Result of FASTA (ccds) for pF1KB3465
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KB3465, 345 aa
  1>>>pF1KB3465 345 - 345 aa - 345 aa
Library: human.CCDS.faa
  18511270 residues in 32554 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 12.6023+/-0.00107; mu= -17.0451+/- 0.063
 mean_var=424.8386+/-95.198, 0's: 0 Z-trim(115.5): 619  B-trim: 911 in 1/50
 Lambda= 0.062225
 statistics sampled from 15286 (16060) to 15286 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.801), E-opt: 0.2 (0.493), width:  16
 Scan time:  3.310

The best scores are:                                      opt bits E(32554)
CCDS3444.1 KLF3 gene_id:51274|Hs108|chr4           ( 345) 2404 229.4 3.3e-60
CCDS9449.1 KLF12 gene_id:11278|Hs108|chr13         ( 402)  668 73.6 3.1e-13
CCDS14373.1 KLF8 gene_id:11279|Hs108|chrX          ( 359)  665 73.3 3.4e-13
CCDS66562.1 KLF5 gene_id:688|Hs108|chr13           ( 366)  624 69.7 4.4e-12
CCDS9448.1 KLF5 gene_id:688|Hs108|chr13            ( 457)  624 69.7 5.2e-12
CCDS7060.1 KLF6 gene_id:1316|Hs108|chr10           ( 283)  576 65.3 7.1e-11
CCDS6770.2 KLF4 gene_id:9314|Hs108|chr9            ( 479)  582 66.0 7.4e-11


>>CCDS3444.1 KLF3 gene_id:51274|Hs108|chr4                (345 aa)
 initn: 2404 init1: 2404 opt: 2404  Z-score: 1194.4  bits: 229.4 E(32554): 3.3e-60
Smith-Waterman score: 2404; 100.0% identity (100.0% similar) in 345 aa overlap (1-345:1-345)

               10        20        30        40        50        60
pF1KB3 MLMFDPVPVKQEAMDPVSVSYPSNYMESMKPNKYGVIYSTPLPEKFFQTPEGLSHGIQME
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS34 MLMFDPVPVKQEAMDPVSVSYPSNYMESMKPNKYGVIYSTPLPEKFFQTPEGLSHGIQME
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB3 PVDLTVNKRSSPPSAGNSPSSLKFPSSHRRASPGLSMPSSSPPIKKYSPPSPGVQPFGVP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS34 PVDLTVNKRSSPPSAGNSPSSLKFPSSHRRASPGLSMPSSSPPIKKYSPPSPGVQPFGVP
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB3 LSMPPVMAAALSRHGIRSPGILPVIQPVVVQPVPFMYTSHLQQPLMVSLSEEMENSSSSM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS34 LSMPPVMAAALSRHGIRSPGILPVIQPVVVQPVPFMYTSHLQQPLMVSLSEEMENSSSSM
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB3 QVPVIESYEKPISQKKIKIEPGIEPQRTDYYPEEMSPPLMNSVSPPQALLQENHPSVIVQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS34 QVPVIESYEKPISQKKIKIEPGIEPQRTDYYPEEMSPPLMNSVSPPQALLQENHPSVIVQ
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB3 PGKRPLPVESPDTQRKRRIHRCDYDGCNKVYTKSSHLKAHRRTHTGEKPYKCTWEGCTWK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS34 PGKRPLPVESPDTQRKRRIHRCDYDGCNKVYTKSSHLKAHRRTHTGEKPYKCTWEGCTWK
              250       260       270       280       290       300

              310       320       330       340     
pF1KB3 FARSDELTRHFRKHTGIKPFQCPDCDRSFSRSDHLALHRKRHMLV
       :::::::::::::::::::::::::::::::::::::::::::::
CCDS34 FARSDELTRHFRKHTGIKPFQCPDCDRSFSRSDHLALHRKRHMLV
              310       320       330       340     

>>CCDS9449.1 KLF12 gene_id:11278|Hs108|chr13              (402 aa)
 initn: 786 init1: 645 opt: 668  Z-score: 351.2  bits: 73.6 E(32554): 3.1e-13
Smith-Waterman score: 779; 40.8% identity (63.6% similar) in 385 aa overlap (9-345:36-402)

                                     10        20        30        
pF1KB3                       MLMFDPVPVKQEAMDPVSVSYPSNYMESMKPNKYGVIY
                                     ...:  .:   .::.  ::.. :   . . 
CCDS94 KRKTIKNINTFENRMLMLDGMPAVRVKTELLESEQGSPNVHNYPD--MEAV-PLLLNNVK
          10        20        30        40        50           60  

       40        50        60         70        80            90   
pF1KB3 STPLPEKFFQTPEGLSHGIQMEPVDLTVNK-RSSPPSAGNSPSSL----KFPSSHRRASP
       . : ::  ... .      : :::::..:: :.:: ....:: :.    . :::   .: 
CCDS94 GEP-PEDSLSVDH---FQTQTEPVDLSINKARTSPTAVSSSPVSMTASASSPSSTSTSSS
              70           80        90       100       110        

           100        110       120       130       140        150 
pF1KB3 GLSMPSSSPP-IKKYSPPSPGVQPFGVPLSMPPVMAAALSRHGIRSPGILPVIQPVV-VQ
       . :  .:::  : . :  : .    .. :.  :..:.:    :. .  .: .:.::   .
CCDS94 SSSRLASSPTVITSVSSASSS----STVLTPGPLVASA---SGVGGQQFLHIIHPVPPSS
      120       130           140       150          160       170 

               160               170       180       190       200 
pF1KB3 PVPFMYT--SHLQQ--------PLMVSLSEEMENSSSSMQVPVIESYEKPISQKKIKIEP
       :. .. .  ::...        :.. .  .   : .... ::..:. .   .. : ...:
CCDS94 PMNLQSNKLSHVHRIPVVVQSVPVVYTAVRSPGNVNNTIVVPLLEDGR---GHGKAQMDP
             180       190       200       210          220        

                210       220              230       240           
pF1KB3 -GIEPQ--RTDYYPEEMSPPLMNSVSPP--QAL-----LQENHPSVIVQP-GKR------
        :. :.  ..:   ...    ..::.     ::     .:: ::: . .  :.:      
CCDS94 RGLSPRQSKSDSDDDDLPNVTLDSVNETGSTALSIARAVQEVHPSPVSRVRGNRMNNQKF
      230       240       250       260       270       280        

               250                260       270       280       290
pF1KB3 -----PLPVES---------PDTQRKRRIHRCDYDGCNKVYTKSSHLKAHRRTHTGEKPY
            :. .::         ::. :::::::::..:::::::::::::::::::::::::
CCDS94 PCSISPFSIESTRRQRRSESPDS-RKRRIHRCDFEGCNKVYTKSSHLKAHRRTHTGEKPY
      290       300       310        320       330       340       

              300       310       320       330       340     
pF1KB3 KCTWEGCTWKFARSDELTRHFRKHTGIKPFQCPDCDRSFSRSDHLALHRKRHMLV
       ::::::::::::::::::::.:::::.:::.: ::::::::::::::::.:::::
CCDS94 KCTWEGCTWKFARSDELTRHYRKHTGVKPFKCADCDRSFSRSDHLALHRRRHMLV
       350       360       370       380       390       400  

>>CCDS14373.1 KLF8 gene_id:11279|Hs108|chrX               (359 aa)
 initn: 692 init1: 586 opt: 665  Z-score: 350.4  bits: 73.3 E(32554): 3.4e-13
Smith-Waterman score: 696; 38.9% identity (59.5% similar) in 368 aa overlap (1-342:22-356)

                                    10        20                30 
pF1KB3                      MLMFDPVPVKQEAMDPVSVSYPSNYMESM--------KP
                            : .:  : .. .  ::  . : ::.            .:
CCDS14 MVDMDKLINNLEVQLNSEGGSMQVFKQVTASVRNRDPPEIEYRSNMTSPTLLDANPMENP
               10        20        30        40        50        60

              40        50        60        70                     
pF1KB3 NKYGVIYSTPLPEKFFQTPEGLSHGIQMEPVDLTVNKRSSP-------------PSAGNS
         .. :   : ::... .  .:    :.:::::. .: ..:             :.  .:
CCDS14 ALFNDIKIEP-PEELLASDFSLP---QVEPVDLSFHKPKAPLQPASMLQAPIRPPKPQSS
               70         80           90       100       110      

       80        90       100        110        120       130      
pF1KB3 PSSLKFPSSHRRASPGLSMPSS-SPPIKKYSPPSPGVQP-FGVPLSMPPVMAAALSRHGI
       :..:   .:    : . ..:.  .:     :  : : :  . :  ..: :     .. : 
CCDS14 PQTLVVSTSTSDMSTSANIPTVLTPGSVLTSSQSTGSQQILHVIHTIPSVSLP--NKMG-
        120       130       140       150       160         170    

        140       150       160       170       180       190      
pF1KB3 RSPGILPVIQPVVVQPVPFMYTSHLQQPLMVSLSEEMENSSSSMQVPVIESYEKPISQKK
          :.  .  ::::: .:..::.    :         ... ... ::.: .  :  .  .
CCDS14 ---GLKTI--PVVVQSLPMVYTT---LP--------ADGGPAAITVPLIGGDGK--NAGS
                180       190                  200       210       

        200        210       220        230       240        250   
pF1KB3 IKIEP-GIEPQRTDYYPEEMSPPLMNS-VSPPQALLQENHPSVIVQ-PGKRPLPVESPDT
       .:..: .. : .     :: .    .: ..  :.: ::  :....:  :.     :: : 
CCDS14 VKVDPTSMSPLEIPSDSEESTIESGSSALQSLQGLQQE--PAAMAQMQGE-----ESLDL
         220       230       240       250         260             

           260       270       280       290       300       310   
pF1KB3 QRKRRIHRCDYDGCNKVYTKSSHLKAHRRTHTGEKPYKCTWEGCTWKFARSDELTRHFRK
       .: ::::.::. ::.:::::::::::::: :::::::::::.::.:::::::::::::::
CCDS14 KR-RRIHQCDFAGCSKVYTKSSHLKAHRRIHTGEKPYKCTWDGCSWKFARSDELTRHFRK
      270        280       290       300       310       320       

           320       330       340     
pF1KB3 HTGIKPFQCPDCDRSFSRSDHLALHRKRHMLV
       :::::::.: ::.:::::::::.:::.::   
CCDS14 HTGIKPFRCTDCNRSFSRSDHLSLHRRRHDTM
       330       340       350         

>>CCDS66562.1 KLF5 gene_id:688|Hs108|chr13                (366 aa)
 initn: 615 init1: 563 opt: 624  Z-score: 330.4  bits: 69.7 E(32554): 4.4e-12
Smith-Waterman score: 641; 35.3% identity (60.3% similar) in 368 aa overlap (6-342:11-364)

                      10        20        30        40             
pF1KB3      MLMFDPVPV--KQEAMDPVSVSYPSNYMESMKPNKYGVIYSTPLPE------KFF
                 :::.  ... .   :.:  .... . .   :.. ... ::.       ..
CCDS66 MEKYLTPQLPPVPIIPEHKKYRRDSASVVDQFFTDTEGLPYSINMNVFLPDITHLRTGLY
               10        20        30        40        50        60

        50        60          70          80        90             
pF1KB3 QTPEGLSHGIQMEPVDLTVNKR--SSPPSAGNS--PSSLKFPSSHRRASPGLS-------
       .. .     :. ::: .  ..   ..:: : ..  :   .. :::. :.: ..       
CCDS66 KSQRPCVTHIKTEPVAIFSHQSETTAPPPAPTQALPEFTSIFSSHQTAAPEVNNIFIKQE
               70        80        90       100       110       120

        100       110         120          130       140       150 
pF1KB3 MPSSSPPIKKYSPPSPG--VQPFGVP-LSMPPV--MAAALSRHGIRSPGILPVIQPVVVQ
       .:.  : ..   : . :   : ...: :.::    ..::..  ..   . .  .. . ..
CCDS66 LPT--PDLHLSVPTQQGHLYQLLNTPDLDMPSSTNQTAAMDTLNVSMSAAMAGLN-THTS
                130       140       150       160       170        

             160       170       180       190       200       210 
pF1KB3 PVPFMYTSHLQQPLMVSLSEEMENSSSSMQVPVIESYEKPISQKKIKIEPGIEPQRTDYY
        ::   ....:   :   .  :     :. .:   .:  :   ..   :::  :.:   .
CCDS66 AVPQTAVKQFQG--MPPCTYTMP----SQFLPQQATYFPPSPPSS---EPG-SPDRQAEM
       180         190           200       210           220       

               220       230       240            250       260    
pF1KB3 PEEMSPP--LMNSVSPPQALLQENHPSVIVQPGKRPLPVE-----SPDTQRKRRIHRCDY
        ....::     ...   :. . : :...   ..   ::.     .:: . ::::: :::
CCDS66 LQNLTPPPSYAATIASKLAIHNPNLPTTLPVNSQNIQPVRYNRRSNPDLE-KRRIHYCDY
       230       240       250       260       270        280      

          270       280       290       300       310       320    
pF1KB3 DGCNKVYTKSSHLKAHRRTHTGEKPYKCTWEGCTWKFARSDELTRHFRKHTGIKPFQCPD
        ::.:::::::::::: :::::::::::::::: :.::::::::::.::::: :::::  
CCDS66 PGCTKVYTKSSHLKAHLRTHTGEKPYKCTWEGCDWRFARSDELTRHYRKHTGAKPFQCGV
        290       300       310       320       330       340      

          330       340     
pF1KB3 CDRSFSRSDHLALHRKRHMLV
       :.:::::::::::: :::   
CCDS66 CNRSFSRSDHLALHMKRHQN 
        350       360       

>>CCDS9448.1 KLF5 gene_id:688|Hs108|chr13                 (457 aa)
 initn: 615 init1: 563 opt: 624  Z-score: 329.1  bits: 69.7 E(32554): 5.2e-12
Smith-Waterman score: 641; 35.3% identity (60.3% similar) in 368 aa overlap (6-342:102-455)

                                          10        20        30   
pF1KB3                          MLMFDPVPV--KQEAMDPVSVSYPSNYMESMKPNK
                                     :::.  ... .   :.:  .... . .   
CCDS94 QPPATGPRLPPEDLVQTRCEMEKYLTPQLPPVPIIPEHKKYRRDSASVVDQFFTDTEGLP
              80        90       100       110       120       130 

            40              50        60          70          80   
pF1KB3 YGVIYSTPLPE------KFFQTPEGLSHGIQMEPVDLTVNKR--SSPPSAGNS--PSSLK
       :.. ... ::.       .... .     :. ::: .  ..   ..:: : ..  :   .
CCDS94 YSINMNVFLPDITHLRTGLYKSQRPCVTHIKTEPVAIFSHQSETTAPPPAPTQALPEFTS
             140       150       160       170       180       190 

            90              100       110         120          130 
pF1KB3 FPSSHRRASPGLS-------MPSSSPPIKKYSPPSPG--VQPFGVP-LSMPPV--MAAAL
       . :::. :.: ..       .:.  : ..   : . :   : ...: :.::    ..::.
CCDS94 IFSSHQTAAPEVNNIFIKQELPT--PDLHLSVPTQQGHLYQLLNTPDLDMPSSTNQTAAM
             200       210         220       230       240         

             140       150       160       170       180       190 
pF1KB3 SRHGIRSPGILPVIQPVVVQPVPFMYTSHLQQPLMVSLSEEMENSSSSMQVPVIESYEKP
       .  ..   . .  .. . .. ::   ....:   :   .  :     :. .:   .:  :
CCDS94 DTLNVSMSAAMAGLN-THTSAVPQTAVKQFQG--MPPCTYTMP----SQFLPQQATYFPP
     250       260        270       280             290       300  

             200       210         220       230       240         
pF1KB3 ISQKKIKIEPGIEPQRTDYYPEEMSPP--LMNSVSPPQALLQENHPSVIVQPGKRPLPVE
          ..   :::  :.:   . ....::     ...   :. . : :...   ..   ::.
CCDS94 SPPSS---EPG-SPDRQAEMLQNLTPPPSYAATIASKLAIHNPNLPTTLPVNSQNIQPVR
               310        320       330       340       350        

          250       260       270       280       290       300    
pF1KB3 -----SPDTQRKRRIHRCDYDGCNKVYTKSSHLKAHRRTHTGEKPYKCTWEGCTWKFARS
            .:: . ::::: ::: ::.:::::::::::: :::::::::::::::: :.::::
CCDS94 YNRRSNPDLE-KRRIHYCDYPGCTKVYTKSSHLKAHLRTHTGEKPYKCTWEGCDWRFARS
      360        370       380       390       400       410       

          310       320       330       340     
pF1KB3 DELTRHFRKHTGIKPFQCPDCDRSFSRSDHLALHRKRHMLV
       ::::::.::::: :::::  :.:::::::::::: :::   
CCDS94 DELTRHYRKHTGAKPFQCGVCNRSFSRSDHLALHMKRHQN 
       420       430       440       450        

>>CCDS7060.1 KLF6 gene_id:1316|Hs108|chr10                (283 aa)
 initn: 747 init1: 557 opt: 576  Z-score: 308.7  bits: 65.3 E(32554): 7.1e-11
Smith-Waterman score: 576; 72.1% identity (83.7% similar) in 104 aa overlap (240-343:182-283)

     210       220       230       240       250       260         
pF1KB3 YYPEEMSPPLMNSVSPPQALLQENHPSVIVQPGKRPLPVESPDTQRKRRIHRCDYDGCNK
                                     .:: .     :::   .::.::: ..:: :
CCDS70 PELSREPSQLWGCVPGELPSPGKVRSGTSGKPGDKGNGDASPDG--RRRVHRCHFNGCRK
             160       170       180       190         200         

     270       280       290       300       310       320         
pF1KB3 VYTKSSHLKAHRRTHTGEKPYKCTWEGCTWKFARSDELTRHFRKHTGIKPFQCPDCDRSF
       :::::::::::.:::::::::.:.:::: :.:::::::::::::::: :::.:  ::: :
CCDS70 VYTKSSHLKAHQRTHTGEKPYRCSWEGCEWRFARSDELTRHFRKHTGAKPFKCSHCDRCF
     210       220       230       240       250       260         

     330       340     
pF1KB3 SRSDHLALHRKRHMLV
       ::::::::: :::.  
CCDS70 SRSDHLALHMKRHL  
     270       280     

>>CCDS6770.2 KLF4 gene_id:9314|Hs108|chr9                 (479 aa)
 initn: 547 init1: 525 opt: 582  Z-score: 308.4  bits: 66.0 E(32554): 7.4e-11
Smith-Waterman score: 591; 39.0% identity (59.0% similar) in 290 aa overlap (58-342:207-478)

        30        40        50        60        70        80       
pF1KB3 SMKPNKYGVIYSTPLPEKFFQTPEGLSHGIQMEPVDLTVNKRSSPPSAGNSPSSLKFPSS
                                     ...:: .   .. .::..:      ::  .
CCDS67 SAPPPTAPFNLADINDVSPSGGFVAELLRPELDPVYIP-PQQPQPPGGGLMG---KFVLK
        180       190       200       210        220          230  

        90       100       110         120        130       140    
pF1KB3 HRRASPGLSMPSSSPPIKKYSPPSP-GVQPFGV-PLSM-PPVMAAALSRHGIRSPGILPV
          ..::  .  .:: . . :  :: : .:  : : .  ::     ...... :   : .
CCDS67 ASLSAPGSEY--GSPSVISVSKGSPDGSHPVVVAPYNGGPPRTCPKIKQEAVSSCTHLGA
            240         250       260       270       280       290

          150       160       170       180       190       200    
pF1KB3 IQPVVVQPVPFMYTSHLQQPLMVSLSEEMENSSSSMQVPVIESYEKPISQKKIKIEPGIE
         :.     :   ..: . ::  .:      : ..  . . :   .   .  . . ::..
CCDS67 GPPLSNGHRP---AAH-DFPLGRQLP-----SRTTPTLGLEEVLSSRDCHPALPLPPGFH
              300           310            320       330       340 

          210       220       230       240       250         260  
pF1KB3 PQRTDYYPEEMSPPLMNSVSPPQALLQENHPSVIVQPGKRPLPVESPDTQRKRRI--HRC
       :.    ::  . :  :.   ::    ::  :    .: ..: : ..  .  ..:   : :
CCDS67 PHPGPNYPSFL-PDQMQPQVPPLHY-QELMPPGSCMP-EEPKPKRGRRSWPRKRTATHTC
             350        360        370        380       390        

            270       280       290       300       310       320  
pF1KB3 DYDGCNKVYTKSSHLKAHRRTHTGEKPYKCTWEGCTWKFARSDELTRHFRKHTGIKPFQC
       :: ::.:.:::::::::: :::::::::.: :.:: ::::::::::::.::::: .::::
CCDS67 DYAGCGKTYTKSSHLKAHLRTHTGEKPYHCDWDGCGWKFARSDELTRHYRKHTGHRPFQC
      400       410       420       430       440       450        

            330       340     
pF1KB3 PDCDRSFSRSDHLALHRKRHMLV
         :::.:::::::::: :::   
CCDS67 QKCDRAFSRSDHLALHMKRHF  
      460       470           




345 residues in 1 query   sequences
18511270 residues in 32554 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Thu Nov  3 13:19:20 2016 done: Thu Nov  3 13:19:21 2016
 Total Scan time:  3.310 Total Display time:  0.010

Function used was FASTA [36.3.4 Apr, 2011]
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