Result of FASTA (omim) for pF1KB3404
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KB3404, 1691 aa
  1>>>pF1KB3404 1691 - 1691 aa - 1691 aa
Library: /omim/omim.rfq.tfa
  60827320 residues in 85289 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 15.7018+/-0.000745; mu= -22.1247+/- 0.046
 mean_var=1123.6833+/-236.034, 0's: 0 Z-trim(117.6): 1185  B-trim: 0 in 0/61
 Lambda= 0.038261
 statistics sampled from 28429 (29694) to 28429 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.658), E-opt: 0.2 (0.348), width:  16
 Scan time: 17.950

The best scores are:                                      opt bits E(85289)
XP_005273381 (OMIM: 603412) PREDICTED: serine/thre (1732) 6296 366.1 1.5e-99
XP_016858067 (OMIM: 603412) PREDICTED: serine/thre (1767) 6296 366.1 1.5e-99
XP_005273377 (OMIM: 603412) PREDICTED: serine/thre (1794) 6296 366.1 1.6e-99
XP_005273375 (OMIM: 603412) PREDICTED: serine/thre (1829) 6296 366.2 1.6e-99
XP_016858071 (OMIM: 603412) PREDICTED: serine/thre (1589) 6289 365.7 1.9e-99
NP_003598 (OMIM: 603412) serine/threonine-protein  (1719) 6289 365.7   2e-99
XP_005273379 (OMIM: 603412) PREDICTED: serine/thre (1754) 6289 365.7   2e-99
XP_005273378 (OMIM: 603412) PREDICTED: serine/thre (1781) 6289 365.8   2e-99
XP_011542610 (OMIM: 603412) PREDICTED: serine/thre (1783) 6289 365.8   2e-99
XP_006711898 (OMIM: 603412) PREDICTED: serine/thre (1797) 6289 365.8   2e-99
XP_011542609 (OMIM: 603412) PREDICTED: serine/thre (1810) 6289 365.8   2e-99
XP_006711897 (OMIM: 603412) PREDICTED: serine/thre (1816) 6289 365.8 2.1e-99
XP_005273374 (OMIM: 603412) PREDICTED: serine/thre (1832) 6289 365.8 2.1e-99
XP_011542608 (OMIM: 603412) PREDICTED: serine/thre (1845) 6289 365.8 2.1e-99
XP_016858070 (OMIM: 603412) PREDICTED: serine/thre (1712) 5602 327.8 5.2e-88
XP_016858068 (OMIM: 603412) PREDICTED: serine/thre (1741) 5602 327.8 5.2e-88
XP_016858069 (OMIM: 603412) PREDICTED: serine/thre (1741) 5602 327.8 5.2e-88
NP_055641 (OMIM: 603412) serine/threonine-protein  (1638) 5004 294.8 4.3e-78
XP_011535689 (OMIM: 614062) PREDICTED: serine/thre (1460) 4383 260.4 8.4e-68
XP_005268287 (OMIM: 614062) PREDICTED: serine/thre (1490) 4383 260.4 8.5e-68
XP_005268286 (OMIM: 614062) PREDICTED: serine/thre (1685) 4383 260.5 9.2e-68
XP_005268285 (OMIM: 614062) PREDICTED: serine/thre (1702) 4383 260.5 9.2e-68
NP_006026 (OMIM: 614062) serine/threonine-protein  (1711) 4383 260.5 9.3e-68
XP_005268284 (OMIM: 614062) PREDICTED: serine/thre (1728) 4383 260.5 9.3e-68
XP_011542611 (OMIM: 603412) PREDICTED: serine/thre (1764) 4135 246.9 1.2e-63
XP_016873487 (OMIM: 613991) PREDICTED: serine/thre (1081) 2148 136.9 9.7e-31
XP_011543463 (OMIM: 613991) PREDICTED: serine/thre (1135) 2148 136.9 9.9e-31
XP_016873486 (OMIM: 613991) PREDICTED: serine/thre (1139) 2148 136.9   1e-30
XP_011543461 (OMIM: 613991) PREDICTED: serine/thre (1481) 2148 137.1 1.2e-30
XP_011543460 (OMIM: 613991) PREDICTED: serine/thre (1495) 2148 137.1 1.2e-30
XP_011543459 (OMIM: 613991) PREDICTED: serine/thre (1530) 2148 137.1 1.2e-30
NP_059995 (OMIM: 613991) serine/threonine-protein  (1551) 2148 137.1 1.2e-30
XP_011543457 (OMIM: 613991) PREDICTED: serine/thre (1569) 2148 137.1 1.2e-30
XP_016873485 (OMIM: 613991) PREDICTED: serine/thre (1568) 2146 137.0 1.3e-30
XP_011543458 (OMIM: 613991) PREDICTED: serine/thre (1562) 2134 136.3 2.1e-30
XP_016873488 (OMIM: 613991) PREDICTED: serine/thre ( 865) 1957 126.2 1.3e-27
XP_011543462 (OMIM: 613991) PREDICTED: serine/thre (1471) 1798 117.7 7.6e-25
NP_004400 (OMIM: 160900,605377) myotonin-protein k ( 629) 1726 113.3 7.2e-24
NP_001275695 (OMIM: 160900,605377) myotonin-protei ( 530) 1712 112.4 1.1e-23
NP_001075029 (OMIM: 160900,605377) myotonin-protei ( 624) 1712 112.5 1.2e-23
NP_001075031 (OMIM: 160900,605377) myotonin-protei ( 625) 1712 112.5 1.2e-23
NP_001075032 (OMIM: 160900,605377) myotonin-protei ( 639) 1594 106.0 1.1e-21
NP_001275693 (OMIM: 160900,605377) myotonin-protei ( 655) 1594 106.0 1.1e-21
NP_005397 (OMIM: 601702) rho-associated protein ki (1354) 1528 102.8 2.2e-20
NP_004841 (OMIM: 604002) rho-associated protein ki (1388) 1519 102.3 3.2e-20
XP_016860867 (OMIM: 604002) PREDICTED: rho-associa (1404) 1519 102.3 3.2e-20
XP_005246247 (OMIM: 604002) PREDICTED: rho-associa (1417) 1519 102.3 3.2e-20
NP_001275694 (OMIM: 160900,605377) myotonin-protei ( 541) 1429 96.8 5.6e-19
NP_001308572 (OMIM: 604002) rho-associated protein (1302) 1425 97.1 1.1e-18
XP_011508719 (OMIM: 604002) PREDICTED: rho-associa (1331) 1425 97.1 1.1e-18


>>XP_005273381 (OMIM: 603412) PREDICTED: serine/threonin  (1732 aa)
 initn: 6296 init1: 6296 opt: 6296  Z-score: 1908.1  bits: 366.1 E(85289): 1.5e-99
Smith-Waterman score: 10995; 97.6% identity (97.6% similar) in 1723 aa overlap (1-1682:1-1723)

               10        20        30        40        50        60
pF1KB3 MSGEVRLRQLEQFILDGPAQTNGQCFSVETLLDILICLYDECNNSPLRREKNILEYLEWA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MSGEVRLRQLEQFILDGPAQTNGQCFSVETLLDILICLYDECNNSPLRREKNILEYLEWA
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB3 KPFTSKVKQMRLHREDFEILKVIGRGAFGEVAVVKLKNADKVFAMKILNKWEMLKRAETA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 KPFTSKVKQMRLHREDFEILKVIGRGAFGEVAVVKLKNADKVFAMKILNKWEMLKRAETA
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB3 CFREERDVLVNGDNKWITTLHYAFQDDNNLYLVMDYYVGGDLLTLLSKFEDRLPEDMARF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 CFREERDVLVNGDNKWITTLHYAFQDDNNLYLVMDYYVGGDLLTLLSKFEDRLPEDMARF
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB3 YLAEMVIAIDSVHQLHYVHRDIKPDNILMDMNGHIRLADFGSCLKLMEDGTVQSSVAVGT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 YLAEMVIAIDSVHQLHYVHRDIKPDNILMDMNGHIRLADFGSCLKLMEDGTVQSSVAVGT
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB3 PDYISPEILQAMEDGKGRYGPECDWWSLGVCMYEMLYGETPFYAESLVETYGKIMNHKER
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 PDYISPEILQAMEDGKGRYGPECDWWSLGVCMYEMLYGETPFYAESLVETYGKIMNHKER
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KB3 FQFPAQVTDVSENAKDLIRRLICSREHRLGQNGIEDFKKHPFFSGIDWDNIRNCEAPYIP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 FQFPAQVTDVSENAKDLIRRLICSREHRLGQNGIEDFKKHPFFSGIDWDNIRNCEAPYIP
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KB3 EVSSPTDTSNFDVDDDCLKNSETMPPPTHTAFSGHHLPFVGFTYTSSCVLSDRSCLRVTA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 EVSSPTDTSNFDVDDDCLKNSETMPPPTHTAFSGHHLPFVGFTYTSSCVLSDRSCLRVTA
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KB3 GPTSLDLDVNVQRTLDNNLATEAYERRIKRLEQEKLELSRKLQESTQTVQALQYSTVDGP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 GPTSLDLDVNVQRTLDNNLATEAYERRIKRLEQEKLELSRKLQESTQTVQALQYSTVDGP
              430       440       450       460       470       480

              490       500       510       520       530       540
pF1KB3 LTASKDLEIKNLKEEIEKLRKQVTESSHLEQQLEEANAVRQELDDAFRQIKAYEKQIKTL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LTASKDLEIKNLKEEIEKLRKQVTESSHLEQQLEEANAVRQELDDAFRQIKAYEKQIKTL
              490       500       510       520       530       540

              550       560       570       580       590       600
pF1KB3 QQEREDLNKELVQASERLKNQSKELKDAHCQRKLAMQEFMEINERLTELHTQKQKLARHV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 QQEREDLNKELVQASERLKNQSKELKDAHCQRKLAMQEFMEINERLTELHTQKQKLARHV
              550       560       570       580       590       600

              610       620       630       640       650       660
pF1KB3 RDKEEEVDLVMQKVESLRQELRRTERAKKELEVHTEALAAEASKDRKLREQSEHYSKQLE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 RDKEEEVDLVMQKVESLRQELRRTERAKKELEVHTEALAAEASKDRKLREQSEHYSKQLE
              610       620       630       640       650       660

              670       680       690       700       710       720
pF1KB3 NELEGLKQKQISYSPGVCSIEHQQEITKLKTDLEKKSIFYEEELSKREGIHANEIKNLKK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 NELEGLKQKQISYSPGVCSIEHQQEITKLKTDLEKKSIFYEEELSKREGIHANEIKNLKK
              670       680       690       700       710       720

              730       740       750       760       770       780
pF1KB3 ELHDSEGQQLALNKEIMILKDKLEKTRRESQSEREEFESEFKQQYEREKVLLTEENKKLT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 ELHDSEGQQLALNKEIMILKDKLEKTRRESQSEREEFESEFKQQYEREKVLLTEENKKLT
              730       740       750       760       770       780

              790       800       810       820       830       840
pF1KB3 SELDKLTTLYENLSIHNQQLEEEVKDLADKKESVAHWEAQITEIIQWVSDEKDARGYLQA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SELDKLTTLYENLSIHNQQLEEEVKDLADKKESVAHWEAQITEIIQWVSDEKDARGYLQA
              790       800       810       820       830       840

              850       860       870       880       890       900
pF1KB3 LASKMTEELEALRNSSLGTRATDMPWKMRRFAKLDMSARLELQSALDAEIRAKQAIQEEL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LASKMTEELEALRNSSLGTRATDMPWKMRRFAKLDMSARLELQSALDAEIRAKQAIQEEL
              850       860       870       880       890       900

              910       920       930       940       950       960
pF1KB3 NKVKASNIITECKLKDSEKKNLELLSEIEQLIKDTEELRSEKGIEHQDSQHSFLAFLNTP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 NKVKASNIITECKLKDSEKKNLELLSEIEQLIKDTEELRSEKGIEHQDSQHSFLAFLNTP
              910       920       930       940       950       960

                                                       970         
pF1KB3 TDALDQFER-----------------------------------------KTHQFFVKSF
       :::::::::                                         ::::::::::
XP_005 TDALDQFERSPSCTPASKGRRTVDSTPLSVHTPTLRKKGCPGSTGFPPKRKTHQFFVKSF
              970       980       990      1000      1010      1020

     980       990      1000      1010      1020      1030         
pF1KB3 TTPTKCHQCTSLMVGLIRQGCSCEVCGFSCHITCVNKAPTTCPVPPEQTKGPLGIDPQKG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 TTPTKCHQCTSLMVGLIRQGCSCEVCGFSCHITCVNKAPTTCPVPPEQTKGPLGIDPQKG
             1030      1040      1050      1060      1070      1080

    1040      1050      1060      1070      1080      1090         
pF1KB3 IGTAYEGHVRIPKPAGVKKGWQRALAIVCDFKLFLYDIAEGKASQPSVVISQVIDMRDEE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 IGTAYEGHVRIPKPAGVKKGWQRALAIVCDFKLFLYDIAEGKASQPSVVISQVIDMRDEE
             1090      1100      1110      1120      1130      1140

    1100      1110      1120      1130      1140      1150         
pF1KB3 FSVSSVLASDVIHASRKDIPCIFRVTASQLSASNNKCSILMLADTENEKNKWVGVLSELH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 FSVSSVLASDVIHASRKDIPCIFRVTASQLSASNNKCSILMLADTENEKNKWVGVLSELH
             1150      1160      1170      1180      1190      1200

    1160      1170      1180      1190      1200      1210         
pF1KB3 KILKKNKFRDRSVYVPKEAYDSTLPLIKTTQAAAIIDHERIALGNEEGLFVVHVTKDEII
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 KILKKNKFRDRSVYVPKEAYDSTLPLIKTTQAAAIIDHERIALGNEEGLFVVHVTKDEII
             1210      1220      1230      1240      1250      1260

    1220      1230      1240      1250      1260      1270         
pF1KB3 RVGDNKKIHQIELIPNDQLVAVISGRNRHVRLFPMSALDGRETDFYKLSETKGCQTVTSG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 RVGDNKKIHQIELIPNDQLVAVISGRNRHVRLFPMSALDGRETDFYKLSETKGCQTVTSG
             1270      1280      1290      1300      1310      1320

    1280      1290      1300      1310      1320      1330         
pF1KB3 KVRHGALTCLCVAMKRQVLCYELFQSKTRHRKFKEIQVPYNVQWMAIFSEQLCVGFQSGF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 KVRHGALTCLCVAMKRQVLCYELFQSKTRHRKFKEIQVPYNVQWMAIFSEQLCVGFQSGF
             1330      1340      1350      1360      1370      1380

    1340      1350      1360      1370      1380      1390         
pF1KB3 LRYPLNGEGNPYSMLHSNDHTLSFIAHQPMDAICAVEISSKEYLLCFNSIGIYTDCQGRR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LRYPLNGEGNPYSMLHSNDHTLSFIAHQPMDAICAVEISSKEYLLCFNSIGIYTDCQGRR
             1390      1400      1410      1420      1430      1440

    1400      1410      1420      1430      1440      1450         
pF1KB3 SRQQELMWPANPSSCCYNAPYLSVYSENAVDIFDVNSMEWIQTLPLKKVRPLNNEGSLNL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SRQQELMWPANPSSCCYNAPYLSVYSENAVDIFDVNSMEWIQTLPLKKVRPLNNEGSLNL
             1450      1460      1470      1480      1490      1500

    1460      1470      1480      1490      1500      1510         
pF1KB3 LGLETIRLIYFKNKMAEGDELVVPETSDNSRKQMVRNINNKRRYSFRVPEEERMQQRREM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LGLETIRLIYFKNKMAEGDELVVPETSDNSRKQMVRNINNKRRYSFRVPEEERMQQRREM
             1510      1520      1530      1540      1550      1560

    1520      1530      1540      1550      1560      1570         
pF1KB3 LRDPEMRNKLISNPTNFNHIAHMGPGDGIQILKDLPMNPRPQESRTVFSGSVSIPSITKS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LRDPEMRNKLISNPTNFNHIAHMGPGDGIQILKDLPMNPRPQESRTVFSGSVSIPSITKS
             1570      1580      1590      1600      1610      1620

    1580      1590      1600      1610      1620      1630         
pF1KB3 RPEPGRSMSASSGLSARSSAQNGSALKREFSGGSYSAKRQPMPSPSEGSLSSGGMDQGSD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 RPEPGRSMSASSGLSARSSAQNGSALKREFSGGSYSAKRQPMPSPSEGSLSSGGMDQGSD
             1630      1640      1650      1660      1670      1680

    1640      1650      1660      1670      1680      1690 
pF1KB3 APARDFDGEDSDSPRHSTASNSSNLSSPPSPVSPRKTKSLSLESTDRGSWDP
       :::::::::::::::::::::::::::::::.:::::::::::         
XP_005 APARDFDGEDSDSPRHSTASNSSNLSSPPSPASPRKTKSLSLESTDRGSWDP
             1690      1700      1710      1720      1730  

>>XP_016858067 (OMIM: 603412) PREDICTED: serine/threonin  (1767 aa)
 initn: 6296 init1: 6296 opt: 6296  Z-score: 1908.0  bits: 366.1 E(85289): 1.5e-99
Smith-Waterman score: 10707; 95.6% identity (95.6% similar) in 1723 aa overlap (1-1647:1-1723)

               10        20        30        40        50        60
pF1KB3 MSGEVRLRQLEQFILDGPAQTNGQCFSVETLLDILICLYDECNNSPLRREKNILEYLEWA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MSGEVRLRQLEQFILDGPAQTNGQCFSVETLLDILICLYDECNNSPLRREKNILEYLEWA
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB3 KPFTSKVKQMRLHREDFEILKVIGRGAFGEVAVVKLKNADKVFAMKILNKWEMLKRAETA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KPFTSKVKQMRLHREDFEILKVIGRGAFGEVAVVKLKNADKVFAMKILNKWEMLKRAETA
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB3 CFREERDVLVNGDNKWITTLHYAFQDDNNLYLVMDYYVGGDLLTLLSKFEDRLPEDMARF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 CFREERDVLVNGDNKWITTLHYAFQDDNNLYLVMDYYVGGDLLTLLSKFEDRLPEDMARF
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB3 YLAEMVIAIDSVHQLHYVHRDIKPDNILMDMNGHIRLADFGSCLKLMEDGTVQSSVAVGT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 YLAEMVIAIDSVHQLHYVHRDIKPDNILMDMNGHIRLADFGSCLKLMEDGTVQSSVAVGT
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB3 PDYISPEILQAMEDGKGRYGPECDWWSLGVCMYEMLYGETPFYAESLVETYGKIMNHKER
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PDYISPEILQAMEDGKGRYGPECDWWSLGVCMYEMLYGETPFYAESLVETYGKIMNHKER
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KB3 FQFPAQVTDVSENAKDLIRRLICSREHRLGQNGIEDFKKHPFFSGIDWDNIRNCEAPYIP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FQFPAQVTDVSENAKDLIRRLICSREHRLGQNGIEDFKKHPFFSGIDWDNIRNCEAPYIP
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KB3 EVSSPTDTSNFDVDDDCLKNSETMPPPTHTAFSGHHLPFVGFTYTSSCVLSDRSCLRVTA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EVSSPTDTSNFDVDDDCLKNSETMPPPTHTAFSGHHLPFVGFTYTSSCVLSDRSCLRVTA
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KB3 GPTSLDLDVNVQRTLDNNLATEAYERRIKRLEQEKLELSRKLQESTQTVQALQYSTVDGP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GPTSLDLDVNVQRTLDNNLATEAYERRIKRLEQEKLELSRKLQESTQTVQALQYSTVDGP
              430       440       450       460       470       480

              490       500       510       520       530       540
pF1KB3 LTASKDLEIKNLKEEIEKLRKQVTESSHLEQQLEEANAVRQELDDAFRQIKAYEKQIKTL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LTASKDLEIKNLKEEIEKLRKQVTESSHLEQQLEEANAVRQELDDAFRQIKAYEKQIKTL
              490       500       510       520       530       540

              550       560       570       580       590       600
pF1KB3 QQEREDLNKELVQASERLKNQSKELKDAHCQRKLAMQEFMEINERLTELHTQKQKLARHV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QQEREDLNKELVQASERLKNQSKELKDAHCQRKLAMQEFMEINERLTELHTQKQKLARHV
              550       560       570       580       590       600

              610       620       630       640       650       660
pF1KB3 RDKEEEVDLVMQKVESLRQELRRTERAKKELEVHTEALAAEASKDRKLREQSEHYSKQLE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RDKEEEVDLVMQKVESLRQELRRTERAKKELEVHTEALAAEASKDRKLREQSEHYSKQLE
              610       620       630       640       650       660

              670       680       690       700       710       720
pF1KB3 NELEGLKQKQISYSPGVCSIEHQQEITKLKTDLEKKSIFYEEELSKREGIHANEIKNLKK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NELEGLKQKQISYSPGVCSIEHQQEITKLKTDLEKKSIFYEEELSKREGIHANEIKNLKK
              670       680       690       700       710       720

              730       740       750       760       770       780
pF1KB3 ELHDSEGQQLALNKEIMILKDKLEKTRRESQSEREEFESEFKQQYEREKVLLTEENKKLT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ELHDSEGQQLALNKEIMILKDKLEKTRRESQSEREEFESEFKQQYEREKVLLTEENKKLT
              730       740       750       760       770       780

              790       800       810       820       830       840
pF1KB3 SELDKLTTLYENLSIHNQQLEEEVKDLADKKESVAHWEAQITEIIQWVSDEKDARGYLQA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SELDKLTTLYENLSIHNQQLEEEVKDLADKKESVAHWEAQITEIIQWVSDEKDARGYLQA
              790       800       810       820       830       840

              850       860       870       880       890       900
pF1KB3 LASKMTEELEALRNSSLGTRATDMPWKMRRFAKLDMSARLELQSALDAEIRAKQAIQEEL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LASKMTEELEALRNSSLGTRATDMPWKMRRFAKLDMSARLELQSALDAEIRAKQAIQEEL
              850       860       870       880       890       900

              910       920       930       940       950       960
pF1KB3 NKVKASNIITECKLKDSEKKNLELLSEIEQLIKDTEELRSEKGIEHQDSQHSFLAFLNTP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NKVKASNIITECKLKDSEKKNLELLSEIEQLIKDTEELRSEKGIEHQDSQHSFLAFLNTP
              910       920       930       940       950       960

                                                                   
pF1KB3 TDALDQFER---------------------------------------------------
       :::::::::                                                   
XP_016 TDALDQFERSPSCTPASKGRRTDPVENTYVWNPSVKFHIQSRSTSPSTSSEAEPVKTVDS
              970       980       990      1000      1010      1020

                              970       980       990      1000    
pF1KB3 -------------------------KTHQFFVKSFTTPTKCHQCTSLMVGLIRQGCSCEV
                                :::::::::::::::::::::::::::::::::::
XP_016 TPLSVHTPTLRKKGCPGSTGFPPKRKTHQFFVKSFTTPTKCHQCTSLMVGLIRQGCSCEV
             1030      1040      1050      1060      1070      1080

         1010      1020      1030      1040      1050      1060    
pF1KB3 CGFSCHITCVNKAPTTCPVPPEQTKGPLGIDPQKGIGTAYEGHVRIPKPAGVKKGWQRAL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 CGFSCHITCVNKAPTTCPVPPEQTKGPLGIDPQKGIGTAYEGHVRIPKPAGVKKGWQRAL
             1090      1100      1110      1120      1130      1140

         1070      1080      1090      1100      1110      1120    
pF1KB3 AIVCDFKLFLYDIAEGKASQPSVVISQVIDMRDEEFSVSSVLASDVIHASRKDIPCIFRV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AIVCDFKLFLYDIAEGKASQPSVVISQVIDMRDEEFSVSSVLASDVIHASRKDIPCIFRV
             1150      1160      1170      1180      1190      1200

         1130      1140      1150      1160      1170      1180    
pF1KB3 TASQLSASNNKCSILMLADTENEKNKWVGVLSELHKILKKNKFRDRSVYVPKEAYDSTLP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TASQLSASNNKCSILMLADTENEKNKWVGVLSELHKILKKNKFRDRSVYVPKEAYDSTLP
             1210      1220      1230      1240      1250      1260

         1190      1200      1210      1220      1230      1240    
pF1KB3 LIKTTQAAAIIDHERIALGNEEGLFVVHVTKDEIIRVGDNKKIHQIELIPNDQLVAVISG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LIKTTQAAAIIDHERIALGNEEGLFVVHVTKDEIIRVGDNKKIHQIELIPNDQLVAVISG
             1270      1280      1290      1300      1310      1320

         1250      1260      1270      1280      1290      1300    
pF1KB3 RNRHVRLFPMSALDGRETDFYKLSETKGCQTVTSGKVRHGALTCLCVAMKRQVLCYELFQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RNRHVRLFPMSALDGRETDFYKLSETKGCQTVTSGKVRHGALTCLCVAMKRQVLCYELFQ
             1330      1340      1350      1360      1370      1380

         1310      1320      1330      1340      1350      1360    
pF1KB3 SKTRHRKFKEIQVPYNVQWMAIFSEQLCVGFQSGFLRYPLNGEGNPYSMLHSNDHTLSFI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SKTRHRKFKEIQVPYNVQWMAIFSEQLCVGFQSGFLRYPLNGEGNPYSMLHSNDHTLSFI
             1390      1400      1410      1420      1430      1440

         1370      1380      1390      1400      1410      1420    
pF1KB3 AHQPMDAICAVEISSKEYLLCFNSIGIYTDCQGRRSRQQELMWPANPSSCCYNAPYLSVY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AHQPMDAICAVEISSKEYLLCFNSIGIYTDCQGRRSRQQELMWPANPSSCCYNAPYLSVY
             1450      1460      1470      1480      1490      1500

         1430      1440      1450      1460      1470      1480    
pF1KB3 SENAVDIFDVNSMEWIQTLPLKKVRPLNNEGSLNLLGLETIRLIYFKNKMAEGDELVVPE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SENAVDIFDVNSMEWIQTLPLKKVRPLNNEGSLNLLGLETIRLIYFKNKMAEGDELVVPE
             1510      1520      1530      1540      1550      1560

         1490      1500      1510      1520      1530      1540    
pF1KB3 TSDNSRKQMVRNINNKRRYSFRVPEEERMQQRREMLRDPEMRNKLISNPTNFNHIAHMGP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TSDNSRKQMVRNINNKRRYSFRVPEEERMQQRREMLRDPEMRNKLISNPTNFNHIAHMGP
             1570      1580      1590      1600      1610      1620

         1550      1560      1570      1580      1590      1600    
pF1KB3 GDGIQILKDLPMNPRPQESRTVFSGSVSIPSITKSRPEPGRSMSASSGLSARSSAQNGSA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GDGIQILKDLPMNPRPQESRTVFSGSVSIPSITKSRPEPGRSMSASSGLSARSSAQNGSA
             1630      1640      1650      1660      1670      1680

         1610      1620      1630      1640      1650      1660    
pF1KB3 LKREFSGGSYSAKRQPMPSPSEGSLSSGGMDQGSDAPARDFDGEDSDSPRHSTASNSSNL
       :::::::::::::::::::::::::::::::::::::::::::                 
XP_016 LKREFSGGSYSAKRQPMPSPSEGSLSSGGMDQGSDAPARDFDGEDSDSPRHSTASNSSNL
             1690      1700      1710      1720      1730      1740

         1670      1680      1690 
pF1KB3 SSPPSPVSPRKTKSLSLESTDRGSWDP
                                  
XP_016 SSPPSPASPRKTKSLSLESTDRGSWDP
             1750      1760       

>>XP_005273377 (OMIM: 603412) PREDICTED: serine/threonin  (1794 aa)
 initn: 10286 init1: 6296 opt: 6296  Z-score: 1907.9  bits: 366.1 E(85289): 1.6e-99
Smith-Waterman score: 10454; 94.0% identity (94.0% similar) in 1723 aa overlap (1-1620:1-1723)

               10        20        30        40        50        60
pF1KB3 MSGEVRLRQLEQFILDGPAQTNGQCFSVETLLDILICLYDECNNSPLRREKNILEYLEWA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MSGEVRLRQLEQFILDGPAQTNGQCFSVETLLDILICLYDECNNSPLRREKNILEYLEWA
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB3 KPFTSKVKQMRLHREDFEILKVIGRGAFGEVAVVKLKNADKVFAMKILNKWEMLKRAETA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 KPFTSKVKQMRLHREDFEILKVIGRGAFGEVAVVKLKNADKVFAMKILNKWEMLKRAETA
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB3 CFREERDVLVNGDNKWITTLHYAFQDDNNLYLVMDYYVGGDLLTLLSKFEDRLPEDMARF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 CFREERDVLVNGDNKWITTLHYAFQDDNNLYLVMDYYVGGDLLTLLSKFEDRLPEDMARF
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB3 YLAEMVIAIDSVHQLHYVHRDIKPDNILMDMNGHIRLADFGSCLKLMEDGTVQSSVAVGT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 YLAEMVIAIDSVHQLHYVHRDIKPDNILMDMNGHIRLADFGSCLKLMEDGTVQSSVAVGT
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB3 PDYISPEILQAMEDGKGRYGPECDWWSLGVCMYEMLYGETPFYAESLVETYGKIMNHKER
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 PDYISPEILQAMEDGKGRYGPECDWWSLGVCMYEMLYGETPFYAESLVETYGKIMNHKER
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KB3 FQFPAQVTDVSENAKDLIRRLICSREHRLGQNGIEDFKKHPFFSGIDWDNIRNCEAPYIP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 FQFPAQVTDVSENAKDLIRRLICSREHRLGQNGIEDFKKHPFFSGIDWDNIRNCEAPYIP
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KB3 EVSSPTDTSNFDVDDDCLKNSETMPPPTHTAFSGHHLPFVGFTYTSSCVLSDRSCLRVTA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 EVSSPTDTSNFDVDDDCLKNSETMPPPTHTAFSGHHLPFVGFTYTSSCVLSDRSCLRVTA
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KB3 GPTSLDLDVNVQRTLDNNLATEAYERRIKRLEQEKLELSRKLQESTQTVQALQYSTVDGP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 GPTSLDLDVNVQRTLDNNLATEAYERRIKRLEQEKLELSRKLQESTQTVQALQYSTVDGP
              430       440       450       460       470       480

              490       500       510       520       530       540
pF1KB3 LTASKDLEIKNLKEEIEKLRKQVTESSHLEQQLEEANAVRQELDDAFRQIKAYEKQIKTL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LTASKDLEIKNLKEEIEKLRKQVTESSHLEQQLEEANAVRQELDDAFRQIKAYEKQIKTL
              490       500       510       520       530       540

              550       560       570       580       590       600
pF1KB3 QQEREDLNKELVQASERLKNQSKELKDAHCQRKLAMQEFMEINERLTELHTQKQKLARHV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 QQEREDLNKELVQASERLKNQSKELKDAHCQRKLAMQEFMEINERLTELHTQKQKLARHV
              550       560       570       580       590       600

              610       620       630       640       650       660
pF1KB3 RDKEEEVDLVMQKVESLRQELRRTERAKKELEVHTEALAAEASKDRKLREQSEHYSKQLE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 RDKEEEVDLVMQKVESLRQELRRTERAKKELEVHTEALAAEASKDRKLREQSEHYSKQLE
              610       620       630       640       650       660

              670       680       690       700       710       720
pF1KB3 NELEGLKQKQISYSPGVCSIEHQQEITKLKTDLEKKSIFYEEELSKREGIHANEIKNLKK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 NELEGLKQKQISYSPGVCSIEHQQEITKLKTDLEKKSIFYEEELSKREGIHANEIKNLKK
              670       680       690       700       710       720

              730       740       750       760       770       780
pF1KB3 ELHDSEGQQLALNKEIMILKDKLEKTRRESQSEREEFESEFKQQYEREKVLLTEENKKLT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 ELHDSEGQQLALNKEIMILKDKLEKTRRESQSEREEFESEFKQQYEREKVLLTEENKKLT
              730       740       750       760       770       780

              790       800       810       820       830       840
pF1KB3 SELDKLTTLYENLSIHNQQLEEEVKDLADKKESVAHWEAQITEIIQWVSDEKDARGYLQA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SELDKLTTLYENLSIHNQQLEEEVKDLADKKESVAHWEAQITEIIQWVSDEKDARGYLQA
              790       800       810       820       830       840

              850       860       870       880       890       900
pF1KB3 LASKMTEELEALRNSSLGTRATDMPWKMRRFAKLDMSARLELQSALDAEIRAKQAIQEEL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LASKMTEELEALRNSSLGTRATDMPWKMRRFAKLDMSARLELQSALDAEIRAKQAIQEEL
              850       860       870       880       890       900

              910       920       930       940       950       960
pF1KB3 NKVKASNIITECKLKDSEKKNLELLSEIEQLIKDTEELRSEKGIEHQDSQHSFLAFLNTP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 NKVKASNIITECKLKDSEKKNLELLSEIEQLIKDTEELRSEKGIEHQDSQHSFLAFLNTP
              910       920       930       940       950       960

                                                       970         
pF1KB3 TDALDQFER-----------------------------------------KTHQFFVKSF
       :::::::::                                         ::::::::::
XP_005 TDALDQFERSPSCTPASKGRRTVDSTPLSVHTPTLRKKGCPGSTGFPPKRKTHQFFVKSF
              970       980       990      1000      1010      1020

     980       990      1000      1010      1020      1030         
pF1KB3 TTPTKCHQCTSLMVGLIRQGCSCEVCGFSCHITCVNKAPTTCPVPPEQTKGPLGIDPQKG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 TTPTKCHQCTSLMVGLIRQGCSCEVCGFSCHITCVNKAPTTCPVPPEQTKGPLGIDPQKG
             1030      1040      1050      1060      1070      1080

    1040      1050      1060      1070      1080      1090         
pF1KB3 IGTAYEGHVRIPKPAGVKKGWQRALAIVCDFKLFLYDIAEGKASQPSVVISQVIDMRDEE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 IGTAYEGHVRIPKPAGVKKGWQRALAIVCDFKLFLYDIAEGKASQPSVVISQVIDMRDEE
             1090      1100      1110      1120      1130      1140

    1100      1110      1120      1130      1140      1150         
pF1KB3 FSVSSVLASDVIHASRKDIPCIFRVTASQLSASNNKCSILMLADTENEKNKWVGVLSELH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 FSVSSVLASDVIHASRKDIPCIFRVTASQLSASNNKCSILMLADTENEKNKWVGVLSELH
             1150      1160      1170      1180      1190      1200

    1160      1170      1180      1190      1200      1210         
pF1KB3 KILKKNKFRDRSVYVPKEAYDSTLPLIKTTQAAAIIDHERIALGNEEGLFVVHVTKDEII
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 KILKKNKFRDRSVYVPKEAYDSTLPLIKTTQAAAIIDHERIALGNEEGLFVVHVTKDEII
             1210      1220      1230      1240      1250      1260

    1220      1230      1240      1250      1260      1270         
pF1KB3 RVGDNKKIHQIELIPNDQLVAVISGRNRHVRLFPMSALDGRETDFYKLSETKGCQTVTSG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 RVGDNKKIHQIELIPNDQLVAVISGRNRHVRLFPMSALDGRETDFYKLSETKGCQTVTSG
             1270      1280      1290      1300      1310      1320

    1280      1290      1300      1310      1320      1330         
pF1KB3 KVRHGALTCLCVAMKRQVLCYELFQSKTRHRKFKEIQVPYNVQWMAIFSEQLCVGFQSGF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 KVRHGALTCLCVAMKRQVLCYELFQSKTRHRKFKEIQVPYNVQWMAIFSEQLCVGFQSGF
             1330      1340      1350      1360      1370      1380

    1340      1350      1360      1370      1380      1390         
pF1KB3 LRYPLNGEGNPYSMLHSNDHTLSFIAHQPMDAICAVEISSKEYLLCFNSIGIYTDCQGRR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LRYPLNGEGNPYSMLHSNDHTLSFIAHQPMDAICAVEISSKEYLLCFNSIGIYTDCQGRR
             1390      1400      1410      1420      1430      1440

    1400      1410      1420      1430      1440      1450         
pF1KB3 SRQQELMWPANPSSCCYNAPYLSVYSENAVDIFDVNSMEWIQTLPLKKVRPLNNEGSLNL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SRQQELMWPANPSSCCYNAPYLSVYSENAVDIFDVNSMEWIQTLPLKKVRPLNNEGSLNL
             1450      1460      1470      1480      1490      1500

    1460      1470      1480      1490      1500      1510         
pF1KB3 LGLETIRLIYFKNKMAEGDELVVPETSDNSRKQMVRNINNKRRYSFRVPEEERMQQRREM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LGLETIRLIYFKNKMAEGDELVVPETSDNSRKQMVRNINNKRRYSFRVPEEERMQQRREM
             1510      1520      1530      1540      1550      1560

    1520      1530      1540      1550                             
pF1KB3 LRDPEMRNKLISNPTNFNHIAHMGPGDGIQILKDLPM-----------------------
       :::::::::::::::::::::::::::::::::::::                       
XP_005 LRDPEMRNKLISNPTNFNHIAHMGPGDGIQILKDLPMPGFPYPSPHHHSGLISSPINFEH
             1570      1580      1590      1600      1610      1620

                                              1560      1570       
pF1KB3 ---------------------------------------NPRPQESRTVFSGSVSIPSIT
                                              :::::::::::::::::::::
XP_005 IYHMTVNSAEKFLSPDSINPEYSPSLRSVPGTPSFMTLRNPRPQESRTVFSGSVSIPSIT
             1630      1640      1650      1660      1670      1680

      1580      1590      1600      1610      1620      1630       
pF1KB3 KSRPEPGRSMSASSGLSARSSAQNGSALKREFSGGSYSAKRQPMPSPSEGSLSSGGMDQG
       :::::::::::::::::::::::::::::::::::::::::::                 
XP_005 KSRPEPGRSMSASSGLSARSSAQNGSALKREFSGGSYSAKRQPMPSPSEGSLSSGGMDQG
             1690      1700      1710      1720      1730      1740

      1640      1650      1660      1670      1680      1690 
pF1KB3 SDAPARDFDGEDSDSPRHSTASNSSNLSSPPSPVSPRKTKSLSLESTDRGSWDP
                                                             
XP_005 SDAPARDFDGEDSDSPRHSTASNSSNLSSPPSPASPRKTKSLSLESTDRGSWDP
             1750      1760      1770      1780      1790    

>>XP_005273375 (OMIM: 603412) PREDICTED: serine/threonin  (1829 aa)
 initn: 10286 init1: 6296 opt: 6296  Z-score: 1907.8  bits: 366.2 E(85289): 1.6e-99
Smith-Waterman score: 10169; 92.0% identity (92.0% similar) in 1723 aa overlap (1-1585:1-1723)

               10        20        30        40        50        60
pF1KB3 MSGEVRLRQLEQFILDGPAQTNGQCFSVETLLDILICLYDECNNSPLRREKNILEYLEWA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MSGEVRLRQLEQFILDGPAQTNGQCFSVETLLDILICLYDECNNSPLRREKNILEYLEWA
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB3 KPFTSKVKQMRLHREDFEILKVIGRGAFGEVAVVKLKNADKVFAMKILNKWEMLKRAETA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 KPFTSKVKQMRLHREDFEILKVIGRGAFGEVAVVKLKNADKVFAMKILNKWEMLKRAETA
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB3 CFREERDVLVNGDNKWITTLHYAFQDDNNLYLVMDYYVGGDLLTLLSKFEDRLPEDMARF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 CFREERDVLVNGDNKWITTLHYAFQDDNNLYLVMDYYVGGDLLTLLSKFEDRLPEDMARF
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB3 YLAEMVIAIDSVHQLHYVHRDIKPDNILMDMNGHIRLADFGSCLKLMEDGTVQSSVAVGT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 YLAEMVIAIDSVHQLHYVHRDIKPDNILMDMNGHIRLADFGSCLKLMEDGTVQSSVAVGT
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB3 PDYISPEILQAMEDGKGRYGPECDWWSLGVCMYEMLYGETPFYAESLVETYGKIMNHKER
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 PDYISPEILQAMEDGKGRYGPECDWWSLGVCMYEMLYGETPFYAESLVETYGKIMNHKER
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KB3 FQFPAQVTDVSENAKDLIRRLICSREHRLGQNGIEDFKKHPFFSGIDWDNIRNCEAPYIP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 FQFPAQVTDVSENAKDLIRRLICSREHRLGQNGIEDFKKHPFFSGIDWDNIRNCEAPYIP
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KB3 EVSSPTDTSNFDVDDDCLKNSETMPPPTHTAFSGHHLPFVGFTYTSSCVLSDRSCLRVTA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 EVSSPTDTSNFDVDDDCLKNSETMPPPTHTAFSGHHLPFVGFTYTSSCVLSDRSCLRVTA
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KB3 GPTSLDLDVNVQRTLDNNLATEAYERRIKRLEQEKLELSRKLQESTQTVQALQYSTVDGP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 GPTSLDLDVNVQRTLDNNLATEAYERRIKRLEQEKLELSRKLQESTQTVQALQYSTVDGP
              430       440       450       460       470       480

              490       500       510       520       530       540
pF1KB3 LTASKDLEIKNLKEEIEKLRKQVTESSHLEQQLEEANAVRQELDDAFRQIKAYEKQIKTL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LTASKDLEIKNLKEEIEKLRKQVTESSHLEQQLEEANAVRQELDDAFRQIKAYEKQIKTL
              490       500       510       520       530       540

              550       560       570       580       590       600
pF1KB3 QQEREDLNKELVQASERLKNQSKELKDAHCQRKLAMQEFMEINERLTELHTQKQKLARHV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 QQEREDLNKELVQASERLKNQSKELKDAHCQRKLAMQEFMEINERLTELHTQKQKLARHV
              550       560       570       580       590       600

              610       620       630       640       650       660
pF1KB3 RDKEEEVDLVMQKVESLRQELRRTERAKKELEVHTEALAAEASKDRKLREQSEHYSKQLE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 RDKEEEVDLVMQKVESLRQELRRTERAKKELEVHTEALAAEASKDRKLREQSEHYSKQLE
              610       620       630       640       650       660

              670       680       690       700       710       720
pF1KB3 NELEGLKQKQISYSPGVCSIEHQQEITKLKTDLEKKSIFYEEELSKREGIHANEIKNLKK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 NELEGLKQKQISYSPGVCSIEHQQEITKLKTDLEKKSIFYEEELSKREGIHANEIKNLKK
              670       680       690       700       710       720

              730       740       750       760       770       780
pF1KB3 ELHDSEGQQLALNKEIMILKDKLEKTRRESQSEREEFESEFKQQYEREKVLLTEENKKLT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 ELHDSEGQQLALNKEIMILKDKLEKTRRESQSEREEFESEFKQQYEREKVLLTEENKKLT
              730       740       750       760       770       780

              790       800       810       820       830       840
pF1KB3 SELDKLTTLYENLSIHNQQLEEEVKDLADKKESVAHWEAQITEIIQWVSDEKDARGYLQA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SELDKLTTLYENLSIHNQQLEEEVKDLADKKESVAHWEAQITEIIQWVSDEKDARGYLQA
              790       800       810       820       830       840

              850       860       870       880       890       900
pF1KB3 LASKMTEELEALRNSSLGTRATDMPWKMRRFAKLDMSARLELQSALDAEIRAKQAIQEEL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LASKMTEELEALRNSSLGTRATDMPWKMRRFAKLDMSARLELQSALDAEIRAKQAIQEEL
              850       860       870       880       890       900

              910       920       930       940       950       960
pF1KB3 NKVKASNIITECKLKDSEKKNLELLSEIEQLIKDTEELRSEKGIEHQDSQHSFLAFLNTP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 NKVKASNIITECKLKDSEKKNLELLSEIEQLIKDTEELRSEKGIEHQDSQHSFLAFLNTP
              910       920       930       940       950       960

                                                                   
pF1KB3 TDALDQFER---------------------------------------------------
       :::::::::                                                   
XP_005 TDALDQFERSPSCTPASKGRRTDPVENTYVWNPSVKFHIQSRSTSPSTSSEAEPVKTVDS
              970       980       990      1000      1010      1020

                              970       980       990      1000    
pF1KB3 -------------------------KTHQFFVKSFTTPTKCHQCTSLMVGLIRQGCSCEV
                                :::::::::::::::::::::::::::::::::::
XP_005 TPLSVHTPTLRKKGCPGSTGFPPKRKTHQFFVKSFTTPTKCHQCTSLMVGLIRQGCSCEV
             1030      1040      1050      1060      1070      1080

         1010      1020      1030      1040      1050      1060    
pF1KB3 CGFSCHITCVNKAPTTCPVPPEQTKGPLGIDPQKGIGTAYEGHVRIPKPAGVKKGWQRAL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 CGFSCHITCVNKAPTTCPVPPEQTKGPLGIDPQKGIGTAYEGHVRIPKPAGVKKGWQRAL
             1090      1100      1110      1120      1130      1140

         1070      1080      1090      1100      1110      1120    
pF1KB3 AIVCDFKLFLYDIAEGKASQPSVVISQVIDMRDEEFSVSSVLASDVIHASRKDIPCIFRV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 AIVCDFKLFLYDIAEGKASQPSVVISQVIDMRDEEFSVSSVLASDVIHASRKDIPCIFRV
             1150      1160      1170      1180      1190      1200

         1130      1140      1150      1160      1170      1180    
pF1KB3 TASQLSASNNKCSILMLADTENEKNKWVGVLSELHKILKKNKFRDRSVYVPKEAYDSTLP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 TASQLSASNNKCSILMLADTENEKNKWVGVLSELHKILKKNKFRDRSVYVPKEAYDSTLP
             1210      1220      1230      1240      1250      1260

         1190      1200      1210      1220      1230      1240    
pF1KB3 LIKTTQAAAIIDHERIALGNEEGLFVVHVTKDEIIRVGDNKKIHQIELIPNDQLVAVISG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LIKTTQAAAIIDHERIALGNEEGLFVVHVTKDEIIRVGDNKKIHQIELIPNDQLVAVISG
             1270      1280      1290      1300      1310      1320

         1250      1260      1270      1280      1290      1300    
pF1KB3 RNRHVRLFPMSALDGRETDFYKLSETKGCQTVTSGKVRHGALTCLCVAMKRQVLCYELFQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 RNRHVRLFPMSALDGRETDFYKLSETKGCQTVTSGKVRHGALTCLCVAMKRQVLCYELFQ
             1330      1340      1350      1360      1370      1380

         1310      1320      1330      1340      1350      1360    
pF1KB3 SKTRHRKFKEIQVPYNVQWMAIFSEQLCVGFQSGFLRYPLNGEGNPYSMLHSNDHTLSFI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SKTRHRKFKEIQVPYNVQWMAIFSEQLCVGFQSGFLRYPLNGEGNPYSMLHSNDHTLSFI
             1390      1400      1410      1420      1430      1440

         1370      1380      1390      1400      1410      1420    
pF1KB3 AHQPMDAICAVEISSKEYLLCFNSIGIYTDCQGRRSRQQELMWPANPSSCCYNAPYLSVY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 AHQPMDAICAVEISSKEYLLCFNSIGIYTDCQGRRSRQQELMWPANPSSCCYNAPYLSVY
             1450      1460      1470      1480      1490      1500

         1430      1440      1450      1460      1470      1480    
pF1KB3 SENAVDIFDVNSMEWIQTLPLKKVRPLNNEGSLNLLGLETIRLIYFKNKMAEGDELVVPE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SENAVDIFDVNSMEWIQTLPLKKVRPLNNEGSLNLLGLETIRLIYFKNKMAEGDELVVPE
             1510      1520      1530      1540      1550      1560

         1490      1500      1510      1520      1530      1540    
pF1KB3 TSDNSRKQMVRNINNKRRYSFRVPEEERMQQRREMLRDPEMRNKLISNPTNFNHIAHMGP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 TSDNSRKQMVRNINNKRRYSFRVPEEERMQQRREMLRDPEMRNKLISNPTNFNHIAHMGP
             1570      1580      1590      1600      1610      1620

         1550                                                      
pF1KB3 GDGIQILKDLPM------------------------------------------------
       ::::::::::::                                                
XP_005 GDGIQILKDLPMPGFPYPSPHHHSGLISSPINFEHIYHMTVNSAEKFLSPDSINPEYSPS
             1630      1640      1650      1660      1670      1680

                     1560      1570      1580      1590      1600  
pF1KB3 --------------NPRPQESRTVFSGSVSIPSITKSRPEPGRSMSASSGLSARSSAQNG
                     :::::::::::::::::::::::::::::                 
XP_005 LRSVPGTPSFMTLRNPRPQESRTVFSGSVSIPSITKSRPEPGRSMSASSGLSARSSAQNG
             1690      1700      1710      1720      1730      1740

           1610      1620      1630      1640      1650      1660  
pF1KB3 SALKREFSGGSYSAKRQPMPSPSEGSLSSGGMDQGSDAPARDFDGEDSDSPRHSTASNSS
                                                                   
XP_005 SALKREFSGGSYSAKRQPMPSPSEGSLSSGGMDQGSDAPARDFDGEDSDSPRHSTASNSS
             1750      1760      1770      1780      1790      1800

>--
 initn: 693 init1: 693 opt: 693  Z-score: 236.4  bits: 56.9 E(85289): 2e-06
Smith-Waterman score: 693; 99.1% identity (100.0% similar) in 106 aa overlap (1586-1691:1724-1829)

        1560      1570      1580      1590      1600      1610     
pF1KB3 MNPRPQESRTVFSGSVSIPSITKSRPEPGRSMSASSGLSARSSAQNGSALKREFSGGSYS
                                     ::::::::::::::::::::::::::::::
XP_005 RNPRPQESRTVFSGSVSIPSITKSRPEPGRSMSASSGLSARSSAQNGSALKREFSGGSYS
          1700      1710      1720      1730      1740      1750   

        1620      1630      1640      1650      1660      1670     
pF1KB3 AKRQPMPSPSEGSLSSGGMDQGSDAPARDFDGEDSDSPRHSTASNSSNLSSPPSPVSPRK
       :::::::::::::::::::::::::::::::::::::::::::::::::::::::.::::
XP_005 AKRQPMPSPSEGSLSSGGMDQGSDAPARDFDGEDSDSPRHSTASNSSNLSSPPSPASPRK
          1760      1770      1780      1790      1800      1810   

        1680      1690 
pF1KB3 TKSLSLESTDRGSWDP
       ::::::::::::::::
XP_005 TKSLSLESTDRGSWDP
          1820         

>>XP_016858071 (OMIM: 603412) PREDICTED: serine/threonin  (1589 aa)
 initn: 10261 init1: 6289 opt: 6289  Z-score: 1906.4  bits: 365.7 E(85289): 1.9e-99
Smith-Waterman score: 10209; 98.0% identity (98.2% similar) in 1587 aa overlap (1-1559:1-1587)

               10        20        30        40        50        60
pF1KB3 MSGEVRLRQLEQFILDGPAQTNGQCFSVETLLDILICLYDECNNSPLRREKNILEYLEWA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MSGEVRLRQLEQFILDGPAQTNGQCFSVETLLDILICLYDECNNSPLRREKNILEYLEWA
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB3 KPFTSKVKQMRLHREDFEILKVIGRGAFGEVAVVKLKNADKVFAMKILNKWEMLKRAETA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KPFTSKVKQMRLHREDFEILKVIGRGAFGEVAVVKLKNADKVFAMKILNKWEMLKRAETA
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB3 CFREERDVLVNGDNKWITTLHYAFQDDNNLYLVMDYYVGGDLLTLLSKFEDRLPEDMARF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 CFREERDVLVNGDNKWITTLHYAFQDDNNLYLVMDYYVGGDLLTLLSKFEDRLPEDMARF
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB3 YLAEMVIAIDSVHQLHYVHRDIKPDNILMDMNGHIRLADFGSCLKLMEDGTVQSSVAVGT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 YLAEMVIAIDSVHQLHYVHRDIKPDNILMDMNGHIRLADFGSCLKLMEDGTVQSSVAVGT
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB3 PDYISPEILQAMEDGKGRYGPECDWWSLGVCMYEMLYGETPFYAESLVETYGKIMNHKER
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PDYISPEILQAMEDGKGRYGPECDWWSLGVCMYEMLYGETPFYAESLVETYGKIMNHKER
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KB3 FQFPAQVTDVSENAKDLIRRLICSREHRLGQNGIEDFKKHPFFSGIDWDNIRNCEAPYIP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FQFPAQVTDVSENAKDLIRRLICSREHRLGQNGIEDFKKHPFFSGIDWDNIRNCEAPYIP
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KB3 EVSSPTDTSNFDVDDDCLKNSETMPPPTHTAFSGHHLPFVGFTYTSSCVLSDRSCLRVTA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EVSSPTDTSNFDVDDDCLKNSETMPPPTHTAFSGHHLPFVGFTYTSSCVLSDRSCLRVTA
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KB3 GPTSLDLDVNVQRTLDNNLATEAYERRIKRLEQEKLELSRKLQESTQTVQALQYSTVDGP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GPTSLDLDVNVQRTLDNNLATEAYERRIKRLEQEKLELSRKLQESTQTVQALQYSTVDGP
              430       440       450       460       470       480

              490       500       510       520       530       540
pF1KB3 LTASKDLEIKNLKEEIEKLRKQVTESSHLEQQLEEANAVRQELDDAFRQIKAYEKQIKTL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LTASKDLEIKNLKEEIEKLRKQVTESSHLEQQLEEANAVRQELDDAFRQIKAYEKQIKTL
              490       500       510       520       530       540

              550       560       570       580       590       600
pF1KB3 QQEREDLNKELVQASERLKNQSKELKDAHCQRKLAMQEFMEINERLTELHTQKQKLARHV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QQEREDLNKELVQASERLKNQSKELKDAHCQRKLAMQEFMEINERLTELHTQKQKLARHV
              550       560       570       580       590       600

              610       620       630       640       650       660
pF1KB3 RDKEEEVDLVMQKVESLRQELRRTERAKKELEVHTEALAAEASKDRKLREQSEHYSKQLE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RDKEEEVDLVMQKVESLRQELRRTERAKKELEVHTEALAAEASKDRKLREQSEHYSKQLE
              610       620       630       640       650       660

              670       680       690       700       710       720
pF1KB3 NELEGLKQKQISYSPGVCSIEHQQEITKLKTDLEKKSIFYEEELSKREGIHANEIKNLKK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NELEGLKQKQISYSPGVCSIEHQQEITKLKTDLEKKSIFYEEELSKREGIHANEIKNLKK
              670       680       690       700       710       720

              730       740       750       760       770       780
pF1KB3 ELHDSEGQQLALNKEIMILKDKLEKTRRESQSEREEFESEFKQQYEREKVLLTEENKKLT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ELHDSEGQQLALNKEIMILKDKLEKTRRESQSEREEFESEFKQQYEREKVLLTEENKKLT
              730       740       750       760       770       780

              790       800       810       820       830       840
pF1KB3 SELDKLTTLYENLSIHNQQLEEEVKDLADKKESVAHWEAQITEIIQWVSDEKDARGYLQA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SELDKLTTLYENLSIHNQQLEEEVKDLADKKESVAHWEAQITEIIQWVSDEKDARGYLQA
              790       800       810       820       830       840

              850       860       870       880       890       900
pF1KB3 LASKMTEELEALRNSSLGTRATDMPWKMRRFAKLDMSARLELQSALDAEIRAKQAIQEEL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LASKMTEELEALRNSSLGTRATDMPWKMRRFAKLDMSARLELQSALDAEIRAKQAIQEEL
              850       860       870       880       890       900

              910       920       930       940       950       960
pF1KB3 NKVKASNIITECKLKDSEKKNLELLSEIEQLIKDTEELRSEKGIEHQDSQHSFLAFLNTP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NKVKASNIITECKLKDSEKKNLELLSEIEQLIKDTEELRSEKGIEHQDSQHSFLAFLNTP
              910       920       930       940       950       960

                                          970       980       990  
pF1KB3 TDALDQFE----------------------------RKTHQFFVKSFTTPTKCHQCTSLM
       ::::::::                            ::::::::::::::::::::::::
XP_016 TDALDQFETVDSTPLSVHTPTLRKKGCPGSTGFPPKRKTHQFFVKSFTTPTKCHQCTSLM
              970       980       990      1000      1010      1020

           1000      1010      1020      1030      1040      1050  
pF1KB3 VGLIRQGCSCEVCGFSCHITCVNKAPTTCPVPPEQTKGPLGIDPQKGIGTAYEGHVRIPK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VGLIRQGCSCEVCGFSCHITCVNKAPTTCPVPPEQTKGPLGIDPQKGIGTAYEGHVRIPK
             1030      1040      1050      1060      1070      1080

           1060      1070      1080      1090      1100      1110  
pF1KB3 PAGVKKGWQRALAIVCDFKLFLYDIAEGKASQPSVVISQVIDMRDEEFSVSSVLASDVIH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PAGVKKGWQRALAIVCDFKLFLYDIAEGKASQPSVVISQVIDMRDEEFSVSSVLASDVIH
             1090      1100      1110      1120      1130      1140

           1120      1130      1140      1150      1160      1170  
pF1KB3 ASRKDIPCIFRVTASQLSASNNKCSILMLADTENEKNKWVGVLSELHKILKKNKFRDRSV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ASRKDIPCIFRVTASQLSASNNKCSILMLADTENEKNKWVGVLSELHKILKKNKFRDRSV
             1150      1160      1170      1180      1190      1200

           1180      1190      1200      1210      1220      1230  
pF1KB3 YVPKEAYDSTLPLIKTTQAAAIIDHERIALGNEEGLFVVHVTKDEIIRVGDNKKIHQIEL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 YVPKEAYDSTLPLIKTTQAAAIIDHERIALGNEEGLFVVHVTKDEIIRVGDNKKIHQIEL
             1210      1220      1230      1240      1250      1260

           1240      1250      1260      1270      1280      1290  
pF1KB3 IPNDQLVAVISGRNRHVRLFPMSALDGRETDFYKLSETKGCQTVTSGKVRHGALTCLCVA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IPNDQLVAVISGRNRHVRLFPMSALDGRETDFYKLSETKGCQTVTSGKVRHGALTCLCVA
             1270      1280      1290      1300      1310      1320

           1300      1310      1320      1330      1340      1350  
pF1KB3 MKRQVLCYELFQSKTRHRKFKEIQVPYNVQWMAIFSEQLCVGFQSGFLRYPLNGEGNPYS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MKRQVLCYELFQSKTRHRKFKEIQVPYNVQWMAIFSEQLCVGFQSGFLRYPLNGEGNPYS
             1330      1340      1350      1360      1370      1380

           1360      1370      1380      1390      1400      1410  
pF1KB3 MLHSNDHTLSFIAHQPMDAICAVEISSKEYLLCFNSIGIYTDCQGRRSRQQELMWPANPS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MLHSNDHTLSFIAHQPMDAICAVEISSKEYLLCFNSIGIYTDCQGRRSRQQELMWPANPS
             1390      1400      1410      1420      1430      1440

           1420      1430      1440      1450      1460      1470  
pF1KB3 SCCYNAPYLSVYSENAVDIFDVNSMEWIQTLPLKKVRPLNNEGSLNLLGLETIRLIYFKN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SCCYNAPYLSVYSENAVDIFDVNSMEWIQTLPLKKVRPLNNEGSLNLLGLETIRLIYFKN
             1450      1460      1470      1480      1490      1500

           1480      1490      1500      1510      1520      1530  
pF1KB3 KMAEGDELVVPETSDNSRKQMVRNINNKRRYSFRVPEEERMQQRREMLRDPEMRNKLISN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KMAEGDELVVPETSDNSRKQMVRNINNKRRYSFRVPEEERMQQRREMLRDPEMRNKLISN
             1510      1520      1530      1540      1550      1560

           1540      1550      1560      1570      1580      1590  
pF1KB3 PTNFNHIAHMGPGDGIQILKDLPMNPRPQESRTVFSGSVSIPSITKSRPEPGRSMSASSG
       ::::::::::::::::::::::::. .                                 
XP_016 PTNFNHIAHMGPGDGIQILKDLPMDKKLV                               
             1570      1580                                        

>>NP_003598 (OMIM: 603412) serine/threonine-protein kina  (1719 aa)
 initn: 6289 init1: 6289 opt: 6289  Z-score: 1906.0  bits: 365.7 E(85289): 2e-99
Smith-Waterman score: 11092; 98.3% identity (98.4% similar) in 1719 aa overlap (1-1691:1-1719)

               10        20        30        40        50        60
pF1KB3 MSGEVRLRQLEQFILDGPAQTNGQCFSVETLLDILICLYDECNNSPLRREKNILEYLEWA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 MSGEVRLRQLEQFILDGPAQTNGQCFSVETLLDILICLYDECNNSPLRREKNILEYLEWA
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB3 KPFTSKVKQMRLHREDFEILKVIGRGAFGEVAVVKLKNADKVFAMKILNKWEMLKRAETA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 KPFTSKVKQMRLHREDFEILKVIGRGAFGEVAVVKLKNADKVFAMKILNKWEMLKRAETA
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB3 CFREERDVLVNGDNKWITTLHYAFQDDNNLYLVMDYYVGGDLLTLLSKFEDRLPEDMARF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 CFREERDVLVNGDNKWITTLHYAFQDDNNLYLVMDYYVGGDLLTLLSKFEDRLPEDMARF
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB3 YLAEMVIAIDSVHQLHYVHRDIKPDNILMDMNGHIRLADFGSCLKLMEDGTVQSSVAVGT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 YLAEMVIAIDSVHQLHYVHRDIKPDNILMDMNGHIRLADFGSCLKLMEDGTVQSSVAVGT
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB3 PDYISPEILQAMEDGKGRYGPECDWWSLGVCMYEMLYGETPFYAESLVETYGKIMNHKER
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 PDYISPEILQAMEDGKGRYGPECDWWSLGVCMYEMLYGETPFYAESLVETYGKIMNHKER
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KB3 FQFPAQVTDVSENAKDLIRRLICSREHRLGQNGIEDFKKHPFFSGIDWDNIRNCEAPYIP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 FQFPAQVTDVSENAKDLIRRLICSREHRLGQNGIEDFKKHPFFSGIDWDNIRNCEAPYIP
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KB3 EVSSPTDTSNFDVDDDCLKNSETMPPPTHTAFSGHHLPFVGFTYTSSCVLSDRSCLRVTA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 EVSSPTDTSNFDVDDDCLKNSETMPPPTHTAFSGHHLPFVGFTYTSSCVLSDRSCLRVTA
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KB3 GPTSLDLDVNVQRTLDNNLATEAYERRIKRLEQEKLELSRKLQESTQTVQALQYSTVDGP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 GPTSLDLDVNVQRTLDNNLATEAYERRIKRLEQEKLELSRKLQESTQTVQALQYSTVDGP
              430       440       450       460       470       480

              490       500       510       520       530       540
pF1KB3 LTASKDLEIKNLKEEIEKLRKQVTESSHLEQQLEEANAVRQELDDAFRQIKAYEKQIKTL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 LTASKDLEIKNLKEEIEKLRKQVTESSHLEQQLEEANAVRQELDDAFRQIKAYEKQIKTL
              490       500       510       520       530       540

              550       560       570       580       590       600
pF1KB3 QQEREDLNKELVQASERLKNQSKELKDAHCQRKLAMQEFMEINERLTELHTQKQKLARHV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 QQEREDLNKELVQASERLKNQSKELKDAHCQRKLAMQEFMEINERLTELHTQKQKLARHV
              550       560       570       580       590       600

              610       620       630       640       650       660
pF1KB3 RDKEEEVDLVMQKVESLRQELRRTERAKKELEVHTEALAAEASKDRKLREQSEHYSKQLE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 RDKEEEVDLVMQKVESLRQELRRTERAKKELEVHTEALAAEASKDRKLREQSEHYSKQLE
              610       620       630       640       650       660

              670       680       690       700       710       720
pF1KB3 NELEGLKQKQISYSPGVCSIEHQQEITKLKTDLEKKSIFYEEELSKREGIHANEIKNLKK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 NELEGLKQKQISYSPGVCSIEHQQEITKLKTDLEKKSIFYEEELSKREGIHANEIKNLKK
              670       680       690       700       710       720

              730       740       750       760       770       780
pF1KB3 ELHDSEGQQLALNKEIMILKDKLEKTRRESQSEREEFESEFKQQYEREKVLLTEENKKLT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 ELHDSEGQQLALNKEIMILKDKLEKTRRESQSEREEFESEFKQQYEREKVLLTEENKKLT
              730       740       750       760       770       780

              790       800       810       820       830       840
pF1KB3 SELDKLTTLYENLSIHNQQLEEEVKDLADKKESVAHWEAQITEIIQWVSDEKDARGYLQA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 SELDKLTTLYENLSIHNQQLEEEVKDLADKKESVAHWEAQITEIIQWVSDEKDARGYLQA
              790       800       810       820       830       840

              850       860       870       880       890       900
pF1KB3 LASKMTEELEALRNSSLGTRATDMPWKMRRFAKLDMSARLELQSALDAEIRAKQAIQEEL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 LASKMTEELEALRNSSLGTRATDMPWKMRRFAKLDMSARLELQSALDAEIRAKQAIQEEL
              850       860       870       880       890       900

              910       920       930       940       950       960
pF1KB3 NKVKASNIITECKLKDSEKKNLELLSEIEQLIKDTEELRSEKGIEHQDSQHSFLAFLNTP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 NKVKASNIITECKLKDSEKKNLELLSEIEQLIKDTEELRSEKGIEHQDSQHSFLAFLNTP
              910       920       930       940       950       960

                                          970       980       990  
pF1KB3 TDALDQFE----------------------------RKTHQFFVKSFTTPTKCHQCTSLM
       ::::::::                            ::::::::::::::::::::::::
NP_003 TDALDQFETVDSTPLSVHTPTLRKKGCPGSTGFPPKRKTHQFFVKSFTTPTKCHQCTSLM
              970       980       990      1000      1010      1020

           1000      1010      1020      1030      1040      1050  
pF1KB3 VGLIRQGCSCEVCGFSCHITCVNKAPTTCPVPPEQTKGPLGIDPQKGIGTAYEGHVRIPK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 VGLIRQGCSCEVCGFSCHITCVNKAPTTCPVPPEQTKGPLGIDPQKGIGTAYEGHVRIPK
             1030      1040      1050      1060      1070      1080

           1060      1070      1080      1090      1100      1110  
pF1KB3 PAGVKKGWQRALAIVCDFKLFLYDIAEGKASQPSVVISQVIDMRDEEFSVSSVLASDVIH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 PAGVKKGWQRALAIVCDFKLFLYDIAEGKASQPSVVISQVIDMRDEEFSVSSVLASDVIH
             1090      1100      1110      1120      1130      1140

           1120      1130      1140      1150      1160      1170  
pF1KB3 ASRKDIPCIFRVTASQLSASNNKCSILMLADTENEKNKWVGVLSELHKILKKNKFRDRSV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 ASRKDIPCIFRVTASQLSASNNKCSILMLADTENEKNKWVGVLSELHKILKKNKFRDRSV
             1150      1160      1170      1180      1190      1200

           1180      1190      1200      1210      1220      1230  
pF1KB3 YVPKEAYDSTLPLIKTTQAAAIIDHERIALGNEEGLFVVHVTKDEIIRVGDNKKIHQIEL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 YVPKEAYDSTLPLIKTTQAAAIIDHERIALGNEEGLFVVHVTKDEIIRVGDNKKIHQIEL
             1210      1220      1230      1240      1250      1260

           1240      1250      1260      1270      1280      1290  
pF1KB3 IPNDQLVAVISGRNRHVRLFPMSALDGRETDFYKLSETKGCQTVTSGKVRHGALTCLCVA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 IPNDQLVAVISGRNRHVRLFPMSALDGRETDFYKLSETKGCQTVTSGKVRHGALTCLCVA
             1270      1280      1290      1300      1310      1320

           1300      1310      1320      1330      1340      1350  
pF1KB3 MKRQVLCYELFQSKTRHRKFKEIQVPYNVQWMAIFSEQLCVGFQSGFLRYPLNGEGNPYS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 MKRQVLCYELFQSKTRHRKFKEIQVPYNVQWMAIFSEQLCVGFQSGFLRYPLNGEGNPYS
             1330      1340      1350      1360      1370      1380

           1360      1370      1380      1390      1400      1410  
pF1KB3 MLHSNDHTLSFIAHQPMDAICAVEISSKEYLLCFNSIGIYTDCQGRRSRQQELMWPANPS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 MLHSNDHTLSFIAHQPMDAICAVEISSKEYLLCFNSIGIYTDCQGRRSRQQELMWPANPS
             1390      1400      1410      1420      1430      1440

           1420      1430      1440      1450      1460      1470  
pF1KB3 SCCYNAPYLSVYSENAVDIFDVNSMEWIQTLPLKKVRPLNNEGSLNLLGLETIRLIYFKN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 SCCYNAPYLSVYSENAVDIFDVNSMEWIQTLPLKKVRPLNNEGSLNLLGLETIRLIYFKN
             1450      1460      1470      1480      1490      1500

           1480      1490      1500      1510      1520      1530  
pF1KB3 KMAEGDELVVPETSDNSRKQMVRNINNKRRYSFRVPEEERMQQRREMLRDPEMRNKLISN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 KMAEGDELVVPETSDNSRKQMVRNINNKRRYSFRVPEEERMQQRREMLRDPEMRNKLISN
             1510      1520      1530      1540      1550      1560

           1540      1550      1560      1570      1580      1590  
pF1KB3 PTNFNHIAHMGPGDGIQILKDLPMNPRPQESRTVFSGSVSIPSITKSRPEPGRSMSASSG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 PTNFNHIAHMGPGDGIQILKDLPMNPRPQESRTVFSGSVSIPSITKSRPEPGRSMSASSG
             1570      1580      1590      1600      1610      1620

           1600      1610      1620      1630      1640      1650  
pF1KB3 LSARSSAQNGSALKREFSGGSYSAKRQPMPSPSEGSLSSGGMDQGSDAPARDFDGEDSDS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 LSARSSAQNGSALKREFSGGSYSAKRQPMPSPSEGSLSSGGMDQGSDAPARDFDGEDSDS
             1630      1640      1650      1660      1670      1680

           1660      1670      1680      1690 
pF1KB3 PRHSTASNSSNLSSPPSPVSPRKTKSLSLESTDRGSWDP
       ::::::::::::::::::.::::::::::::::::::::
NP_003 PRHSTASNSSNLSSPPSPASPRKTKSLSLESTDRGSWDP
             1690      1700      1710         

>>XP_005273379 (OMIM: 603412) PREDICTED: serine/threonin  (1754 aa)
 initn: 6289 init1: 6289 opt: 6289  Z-score: 1906.0  bits: 365.7 E(85289): 2e-99
Smith-Waterman score: 10819; 96.3% identity (96.3% similar) in 1723 aa overlap (1-1660:1-1723)

               10        20        30        40        50        60
pF1KB3 MSGEVRLRQLEQFILDGPAQTNGQCFSVETLLDILICLYDECNNSPLRREKNILEYLEWA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MSGEVRLRQLEQFILDGPAQTNGQCFSVETLLDILICLYDECNNSPLRREKNILEYLEWA
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB3 KPFTSKVKQMRLHREDFEILKVIGRGAFGEVAVVKLKNADKVFAMKILNKWEMLKRAETA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 KPFTSKVKQMRLHREDFEILKVIGRGAFGEVAVVKLKNADKVFAMKILNKWEMLKRAETA
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB3 CFREERDVLVNGDNKWITTLHYAFQDDNNLYLVMDYYVGGDLLTLLSKFEDRLPEDMARF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 CFREERDVLVNGDNKWITTLHYAFQDDNNLYLVMDYYVGGDLLTLLSKFEDRLPEDMARF
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB3 YLAEMVIAIDSVHQLHYVHRDIKPDNILMDMNGHIRLADFGSCLKLMEDGTVQSSVAVGT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 YLAEMVIAIDSVHQLHYVHRDIKPDNILMDMNGHIRLADFGSCLKLMEDGTVQSSVAVGT
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB3 PDYISPEILQAMEDGKGRYGPECDWWSLGVCMYEMLYGETPFYAESLVETYGKIMNHKER
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 PDYISPEILQAMEDGKGRYGPECDWWSLGVCMYEMLYGETPFYAESLVETYGKIMNHKER
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KB3 FQFPAQVTDVSENAKDLIRRLICSREHRLGQNGIEDFKKHPFFSGIDWDNIRNCEAPYIP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 FQFPAQVTDVSENAKDLIRRLICSREHRLGQNGIEDFKKHPFFSGIDWDNIRNCEAPYIP
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KB3 EVSSPTDTSNFDVDDDCLKNSETMPPPTHTAFSGHHLPFVGFTYTSSCVLSDRSCLRVTA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 EVSSPTDTSNFDVDDDCLKNSETMPPPTHTAFSGHHLPFVGFTYTSSCVLSDRSCLRVTA
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KB3 GPTSLDLDVNVQRTLDNNLATEAYERRIKRLEQEKLELSRKLQESTQTVQALQYSTVDGP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 GPTSLDLDVNVQRTLDNNLATEAYERRIKRLEQEKLELSRKLQESTQTVQALQYSTVDGP
              430       440       450       460       470       480

              490       500       510       520       530       540
pF1KB3 LTASKDLEIKNLKEEIEKLRKQVTESSHLEQQLEEANAVRQELDDAFRQIKAYEKQIKTL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LTASKDLEIKNLKEEIEKLRKQVTESSHLEQQLEEANAVRQELDDAFRQIKAYEKQIKTL
              490       500       510       520       530       540

              550       560       570       580       590       600
pF1KB3 QQEREDLNKELVQASERLKNQSKELKDAHCQRKLAMQEFMEINERLTELHTQKQKLARHV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 QQEREDLNKELVQASERLKNQSKELKDAHCQRKLAMQEFMEINERLTELHTQKQKLARHV
              550       560       570       580       590       600

              610       620       630       640       650       660
pF1KB3 RDKEEEVDLVMQKVESLRQELRRTERAKKELEVHTEALAAEASKDRKLREQSEHYSKQLE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 RDKEEEVDLVMQKVESLRQELRRTERAKKELEVHTEALAAEASKDRKLREQSEHYSKQLE
              610       620       630       640       650       660

              670       680       690       700       710       720
pF1KB3 NELEGLKQKQISYSPGVCSIEHQQEITKLKTDLEKKSIFYEEELSKREGIHANEIKNLKK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 NELEGLKQKQISYSPGVCSIEHQQEITKLKTDLEKKSIFYEEELSKREGIHANEIKNLKK
              670       680       690       700       710       720

              730       740       750       760       770       780
pF1KB3 ELHDSEGQQLALNKEIMILKDKLEKTRRESQSEREEFESEFKQQYEREKVLLTEENKKLT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 ELHDSEGQQLALNKEIMILKDKLEKTRRESQSEREEFESEFKQQYEREKVLLTEENKKLT
              730       740       750       760       770       780

              790       800       810       820       830       840
pF1KB3 SELDKLTTLYENLSIHNQQLEEEVKDLADKKESVAHWEAQITEIIQWVSDEKDARGYLQA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SELDKLTTLYENLSIHNQQLEEEVKDLADKKESVAHWEAQITEIIQWVSDEKDARGYLQA
              790       800       810       820       830       840

              850       860       870       880       890       900
pF1KB3 LASKMTEELEALRNSSLGTRATDMPWKMRRFAKLDMSARLELQSALDAEIRAKQAIQEEL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LASKMTEELEALRNSSLGTRATDMPWKMRRFAKLDMSARLELQSALDAEIRAKQAIQEEL
              850       860       870       880       890       900

              910       920       930       940       950       960
pF1KB3 NKVKASNIITECKLKDSEKKNLELLSEIEQLIKDTEELRSEKGIEHQDSQHSFLAFLNTP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 NKVKASNIITECKLKDSEKKNLELLSEIEQLIKDTEELRSEKGIEHQDSQHSFLAFLNTP
              910       920       930       940       950       960

                                                                   
pF1KB3 TDALDQFE----------------------------------------------------
       ::::::::                                                    
XP_005 TDALDQFETDPVENTYVWNPSVKFHIQSRSTSPSTSSEAEPVKTVDSTPLSVHTPTLRKK
              970       980       990      1000      1010      1020

                 970       980       990      1000      1010       
pF1KB3 -----------RKTHQFFVKSFTTPTKCHQCTSLMVGLIRQGCSCEVCGFSCHITCVNKA
                  :::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 GCPGSTGFPPKRKTHQFFVKSFTTPTKCHQCTSLMVGLIRQGCSCEVCGFSCHITCVNKA
             1030      1040      1050      1060      1070      1080

      1020      1030      1040      1050      1060      1070       
pF1KB3 PTTCPVPPEQTKGPLGIDPQKGIGTAYEGHVRIPKPAGVKKGWQRALAIVCDFKLFLYDI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 PTTCPVPPEQTKGPLGIDPQKGIGTAYEGHVRIPKPAGVKKGWQRALAIVCDFKLFLYDI
             1090      1100      1110      1120      1130      1140

      1080      1090      1100      1110      1120      1130       
pF1KB3 AEGKASQPSVVISQVIDMRDEEFSVSSVLASDVIHASRKDIPCIFRVTASQLSASNNKCS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 AEGKASQPSVVISQVIDMRDEEFSVSSVLASDVIHASRKDIPCIFRVTASQLSASNNKCS
             1150      1160      1170      1180      1190      1200

      1140      1150      1160      1170      1180      1190       
pF1KB3 ILMLADTENEKNKWVGVLSELHKILKKNKFRDRSVYVPKEAYDSTLPLIKTTQAAAIIDH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 ILMLADTENEKNKWVGVLSELHKILKKNKFRDRSVYVPKEAYDSTLPLIKTTQAAAIIDH
             1210      1220      1230      1240      1250      1260

      1200      1210      1220      1230      1240      1250       
pF1KB3 ERIALGNEEGLFVVHVTKDEIIRVGDNKKIHQIELIPNDQLVAVISGRNRHVRLFPMSAL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 ERIALGNEEGLFVVHVTKDEIIRVGDNKKIHQIELIPNDQLVAVISGRNRHVRLFPMSAL
             1270      1280      1290      1300      1310      1320

      1260      1270      1280      1290      1300      1310       
pF1KB3 DGRETDFYKLSETKGCQTVTSGKVRHGALTCLCVAMKRQVLCYELFQSKTRHRKFKEIQV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 DGRETDFYKLSETKGCQTVTSGKVRHGALTCLCVAMKRQVLCYELFQSKTRHRKFKEIQV
             1330      1340      1350      1360      1370      1380

      1320      1330      1340      1350      1360      1370       
pF1KB3 PYNVQWMAIFSEQLCVGFQSGFLRYPLNGEGNPYSMLHSNDHTLSFIAHQPMDAICAVEI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 PYNVQWMAIFSEQLCVGFQSGFLRYPLNGEGNPYSMLHSNDHTLSFIAHQPMDAICAVEI
             1390      1400      1410      1420      1430      1440

      1380      1390      1400      1410      1420      1430       
pF1KB3 SSKEYLLCFNSIGIYTDCQGRRSRQQELMWPANPSSCCYNAPYLSVYSENAVDIFDVNSM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SSKEYLLCFNSIGIYTDCQGRRSRQQELMWPANPSSCCYNAPYLSVYSENAVDIFDVNSM
             1450      1460      1470      1480      1490      1500

      1440      1450      1460      1470      1480      1490       
pF1KB3 EWIQTLPLKKVRPLNNEGSLNLLGLETIRLIYFKNKMAEGDELVVPETSDNSRKQMVRNI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 EWIQTLPLKKVRPLNNEGSLNLLGLETIRLIYFKNKMAEGDELVVPETSDNSRKQMVRNI
             1510      1520      1530      1540      1550      1560

      1500      1510      1520      1530      1540      1550       
pF1KB3 NNKRRYSFRVPEEERMQQRREMLRDPEMRNKLISNPTNFNHIAHMGPGDGIQILKDLPMN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 NNKRRYSFRVPEEERMQQRREMLRDPEMRNKLISNPTNFNHIAHMGPGDGIQILKDLPMN
             1570      1580      1590      1600      1610      1620

      1560      1570      1580      1590      1600      1610       
pF1KB3 PRPQESRTVFSGSVSIPSITKSRPEPGRSMSASSGLSARSSAQNGSALKREFSGGSYSAK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 PRPQESRTVFSGSVSIPSITKSRPEPGRSMSASSGLSARSSAQNGSALKREFSGGSYSAK
             1630      1640      1650      1660      1670      1680

      1620      1630      1640      1650      1660      1670       
pF1KB3 RQPMPSPSEGSLSSGGMDQGSDAPARDFDGEDSDSPRHSTASNSSNLSSPPSPVSPRKTK
       :::::::::::::::::::::::::::::::::::::::::::                 
XP_005 RQPMPSPSEGSLSSGGMDQGSDAPARDFDGEDSDSPRHSTASNSSNLSSPPSPASPRKTK
             1690      1700      1710      1720      1730      1740

      1680      1690 
pF1KB3 SLSLESTDRGSWDP
                     
XP_005 SLSLESTDRGSWDP
             1750    

>>XP_005273378 (OMIM: 603412) PREDICTED: serine/threonin  (1781 aa)
 initn: 10279 init1: 6289 opt: 6289  Z-score: 1905.9  bits: 365.8 E(85289): 2e-99
Smith-Waterman score: 10567; 94.8% identity (94.8% similar) in 1723 aa overlap (1-1633:1-1723)

               10        20        30        40        50        60
pF1KB3 MSGEVRLRQLEQFILDGPAQTNGQCFSVETLLDILICLYDECNNSPLRREKNILEYLEWA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MSGEVRLRQLEQFILDGPAQTNGQCFSVETLLDILICLYDECNNSPLRREKNILEYLEWA
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB3 KPFTSKVKQMRLHREDFEILKVIGRGAFGEVAVVKLKNADKVFAMKILNKWEMLKRAETA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 KPFTSKVKQMRLHREDFEILKVIGRGAFGEVAVVKLKNADKVFAMKILNKWEMLKRAETA
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB3 CFREERDVLVNGDNKWITTLHYAFQDDNNLYLVMDYYVGGDLLTLLSKFEDRLPEDMARF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 CFREERDVLVNGDNKWITTLHYAFQDDNNLYLVMDYYVGGDLLTLLSKFEDRLPEDMARF
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB3 YLAEMVIAIDSVHQLHYVHRDIKPDNILMDMNGHIRLADFGSCLKLMEDGTVQSSVAVGT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 YLAEMVIAIDSVHQLHYVHRDIKPDNILMDMNGHIRLADFGSCLKLMEDGTVQSSVAVGT
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB3 PDYISPEILQAMEDGKGRYGPECDWWSLGVCMYEMLYGETPFYAESLVETYGKIMNHKER
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 PDYISPEILQAMEDGKGRYGPECDWWSLGVCMYEMLYGETPFYAESLVETYGKIMNHKER
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KB3 FQFPAQVTDVSENAKDLIRRLICSREHRLGQNGIEDFKKHPFFSGIDWDNIRNCEAPYIP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 FQFPAQVTDVSENAKDLIRRLICSREHRLGQNGIEDFKKHPFFSGIDWDNIRNCEAPYIP
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KB3 EVSSPTDTSNFDVDDDCLKNSETMPPPTHTAFSGHHLPFVGFTYTSSCVLSDRSCLRVTA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 EVSSPTDTSNFDVDDDCLKNSETMPPPTHTAFSGHHLPFVGFTYTSSCVLSDRSCLRVTA
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KB3 GPTSLDLDVNVQRTLDNNLATEAYERRIKRLEQEKLELSRKLQESTQTVQALQYSTVDGP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 GPTSLDLDVNVQRTLDNNLATEAYERRIKRLEQEKLELSRKLQESTQTVQALQYSTVDGP
              430       440       450       460       470       480

              490       500       510       520       530       540
pF1KB3 LTASKDLEIKNLKEEIEKLRKQVTESSHLEQQLEEANAVRQELDDAFRQIKAYEKQIKTL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LTASKDLEIKNLKEEIEKLRKQVTESSHLEQQLEEANAVRQELDDAFRQIKAYEKQIKTL
              490       500       510       520       530       540

              550       560       570       580       590       600
pF1KB3 QQEREDLNKELVQASERLKNQSKELKDAHCQRKLAMQEFMEINERLTELHTQKQKLARHV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 QQEREDLNKELVQASERLKNQSKELKDAHCQRKLAMQEFMEINERLTELHTQKQKLARHV
              550       560       570       580       590       600

              610       620       630       640       650       660
pF1KB3 RDKEEEVDLVMQKVESLRQELRRTERAKKELEVHTEALAAEASKDRKLREQSEHYSKQLE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 RDKEEEVDLVMQKVESLRQELRRTERAKKELEVHTEALAAEASKDRKLREQSEHYSKQLE
              610       620       630       640       650       660

              670       680       690       700       710       720
pF1KB3 NELEGLKQKQISYSPGVCSIEHQQEITKLKTDLEKKSIFYEEELSKREGIHANEIKNLKK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 NELEGLKQKQISYSPGVCSIEHQQEITKLKTDLEKKSIFYEEELSKREGIHANEIKNLKK
              670       680       690       700       710       720

              730       740       750       760       770       780
pF1KB3 ELHDSEGQQLALNKEIMILKDKLEKTRRESQSEREEFESEFKQQYEREKVLLTEENKKLT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 ELHDSEGQQLALNKEIMILKDKLEKTRRESQSEREEFESEFKQQYEREKVLLTEENKKLT
              730       740       750       760       770       780

              790       800       810       820       830       840
pF1KB3 SELDKLTTLYENLSIHNQQLEEEVKDLADKKESVAHWEAQITEIIQWVSDEKDARGYLQA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SELDKLTTLYENLSIHNQQLEEEVKDLADKKESVAHWEAQITEIIQWVSDEKDARGYLQA
              790       800       810       820       830       840

              850       860       870       880       890       900
pF1KB3 LASKMTEELEALRNSSLGTRATDMPWKMRRFAKLDMSARLELQSALDAEIRAKQAIQEEL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LASKMTEELEALRNSSLGTRATDMPWKMRRFAKLDMSARLELQSALDAEIRAKQAIQEEL
              850       860       870       880       890       900

              910       920       930       940       950       960
pF1KB3 NKVKASNIITECKLKDSEKKNLELLSEIEQLIKDTEELRSEKGIEHQDSQHSFLAFLNTP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 NKVKASNIITECKLKDSEKKNLELLSEIEQLIKDTEELRSEKGIEHQDSQHSFLAFLNTP
              910       920       930       940       950       960

                                          970       980       990  
pF1KB3 TDALDQFE----------------------------RKTHQFFVKSFTTPTKCHQCTSLM
       ::::::::                            ::::::::::::::::::::::::
XP_005 TDALDQFETVDSTPLSVHTPTLRKKGCPGSTGFPPKRKTHQFFVKSFTTPTKCHQCTSLM
              970       980       990      1000      1010      1020

           1000      1010      1020      1030      1040      1050  
pF1KB3 VGLIRQGCSCEVCGFSCHITCVNKAPTTCPVPPEQTKGPLGIDPQKGIGTAYEGHVRIPK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 VGLIRQGCSCEVCGFSCHITCVNKAPTTCPVPPEQTKGPLGIDPQKGIGTAYEGHVRIPK
             1030      1040      1050      1060      1070      1080

           1060      1070      1080      1090      1100      1110  
pF1KB3 PAGVKKGWQRALAIVCDFKLFLYDIAEGKASQPSVVISQVIDMRDEEFSVSSVLASDVIH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 PAGVKKGWQRALAIVCDFKLFLYDIAEGKASQPSVVISQVIDMRDEEFSVSSVLASDVIH
             1090      1100      1110      1120      1130      1140

           1120      1130      1140      1150      1160      1170  
pF1KB3 ASRKDIPCIFRVTASQLSASNNKCSILMLADTENEKNKWVGVLSELHKILKKNKFRDRSV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 ASRKDIPCIFRVTASQLSASNNKCSILMLADTENEKNKWVGVLSELHKILKKNKFRDRSV
             1150      1160      1170      1180      1190      1200

           1180      1190      1200      1210      1220      1230  
pF1KB3 YVPKEAYDSTLPLIKTTQAAAIIDHERIALGNEEGLFVVHVTKDEIIRVGDNKKIHQIEL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 YVPKEAYDSTLPLIKTTQAAAIIDHERIALGNEEGLFVVHVTKDEIIRVGDNKKIHQIEL
             1210      1220      1230      1240      1250      1260

           1240      1250      1260      1270      1280      1290  
pF1KB3 IPNDQLVAVISGRNRHVRLFPMSALDGRETDFYKLSETKGCQTVTSGKVRHGALTCLCVA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 IPNDQLVAVISGRNRHVRLFPMSALDGRETDFYKLSETKGCQTVTSGKVRHGALTCLCVA
             1270      1280      1290      1300      1310      1320

           1300      1310      1320      1330      1340      1350  
pF1KB3 MKRQVLCYELFQSKTRHRKFKEIQVPYNVQWMAIFSEQLCVGFQSGFLRYPLNGEGNPYS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MKRQVLCYELFQSKTRHRKFKEIQVPYNVQWMAIFSEQLCVGFQSGFLRYPLNGEGNPYS
             1330      1340      1350      1360      1370      1380

           1360      1370      1380      1390      1400      1410  
pF1KB3 MLHSNDHTLSFIAHQPMDAICAVEISSKEYLLCFNSIGIYTDCQGRRSRQQELMWPANPS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MLHSNDHTLSFIAHQPMDAICAVEISSKEYLLCFNSIGIYTDCQGRRSRQQELMWPANPS
             1390      1400      1410      1420      1430      1440

           1420      1430      1440      1450      1460      1470  
pF1KB3 SCCYNAPYLSVYSENAVDIFDVNSMEWIQTLPLKKVRPLNNEGSLNLLGLETIRLIYFKN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SCCYNAPYLSVYSENAVDIFDVNSMEWIQTLPLKKVRPLNNEGSLNLLGLETIRLIYFKN
             1450      1460      1470      1480      1490      1500

           1480      1490      1500      1510      1520      1530  
pF1KB3 KMAEGDELVVPETSDNSRKQMVRNINNKRRYSFRVPEEERMQQRREMLRDPEMRNKLISN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 KMAEGDELVVPETSDNSRKQMVRNINNKRRYSFRVPEEERMQQRREMLRDPEMRNKLISN
             1510      1520      1530      1540      1550      1560

           1540      1550                                          
pF1KB3 PTNFNHIAHMGPGDGIQILKDLPM------------------------------------
       ::::::::::::::::::::::::                                    
XP_005 PTNFNHIAHMGPGDGIQILKDLPMPGFPYPSPHHHSGLISSPINFEHIYHMTVNSAEKFL
             1570      1580      1590      1600      1610      1620

                                 1560      1570      1580      1590
pF1KB3 --------------------------NPRPQESRTVFSGSVSIPSITKSRPEPGRSMSAS
                                 ::::::::::::::::::::::::::::::::::
XP_005 SPDSINPEYSPSLRSVPGTPSFMTLRNPRPQESRTVFSGSVSIPSITKSRPEPGRSMSAS
             1630      1640      1650      1660      1670      1680

             1600      1610      1620      1630      1640      1650
pF1KB3 SGLSARSSAQNGSALKREFSGGSYSAKRQPMPSPSEGSLSSGGMDQGSDAPARDFDGEDS
       :::::::::::::::::::::::::::::::::::::::::::                 
XP_005 SGLSARSSAQNGSALKREFSGGSYSAKRQPMPSPSEGSLSSGGMDQGSDAPARDFDGEDS
             1690      1700      1710      1720      1730      1740

             1660      1670      1680      1690 
pF1KB3 DSPRHSTASNSSNLSSPPSPVSPRKTKSLSLESTDRGSWDP
                                                
XP_005 DSPRHSTASNSSNLSSPPSPASPRKTKSLSLESTDRGSWDP
             1750      1760      1770      1780 

>>XP_011542610 (OMIM: 603412) PREDICTED: serine/threonin  (1783 aa)
 initn: 6289 init1: 6289 opt: 6289  Z-score: 1905.9  bits: 365.8 E(85289): 2e-99
Smith-Waterman score: 10557; 94.7% identity (94.7% similar) in 1723 aa overlap (1-1631:1-1723)

               10        20        30        40        50        60
pF1KB3 MSGEVRLRQLEQFILDGPAQTNGQCFSVETLLDILICLYDECNNSPLRREKNILEYLEWA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MSGEVRLRQLEQFILDGPAQTNGQCFSVETLLDILICLYDECNNSPLRREKNILEYLEWA
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB3 KPFTSKVKQMRLHREDFEILKVIGRGAFGEVAVVKLKNADKVFAMKILNKWEMLKRAETA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KPFTSKVKQMRLHREDFEILKVIGRGAFGEVAVVKLKNADKVFAMKILNKWEMLKRAETA
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB3 CFREERDVLVNGDNKWITTLHYAFQDDNNLYLVMDYYVGGDLLTLLSKFEDRLPEDMARF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 CFREERDVLVNGDNKWITTLHYAFQDDNNLYLVMDYYVGGDLLTLLSKFEDRLPEDMARF
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB3 YLAEMVIAIDSVHQLHYVHRDIKPDNILMDMNGHIRLADFGSCLKLMEDGTVQSSVAVGT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 YLAEMVIAIDSVHQLHYVHRDIKPDNILMDMNGHIRLADFGSCLKLMEDGTVQSSVAVGT
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB3 PDYISPEILQAMEDGKGRYGPECDWWSLGVCMYEMLYGETPFYAESLVETYGKIMNHKER
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PDYISPEILQAMEDGKGRYGPECDWWSLGVCMYEMLYGETPFYAESLVETYGKIMNHKER
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KB3 FQFPAQVTDVSENAKDLIRRLICSREHRLGQNGIEDFKKHPFFSGIDWDNIRNCEAPYIP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FQFPAQVTDVSENAKDLIRRLICSREHRLGQNGIEDFKKHPFFSGIDWDNIRNCEAPYIP
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KB3 EVSSPTDTSNFDVDDDCLKNSETMPPPTHTAFSGHHLPFVGFTYTSSCVLSDRSCLRVTA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EVSSPTDTSNFDVDDDCLKNSETMPPPTHTAFSGHHLPFVGFTYTSSCVLSDRSCLRVTA
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KB3 GPTSLDLDVNVQRTLDNNLATEAYERRIKRLEQEKLELSRKLQESTQTVQALQYSTVDGP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GPTSLDLDVNVQRTLDNNLATEAYERRIKRLEQEKLELSRKLQESTQTVQALQYSTVDGP
              430       440       450       460       470       480

              490       500       510       520       530       540
pF1KB3 LTASKDLEIKNLKEEIEKLRKQVTESSHLEQQLEEANAVRQELDDAFRQIKAYEKQIKTL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LTASKDLEIKNLKEEIEKLRKQVTESSHLEQQLEEANAVRQELDDAFRQIKAYEKQIKTL
              490       500       510       520       530       540

              550       560       570       580       590       600
pF1KB3 QQEREDLNKELVQASERLKNQSKELKDAHCQRKLAMQEFMEINERLTELHTQKQKLARHV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QQEREDLNKELVQASERLKNQSKELKDAHCQRKLAMQEFMEINERLTELHTQKQKLARHV
              550       560       570       580       590       600

              610       620       630       640       650       660
pF1KB3 RDKEEEVDLVMQKVESLRQELRRTERAKKELEVHTEALAAEASKDRKLREQSEHYSKQLE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RDKEEEVDLVMQKVESLRQELRRTERAKKELEVHTEALAAEASKDRKLREQSEHYSKQLE
              610       620       630       640       650       660

              670       680       690       700       710       720
pF1KB3 NELEGLKQKQISYSPGVCSIEHQQEITKLKTDLEKKSIFYEEELSKREGIHANEIKNLKK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NELEGLKQKQISYSPGVCSIEHQQEITKLKTDLEKKSIFYEEELSKREGIHANEIKNLKK
              670       680       690       700       710       720

              730       740       750       760       770       780
pF1KB3 ELHDSEGQQLALNKEIMILKDKLEKTRRESQSEREEFESEFKQQYEREKVLLTEENKKLT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ELHDSEGQQLALNKEIMILKDKLEKTRRESQSEREEFESEFKQQYEREKVLLTEENKKLT
              730       740       750       760       770       780

              790       800       810       820       830       840
pF1KB3 SELDKLTTLYENLSIHNQQLEEEVKDLADKKESVAHWEAQITEIIQWVSDEKDARGYLQA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SELDKLTTLYENLSIHNQQLEEEVKDLADKKESVAHWEAQITEIIQWVSDEKDARGYLQA
              790       800       810       820       830       840

              850       860       870       880       890       900
pF1KB3 LASKMTEELEALRNSSLGTRATDMPWKMRRFAKLDMSARLELQSALDAEIRAKQAIQEEL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LASKMTEELEALRNSSLGTRATDMPWKMRRFAKLDMSARLELQSALDAEIRAKQAIQEEL
              850       860       870       880       890       900

              910       920       930       940       950       960
pF1KB3 NKVKASNIITECKLKDSEKKNLELLSEIEQLIKDTEELRSEKGIEHQDSQHSFLAFLNTP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NKVKASNIITECKLKDSEKKNLELLSEIEQLIKDTEELRSEKGIEHQDSQHSFLAFLNTP
              910       920       930       940       950       960

                                                                   
pF1KB3 TDALDQFE----------------------------------------------------
       ::::::::                                                    
XP_011 TDALDQFEDSFSSSSSSLIDFLDDRSPSCTPASKGRRTDPVENTYVWNPSVKFHIQSRST
              970       980       990      1000      1010      1020

                                              970       980        
pF1KB3 ----------------------------------------RKTHQFFVKSFTTPTKCHQC
                                               ::::::::::::::::::::
XP_011 SPSTSSEAEPVKTVDSTPLSVHTPTLRKKGCPGSTGFPPKRKTHQFFVKSFTTPTKCHQC
             1030      1040      1050      1060      1070      1080

      990      1000      1010      1020      1030      1040        
pF1KB3 TSLMVGLIRQGCSCEVCGFSCHITCVNKAPTTCPVPPEQTKGPLGIDPQKGIGTAYEGHV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TSLMVGLIRQGCSCEVCGFSCHITCVNKAPTTCPVPPEQTKGPLGIDPQKGIGTAYEGHV
             1090      1100      1110      1120      1130      1140

     1050      1060      1070      1080      1090      1100        
pF1KB3 RIPKPAGVKKGWQRALAIVCDFKLFLYDIAEGKASQPSVVISQVIDMRDEEFSVSSVLAS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RIPKPAGVKKGWQRALAIVCDFKLFLYDIAEGKASQPSVVISQVIDMRDEEFSVSSVLAS
             1150      1160      1170      1180      1190      1200

     1110      1120      1130      1140      1150      1160        
pF1KB3 DVIHASRKDIPCIFRVTASQLSASNNKCSILMLADTENEKNKWVGVLSELHKILKKNKFR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DVIHASRKDIPCIFRVTASQLSASNNKCSILMLADTENEKNKWVGVLSELHKILKKNKFR
             1210      1220      1230      1240      1250      1260

     1170      1180      1190      1200      1210      1220        
pF1KB3 DRSVYVPKEAYDSTLPLIKTTQAAAIIDHERIALGNEEGLFVVHVTKDEIIRVGDNKKIH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DRSVYVPKEAYDSTLPLIKTTQAAAIIDHERIALGNEEGLFVVHVTKDEIIRVGDNKKIH
             1270      1280      1290      1300      1310      1320

     1230      1240      1250      1260      1270      1280        
pF1KB3 QIELIPNDQLVAVISGRNRHVRLFPMSALDGRETDFYKLSETKGCQTVTSGKVRHGALTC
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QIELIPNDQLVAVISGRNRHVRLFPMSALDGRETDFYKLSETKGCQTVTSGKVRHGALTC
             1330      1340      1350      1360      1370      1380

     1290      1300      1310      1320      1330      1340        
pF1KB3 LCVAMKRQVLCYELFQSKTRHRKFKEIQVPYNVQWMAIFSEQLCVGFQSGFLRYPLNGEG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LCVAMKRQVLCYELFQSKTRHRKFKEIQVPYNVQWMAIFSEQLCVGFQSGFLRYPLNGEG
             1390      1400      1410      1420      1430      1440

     1350      1360      1370      1380      1390      1400        
pF1KB3 NPYSMLHSNDHTLSFIAHQPMDAICAVEISSKEYLLCFNSIGIYTDCQGRRSRQQELMWP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NPYSMLHSNDHTLSFIAHQPMDAICAVEISSKEYLLCFNSIGIYTDCQGRRSRQQELMWP
             1450      1460      1470      1480      1490      1500

     1410      1420      1430      1440      1450      1460        
pF1KB3 ANPSSCCYNAPYLSVYSENAVDIFDVNSMEWIQTLPLKKVRPLNNEGSLNLLGLETIRLI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ANPSSCCYNAPYLSVYSENAVDIFDVNSMEWIQTLPLKKVRPLNNEGSLNLLGLETIRLI
             1510      1520      1530      1540      1550      1560

     1470      1480      1490      1500      1510      1520        
pF1KB3 YFKNKMAEGDELVVPETSDNSRKQMVRNINNKRRYSFRVPEEERMQQRREMLRDPEMRNK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 YFKNKMAEGDELVVPETSDNSRKQMVRNINNKRRYSFRVPEEERMQQRREMLRDPEMRNK
             1570      1580      1590      1600      1610      1620

     1530      1540      1550      1560      1570      1580        
pF1KB3 LISNPTNFNHIAHMGPGDGIQILKDLPMNPRPQESRTVFSGSVSIPSITKSRPEPGRSMS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LISNPTNFNHIAHMGPGDGIQILKDLPMNPRPQESRTVFSGSVSIPSITKSRPEPGRSMS
             1630      1640      1650      1660      1670      1680

     1590      1600      1610      1620      1630      1640        
pF1KB3 ASSGLSARSSAQNGSALKREFSGGSYSAKRQPMPSPSEGSLSSGGMDQGSDAPARDFDGE
       :::::::::::::::::::::::::::::::::::::::::::                 
XP_011 ASSGLSARSSAQNGSALKREFSGGSYSAKRQPMPSPSEGSLSSGGMDQGSDAPARDFDGE
             1690      1700      1710      1720      1730      1740

     1650      1660      1670      1680      1690 
pF1KB3 DSDSPRHSTASNSSNLSSPPSPVSPRKTKSLSLESTDRGSWDP
                                                  
XP_011 DSDSPRHSTASNSSNLSSPPSPASPRKTKSLSLESTDRGSWDP
             1750      1760      1770      1780   

>>XP_006711898 (OMIM: 603412) PREDICTED: serine/threonin  (1797 aa)
 initn: 10279 init1: 6289 opt: 6289  Z-score: 1905.8  bits: 365.8 E(85289): 2e-99
Smith-Waterman score: 10424; 93.8% identity (93.8% similar) in 1723 aa overlap (1-1617:1-1723)

               10        20        30        40        50        60
pF1KB3 MSGEVRLRQLEQFILDGPAQTNGQCFSVETLLDILICLYDECNNSPLRREKNILEYLEWA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 MSGEVRLRQLEQFILDGPAQTNGQCFSVETLLDILICLYDECNNSPLRREKNILEYLEWA
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB3 KPFTSKVKQMRLHREDFEILKVIGRGAFGEVAVVKLKNADKVFAMKILNKWEMLKRAETA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 KPFTSKVKQMRLHREDFEILKVIGRGAFGEVAVVKLKNADKVFAMKILNKWEMLKRAETA
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB3 CFREERDVLVNGDNKWITTLHYAFQDDNNLYLVMDYYVGGDLLTLLSKFEDRLPEDMARF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 CFREERDVLVNGDNKWITTLHYAFQDDNNLYLVMDYYVGGDLLTLLSKFEDRLPEDMARF
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB3 YLAEMVIAIDSVHQLHYVHRDIKPDNILMDMNGHIRLADFGSCLKLMEDGTVQSSVAVGT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 YLAEMVIAIDSVHQLHYVHRDIKPDNILMDMNGHIRLADFGSCLKLMEDGTVQSSVAVGT
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB3 PDYISPEILQAMEDGKGRYGPECDWWSLGVCMYEMLYGETPFYAESLVETYGKIMNHKER
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 PDYISPEILQAMEDGKGRYGPECDWWSLGVCMYEMLYGETPFYAESLVETYGKIMNHKER
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KB3 FQFPAQVTDVSENAKDLIRRLICSREHRLGQNGIEDFKKHPFFSGIDWDNIRNCEAPYIP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 FQFPAQVTDVSENAKDLIRRLICSREHRLGQNGIEDFKKHPFFSGIDWDNIRNCEAPYIP
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KB3 EVSSPTDTSNFDVDDDCLKNSETMPPPTHTAFSGHHLPFVGFTYTSSCVLSDRSCLRVTA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 EVSSPTDTSNFDVDDDCLKNSETMPPPTHTAFSGHHLPFVGFTYTSSCVLSDRSCLRVTA
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KB3 GPTSLDLDVNVQRTLDNNLATEAYERRIKRLEQEKLELSRKLQESTQTVQALQYSTVDGP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 GPTSLDLDVNVQRTLDNNLATEAYERRIKRLEQEKLELSRKLQESTQTVQALQYSTVDGP
              430       440       450       460       470       480

              490       500       510       520       530       540
pF1KB3 LTASKDLEIKNLKEEIEKLRKQVTESSHLEQQLEEANAVRQELDDAFRQIKAYEKQIKTL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 LTASKDLEIKNLKEEIEKLRKQVTESSHLEQQLEEANAVRQELDDAFRQIKAYEKQIKTL
              490       500       510       520       530       540

              550       560       570       580       590       600
pF1KB3 QQEREDLNKELVQASERLKNQSKELKDAHCQRKLAMQEFMEINERLTELHTQKQKLARHV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 QQEREDLNKELVQASERLKNQSKELKDAHCQRKLAMQEFMEINERLTELHTQKQKLARHV
              550       560       570       580       590       600

              610       620       630       640       650       660
pF1KB3 RDKEEEVDLVMQKVESLRQELRRTERAKKELEVHTEALAAEASKDRKLREQSEHYSKQLE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 RDKEEEVDLVMQKVESLRQELRRTERAKKELEVHTEALAAEASKDRKLREQSEHYSKQLE
              610       620       630       640       650       660

              670       680       690       700       710       720
pF1KB3 NELEGLKQKQISYSPGVCSIEHQQEITKLKTDLEKKSIFYEEELSKREGIHANEIKNLKK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 NELEGLKQKQISYSPGVCSIEHQQEITKLKTDLEKKSIFYEEELSKREGIHANEIKNLKK
              670       680       690       700       710       720

              730       740       750       760       770       780
pF1KB3 ELHDSEGQQLALNKEIMILKDKLEKTRRESQSEREEFESEFKQQYEREKVLLTEENKKLT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 ELHDSEGQQLALNKEIMILKDKLEKTRRESQSEREEFESEFKQQYEREKVLLTEENKKLT
              730       740       750       760       770       780

              790       800       810       820       830       840
pF1KB3 SELDKLTTLYENLSIHNQQLEEEVKDLADKKESVAHWEAQITEIIQWVSDEKDARGYLQA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 SELDKLTTLYENLSIHNQQLEEEVKDLADKKESVAHWEAQITEIIQWVSDEKDARGYLQA
              790       800       810       820       830       840

              850       860       870       880       890       900
pF1KB3 LASKMTEELEALRNSSLGTRATDMPWKMRRFAKLDMSARLELQSALDAEIRAKQAIQEEL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 LASKMTEELEALRNSSLGTRATDMPWKMRRFAKLDMSARLELQSALDAEIRAKQAIQEEL
              850       860       870       880       890       900

              910       920       930       940       950       960
pF1KB3 NKVKASNIITECKLKDSEKKNLELLSEIEQLIKDTEELRSEKGIEHQDSQHSFLAFLNTP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 NKVKASNIITECKLKDSEKKNLELLSEIEQLIKDTEELRSEKGIEHQDSQHSFLAFLNTP
              910       920       930       940       950       960

                                                          970      
pF1KB3 TDALDQFE--------------------------------------------RKTHQFFV
       ::::::::                                            ::::::::
XP_006 TDALDQFEDSFSSSSSSLIDFLDDTVDSTPLSVHTPTLRKKGCPGSTGFPPKRKTHQFFV
              970       980       990      1000      1010      1020

        980       990      1000      1010      1020      1030      
pF1KB3 KSFTTPTKCHQCTSLMVGLIRQGCSCEVCGFSCHITCVNKAPTTCPVPPEQTKGPLGIDP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 KSFTTPTKCHQCTSLMVGLIRQGCSCEVCGFSCHITCVNKAPTTCPVPPEQTKGPLGIDP
             1030      1040      1050      1060      1070      1080

       1040      1050      1060      1070      1080      1090      
pF1KB3 QKGIGTAYEGHVRIPKPAGVKKGWQRALAIVCDFKLFLYDIAEGKASQPSVVISQVIDMR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 QKGIGTAYEGHVRIPKPAGVKKGWQRALAIVCDFKLFLYDIAEGKASQPSVVISQVIDMR
             1090      1100      1110      1120      1130      1140

       1100      1110      1120      1130      1140      1150      
pF1KB3 DEEFSVSSVLASDVIHASRKDIPCIFRVTASQLSASNNKCSILMLADTENEKNKWVGVLS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 DEEFSVSSVLASDVIHASRKDIPCIFRVTASQLSASNNKCSILMLADTENEKNKWVGVLS
             1150      1160      1170      1180      1190      1200

       1160      1170      1180      1190      1200      1210      
pF1KB3 ELHKILKKNKFRDRSVYVPKEAYDSTLPLIKTTQAAAIIDHERIALGNEEGLFVVHVTKD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 ELHKILKKNKFRDRSVYVPKEAYDSTLPLIKTTQAAAIIDHERIALGNEEGLFVVHVTKD
             1210      1220      1230      1240      1250      1260

       1220      1230      1240      1250      1260      1270      
pF1KB3 EIIRVGDNKKIHQIELIPNDQLVAVISGRNRHVRLFPMSALDGRETDFYKLSETKGCQTV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 EIIRVGDNKKIHQIELIPNDQLVAVISGRNRHVRLFPMSALDGRETDFYKLSETKGCQTV
             1270      1280      1290      1300      1310      1320

       1280      1290      1300      1310      1320      1330      
pF1KB3 TSGKVRHGALTCLCVAMKRQVLCYELFQSKTRHRKFKEIQVPYNVQWMAIFSEQLCVGFQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 TSGKVRHGALTCLCVAMKRQVLCYELFQSKTRHRKFKEIQVPYNVQWMAIFSEQLCVGFQ
             1330      1340      1350      1360      1370      1380

       1340      1350      1360      1370      1380      1390      
pF1KB3 SGFLRYPLNGEGNPYSMLHSNDHTLSFIAHQPMDAICAVEISSKEYLLCFNSIGIYTDCQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 SGFLRYPLNGEGNPYSMLHSNDHTLSFIAHQPMDAICAVEISSKEYLLCFNSIGIYTDCQ
             1390      1400      1410      1420      1430      1440

       1400      1410      1420      1430      1440      1450      
pF1KB3 GRRSRQQELMWPANPSSCCYNAPYLSVYSENAVDIFDVNSMEWIQTLPLKKVRPLNNEGS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 GRRSRQQELMWPANPSSCCYNAPYLSVYSENAVDIFDVNSMEWIQTLPLKKVRPLNNEGS
             1450      1460      1470      1480      1490      1500

       1460      1470      1480      1490      1500      1510      
pF1KB3 LNLLGLETIRLIYFKNKMAEGDELVVPETSDNSRKQMVRNINNKRRYSFRVPEEERMQQR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 LNLLGLETIRLIYFKNKMAEGDELVVPETSDNSRKQMVRNINNKRRYSFRVPEEERMQQR
             1510      1520      1530      1540      1550      1560

       1520      1530      1540      1550                          
pF1KB3 REMLRDPEMRNKLISNPTNFNHIAHMGPGDGIQILKDLPM--------------------
       ::::::::::::::::::::::::::::::::::::::::                    
XP_006 REMLRDPEMRNKLISNPTNFNHIAHMGPGDGIQILKDLPMPGFPYPSPHHHSGLISSPIN
             1570      1580      1590      1600      1610      1620

                                                 1560      1570    
pF1KB3 ------------------------------------------NPRPQESRTVFSGSVSIP
                                                 ::::::::::::::::::
XP_006 FEHIYHMTVNSAEKFLSPDSINPEYSPSLRSVPGTPSFMTLRNPRPQESRTVFSGSVSIP
             1630      1640      1650      1660      1670      1680

         1580      1590      1600      1610      1620      1630    
pF1KB3 SITKSRPEPGRSMSASSGLSARSSAQNGSALKREFSGGSYSAKRQPMPSPSEGSLSSGGM
       :::::::::::::::::::::::::::::::::::::::::::                 
XP_006 SITKSRPEPGRSMSASSGLSARSSAQNGSALKREFSGGSYSAKRQPMPSPSEGSLSSGGM
             1690      1700      1710      1720      1730      1740

         1640      1650      1660      1670      1680      1690 
pF1KB3 DQGSDAPARDFDGEDSDSPRHSTASNSSNLSSPPSPVSPRKTKSLSLESTDRGSWDP
                                                                
XP_006 DQGSDAPARDFDGEDSDSPRHSTASNSSNLSSPPSPASPRKTKSLSLESTDRGSWDP
             1750      1760      1770      1780      1790       




1691 residues in 1 query   sequences
60827320 residues in 85289 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Thu Nov  3 13:01:41 2016 done: Thu Nov  3 13:01:43 2016
 Total Scan time: 17.950 Total Display time:  1.070

Function used was FASTA [36.3.4 Apr, 2011]
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