
XP_016 DMNGHIRLADFGSCLKLMEDGTVQSSVAVGTPDYISPEILQAMEDGKG--RYGPECDWWS
     210       220       230       240       250         260       

           280       290       300       310       320       330   
pF1KB4 LGVFAYEMFYGQTPFYADSTAETYGKIVHYKEHLSLPLVDEGVPEEARDFIQRLLCPPET
       :::  :::.::.:::::.: .::::::...::....:     : :.:.:.:.::.:  : 
XP_016 LGVCMYEMLYGETPFYAESLVETYGKIMNHKERFQFPAQVTDVSENAKDLIRRLICSREH
       270       280       290       300       310       320       

           340       350       360       370       380       390   
pF1KB4 RLGRGGAGDFRTHPFFFGLDWDGLRDSVPPFTPDFEGATDTCNFDLVEDGLTAMETLSDI
       :::..:  ::. :::: :.:::..:.   :. :.  . ::: :::. .: :   ::.   
XP_016 RLGQNGIEDFKKHPFFSGIDWDNIRNCEAPYIPEVSSPTDTSNFDVDDDCLKNSETMPPP
       330       340       350       360       370       380       

           400       410             420       430         440     
pF1KB4 REGAPLGVHLPFVGYSY--SCMALRDSE----VPGPTPMELEA--EQLLEPHVQAPSLEP
        . :  : ::::::..:  ::. : :      . ::: ..:..  .. :. .. . . : 
XP_016 THTAFSGHHLPFVGFTYTSSCV-LSDRSCLRVTAGPTSLDLDVNVQRTLDNNLATEAYER
       390       400        410       420       430       440      

          450       460       470       480             490        
pF1KB4 SVSP-QDETAEVAVPAAVPAAEAEAEVTLRELQEALEEEVLTR------QSLSREMEAIR
        ..  ..:  :..          :.  :.. :: .  .  ::       ..:..:.: .:
XP_016 RIKRLEQEKLELSRKLQ------ESTQTVQALQYSTVDGPLTASKDLEIKNLKEEIEKLR
        450       460             470       480       490       500

         500       510       520          530       540       550  
pF1KB4 ---TDNQNFASQLREAEARNRDLEAHVRQLQ---ERMELLQAEGATAVTGVPSPRATDPP
          :..... .::.::.:  ..:.   ::..   .... :: :                 
XP_016 KQVTESSHLEQQLEEANAVRQELDDAFRQIKAYEKQIKTLQQEREDLNKELVQASERLKN
              510       520       530       540       550       560

            560       570       580       590       600       610  
pF1KB4 SHMAPRPWLWASARWWGQAPCTAATCCSLPGSLGLAYRRRFPCSCSPLFCLVPPPWAALG
                                                                   
XP_016 QSKELKDAHCQRKLAMQEFMEINERLTELHTQKQKLARHVRDKEEEVDLVMQKVESLRQE
              570       580       590       600       610       620

>>NP_055641 (OMIM: 603412) serine/threonine-protein kina  (1638 aa)
 initn: 1585 init1: 1013 opt: 1580  Z-score: 712.3  bits: 143.4 E(85289): 6.2e-33
Smith-Waterman score: 1611; 52.3% identity (75.5% similar) in 493 aa overlap (64-535:60-543)

            40        50        60        70        80        90   
pF1KB4 KGRQTEGGAFPLVSSALSGDPRFFSPTTPPAEPIVVRLKEVRLQRDDFEILKVIGRGAFS
                                     :.:.. ..:..::.:.:::::::::::::.
NP_055 TLLDILICLYDECNNSPLRREKNILEYLEWAKPFTSKVKQMRLHREDFEILKVIGRGAFG
      30        40        50        60        70        80         

           100       110       120       130       140       150   
pF1KB4 EVAVVKMKQTGQVYAMKIMNKWDMLKRGEVSCFREERDVLVNGDRRWITQLHFAFQDENY
       ::::::.:.. .:.::::.:::.::::.:..::::::::::::: .::: ::.::::.: 
NP_055 EVAVVKLKNADKVFAMKILNKWEMLKRAETACFREERDVLVNGDNKWITTLHYAFQDDNN
      90       100       110       120       130       140         

           160       170       180       190       200       210   
pF1KB4 LYLVMEYYVGGDLLTLLSKFGERIPAEMARFYLAEIVMAIDSVHRLGYVHRDIKPDNILL
       :::::.:::::::::::::: .:.: .::::::::.:.::::::.: ::::::::::::.
NP_055 LYLVMDYYVGGDLLTLLSKFEDRLPEDMARFYLAEMVIAIDSVHQLHYVHRDIKPDNILM
     150       160       170       180       190       200         

           220       230       240       250       260       270   
pF1KB4 DRCGHIRLADFGSCLKLRADGTVRSLVAVGTPDYLSPEILQAVGGGPGTGSYGPECDWWA
       :  ::::::::::::::  ::::.: ::::::::.:::::::.  : :   ::::::::.
NP_055 DMNGHIRLADFGSCLKLMEDGTVQSSVAVGTPDYISPEILQAMEDGKG--RYGPECDWWS
     210       220       230       240       250         260       

           280       290       300       310       320       330   
pF1KB4 LGVFAYEMFYGQTPFYADSTAETYGKIVHYKEHLSLPLVDEGVPEEARDFIQRLLCPPET
       :::  :::.::.:::::.: .::::::...::....:     : :.:.:.:.::.:  : 
NP_055 LGVCMYEMLYGETPFYAESLVETYGKIMNHKERFQFPAQVTDVSENAKDLIRRLICSREH
       270       280       290       300       310       320       

           340       350       360       370       380       390   
pF1KB4 RLGRGGAGDFRTHPFFFGLDWDGLRDSVPPFTPDFEGATDTCNFDLVEDGLTAMETLSDI
       :::..:  ::. :::: :.:::..:.   :. :.  . ::: :::. .: :   ::.   
NP_055 RLGQNGIEDFKKHPFFSGIDWDNIRNCEAPYIPEVSSPTDTSNFDVDDDCLKNSETMPPP
       330       340       350       360       370       380       

           400       410             420       430         440     
pF1KB4 REGAPLGVHLPFVGYSY--SCMALRDSE----VPGPTPMELEA--EQLLEPHVQAPSLEP
        . :  : ::::::..:  ::. : :      . ::: ..:..  .. :. .. . . : 
NP_055 THTAFSGHHLPFVGFTYTSSCV-LSDRSCLRVTAGPTSLDLDVNVQRTLDNNLATEAYER
       390       400        410       420       430       440      

          450       460       470       480             490        
pF1KB4 SVSP-QDETAEVAVPAAVPAAEAEAEVTLRELQEALEEEVLTR------QSLSREMEAIR
        ..  ..:  :..          :.  :.. :: .  .  ::       ..:..:.: .:
NP_055 RIKRLEQEKLELSRKLQ------ESTQTVQALQYSTVDGPLTASKDLEIKNLKEEIEKLR
        450       460             470       480       490       500

         500       510       520          530       540       550  
pF1KB4 ---TDNQNFASQLREAEARNRDLEAHVRQLQ---ERMELLQAEGATAVTGVPSPRATDPP
          :..... .::.::.:  ..:.   ::..   .... :: :                 
NP_055 KQVTESSHLEQQLEEANAVRQELDDAFRQIKAYEKQIKTLQQEREDLNKLEVHTEALAAE
              510       520       530       540       550       560

            560       570       580       590       600       610  
pF1KB4 SHMAPRPWLWASARWWGQAPCTAATCCSLPGSLGLAYRRRFPCSCSPLFCLVPPPWAALG
                                                                   
NP_055 ASKDRKLREQSEHYSKQLENELEGLKQKQISYSPGVCSIEHQQEITKLKTDLEKKSIFYE
              570       580       590       600       610       620

>>NP_003598 (OMIM: 603412) serine/threonine-protein kina  (1719 aa)
 initn: 1585 init1: 1013 opt: 1580  Z-score: 712.1  bits: 143.4 E(85289): 6.3e-33
Smith-Waterman score: 1611; 52.3% identity (75.5% similar) in 493 aa overlap (64-535:60-543)

            40        50        60        70        80        90   
pF1KB4 KGRQTEGGAFPLVSSALSGDPRFFSPTTPPAEPIVVRLKEVRLQRDDFEILKVIGRGAFS
                                     :.:.. ..:..::.:.:::::::::::::.
NP_003 TLLDILICLYDECNNSPLRREKNILEYLEWAKPFTSKVKQMRLHREDFEILKVIGRGAFG
      30        40        50        60        70        80         

           100       110       120       130       140       150   
pF1KB4 EVAVVKMKQTGQVYAMKIMNKWDMLKRGEVSCFREERDVLVNGDRRWITQLHFAFQDENY
       ::::::.:.. .:.::::.:::.::::.:..::::::::::::: .::: ::.::::.: 
NP_003 EVAVVKLKNADKVFAMKILNKWEMLKRAETACFREERDVLVNGDNKWITTLHYAFQDDNN
      90       100       110       120       130       140         

           160       170       180       190       200       210   
pF1KB4 LYLVMEYYVGGDLLTLLSKFGERIPAEMARFYLAEIVMAIDSVHRLGYVHRDIKPDNILL
       :::::.:::::::::::::: .:.: .::::::::.:.::::::.: ::::::::::::.
NP_003 LYLVMDYYVGGDLLTLLSKFEDRLPEDMARFYLAEMVIAIDSVHQLHYVHRDIKPDNILM
     150       160       170       180       190       200         

           220       230       240       250       260       270   
pF1KB4 DRCGHIRLADFGSCLKLRADGTVRSLVAVGTPDYLSPEILQAVGGGPGTGSYGPECDWWA
       :  ::::::::::::::  ::::.: ::::::::.:::::::.  : :   ::::::::.
NP_003 DMNGHIRLADFGSCLKLMEDGTVQSSVAVGTPDYISPEILQAMEDGKG--RYGPECDWWS
     210       220       230       240       250         260       

           280       290       300       310       320       330   
pF1KB4 LGVFAYEMFYGQTPFYADSTAETYGKIVHYKEHLSLPLVDEGVPEEARDFIQRLLCPPET
       :::  :::.::.:::::.: .::::::...::....:     : :.:.:.:.::.:  : 
NP_003 LGVCMYEMLYGETPFYAESLVETYGKIMNHKERFQFPAQVTDVSENAKDLIRRLICSREH
       270       280       290       300       310       320       

           340       350       360       370       380       390   
pF1KB4 RLGRGGAGDFRTHPFFFGLDWDGLRDSVPPFTPDFEGATDTCNFDLVEDGLTAMETLSDI
       :::..:  ::. :::: :.:::..:.   :. :.  . ::: :::. .: :   ::.   
NP_003 RLGQNGIEDFKKHPFFSGIDWDNIRNCEAPYIPEVSSPTDTSNFDVDDDCLKNSETMPPP
       330       340       350       360       370       380       

           400       410             420       430         440     
pF1KB4 REGAPLGVHLPFVGYSY--SCMALRDSE----VPGPTPMELEA--EQLLEPHVQAPSLEP
        . :  : ::::::..:  ::. : :      . ::: ..:..  .. :. .. . . : 
NP_003 THTAFSGHHLPFVGFTYTSSCV-LSDRSCLRVTAGPTSLDLDVNVQRTLDNNLATEAYER
       390       400        410       420       430       440      

          450       460       470       480             490        
pF1KB4 SVSP-QDETAEVAVPAAVPAAEAEAEVTLRELQEALEEEVLTR------QSLSREMEAIR
        ..  ..:  :..          :.  :.. :: .  .  ::       ..:..:.: .:
NP_003 RIKRLEQEKLELSRKLQ------ESTQTVQALQYSTVDGPLTASKDLEIKNLKEEIEKLR
        450       460             470       480       490       500

         500       510       520          530       540       550  
pF1KB4 ---TDNQNFASQLREAEARNRDLEAHVRQLQ---ERMELLQAEGATAVTGVPSPRATDPP
          :..... .::.::.:  ..:.   ::..   .... :: :                 
NP_003 KQVTESSHLEQQLEEANAVRQELDDAFRQIKAYEKQIKTLQQEREDLNKELVQASERLKN
              510       520       530       540       550       560

            560       570       580       590       600       610  
pF1KB4 SHMAPRPWLWASARWWGQAPCTAATCCSLPGSLGLAYRRRFPCSCSPLFCLVPPPWAALG
                                                                   
NP_003 QSKELKDAHCQRKLAMQEFMEINERLTELHTQKQKLARHVRDKEEEVDLVMQKVESLRQE
              570       580       590       600       610       620




635 residues in 1 query   sequences
60827320 residues in 85289 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Thu Nov  3 14:43:18 2016 done: Thu Nov  3 14:43:20 2016
 Total Scan time: 12.830 Total Display time:  0.120

Function used was FASTA [36.3.4 Apr, 2011]
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