Result of FASTA (omim) for pF1KB3492
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KB3492, 397 aa
  1>>>pF1KB3492 397 - 397 aa - 397 aa
Library: /omim/omim.rfq.tfa
  60827320 residues in 85289 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 5.7026+/-0.000408; mu= 14.2790+/- 0.025
 mean_var=60.8622+/-12.346, 0's: 0 Z-trim(109.9): 49  B-trim: 873 in 1/57
 Lambda= 0.164399
 statistics sampled from 18137 (18168) to 18137 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.561), E-opt: 0.2 (0.213), width:  16
 Scan time:  7.700

The best scores are:                                      opt bits E(85289)
NP_005882 (OMIM: 100678,614055) acetyl-CoA acetylt ( 397) 2583 621.5 1.1e-177
NP_001290182 (OMIM: 100678,614055) acetyl-CoA acet ( 426) 2469 594.4 1.6e-169
NP_000010 (OMIM: 203750,607809) acetyl-CoA acetylt ( 427) 1030 253.1   9e-67
NP_006102 (OMIM: 604770) 3-ketoacyl-CoA thiolase,  ( 397) 1001 246.3 9.9e-65
XP_006718898 (OMIM: 203750,607809) PREDICTED: acet ( 337)  897 221.6 2.3e-57
XP_016873170 (OMIM: 203750,607809) PREDICTED: acet ( 337)  897 221.6 2.3e-57
NP_001598 (OMIM: 604054) 3-ketoacyl-CoA thiolase,  ( 424)  841 208.3 2.8e-53
XP_016873171 (OMIM: 203750,607809) PREDICTED: acet ( 301)  723 180.3 5.4e-45
XP_016873172 (OMIM: 203750,607809) PREDICTED: acet ( 301)  723 180.3 5.4e-45
XP_006713186 (OMIM: 604054) PREDICTED: 3-ketoacyl- ( 272)  699 174.6 2.5e-43
XP_011531952 (OMIM: 604054) PREDICTED: 3-ketoacyl- ( 279)  699 174.6 2.6e-43
NP_001123882 (OMIM: 604054) 3-ketoacyl-CoA thiolas ( 331)  350 91.8 2.5e-18
XP_006713185 (OMIM: 604054) PREDICTED: 3-ketoacyl- ( 364)  350 91.9 2.8e-18
NP_001268442 (OMIM: 143450,609015) trifunctional e ( 452)  199 56.1   2e-07
NP_000174 (OMIM: 143450,609015) trifunctional enzy ( 474)  199 56.1 2.1e-07
XP_011531105 (OMIM: 143450,609015) PREDICTED: trif ( 474)  199 56.1 2.1e-07
XP_016859428 (OMIM: 143450,609015) PREDICTED: trif ( 481)  199 56.1 2.2e-07
NP_001268441 (OMIM: 143450,609015) trifunctional e ( 459)  180 51.6 4.7e-06


>>NP_005882 (OMIM: 100678,614055) acetyl-CoA acetyltrans  (397 aa)
 initn: 2583 init1: 2583 opt: 2583  Z-score: 3310.9  bits: 621.5 E(85289): 1.1e-177
Smith-Waterman score: 2583; 99.7% identity (100.0% similar) in 397 aa overlap (1-397:1-397)

               10        20        30        40        50        60
pF1KB3 MNAGSDPVVIVSAARTIIGSFNGALAAVPVQDLGSTVIKEVLKRATVAPEDVSEVIFGHV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 MNAGSDPVVIVSAARTIIGSFNGALAAVPVQDLGSTVIKEVLKRATVAPEDVSEVIFGHV
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB3 LAAGCGQNPVRQASVGAGIPYSVPAWSCQMICGSGLKAVCLAVQSIGIGDSSIVVAGGME
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 LAAGCGQNPVRQASVGAGIPYSVPAWSCQMICGSGLKAVCLAVQSIGIGDSSIVVAGGME
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB3 NMSKAPHLAYLRTGVKIGEMPLTDSILCDGLTDAFHNCHMGITAENVAKKWQVSREDQDK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 NMSKAPHLAYLRTGVKIGEMPLTDSILCDGLTDAFHNCHMGITAENVAKKWQVSREDQDK
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB3 VAVLSQNRTENAQKAGHFDKEIVPVLVSTRRGLIEVKTDEFPRHGSNIEAMSKLKPYFLT
       ::::::::::::::::::::::::::::::.:::::::::::::::::::::::::::::
NP_005 VAVLSQNRTENAQKAGHFDKEIVPVLVSTRKGLIEVKTDEFPRHGSNIEAMSKLKPYFLT
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB3 DGTGTVTPANASGINDGAAAVVLMKKSEADKRGLTPLARIVSWSQVGVEPSIMGIGPIPA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 DGTGTVTPANASGINDGAAAVVLMKKSEADKRGLTPLARIVSWSQVGVEPSIMGIGPIPA
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KB3 IKQAVTKAGWSLEDVDIFEINEAFAAVSAAIVKELGLNPEKVNIEGGAIALGHPLGASGC
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 IKQAVTKAGWSLEDVDIFEINEAFAAVSAAIVKELGLNPEKVNIEGGAIALGHPLGASGC
              310       320       330       340       350       360

              370       380       390       
pF1KB3 RILVTLLHTLERMGRSRGVAALCIGGGMGIAMCVQRE
       :::::::::::::::::::::::::::::::::::::
NP_005 RILVTLLHTLERMGRSRGVAALCIGGGMGIAMCVQRE
              370       380       390       

>>NP_001290182 (OMIM: 100678,614055) acetyl-CoA acetyltr  (426 aa)
 initn: 2468 init1: 2468 opt: 2469  Z-score: 3164.3  bits: 594.4 E(85289): 1.6e-169
Smith-Waterman score: 2469; 98.7% identity (99.2% similar) in 384 aa overlap (14-397:43-426)

                                10        20        30        40   
pF1KB3                  MNAGSDPVVIVSAARTIIGSFNGALAAVPVQDLGSTVIKEVLK
                                     :.:   ::::::::::::::::::::::::
NP_001 RRATAASLGRSGGRLSSPRLLRVVAPTLTFAQTSRCSFNGALAAVPVQDLGSTVIKEVLK
             20        30        40        50        60        70  

            50        60        70        80        90       100   
pF1KB3 RATVAPEDVSEVIFGHVLAAGCGQNPVRQASVGAGIPYSVPAWSCQMICGSGLKAVCLAV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RATVAPEDVSEVIFGHVLAAGCGQNPVRQASVGAGIPYSVPAWSCQMICGSGLKAVCLAV
             80        90       100       110       120       130  

           110       120       130       140       150       160   
pF1KB3 QSIGIGDSSIVVAGGMENMSKAPHLAYLRTGVKIGEMPLTDSILCDGLTDAFHNCHMGIT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QSIGIGDSSIVVAGGMENMSKAPHLAYLRTGVKIGEMPLTDSILCDGLTDAFHNCHMGIT
            140       150       160       170       180       190  

           170       180       190       200       210       220   
pF1KB3 AENVAKKWQVSREDQDKVAVLSQNRTENAQKAGHFDKEIVPVLVSTRRGLIEVKTDEFPR
       :::::::::::::::::::::::::::::::::::::::::::::::.::::::::::::
NP_001 AENVAKKWQVSREDQDKVAVLSQNRTENAQKAGHFDKEIVPVLVSTRKGLIEVKTDEFPR
            200       210       220       230       240       250  

           230       240       250       260       270       280   
pF1KB3 HGSNIEAMSKLKPYFLTDGTGTVTPANASGINDGAAAVVLMKKSEADKRGLTPLARIVSW
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 HGSNIEAMSKLKPYFLTDGTGTVTPANASGINDGAAAVVLMKKSEADKRGLTPLARIVSW
            260       270       280       290       300       310  

           290       300       310       320       330       340   
pF1KB3 SQVGVEPSIMGIGPIPAIKQAVTKAGWSLEDVDIFEINEAFAAVSAAIVKELGLNPEKVN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SQVGVEPSIMGIGPIPAIKQAVTKAGWSLEDVDIFEINEAFAAVSAAIVKELGLNPEKVN
            320       330       340       350       360       370  

           350       360       370       380       390       
pF1KB3 IEGGAIALGHPLGASGCRILVTLLHTLERMGRSRGVAALCIGGGMGIAMCVQRE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IEGGAIALGHPLGASGCRILVTLLHTLERMGRSRGVAALCIGGGMGIAMCVQRE
            380       390       400       410       420      

>>NP_000010 (OMIM: 203750,607809) acetyl-CoA acetyltrans  (427 aa)
 initn: 993 init1: 395 opt: 1030  Z-score: 1319.8  bits: 253.1 E(85289): 9e-67
Smith-Waterman score: 1030; 43.8% identity (74.4% similar) in 390 aa overlap (8-396:42-426)

                                      10        20        30       
pF1KB3                        MNAGSDPVVIVSAARTIIGSFNGALAAVPVQDLGSTV
                                     ::::::.:: :::: :.:. .:.  ::: .
NP_000 ARSRSPLLRRLVQEIRYVERSYVSKPTLKEVVIVSATRTPIGSFLGSLSLLPATKLGSIA
              20        30        40        50        60        70 

        40        50        60        70        80        90       
pF1KB3 IKEVLKRATVAPEDVSEVIFGHVLAAGCGQNPVRQASVGAGIPYSVPAWSCQMICGSGLK
       :. ....: .  :.:.:. .:.:: .: :: :.::: .:::.: :.:  . . .:.::.:
NP_000 IQGAIEKAGIPKEEVKEAYMGNVLQGGEGQAPTRQAVLGAGLPISTPCTTINKVCASGMK
              80        90       100       110       120       130 

       100       110       120       130       140       150       
pF1KB3 AVCLAVQSIGIGDSSIVVAGGMENMSKAPHLAYLRTGVKIGEMPLTDSILCDGLTDAFHN
       :. .: ::.  : ....::::::.::..:..   : ..  : . : : :. :::::....
NP_000 AIMMASQSLMCGHQDVMVAGGMESMSNVPYVMN-RGSTPYGGVKLEDLIVKDGLTDVYNK
             140       150       160        170       180       190

       160       170       180       190       200       210       
pF1KB3 CHMGITAENVAKKWQVSREDQDKVAVLSQNRTENAQKAGHFDKEIVPVLVSTR-RGLIEV
        :::  :::.::: ...:..::  :. : .:.. : .::.: .:..:: :... .  . :
NP_000 IHMGSCAENTAKKLNIARNEQDAYAINSYTRSKAAWEAGKFGNEVIPVTVTVKGQPDVVV
              200       210       220       230       240       250

        220       230       240       250       260       270      
pF1KB3 KTDEFPRHGSNIEAMSKLKPYFLTDGTGTVTPANASGINDGAAAVVLMKKSEADKRGLTP
       : ::  ..  ..  . :::  :  .. :::: :::: .::::::.:::  . : . ..::
NP_000 KEDEEYKR-VDFSKVPKLKTVFQKEN-GTVTAANASTLNDGAAALVLMTADAAKRLNVTP
               260       270        280       290       300        

        280       290       300       310       320       330      
pF1KB3 LARIVSWSQVGVEPSIMGIGPIPAIKQAVTKAGWSLEDVDIFEINEAFAAVSAAIVKELG
       :::::......:::  . :.:. : ....  .: . ::. ..:.::::. :  : .: : 
NP_000 LARIVAFADAAVEPIDFPIAPVYAASMVLKDVGLKKEDIAMWEVNEAFSLVVLANIKMLE
      310       320       330       340       350       360        

        340       350       360       370       380       390      
pF1KB3 LNPEKVNIEGGAIALGHPLGASGCRILVTLLHTLERMGRSRGVAALCIGGGMGIAMCVQR
       ..:.::::.:::..::::.: :: ::.  : :.: ..:.  :.:..: ::: . :: .:.
NP_000 IDPQKVNINGGAVSLGHPIGMSGARIVGHLTHAL-KQGE-YGLASICNGGGGASAMLIQK
      370       380       390       400         410       420      

        
pF1KB3 E
        
NP_000 L
        

>>NP_006102 (OMIM: 604770) 3-ketoacyl-CoA thiolase, mito  (397 aa)
 initn: 1023 init1: 534 opt: 1001  Z-score: 1283.1  bits: 246.3 E(85289): 9.9e-65
Smith-Waterman score: 1001; 42.7% identity (72.1% similar) in 391 aa overlap (8-395:7-394)

               10        20        30        40        50        60
pF1KB3 MNAGSDPVVIVSAARTIIGSFNGALAAVPVQDLGSTVIKEVLKRATVAPEDVSEVIFGHV
              : .:.: :: .:...: :    . ::.  . : .:. . :.:: :. ::.:.:
NP_006  MALLRGVFVVAAKRTPFGAYGGLLKDFTATDLSEFAAKAALSAGKVSPETVDSVIMGNV
                10        20        30        40        50         

               70         80        90       100       110         
pF1KB3 LAAGCGQNPV-RQASVGAGIPYSVPAWSCQMICGSGLKAVCLAVQSIGIGDSSIVVAGGM
       : ..     . :.... .:::  .:: . . .::::....  . : : . .. .:. :: 
NP_006 LQSSSDAIYLARHVGLRVGIPKETPALTINRLCGSGFQSIVNGCQEICVKEAEVVLCGGT
      60        70        80        90       100       110         

     120       130         140       150       160       170       
pF1KB3 ENMSKAPHLAY-LRTGVKIG-EMPLTDSILCDGLTDAFHNCHMGITAENVAKKWQVSRED
       :.::.::. .  .: :.:.: .. : ::.  . :::   .  :..::::.: : ..:::.
NP_006 ESMSQAPYCVRNVRFGTKLGSDIKLEDSLWVS-LTDQHVQLPMAMTAENLAVKHKISREE
     120       130       140       150        160       170        

       180       190       200       210       220       230       
pF1KB3 QDKVAVLSQNRTENAQKAGHFDKEIVPVLVSTRRGLIEVKTDEFPRHGSNIEAMSKLKPY
        :: :. ::.: . :. ::.:. :..:. :.:..:   ...::  :  ...: ..:: : 
NP_006 CDKYALQSQQRWKAANDAGYFNDEMAPIEVKTKKGKQTMQVDEHARPQTTLEQLQKLPPV
      180       190       200       210       220       230        

       240       250       260       270       280       290       
pF1KB3 FLTDGTGTVTPANASGINDGAAAVVLMKKSEADKRGLTPLARIVSWSQVGVEPSIMGIGP
       :  :::  :: .::::. :::.::.. ... . :...:::::::..   : .::::::::
NP_006 FKKDGT--VTAGNASGVADGAGAVIIASEDAVKKHNFTPLARIVGYFVSGCDPSIMGIGP
      240         250       260       270       280       290      

       300       310       320       330       340       350       
pF1KB3 IPAIKQAVTKAGWSLEDVDIFEINEAFAAVSAAIVKELGLNPEKVNIEGGAIALGHPLGA
       .:::. :. ::: ::.:.:. :.:::::    :. . : :.  :.:..:::::::::::.
NP_006 VPAISGALKKAGLSLKDMDLVEVNEAFAPQYLAVERSLDLDISKTNVNGGAIALGHPLGG
        300       310       320       330       340       350      

       360       370       380       390        
pF1KB3 SGCRILVTLLHTLERMGRSRGVAALCIGGGMGIAMCVQRE 
       :: :: . :.: :.: : . .:.. :::::.:::. .:   
NP_006 SGSRITAHLVHELRRRGGKYAVGSACIGGGQGIAVIIQSTA
        360       370       380       390       

>>XP_006718898 (OMIM: 203750,607809) PREDICTED: acetyl-C  (337 aa)
 initn: 860 init1: 395 opt: 897  Z-score: 1151.0  bits: 221.6 E(85289): 2.3e-57
Smith-Waterman score: 897; 43.5% identity (73.8% similar) in 340 aa overlap (58-396:2-336)

        30        40        50        60        70        80       
pF1KB3 VPVQDLGSTVIKEVLKRATVAPEDVSEVIFGHVLAAGCGQNPVRQASVGAGIPYSVPAWS
                                     :.:: .: :: :.::: .:::.: :.:  .
XP_006                              MGNVLQGGEGQAPTRQAVLGAGLPISTPCTT
                                            10        20        30 

        90       100       110       120       130       140       
pF1KB3 CQMICGSGLKAVCLAVQSIGIGDSSIVVAGGMENMSKAPHLAYLRTGVKIGEMPLTDSIL
        . .:.::.::. .: ::.  : ....::::::.::..:..   : ..  : . : : :.
XP_006 INKVCASGMKAIMMASQSLMCGHQDVMVAGGMESMSNVPYVMN-RGSTPYGGVKLEDLIV
              40        50        60        70         80        90

       150       160       170       180       190       200       
pF1KB3 CDGLTDAFHNCHMGITAENVAKKWQVSREDQDKVAVLSQNRTENAQKAGHFDKEIVPVLV
        :::::.... :::  :::.::: ...:..::  :. : .:.. : .::.: .:..:: :
XP_006 KDGLTDVYNKIHMGSCAENTAKKLNIARNEQDAYAINSYTRSKAAWEAGKFGNEVIPVTV
              100       110       120       130       140       150

       210        220       230       240       250       260      
pF1KB3 STR-RGLIEVKTDEFPRHGSNIEAMSKLKPYFLTDGTGTVTPANASGINDGAAAVVLMKK
       ... .  . :: ::  ..  ..  . :::  :  .. :::: :::: .::::::.:::  
XP_006 TVKGQPDVVVKEDEEYKR-VDFSKVPKLKTVFQKEN-GTVTAANASTLNDGAAALVLMTA
              160        170       180        190       200        

        270       280       290       300       310       320      
pF1KB3 SEADKRGLTPLARIVSWSQVGVEPSIMGIGPIPAIKQAVTKAGWSLEDVDIFEINEAFAA
       . : . ..:::::::......:::  . :.:. : ....  .: . ::. ..:.::::. 
XP_006 DAAKRLNVTPLARIVAFADAAVEPIDFPIAPVYAASMVLKDVGLKKEDIAMWEVNEAFSL
      210       220       230       240       250       260        

        330       340       350       360       370       380      
pF1KB3 VSAAIVKELGLNPEKVNIEGGAIALGHPLGASGCRILVTLLHTLERMGRSRGVAALCIGG
       :  : .: : ..:.::::.:::..::::.: :: ::.  : :.: ..:.  :.:..: ::
XP_006 VVLANIKMLEIDPQKVNINGGAVSLGHPIGMSGARIVGHLTHAL-KQGE-YGLASICNGG
      270       280       290       300       310         320      

        390       
pF1KB3 GMGIAMCVQRE
       : . :: .:. 
XP_006 GGASAMLIQKL
        330       

>>XP_016873170 (OMIM: 203750,607809) PREDICTED: acetyl-C  (337 aa)
 initn: 860 init1: 395 opt: 897  Z-score: 1151.0  bits: 221.6 E(85289): 2.3e-57
Smith-Waterman score: 897; 43.5% identity (73.8% similar) in 340 aa overlap (58-396:2-336)

        30        40        50        60        70        80       
pF1KB3 VPVQDLGSTVIKEVLKRATVAPEDVSEVIFGHVLAAGCGQNPVRQASVGAGIPYSVPAWS
                                     :.:: .: :: :.::: .:::.: :.:  .
XP_016                              MGNVLQGGEGQAPTRQAVLGAGLPISTPCTT
                                            10        20        30 

        90       100       110       120       130       140       
pF1KB3 CQMICGSGLKAVCLAVQSIGIGDSSIVVAGGMENMSKAPHLAYLRTGVKIGEMPLTDSIL
        . .:.::.::. .: ::.  : ....::::::.::..:..   : ..  : . : : :.
XP_016 INKVCASGMKAIMMASQSLMCGHQDVMVAGGMESMSNVPYVMN-RGSTPYGGVKLEDLIV
              40        50        60        70         80        90

       150       160       170       180       190       200       
pF1KB3 CDGLTDAFHNCHMGITAENVAKKWQVSREDQDKVAVLSQNRTENAQKAGHFDKEIVPVLV
        :::::.... :::  :::.::: ...:..::  :. : .:.. : .::.: .:..:: :
XP_016 KDGLTDVYNKIHMGSCAENTAKKLNIARNEQDAYAINSYTRSKAAWEAGKFGNEVIPVTV
              100       110       120       130       140       150

       210        220       230       240       250       260      
pF1KB3 STR-RGLIEVKTDEFPRHGSNIEAMSKLKPYFLTDGTGTVTPANASGINDGAAAVVLMKK
       ... .  . :: ::  ..  ..  . :::  :  .. :::: :::: .::::::.:::  
XP_016 TVKGQPDVVVKEDEEYKR-VDFSKVPKLKTVFQKEN-GTVTAANASTLNDGAAALVLMTA
              160        170       180        190       200        

        270       280       290       300       310       320      
pF1KB3 SEADKRGLTPLARIVSWSQVGVEPSIMGIGPIPAIKQAVTKAGWSLEDVDIFEINEAFAA
       . : . ..:::::::......:::  . :.:. : ....  .: . ::. ..:.::::. 
XP_016 DAAKRLNVTPLARIVAFADAAVEPIDFPIAPVYAASMVLKDVGLKKEDIAMWEVNEAFSL
      210       220       230       240       250       260        

        330       340       350       360       370       380      
pF1KB3 VSAAIVKELGLNPEKVNIEGGAIALGHPLGASGCRILVTLLHTLERMGRSRGVAALCIGG
       :  : .: : ..:.::::.:::..::::.: :: ::.  : :.: ..:.  :.:..: ::
XP_016 VVLANIKMLEIDPQKVNINGGAVSLGHPIGMSGARIVGHLTHAL-KQGE-YGLASICNGG
      270       280       290       300       310         320      

        390       
pF1KB3 GMGIAMCVQRE
       : . :: .:. 
XP_016 GGASAMLIQKL
        330       

>>NP_001598 (OMIM: 604054) 3-ketoacyl-CoA thiolase, pero  (424 aa)
 initn: 817 init1: 414 opt: 841  Z-score: 1077.5  bits: 208.3 E(85289): 2.8e-53
Smith-Waterman score: 841; 41.6% identity (66.4% similar) in 399 aa overlap (3-391:33-416)

                                           10        20         30 
pF1KB3                             MNAGSDPVVIVSAARTIIGSFN-GALAAVPVQ
                                     :..  ::.: . :: :   . :..  .  .
NP_001 RLQVVLGHLRGPADSGWMPQAAPCLSGAPQASAADVVVVHGRRTAICRAGRGGFKDTTPD
             10        20        30        40        50        60  

              40        50        60        70        80        90 
pF1KB3 DLGSTVIKEVLKRATVAPEDVSEVIFGHVLAAGCGQNPVRQASVGAGIPYSVPAWSCQMI
       .: :.:.  ::: ... ::.....  :.::  : :   .: :.  . :: .::  . .  
NP_001 ELLSAVMTAVLKDVNLRPEQLGDICVGNVLQPGAGAIMARIAQFLSDIPETVPLSTVNRQ
             70        80        90       100       110       120  

             100       110       120       130       140       150 
pF1KB3 CGSGLKAVCLAVQSIGIGDSSIVVAGGMENMSKAPHLAYLRTGVKIGEMPLTDSILCDGL
       :.:::.::   . .:  :. .: .: :.:.:: : .          :.     : : .  
NP_001 CSSGLQAVASIAGGIRNGSYDIGMACGVESMSLADR----------GNPGNITSRLME--
            130       140       150                 160       170  

               160       170       180       190       200         
pF1KB3 TDAFHNC--HMGITAENVAKKWQVSREDQDKVAVLSQNRTENAQKAGHFDKEIVPVLVS-
        .  ..:   ::::.::::... .::: ::  :. ::...  ::. : :. ::::: .. 
NP_001 KEKARDCLIPMGITSENVAERFGISREKQDTFALASQQKAARAQSKGCFQAEIVPVTTTV
              180       190       200       210       220       230

           210       220       230       240       250       260   
pF1KB3 -----TRRGLIEVKTDEFPRHGSNIEAMSKLKPYFLTDGTGTVTPANASGINDGAAAVVL
            :.:. : :  ::  : ....:...:::: :  ::  ..: .:.: ..:::::..:
NP_001 HDDKGTKRS-ITVTQDEGIRPSTTMEGLAKLKPAFKKDG--STTAGNSSQVSDGAAAILL
               240       250       260         270       280       

           270       280       290       300       310       320   
pF1KB3 MKKSEADKRGLTPLARIVSWSQVGVEPSIMGIGPIPAIKQAVTKAGWSLEDVDIFEINEA
        ..:.:.. ::  :. . :.. ::: :.::::::  ::  :. ::: .. ::::::::::
NP_001 ARRSKAEELGLPILGVLRSYAVVGVPPDIMGIGPAYAIPVALQKAGLTVSDVDIFEINEA
       290       300       310       320       330       340       

           330       340       350       360       370        380  
pF1KB3 FAAVSAAIVKELGLNPEKVNIEGGAIALGHPLGASGCRILVTLLHTLERMG-RSRGVAAL
       ::. .:  :..: : :::::  :::.::::::: .: : ..:::. :.: : :. ::...
NP_001 FASQAAYCVEKLRLPPEKVNPLGGAVALGHPLGCTGARQVITLLNELKRRGKRAYGVVSM
       350       360       370       380       390       400       

            390         
pF1KB3 CIGGGMGIAMCVQRE  
       ::: ::: :        
NP_001 CIGTGMGAAAVFEYPGN
       410       420    

>>XP_016873171 (OMIM: 203750,607809) PREDICTED: acetyl-C  (301 aa)
 initn: 686 init1: 395 opt: 723  Z-score: 928.8  bits: 180.3 E(85289): 5.4e-45
Smith-Waterman score: 723; 43.2% identity (73.7% similar) in 285 aa overlap (113-396:21-300)

             90       100       110       120       130       140  
pF1KB3 VPAWSCQMICGSGLKAVCLAVQSIGIGDSSIVVAGGMENMSKAPHLAYLRTGVKIGEMPL
                                     ..::::::.::..:..   : ..  : . :
XP_016           MFYKEVKDKLLQGRQYWVQDVMVAGGMESMSNVPYVMN-RGSTPYGGVKL
                         10        20        30         40         

            150       160       170       180       190       200  
pF1KB3 TDSILCDGLTDAFHNCHMGITAENVAKKWQVSREDQDKVAVLSQNRTENAQKAGHFDKEI
        : :. :::::.... :::  :::.::: ...:..::  :. : .:.. : .::.: .:.
XP_016 EDLIVKDGLTDVYNKIHMGSCAENTAKKLNIARNEQDAYAINSYTRSKAAWEAGKFGNEV
      50        60        70        80        90       100         

            210        220       230       240       250       260 
pF1KB3 VPVLVSTR-RGLIEVKTDEFPRHGSNIEAMSKLKPYFLTDGTGTVTPANASGINDGAAAV
       .:: :... .  . :: ::  ..  ..  . :::  :  .. :::: :::: .::::::.
XP_016 IPVTVTVKGQPDVVVKEDEEYKR-VDFSKVPKLKTVFQKEN-GTVTAANASTLNDGAAAL
     110       120       130        140        150       160       

             270       280       290       300       310       320 
pF1KB3 VLMKKSEADKRGLTPLARIVSWSQVGVEPSIMGIGPIPAIKQAVTKAGWSLEDVDIFEIN
       :::  . : . ..:::::::......:::  . :.:. : ....  .: . ::. ..:.:
XP_016 VLMTADAAKRLNVTPLARIVAFADAAVEPIDFPIAPVYAASMVLKDVGLKKEDIAMWEVN
       170       180       190       200       210       220       

             330       340       350       360       370       380 
pF1KB3 EAFAAVSAAIVKELGLNPEKVNIEGGAIALGHPLGASGCRILVTLLHTLERMGRSRGVAA
       :::. :  : .: : ..:.::::.:::..::::.: :: ::.  : :.: ..:.  :.:.
XP_016 EAFSLVVLANIKMLEIDPQKVNINGGAVSLGHPIGMSGARIVGHLTHAL-KQGE-YGLAS
       230       240       250       260       270        280      

             390       
pF1KB3 LCIGGGMGIAMCVQRE
       .: ::: . :: .:. 
XP_016 ICNGGGGASAMLIQKL
         290       300 

>>XP_016873172 (OMIM: 203750,607809) PREDICTED: acetyl-C  (301 aa)
 initn: 686 init1: 395 opt: 723  Z-score: 928.8  bits: 180.3 E(85289): 5.4e-45
Smith-Waterman score: 723; 43.2% identity (73.7% similar) in 285 aa overlap (113-396:21-300)

             90       100       110       120       130       140  
pF1KB3 VPAWSCQMICGSGLKAVCLAVQSIGIGDSSIVVAGGMENMSKAPHLAYLRTGVKIGEMPL
                                     ..::::::.::..:..   : ..  : . :
XP_016           MFYKEVKDKLLQGRQYWVQDVMVAGGMESMSNVPYVMN-RGSTPYGGVKL
                         10        20        30         40         

            150       160       170       180       190       200  
pF1KB3 TDSILCDGLTDAFHNCHMGITAENVAKKWQVSREDQDKVAVLSQNRTENAQKAGHFDKEI
        : :. :::::.... :::  :::.::: ...:..::  :. : .:.. : .::.: .:.
XP_016 EDLIVKDGLTDVYNKIHMGSCAENTAKKLNIARNEQDAYAINSYTRSKAAWEAGKFGNEV
      50        60        70        80        90       100         

            210        220       230       240       250       260 
pF1KB3 VPVLVSTR-RGLIEVKTDEFPRHGSNIEAMSKLKPYFLTDGTGTVTPANASGINDGAAAV
       .:: :... .  . :: ::  ..  ..  . :::  :  .. :::: :::: .::::::.
XP_016 IPVTVTVKGQPDVVVKEDEEYKR-VDFSKVPKLKTVFQKEN-GTVTAANASTLNDGAAAL
     110       120       130        140        150       160       

             270       280       290       300       310       320 
pF1KB3 VLMKKSEADKRGLTPLARIVSWSQVGVEPSIMGIGPIPAIKQAVTKAGWSLEDVDIFEIN
       :::  . : . ..:::::::......:::  . :.:. : ....  .: . ::. ..:.:
XP_016 VLMTADAAKRLNVTPLARIVAFADAAVEPIDFPIAPVYAASMVLKDVGLKKEDIAMWEVN
       170       180       190       200       210       220       

             330       340       350       360       370       380 
pF1KB3 EAFAAVSAAIVKELGLNPEKVNIEGGAIALGHPLGASGCRILVTLLHTLERMGRSRGVAA
       :::. :  : .: : ..:.::::.:::..::::.: :: ::.  : :.: ..:.  :.:.
XP_016 EAFSLVVLANIKMLEIDPQKVNINGGAVSLGHPIGMSGARIVGHLTHAL-KQGE-YGLAS
       230       240       250       260       270        280      

             390       
pF1KB3 LCIGGGMGIAMCVQRE
       .: ::: . :: .:. 
XP_016 ICNGGGGASAMLIQKL
         290       300 

>>XP_006713186 (OMIM: 604054) PREDICTED: 3-ketoacyl-CoA   (272 aa)
 initn: 674 init1: 414 opt: 699  Z-score: 898.8  bits: 174.6 E(85289): 2.5e-43
Smith-Waterman score: 699; 50.2% identity (74.1% similar) in 239 aa overlap (160-391:29-264)

     130       140       150       160       170       180         
pF1KB3 YLRTGVKIGEMPLTDSILCDGLTDAFHNCHMGITAENVAKKWQVSREDQDKVAVLSQNRT
                                     ::::.::::... .::: ::  :. ::...
XP_006   MSLADRGNPGNITSRLMEKEKARDCLIPMGITSENVAERFGISREKQDTFALASQQKA
                 10        20        30        40        50        

     190       200             210       220       230       240   
pF1KB3 ENAQKAGHFDKEIVPVLVS------TRRGLIEVKTDEFPRHGSNIEAMSKLKPYFLTDGT
         ::. : :. ::::: ..      :.:. : :  ::  : ....:...:::: :  :: 
XP_006 ARAQSKGCFQAEIVPVTTTVHDDKGTKRS-ITVTQDEGIRPSTTMEGLAKLKPAFKKDG-
       60        70        80         90       100       110       

           250       260       270       280       290       300   
pF1KB3 GTVTPANASGINDGAAAVVLMKKSEADKRGLTPLARIVSWSQVGVEPSIMGIGPIPAIKQ
        ..: .:.: ..:::::..: ..:.:.. ::  :. . :.. ::: :.::::::  ::  
XP_006 -STTAGNSSQVSDGAAAILLARRSKAEELGLPILGVLRSYAVVGVPPDIMGIGPAYAIPV
         120       130       140       150       160       170     

           310       320       330       340       350       360   
pF1KB3 AVTKAGWSLEDVDIFEINEAFAAVSAAIVKELGLNPEKVNIEGGAIALGHPLGASGCRIL
       :. ::: .. ::::::::::::. .:  :..: : :::::  :::.::::::: .: : .
XP_006 ALQKAGLTVSDVDIFEINEAFASQAAYCVEKLRLPPEKVNPLGGAVALGHPLGCTGARQV
         180       190       200       210       220       230     

           370        380       390         
pF1KB3 VTLLHTLERMG-RSRGVAALCIGGGMGIAMCVQRE  
       .:::. :.: : :. ::...::: ::: :        
XP_006 ITLLNELKRRGKRAYGVVSMCIGTGMGAAAVFEYPGN
         240       250       260       270  




397 residues in 1 query   sequences
60827320 residues in 85289 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Thu Nov  3 13:25:02 2016 done: Thu Nov  3 13:25:03 2016
 Total Scan time:  7.700 Total Display time:  0.050

Function used was FASTA [36.3.4 Apr, 2011]
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