Result of FASTA (omim) for pF1KSDA1972
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KSDA1972, 576 aa
  1>>>pF1KSDA1972 576 - 576 aa - 576 aa
Library: /omim/omim.rfq.tfa
  60827320 residues in 85289 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 6.0640+/-0.000374; mu= 16.4129+/- 0.023
 mean_var=120.0675+/-25.287, 0's: 0 Z-trim(116.1): 116  B-trim: 1252 in 1/52
 Lambda= 0.117047
 statistics sampled from 26937 (27075) to 26937 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.685), E-opt: 0.2 (0.317), width:  16
 Scan time: 10.060

The best scores are:                                      opt bits E(85289)
NP_001292092 (OMIM: 616585,616723) RING finger and ( 576) 3921 673.7 4.6e-193
XP_005256277 (OMIM: 616585,616723) PREDICTED: RING ( 576) 3921 673.7 4.6e-193
NP_588609 (OMIM: 616585,616723) RING finger and SP ( 576) 3921 673.7 4.6e-193
NP_001292093 (OMIM: 616585,616723) RING finger and ( 576) 3921 673.7 4.6e-193
XP_011521729 (OMIM: 616585,616723) PREDICTED: RING ( 607) 3140 541.8 2.4e-153
XP_011521732 (OMIM: 616585,616723) PREDICTED: RING ( 607) 3140 541.8 2.4e-153
XP_011521730 (OMIM: 616585,616723) PREDICTED: RING ( 607) 3140 541.8 2.4e-153
XP_016879333 (OMIM: 616585,616723) PREDICTED: RING ( 452) 3080 531.5 2.2e-150
NP_001292111 (OMIM: 616585,616723) RING finger and ( 117)  780 142.6 6.8e-34
XP_016862507 (OMIM: 614472) PREDICTED: E3 ubiquiti (1314)  320 65.9 9.2e-10
XP_011532297 (OMIM: 614472) PREDICTED: E3 ubiquiti (1314)  320 65.9 9.2e-10
NP_071347 (OMIM: 614472) E3 ubiquitin-protein liga (1314)  320 65.9 9.2e-10
XP_006713348 (OMIM: 614472) PREDICTED: E3 ubiquiti (1314)  320 65.9 9.2e-10
XP_006711872 (OMIM: 180902,600996,604772) PREDICTE (2735)  246 53.7 8.9e-06
XP_006711871 (OMIM: 180902,600996,604772) PREDICTE (4906)  246 54.0 1.4e-05
XP_006711873 (OMIM: 180902,600996,604772) PREDICTE (4954)  246 54.0 1.4e-05
XP_006711870 (OMIM: 180902,600996,604772) PREDICTE (4965)  246 54.0 1.4e-05
NP_001026 (OMIM: 180902,600996,604772) ryanodine r (4967)  246 54.0 1.4e-05
XP_006711869 (OMIM: 180902,600996,604772) PREDICTE (4973)  246 54.0 1.4e-05
XP_006711868 (OMIM: 180902,600996,604772) PREDICTE (4975)  246 54.0 1.4e-05
XP_006711867 (OMIM: 180902,600996,604772) PREDICTE (4977)  246 54.0 1.4e-05
XP_016857517 (OMIM: 180902,600996,604772) PREDICTE (4978)  246 54.0 1.4e-05
XP_006711866 (OMIM: 180902,600996,604772) PREDICTE (4984)  246 54.0 1.4e-05
XP_006711865 (OMIM: 180902,600996,604772) PREDICTE (4985)  246 54.0 1.4e-05
XP_011525507 (OMIM: 117000,145600,180901,255310,25 (5009)  240 53.0 2.8e-05
XP_006723382 (OMIM: 117000,145600,180901,255310,25 (5027)  240 53.0 2.8e-05
XP_006723380 (OMIM: 117000,145600,180901,255310,25 (5032)  240 53.0 2.8e-05
NP_001036188 (OMIM: 117000,145600,180901,255310,25 (5033)  240 53.0 2.8e-05
NP_000531 (OMIM: 117000,145600,180901,255310,25532 (5038)  240 53.0 2.8e-05
XP_016877966 (OMIM: 180903) PREDICTED: ryanodine r (3855)  214 48.5 0.00048
XP_016877965 (OMIM: 180903) PREDICTED: ryanodine r (4830)  214 48.6 0.00057
XP_016877964 (OMIM: 180903) PREDICTED: ryanodine r (4837)  214 48.6 0.00057
XP_016877963 (OMIM: 180903) PREDICTED: ryanodine r (4859)  214 48.6 0.00057
XP_011520182 (OMIM: 180903) PREDICTED: ryanodine r (4859)  214 48.6 0.00057
XP_016877962 (OMIM: 180903) PREDICTED: ryanodine r (4860)  214 48.6 0.00057
XP_016877961 (OMIM: 180903) PREDICTED: ryanodine r (4864)  214 48.6 0.00057
XP_016877959 (OMIM: 180903) PREDICTED: ryanodine r (4865)  214 48.6 0.00057
XP_016877960 (OMIM: 180903) PREDICTED: ryanodine r (4865)  214 48.6 0.00057
XP_016877958 (OMIM: 180903) PREDICTED: ryanodine r (4865)  214 48.6 0.00057
NP_001230925 (OMIM: 180903) ryanodine receptor 3 i (4865)  214 48.6 0.00057
XP_016877957 (OMIM: 180903) PREDICTED: ryanodine r (4866)  214 48.6 0.00057
NP_001027 (OMIM: 180903) ryanodine receptor 3 isof (4870)  214 48.6 0.00057
XP_005249090 (OMIM: 610082) PREDICTED: E3 ubiquiti ( 264)  184 42.3  0.0024
XP_005249089 (OMIM: 610082) PREDICTED: E3 ubiquiti ( 390)  184 42.5  0.0032
NP_037394 (OMIM: 610082) E3 ubiquitin-protein liga ( 445)  184 42.5  0.0035


>>NP_001292092 (OMIM: 616585,616723) RING finger and SPR  (576 aa)
 initn: 3921 init1: 3921 opt: 3921  Z-score: 3587.2  bits: 673.7 E(85289): 4.6e-193
Smith-Waterman score: 3921; 100.0% identity (100.0% similar) in 576 aa overlap (1-576:1-576)

               10        20        30        40        50        60
pF1KSD MIVFGWAVFLASRSLGQGLLLTLEEHIAHFLGTGGAATTMGNSCICRDDSGTDDSVDTQQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MIVFGWAVFLASRSLGQGLLLTLEEHIAHFLGTGGAATTMGNSCICRDDSGTDDSVDTQQ
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KSD QQAENSAVPTADTRSQPRDPVRPPRRGRGPHEPRRKKQNVDGLVLDTLAVIRTLVDNDQE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QQAENSAVPTADTRSQPRDPVRPPRRGRGPHEPRRKKQNVDGLVLDTLAVIRTLVDNDQE
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KSD PPYSMITLHEMAETDEGWLDVVQSLIRVIPLEDPLGPAVITLLLDECPLPTKDALQKLTE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PPYSMITLHEMAETDEGWLDVVQSLIRVIPLEDPLGPAVITLLLDECPLPTKDALQKLTE
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KSD ILNLNGEVACQDSSHPAKHRNTSAVLGCLAEKLAGPASIGLLSPGILEYLLQCLKLQSHP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ILNLNGEVACQDSSHPAKHRNTSAVLGCLAEKLAGPASIGLLSPGILEYLLQCLKLQSHP
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KSD TVMLFALIALEKFAQTSENKLTISESSISDRLVTLESWANDPDYLKRQVGFCAQWSLDNL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TVMLFALIALEKFAQTSENKLTISESSISDRLVTLESWANDPDYLKRQVGFCAQWSLDNL
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KSD FLKEGRQLTYEKVNLSSIRAMLNSNDVSEYLKISPHGLEARCDASSFESVRCTFCVDAGV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FLKEGRQLTYEKVNLSSIRAMLNSNDVSEYLKISPHGLEARCDASSFESVRCTFCVDAGV
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KSD WYYEVTVVTSGVMQIGWATRDSKFLNHEGYGIGDDEYSCAYDGCRQLIWYNARSKPHIHP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 WYYEVTVVTSGVMQIGWATRDSKFLNHEGYGIGDDEYSCAYDGCRQLIWYNARSKPHIHP
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KSD CWKEGDTVGFLLDLNEKQMIFFLNGNQLPPEKQVFSSTVSGFFAAASFMSYQQCEFNFGA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 CWKEGDTVGFLLDLNEKQMIFFLNGNQLPPEKQVFSSTVSGFFAAASFMSYQQCEFNFGA
              430       440       450       460       470       480

              490       500       510       520       530       540
pF1KSD KPFKYPPSMKFSTFNDYAFLTAEEKIILPRHRRLALLKQVSIRENCCSLCCDEVADTQLK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KPFKYPPSMKFSTFNDYAFLTAEEKIILPRHRRLALLKQVSIRENCCSLCCDEVADTQLK
              490       500       510       520       530       540

              550       560       570      
pF1KSD PCGHSDLCMDCALQLETCPLCRKEIVSRIRQISHIS
       ::::::::::::::::::::::::::::::::::::
NP_001 PCGHSDLCMDCALQLETCPLCRKEIVSRIRQISHIS
              550       560       570      

>>XP_005256277 (OMIM: 616585,616723) PREDICTED: RING fin  (576 aa)
 initn: 3921 init1: 3921 opt: 3921  Z-score: 3587.2  bits: 673.7 E(85289): 4.6e-193
Smith-Waterman score: 3921; 100.0% identity (100.0% similar) in 576 aa overlap (1-576:1-576)

               10        20        30        40        50        60
pF1KSD MIVFGWAVFLASRSLGQGLLLTLEEHIAHFLGTGGAATTMGNSCICRDDSGTDDSVDTQQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MIVFGWAVFLASRSLGQGLLLTLEEHIAHFLGTGGAATTMGNSCICRDDSGTDDSVDTQQ
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KSD QQAENSAVPTADTRSQPRDPVRPPRRGRGPHEPRRKKQNVDGLVLDTLAVIRTLVDNDQE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 QQAENSAVPTADTRSQPRDPVRPPRRGRGPHEPRRKKQNVDGLVLDTLAVIRTLVDNDQE
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KSD PPYSMITLHEMAETDEGWLDVVQSLIRVIPLEDPLGPAVITLLLDECPLPTKDALQKLTE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 PPYSMITLHEMAETDEGWLDVVQSLIRVIPLEDPLGPAVITLLLDECPLPTKDALQKLTE
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KSD ILNLNGEVACQDSSHPAKHRNTSAVLGCLAEKLAGPASIGLLSPGILEYLLQCLKLQSHP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 ILNLNGEVACQDSSHPAKHRNTSAVLGCLAEKLAGPASIGLLSPGILEYLLQCLKLQSHP
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KSD TVMLFALIALEKFAQTSENKLTISESSISDRLVTLESWANDPDYLKRQVGFCAQWSLDNL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 TVMLFALIALEKFAQTSENKLTISESSISDRLVTLESWANDPDYLKRQVGFCAQWSLDNL
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KSD FLKEGRQLTYEKVNLSSIRAMLNSNDVSEYLKISPHGLEARCDASSFESVRCTFCVDAGV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 FLKEGRQLTYEKVNLSSIRAMLNSNDVSEYLKISPHGLEARCDASSFESVRCTFCVDAGV
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KSD WYYEVTVVTSGVMQIGWATRDSKFLNHEGYGIGDDEYSCAYDGCRQLIWYNARSKPHIHP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 WYYEVTVVTSGVMQIGWATRDSKFLNHEGYGIGDDEYSCAYDGCRQLIWYNARSKPHIHP
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KSD CWKEGDTVGFLLDLNEKQMIFFLNGNQLPPEKQVFSSTVSGFFAAASFMSYQQCEFNFGA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 CWKEGDTVGFLLDLNEKQMIFFLNGNQLPPEKQVFSSTVSGFFAAASFMSYQQCEFNFGA
              430       440       450       460       470       480

              490       500       510       520       530       540
pF1KSD KPFKYPPSMKFSTFNDYAFLTAEEKIILPRHRRLALLKQVSIRENCCSLCCDEVADTQLK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 KPFKYPPSMKFSTFNDYAFLTAEEKIILPRHRRLALLKQVSIRENCCSLCCDEVADTQLK
              490       500       510       520       530       540

              550       560       570      
pF1KSD PCGHSDLCMDCALQLETCPLCRKEIVSRIRQISHIS
       ::::::::::::::::::::::::::::::::::::
XP_005 PCGHSDLCMDCALQLETCPLCRKEIVSRIRQISHIS
              550       560       570      

>>NP_588609 (OMIM: 616585,616723) RING finger and SPRY d  (576 aa)
 initn: 3921 init1: 3921 opt: 3921  Z-score: 3587.2  bits: 673.7 E(85289): 4.6e-193
Smith-Waterman score: 3921; 100.0% identity (100.0% similar) in 576 aa overlap (1-576:1-576)

               10        20        30        40        50        60
pF1KSD MIVFGWAVFLASRSLGQGLLLTLEEHIAHFLGTGGAATTMGNSCICRDDSGTDDSVDTQQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_588 MIVFGWAVFLASRSLGQGLLLTLEEHIAHFLGTGGAATTMGNSCICRDDSGTDDSVDTQQ
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KSD QQAENSAVPTADTRSQPRDPVRPPRRGRGPHEPRRKKQNVDGLVLDTLAVIRTLVDNDQE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_588 QQAENSAVPTADTRSQPRDPVRPPRRGRGPHEPRRKKQNVDGLVLDTLAVIRTLVDNDQE
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KSD PPYSMITLHEMAETDEGWLDVVQSLIRVIPLEDPLGPAVITLLLDECPLPTKDALQKLTE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_588 PPYSMITLHEMAETDEGWLDVVQSLIRVIPLEDPLGPAVITLLLDECPLPTKDALQKLTE
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KSD ILNLNGEVACQDSSHPAKHRNTSAVLGCLAEKLAGPASIGLLSPGILEYLLQCLKLQSHP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_588 ILNLNGEVACQDSSHPAKHRNTSAVLGCLAEKLAGPASIGLLSPGILEYLLQCLKLQSHP
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KSD TVMLFALIALEKFAQTSENKLTISESSISDRLVTLESWANDPDYLKRQVGFCAQWSLDNL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_588 TVMLFALIALEKFAQTSENKLTISESSISDRLVTLESWANDPDYLKRQVGFCAQWSLDNL
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KSD FLKEGRQLTYEKVNLSSIRAMLNSNDVSEYLKISPHGLEARCDASSFESVRCTFCVDAGV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_588 FLKEGRQLTYEKVNLSSIRAMLNSNDVSEYLKISPHGLEARCDASSFESVRCTFCVDAGV
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KSD WYYEVTVVTSGVMQIGWATRDSKFLNHEGYGIGDDEYSCAYDGCRQLIWYNARSKPHIHP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_588 WYYEVTVVTSGVMQIGWATRDSKFLNHEGYGIGDDEYSCAYDGCRQLIWYNARSKPHIHP
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KSD CWKEGDTVGFLLDLNEKQMIFFLNGNQLPPEKQVFSSTVSGFFAAASFMSYQQCEFNFGA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_588 CWKEGDTVGFLLDLNEKQMIFFLNGNQLPPEKQVFSSTVSGFFAAASFMSYQQCEFNFGA
              430       440       450       460       470       480

              490       500       510       520       530       540
pF1KSD KPFKYPPSMKFSTFNDYAFLTAEEKIILPRHRRLALLKQVSIRENCCSLCCDEVADTQLK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_588 KPFKYPPSMKFSTFNDYAFLTAEEKIILPRHRRLALLKQVSIRENCCSLCCDEVADTQLK
              490       500       510       520       530       540

              550       560       570      
pF1KSD PCGHSDLCMDCALQLETCPLCRKEIVSRIRQISHIS
       ::::::::::::::::::::::::::::::::::::
NP_588 PCGHSDLCMDCALQLETCPLCRKEIVSRIRQISHIS
              550       560       570      

>>NP_001292093 (OMIM: 616585,616723) RING finger and SPR  (576 aa)
 initn: 3921 init1: 3921 opt: 3921  Z-score: 3587.2  bits: 673.7 E(85289): 4.6e-193
Smith-Waterman score: 3921; 100.0% identity (100.0% similar) in 576 aa overlap (1-576:1-576)

               10        20        30        40        50        60
pF1KSD MIVFGWAVFLASRSLGQGLLLTLEEHIAHFLGTGGAATTMGNSCICRDDSGTDDSVDTQQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MIVFGWAVFLASRSLGQGLLLTLEEHIAHFLGTGGAATTMGNSCICRDDSGTDDSVDTQQ
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KSD QQAENSAVPTADTRSQPRDPVRPPRRGRGPHEPRRKKQNVDGLVLDTLAVIRTLVDNDQE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QQAENSAVPTADTRSQPRDPVRPPRRGRGPHEPRRKKQNVDGLVLDTLAVIRTLVDNDQE
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KSD PPYSMITLHEMAETDEGWLDVVQSLIRVIPLEDPLGPAVITLLLDECPLPTKDALQKLTE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PPYSMITLHEMAETDEGWLDVVQSLIRVIPLEDPLGPAVITLLLDECPLPTKDALQKLTE
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KSD ILNLNGEVACQDSSHPAKHRNTSAVLGCLAEKLAGPASIGLLSPGILEYLLQCLKLQSHP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ILNLNGEVACQDSSHPAKHRNTSAVLGCLAEKLAGPASIGLLSPGILEYLLQCLKLQSHP
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KSD TVMLFALIALEKFAQTSENKLTISESSISDRLVTLESWANDPDYLKRQVGFCAQWSLDNL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TVMLFALIALEKFAQTSENKLTISESSISDRLVTLESWANDPDYLKRQVGFCAQWSLDNL
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KSD FLKEGRQLTYEKVNLSSIRAMLNSNDVSEYLKISPHGLEARCDASSFESVRCTFCVDAGV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FLKEGRQLTYEKVNLSSIRAMLNSNDVSEYLKISPHGLEARCDASSFESVRCTFCVDAGV
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KSD WYYEVTVVTSGVMQIGWATRDSKFLNHEGYGIGDDEYSCAYDGCRQLIWYNARSKPHIHP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 WYYEVTVVTSGVMQIGWATRDSKFLNHEGYGIGDDEYSCAYDGCRQLIWYNARSKPHIHP
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KSD CWKEGDTVGFLLDLNEKQMIFFLNGNQLPPEKQVFSSTVSGFFAAASFMSYQQCEFNFGA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 CWKEGDTVGFLLDLNEKQMIFFLNGNQLPPEKQVFSSTVSGFFAAASFMSYQQCEFNFGA
              430       440       450       460       470       480

              490       500       510       520       530       540
pF1KSD KPFKYPPSMKFSTFNDYAFLTAEEKIILPRHRRLALLKQVSIRENCCSLCCDEVADTQLK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KPFKYPPSMKFSTFNDYAFLTAEEKIILPRHRRLALLKQVSIRENCCSLCCDEVADTQLK
              490       500       510       520       530       540

              550       560       570      
pF1KSD PCGHSDLCMDCALQLETCPLCRKEIVSRIRQISHIS
       ::::::::::::::::::::::::::::::::::::
NP_001 PCGHSDLCMDCALQLETCPLCRKEIVSRIRQISHIS
              550       560       570      

>>XP_011521729 (OMIM: 616585,616723) PREDICTED: RING fin  (607 aa)
 initn: 3901 init1: 3135 opt: 3140  Z-score: 2874.1  bits: 541.8 E(85289): 2.4e-153
Smith-Waterman score: 3843; 94.7% identity (94.9% similar) in 607 aa overlap (1-576:1-607)

               10        20        30        40        50        60
pF1KSD MIVFGWAVFLASRSLGQGLLLTLEEHIAHFLGTGGAATTMGNSCICRDDSGTDDSVDTQQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MIVFGWAVFLASRSLGQGLLLTLEEHIAHFLGTGGAATTMGNSCICRDDSGTDDSVDTQQ
               10        20        30        40        50        60

               70        80        90       100       110          
pF1KSD QQAENSAVPTADTRSQPRDPVRPPRRGRGPHEPRRKKQNVDGLVLDTLAVIRTLVD----
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::    
XP_011 QQAENSAVPTADTRSQPRDPVRPPRRGRGPHEPRRKKQNVDGLVLDTLAVIRTLVDKRKL
               70        80        90       100       110       120

                                   120       130       140         
pF1KSD ---------------------------NDQEPPYSMITLHEMAETDEGWLDVVQSLIRVI
                                  .::::::::::::::::::::::::::::::::
XP_011 QNEDAYIGPCFHKSSTGIVVSLPGISLSDQEPPYSMITLHEMAETDEGWLDVVQSLIRVI
              130       140       150       160       170       180

     150       160       170       180       190       200         
pF1KSD PLEDPLGPAVITLLLDECPLPTKDALQKLTEILNLNGEVACQDSSHPAKHRNTSAVLGCL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PLEDPLGPAVITLLLDECPLPTKDALQKLTEILNLNGEVACQDSSHPAKHRNTSAVLGCL
              190       200       210       220       230       240

     210       220       230       240       250       260         
pF1KSD AEKLAGPASIGLLSPGILEYLLQCLKLQSHPTVMLFALIALEKFAQTSENKLTISESSIS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AEKLAGPASIGLLSPGILEYLLQCLKLQSHPTVMLFALIALEKFAQTSENKLTISESSIS
              250       260       270       280       290       300

     270       280       290       300       310       320         
pF1KSD DRLVTLESWANDPDYLKRQVGFCAQWSLDNLFLKEGRQLTYEKVNLSSIRAMLNSNDVSE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DRLVTLESWANDPDYLKRQVGFCAQWSLDNLFLKEGRQLTYEKVNLSSIRAMLNSNDVSE
              310       320       330       340       350       360

     330       340       350       360       370       380         
pF1KSD YLKISPHGLEARCDASSFESVRCTFCVDAGVWYYEVTVVTSGVMQIGWATRDSKFLNHEG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 YLKISPHGLEARCDASSFESVRCTFCVDAGVWYYEVTVVTSGVMQIGWATRDSKFLNHEG
              370       380       390       400       410       420

     390       400       410       420       430       440         
pF1KSD YGIGDDEYSCAYDGCRQLIWYNARSKPHIHPCWKEGDTVGFLLDLNEKQMIFFLNGNQLP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 YGIGDDEYSCAYDGCRQLIWYNARSKPHIHPCWKEGDTVGFLLDLNEKQMIFFLNGNQLP
              430       440       450       460       470       480

     450       460       470       480       490       500         
pF1KSD PEKQVFSSTVSGFFAAASFMSYQQCEFNFGAKPFKYPPSMKFSTFNDYAFLTAEEKIILP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PEKQVFSSTVSGFFAAASFMSYQQCEFNFGAKPFKYPPSMKFSTFNDYAFLTAEEKIILP
              490       500       510       520       530       540

     510       520       530       540       550       560         
pF1KSD RHRRLALLKQVSIRENCCSLCCDEVADTQLKPCGHSDLCMDCALQLETCPLCRKEIVSRI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RHRRLALLKQVSIRENCCSLCCDEVADTQLKPCGHSDLCMDCALQLETCPLCRKEIVSRI
              550       560       570       580       590       600

     570      
pF1KSD RQISHIS
       :::::::
XP_011 RQISHIS
              

>>XP_011521732 (OMIM: 616585,616723) PREDICTED: RING fin  (607 aa)
 initn: 3901 init1: 3135 opt: 3140  Z-score: 2874.1  bits: 541.8 E(85289): 2.4e-153
Smith-Waterman score: 3843; 94.7% identity (94.9% similar) in 607 aa overlap (1-576:1-607)

               10        20        30        40        50        60
pF1KSD MIVFGWAVFLASRSLGQGLLLTLEEHIAHFLGTGGAATTMGNSCICRDDSGTDDSVDTQQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MIVFGWAVFLASRSLGQGLLLTLEEHIAHFLGTGGAATTMGNSCICRDDSGTDDSVDTQQ
               10        20        30        40        50        60

               70        80        90       100       110          
pF1KSD QQAENSAVPTADTRSQPRDPVRPPRRGRGPHEPRRKKQNVDGLVLDTLAVIRTLVD----
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::    
XP_011 QQAENSAVPTADTRSQPRDPVRPPRRGRGPHEPRRKKQNVDGLVLDTLAVIRTLVDKRKL
               70        80        90       100       110       120

                                   120       130       140         
pF1KSD ---------------------------NDQEPPYSMITLHEMAETDEGWLDVVQSLIRVI
                                  .::::::::::::::::::::::::::::::::
XP_011 QNEDAYIGPCFHKSSTGIVVSLPGISLSDQEPPYSMITLHEMAETDEGWLDVVQSLIRVI
              130       140       150       160       170       180

     150       160       170       180       190       200         
pF1KSD PLEDPLGPAVITLLLDECPLPTKDALQKLTEILNLNGEVACQDSSHPAKHRNTSAVLGCL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PLEDPLGPAVITLLLDECPLPTKDALQKLTEILNLNGEVACQDSSHPAKHRNTSAVLGCL
              190       200       210       220       230       240

     210       220       230       240       250       260         
pF1KSD AEKLAGPASIGLLSPGILEYLLQCLKLQSHPTVMLFALIALEKFAQTSENKLTISESSIS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AEKLAGPASIGLLSPGILEYLLQCLKLQSHPTVMLFALIALEKFAQTSENKLTISESSIS
              250       260       270       280       290       300

     270       280       290       300       310       320         
pF1KSD DRLVTLESWANDPDYLKRQVGFCAQWSLDNLFLKEGRQLTYEKVNLSSIRAMLNSNDVSE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DRLVTLESWANDPDYLKRQVGFCAQWSLDNLFLKEGRQLTYEKVNLSSIRAMLNSNDVSE
              310       320       330       340       350       360

     330       340       350       360       370       380         
pF1KSD YLKISPHGLEARCDASSFESVRCTFCVDAGVWYYEVTVVTSGVMQIGWATRDSKFLNHEG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 YLKISPHGLEARCDASSFESVRCTFCVDAGVWYYEVTVVTSGVMQIGWATRDSKFLNHEG
              370       380       390       400       410       420

     390       400       410       420       430       440         
pF1KSD YGIGDDEYSCAYDGCRQLIWYNARSKPHIHPCWKEGDTVGFLLDLNEKQMIFFLNGNQLP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 YGIGDDEYSCAYDGCRQLIWYNARSKPHIHPCWKEGDTVGFLLDLNEKQMIFFLNGNQLP
              430       440       450       460       470       480

     450       460       470       480       490       500         
pF1KSD PEKQVFSSTVSGFFAAASFMSYQQCEFNFGAKPFKYPPSMKFSTFNDYAFLTAEEKIILP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PEKQVFSSTVSGFFAAASFMSYQQCEFNFGAKPFKYPPSMKFSTFNDYAFLTAEEKIILP
              490       500       510       520       530       540

     510       520       530       540       550       560         
pF1KSD RHRRLALLKQVSIRENCCSLCCDEVADTQLKPCGHSDLCMDCALQLETCPLCRKEIVSRI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RHRRLALLKQVSIRENCCSLCCDEVADTQLKPCGHSDLCMDCALQLETCPLCRKEIVSRI
              550       560       570       580       590       600

     570      
pF1KSD RQISHIS
       :::::::
XP_011 RQISHIS
              

>>XP_011521730 (OMIM: 616585,616723) PREDICTED: RING fin  (607 aa)
 initn: 3901 init1: 3135 opt: 3140  Z-score: 2874.1  bits: 541.8 E(85289): 2.4e-153
Smith-Waterman score: 3843; 94.7% identity (94.9% similar) in 607 aa overlap (1-576:1-607)

               10        20        30        40        50        60
pF1KSD MIVFGWAVFLASRSLGQGLLLTLEEHIAHFLGTGGAATTMGNSCICRDDSGTDDSVDTQQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MIVFGWAVFLASRSLGQGLLLTLEEHIAHFLGTGGAATTMGNSCICRDDSGTDDSVDTQQ
               10        20        30        40        50        60

               70        80        90       100       110          
pF1KSD QQAENSAVPTADTRSQPRDPVRPPRRGRGPHEPRRKKQNVDGLVLDTLAVIRTLVD----
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::    
XP_011 QQAENSAVPTADTRSQPRDPVRPPRRGRGPHEPRRKKQNVDGLVLDTLAVIRTLVDKRKL
               70        80        90       100       110       120

                                   120       130       140         
pF1KSD ---------------------------NDQEPPYSMITLHEMAETDEGWLDVVQSLIRVI
                                  .::::::::::::::::::::::::::::::::
XP_011 QNEDAYIGPCFHKSSTGIVVSLPGISLSDQEPPYSMITLHEMAETDEGWLDVVQSLIRVI
              130       140       150       160       170       180

     150       160       170       180       190       200         
pF1KSD PLEDPLGPAVITLLLDECPLPTKDALQKLTEILNLNGEVACQDSSHPAKHRNTSAVLGCL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PLEDPLGPAVITLLLDECPLPTKDALQKLTEILNLNGEVACQDSSHPAKHRNTSAVLGCL
              190       200       210       220       230       240

     210       220       230       240       250       260         
pF1KSD AEKLAGPASIGLLSPGILEYLLQCLKLQSHPTVMLFALIALEKFAQTSENKLTISESSIS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AEKLAGPASIGLLSPGILEYLLQCLKLQSHPTVMLFALIALEKFAQTSENKLTISESSIS
              250       260       270       280       290       300

     270       280       290       300       310       320         
pF1KSD DRLVTLESWANDPDYLKRQVGFCAQWSLDNLFLKEGRQLTYEKVNLSSIRAMLNSNDVSE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DRLVTLESWANDPDYLKRQVGFCAQWSLDNLFLKEGRQLTYEKVNLSSIRAMLNSNDVSE
              310       320       330       340       350       360

     330       340       350       360       370       380         
pF1KSD YLKISPHGLEARCDASSFESVRCTFCVDAGVWYYEVTVVTSGVMQIGWATRDSKFLNHEG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 YLKISPHGLEARCDASSFESVRCTFCVDAGVWYYEVTVVTSGVMQIGWATRDSKFLNHEG
              370       380       390       400       410       420

     390       400       410       420       430       440         
pF1KSD YGIGDDEYSCAYDGCRQLIWYNARSKPHIHPCWKEGDTVGFLLDLNEKQMIFFLNGNQLP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 YGIGDDEYSCAYDGCRQLIWYNARSKPHIHPCWKEGDTVGFLLDLNEKQMIFFLNGNQLP
              430       440       450       460       470       480

     450       460       470       480       490       500         
pF1KSD PEKQVFSSTVSGFFAAASFMSYQQCEFNFGAKPFKYPPSMKFSTFNDYAFLTAEEKIILP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PEKQVFSSTVSGFFAAASFMSYQQCEFNFGAKPFKYPPSMKFSTFNDYAFLTAEEKIILP
              490       500       510       520       530       540

     510       520       530       540       550       560         
pF1KSD RHRRLALLKQVSIRENCCSLCCDEVADTQLKPCGHSDLCMDCALQLETCPLCRKEIVSRI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RHRRLALLKQVSIRENCCSLCCDEVADTQLKPCGHSDLCMDCALQLETCPLCRKEIVSRI
              550       560       570       580       590       600

     570      
pF1KSD RQISHIS
       :::::::
XP_011 RQISHIS
              

>>XP_016879333 (OMIM: 616585,616723) PREDICTED: RING fin  (452 aa)
 initn: 3080 init1: 3080 opt: 3080  Z-score: 2821.0  bits: 531.5 E(85289): 2.2e-150
Smith-Waterman score: 3080; 100.0% identity (100.0% similar) in 452 aa overlap (125-576:1-452)

          100       110       120       130       140       150    
pF1KSD RKKQNVDGLVLDTLAVIRTLVDNDQEPPYSMITLHEMAETDEGWLDVVQSLIRVIPLEDP
                                     ::::::::::::::::::::::::::::::
XP_016                               MITLHEMAETDEGWLDVVQSLIRVIPLEDP
                                             10        20        30

          160       170       180       190       200       210    
pF1KSD LGPAVITLLLDECPLPTKDALQKLTEILNLNGEVACQDSSHPAKHRNTSAVLGCLAEKLA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LGPAVITLLLDECPLPTKDALQKLTEILNLNGEVACQDSSHPAKHRNTSAVLGCLAEKLA
               40        50        60        70        80        90

          220       230       240       250       260       270    
pF1KSD GPASIGLLSPGILEYLLQCLKLQSHPTVMLFALIALEKFAQTSENKLTISESSISDRLVT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GPASIGLLSPGILEYLLQCLKLQSHPTVMLFALIALEKFAQTSENKLTISESSISDRLVT
              100       110       120       130       140       150

          280       290       300       310       320       330    
pF1KSD LESWANDPDYLKRQVGFCAQWSLDNLFLKEGRQLTYEKVNLSSIRAMLNSNDVSEYLKIS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LESWANDPDYLKRQVGFCAQWSLDNLFLKEGRQLTYEKVNLSSIRAMLNSNDVSEYLKIS
              160       170       180       190       200       210

          340       350       360       370       380       390    
pF1KSD PHGLEARCDASSFESVRCTFCVDAGVWYYEVTVVTSGVMQIGWATRDSKFLNHEGYGIGD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PHGLEARCDASSFESVRCTFCVDAGVWYYEVTVVTSGVMQIGWATRDSKFLNHEGYGIGD
              220       230       240       250       260       270

          400       410       420       430       440       450    
pF1KSD DEYSCAYDGCRQLIWYNARSKPHIHPCWKEGDTVGFLLDLNEKQMIFFLNGNQLPPEKQV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DEYSCAYDGCRQLIWYNARSKPHIHPCWKEGDTVGFLLDLNEKQMIFFLNGNQLPPEKQV
              280       290       300       310       320       330

          460       470       480       490       500       510    
pF1KSD FSSTVSGFFAAASFMSYQQCEFNFGAKPFKYPPSMKFSTFNDYAFLTAEEKIILPRHRRL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FSSTVSGFFAAASFMSYQQCEFNFGAKPFKYPPSMKFSTFNDYAFLTAEEKIILPRHRRL
              340       350       360       370       380       390

          520       530       540       550       560       570    
pF1KSD ALLKQVSIRENCCSLCCDEVADTQLKPCGHSDLCMDCALQLETCPLCRKEIVSRIRQISH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ALLKQVSIRENCCSLCCDEVADTQLKPCGHSDLCMDCALQLETCPLCRKEIVSRIRQISH
              400       410       420       430       440       450

         
pF1KSD IS
       ::
XP_016 IS
         

>>NP_001292111 (OMIM: 616585,616723) RING finger and SPR  (117 aa)
 initn: 780 init1: 780 opt: 780  Z-score: 729.5  bits: 142.6 E(85289): 6.8e-34
Smith-Waterman score: 780; 100.0% identity (100.0% similar) in 116 aa overlap (1-116:1-116)

               10        20        30        40        50        60
pF1KSD MIVFGWAVFLASRSLGQGLLLTLEEHIAHFLGTGGAATTMGNSCICRDDSGTDDSVDTQQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MIVFGWAVFLASRSLGQGLLLTLEEHIAHFLGTGGAATTMGNSCICRDDSGTDDSVDTQQ
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KSD QQAENSAVPTADTRSQPRDPVRPPRRGRGPHEPRRKKQNVDGLVLDTLAVIRTLVDNDQE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::    
NP_001 QQAENSAVPTADTRSQPRDPVRPPRRGRGPHEPRRKKQNVDGLVLDTLAVIRTLVDK   
               70        80        90       100       110          

              130       140       150       160       170       180
pF1KSD PPYSMITLHEMAETDEGWLDVVQSLIRVIPLEDPLGPAVITLLLDECPLPTKDALQKLTE

>>XP_016862507 (OMIM: 614472) PREDICTED: E3 ubiquitin-pr  (1314 aa)
 initn: 269 init1: 133 opt: 320  Z-score: 296.3  bits: 65.9 E(85289): 9.2e-10
Smith-Waterman score: 320; 37.8% identity (62.2% similar) in 143 aa overlap (345-486:119-257)

          320       330       340       350       360       370    
pF1KSD LSSIRAMLNSNDVSEYLKISPHGLEARCDASSFESVRCTFCVDAGVWYYEVTVVTSGVMQ
                                     :.: ..: : ::  : : ::: . ..:.::
XP_016 LGPSTVVLDHTGGFEGLLLVDDDLLGVIGHSNFGTIRSTTCVYKGKWLYEVLISSQGLMQ
       90       100       110       120       130       140        

          380       390       400       410       420       430    
pF1KSD IGWATRDSKFLNHEGYGIGDDEYSCAYDGCRQLIWYNARSKPHIHPCWKEGDTVGFLLDL
       ::: : . .: ..:  :.:: . : :::: :   : :. .  .    :  :: :. :.::
XP_016 IGWCTISCRFNQEE--GVGDTHNSYAYDGNRVRKW-NVTTTNY-GKAWAAGDIVSCLIDL
      150       160         170       180         190       200    

          440       450       460        470       480       490   
pF1KSD NEKQMIFFLNGNQLPPEKQVFSSTVS-GFFAAASFMSYQQCEFNFGAKPFKYPPSMKFST
       ..  . : ::: .:    . .:  .. ..: : :.   ..  ::::..:..::       
XP_016 DDGTLSFCLNGVSLGTAFENLSRGLGMAYFPAISLSFKESVAFNFGSRPLRYPVAGYRPL
          210       220       230       240       250       260    

           500       510       520       530       540       550   
pF1KSD FNDYAFLTAEEKIILPRHRRLALLKQVSIRENCCSLCCDEVADTQLKPCGHSDLCMDCAL
                                                                   
XP_016 QDPPSADLVRAQRLLGCFRAVLSVELDPVEGRLLDKESSKWRLRGQPTVLLTLAHIFHHF
          270       280       290       300       310       320    




576 residues in 1 query   sequences
60827320 residues in 85289 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Thu Nov  3 07:54:32 2016 done: Thu Nov  3 07:54:33 2016
 Total Scan time: 10.060 Total Display time:  0.100

Function used was FASTA [36.3.4 Apr, 2011]
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