Result of FASTA (omim) for
pF1KA1351
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KA1351, 1224 aa
1>>>pF1KA1351 1224 - 1224 aa - 1224 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.9582+/-0.000443; mu= 19.5264+/- 0.028
mean_var=88.4531+/-18.661, 0's: 0 Z-trim(110.2): 71 B-trim: 234 in 1/52
Lambda= 0.136370
statistics sampled from 18411 (18477) to 18411 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.572), E-opt: 0.2 (0.217), width: 16
Scan time: 13.050
The best scores are: opt bits E(85289)
NP_060587 (OMIM: 606417,614858) WD repeat-containi (1224) 8136 1612.1 0
XP_016871886 (OMIM: 606417,614858) PREDICTED: WD r (1166) 6949 1378.5 0
XP_005270020 (OMIM: 606417,614858) PREDICTED: WD r ( 965) 6388 1268.1 0
XP_005270019 (OMIM: 606417,614858) PREDICTED: WD r ( 965) 6388 1268.1 0
XP_016871887 (OMIM: 606417,614858) PREDICTED: WD r ( 965) 6388 1268.1 0
XP_016871888 (OMIM: 606417,614858) PREDICTED: WD r ( 795) 5240 1042.2 0
XP_016871889 (OMIM: 606417,614858) PREDICTED: WD r ( 781) 5204 1035.1 0
XP_005270021 (OMIM: 606417,614858) PREDICTED: WD r ( 753) 4968 988.7 0
>>NP_060587 (OMIM: 606417,614858) WD repeat-containing p (1224 aa)
initn: 8136 init1: 8136 opt: 8136 Z-score: 8646.9 bits: 1612.1 E(85289): 0
Smith-Waterman score: 8136; 100.0% identity (100.0% similar) in 1224 aa overlap (1-1224:1-1224)
10 20 30 40 50 60
pF1KA1 MLPYTVNFKVSARTLTGALNAHNKAAVDWGWQGLIAYGCHSLVVVIDSITAQTLQVLEKH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_060 MLPYTVNFKVSARTLTGALNAHNKAAVDWGWQGLIAYGCHSLVVVIDSITAQTLQVLEKH
10 20 30 40 50 60
70 80 90 100 110 120
pF1KA1 KADVVKVKWARENYHHNIGSPYCLRLASADVNGKIIVWDVAAGVAQCEIQEHAKPIQDVQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_060 KADVVKVKWARENYHHNIGSPYCLRLASADVNGKIIVWDVAAGVAQCEIQEHAKPIQDVQ
70 80 90 100 110 120
130 140 150 160 170 180
pF1KA1 WLWNQDASRDLLLAIHPPNYIVLWNADTGTKLWKKSYADNILSFSFDPFDPSHLTLLTSE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_060 WLWNQDASRDLLLAIHPPNYIVLWNADTGTKLWKKSYADNILSFSFDPFDPSHLTLLTSE
130 140 150 160 170 180
190 200 210 220 230 240
pF1KA1 GIVFISDFSPSKPPSGPGKKVYISSPHSSPAHNKLATATGAKKALNKVKILITQEKPSAE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_060 GIVFISDFSPSKPPSGPGKKVYISSPHSSPAHNKLATATGAKKALNKVKILITQEKPSAE
190 200 210 220 230 240
250 260 270 280 290 300
pF1KA1 FITLNDCLQLAYLPSKRNHMLLLYPREILILDLEVNQTVGVIAIERTGVPFLQVIPCFQR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_060 FITLNDCLQLAYLPSKRNHMLLLYPREILILDLEVNQTVGVIAIERTGVPFLQVIPCFQR
250 260 270 280 290 300
310 320 330 340 350 360
pF1KA1 DGLFCLHENGCITLRVRRSYNNIFTTSNEEPDPDPVQELTYDLRSQCDAIRVTKTVRPFS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_060 DGLFCLHENGCITLRVRRSYNNIFTTSNEEPDPDPVQELTYDLRSQCDAIRVTKTVRPFS
310 320 330 340 350 360
370 380 390 400 410 420
pF1KA1 MVCCPVNENAAALVVSDGRVMIWELKSAVCNRNSRNSSSGVSPLYSPVSFCGIPVGVLQN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_060 MVCCPVNENAAALVVSDGRVMIWELKSAVCNRNSRNSSSGVSPLYSPVSFCGIPVGVLQN
370 380 390 400 410 420
430 440 450 460 470 480
pF1KA1 KLPDLSLDNMIGQSAIAGEEHPRGSILREVHLKFLLTGLLSGLPAPQFAIRMCPPLTTKN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_060 KLPDLSLDNMIGQSAIAGEEHPRGSILREVHLKFLLTGLLSGLPAPQFAIRMCPPLTTKN
430 440 450 460 470 480
490 500 510 520 530 540
pF1KA1 IKMYQPLLAVGTSNGSVLVYHLTSGLLHKELSIHSCEVKGIEWTSLTSFLSFATSTPNNM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_060 IKMYQPLLAVGTSNGSVLVYHLTSGLLHKELSIHSCEVKGIEWTSLTSFLSFATSTPNNM
490 500 510 520 530 540
550 560 570 580 590 600
pF1KA1 GLVRNELQLVDLPTGRSIAFRGERGNDESAIEMIKVSHLKQYLAVVFRDKPLELWDVRTC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_060 GLVRNELQLVDLPTGRSIAFRGERGNDESAIEMIKVSHLKQYLAVVFRDKPLELWDVRTC
550 560 570 580 590 600
610 620 630 640 650 660
pF1KA1 TLLREMSKNFPTITALEWSPSHNLKSLRKKQLATREAMARQTVVSDTELSIVESSVISLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_060 TLLREMSKNFPTITALEWSPSHNLKSLRKKQLATREAMARQTVVSDTELSIVESSVISLL
610 620 630 640 650 660
670 680 690 700 710 720
pF1KA1 QEAESKSELSQNISAREHFVFTDIDGQVYHLTVEGNSVKDSARIPPDGSMGSITCIAWKG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_060 QEAESKSELSQNISAREHFVFTDIDGQVYHLTVEGNSVKDSARIPPDGSMGSITCIAWKG
670 680 690 700 710 720
730 740 750 760 770 780
pF1KA1 DTLVLGDMDGNLNFWDLKGRVSRGIPTHRSWVRKIRFAPGKGNQKLIAMYNDGAEVWDTK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_060 DTLVLGDMDGNLNFWDLKGRVSRGIPTHRSWVRKIRFAPGKGNQKLIAMYNDGAEVWDTK
730 740 750 760 770 780
790 800 810 820 830 840
pF1KA1 EVQMVSSLRSGRNVTFRILDVDWCTSDKVILASDDGCIRVLEMSMKSACFRMDEQELTEP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_060 EVQMVSSLRSGRNVTFRILDVDWCTSDKVILASDDGCIRVLEMSMKSACFRMDEQELTEP
790 800 810 820 830 840
850 860 870 880 890 900
pF1KA1 VWCPYLLVPRASLALKAFLLHQPWNGQYSLDISHVDYPENEEIKNLLQEQLNSLSNDIKK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_060 VWCPYLLVPRASLALKAFLLHQPWNGQYSLDISHVDYPENEEIKNLLQEQLNSLSNDIKK
850 860 870 880 890 900
910 920 930 940 950 960
pF1KA1 LLLDPEFTLLQRCLLVSRLYGDESELHFWTVAAHYLHSLSQEKSASTTAPKEAAPRDKLS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_060 LLLDPEFTLLQRCLLVSRLYGDESELHFWTVAAHYLHSLSQEKSASTTAPKEAAPRDKLS
910 920 930 940 950 960
970 980 990 1000 1010 1020
pF1KA1 NPLDICYDVLCENAYFQKFQLERVNLQEVKRSTYDHTRKCTDQLLLLGQTDRAVQLLLET
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_060 NPLDICYDVLCENAYFQKFQLERVNLQEVKRSTYDHTRKCTDQLLLLGQTDRAVQLLLET
970 980 990 1000 1010 1020
1030 1040 1050 1060 1070 1080
pF1KA1 SADNQHYYCDSLKACLVTTVTSSGPSQSTIKLVATNMIANGKLAEGVQLLCLIDKAADAC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_060 SADNQHYYCDSLKACLVTTVTSSGPSQSTIKLVATNMIANGKLAEGVQLLCLIDKAADAC
1030 1040 1050 1060 1070 1080
1090 1100 1110 1120 1130 1140
pF1KA1 RYLQTYGEWNRAAWLAKVRLNPEECADVLRRWVDHLCSPQVNQKSKALLVLLSLGCFFSV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_060 RYLQTYGEWNRAAWLAKVRLNPEECADVLRRWVDHLCSPQVNQKSKALLVLLSLGCFFSV
1090 1100 1110 1120 1130 1140
1150 1160 1170 1180 1190 1200
pF1KA1 AETLHSMRYFDRAALFVEACLKYGAFEVTEDTEKLITAIYADYARSLKNLGFKQGAVLFA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_060 AETLHSMRYFDRAALFVEACLKYGAFEVTEDTEKLITAIYADYARSLKNLGFKQGAVLFA
1150 1160 1170 1180 1190 1200
1210 1220
pF1KA1 SKAGAAGKDLLNELESPKEEPIEE
::::::::::::::::::::::::
NP_060 SKAGAAGKDLLNELESPKEEPIEE
1210 1220
>>XP_016871886 (OMIM: 606417,614858) PREDICTED: WD repea (1166 aa)
initn: 6928 init1: 6928 opt: 6949 Z-score: 7385.1 bits: 1378.5 E(85289): 0
Smith-Waterman score: 7590; 95.2% identity (95.3% similar) in 1224 aa overlap (1-1224:1-1166)
10 20 30 40 50 60
pF1KA1 MLPYTVNFKVSARTLTGALNAHNKAAVDWGWQGLIAYGCHSLVVVIDSITAQTLQVLEKH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MLPYTVNFKVSARTLTGALNAHNKAAVDWGWQGLIAYGCHSLVVVIDSITAQTLQVLEKH
10 20 30 40 50 60
70 80 90 100 110 120
pF1KA1 KADVVKVKWARENYHHNIGSPYCLRLASADVNGKIIVWDVAAGVAQCEIQEHAKPIQDVQ
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KADVVKVKWARENYHHNIGSPYCLRLASADVNGKIIVWDVAAGVAQCEIQEHAKPIQ---
70 80 90 100 110
130 140 150 160 170 180
pF1KA1 WLWNQDASRDLLLAIHPPNYIVLWNADTGTKLWKKSYADNILSFSFDPFDPSHLTLLTSE
.::::
XP_016 -------------------------------------------------------VLTSE
120
190 200 210 220 230 240
pF1KA1 GIVFISDFSPSKPPSGPGKKVYISSPHSSPAHNKLATATGAKKALNKVKILITQEKPSAE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GIVFISDFSPSKPPSGPGKKVYISSPHSSPAHNKLATATGAKKALNKVKILITQEKPSAE
130 140 150 160 170 180
250 260 270 280 290 300
pF1KA1 FITLNDCLQLAYLPSKRNHMLLLYPREILILDLEVNQTVGVIAIERTGVPFLQVIPCFQR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FITLNDCLQLAYLPSKRNHMLLLYPREILILDLEVNQTVGVIAIERTGVPFLQVIPCFQR
190 200 210 220 230 240
310 320 330 340 350 360
pF1KA1 DGLFCLHENGCITLRVRRSYNNIFTTSNEEPDPDPVQELTYDLRSQCDAIRVTKTVRPFS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DGLFCLHENGCITLRVRRSYNNIFTTSNEEPDPDPVQELTYDLRSQCDAIRVTKTVRPFS
250 260 270 280 290 300
370 380 390 400 410 420
pF1KA1 MVCCPVNENAAALVVSDGRVMIWELKSAVCNRNSRNSSSGVSPLYSPVSFCGIPVGVLQN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MVCCPVNENAAALVVSDGRVMIWELKSAVCNRNSRNSSSGVSPLYSPVSFCGIPVGVLQN
310 320 330 340 350 360
430 440 450 460 470 480
pF1KA1 KLPDLSLDNMIGQSAIAGEEHPRGSILREVHLKFLLTGLLSGLPAPQFAIRMCPPLTTKN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KLPDLSLDNMIGQSAIAGEEHPRGSILREVHLKFLLTGLLSGLPAPQFAIRMCPPLTTKN
370 380 390 400 410 420
490 500 510 520 530 540
pF1KA1 IKMYQPLLAVGTSNGSVLVYHLTSGLLHKELSIHSCEVKGIEWTSLTSFLSFATSTPNNM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IKMYQPLLAVGTSNGSVLVYHLTSGLLHKELSIHSCEVKGIEWTSLTSFLSFATSTPNNM
430 440 450 460 470 480
550 560 570 580 590 600
pF1KA1 GLVRNELQLVDLPTGRSIAFRGERGNDESAIEMIKVSHLKQYLAVVFRDKPLELWDVRTC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GLVRNELQLVDLPTGRSIAFRGERGNDESAIEMIKVSHLKQYLAVVFRDKPLELWDVRTC
490 500 510 520 530 540
610 620 630 640 650 660
pF1KA1 TLLREMSKNFPTITALEWSPSHNLKSLRKKQLATREAMARQTVVSDTELSIVESSVISLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TLLREMSKNFPTITALEWSPSHNLKSLRKKQLATREAMARQTVVSDTELSIVESSVISLL
550 560 570 580 590 600
670 680 690 700 710 720
pF1KA1 QEAESKSELSQNISAREHFVFTDIDGQVYHLTVEGNSVKDSARIPPDGSMGSITCIAWKG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QEAESKSELSQNISAREHFVFTDIDGQVYHLTVEGNSVKDSARIPPDGSMGSITCIAWKG
610 620 630 640 650 660
730 740 750 760 770 780
pF1KA1 DTLVLGDMDGNLNFWDLKGRVSRGIPTHRSWVRKIRFAPGKGNQKLIAMYNDGAEVWDTK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DTLVLGDMDGNLNFWDLKGRVSRGIPTHRSWVRKIRFAPGKGNQKLIAMYNDGAEVWDTK
670 680 690 700 710 720
790 800 810 820 830 840
pF1KA1 EVQMVSSLRSGRNVTFRILDVDWCTSDKVILASDDGCIRVLEMSMKSACFRMDEQELTEP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EVQMVSSLRSGRNVTFRILDVDWCTSDKVILASDDGCIRVLEMSMKSACFRMDEQELTEP
730 740 750 760 770 780
850 860 870 880 890 900
pF1KA1 VWCPYLLVPRASLALKAFLLHQPWNGQYSLDISHVDYPENEEIKNLLQEQLNSLSNDIKK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VWCPYLLVPRASLALKAFLLHQPWNGQYSLDISHVDYPENEEIKNLLQEQLNSLSNDIKK
790 800 810 820 830 840
910 920 930 940 950 960
pF1KA1 LLLDPEFTLLQRCLLVSRLYGDESELHFWTVAAHYLHSLSQEKSASTTAPKEAAPRDKLS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LLLDPEFTLLQRCLLVSRLYGDESELHFWTVAAHYLHSLSQEKSASTTAPKEAAPRDKLS
850 860 870 880 890 900
970 980 990 1000 1010 1020
pF1KA1 NPLDICYDVLCENAYFQKFQLERVNLQEVKRSTYDHTRKCTDQLLLLGQTDRAVQLLLET
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NPLDICYDVLCENAYFQKFQLERVNLQEVKRSTYDHTRKCTDQLLLLGQTDRAVQLLLET
910 920 930 940 950 960
1030 1040 1050 1060 1070 1080
pF1KA1 SADNQHYYCDSLKACLVTTVTSSGPSQSTIKLVATNMIANGKLAEGVQLLCLIDKAADAC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SADNQHYYCDSLKACLVTTVTSSGPSQSTIKLVATNMIANGKLAEGVQLLCLIDKAADAC
970 980 990 1000 1010 1020
1090 1100 1110 1120 1130 1140
pF1KA1 RYLQTYGEWNRAAWLAKVRLNPEECADVLRRWVDHLCSPQVNQKSKALLVLLSLGCFFSV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RYLQTYGEWNRAAWLAKVRLNPEECADVLRRWVDHLCSPQVNQKSKALLVLLSLGCFFSV
1030 1040 1050 1060 1070 1080
1150 1160 1170 1180 1190 1200
pF1KA1 AETLHSMRYFDRAALFVEACLKYGAFEVTEDTEKLITAIYADYARSLKNLGFKQGAVLFA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AETLHSMRYFDRAALFVEACLKYGAFEVTEDTEKLITAIYADYARSLKNLGFKQGAVLFA
1090 1100 1110 1120 1130 1140
1210 1220
pF1KA1 SKAGAAGKDLLNELESPKEEPIEE
::::::::::::::::::::::::
XP_016 SKAGAAGKDLLNELESPKEEPIEE
1150 1160
>>XP_005270020 (OMIM: 606417,614858) PREDICTED: WD repea (965 aa)
initn: 6388 init1: 6388 opt: 6388 Z-score: 6789.8 bits: 1268.1 E(85289): 0
Smith-Waterman score: 6388; 100.0% identity (100.0% similar) in 965 aa overlap (260-1224:1-965)
230 240 250 260 270 280
pF1KA1 ILITQEKPSAEFITLNDCLQLAYLPSKRNHMLLLYPREILILDLEVNQTVGVIAIERTGV
::::::::::::::::::::::::::::::
XP_005 MLLLYPREILILDLEVNQTVGVIAIERTGV
10 20 30
290 300 310 320 330 340
pF1KA1 PFLQVIPCFQRDGLFCLHENGCITLRVRRSYNNIFTTSNEEPDPDPVQELTYDLRSQCDA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 PFLQVIPCFQRDGLFCLHENGCITLRVRRSYNNIFTTSNEEPDPDPVQELTYDLRSQCDA
40 50 60 70 80 90
350 360 370 380 390 400
pF1KA1 IRVTKTVRPFSMVCCPVNENAAALVVSDGRVMIWELKSAVCNRNSRNSSSGVSPLYSPVS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 IRVTKTVRPFSMVCCPVNENAAALVVSDGRVMIWELKSAVCNRNSRNSSSGVSPLYSPVS
100 110 120 130 140 150
410 420 430 440 450 460
pF1KA1 FCGIPVGVLQNKLPDLSLDNMIGQSAIAGEEHPRGSILREVHLKFLLTGLLSGLPAPQFA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 FCGIPVGVLQNKLPDLSLDNMIGQSAIAGEEHPRGSILREVHLKFLLTGLLSGLPAPQFA
160 170 180 190 200 210
470 480 490 500 510 520
pF1KA1 IRMCPPLTTKNIKMYQPLLAVGTSNGSVLVYHLTSGLLHKELSIHSCEVKGIEWTSLTSF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 IRMCPPLTTKNIKMYQPLLAVGTSNGSVLVYHLTSGLLHKELSIHSCEVKGIEWTSLTSF
220 230 240 250 260 270
530 540 550 560 570 580
pF1KA1 LSFATSTPNNMGLVRNELQLVDLPTGRSIAFRGERGNDESAIEMIKVSHLKQYLAVVFRD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LSFATSTPNNMGLVRNELQLVDLPTGRSIAFRGERGNDESAIEMIKVSHLKQYLAVVFRD
280 290 300 310 320 330
590 600 610 620 630 640
pF1KA1 KPLELWDVRTCTLLREMSKNFPTITALEWSPSHNLKSLRKKQLATREAMARQTVVSDTEL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 KPLELWDVRTCTLLREMSKNFPTITALEWSPSHNLKSLRKKQLATREAMARQTVVSDTEL
340 350 360 370 380 390
650 660 670 680 690 700
pF1KA1 SIVESSVISLLQEAESKSELSQNISAREHFVFTDIDGQVYHLTVEGNSVKDSARIPPDGS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SIVESSVISLLQEAESKSELSQNISAREHFVFTDIDGQVYHLTVEGNSVKDSARIPPDGS
400 410 420 430 440 450
710 720 730 740 750 760
pF1KA1 MGSITCIAWKGDTLVLGDMDGNLNFWDLKGRVSRGIPTHRSWVRKIRFAPGKGNQKLIAM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MGSITCIAWKGDTLVLGDMDGNLNFWDLKGRVSRGIPTHRSWVRKIRFAPGKGNQKLIAM
460 470 480 490 500 510
770 780 790 800 810 820
pF1KA1 YNDGAEVWDTKEVQMVSSLRSGRNVTFRILDVDWCTSDKVILASDDGCIRVLEMSMKSAC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 YNDGAEVWDTKEVQMVSSLRSGRNVTFRILDVDWCTSDKVILASDDGCIRVLEMSMKSAC
520 530 540 550 560 570
830 840 850 860 870 880
pF1KA1 FRMDEQELTEPVWCPYLLVPRASLALKAFLLHQPWNGQYSLDISHVDYPENEEIKNLLQE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 FRMDEQELTEPVWCPYLLVPRASLALKAFLLHQPWNGQYSLDISHVDYPENEEIKNLLQE
580 590 600 610 620 630
890 900 910 920 930 940
pF1KA1 QLNSLSNDIKKLLLDPEFTLLQRCLLVSRLYGDESELHFWTVAAHYLHSLSQEKSASTTA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 QLNSLSNDIKKLLLDPEFTLLQRCLLVSRLYGDESELHFWTVAAHYLHSLSQEKSASTTA
640 650 660 670 680 690
950 960 970 980 990 1000
pF1KA1 PKEAAPRDKLSNPLDICYDVLCENAYFQKFQLERVNLQEVKRSTYDHTRKCTDQLLLLGQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 PKEAAPRDKLSNPLDICYDVLCENAYFQKFQLERVNLQEVKRSTYDHTRKCTDQLLLLGQ
700 710 720 730 740 750
1010 1020 1030 1040 1050 1060
pF1KA1 TDRAVQLLLETSADNQHYYCDSLKACLVTTVTSSGPSQSTIKLVATNMIANGKLAEGVQL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 TDRAVQLLLETSADNQHYYCDSLKACLVTTVTSSGPSQSTIKLVATNMIANGKLAEGVQL
760 770 780 790 800 810
1070 1080 1090 1100 1110 1120
pF1KA1 LCLIDKAADACRYLQTYGEWNRAAWLAKVRLNPEECADVLRRWVDHLCSPQVNQKSKALL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LCLIDKAADACRYLQTYGEWNRAAWLAKVRLNPEECADVLRRWVDHLCSPQVNQKSKALL
820 830 840 850 860 870
1130 1140 1150 1160 1170 1180
pF1KA1 VLLSLGCFFSVAETLHSMRYFDRAALFVEACLKYGAFEVTEDTEKLITAIYADYARSLKN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 VLLSLGCFFSVAETLHSMRYFDRAALFVEACLKYGAFEVTEDTEKLITAIYADYARSLKN
880 890 900 910 920 930
1190 1200 1210 1220
pF1KA1 LGFKQGAVLFASKAGAAGKDLLNELESPKEEPIEE
:::::::::::::::::::::::::::::::::::
XP_005 LGFKQGAVLFASKAGAAGKDLLNELESPKEEPIEE
940 950 960
>>XP_005270019 (OMIM: 606417,614858) PREDICTED: WD repea (965 aa)
initn: 6388 init1: 6388 opt: 6388 Z-score: 6789.8 bits: 1268.1 E(85289): 0
Smith-Waterman score: 6388; 100.0% identity (100.0% similar) in 965 aa overlap (260-1224:1-965)
230 240 250 260 270 280
pF1KA1 ILITQEKPSAEFITLNDCLQLAYLPSKRNHMLLLYPREILILDLEVNQTVGVIAIERTGV
::::::::::::::::::::::::::::::
XP_005 MLLLYPREILILDLEVNQTVGVIAIERTGV
10 20 30
290 300 310 320 330 340
pF1KA1 PFLQVIPCFQRDGLFCLHENGCITLRVRRSYNNIFTTSNEEPDPDPVQELTYDLRSQCDA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 PFLQVIPCFQRDGLFCLHENGCITLRVRRSYNNIFTTSNEEPDPDPVQELTYDLRSQCDA
40 50 60 70 80 90
350 360 370 380 390 400
pF1KA1 IRVTKTVRPFSMVCCPVNENAAALVVSDGRVMIWELKSAVCNRNSRNSSSGVSPLYSPVS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 IRVTKTVRPFSMVCCPVNENAAALVVSDGRVMIWELKSAVCNRNSRNSSSGVSPLYSPVS
100 110 120 130 140 150
410 420 430 440 450 460
pF1KA1 FCGIPVGVLQNKLPDLSLDNMIGQSAIAGEEHPRGSILREVHLKFLLTGLLSGLPAPQFA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 FCGIPVGVLQNKLPDLSLDNMIGQSAIAGEEHPRGSILREVHLKFLLTGLLSGLPAPQFA
160 170 180 190 200 210
470 480 490 500 510 520
pF1KA1 IRMCPPLTTKNIKMYQPLLAVGTSNGSVLVYHLTSGLLHKELSIHSCEVKGIEWTSLTSF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 IRMCPPLTTKNIKMYQPLLAVGTSNGSVLVYHLTSGLLHKELSIHSCEVKGIEWTSLTSF
220 230 240 250 260 270
530 540 550 560 570 580
pF1KA1 LSFATSTPNNMGLVRNELQLVDLPTGRSIAFRGERGNDESAIEMIKVSHLKQYLAVVFRD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LSFATSTPNNMGLVRNELQLVDLPTGRSIAFRGERGNDESAIEMIKVSHLKQYLAVVFRD
280 290 300 310 320 330
590 600 610 620 630 640
pF1KA1 KPLELWDVRTCTLLREMSKNFPTITALEWSPSHNLKSLRKKQLATREAMARQTVVSDTEL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 KPLELWDVRTCTLLREMSKNFPTITALEWSPSHNLKSLRKKQLATREAMARQTVVSDTEL
340 350 360 370 380 390
650 660 670 680 690 700
pF1KA1 SIVESSVISLLQEAESKSELSQNISAREHFVFTDIDGQVYHLTVEGNSVKDSARIPPDGS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SIVESSVISLLQEAESKSELSQNISAREHFVFTDIDGQVYHLTVEGNSVKDSARIPPDGS
400 410 420 430 440 450
710 720 730 740 750 760
pF1KA1 MGSITCIAWKGDTLVLGDMDGNLNFWDLKGRVSRGIPTHRSWVRKIRFAPGKGNQKLIAM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MGSITCIAWKGDTLVLGDMDGNLNFWDLKGRVSRGIPTHRSWVRKIRFAPGKGNQKLIAM
460 470 480 490 500 510
770 780 790 800 810 820
pF1KA1 YNDGAEVWDTKEVQMVSSLRSGRNVTFRILDVDWCTSDKVILASDDGCIRVLEMSMKSAC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 YNDGAEVWDTKEVQMVSSLRSGRNVTFRILDVDWCTSDKVILASDDGCIRVLEMSMKSAC
520 530 540 550 560 570
830 840 850 860 870 880
pF1KA1 FRMDEQELTEPVWCPYLLVPRASLALKAFLLHQPWNGQYSLDISHVDYPENEEIKNLLQE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 FRMDEQELTEPVWCPYLLVPRASLALKAFLLHQPWNGQYSLDISHVDYPENEEIKNLLQE
580 590 600 610 620 630
890 900 910 920 930 940
pF1KA1 QLNSLSNDIKKLLLDPEFTLLQRCLLVSRLYGDESELHFWTVAAHYLHSLSQEKSASTTA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 QLNSLSNDIKKLLLDPEFTLLQRCLLVSRLYGDESELHFWTVAAHYLHSLSQEKSASTTA
640 650 660 670 680 690
950 960 970 980 990 1000
pF1KA1 PKEAAPRDKLSNPLDICYDVLCENAYFQKFQLERVNLQEVKRSTYDHTRKCTDQLLLLGQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 PKEAAPRDKLSNPLDICYDVLCENAYFQKFQLERVNLQEVKRSTYDHTRKCTDQLLLLGQ
700 710 720 730 740 750
1010 1020 1030 1040 1050 1060
pF1KA1 TDRAVQLLLETSADNQHYYCDSLKACLVTTVTSSGPSQSTIKLVATNMIANGKLAEGVQL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 TDRAVQLLLETSADNQHYYCDSLKACLVTTVTSSGPSQSTIKLVATNMIANGKLAEGVQL
760 770 780 790 800 810
1070 1080 1090 1100 1110 1120
pF1KA1 LCLIDKAADACRYLQTYGEWNRAAWLAKVRLNPEECADVLRRWVDHLCSPQVNQKSKALL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LCLIDKAADACRYLQTYGEWNRAAWLAKVRLNPEECADVLRRWVDHLCSPQVNQKSKALL
820 830 840 850 860 870
1130 1140 1150 1160 1170 1180
pF1KA1 VLLSLGCFFSVAETLHSMRYFDRAALFVEACLKYGAFEVTEDTEKLITAIYADYARSLKN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 VLLSLGCFFSVAETLHSMRYFDRAALFVEACLKYGAFEVTEDTEKLITAIYADYARSLKN
880 890 900 910 920 930
1190 1200 1210 1220
pF1KA1 LGFKQGAVLFASKAGAAGKDLLNELESPKEEPIEE
:::::::::::::::::::::::::::::::::::
XP_005 LGFKQGAVLFASKAGAAGKDLLNELESPKEEPIEE
940 950 960
>>XP_016871887 (OMIM: 606417,614858) PREDICTED: WD repea (965 aa)
initn: 6388 init1: 6388 opt: 6388 Z-score: 6789.8 bits: 1268.1 E(85289): 0
Smith-Waterman score: 6388; 100.0% identity (100.0% similar) in 965 aa overlap (260-1224:1-965)
230 240 250 260 270 280
pF1KA1 ILITQEKPSAEFITLNDCLQLAYLPSKRNHMLLLYPREILILDLEVNQTVGVIAIERTGV
::::::::::::::::::::::::::::::
XP_016 MLLLYPREILILDLEVNQTVGVIAIERTGV
10 20 30
290 300 310 320 330 340
pF1KA1 PFLQVIPCFQRDGLFCLHENGCITLRVRRSYNNIFTTSNEEPDPDPVQELTYDLRSQCDA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PFLQVIPCFQRDGLFCLHENGCITLRVRRSYNNIFTTSNEEPDPDPVQELTYDLRSQCDA
40 50 60 70 80 90
350 360 370 380 390 400
pF1KA1 IRVTKTVRPFSMVCCPVNENAAALVVSDGRVMIWELKSAVCNRNSRNSSSGVSPLYSPVS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IRVTKTVRPFSMVCCPVNENAAALVVSDGRVMIWELKSAVCNRNSRNSSSGVSPLYSPVS
100 110 120 130 140 150
410 420 430 440 450 460
pF1KA1 FCGIPVGVLQNKLPDLSLDNMIGQSAIAGEEHPRGSILREVHLKFLLTGLLSGLPAPQFA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FCGIPVGVLQNKLPDLSLDNMIGQSAIAGEEHPRGSILREVHLKFLLTGLLSGLPAPQFA
160 170 180 190 200 210
470 480 490 500 510 520
pF1KA1 IRMCPPLTTKNIKMYQPLLAVGTSNGSVLVYHLTSGLLHKELSIHSCEVKGIEWTSLTSF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IRMCPPLTTKNIKMYQPLLAVGTSNGSVLVYHLTSGLLHKELSIHSCEVKGIEWTSLTSF
220 230 240 250 260 270
530 540 550 560 570 580
pF1KA1 LSFATSTPNNMGLVRNELQLVDLPTGRSIAFRGERGNDESAIEMIKVSHLKQYLAVVFRD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LSFATSTPNNMGLVRNELQLVDLPTGRSIAFRGERGNDESAIEMIKVSHLKQYLAVVFRD
280 290 300 310 320 330
590 600 610 620 630 640
pF1KA1 KPLELWDVRTCTLLREMSKNFPTITALEWSPSHNLKSLRKKQLATREAMARQTVVSDTEL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KPLELWDVRTCTLLREMSKNFPTITALEWSPSHNLKSLRKKQLATREAMARQTVVSDTEL
340 350 360 370 380 390
650 660 670 680 690 700
pF1KA1 SIVESSVISLLQEAESKSELSQNISAREHFVFTDIDGQVYHLTVEGNSVKDSARIPPDGS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SIVESSVISLLQEAESKSELSQNISAREHFVFTDIDGQVYHLTVEGNSVKDSARIPPDGS
400 410 420 430 440 450
710 720 730 740 750 760
pF1KA1 MGSITCIAWKGDTLVLGDMDGNLNFWDLKGRVSRGIPTHRSWVRKIRFAPGKGNQKLIAM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MGSITCIAWKGDTLVLGDMDGNLNFWDLKGRVSRGIPTHRSWVRKIRFAPGKGNQKLIAM
460 470 480 490 500 510
770 780 790 800 810 820
pF1KA1 YNDGAEVWDTKEVQMVSSLRSGRNVTFRILDVDWCTSDKVILASDDGCIRVLEMSMKSAC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 YNDGAEVWDTKEVQMVSSLRSGRNVTFRILDVDWCTSDKVILASDDGCIRVLEMSMKSAC
520 530 540 550 560 570
830 840 850 860 870 880
pF1KA1 FRMDEQELTEPVWCPYLLVPRASLALKAFLLHQPWNGQYSLDISHVDYPENEEIKNLLQE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FRMDEQELTEPVWCPYLLVPRASLALKAFLLHQPWNGQYSLDISHVDYPENEEIKNLLQE
580 590 600 610 620 630
890 900 910 920 930 940
pF1KA1 QLNSLSNDIKKLLLDPEFTLLQRCLLVSRLYGDESELHFWTVAAHYLHSLSQEKSASTTA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QLNSLSNDIKKLLLDPEFTLLQRCLLVSRLYGDESELHFWTVAAHYLHSLSQEKSASTTA
640 650 660 670 680 690
950 960 970 980 990 1000
pF1KA1 PKEAAPRDKLSNPLDICYDVLCENAYFQKFQLERVNLQEVKRSTYDHTRKCTDQLLLLGQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PKEAAPRDKLSNPLDICYDVLCENAYFQKFQLERVNLQEVKRSTYDHTRKCTDQLLLLGQ
700 710 720 730 740 750
1010 1020 1030 1040 1050 1060
pF1KA1 TDRAVQLLLETSADNQHYYCDSLKACLVTTVTSSGPSQSTIKLVATNMIANGKLAEGVQL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TDRAVQLLLETSADNQHYYCDSLKACLVTTVTSSGPSQSTIKLVATNMIANGKLAEGVQL
760 770 780 790 800 810
1070 1080 1090 1100 1110 1120
pF1KA1 LCLIDKAADACRYLQTYGEWNRAAWLAKVRLNPEECADVLRRWVDHLCSPQVNQKSKALL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LCLIDKAADACRYLQTYGEWNRAAWLAKVRLNPEECADVLRRWVDHLCSPQVNQKSKALL
820 830 840 850 860 870
1130 1140 1150 1160 1170 1180
pF1KA1 VLLSLGCFFSVAETLHSMRYFDRAALFVEACLKYGAFEVTEDTEKLITAIYADYARSLKN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VLLSLGCFFSVAETLHSMRYFDRAALFVEACLKYGAFEVTEDTEKLITAIYADYARSLKN
880 890 900 910 920 930
1190 1200 1210 1220
pF1KA1 LGFKQGAVLFASKAGAAGKDLLNELESPKEEPIEE
:::::::::::::::::::::::::::::::::::
XP_016 LGFKQGAVLFASKAGAAGKDLLNELESPKEEPIEE
940 950 960
>>XP_016871888 (OMIM: 606417,614858) PREDICTED: WD repea (795 aa)
initn: 5240 init1: 5240 opt: 5240 Z-score: 5570.4 bits: 1042.2 E(85289): 0
Smith-Waterman score: 5240; 100.0% identity (100.0% similar) in 795 aa overlap (430-1224:1-795)
400 410 420 430 440 450
pF1KA1 GVSPLYSPVSFCGIPVGVLQNKLPDLSLDNMIGQSAIAGEEHPRGSILREVHLKFLLTGL
::::::::::::::::::::::::::::::
XP_016 MIGQSAIAGEEHPRGSILREVHLKFLLTGL
10 20 30
460 470 480 490 500 510
pF1KA1 LSGLPAPQFAIRMCPPLTTKNIKMYQPLLAVGTSNGSVLVYHLTSGLLHKELSIHSCEVK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LSGLPAPQFAIRMCPPLTTKNIKMYQPLLAVGTSNGSVLVYHLTSGLLHKELSIHSCEVK
40 50 60 70 80 90
520 530 540 550 560 570
pF1KA1 GIEWTSLTSFLSFATSTPNNMGLVRNELQLVDLPTGRSIAFRGERGNDESAIEMIKVSHL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GIEWTSLTSFLSFATSTPNNMGLVRNELQLVDLPTGRSIAFRGERGNDESAIEMIKVSHL
100 110 120 130 140 150
580 590 600 610 620 630
pF1KA1 KQYLAVVFRDKPLELWDVRTCTLLREMSKNFPTITALEWSPSHNLKSLRKKQLATREAMA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KQYLAVVFRDKPLELWDVRTCTLLREMSKNFPTITALEWSPSHNLKSLRKKQLATREAMA
160 170 180 190 200 210
640 650 660 670 680 690
pF1KA1 RQTVVSDTELSIVESSVISLLQEAESKSELSQNISAREHFVFTDIDGQVYHLTVEGNSVK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RQTVVSDTELSIVESSVISLLQEAESKSELSQNISAREHFVFTDIDGQVYHLTVEGNSVK
220 230 240 250 260 270
700 710 720 730 740 750
pF1KA1 DSARIPPDGSMGSITCIAWKGDTLVLGDMDGNLNFWDLKGRVSRGIPTHRSWVRKIRFAP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DSARIPPDGSMGSITCIAWKGDTLVLGDMDGNLNFWDLKGRVSRGIPTHRSWVRKIRFAP
280 290 300 310 320 330
760 770 780 790 800 810
pF1KA1 GKGNQKLIAMYNDGAEVWDTKEVQMVSSLRSGRNVTFRILDVDWCTSDKVILASDDGCIR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GKGNQKLIAMYNDGAEVWDTKEVQMVSSLRSGRNVTFRILDVDWCTSDKVILASDDGCIR
340 350 360 370 380 390
820 830 840 850 860 870
pF1KA1 VLEMSMKSACFRMDEQELTEPVWCPYLLVPRASLALKAFLLHQPWNGQYSLDISHVDYPE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VLEMSMKSACFRMDEQELTEPVWCPYLLVPRASLALKAFLLHQPWNGQYSLDISHVDYPE
400 410 420 430 440 450
880 890 900 910 920 930
pF1KA1 NEEIKNLLQEQLNSLSNDIKKLLLDPEFTLLQRCLLVSRLYGDESELHFWTVAAHYLHSL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NEEIKNLLQEQLNSLSNDIKKLLLDPEFTLLQRCLLVSRLYGDESELHFWTVAAHYLHSL
460 470 480 490 500 510
940 950 960 970 980 990
pF1KA1 SQEKSASTTAPKEAAPRDKLSNPLDICYDVLCENAYFQKFQLERVNLQEVKRSTYDHTRK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SQEKSASTTAPKEAAPRDKLSNPLDICYDVLCENAYFQKFQLERVNLQEVKRSTYDHTRK
520 530 540 550 560 570
1000 1010 1020 1030 1040 1050
pF1KA1 CTDQLLLLGQTDRAVQLLLETSADNQHYYCDSLKACLVTTVTSSGPSQSTIKLVATNMIA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 CTDQLLLLGQTDRAVQLLLETSADNQHYYCDSLKACLVTTVTSSGPSQSTIKLVATNMIA
580 590 600 610 620 630
1060 1070 1080 1090 1100 1110
pF1KA1 NGKLAEGVQLLCLIDKAADACRYLQTYGEWNRAAWLAKVRLNPEECADVLRRWVDHLCSP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NGKLAEGVQLLCLIDKAADACRYLQTYGEWNRAAWLAKVRLNPEECADVLRRWVDHLCSP
640 650 660 670 680 690
1120 1130 1140 1150 1160 1170
pF1KA1 QVNQKSKALLVLLSLGCFFSVAETLHSMRYFDRAALFVEACLKYGAFEVTEDTEKLITAI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QVNQKSKALLVLLSLGCFFSVAETLHSMRYFDRAALFVEACLKYGAFEVTEDTEKLITAI
700 710 720 730 740 750
1180 1190 1200 1210 1220
pF1KA1 YADYARSLKNLGFKQGAVLFASKAGAAGKDLLNELESPKEEPIEE
:::::::::::::::::::::::::::::::::::::::::::::
XP_016 YADYARSLKNLGFKQGAVLFASKAGAAGKDLLNELESPKEEPIEE
760 770 780 790
>>XP_016871889 (OMIM: 606417,614858) PREDICTED: WD repea (781 aa)
initn: 5204 init1: 5204 opt: 5204 Z-score: 5532.2 bits: 1035.1 E(85289): 0
Smith-Waterman score: 5204; 100.0% identity (100.0% similar) in 781 aa overlap (1-781:1-781)
10 20 30 40 50 60
pF1KA1 MLPYTVNFKVSARTLTGALNAHNKAAVDWGWQGLIAYGCHSLVVVIDSITAQTLQVLEKH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MLPYTVNFKVSARTLTGALNAHNKAAVDWGWQGLIAYGCHSLVVVIDSITAQTLQVLEKH
10 20 30 40 50 60
70 80 90 100 110 120
pF1KA1 KADVVKVKWARENYHHNIGSPYCLRLASADVNGKIIVWDVAAGVAQCEIQEHAKPIQDVQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KADVVKVKWARENYHHNIGSPYCLRLASADVNGKIIVWDVAAGVAQCEIQEHAKPIQDVQ
70 80 90 100 110 120
130 140 150 160 170 180
pF1KA1 WLWNQDASRDLLLAIHPPNYIVLWNADTGTKLWKKSYADNILSFSFDPFDPSHLTLLTSE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 WLWNQDASRDLLLAIHPPNYIVLWNADTGTKLWKKSYADNILSFSFDPFDPSHLTLLTSE
130 140 150 160 170 180
190 200 210 220 230 240
pF1KA1 GIVFISDFSPSKPPSGPGKKVYISSPHSSPAHNKLATATGAKKALNKVKILITQEKPSAE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GIVFISDFSPSKPPSGPGKKVYISSPHSSPAHNKLATATGAKKALNKVKILITQEKPSAE
190 200 210 220 230 240
250 260 270 280 290 300
pF1KA1 FITLNDCLQLAYLPSKRNHMLLLYPREILILDLEVNQTVGVIAIERTGVPFLQVIPCFQR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FITLNDCLQLAYLPSKRNHMLLLYPREILILDLEVNQTVGVIAIERTGVPFLQVIPCFQR
250 260 270 280 290 300
310 320 330 340 350 360
pF1KA1 DGLFCLHENGCITLRVRRSYNNIFTTSNEEPDPDPVQELTYDLRSQCDAIRVTKTVRPFS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DGLFCLHENGCITLRVRRSYNNIFTTSNEEPDPDPVQELTYDLRSQCDAIRVTKTVRPFS
310 320 330 340 350 360
370 380 390 400 410 420
pF1KA1 MVCCPVNENAAALVVSDGRVMIWELKSAVCNRNSRNSSSGVSPLYSPVSFCGIPVGVLQN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MVCCPVNENAAALVVSDGRVMIWELKSAVCNRNSRNSSSGVSPLYSPVSFCGIPVGVLQN
370 380 390 400 410 420
430 440 450 460 470 480
pF1KA1 KLPDLSLDNMIGQSAIAGEEHPRGSILREVHLKFLLTGLLSGLPAPQFAIRMCPPLTTKN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KLPDLSLDNMIGQSAIAGEEHPRGSILREVHLKFLLTGLLSGLPAPQFAIRMCPPLTTKN
430 440 450 460 470 480
490 500 510 520 530 540
pF1KA1 IKMYQPLLAVGTSNGSVLVYHLTSGLLHKELSIHSCEVKGIEWTSLTSFLSFATSTPNNM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IKMYQPLLAVGTSNGSVLVYHLTSGLLHKELSIHSCEVKGIEWTSLTSFLSFATSTPNNM
490 500 510 520 530 540
550 560 570 580 590 600
pF1KA1 GLVRNELQLVDLPTGRSIAFRGERGNDESAIEMIKVSHLKQYLAVVFRDKPLELWDVRTC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GLVRNELQLVDLPTGRSIAFRGERGNDESAIEMIKVSHLKQYLAVVFRDKPLELWDVRTC
550 560 570 580 590 600
610 620 630 640 650 660
pF1KA1 TLLREMSKNFPTITALEWSPSHNLKSLRKKQLATREAMARQTVVSDTELSIVESSVISLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TLLREMSKNFPTITALEWSPSHNLKSLRKKQLATREAMARQTVVSDTELSIVESSVISLL
610 620 630 640 650 660
670 680 690 700 710 720
pF1KA1 QEAESKSELSQNISAREHFVFTDIDGQVYHLTVEGNSVKDSARIPPDGSMGSITCIAWKG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QEAESKSELSQNISAREHFVFTDIDGQVYHLTVEGNSVKDSARIPPDGSMGSITCIAWKG
670 680 690 700 710 720
730 740 750 760 770 780
pF1KA1 DTLVLGDMDGNLNFWDLKGRVSRGIPTHRSWVRKIRFAPGKGNQKLIAMYNDGAEVWDTK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DTLVLGDMDGNLNFWDLKGRVSRGIPTHRSWVRKIRFAPGKGNQKLIAMYNDGAEVWDTK
730 740 750 760 770 780
790 800 810 820 830 840
pF1KA1 EVQMVSSLRSGRNVTFRILDVDWCTSDKVILASDDGCIRVLEMSMKSACFRMDEQELTEP
:
XP_016 E
>>XP_005270021 (OMIM: 606417,614858) PREDICTED: WD repea (753 aa)
initn: 4968 init1: 4968 opt: 4968 Z-score: 5281.5 bits: 988.7 E(85289): 0
Smith-Waterman score: 4968; 100.0% identity (100.0% similar) in 753 aa overlap (472-1224:1-753)
450 460 470 480 490 500
pF1KA1 PRGSILREVHLKFLLTGLLSGLPAPQFAIRMCPPLTTKNIKMYQPLLAVGTSNGSVLVYH
::::::::::::::::::::::::::::::
XP_005 MCPPLTTKNIKMYQPLLAVGTSNGSVLVYH
10 20 30
510 520 530 540 550 560
pF1KA1 LTSGLLHKELSIHSCEVKGIEWTSLTSFLSFATSTPNNMGLVRNELQLVDLPTGRSIAFR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LTSGLLHKELSIHSCEVKGIEWTSLTSFLSFATSTPNNMGLVRNELQLVDLPTGRSIAFR
40 50 60 70 80 90
570 580 590 600 610 620
pF1KA1 GERGNDESAIEMIKVSHLKQYLAVVFRDKPLELWDVRTCTLLREMSKNFPTITALEWSPS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 GERGNDESAIEMIKVSHLKQYLAVVFRDKPLELWDVRTCTLLREMSKNFPTITALEWSPS
100 110 120 130 140 150
630 640 650 660 670 680
pF1KA1 HNLKSLRKKQLATREAMARQTVVSDTELSIVESSVISLLQEAESKSELSQNISAREHFVF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 HNLKSLRKKQLATREAMARQTVVSDTELSIVESSVISLLQEAESKSELSQNISAREHFVF
160 170 180 190 200 210
690 700 710 720 730 740
pF1KA1 TDIDGQVYHLTVEGNSVKDSARIPPDGSMGSITCIAWKGDTLVLGDMDGNLNFWDLKGRV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 TDIDGQVYHLTVEGNSVKDSARIPPDGSMGSITCIAWKGDTLVLGDMDGNLNFWDLKGRV
220 230 240 250 260 270
750 760 770 780 790 800
pF1KA1 SRGIPTHRSWVRKIRFAPGKGNQKLIAMYNDGAEVWDTKEVQMVSSLRSGRNVTFRILDV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SRGIPTHRSWVRKIRFAPGKGNQKLIAMYNDGAEVWDTKEVQMVSSLRSGRNVTFRILDV
280 290 300 310 320 330
810 820 830 840 850 860
pF1KA1 DWCTSDKVILASDDGCIRVLEMSMKSACFRMDEQELTEPVWCPYLLVPRASLALKAFLLH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 DWCTSDKVILASDDGCIRVLEMSMKSACFRMDEQELTEPVWCPYLLVPRASLALKAFLLH
340 350 360 370 380 390
870 880 890 900 910 920
pF1KA1 QPWNGQYSLDISHVDYPENEEIKNLLQEQLNSLSNDIKKLLLDPEFTLLQRCLLVSRLYG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 QPWNGQYSLDISHVDYPENEEIKNLLQEQLNSLSNDIKKLLLDPEFTLLQRCLLVSRLYG
400 410 420 430 440 450
930 940 950 960 970 980
pF1KA1 DESELHFWTVAAHYLHSLSQEKSASTTAPKEAAPRDKLSNPLDICYDVLCENAYFQKFQL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 DESELHFWTVAAHYLHSLSQEKSASTTAPKEAAPRDKLSNPLDICYDVLCENAYFQKFQL
460 470 480 490 500 510
990 1000 1010 1020 1030 1040
pF1KA1 ERVNLQEVKRSTYDHTRKCTDQLLLLGQTDRAVQLLLETSADNQHYYCDSLKACLVTTVT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 ERVNLQEVKRSTYDHTRKCTDQLLLLGQTDRAVQLLLETSADNQHYYCDSLKACLVTTVT
520 530 540 550 560 570
1050 1060 1070 1080 1090 1100
pF1KA1 SSGPSQSTIKLVATNMIANGKLAEGVQLLCLIDKAADACRYLQTYGEWNRAAWLAKVRLN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SSGPSQSTIKLVATNMIANGKLAEGVQLLCLIDKAADACRYLQTYGEWNRAAWLAKVRLN
580 590 600 610 620 630
1110 1120 1130 1140 1150 1160
pF1KA1 PEECADVLRRWVDHLCSPQVNQKSKALLVLLSLGCFFSVAETLHSMRYFDRAALFVEACL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 PEECADVLRRWVDHLCSPQVNQKSKALLVLLSLGCFFSVAETLHSMRYFDRAALFVEACL
640 650 660 670 680 690
1170 1180 1190 1200 1210 1220
pF1KA1 KYGAFEVTEDTEKLITAIYADYARSLKNLGFKQGAVLFASKAGAAGKDLLNELESPKEEP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 KYGAFEVTEDTEKLITAIYADYARSLKNLGFKQGAVLFASKAGAAGKDLLNELESPKEEP
700 710 720 730 740 750
pF1KA1 IEE
:::
XP_005 IEE
1224 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Thu Nov 3 10:56:00 2016 done: Thu Nov 3 10:56:02 2016
Total Scan time: 13.050 Total Display time: 0.310
Function used was FASTA [36.3.4 Apr, 2011]