Result of FASTA (omim) for pF1KB3098
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KB3098, 646 aa
  1>>>pF1KB3098 646 - 646 aa - 646 aa
Library: /omim/omim.rfq.tfa
  60827320 residues in 85289 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 10.6980+/-0.000421; mu= -1.7232+/- 0.026
 mean_var=544.4985+/-120.461, 0's: 0 Z-trim(123.3): 49  B-trim: 33 in 1/57
 Lambda= 0.054964
 statistics sampled from 42812 (42892) to 42812 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.787), E-opt: 0.2 (0.503), width:  16
 Scan time: 13.540

The best scores are:                                      opt bits E(85289)
NP_003381 (OMIM: 193525) wee1-like protein kinase  ( 646) 4352 360.2 1.3e-98
NP_001137448 (OMIM: 193525) wee1-like protein kina ( 432) 2830 239.3 2.2e-62
NP_001099028 (OMIM: 614084) wee1-like protein kina ( 567) 1400 126.1 3.5e-28


>>NP_003381 (OMIM: 193525) wee1-like protein kinase isof  (646 aa)
 initn: 4352 init1: 4352 opt: 4352  Z-score: 1891.5  bits: 360.2 E(85289): 1.3e-98
Smith-Waterman score: 4352; 100.0% identity (100.0% similar) in 646 aa overlap (1-646:1-646)

               10        20        30        40        50        60
pF1KB3 MSFLSRQQPPPPRRAGAACTLRQKLIFSPCSDCEEEEEEEEEEGSGHSTGEDSAFQEPDS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 MSFLSRQQPPPPRRAGAACTLRQKLIFSPCSDCEEEEEEEEEEGSGHSTGEDSAFQEPDS
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB3 PLPPARSPTEPGPERRRSPGPAPGSPGELEEDLLLPGACPGADEAGGGAEGDSWEEEGFG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 PLPPARSPTEPGPERRRSPGPAPGSPGELEEDLLLPGACPGADEAGGGAEGDSWEEEGFG
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB3 SSSPVKSPAAPYFLGSSFSPVRCGGPGDASPRGCGARRAGEGRRSPRPDHPGTPPHKTFR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 SSSPVKSPAAPYFLGSSFSPVRCGGPGDASPRGCGARRAGEGRRSPRPDHPGTPPHKTFR
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB3 KLRLFDTPHTPKSLLSKARGIDSSSVKLRGSSLFMDTEKSGKREFDVRQTPQVNINPFTP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 KLRLFDTPHTPKSLLSKARGIDSSSVKLRGSSLFMDTEKSGKREFDVRQTPQVNINPFTP
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB3 DSLLLHSSGQCRRRKRTYWNDSCGEDMEASDYELEDETRPAKRITITESNMKSRYTTEFH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 DSLLLHSSGQCRRRKRTYWNDSCGEDMEASDYELEDETRPAKRITITESNMKSRYTTEFH
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KB3 ELEKIGSGEFGSVFKCVKRLDGCIYAIKRSKKPLAGSVDEQNALREVYAHAVLGQHSHVV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 ELEKIGSGEFGSVFKCVKRLDGCIYAIKRSKKPLAGSVDEQNALREVYAHAVLGQHSHVV
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KB3 RYFSAWAEDDHMLIQNEYCNGGSLADAISENYRIMSYFKEAELKDLLLQVGRGLRYIHSM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 RYFSAWAEDDHMLIQNEYCNGGSLADAISENYRIMSYFKEAELKDLLLQVGRGLRYIHSM
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KB3 SLVHMDIKPSNIFISRTSIPNAASEEGDEDDWASNKVMFKIGDLGHVTRISSPQVEEGDS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 SLVHMDIKPSNIFISRTSIPNAASEEGDEDDWASNKVMFKIGDLGHVTRISSPQVEEGDS
              430       440       450       460       470       480

              490       500       510       520       530       540
pF1KB3 RFLANEVLQENYTHLPKADIFALALTVVCAAGAEPLPRNGDQWHEIRQGRLPRIPQVLSQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 RFLANEVLQENYTHLPKADIFALALTVVCAAGAEPLPRNGDQWHEIRQGRLPRIPQVLSQ
              490       500       510       520       530       540

              550       560       570       580       590       600
pF1KB3 EFTELLKVMIHPDPERRPSAMALVKHSVLLSASRKSAEQLRIELNAEKFKNSLLQKELKK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 EFTELLKVMIHPDPERRPSAMALVKHSVLLSASRKSAEQLRIELNAEKFKNSLLQKELKK
              550       560       570       580       590       600

              610       620       630       640      
pF1KB3 AQMAKAAAEERALFTDRMATRSTTQSNRTSRLIGKKMNRSVSLTIY
       ::::::::::::::::::::::::::::::::::::::::::::::
NP_003 AQMAKAAAEERALFTDRMATRSTTQSNRTSRLIGKKMNRSVSLTIY
              610       620       630       640      

>>NP_001137448 (OMIM: 193525) wee1-like protein kinase i  (432 aa)
 initn: 2830 init1: 2830 opt: 2830  Z-score: 1241.1  bits: 239.3 E(85289): 2.2e-62
Smith-Waterman score: 2830; 100.0% identity (100.0% similar) in 432 aa overlap (215-646:1-432)

          190       200       210       220       230       240    
pF1KB3 FDTPHTPKSLLSKARGIDSSSVKLRGSSLFMDTEKSGKREFDVRQTPQVNINPFTPDSLL
                                     ::::::::::::::::::::::::::::::
NP_001                               MDTEKSGKREFDVRQTPQVNINPFTPDSLL
                                             10        20        30

          250       260       270       280       290       300    
pF1KB3 LHSSGQCRRRKRTYWNDSCGEDMEASDYELEDETRPAKRITITESNMKSRYTTEFHELEK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LHSSGQCRRRKRTYWNDSCGEDMEASDYELEDETRPAKRITITESNMKSRYTTEFHELEK
               40        50        60        70        80        90

          310       320       330       340       350       360    
pF1KB3 IGSGEFGSVFKCVKRLDGCIYAIKRSKKPLAGSVDEQNALREVYAHAVLGQHSHVVRYFS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IGSGEFGSVFKCVKRLDGCIYAIKRSKKPLAGSVDEQNALREVYAHAVLGQHSHVVRYFS
              100       110       120       130       140       150

          370       380       390       400       410       420    
pF1KB3 AWAEDDHMLIQNEYCNGGSLADAISENYRIMSYFKEAELKDLLLQVGRGLRYIHSMSLVH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AWAEDDHMLIQNEYCNGGSLADAISENYRIMSYFKEAELKDLLLQVGRGLRYIHSMSLVH
              160       170       180       190       200       210

          430       440       450       460       470       480    
pF1KB3 MDIKPSNIFISRTSIPNAASEEGDEDDWASNKVMFKIGDLGHVTRISSPQVEEGDSRFLA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MDIKPSNIFISRTSIPNAASEEGDEDDWASNKVMFKIGDLGHVTRISSPQVEEGDSRFLA
              220       230       240       250       260       270

          490       500       510       520       530       540    
pF1KB3 NEVLQENYTHLPKADIFALALTVVCAAGAEPLPRNGDQWHEIRQGRLPRIPQVLSQEFTE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NEVLQENYTHLPKADIFALALTVVCAAGAEPLPRNGDQWHEIRQGRLPRIPQVLSQEFTE
              280       290       300       310       320       330

          550       560       570       580       590       600    
pF1KB3 LLKVMIHPDPERRPSAMALVKHSVLLSASRKSAEQLRIELNAEKFKNSLLQKELKKAQMA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LLKVMIHPDPERRPSAMALVKHSVLLSASRKSAEQLRIELNAEKFKNSLLQKELKKAQMA
              340       350       360       370       380       390

          610       620       630       640      
pF1KB3 KAAAEERALFTDRMATRSTTQSNRTSRLIGKKMNRSVSLTIY
       ::::::::::::::::::::::::::::::::::::::::::
NP_001 KAAAEERALFTDRMATRSTTQSNRTSRLIGKKMNRSVSLTIY
              400       410       420       430  

>>NP_001099028 (OMIM: 614084) wee1-like protein kinase 2  (567 aa)
 initn: 1467 init1: 721 opt: 1400  Z-score: 627.0  bits: 126.1 E(85289): 3.5e-28
Smith-Waterman score: 1474; 51.7% identity (72.9% similar) in 484 aa overlap (168-644:92-559)

       140       150       160       170       180       190       
pF1KB3 FSPVRCGGPGDASPRGCGARRAGEGRRSPRPDHPGTPPHKTFRKLRLFDTPHTPKSLLSK
                                     :. :. :  ..  ::   :.: :::..::.
NP_001 NVHELDTSSEKDKESPDQILRTPVSHPLKCPETPAQPDSRS--KLLPSDSPSTPKTMLSR
              70        80        90       100         110         

       200       210       220       230       240          250    
pF1KB3 ARGIDSSSVKLRGSSLFMDTEKSGKREFDVRQTPQVNINPFTPDS---LLLHSSGQCRRR
            ....  :: . .  :    : :  . .   ::::::::.:   :.:.:.:  .:.
NP_001 LVISPTGKLPSRGPKHLKLTPAPLKDE--MTSLALVNINPFTPESYKKLFLQSGG--KRK
     120       130       140         150       160       170       

          260       270       280       290       300       310    
pF1KB3 KRTYWNDSCGEDMEASDYELEDETRPAKRITITESNMKSRYTTEFHELEKIGSGEFGSVF
        :       : :.: .  :      :::: .. :.:: :::  :: :.:::: ::::.:.
NP_001 IR-------G-DLEEAGPEEGKGGLPAKRCVLRETNMASRYEKEFLEVEKIGVGEFGTVY
                 180       190       200       210       220       

          320       330       340       350       360       370    
pF1KB3 KCVKRLDGCIYAIKRSKKPLAGSVDEQNALREVYAHAVLGQHSHVVRYFSAWAEDDHMLI
       ::.::::::.:::::: : ..   .:..::.:::::::::.: :::::.:.:::::::.:
NP_001 KCIKRLDGCVYAIKRSMKTFTELSNENSALHEVYAHAVLGHHPHVVRYYSSWAEDDHMII
       230       240       250       260       270       280       

          380       390       400       410       420       430    
pF1KB3 QNEYCNGGSLADAISENYRIMSYFKEAELKDLLLQVGRGLRYIHSMSLVHMDIKPSNIFI
       ::::::::::  ::::: .  ..:.: .:::.:::.. :: :::. :.::.:::::::::
NP_001 QNEYCNGGSLQAAISENTKSGNHFEEPKLKDILLQISLGLNYIHNSSMVHLDIKPSNIFI
       290       300       310       320       330       340       

            440        450        460       470       480       490
pF1KB3 SRT--SIPNAASEE-GDEDDW-ASNKVMFKIGDLGHVTRISSPQVEEGDSRFLANEVLQE
        .   :  ... ::  .: ::  : .::.:::::::.: :..:.::::::::::::.:::
NP_001 CHKMQSESSGVIEEVENEADWFLSANVMYKIGDLGHATSINKPKVEEGDSRFLANEILQE
       350       360       370       380       390       400       

              500       510       520       530       540       550
pF1KB3 NYTHLPKADIFALALTVVCAAGAEPLPRNGDQWHEIRQGRLPRIPQVLSQEFTELLKVMI
       .: ::::::::::.::.. ::::: :: ::  ::.::.: .: .:: ::. :. ::: ::
NP_001 DYRHLPKADIFALGLTIAVAAGAESLPTNGAAWHHIRKGNFPDVPQELSESFSSLLKNMI
       410       420       430       440       450       460       

              560       570       580       590       600       610
pF1KB3 HPDPERRPSAMALVKHSVLLSASRKSAEQLRIELNAEKFKNSLLQKELKKAQMAKAAAEE
       .:: :.:::: ::....::  .  :. :.:. .:: ::::.. :..::..::.:..  . 
NP_001 QPDAEQRPSAAALARNTVLRPSLGKT-EELQQQLNLEKFKTATLERELREAQQAQSP-QG
       470       480       490        500       510       520      

              620       630       640            
pF1KB3 RALFTDRMATRSTTQSNRTSRLIGKKMNRSVSLTIY      
        .   :  .. . : :  :.::.: :  :: :.:        
NP_001 YTHHGDTGVSGTHTGSRSTKRLVGGKSARSSSFTSGEREPLH
         530       540       550       560       




646 residues in 1 query   sequences
60827320 residues in 85289 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Thu Nov  3 12:22:27 2016 done: Thu Nov  3 12:22:28 2016
 Total Scan time: 13.540 Total Display time:  0.010

Function used was FASTA [36.3.4 Apr, 2011]
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