Result of FASTA (omim) for pF1KB4221
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KB4221, 561 aa
  1>>>pF1KB4221 561 - 561 aa - 561 aa
Library: /omim/omim.rfq.tfa
  60827320 residues in 85289 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 13.7017+/-0.000432; mu= -19.5708+/- 0.027
 mean_var=547.0957+/-110.697, 0's: 0 Z-trim(124.5): 20  B-trim: 0 in 0/61
 Lambda= 0.054833
 statistics sampled from 46319 (46379) to 46319 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.814), E-opt: 0.2 (0.544), width:  16
 Scan time: 13.680

The best scores are:                                      opt bits E(85289)
NP_001116153 (OMIM: 118400,602104) SH3 domain-bind ( 561) 3943 326.6 1.3e-88
NP_003014 (OMIM: 118400,602104) SH3 domain-binding ( 561) 3943 326.6 1.3e-88
NP_001139327 (OMIM: 118400,602104) SH3 domain-bind ( 589) 3943 326.6 1.4e-88
NP_001139328 (OMIM: 118400,602104) SH3 domain-bind ( 618) 3943 326.6 1.4e-88


>>NP_001116153 (OMIM: 118400,602104) SH3 domain-binding   (561 aa)
 initn: 3943 init1: 3943 opt: 3943  Z-score: 1711.8  bits: 326.6 E(85289): 1.3e-88
Smith-Waterman score: 3943; 100.0% identity (100.0% similar) in 561 aa overlap (1-561:1-561)

               10        20        30        40        50        60
pF1KB4 MAAEEMHWPVPMKAIGAQNLLTMPGGVAKAGYLHKKGGTQLQLLKWPLRFVIIHKRCVYY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MAAEEMHWPVPMKAIGAQNLLTMPGGVAKAGYLHKKGGTQLQLLKWPLRFVIIHKRCVYY
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB4 FKSSTSASPQGAFSLSGYNRVMRAAEETTSNNVFPFKIIHISKKHRTWFFSASSEEERKS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FKSSTSASPQGAFSLSGYNRVMRAAEETTSNNVFPFKIIHISKKHRTWFFSASSEEERKS
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB4 WMALLRREIGHFHEKKDLPLDTSDSSSDTDSFYGAVERPVDISLSPYPTDNEDYEHDDED
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 WMALLRREIGHFHEKKDLPLDTSDSSSDTDSFYGAVERPVDISLSPYPTDNEDYEHDDED
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB4 DSYLEPDSPEPGRLEDALMHPPAYPPPPVPTPRKPAFSDMPRAHSFTSKGPGPLLPPPPP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DSYLEPDSPEPGRLEDALMHPPAYPPPPVPTPRKPAFSDMPRAHSFTSKGPGPLLPPPPP
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB4 KHGLPDVGLAAEDSKRDPLCPRRAEPCPRVPATPRRMSDPPLSTMPTAPGLRKPPCFRES
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KHGLPDVGLAAEDSKRDPLCPRRAEPCPRVPATPRRMSDPPLSTMPTAPGLRKPPCFRES
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KB4 ASPSPEPWTPGHGACSTSSAAIMATATSRNCDKLKSFHLSPRGPPTSEPPPVPANKPKFL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ASPSPEPWTPGHGACSTSSAAIMATATSRNCDKLKSFHLSPRGPPTSEPPPVPANKPKFL
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KB4 KIAEEDPPREAAMPGLFVPPVAPRPPALKLPVPEAMARPAVLPRPEKPQLPHLQRSPPDG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KIAEEDPPREAAMPGLFVPPVAPRPPALKLPVPEAMARPAVLPRPEKPQLPHLQRSPPDG
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KB4 QSFRSFSFEKPRQPSQADTGGDDSDEDYEKVPLPNSVFVNTTESCEVERLFKATSPRGEP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QSFRSFSFEKPRQPSQADTGGDDSDEDYEKVPLPNSVFVNTTESCEVERLFKATSPRGEP
              430       440       450       460       470       480

              490       500       510       520       530       540
pF1KB4 QDGLYCIRNSSTKSGKVLVVWDETSNKVRNYRIFEKDSKFYLEGEVLFVSVGSMVEHYHT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QDGLYCIRNSSTKSGKVLVVWDETSNKVRNYRIFEKDSKFYLEGEVLFVSVGSMVEHYHT
              490       500       510       520       530       540

              550       560 
pF1KB4 HVLPSHQSLLLRHPYGYTGPR
       :::::::::::::::::::::
NP_001 HVLPSHQSLLLRHPYGYTGPR
              550       560 

>>NP_003014 (OMIM: 118400,602104) SH3 domain-binding pro  (561 aa)
 initn: 3943 init1: 3943 opt: 3943  Z-score: 1711.8  bits: 326.6 E(85289): 1.3e-88
Smith-Waterman score: 3943; 100.0% identity (100.0% similar) in 561 aa overlap (1-561:1-561)

               10        20        30        40        50        60
pF1KB4 MAAEEMHWPVPMKAIGAQNLLTMPGGVAKAGYLHKKGGTQLQLLKWPLRFVIIHKRCVYY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 MAAEEMHWPVPMKAIGAQNLLTMPGGVAKAGYLHKKGGTQLQLLKWPLRFVIIHKRCVYY
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB4 FKSSTSASPQGAFSLSGYNRVMRAAEETTSNNVFPFKIIHISKKHRTWFFSASSEEERKS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 FKSSTSASPQGAFSLSGYNRVMRAAEETTSNNVFPFKIIHISKKHRTWFFSASSEEERKS
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB4 WMALLRREIGHFHEKKDLPLDTSDSSSDTDSFYGAVERPVDISLSPYPTDNEDYEHDDED
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 WMALLRREIGHFHEKKDLPLDTSDSSSDTDSFYGAVERPVDISLSPYPTDNEDYEHDDED
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB4 DSYLEPDSPEPGRLEDALMHPPAYPPPPVPTPRKPAFSDMPRAHSFTSKGPGPLLPPPPP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 DSYLEPDSPEPGRLEDALMHPPAYPPPPVPTPRKPAFSDMPRAHSFTSKGPGPLLPPPPP
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB4 KHGLPDVGLAAEDSKRDPLCPRRAEPCPRVPATPRRMSDPPLSTMPTAPGLRKPPCFRES
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 KHGLPDVGLAAEDSKRDPLCPRRAEPCPRVPATPRRMSDPPLSTMPTAPGLRKPPCFRES
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KB4 ASPSPEPWTPGHGACSTSSAAIMATATSRNCDKLKSFHLSPRGPPTSEPPPVPANKPKFL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 ASPSPEPWTPGHGACSTSSAAIMATATSRNCDKLKSFHLSPRGPPTSEPPPVPANKPKFL
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KB4 KIAEEDPPREAAMPGLFVPPVAPRPPALKLPVPEAMARPAVLPRPEKPQLPHLQRSPPDG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 KIAEEDPPREAAMPGLFVPPVAPRPPALKLPVPEAMARPAVLPRPEKPQLPHLQRSPPDG
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KB4 QSFRSFSFEKPRQPSQADTGGDDSDEDYEKVPLPNSVFVNTTESCEVERLFKATSPRGEP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 QSFRSFSFEKPRQPSQADTGGDDSDEDYEKVPLPNSVFVNTTESCEVERLFKATSPRGEP
              430       440       450       460       470       480

              490       500       510       520       530       540
pF1KB4 QDGLYCIRNSSTKSGKVLVVWDETSNKVRNYRIFEKDSKFYLEGEVLFVSVGSMVEHYHT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 QDGLYCIRNSSTKSGKVLVVWDETSNKVRNYRIFEKDSKFYLEGEVLFVSVGSMVEHYHT
              490       500       510       520       530       540

              550       560 
pF1KB4 HVLPSHQSLLLRHPYGYTGPR
       :::::::::::::::::::::
NP_003 HVLPSHQSLLLRHPYGYTGPR
              550       560 

>>NP_001139327 (OMIM: 118400,602104) SH3 domain-binding   (589 aa)
 initn: 3943 init1: 3943 opt: 3943  Z-score: 1711.5  bits: 326.6 E(85289): 1.4e-88
Smith-Waterman score: 3943; 100.0% identity (100.0% similar) in 561 aa overlap (1-561:29-589)

                                           10        20        30  
pF1KB4                             MAAEEMHWPVPMKAIGAQNLLTMPGGVAKAGY
                                   ::::::::::::::::::::::::::::::::
NP_001 MASLGPRTPAPSRSRGRRAMCWVSTISFMAAEEMHWPVPMKAIGAQNLLTMPGGVAKAGY
               10        20        30        40        50        60

             40        50        60        70        80        90  
pF1KB4 LHKKGGTQLQLLKWPLRFVIIHKRCVYYFKSSTSASPQGAFSLSGYNRVMRAAEETTSNN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LHKKGGTQLQLLKWPLRFVIIHKRCVYYFKSSTSASPQGAFSLSGYNRVMRAAEETTSNN
               70        80        90       100       110       120

            100       110       120       130       140       150  
pF1KB4 VFPFKIIHISKKHRTWFFSASSEEERKSWMALLRREIGHFHEKKDLPLDTSDSSSDTDSF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VFPFKIIHISKKHRTWFFSASSEEERKSWMALLRREIGHFHEKKDLPLDTSDSSSDTDSF
              130       140       150       160       170       180

            160       170       180       190       200       210  
pF1KB4 YGAVERPVDISLSPYPTDNEDYEHDDEDDSYLEPDSPEPGRLEDALMHPPAYPPPPVPTP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 YGAVERPVDISLSPYPTDNEDYEHDDEDDSYLEPDSPEPGRLEDALMHPPAYPPPPVPTP
              190       200       210       220       230       240

            220       230       240       250       260       270  
pF1KB4 RKPAFSDMPRAHSFTSKGPGPLLPPPPPKHGLPDVGLAAEDSKRDPLCPRRAEPCPRVPA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RKPAFSDMPRAHSFTSKGPGPLLPPPPPKHGLPDVGLAAEDSKRDPLCPRRAEPCPRVPA
              250       260       270       280       290       300

            280       290       300       310       320       330  
pF1KB4 TPRRMSDPPLSTMPTAPGLRKPPCFRESASPSPEPWTPGHGACSTSSAAIMATATSRNCD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TPRRMSDPPLSTMPTAPGLRKPPCFRESASPSPEPWTPGHGACSTSSAAIMATATSRNCD
              310       320       330       340       350       360

            340       350       360       370       380       390  
pF1KB4 KLKSFHLSPRGPPTSEPPPVPANKPKFLKIAEEDPPREAAMPGLFVPPVAPRPPALKLPV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KLKSFHLSPRGPPTSEPPPVPANKPKFLKIAEEDPPREAAMPGLFVPPVAPRPPALKLPV
              370       380       390       400       410       420

            400       410       420       430       440       450  
pF1KB4 PEAMARPAVLPRPEKPQLPHLQRSPPDGQSFRSFSFEKPRQPSQADTGGDDSDEDYEKVP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PEAMARPAVLPRPEKPQLPHLQRSPPDGQSFRSFSFEKPRQPSQADTGGDDSDEDYEKVP
              430       440       450       460       470       480

            460       470       480       490       500       510  
pF1KB4 LPNSVFVNTTESCEVERLFKATSPRGEPQDGLYCIRNSSTKSGKVLVVWDETSNKVRNYR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LPNSVFVNTTESCEVERLFKATSPRGEPQDGLYCIRNSSTKSGKVLVVWDETSNKVRNYR
              490       500       510       520       530       540

            520       530       540       550       560 
pF1KB4 IFEKDSKFYLEGEVLFVSVGSMVEHYHTHVLPSHQSLLLRHPYGYTGPR
       :::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IFEKDSKFYLEGEVLFVSVGSMVEHYHTHVLPSHQSLLLRHPYGYTGPR
              550       560       570       580         

>>NP_001139328 (OMIM: 118400,602104) SH3 domain-binding   (618 aa)
 initn: 3943 init1: 3943 opt: 3943  Z-score: 1711.2  bits: 326.6 E(85289): 1.4e-88
Smith-Waterman score: 3943; 100.0% identity (100.0% similar) in 561 aa overlap (1-561:58-618)

                                             10        20        30
pF1KB4                               MAAEEMHWPVPMKAIGAQNLLTMPGGVAKA
                                     ::::::::::::::::::::::::::::::
NP_001 RGPGPCRCSQGRRAWIAPGKPAMPAAWTPFMAAEEMHWPVPMKAIGAQNLLTMPGGVAKA
        30        40        50        60        70        80       

               40        50        60        70        80        90
pF1KB4 GYLHKKGGTQLQLLKWPLRFVIIHKRCVYYFKSSTSASPQGAFSLSGYNRVMRAAEETTS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GYLHKKGGTQLQLLKWPLRFVIIHKRCVYYFKSSTSASPQGAFSLSGYNRVMRAAEETTS
        90       100       110       120       130       140       

              100       110       120       130       140       150
pF1KB4 NNVFPFKIIHISKKHRTWFFSASSEEERKSWMALLRREIGHFHEKKDLPLDTSDSSSDTD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NNVFPFKIIHISKKHRTWFFSASSEEERKSWMALLRREIGHFHEKKDLPLDTSDSSSDTD
       150       160       170       180       190       200       

              160       170       180       190       200       210
pF1KB4 SFYGAVERPVDISLSPYPTDNEDYEHDDEDDSYLEPDSPEPGRLEDALMHPPAYPPPPVP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SFYGAVERPVDISLSPYPTDNEDYEHDDEDDSYLEPDSPEPGRLEDALMHPPAYPPPPVP
       210       220       230       240       250       260       

              220       230       240       250       260       270
pF1KB4 TPRKPAFSDMPRAHSFTSKGPGPLLPPPPPKHGLPDVGLAAEDSKRDPLCPRRAEPCPRV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TPRKPAFSDMPRAHSFTSKGPGPLLPPPPPKHGLPDVGLAAEDSKRDPLCPRRAEPCPRV
       270       280       290       300       310       320       

              280       290       300       310       320       330
pF1KB4 PATPRRMSDPPLSTMPTAPGLRKPPCFRESASPSPEPWTPGHGACSTSSAAIMATATSRN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PATPRRMSDPPLSTMPTAPGLRKPPCFRESASPSPEPWTPGHGACSTSSAAIMATATSRN
       330       340       350       360       370       380       

              340       350       360       370       380       390
pF1KB4 CDKLKSFHLSPRGPPTSEPPPVPANKPKFLKIAEEDPPREAAMPGLFVPPVAPRPPALKL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 CDKLKSFHLSPRGPPTSEPPPVPANKPKFLKIAEEDPPREAAMPGLFVPPVAPRPPALKL
       390       400       410       420       430       440       

              400       410       420       430       440       450
pF1KB4 PVPEAMARPAVLPRPEKPQLPHLQRSPPDGQSFRSFSFEKPRQPSQADTGGDDSDEDYEK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PVPEAMARPAVLPRPEKPQLPHLQRSPPDGQSFRSFSFEKPRQPSQADTGGDDSDEDYEK
       450       460       470       480       490       500       

              460       470       480       490       500       510
pF1KB4 VPLPNSVFVNTTESCEVERLFKATSPRGEPQDGLYCIRNSSTKSGKVLVVWDETSNKVRN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VPLPNSVFVNTTESCEVERLFKATSPRGEPQDGLYCIRNSSTKSGKVLVVWDETSNKVRN
       510       520       530       540       550       560       

              520       530       540       550       560 
pF1KB4 YRIFEKDSKFYLEGEVLFVSVGSMVEHYHTHVLPSHQSLLLRHPYGYTGPR
       :::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 YRIFEKDSKFYLEGEVLFVSVGSMVEHYHTHVLPSHQSLLLRHPYGYTGPR
       570       580       590       600       610        




561 residues in 1 query   sequences
60827320 residues in 85289 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Thu Nov  3 14:37:51 2016 done: Thu Nov  3 14:37:53 2016
 Total Scan time: 13.680 Total Display time:  0.050

Function used was FASTA [36.3.4 Apr, 2011]
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