Result of FASTA (omim) for pF1KA1901
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KA1901, 1258 aa
  1>>>pF1KA1901 1258 - 1258 aa - 1258 aa
Library: /omim/omim.rfq.tfa
  60827320 residues in 85289 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 11.2348+/-0.000677; mu= -3.6292+/- 0.041
 mean_var=626.9939+/-135.540, 0's: 0 Z-trim(116.5): 1993  B-trim: 0 in 0/56
 Lambda= 0.051220
 statistics sampled from 25238 (27668) to 25238 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.644), E-opt: 0.2 (0.324), width:  16
 Scan time: 15.070

The best scores are:                                      opt bits E(85289)
NP_036356 (OMIM: 263520,604588) serine/threonine-p (1258) 8239 626.2 4.2e-178
XP_011530305 (OMIM: 263520,604588) PREDICTED: seri (1258) 8239 626.2 4.2e-178
XP_016863740 (OMIM: 263520,604588) PREDICTED: seri (1051) 6864 524.5 1.5e-147
XP_016863741 (OMIM: 263520,604588) PREDICTED: seri (1051) 6864 524.5 1.5e-147
NP_001186328 (OMIM: 263520,604588) serine/threonin (1189) 4788 371.2 2.4e-101
XP_011530306 (OMIM: 263520,604588) PREDICTED: seri (1214) 4788 371.2 2.4e-101
NP_001186329 (OMIM: 263520,604588) serine/threonin (1214) 4788 371.2 2.4e-101
NP_001186327 (OMIM: 263520,604588) serine/threonin (1242) 4624 359.1 1.1e-97
XP_016863743 (OMIM: 263520,604588) PREDICTED: seri ( 834) 4583 355.8   7e-97
XP_016863742 (OMIM: 263520,604588) PREDICTED: seri ( 902) 4583 355.9 7.3e-97
XP_016863739 (OMIM: 263520,604588) PREDICTED: seri (1079) 4583 356.0 8.1e-97
XP_016863738 (OMIM: 263520,604588) PREDICTED: seri (1079) 4583 356.0 8.1e-97
NP_001186326 (OMIM: 263520,604588) serine/threonin (1286) 4583 356.1   9e-97
XP_006714291 (OMIM: 263520,604588) PREDICTED: seri (1227) 3699 290.7   4e-77
XP_011530307 (OMIM: 263520,604588) PREDICTED: seri ( 715) 3684 289.3 6.4e-77
XP_011533370 (OMIM: 616731) PREDICTED: serine/thre ( 483) 1266 110.4 3.1e-23
XP_006719871 (OMIM: 616731) PREDICTED: serine/thre ( 598) 1266 110.5 3.5e-23
XP_011533368 (OMIM: 616731) PREDICTED: serine/thre ( 697) 1266 110.6 3.8e-23
NP_954983 (OMIM: 616731) serine/threonine-protein  ( 708) 1266 110.6 3.9e-23
XP_016876045 (OMIM: 616731) PREDICTED: serine/thre ( 737) 1266 110.6   4e-23
XP_016876044 (OMIM: 616731) PREDICTED: serine/thre ( 755) 1266 110.6   4e-23
XP_016876046 (OMIM: 616731) PREDICTED: serine/thre ( 780) 1266 110.7 4.1e-23
NP_001139571 (OMIM: 604044) serine/threonine-prote ( 489) 1094 97.7 2.1e-19
NP_689933 (OMIM: 604044) serine/threonine-protein  ( 506) 1088 97.2 2.9e-19
NP_002489 (OMIM: 604044) serine/threonine-protein  ( 506) 1088 97.2 2.9e-19
XP_011532342 (OMIM: 601959) PREDICTED: serine/thre ( 671)  979 89.4 9.1e-17
XP_006713373 (OMIM: 601959) PREDICTED: serine/thre ( 795)  979 89.5   1e-16
XP_016862575 (OMIM: 601959) PREDICTED: serine/thre ( 824)  979 89.5   1e-16
NP_003148 (OMIM: 601959) serine/threonine-protein  ( 841)  979 89.5   1e-16
XP_011532341 (OMIM: 601959) PREDICTED: serine/thre ( 842)  979 89.5   1e-16
XP_016862574 (OMIM: 601959) PREDICTED: serine/thre ( 870)  979 89.5 1.1e-16
NP_835464 (OMIM: 609799,613824,615415) serine/thre ( 692)  808 76.7 5.9e-13
XP_016879988 (OMIM: 609799,613824,615415) PREDICTE ( 705)  808 76.7   6e-13
XP_016879990 (OMIM: 609799,613824,615415) PREDICTE ( 484)  749 72.2 9.9e-12
NP_149107 (OMIM: 609798,614262,617022,617025) seri ( 979)  754 73.0 1.1e-11
NP_001316166 (OMIM: 609798,614262,617022,617025) s ( 991)  754 73.0 1.2e-11
XP_011522942 (OMIM: 609799,613824,615415) PREDICTE ( 716)  749 72.4 1.2e-11
XP_011522940 (OMIM: 609799,613824,615415) PREDICTE ( 729)  749 72.4 1.2e-11
NP_665917 (OMIM: 609779) serine/threonine-protein  ( 470)  741 71.5 1.5e-11
NP_001308152 (OMIM: 609779) serine/threonine-prote ( 482)  741 71.6 1.5e-11
XP_016862702 (OMIM: 609779) PREDICTED: serine/thre ( 599)  741 71.7 1.7e-11
NP_001139475 (OMIM: 609779) serine/threonine-prote ( 599)  741 71.7 1.7e-11
XP_016862703 (OMIM: 609779) PREDICTED: serine/thre ( 599)  741 71.7 1.7e-11
XP_011511469 (OMIM: 609779) PREDICTED: serine/thre ( 645)  741 71.7 1.8e-11
NP_001308149 (OMIM: 609779) serine/threonine-prote ( 645)  741 71.7 1.8e-11
NP_079076 (OMIM: 609779) serine/threonine-protein  ( 645)  741 71.7 1.8e-11
XP_016862704 (OMIM: 609779) PREDICTED: serine/thre ( 563)  734 71.1 2.3e-11
XP_016862705 (OMIM: 609779) PREDICTED: serine/thre ( 563)  734 71.1 2.3e-11
XP_016862701 (OMIM: 609779) PREDICTED: serine/thre ( 609)  734 71.2 2.4e-11
XP_016879989 (OMIM: 609799,613824,615415) PREDICTE ( 666)  719 70.1 5.5e-11


>>NP_036356 (OMIM: 263520,604588) serine/threonine-prote  (1258 aa)
 initn: 8239 init1: 8239 opt: 8239  Z-score: 3318.6  bits: 626.2 E(85289): 4.2e-178
Smith-Waterman score: 8239; 100.0% identity (100.0% similar) in 1258 aa overlap (1-1258:1-1258)

               10        20        30        40        50        60
pF1KA1 MEKYVRLQKIGEGSFGKAILVKSTEDGRQYVIKEINISRMSSKEREESRREVAVLANMKH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 MEKYVRLQKIGEGSFGKAILVKSTEDGRQYVIKEINISRMSSKEREESRREVAVLANMKH
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KA1 PNIVQYRESFEENGSLYIVMDYCEGGDLFKRINAQKGVLFQEDQILDWFVQICLALKHVH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 PNIVQYRESFEENGSLYIVMDYCEGGDLFKRINAQKGVLFQEDQILDWFVQICLALKHVH
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KA1 DRKILHRDIKSQNIFLTKDGTVQLGDFGIARVLNSTVELARTCIGTPYYLSPEICENKPY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 DRKILHRDIKSQNIFLTKDGTVQLGDFGIARVLNSTVELARTCIGTPYYLSPEICENKPY
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KA1 NNKSDIWALGCVLYELCTLKHAFEAGSMKNLVLKIISGSFPPVSLHYSYDLRSLVSQLFK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 NNKSDIWALGCVLYELCTLKHAFEAGSMKNLVLKIISGSFPPVSLHYSYDLRSLVSQLFK
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KA1 RNPRDRPSVNSILEKGFIAKRIEKFLSPQLIAEEFCLKTFSKFGSQPIPAKRPASGQNSI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 RNPRDRPSVNSILEKGFIAKRIEKFLSPQLIAEEFCLKTFSKFGSQPIPAKRPASGQNSI
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KA1 SVMPAQKITKPAAKYGIPLAYKKYGDKKLHEKKPLQKHKQAHQTPEKRVNTGEERRKISE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 SVMPAQKITKPAAKYGIPLAYKKYGDKKLHEKKPLQKHKQAHQTPEKRVNTGEERRKISE
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KA1 EAARKRRLEFIEKEKKQKDQIISLMKAEQMKRQEKERLERINRAREQGWRNVLSAGGSGE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 EAARKRRLEFIEKEKKQKDQIISLMKAEQMKRQEKERLERINRAREQGWRNVLSAGGSGE
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KA1 VKAPFLGSGGTIAPSSFSSRGQYEHYHAIFDQMQQQRAEDNEAKWKREIYGRGLPERGIL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 VKAPFLGSGGTIAPSSFSSRGQYEHYHAIFDQMQQQRAEDNEAKWKREIYGRGLPERGIL
              430       440       450       460       470       480

              490       500       510       520       530       540
pF1KA1 PGVRPGFPYGAAGHHHFPDADDIRKTLKRLKAVSKQANANRQKGQLAVERAKQVEEFLQR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 PGVRPGFPYGAAGHHHFPDADDIRKTLKRLKAVSKQANANRQKGQLAVERAKQVEEFLQR
              490       500       510       520       530       540

              550       560       570       580       590       600
pF1KA1 KREAMQNKARAEGHMVYLARLRQIRLQNFNERQQIKAKLRGEKKEANHSEGQEGSEEADM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 KREAMQNKARAEGHMVYLARLRQIRLQNFNERQQIKAKLRGEKKEANHSEGQEGSEEADM
              550       560       570       580       590       600

              610       620       630       640       650       660
pF1KA1 RRKKIESLKAHANARAAVLKEQLERKRKEAYEREKKVWEEHLVAKGVKSSDVSPPLGQHE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 RRKKIESLKAHANARAAVLKEQLERKRKEAYEREKKVWEEHLVAKGVKSSDVSPPLGQHE
              610       620       630       640       650       660

              670       680       690       700       710       720
pF1KA1 TGGSPSKQQMRSVISVTSALKEVGVDSSLTDTRETSEEMQKTNNAISSKREILRRLNENL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 TGGSPSKQQMRSVISVTSALKEVGVDSSLTDTRETSEEMQKTNNAISSKREILRRLNENL
              670       680       690       700       710       720

              730       740       750       760       770       780
pF1KA1 KAQEDEKGKQNLSDTFEINVHEDAKEHEKEKSVSSDRKKWEAGGQLVIPLDELTLDTSFS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 KAQEDEKGKQNLSDTFEINVHEDAKEHEKEKSVSSDRKKWEAGGQLVIPLDELTLDTSFS
              730       740       750       760       770       780

              790       800       810       820       830       840
pF1KA1 TTERHTVGEVIKLGPNGSPRRAWGKSPTDSVLKILGEAELQLQTELLENTTIRSEISPEG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 TTERHTVGEVIKLGPNGSPRRAWGKSPTDSVLKILGEAELQLQTELLENTTIRSEISPEG
              790       800       810       820       830       840

              850       860       870       880       890       900
pF1KA1 EKYKPLITGEKKVQCISHEINPSAIVDSPVETKSPEFSEASPQMSLKLEGNLEEPDDLET
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 EKYKPLITGEKKVQCISHEINPSAIVDSPVETKSPEFSEASPQMSLKLEGNLEEPDDLET
              850       860       870       880       890       900

              910       920       930       940       950       960
pF1KA1 EILQEPSGTNKDESLPCTITDVWISEEKETKETQSADRITIQENEVSEDGVSSTVDQLSD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 EILQEPSGTNKDESLPCTITDVWISEEKETKETQSADRITIQENEVSEDGVSSTVDQLSD
              910       920       930       940       950       960

              970       980       990      1000      1010      1020
pF1KA1 IHIEPGTNDSQHSKCDVDKSVQPEPFFHKVVHSEHLNLVPQVQSVQCSPEESFAFRSHSH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 IHIEPGTNDSQHSKCDVDKSVQPEPFFHKVVHSEHLNLVPQVQSVQCSPEESFAFRSHSH
              970       980       990      1000      1010      1020

             1030      1040      1050      1060      1070      1080
pF1KA1 LPPKNKNKNSLLIGLSTGLFDANNPKMLRTCSLPDLSKLFRTLMDVPTVGDVRQDNLEID
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 LPPKNKNKNSLLIGLSTGLFDANNPKMLRTCSLPDLSKLFRTLMDVPTVGDVRQDNLEID
             1030      1040      1050      1060      1070      1080

             1090      1100      1110      1120      1130      1140
pF1KA1 EIEDENIKEGPSDSEDIVFEETDTDLQELQASMEQLLREQPGEEYSEEEESVLKNSDVEP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 EIEDENIKEGPSDSEDIVFEETDTDLQELQASMEQLLREQPGEEYSEEEESVLKNSDVEP
             1090      1100      1110      1120      1130      1140

             1150      1160      1170      1180      1190      1200
pF1KA1 TANGTDVADEDDNPSSESALNEEWHSDNSDGEIASECECDSVFNHLEELRLHLEQEMGFE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 TANGTDVADEDDNPSSESALNEEWHSDNSDGEIASECECDSVFNHLEELRLHLEQEMGFE
             1150      1160      1170      1180      1190      1200

             1210      1220      1230      1240      1250        
pF1KA1 KFFEVYEKIKAIHEDEDENIEICSKIVQNILGNEHQHLYAKILHLVMADGAYQEDNDE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 KFFEVYEKIKAIHEDEDENIEICSKIVQNILGNEHQHLYAKILHLVMADGAYQEDNDE
             1210      1220      1230      1240      1250        

>>XP_011530305 (OMIM: 263520,604588) PREDICTED: serine/t  (1258 aa)
 initn: 8239 init1: 8239 opt: 8239  Z-score: 3318.6  bits: 626.2 E(85289): 4.2e-178
Smith-Waterman score: 8239; 100.0% identity (100.0% similar) in 1258 aa overlap (1-1258:1-1258)

               10        20        30        40        50        60
pF1KA1 MEKYVRLQKIGEGSFGKAILVKSTEDGRQYVIKEINISRMSSKEREESRREVAVLANMKH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MEKYVRLQKIGEGSFGKAILVKSTEDGRQYVIKEINISRMSSKEREESRREVAVLANMKH
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KA1 PNIVQYRESFEENGSLYIVMDYCEGGDLFKRINAQKGVLFQEDQILDWFVQICLALKHVH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PNIVQYRESFEENGSLYIVMDYCEGGDLFKRINAQKGVLFQEDQILDWFVQICLALKHVH
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KA1 DRKILHRDIKSQNIFLTKDGTVQLGDFGIARVLNSTVELARTCIGTPYYLSPEICENKPY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DRKILHRDIKSQNIFLTKDGTVQLGDFGIARVLNSTVELARTCIGTPYYLSPEICENKPY
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KA1 NNKSDIWALGCVLYELCTLKHAFEAGSMKNLVLKIISGSFPPVSLHYSYDLRSLVSQLFK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NNKSDIWALGCVLYELCTLKHAFEAGSMKNLVLKIISGSFPPVSLHYSYDLRSLVSQLFK
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KA1 RNPRDRPSVNSILEKGFIAKRIEKFLSPQLIAEEFCLKTFSKFGSQPIPAKRPASGQNSI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RNPRDRPSVNSILEKGFIAKRIEKFLSPQLIAEEFCLKTFSKFGSQPIPAKRPASGQNSI
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KA1 SVMPAQKITKPAAKYGIPLAYKKYGDKKLHEKKPLQKHKQAHQTPEKRVNTGEERRKISE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SVMPAQKITKPAAKYGIPLAYKKYGDKKLHEKKPLQKHKQAHQTPEKRVNTGEERRKISE
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KA1 EAARKRRLEFIEKEKKQKDQIISLMKAEQMKRQEKERLERINRAREQGWRNVLSAGGSGE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EAARKRRLEFIEKEKKQKDQIISLMKAEQMKRQEKERLERINRAREQGWRNVLSAGGSGE
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KA1 VKAPFLGSGGTIAPSSFSSRGQYEHYHAIFDQMQQQRAEDNEAKWKREIYGRGLPERGIL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VKAPFLGSGGTIAPSSFSSRGQYEHYHAIFDQMQQQRAEDNEAKWKREIYGRGLPERGIL
              430       440       450       460       470       480

              490       500       510       520       530       540
pF1KA1 PGVRPGFPYGAAGHHHFPDADDIRKTLKRLKAVSKQANANRQKGQLAVERAKQVEEFLQR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PGVRPGFPYGAAGHHHFPDADDIRKTLKRLKAVSKQANANRQKGQLAVERAKQVEEFLQR
              490       500       510       520       530       540

              550       560       570       580       590       600
pF1KA1 KREAMQNKARAEGHMVYLARLRQIRLQNFNERQQIKAKLRGEKKEANHSEGQEGSEEADM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KREAMQNKARAEGHMVYLARLRQIRLQNFNERQQIKAKLRGEKKEANHSEGQEGSEEADM
              550       560       570       580       590       600

              610       620       630       640       650       660
pF1KA1 RRKKIESLKAHANARAAVLKEQLERKRKEAYEREKKVWEEHLVAKGVKSSDVSPPLGQHE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RRKKIESLKAHANARAAVLKEQLERKRKEAYEREKKVWEEHLVAKGVKSSDVSPPLGQHE
              610       620       630       640       650       660

              670       680       690       700       710       720
pF1KA1 TGGSPSKQQMRSVISVTSALKEVGVDSSLTDTRETSEEMQKTNNAISSKREILRRLNENL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TGGSPSKQQMRSVISVTSALKEVGVDSSLTDTRETSEEMQKTNNAISSKREILRRLNENL
              670       680       690       700       710       720

              730       740       750       760       770       780
pF1KA1 KAQEDEKGKQNLSDTFEINVHEDAKEHEKEKSVSSDRKKWEAGGQLVIPLDELTLDTSFS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KAQEDEKGKQNLSDTFEINVHEDAKEHEKEKSVSSDRKKWEAGGQLVIPLDELTLDTSFS
              730       740       750       760       770       780

              790       800       810       820       830       840
pF1KA1 TTERHTVGEVIKLGPNGSPRRAWGKSPTDSVLKILGEAELQLQTELLENTTIRSEISPEG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TTERHTVGEVIKLGPNGSPRRAWGKSPTDSVLKILGEAELQLQTELLENTTIRSEISPEG
              790       800       810       820       830       840

              850       860       870       880       890       900
pF1KA1 EKYKPLITGEKKVQCISHEINPSAIVDSPVETKSPEFSEASPQMSLKLEGNLEEPDDLET
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EKYKPLITGEKKVQCISHEINPSAIVDSPVETKSPEFSEASPQMSLKLEGNLEEPDDLET
              850       860       870       880       890       900

              910       920       930       940       950       960
pF1KA1 EILQEPSGTNKDESLPCTITDVWISEEKETKETQSADRITIQENEVSEDGVSSTVDQLSD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EILQEPSGTNKDESLPCTITDVWISEEKETKETQSADRITIQENEVSEDGVSSTVDQLSD
              910       920       930       940       950       960

              970       980       990      1000      1010      1020
pF1KA1 IHIEPGTNDSQHSKCDVDKSVQPEPFFHKVVHSEHLNLVPQVQSVQCSPEESFAFRSHSH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 IHIEPGTNDSQHSKCDVDKSVQPEPFFHKVVHSEHLNLVPQVQSVQCSPEESFAFRSHSH
              970       980       990      1000      1010      1020

             1030      1040      1050      1060      1070      1080
pF1KA1 LPPKNKNKNSLLIGLSTGLFDANNPKMLRTCSLPDLSKLFRTLMDVPTVGDVRQDNLEID
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LPPKNKNKNSLLIGLSTGLFDANNPKMLRTCSLPDLSKLFRTLMDVPTVGDVRQDNLEID
             1030      1040      1050      1060      1070      1080

             1090      1100      1110      1120      1130      1140
pF1KA1 EIEDENIKEGPSDSEDIVFEETDTDLQELQASMEQLLREQPGEEYSEEEESVLKNSDVEP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EIEDENIKEGPSDSEDIVFEETDTDLQELQASMEQLLREQPGEEYSEEEESVLKNSDVEP
             1090      1100      1110      1120      1130      1140

             1150      1160      1170      1180      1190      1200
pF1KA1 TANGTDVADEDDNPSSESALNEEWHSDNSDGEIASECECDSVFNHLEELRLHLEQEMGFE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TANGTDVADEDDNPSSESALNEEWHSDNSDGEIASECECDSVFNHLEELRLHLEQEMGFE
             1150      1160      1170      1180      1190      1200

             1210      1220      1230      1240      1250        
pF1KA1 KFFEVYEKIKAIHEDEDENIEICSKIVQNILGNEHQHLYAKILHLVMADGAYQEDNDE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KFFEVYEKIKAIHEDEDENIEICSKIVQNILGNEHQHLYAKILHLVMADGAYQEDNDE
             1210      1220      1230      1240      1250        

>>XP_016863740 (OMIM: 263520,604588) PREDICTED: serine/t  (1051 aa)
 initn: 6864 init1: 6864 opt: 6864  Z-score: 2770.2  bits: 524.5 E(85289): 1.5e-147
Smith-Waterman score: 6864; 100.0% identity (100.0% similar) in 1051 aa overlap (208-1258:1-1051)

       180       190       200       210       220       230       
pF1KA1 KPYNNKSDIWALGCVLYELCTLKHAFEAGSMKNLVLKIISGSFPPVSLHYSYDLRSLVSQ
                                     ::::::::::::::::::::::::::::::
XP_016                               MKNLVLKIISGSFPPVSLHYSYDLRSLVSQ
                                             10        20        30

       240       250       260       270       280       290       
pF1KA1 LFKRNPRDRPSVNSILEKGFIAKRIEKFLSPQLIAEEFCLKTFSKFGSQPIPAKRPASGQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LFKRNPRDRPSVNSILEKGFIAKRIEKFLSPQLIAEEFCLKTFSKFGSQPIPAKRPASGQ
               40        50        60        70        80        90

       300       310       320       330       340       350       
pF1KA1 NSISVMPAQKITKPAAKYGIPLAYKKYGDKKLHEKKPLQKHKQAHQTPEKRVNTGEERRK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NSISVMPAQKITKPAAKYGIPLAYKKYGDKKLHEKKPLQKHKQAHQTPEKRVNTGEERRK
              100       110       120       130       140       150

       360       370       380       390       400       410       
pF1KA1 ISEEAARKRRLEFIEKEKKQKDQIISLMKAEQMKRQEKERLERINRAREQGWRNVLSAGG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ISEEAARKRRLEFIEKEKKQKDQIISLMKAEQMKRQEKERLERINRAREQGWRNVLSAGG
              160       170       180       190       200       210

       420       430       440       450       460       470       
pF1KA1 SGEVKAPFLGSGGTIAPSSFSSRGQYEHYHAIFDQMQQQRAEDNEAKWKREIYGRGLPER
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SGEVKAPFLGSGGTIAPSSFSSRGQYEHYHAIFDQMQQQRAEDNEAKWKREIYGRGLPER
              220       230       240       250       260       270

       480       490       500       510       520       530       
pF1KA1 GILPGVRPGFPYGAAGHHHFPDADDIRKTLKRLKAVSKQANANRQKGQLAVERAKQVEEF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GILPGVRPGFPYGAAGHHHFPDADDIRKTLKRLKAVSKQANANRQKGQLAVERAKQVEEF
              280       290       300       310       320       330

       540       550       560       570       580       590       
pF1KA1 LQRKREAMQNKARAEGHMVYLARLRQIRLQNFNERQQIKAKLRGEKKEANHSEGQEGSEE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LQRKREAMQNKARAEGHMVYLARLRQIRLQNFNERQQIKAKLRGEKKEANHSEGQEGSEE
              340       350       360       370       380       390

       600       610       620       630       640       650       
pF1KA1 ADMRRKKIESLKAHANARAAVLKEQLERKRKEAYEREKKVWEEHLVAKGVKSSDVSPPLG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ADMRRKKIESLKAHANARAAVLKEQLERKRKEAYEREKKVWEEHLVAKGVKSSDVSPPLG
              400       410       420       430       440       450

       660       670       680       690       700       710       
pF1KA1 QHETGGSPSKQQMRSVISVTSALKEVGVDSSLTDTRETSEEMQKTNNAISSKREILRRLN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QHETGGSPSKQQMRSVISVTSALKEVGVDSSLTDTRETSEEMQKTNNAISSKREILRRLN
              460       470       480       490       500       510

       720       730       740       750       760       770       
pF1KA1 ENLKAQEDEKGKQNLSDTFEINVHEDAKEHEKEKSVSSDRKKWEAGGQLVIPLDELTLDT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ENLKAQEDEKGKQNLSDTFEINVHEDAKEHEKEKSVSSDRKKWEAGGQLVIPLDELTLDT
              520       530       540       550       560       570

       780       790       800       810       820       830       
pF1KA1 SFSTTERHTVGEVIKLGPNGSPRRAWGKSPTDSVLKILGEAELQLQTELLENTTIRSEIS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SFSTTERHTVGEVIKLGPNGSPRRAWGKSPTDSVLKILGEAELQLQTELLENTTIRSEIS
              580       590       600       610       620       630

       840       850       860       870       880       890       
pF1KA1 PEGEKYKPLITGEKKVQCISHEINPSAIVDSPVETKSPEFSEASPQMSLKLEGNLEEPDD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PEGEKYKPLITGEKKVQCISHEINPSAIVDSPVETKSPEFSEASPQMSLKLEGNLEEPDD
              640       650       660       670       680       690

       900       910       920       930       940       950       
pF1KA1 LETEILQEPSGTNKDESLPCTITDVWISEEKETKETQSADRITIQENEVSEDGVSSTVDQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LETEILQEPSGTNKDESLPCTITDVWISEEKETKETQSADRITIQENEVSEDGVSSTVDQ
              700       710       720       730       740       750

       960       970       980       990      1000      1010       
pF1KA1 LSDIHIEPGTNDSQHSKCDVDKSVQPEPFFHKVVHSEHLNLVPQVQSVQCSPEESFAFRS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LSDIHIEPGTNDSQHSKCDVDKSVQPEPFFHKVVHSEHLNLVPQVQSVQCSPEESFAFRS
              760       770       780       790       800       810

      1020      1030      1040      1050      1060      1070       
pF1KA1 HSHLPPKNKNKNSLLIGLSTGLFDANNPKMLRTCSLPDLSKLFRTLMDVPTVGDVRQDNL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 HSHLPPKNKNKNSLLIGLSTGLFDANNPKMLRTCSLPDLSKLFRTLMDVPTVGDVRQDNL
              820       830       840       850       860       870

      1080      1090      1100      1110      1120      1130       
pF1KA1 EIDEIEDENIKEGPSDSEDIVFEETDTDLQELQASMEQLLREQPGEEYSEEEESVLKNSD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EIDEIEDENIKEGPSDSEDIVFEETDTDLQELQASMEQLLREQPGEEYSEEEESVLKNSD
              880       890       900       910       920       930

      1140      1150      1160      1170      1180      1190       
pF1KA1 VEPTANGTDVADEDDNPSSESALNEEWHSDNSDGEIASECECDSVFNHLEELRLHLEQEM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VEPTANGTDVADEDDNPSSESALNEEWHSDNSDGEIASECECDSVFNHLEELRLHLEQEM
              940       950       960       970       980       990

      1200      1210      1220      1230      1240      1250       
pF1KA1 GFEKFFEVYEKIKAIHEDEDENIEICSKIVQNILGNEHQHLYAKILHLVMADGAYQEDND
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GFEKFFEVYEKIKAIHEDEDENIEICSKIVQNILGNEHQHLYAKILHLVMADGAYQEDND
             1000      1010      1020      1030      1040      1050

        
pF1KA1 E
       :
XP_016 E
        

>>XP_016863741 (OMIM: 263520,604588) PREDICTED: serine/t  (1051 aa)
 initn: 6864 init1: 6864 opt: 6864  Z-score: 2770.2  bits: 524.5 E(85289): 1.5e-147
Smith-Waterman score: 6864; 100.0% identity (100.0% similar) in 1051 aa overlap (208-1258:1-1051)

       180       190       200       210       220       230       
pF1KA1 KPYNNKSDIWALGCVLYELCTLKHAFEAGSMKNLVLKIISGSFPPVSLHYSYDLRSLVSQ
                                     ::::::::::::::::::::::::::::::
XP_016                               MKNLVLKIISGSFPPVSLHYSYDLRSLVSQ
                                             10        20        30

       240       250       260       270       280       290       
pF1KA1 LFKRNPRDRPSVNSILEKGFIAKRIEKFLSPQLIAEEFCLKTFSKFGSQPIPAKRPASGQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LFKRNPRDRPSVNSILEKGFIAKRIEKFLSPQLIAEEFCLKTFSKFGSQPIPAKRPASGQ
               40        50        60        70        80        90

       300       310       320       330       340       350       
pF1KA1 NSISVMPAQKITKPAAKYGIPLAYKKYGDKKLHEKKPLQKHKQAHQTPEKRVNTGEERRK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NSISVMPAQKITKPAAKYGIPLAYKKYGDKKLHEKKPLQKHKQAHQTPEKRVNTGEERRK
              100       110       120       130       140       150

       360       370       380       390       400       410       
pF1KA1 ISEEAARKRRLEFIEKEKKQKDQIISLMKAEQMKRQEKERLERINRAREQGWRNVLSAGG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ISEEAARKRRLEFIEKEKKQKDQIISLMKAEQMKRQEKERLERINRAREQGWRNVLSAGG
              160       170       180       190       200       210

       420       430       440       450       460       470       
pF1KA1 SGEVKAPFLGSGGTIAPSSFSSRGQYEHYHAIFDQMQQQRAEDNEAKWKREIYGRGLPER
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SGEVKAPFLGSGGTIAPSSFSSRGQYEHYHAIFDQMQQQRAEDNEAKWKREIYGRGLPER
              220       230       240       250       260       270

       480       490       500       510       520       530       
pF1KA1 GILPGVRPGFPYGAAGHHHFPDADDIRKTLKRLKAVSKQANANRQKGQLAVERAKQVEEF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GILPGVRPGFPYGAAGHHHFPDADDIRKTLKRLKAVSKQANANRQKGQLAVERAKQVEEF
              280       290       300       310       320       330

       540       550       560       570       580       590       
pF1KA1 LQRKREAMQNKARAEGHMVYLARLRQIRLQNFNERQQIKAKLRGEKKEANHSEGQEGSEE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LQRKREAMQNKARAEGHMVYLARLRQIRLQNFNERQQIKAKLRGEKKEANHSEGQEGSEE
              340       350       360       370       380       390

       600       610       620       630       640       650       
pF1KA1 ADMRRKKIESLKAHANARAAVLKEQLERKRKEAYEREKKVWEEHLVAKGVKSSDVSPPLG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ADMRRKKIESLKAHANARAAVLKEQLERKRKEAYEREKKVWEEHLVAKGVKSSDVSPPLG
              400       410       420       430       440       450

       660       670       680       690       700       710       
pF1KA1 QHETGGSPSKQQMRSVISVTSALKEVGVDSSLTDTRETSEEMQKTNNAISSKREILRRLN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QHETGGSPSKQQMRSVISVTSALKEVGVDSSLTDTRETSEEMQKTNNAISSKREILRRLN
              460       470       480       490       500       510

       720       730       740       750       760       770       
pF1KA1 ENLKAQEDEKGKQNLSDTFEINVHEDAKEHEKEKSVSSDRKKWEAGGQLVIPLDELTLDT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ENLKAQEDEKGKQNLSDTFEINVHEDAKEHEKEKSVSSDRKKWEAGGQLVIPLDELTLDT
              520       530       540       550       560       570

       780       790       800       810       820       830       
pF1KA1 SFSTTERHTVGEVIKLGPNGSPRRAWGKSPTDSVLKILGEAELQLQTELLENTTIRSEIS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SFSTTERHTVGEVIKLGPNGSPRRAWGKSPTDSVLKILGEAELQLQTELLENTTIRSEIS
              580       590       600       610       620       630

       840       850       860       870       880       890       
pF1KA1 PEGEKYKPLITGEKKVQCISHEINPSAIVDSPVETKSPEFSEASPQMSLKLEGNLEEPDD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PEGEKYKPLITGEKKVQCISHEINPSAIVDSPVETKSPEFSEASPQMSLKLEGNLEEPDD
              640       650       660       670       680       690

       900       910       920       930       940       950       
pF1KA1 LETEILQEPSGTNKDESLPCTITDVWISEEKETKETQSADRITIQENEVSEDGVSSTVDQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LETEILQEPSGTNKDESLPCTITDVWISEEKETKETQSADRITIQENEVSEDGVSSTVDQ
              700       710       720       730       740       750

       960       970       980       990      1000      1010       
pF1KA1 LSDIHIEPGTNDSQHSKCDVDKSVQPEPFFHKVVHSEHLNLVPQVQSVQCSPEESFAFRS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LSDIHIEPGTNDSQHSKCDVDKSVQPEPFFHKVVHSEHLNLVPQVQSVQCSPEESFAFRS
              760       770       780       790       800       810

      1020      1030      1040      1050      1060      1070       
pF1KA1 HSHLPPKNKNKNSLLIGLSTGLFDANNPKMLRTCSLPDLSKLFRTLMDVPTVGDVRQDNL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 HSHLPPKNKNKNSLLIGLSTGLFDANNPKMLRTCSLPDLSKLFRTLMDVPTVGDVRQDNL
              820       830       840       850       860       870

      1080      1090      1100      1110      1120      1130       
pF1KA1 EIDEIEDENIKEGPSDSEDIVFEETDTDLQELQASMEQLLREQPGEEYSEEEESVLKNSD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EIDEIEDENIKEGPSDSEDIVFEETDTDLQELQASMEQLLREQPGEEYSEEEESVLKNSD
              880       890       900       910       920       930

      1140      1150      1160      1170      1180      1190       
pF1KA1 VEPTANGTDVADEDDNPSSESALNEEWHSDNSDGEIASECECDSVFNHLEELRLHLEQEM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VEPTANGTDVADEDDNPSSESALNEEWHSDNSDGEIASECECDSVFNHLEELRLHLEQEM
              940       950       960       970       980       990

      1200      1210      1220      1230      1240      1250       
pF1KA1 GFEKFFEVYEKIKAIHEDEDENIEICSKIVQNILGNEHQHLYAKILHLVMADGAYQEDND
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GFEKFFEVYEKIKAIHEDEDENIEICSKIVQNILGNEHQHLYAKILHLVMADGAYQEDND
             1000      1010      1020      1030      1040      1050

        
pF1KA1 E
       :
XP_016 E
        

>>NP_001186328 (OMIM: 263520,604588) serine/threonine-pr  (1189 aa)
 initn: 7378 init1: 4786 opt: 4788  Z-score: 1940.6  bits: 371.2 E(85289): 2.4e-101
Smith-Waterman score: 7610; 94.5% identity (94.5% similar) in 1258 aa overlap (1-1258:1-1189)

               10        20        30        40        50        60
pF1KA1 MEKYVRLQKIGEGSFGKAILVKSTEDGRQYVIKEINISRMSSKEREESRREVAVLANMKH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MEKYVRLQKIGEGSFGKAILVKSTEDGRQYVIKEINISRMSSKEREESRREVAVLANMKH
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KA1 PNIVQYRESFEENGSLYIVMDYCEGGDLFKRINAQKGVLFQEDQILDWFVQICLALKHVH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PNIVQYRESFEENGSLYIVMDYCEGGDLFKRINAQKGVLFQEDQILDWFVQICLALKHVH
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KA1 DRKILHRDIKSQNIFLTKDGTVQLGDFGIARVLNSTVELARTCIGTPYYLSPEICENKPY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DRKILHRDIKSQNIFLTKDGTVQLGDFGIARVLNSTVELARTCIGTPYYLSPEICENKPY
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KA1 NNKSDIWALGCVLYELCTLKHAFEAGSMKNLVLKIISGSFPPVSLHYSYDLRSLVSQLFK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NNKSDIWALGCVLYELCTLKHAFEAGSMKNLVLKIISGSFPPVSLHYSYDLRSLVSQLFK
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KA1 RNPRDRPSVNSILEKGFIAKRIEKFLSPQLIAEEFCLKTFSKFGSQPIPAKRPASGQNSI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RNPRDRPSVNSILEKGFIAKRIEKFLSPQLIAEEFCLKTFSKFGSQPIPAKRPASGQNSI
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KA1 SVMPAQKITKPAAKYGIPLAYKKYGDKKLHEKKPLQKHKQAHQTPEKRVNTGEERRKISE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SVMPAQKITKPAAKYGIPLAYKKYGDKKLHEKKPLQKHKQAHQTPEKRVNTGEERRKISE
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KA1 EAARKRRLEFIEKEKKQKDQIISLMKAEQMKRQEKERLERINRAREQGWRNVLSAGGSGE
       :::::::::::::::::::::::::::::::::::::                       
NP_001 EAARKRRLEFIEKEKKQKDQIISLMKAEQMKRQEKER-----------------------
              370       380       390                              

              430       440       450       460       470       480
pF1KA1 VKAPFLGSGGTIAPSSFSSRGQYEHYHAIFDQMQQQRAEDNEAKWKREIYGRGLPERGIL
         :::::::::::::::::::::::::::::::::::::::::::::::::::::::   
NP_001 --APFLGSGGTIAPSSFSSRGQYEHYHAIFDQMQQQRAEDNEAKWKREIYGRGLPER---
         400       410       420       430       440       450     

              490       500       510       520       530       540
pF1KA1 PGVRPGFPYGAAGHHHFPDADDIRKTLKRLKAVSKQANANRQKGQLAVERAKQVEEFLQR
                                                :::::::::::::::::::
NP_001 -----------------------------------------QKGQLAVERAKQVEEFLQR
                                                     460       470 

              550       560       570       580       590       600
pF1KA1 KREAMQNKARAEGHMVYLARLRQIRLQNFNERQQIKAKLRGEKKEANHSEGQEGSEEADM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KREAMQNKARAEGHMVYLARLRQIRLQNFNERQQIKAKLRGEKKEANHSEGQEGSEEADM
             480       490       500       510       520       530 

              610       620       630       640       650       660
pF1KA1 RRKKIESLKAHANARAAVLKEQLERKRKEAYEREKKVWEEHLVAKGVKSSDVSPPLGQHE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RRKKIESLKAHANARAAVLKEQLERKRKEAYEREKKVWEEHLVAKGVKSSDVSPPLGQHE
             540       550       560       570       580       590 

              670       680       690       700       710       720
pF1KA1 TGGSPSKQQMRSVISVTSALKEVGVDSSLTDTRETSEEMQKTNNAISSKREILRRLNENL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TGGSPSKQQMRSVISVTSALKEVGVDSSLTDTRETSEEMQKTNNAISSKREILRRLNENL
             600       610       620       630       640       650 

              730       740       750       760       770       780
pF1KA1 KAQEDEKGKQNLSDTFEINVHEDAKEHEKEKSVSSDRKKWEAGGQLVIPLDELTLDTSFS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KAQEDEKGKQNLSDTFEINVHEDAKEHEKEKSVSSDRKKWEAGGQLVIPLDELTLDTSFS
             660       670       680       690       700       710 

              790       800       810       820       830       840
pF1KA1 TTERHTVGEVIKLGPNGSPRRAWGKSPTDSVLKILGEAELQLQTELLENTTIRSEISPEG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TTERHTVGEVIKLGPNGSPRRAWGKSPTDSVLKILGEAELQLQTELLENTTIRSEISPEG
             720       730       740       750       760       770 

              850       860       870       880       890       900
pF1KA1 EKYKPLITGEKKVQCISHEINPSAIVDSPVETKSPEFSEASPQMSLKLEGNLEEPDDLET
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EKYKPLITGEKKVQCISHEINPSAIVDSPVETKSPEFSEASPQMSLKLEGNLEEPDDLET
             780       790       800       810       820       830 

              910       920       930       940       950       960
pF1KA1 EILQEPSGTNKDESLPCTITDVWISEEKETKETQSADRITIQENEVSEDGVSSTVDQLSD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EILQEPSGTNKDESLPCTITDVWISEEKETKETQSADRITIQENEVSEDGVSSTVDQLSD
             840       850       860       870       880       890 

              970       980       990      1000      1010      1020
pF1KA1 IHIEPGTNDSQHSKCDVDKSVQPEPFFHKVVHSEHLNLVPQVQSVQCSPEESFAFRSHSH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IHIEPGTNDSQHSKCDVDKSVQPEPFFHKVVHSEHLNLVPQVQSVQCSPEESFAFRSHSH
             900       910       920       930       940       950 

             1030      1040      1050      1060      1070      1080
pF1KA1 LPPKNKNKNSLLIGLSTGLFDANNPKMLRTCSLPDLSKLFRTLMDVPTVGDVRQDNLEID
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LPPKNKNKNSLLIGLSTGLFDANNPKMLRTCSLPDLSKLFRTLMDVPTVGDVRQDNLEID
             960       970       980       990      1000      1010 

             1090      1100      1110      1120      1130      1140
pF1KA1 EIEDENIKEGPSDSEDIVFEETDTDLQELQASMEQLLREQPGEEYSEEEESVLKNSDVEP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EIEDENIKEGPSDSEDIVFEETDTDLQELQASMEQLLREQPGEEYSEEEESVLKNSDVEP
            1020      1030      1040      1050      1060      1070 

             1150      1160      1170      1180      1190      1200
pF1KA1 TANGTDVADEDDNPSSESALNEEWHSDNSDGEIASECECDSVFNHLEELRLHLEQEMGFE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TANGTDVADEDDNPSSESALNEEWHSDNSDGEIASECECDSVFNHLEELRLHLEQEMGFE
            1080      1090      1100      1110      1120      1130 

             1210      1220      1230      1240      1250        
pF1KA1 KFFEVYEKIKAIHEDEDENIEICSKIVQNILGNEHQHLYAKILHLVMADGAYQEDNDE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KFFEVYEKIKAIHEDEDENIEICSKIVQNILGNEHQHLYAKILHLVMADGAYQEDNDE
            1140      1150      1160      1170      1180         

>>XP_011530306 (OMIM: 263520,604588) PREDICTED: serine/t  (1214 aa)
 initn: 4786 init1: 4786 opt: 4788  Z-score: 1940.5  bits: 371.2 E(85289): 2.4e-101
Smith-Waterman score: 7835; 96.5% identity (96.5% similar) in 1258 aa overlap (1-1258:1-1214)

               10        20        30        40        50        60
pF1KA1 MEKYVRLQKIGEGSFGKAILVKSTEDGRQYVIKEINISRMSSKEREESRREVAVLANMKH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MEKYVRLQKIGEGSFGKAILVKSTEDGRQYVIKEINISRMSSKEREESRREVAVLANMKH
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KA1 PNIVQYRESFEENGSLYIVMDYCEGGDLFKRINAQKGVLFQEDQILDWFVQICLALKHVH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PNIVQYRESFEENGSLYIVMDYCEGGDLFKRINAQKGVLFQEDQILDWFVQICLALKHVH
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KA1 DRKILHRDIKSQNIFLTKDGTVQLGDFGIARVLNSTVELARTCIGTPYYLSPEICENKPY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DRKILHRDIKSQNIFLTKDGTVQLGDFGIARVLNSTVELARTCIGTPYYLSPEICENKPY
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KA1 NNKSDIWALGCVLYELCTLKHAFEAGSMKNLVLKIISGSFPPVSLHYSYDLRSLVSQLFK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NNKSDIWALGCVLYELCTLKHAFEAGSMKNLVLKIISGSFPPVSLHYSYDLRSLVSQLFK
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KA1 RNPRDRPSVNSILEKGFIAKRIEKFLSPQLIAEEFCLKTFSKFGSQPIPAKRPASGQNSI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RNPRDRPSVNSILEKGFIAKRIEKFLSPQLIAEEFCLKTFSKFGSQPIPAKRPASGQNSI
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KA1 SVMPAQKITKPAAKYGIPLAYKKYGDKKLHEKKPLQKHKQAHQTPEKRVNTGEERRKISE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SVMPAQKITKPAAKYGIPLAYKKYGDKKLHEKKPLQKHKQAHQTPEKRVNTGEERRKISE
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KA1 EAARKRRLEFIEKEKKQKDQIISLMKAEQMKRQEKERLERINRAREQGWRNVLSAGGSGE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EAARKRRLEFIEKEKKQKDQIISLMKAEQMKRQEKERLERINRAREQGWRNVLSAGGSGE
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KA1 VKAPFLGSGGTIAPSSFSSRGQYEHYHAIFDQMQQQRAEDNEAKWKREIYGRGLPERGIL
       :::::::::::::::::::::::::::::::::::::::::::::::::::::::::   
XP_011 VKAPFLGSGGTIAPSSFSSRGQYEHYHAIFDQMQQQRAEDNEAKWKREIYGRGLPER---
              430       440       450       460       470          

              490       500       510       520       530       540
pF1KA1 PGVRPGFPYGAAGHHHFPDADDIRKTLKRLKAVSKQANANRQKGQLAVERAKQVEEFLQR
                                                :::::::::::::::::::
XP_011 -----------------------------------------QKGQLAVERAKQVEEFLQR
                                                480       490      

              550       560       570       580       590       600
pF1KA1 KREAMQNKARAEGHMVYLARLRQIRLQNFNERQQIKAKLRGEKKEANHSEGQEGSEEADM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KREAMQNKARAEGHMVYLARLRQIRLQNFNERQQIKAKLRGEKKEANHSEGQEGSEEADM
        500       510       520       530       540       550      

              610       620       630       640       650       660
pF1KA1 RRKKIESLKAHANARAAVLKEQLERKRKEAYEREKKVWEEHLVAKGVKSSDVSPPLGQHE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RRKKIESLKAHANARAAVLKEQLERKRKEAYEREKKVWEEHLVAKGVKSSDVSPPLGQHE
        560       570       580       590       600       610      

              670       680       690       700       710       720
pF1KA1 TGGSPSKQQMRSVISVTSALKEVGVDSSLTDTRETSEEMQKTNNAISSKREILRRLNENL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TGGSPSKQQMRSVISVTSALKEVGVDSSLTDTRETSEEMQKTNNAISSKREILRRLNENL
        620       630       640       650       660       670      

              730       740       750       760       770       780
pF1KA1 KAQEDEKGKQNLSDTFEINVHEDAKEHEKEKSVSSDRKKWEAGGQLVIPLDELTLDTSFS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KAQEDEKGKQNLSDTFEINVHEDAKEHEKEKSVSSDRKKWEAGGQLVIPLDELTLDTSFS
        680       690       700       710       720       730      

              790       800       810       820       830       840
pF1KA1 TTERHTVGEVIKLGPNGSPRRAWGKSPTDSVLKILGEAELQLQTELLENTTIRSEISPEG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TTERHTVGEVIKLGPNGSPRRAWGKSPTDSVLKILGEAELQLQTELLENTTIRSEISPEG
        740       750       760       770       780       790      

              850       860       870       880       890       900
pF1KA1 EKYKPLITGEKKVQCISHEINPSAIVDSPVETKSPEFSEASPQMSLKLEGNLEEPDDLET
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EKYKPLITGEKKVQCISHEINPSAIVDSPVETKSPEFSEASPQMSLKLEGNLEEPDDLET
        800       810       820       830       840       850      

              910       920       930       940       950       960
pF1KA1 EILQEPSGTNKDESLPCTITDVWISEEKETKETQSADRITIQENEVSEDGVSSTVDQLSD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EILQEPSGTNKDESLPCTITDVWISEEKETKETQSADRITIQENEVSEDGVSSTVDQLSD
        860       870       880       890       900       910      

              970       980       990      1000      1010      1020
pF1KA1 IHIEPGTNDSQHSKCDVDKSVQPEPFFHKVVHSEHLNLVPQVQSVQCSPEESFAFRSHSH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 IHIEPGTNDSQHSKCDVDKSVQPEPFFHKVVHSEHLNLVPQVQSVQCSPEESFAFRSHSH
        920       930       940       950       960       970      

             1030      1040      1050      1060      1070      1080
pF1KA1 LPPKNKNKNSLLIGLSTGLFDANNPKMLRTCSLPDLSKLFRTLMDVPTVGDVRQDNLEID
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LPPKNKNKNSLLIGLSTGLFDANNPKMLRTCSLPDLSKLFRTLMDVPTVGDVRQDNLEID
        980       990      1000      1010      1020      1030      

             1090      1100      1110      1120      1130      1140
pF1KA1 EIEDENIKEGPSDSEDIVFEETDTDLQELQASMEQLLREQPGEEYSEEEESVLKNSDVEP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EIEDENIKEGPSDSEDIVFEETDTDLQELQASMEQLLREQPGEEYSEEEESVLKNSDVEP
       1040      1050      1060      1070      1080      1090      

             1150      1160      1170      1180      1190      1200
pF1KA1 TANGTDVADEDDNPSSESALNEEWHSDNSDGEIASECECDSVFNHLEELRLHLEQEMGFE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TANGTDVADEDDNPSSESALNEEWHSDNSDGEIASECECDSVFNHLEELRLHLEQEMGFE
       1100      1110      1120      1130      1140      1150      

             1210      1220      1230      1240      1250        
pF1KA1 KFFEVYEKIKAIHEDEDENIEICSKIVQNILGNEHQHLYAKILHLVMADGAYQEDNDE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KFFEVYEKIKAIHEDEDENIEICSKIVQNILGNEHQHLYAKILHLVMADGAYQEDNDE
       1160      1170      1180      1190      1200      1210    

>>NP_001186329 (OMIM: 263520,604588) serine/threonine-pr  (1214 aa)
 initn: 4786 init1: 4786 opt: 4788  Z-score: 1940.5  bits: 371.2 E(85289): 2.4e-101
Smith-Waterman score: 7835; 96.5% identity (96.5% similar) in 1258 aa overlap (1-1258:1-1214)

               10        20        30        40        50        60
pF1KA1 MEKYVRLQKIGEGSFGKAILVKSTEDGRQYVIKEINISRMSSKEREESRREVAVLANMKH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MEKYVRLQKIGEGSFGKAILVKSTEDGRQYVIKEINISRMSSKEREESRREVAVLANMKH
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KA1 PNIVQYRESFEENGSLYIVMDYCEGGDLFKRINAQKGVLFQEDQILDWFVQICLALKHVH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PNIVQYRESFEENGSLYIVMDYCEGGDLFKRINAQKGVLFQEDQILDWFVQICLALKHVH
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KA1 DRKILHRDIKSQNIFLTKDGTVQLGDFGIARVLNSTVELARTCIGTPYYLSPEICENKPY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DRKILHRDIKSQNIFLTKDGTVQLGDFGIARVLNSTVELARTCIGTPYYLSPEICENKPY
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KA1 NNKSDIWALGCVLYELCTLKHAFEAGSMKNLVLKIISGSFPPVSLHYSYDLRSLVSQLFK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NNKSDIWALGCVLYELCTLKHAFEAGSMKNLVLKIISGSFPPVSLHYSYDLRSLVSQLFK
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KA1 RNPRDRPSVNSILEKGFIAKRIEKFLSPQLIAEEFCLKTFSKFGSQPIPAKRPASGQNSI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RNPRDRPSVNSILEKGFIAKRIEKFLSPQLIAEEFCLKTFSKFGSQPIPAKRPASGQNSI
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KA1 SVMPAQKITKPAAKYGIPLAYKKYGDKKLHEKKPLQKHKQAHQTPEKRVNTGEERRKISE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SVMPAQKITKPAAKYGIPLAYKKYGDKKLHEKKPLQKHKQAHQTPEKRVNTGEERRKISE
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KA1 EAARKRRLEFIEKEKKQKDQIISLMKAEQMKRQEKERLERINRAREQGWRNVLSAGGSGE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EAARKRRLEFIEKEKKQKDQIISLMKAEQMKRQEKERLERINRAREQGWRNVLSAGGSGE
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KA1 VKAPFLGSGGTIAPSSFSSRGQYEHYHAIFDQMQQQRAEDNEAKWKREIYGRGLPERGIL
       :::::::::::::::::::::::::::::::::::::::::::::::::::::::::   
NP_001 VKAPFLGSGGTIAPSSFSSRGQYEHYHAIFDQMQQQRAEDNEAKWKREIYGRGLPER---
              430       440       450       460       470          

              490       500       510       520       530       540
pF1KA1 PGVRPGFPYGAAGHHHFPDADDIRKTLKRLKAVSKQANANRQKGQLAVERAKQVEEFLQR
                                                :::::::::::::::::::
NP_001 -----------------------------------------QKGQLAVERAKQVEEFLQR
                                                480       490      

              550       560       570       580       590       600
pF1KA1 KREAMQNKARAEGHMVYLARLRQIRLQNFNERQQIKAKLRGEKKEANHSEGQEGSEEADM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KREAMQNKARAEGHMVYLARLRQIRLQNFNERQQIKAKLRGEKKEANHSEGQEGSEEADM
        500       510       520       530       540       550      

              610       620       630       640       650       660
pF1KA1 RRKKIESLKAHANARAAVLKEQLERKRKEAYEREKKVWEEHLVAKGVKSSDVSPPLGQHE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RRKKIESLKAHANARAAVLKEQLERKRKEAYEREKKVWEEHLVAKGVKSSDVSPPLGQHE
        560       570       580       590       600       610      

              670       680       690       700       710       720
pF1KA1 TGGSPSKQQMRSVISVTSALKEVGVDSSLTDTRETSEEMQKTNNAISSKREILRRLNENL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TGGSPSKQQMRSVISVTSALKEVGVDSSLTDTRETSEEMQKTNNAISSKREILRRLNENL
        620       630       640       650       660       670      

              730       740       750       760       770       780
pF1KA1 KAQEDEKGKQNLSDTFEINVHEDAKEHEKEKSVSSDRKKWEAGGQLVIPLDELTLDTSFS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KAQEDEKGKQNLSDTFEINVHEDAKEHEKEKSVSSDRKKWEAGGQLVIPLDELTLDTSFS
        680       690       700       710       720       730      

              790       800       810       820       830       840
pF1KA1 TTERHTVGEVIKLGPNGSPRRAWGKSPTDSVLKILGEAELQLQTELLENTTIRSEISPEG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TTERHTVGEVIKLGPNGSPRRAWGKSPTDSVLKILGEAELQLQTELLENTTIRSEISPEG
        740       750       760       770       780       790      

              850       860       870       880       890       900
pF1KA1 EKYKPLITGEKKVQCISHEINPSAIVDSPVETKSPEFSEASPQMSLKLEGNLEEPDDLET
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EKYKPLITGEKKVQCISHEINPSAIVDSPVETKSPEFSEASPQMSLKLEGNLEEPDDLET
        800       810       820       830       840       850      

              910       920       930       940       950       960
pF1KA1 EILQEPSGTNKDESLPCTITDVWISEEKETKETQSADRITIQENEVSEDGVSSTVDQLSD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EILQEPSGTNKDESLPCTITDVWISEEKETKETQSADRITIQENEVSEDGVSSTVDQLSD
        860       870       880       890       900       910      

              970       980       990      1000      1010      1020
pF1KA1 IHIEPGTNDSQHSKCDVDKSVQPEPFFHKVVHSEHLNLVPQVQSVQCSPEESFAFRSHSH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IHIEPGTNDSQHSKCDVDKSVQPEPFFHKVVHSEHLNLVPQVQSVQCSPEESFAFRSHSH
        920       930       940       950       960       970      

             1030      1040      1050      1060      1070      1080
pF1KA1 LPPKNKNKNSLLIGLSTGLFDANNPKMLRTCSLPDLSKLFRTLMDVPTVGDVRQDNLEID
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LPPKNKNKNSLLIGLSTGLFDANNPKMLRTCSLPDLSKLFRTLMDVPTVGDVRQDNLEID
        980       990      1000      1010      1020      1030      

             1090      1100      1110      1120      1130      1140
pF1KA1 EIEDENIKEGPSDSEDIVFEETDTDLQELQASMEQLLREQPGEEYSEEEESVLKNSDVEP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EIEDENIKEGPSDSEDIVFEETDTDLQELQASMEQLLREQPGEEYSEEEESVLKNSDVEP
       1040      1050      1060      1070      1080      1090      

             1150      1160      1170      1180      1190      1200
pF1KA1 TANGTDVADEDDNPSSESALNEEWHSDNSDGEIASECECDSVFNHLEELRLHLEQEMGFE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TANGTDVADEDDNPSSESALNEEWHSDNSDGEIASECECDSVFNHLEELRLHLEQEMGFE
       1100      1110      1120      1130      1140      1150      

             1210      1220      1230      1240      1250        
pF1KA1 KFFEVYEKIKAIHEDEDENIEICSKIVQNILGNEHQHLYAKILHLVMADGAYQEDNDE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KFFEVYEKIKAIHEDEDENIEICSKIVQNILGNEHQHLYAKILHLVMADGAYQEDNDE
       1160      1170      1180      1190      1200      1210    

>>NP_001186327 (OMIM: 263520,604588) serine/threonine-pr  (1242 aa)
 initn: 7702 init1: 4562 opt: 4624  Z-score: 1874.9  bits: 359.1 E(85289): 1.1e-97
Smith-Waterman score: 7769; 94.4% identity (94.4% similar) in 1286 aa overlap (1-1258:1-1242)

               10        20        30        40        50        60
pF1KA1 MEKYVRLQKIGEGSFGKAILVKSTEDGRQYVIKEINISRMSSKEREESRREVAVLANMKH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MEKYVRLQKIGEGSFGKAILVKSTEDGRQYVIKEINISRMSSKEREESRREVAVLANMKH
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KA1 PNIVQYRESFEENGSLYIVMDYCEGGDLFKRINAQKGVLFQEDQILDWFVQICLALKHVH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PNIVQYRESFEENGSLYIVMDYCEGGDLFKRINAQKGVLFQEDQILDWFVQICLALKHVH
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KA1 DRKILHRDIKSQNIFLTKDGTVQLGDFGIARVLNSTVELARTCIGTPYYLSPEICENKPY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DRKILHRDIKSQNIFLTKDGTVQLGDFGIARVLNSTVELARTCIGTPYYLSPEICENKPY
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KA1 NNKSDIWALGCVLYELCTLKHAFEAGSMKNLVLKIISGSFPPVSLHYSYDLRSLVSQLFK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NNKSDIWALGCVLYELCTLKHAFEAGSMKNLVLKIISGSFPPVSLHYSYDLRSLVSQLFK
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KA1 RNPRDRPSVNSILEKGFIAKRIEKFLSPQLIAEEFCLKTFSKFGSQPIPAKRPASGQNSI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RNPRDRPSVNSILEKGFIAKRIEKFLSPQLIAEEFCLKTFSKFGSQPIPAKRPASGQNSI
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KA1 SVMPAQKITKPAAKYGIPLAYKKYGDKKLHEKKPLQKHKQAHQTPEKRVNTGEERRKISE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SVMPAQKITKPAAKYGIPLAYKKYGDKKLHEKKPLQKHKQAHQTPEKRVNTGEERRKISE
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KA1 EAARKRRLEFIEKEKKQKDQIISLMKAEQMKRQEKERLERINRAREQGWRNVLSAGGSGE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EAARKRRLEFIEKEKKQKDQIISLMKAEQMKRQEKERLERINRAREQGWRNVLSAGGSGE
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KA1 VKAPFLGSGGTIAPSSFSSRGQYEHYHAIFDQMQQQRAEDNEAKWKREIYGRGLPERGIL
       :::::::::::::::::::::::::::::::::::::::::::::::::::::::::   
NP_001 VKAPFLGSGGTIAPSSFSSRGQYEHYHAIFDQMQQQRAEDNEAKWKREIYGRGLPER---
              430       440       450       460       470          

              490       500       510       520       530       540
pF1KA1 PGVRPGFPYGAAGHHHFPDADDIRKTLKRLKAVSKQANANRQKGQLAVERAKQVEEFLQR
                                                :::::::::::::::::::
NP_001 -----------------------------------------QKGQLAVERAKQVEEFLQR
                                                480       490      

              550                                   560       570  
pF1KA1 KREAMQNKARAEGHM----------------------------VYLARLRQIRLQNFNER
       :::::::::::::::                            :::::::::::::::::
NP_001 KREAMQNKARAEGHMGILQNLAAMYGGRPSSSRGGKPRNKEEEVYLARLRQIRLQNFNER
        500       510       520       530       540       550      

            580       590       600       610       620       630  
pF1KA1 QQIKAKLRGEKKEANHSEGQEGSEEADMRRKKIESLKAHANARAAVLKEQLERKRKEAYE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QQIKAKLRGEKKEANHSEGQEGSEEADMRRKKIESLKAHANARAAVLKEQLERKRKEAYE
        560       570       580       590       600       610      

            640       650       660       670       680       690  
pF1KA1 REKKVWEEHLVAKGVKSSDVSPPLGQHETGGSPSKQQMRSVISVTSALKEVGVDSSLTDT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 REKKVWEEHLVAKGVKSSDVSPPLGQHETGGSPSKQQMRSVISVTSALKEVGVDSSLTDT
        620       630       640       650       660       670      

            700       710       720       730       740       750  
pF1KA1 RETSEEMQKTNNAISSKREILRRLNENLKAQEDEKGKQNLSDTFEINVHEDAKEHEKEKS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RETSEEMQKTNNAISSKREILRRLNENLKAQEDEKGKQNLSDTFEINVHEDAKEHEKEKS
        680       690       700       710       720       730      

            760       770       780       790       800       810  
pF1KA1 VSSDRKKWEAGGQLVIPLDELTLDTSFSTTERHTVGEVIKLGPNGSPRRAWGKSPTDSVL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VSSDRKKWEAGGQLVIPLDELTLDTSFSTTERHTVGEVIKLGPNGSPRRAWGKSPTDSVL
        740       750       760       770       780       790      

            820       830       840       850       860       870  
pF1KA1 KILGEAELQLQTELLENTTIRSEISPEGEKYKPLITGEKKVQCISHEINPSAIVDSPVET
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KILGEAELQLQTELLENTTIRSEISPEGEKYKPLITGEKKVQCISHEINPSAIVDSPVET
        800       810       820       830       840       850      

            880       890       900       910       920       930  
pF1KA1 KSPEFSEASPQMSLKLEGNLEEPDDLETEILQEPSGTNKDESLPCTITDVWISEEKETKE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KSPEFSEASPQMSLKLEGNLEEPDDLETEILQEPSGTNKDESLPCTITDVWISEEKETKE
        860       870       880       890       900       910      

            940       950       960       970       980       990  
pF1KA1 TQSADRITIQENEVSEDGVSSTVDQLSDIHIEPGTNDSQHSKCDVDKSVQPEPFFHKVVH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TQSADRITIQENEVSEDGVSSTVDQLSDIHIEPGTNDSQHSKCDVDKSVQPEPFFHKVVH
        920       930       940       950       960       970      

           1000      1010      1020      1030      1040      1050  
pF1KA1 SEHLNLVPQVQSVQCSPEESFAFRSHSHLPPKNKNKNSLLIGLSTGLFDANNPKMLRTCS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SEHLNLVPQVQSVQCSPEESFAFRSHSHLPPKNKNKNSLLIGLSTGLFDANNPKMLRTCS
        980       990      1000      1010      1020      1030      

           1060      1070      1080      1090      1100      1110  
pF1KA1 LPDLSKLFRTLMDVPTVGDVRQDNLEIDEIEDENIKEGPSDSEDIVFEETDTDLQELQAS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LPDLSKLFRTLMDVPTVGDVRQDNLEIDEIEDENIKEGPSDSEDIVFEETDTDLQELQAS
       1040      1050      1060      1070      1080      1090      

           1120      1130      1140      1150      1160      1170  
pF1KA1 MEQLLREQPGEEYSEEEESVLKNSDVEPTANGTDVADEDDNPSSESALNEEWHSDNSDGE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MEQLLREQPGEEYSEEEESVLKNSDVEPTANGTDVADEDDNPSSESALNEEWHSDNSDGE
       1100      1110      1120      1130      1140      1150      

           1180      1190      1200      1210      1220      1230  
pF1KA1 IASECECDSVFNHLEELRLHLEQEMGFEKFFEVYEKIKAIHEDEDENIEICSKIVQNILG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IASECECDSVFNHLEELRLHLEQEMGFEKFFEVYEKIKAIHEDEDENIEICSKIVQNILG
       1160      1170      1180      1190      1200      1210      

           1240      1250        
pF1KA1 NEHQHLYAKILHLVMADGAYQEDNDE
       ::::::::::::::::::::::::::
NP_001 NEHQHLYAKILHLVMADGAYQEDNDE
       1220      1230      1240  

>>XP_016863743 (OMIM: 263520,604588) PREDICTED: serine/t  (834 aa)
 initn: 4562 init1: 4562 opt: 4583  Z-score: 1860.3  bits: 355.8 E(85289): 7e-97
Smith-Waterman score: 5195; 96.6% identity (96.6% similar) in 834 aa overlap (453-1258:1-834)

            430       440       450       460       470       480  
pF1KA1 APFLGSGGTIAPSSFSSRGQYEHYHAIFDQMQQQRAEDNEAKWKREIYGRGLPERGILPG
                                     ::::::::::::::::::::::::::::::
XP_016                               MQQQRAEDNEAKWKREIYGRGLPERGILPG
                                             10        20        30

            490       500       510       520       530       540  
pF1KA1 VRPGFPYGAAGHHHFPDADDIRKTLKRLKAVSKQANANRQKGQLAVERAKQVEEFLQRKR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VRPGFPYGAAGHHHFPDADDIRKTLKRLKAVSKQANANRQKGQLAVERAKQVEEFLQRKR
               40        50        60        70        80        90

            550                                   560       570    
pF1KA1 EAMQNKARAEGHM----------------------------VYLARLRQIRLQNFNERQQ
       :::::::::::::                            :::::::::::::::::::
XP_016 EAMQNKARAEGHMGILQNLAAMYGGRPSSSRGGKPRNKEEEVYLARLRQIRLQNFNERQQ
              100       110       120       130       140       150

          580       590       600       610       620       630    
pF1KA1 IKAKLRGEKKEANHSEGQEGSEEADMRRKKIESLKAHANARAAVLKEQLERKRKEAYERE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IKAKLRGEKKEANHSEGQEGSEEADMRRKKIESLKAHANARAAVLKEQLERKRKEAYERE
              160       170       180       190       200       210

          640       650       660       670       680       690    
pF1KA1 KKVWEEHLVAKGVKSSDVSPPLGQHETGGSPSKQQMRSVISVTSALKEVGVDSSLTDTRE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KKVWEEHLVAKGVKSSDVSPPLGQHETGGSPSKQQMRSVISVTSALKEVGVDSSLTDTRE
              220       230       240       250       260       270

          700       710       720       730       740       750    
pF1KA1 TSEEMQKTNNAISSKREILRRLNENLKAQEDEKGKQNLSDTFEINVHEDAKEHEKEKSVS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TSEEMQKTNNAISSKREILRRLNENLKAQEDEKGKQNLSDTFEINVHEDAKEHEKEKSVS
              280       290       300       310       320       330

          760       770       780       790       800       810    
pF1KA1 SDRKKWEAGGQLVIPLDELTLDTSFSTTERHTVGEVIKLGPNGSPRRAWGKSPTDSVLKI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SDRKKWEAGGQLVIPLDELTLDTSFSTTERHTVGEVIKLGPNGSPRRAWGKSPTDSVLKI
              340       350       360       370       380       390

          820       830       840       850       860       870    
pF1KA1 LGEAELQLQTELLENTTIRSEISPEGEKYKPLITGEKKVQCISHEINPSAIVDSPVETKS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LGEAELQLQTELLENTTIRSEISPEGEKYKPLITGEKKVQCISHEINPSAIVDSPVETKS
              400       410       420       430       440       450

          880       890       900       910       920       930    
pF1KA1 PEFSEASPQMSLKLEGNLEEPDDLETEILQEPSGTNKDESLPCTITDVWISEEKETKETQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PEFSEASPQMSLKLEGNLEEPDDLETEILQEPSGTNKDESLPCTITDVWISEEKETKETQ
              460       470       480       490       500       510

          940       950       960       970       980       990    
pF1KA1 SADRITIQENEVSEDGVSSTVDQLSDIHIEPGTNDSQHSKCDVDKSVQPEPFFHKVVHSE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SADRITIQENEVSEDGVSSTVDQLSDIHIEPGTNDSQHSKCDVDKSVQPEPFFHKVVHSE
              520       530       540       550       560       570

         1000      1010      1020      1030      1040      1050    
pF1KA1 HLNLVPQVQSVQCSPEESFAFRSHSHLPPKNKNKNSLLIGLSTGLFDANNPKMLRTCSLP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 HLNLVPQVQSVQCSPEESFAFRSHSHLPPKNKNKNSLLIGLSTGLFDANNPKMLRTCSLP
              580       590       600       610       620       630

         1060      1070      1080      1090      1100      1110    
pF1KA1 DLSKLFRTLMDVPTVGDVRQDNLEIDEIEDENIKEGPSDSEDIVFEETDTDLQELQASME
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DLSKLFRTLMDVPTVGDVRQDNLEIDEIEDENIKEGPSDSEDIVFEETDTDLQELQASME
              640       650       660       670       680       690

         1120      1130      1140      1150      1160      1170    
pF1KA1 QLLREQPGEEYSEEEESVLKNSDVEPTANGTDVADEDDNPSSESALNEEWHSDNSDGEIA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QLLREQPGEEYSEEEESVLKNSDVEPTANGTDVADEDDNPSSESALNEEWHSDNSDGEIA
              700       710       720       730       740       750

         1180      1190      1200      1210      1220      1230    
pF1KA1 SECECDSVFNHLEELRLHLEQEMGFEKFFEVYEKIKAIHEDEDENIEICSKIVQNILGNE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SECECDSVFNHLEELRLHLEQEMGFEKFFEVYEKIKAIHEDEDENIEICSKIVQNILGNE
              760       770       780       790       800       810

         1240      1250        
pF1KA1 HQHLYAKILHLVMADGAYQEDNDE
       ::::::::::::::::::::::::
XP_016 HQHLYAKILHLVMADGAYQEDNDE
              820       830    

>>XP_016863742 (OMIM: 263520,604588) PREDICTED: serine/t  (902 aa)
 initn: 4562 init1: 4562 opt: 4583  Z-score: 1860.0  bits: 355.9 E(85289): 7.3e-97
Smith-Waterman score: 5650; 96.9% identity (96.9% similar) in 902 aa overlap (385-1258:1-902)

          360       370       380       390       400       410    
pF1KA1 RRKISEEAARKRRLEFIEKEKKQKDQIISLMKAEQMKRQEKERLERINRAREQGWRNVLS
                                     ::::::::::::::::::::::::::::::
XP_016                               MKAEQMKRQEKERLERINRAREQGWRNVLS
                                             10        20        30

          420       430       440       450       460       470    
pF1KA1 AGGSGEVKAPFLGSGGTIAPSSFSSRGQYEHYHAIFDQMQQQRAEDNEAKWKREIYGRGL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AGGSGEVKAPFLGSGGTIAPSSFSSRGQYEHYHAIFDQMQQQRAEDNEAKWKREIYGRGL
               40        50        60        70        80        90

          480       490       500       510       520       530    
pF1KA1 PERGILPGVRPGFPYGAAGHHHFPDADDIRKTLKRLKAVSKQANANRQKGQLAVERAKQV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PERGILPGVRPGFPYGAAGHHHFPDADDIRKTLKRLKAVSKQANANRQKGQLAVERAKQV
              100       110       120       130       140       150

          540       550                                   560      
pF1KA1 EEFLQRKREAMQNKARAEGHM----------------------------VYLARLRQIRL
       :::::::::::::::::::::                            :::::::::::
XP_016 EEFLQRKREAMQNKARAEGHMGILQNLAAMYGGRPSSSRGGKPRNKEEEVYLARLRQIRL
              160       170       180       190       200       210

        570       580       590       600       610       620      
pF1KA1 QNFNERQQIKAKLRGEKKEANHSEGQEGSEEADMRRKKIESLKAHANARAAVLKEQLERK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QNFNERQQIKAKLRGEKKEANHSEGQEGSEEADMRRKKIESLKAHANARAAVLKEQLERK
              220       230       240       250       260       270

        630       640       650       660       670       680      
pF1KA1 RKEAYEREKKVWEEHLVAKGVKSSDVSPPLGQHETGGSPSKQQMRSVISVTSALKEVGVD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RKEAYEREKKVWEEHLVAKGVKSSDVSPPLGQHETGGSPSKQQMRSVISVTSALKEVGVD
              280       290       300       310       320       330

        690       700       710       720       730       740      
pF1KA1 SSLTDTRETSEEMQKTNNAISSKREILRRLNENLKAQEDEKGKQNLSDTFEINVHEDAKE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SSLTDTRETSEEMQKTNNAISSKREILRRLNENLKAQEDEKGKQNLSDTFEINVHEDAKE
              340       350       360       370       380       390

        750       760       770       780       790       800      
pF1KA1 HEKEKSVSSDRKKWEAGGQLVIPLDELTLDTSFSTTERHTVGEVIKLGPNGSPRRAWGKS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 HEKEKSVSSDRKKWEAGGQLVIPLDELTLDTSFSTTERHTVGEVIKLGPNGSPRRAWGKS
              400       410       420       430       440       450

        810       820       830       840       850       860      
pF1KA1 PTDSVLKILGEAELQLQTELLENTTIRSEISPEGEKYKPLITGEKKVQCISHEINPSAIV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PTDSVLKILGEAELQLQTELLENTTIRSEISPEGEKYKPLITGEKKVQCISHEINPSAIV
              460       470       480       490       500       510

        870       880       890       900       910       920      
pF1KA1 DSPVETKSPEFSEASPQMSLKLEGNLEEPDDLETEILQEPSGTNKDESLPCTITDVWISE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DSPVETKSPEFSEASPQMSLKLEGNLEEPDDLETEILQEPSGTNKDESLPCTITDVWISE
              520       530       540       550       560       570

        930       940       950       960       970       980      
pF1KA1 EKETKETQSADRITIQENEVSEDGVSSTVDQLSDIHIEPGTNDSQHSKCDVDKSVQPEPF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EKETKETQSADRITIQENEVSEDGVSSTVDQLSDIHIEPGTNDSQHSKCDVDKSVQPEPF
              580       590       600       610       620       630

        990      1000      1010      1020      1030      1040      
pF1KA1 FHKVVHSEHLNLVPQVQSVQCSPEESFAFRSHSHLPPKNKNKNSLLIGLSTGLFDANNPK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FHKVVHSEHLNLVPQVQSVQCSPEESFAFRSHSHLPPKNKNKNSLLIGLSTGLFDANNPK
              640       650       660       670       680       690

       1050      1060      1070      1080      1090      1100      
pF1KA1 MLRTCSLPDLSKLFRTLMDVPTVGDVRQDNLEIDEIEDENIKEGPSDSEDIVFEETDTDL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MLRTCSLPDLSKLFRTLMDVPTVGDVRQDNLEIDEIEDENIKEGPSDSEDIVFEETDTDL
              700       710       720       730       740       750

       1110      1120      1130      1140      1150      1160      
pF1KA1 QELQASMEQLLREQPGEEYSEEEESVLKNSDVEPTANGTDVADEDDNPSSESALNEEWHS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QELQASMEQLLREQPGEEYSEEEESVLKNSDVEPTANGTDVADEDDNPSSESALNEEWHS
              760       770       780       790       800       810

       1170      1180      1190      1200      1210      1220      
pF1KA1 DNSDGEIASECECDSVFNHLEELRLHLEQEMGFEKFFEVYEKIKAIHEDEDENIEICSKI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DNSDGEIASECECDSVFNHLEELRLHLEQEMGFEKFFEVYEKIKAIHEDEDENIEICSKI
              820       830       840       850       860       870

       1230      1240      1250        
pF1KA1 VQNILGNEHQHLYAKILHLVMADGAYQEDNDE
       ::::::::::::::::::::::::::::::::
XP_016 VQNILGNEHQHLYAKILHLVMADGAYQEDNDE
              880       890       900  




1258 residues in 1 query   sequences
60827320 residues in 85289 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Thu Nov  3 11:24:14 2016 done: Thu Nov  3 11:24:16 2016
 Total Scan time: 15.070 Total Display time:  0.580

Function used was FASTA [36.3.4 Apr, 2011]
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