Result of FASTA (omim) for pF1KSDA1960
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KSDA1960, 852 aa
  1>>>pF1KSDA1960 852 - 852 aa - 852 aa
Library: /omim/omim.rfq.tfa
  60827320 residues in 85289 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 9.7683+/-0.000339; mu= 2.2178+/- 0.021
 mean_var=274.8605+/-56.895, 0's: 0 Z-trim(124.0): 55  B-trim: 1009 in 2/58
 Lambda= 0.077360
 statistics sampled from 44681 (44751) to 44681 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.805), E-opt: 0.2 (0.525), width:  16
 Scan time: 15.800

The best scores are:                                      opt bits E(85289)
NP_001166171 (OMIM: 611179) protein Shroom1 isofor ( 852) 5833 664.6 5.2e-190
XP_005271942 (OMIM: 611179) PREDICTED: protein Shr ( 852) 5833 664.6 5.2e-190
XP_005271943 (OMIM: 611179) PREDICTED: protein Shr ( 852) 5833 664.6 5.2e-190
XP_011541469 (OMIM: 611179) PREDICTED: protein Shr ( 852) 5833 664.6 5.2e-190
NP_597713 (OMIM: 611179) protein Shroom1 isoform 2 ( 847) 5786 659.4  2e-188
XP_006714597 (OMIM: 611179) PREDICTED: protein Shr ( 490) 3217 372.5 2.7e-102
XP_005263222 (OMIM: 604570) PREDICTED: protein Shr (1820)  422 61.0 5.8e-08
XP_011530463 (OMIM: 604570) PREDICTED: protein Shr (1820)  422 61.0 5.8e-08
XP_005263221 (OMIM: 604570) PREDICTED: protein Shr (1820)  422 61.0 5.8e-08
XP_005263220 (OMIM: 604570) PREDICTED: protein Shr (1820)  422 61.0 5.8e-08
XP_011530462 (OMIM: 604570) PREDICTED: protein Shr (1871)  422 61.0 5.9e-08
XP_006714345 (OMIM: 604570) PREDICTED: protein Shr (1961)  422 61.0 6.1e-08
XP_016863978 (OMIM: 604570) PREDICTED: protein Shr (1961)  422 61.0 6.1e-08
XP_016863977 (OMIM: 604570) PREDICTED: protein Shr (1962)  422 61.0 6.1e-08
NP_065910 (OMIM: 604570) protein Shroom3 [Homo sap (1996)  422 61.0 6.2e-08
XP_011530460 (OMIM: 604570) PREDICTED: protein Shr (1997)  422 61.0 6.2e-08
XP_011530461 (OMIM: 604570) PREDICTED: protein Shr (1997)  422 61.0 6.2e-08
XP_011530459 (OMIM: 604570) PREDICTED: protein Shr (2002)  422 61.0 6.2e-08
XP_011543808 (OMIM: 300103) PREDICTED: protein Shr ( 451)  400 58.0 1.1e-07
NP_001307592 (OMIM: 300103) protein Shroom2 isofor ( 451)  400 58.0 1.1e-07
XP_016884982 (OMIM: 300103) PREDICTED: protein Shr ( 451)  400 58.0 1.1e-07
XP_016884981 (OMIM: 300103) PREDICTED: protein Shr ( 450)  391 57.0 2.2e-07
XP_016884983 (OMIM: 300103) PREDICTED: protein Shr ( 450)  391 57.0 2.2e-07
NP_001307593 (OMIM: 300103) protein Shroom2 isofor ( 450)  391 57.0 2.2e-07
NP_001640 (OMIM: 300103) protein Shroom2 isoform 1 (1616)  400 58.5 2.9e-07
XP_005274557 (OMIM: 300103) PREDICTED: protein Shr (1615)  391 57.5 5.8e-07
XP_016885175 (OMIM: 300434,300579) PREDICTED: prot (1373)  367 54.8 3.3e-06
XP_016885173 (OMIM: 300434,300579) PREDICTED: prot (1415)  367 54.8 3.4e-06
XP_016885172 (OMIM: 300434,300579) PREDICTED: prot (1486)  367 54.8 3.5e-06
NP_065768 (OMIM: 300434,300579) protein Shroom4 [H (1493)  367 54.8 3.5e-06
XP_016885171 (OMIM: 300434,300579) PREDICTED: prot (1531)  367 54.8 3.6e-06


>>NP_001166171 (OMIM: 611179) protein Shroom1 isoform 1   (852 aa)
 initn: 5833 init1: 5833 opt: 5833  Z-score: 3532.3  bits: 664.6 E(85289): 5.2e-190
Smith-Waterman score: 5833; 100.0% identity (100.0% similar) in 852 aa overlap (1-852:1-852)

               10        20        30        40        50        60
pF1KSD MEALGPGGDRASPASSTSSLDLWHLSMRADSAYSSFSAASGGPEPRTQSPGTDLLPYLDW
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MEALGPGGDRASPASSTSSLDLWHLSMRADSAYSSFSAASGGPEPRTQSPGTDLLPYLDW
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KSD DYVRVVWGGPGPAPPDAALCTSPRPRPAVAARSGPQPTEVPGTPGPLNRQATPLLYALAA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DYVRVVWGGPGPAPPDAALCTSPRPRPAVAARSGPQPTEVPGTPGPLNRQATPLLYALAA
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KSD EAEAAAQAAEPPSPPASRAAYRQRLQGAQRRVLRETSFQRKELRMSLPARLRPTVPARPP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EAEAAAQAAEPPSPPASRAAYRQRLQGAQRRVLRETSFQRKELRMSLPARLRPTVPARPP
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KSD ATHPRSASLSHPGGEGEPARSRAPAPGTAGRGPLANQQRKWCFSEPGKLDRVGRGGGPAR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ATHPRSASLSHPGGEGEPARSRAPAPGTAGRGPLANQQRKWCFSEPGKLDRVGRGGGPAR
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KSD ECLGEACSSSGLPGPEPLEFQHPALAKFEDHEVGWLPETQPQGSMNLDSGSLKLGDAFRP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ECLGEACSSSGLPGPEPLEFQHPALAKFEDHEVGWLPETQPQGSMNLDSGSLKLGDAFRP
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KSD ASRSRSASGEVLGSWGGSGGTIPIVQAVPQGAETPRPLFQTKLSRFLPQKEAAVMYPAEL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ASRSRSASGEVLGSWGGSGGTIPIVQAVPQGAETPRPLFQTKLSRFLPQKEAAVMYPAEL
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KSD PQSSPADSEQRVSETCIVPAWLPSLPDEVFLEEAPLVRMRSPPDPHASQGPPASVHASDQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PQSSPADSEQRVSETCIVPAWLPSLPDEVFLEEAPLVRMRSPPDPHASQGPPASVHASDQ
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KSD PYGTGLGQRTGQVTVPTEYPLHECPGTAGADDCWQGVNGSVGISRPTSHTPTGTANDNIP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PYGTGLGQRTGQVTVPTEYPLHECPGTAGADDCWQGVNGSVGISRPTSHTPTGTANDNIP
              430       440       450       460       470       480

              490       500       510       520       530       540
pF1KSD TIDPTGLTTNPPTAAESDLLKPVPADALGLSGNDTPGPSHNTALARGTGQPGSRPTWPSQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TIDPTGLTTNPPTAAESDLLKPVPADALGLSGNDTPGPSHNTALARGTGQPGSRPTWPSQ
              490       500       510       520       530       540

              550       560       570       580       590       600
pF1KSD CLEELVQELARLDPSLCDPLASQPSPEPPLGLLDGLIPLAEVRAAMRPACGEAGEEAAST
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 CLEELVQELARLDPSLCDPLASQPSPEPPLGLLDGLIPLAEVRAAMRPACGEAGEEAAST
              550       560       570       580       590       600

              610       620       630       640       650       660
pF1KSD FEPGSYQFSFTQLLPAPREETRLENPATHPVLDQPCGQGLPAPNNSIQGKKVELAARLQK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FEPGSYQFSFTQLLPAPREETRLENPATHPVLDQPCGQGLPAPNNSIQGKKVELAARLQK
              610       620       630       640       650       660

              670       680       690       700       710       720
pF1KSD MLQDLHTEQERLQGEAQAWARRQAALEAAVRQACAPQELERFSRFMADLERVLGLLLLLG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MLQDLHTEQERLQGEAQAWARRQAALEAAVRQACAPQELERFSRFMADLERVLGLLLLLG
              670       680       690       700       710       720

              730       740       750       760       770       780
pF1KSD SRLARVRRALARAASDSDPDEQASLLQRLRLLQRQEEDAKELKEHVARRERAVREVLVRA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SRLARVRRALARAASDSDPDEQASLLQRLRLLQRQEEDAKELKEHVARRERAVREVLVRA
              730       740       750       760       770       780

              790       800       810       820       830       840
pF1KSD LPVEELRVYCALLAGKAAVLAQQRNLDERIRLLQDQLDAIRDDLGHHAPSPSPARPPGTC
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LPVEELRVYCALLAGKAAVLAQQRNLDERIRLLQDQLDAIRDDLGHHAPSPSPARPPGTC
              790       800       810       820       830       840

              850  
pF1KSD PPVQPPFPLLLT
       ::::::::::::
NP_001 PPVQPPFPLLLT
              850  

>>XP_005271942 (OMIM: 611179) PREDICTED: protein Shroom1  (852 aa)
 initn: 5833 init1: 5833 opt: 5833  Z-score: 3532.3  bits: 664.6 E(85289): 5.2e-190
Smith-Waterman score: 5833; 100.0% identity (100.0% similar) in 852 aa overlap (1-852:1-852)

               10        20        30        40        50        60
pF1KSD MEALGPGGDRASPASSTSSLDLWHLSMRADSAYSSFSAASGGPEPRTQSPGTDLLPYLDW
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MEALGPGGDRASPASSTSSLDLWHLSMRADSAYSSFSAASGGPEPRTQSPGTDLLPYLDW
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KSD DYVRVVWGGPGPAPPDAALCTSPRPRPAVAARSGPQPTEVPGTPGPLNRQATPLLYALAA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 DYVRVVWGGPGPAPPDAALCTSPRPRPAVAARSGPQPTEVPGTPGPLNRQATPLLYALAA
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KSD EAEAAAQAAEPPSPPASRAAYRQRLQGAQRRVLRETSFQRKELRMSLPARLRPTVPARPP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 EAEAAAQAAEPPSPPASRAAYRQRLQGAQRRVLRETSFQRKELRMSLPARLRPTVPARPP
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KSD ATHPRSASLSHPGGEGEPARSRAPAPGTAGRGPLANQQRKWCFSEPGKLDRVGRGGGPAR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 ATHPRSASLSHPGGEGEPARSRAPAPGTAGRGPLANQQRKWCFSEPGKLDRVGRGGGPAR
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KSD ECLGEACSSSGLPGPEPLEFQHPALAKFEDHEVGWLPETQPQGSMNLDSGSLKLGDAFRP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 ECLGEACSSSGLPGPEPLEFQHPALAKFEDHEVGWLPETQPQGSMNLDSGSLKLGDAFRP
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KSD ASRSRSASGEVLGSWGGSGGTIPIVQAVPQGAETPRPLFQTKLSRFLPQKEAAVMYPAEL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 ASRSRSASGEVLGSWGGSGGTIPIVQAVPQGAETPRPLFQTKLSRFLPQKEAAVMYPAEL
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KSD PQSSPADSEQRVSETCIVPAWLPSLPDEVFLEEAPLVRMRSPPDPHASQGPPASVHASDQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 PQSSPADSEQRVSETCIVPAWLPSLPDEVFLEEAPLVRMRSPPDPHASQGPPASVHASDQ
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KSD PYGTGLGQRTGQVTVPTEYPLHECPGTAGADDCWQGVNGSVGISRPTSHTPTGTANDNIP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 PYGTGLGQRTGQVTVPTEYPLHECPGTAGADDCWQGVNGSVGISRPTSHTPTGTANDNIP
              430       440       450       460       470       480

              490       500       510       520       530       540
pF1KSD TIDPTGLTTNPPTAAESDLLKPVPADALGLSGNDTPGPSHNTALARGTGQPGSRPTWPSQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 TIDPTGLTTNPPTAAESDLLKPVPADALGLSGNDTPGPSHNTALARGTGQPGSRPTWPSQ
              490       500       510       520       530       540

              550       560       570       580       590       600
pF1KSD CLEELVQELARLDPSLCDPLASQPSPEPPLGLLDGLIPLAEVRAAMRPACGEAGEEAAST
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 CLEELVQELARLDPSLCDPLASQPSPEPPLGLLDGLIPLAEVRAAMRPACGEAGEEAAST
              550       560       570       580       590       600

              610       620       630       640       650       660
pF1KSD FEPGSYQFSFTQLLPAPREETRLENPATHPVLDQPCGQGLPAPNNSIQGKKVELAARLQK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 FEPGSYQFSFTQLLPAPREETRLENPATHPVLDQPCGQGLPAPNNSIQGKKVELAARLQK
              610       620       630       640       650       660

              670       680       690       700       710       720
pF1KSD MLQDLHTEQERLQGEAQAWARRQAALEAAVRQACAPQELERFSRFMADLERVLGLLLLLG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MLQDLHTEQERLQGEAQAWARRQAALEAAVRQACAPQELERFSRFMADLERVLGLLLLLG
              670       680       690       700       710       720

              730       740       750       760       770       780
pF1KSD SRLARVRRALARAASDSDPDEQASLLQRLRLLQRQEEDAKELKEHVARRERAVREVLVRA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SRLARVRRALARAASDSDPDEQASLLQRLRLLQRQEEDAKELKEHVARRERAVREVLVRA
              730       740       750       760       770       780

              790       800       810       820       830       840
pF1KSD LPVEELRVYCALLAGKAAVLAQQRNLDERIRLLQDQLDAIRDDLGHHAPSPSPARPPGTC
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LPVEELRVYCALLAGKAAVLAQQRNLDERIRLLQDQLDAIRDDLGHHAPSPSPARPPGTC
              790       800       810       820       830       840

              850  
pF1KSD PPVQPPFPLLLT
       ::::::::::::
XP_005 PPVQPPFPLLLT
              850  

>>XP_005271943 (OMIM: 611179) PREDICTED: protein Shroom1  (852 aa)
 initn: 5833 init1: 5833 opt: 5833  Z-score: 3532.3  bits: 664.6 E(85289): 5.2e-190
Smith-Waterman score: 5833; 100.0% identity (100.0% similar) in 852 aa overlap (1-852:1-852)

               10        20        30        40        50        60
pF1KSD MEALGPGGDRASPASSTSSLDLWHLSMRADSAYSSFSAASGGPEPRTQSPGTDLLPYLDW
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MEALGPGGDRASPASSTSSLDLWHLSMRADSAYSSFSAASGGPEPRTQSPGTDLLPYLDW
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KSD DYVRVVWGGPGPAPPDAALCTSPRPRPAVAARSGPQPTEVPGTPGPLNRQATPLLYALAA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 DYVRVVWGGPGPAPPDAALCTSPRPRPAVAARSGPQPTEVPGTPGPLNRQATPLLYALAA
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KSD EAEAAAQAAEPPSPPASRAAYRQRLQGAQRRVLRETSFQRKELRMSLPARLRPTVPARPP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 EAEAAAQAAEPPSPPASRAAYRQRLQGAQRRVLRETSFQRKELRMSLPARLRPTVPARPP
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KSD ATHPRSASLSHPGGEGEPARSRAPAPGTAGRGPLANQQRKWCFSEPGKLDRVGRGGGPAR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 ATHPRSASLSHPGGEGEPARSRAPAPGTAGRGPLANQQRKWCFSEPGKLDRVGRGGGPAR
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KSD ECLGEACSSSGLPGPEPLEFQHPALAKFEDHEVGWLPETQPQGSMNLDSGSLKLGDAFRP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 ECLGEACSSSGLPGPEPLEFQHPALAKFEDHEVGWLPETQPQGSMNLDSGSLKLGDAFRP
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KSD ASRSRSASGEVLGSWGGSGGTIPIVQAVPQGAETPRPLFQTKLSRFLPQKEAAVMYPAEL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 ASRSRSASGEVLGSWGGSGGTIPIVQAVPQGAETPRPLFQTKLSRFLPQKEAAVMYPAEL
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KSD PQSSPADSEQRVSETCIVPAWLPSLPDEVFLEEAPLVRMRSPPDPHASQGPPASVHASDQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 PQSSPADSEQRVSETCIVPAWLPSLPDEVFLEEAPLVRMRSPPDPHASQGPPASVHASDQ
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KSD PYGTGLGQRTGQVTVPTEYPLHECPGTAGADDCWQGVNGSVGISRPTSHTPTGTANDNIP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 PYGTGLGQRTGQVTVPTEYPLHECPGTAGADDCWQGVNGSVGISRPTSHTPTGTANDNIP
              430       440       450       460       470       480

              490       500       510       520       530       540
pF1KSD TIDPTGLTTNPPTAAESDLLKPVPADALGLSGNDTPGPSHNTALARGTGQPGSRPTWPSQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 TIDPTGLTTNPPTAAESDLLKPVPADALGLSGNDTPGPSHNTALARGTGQPGSRPTWPSQ
              490       500       510       520       530       540

              550       560       570       580       590       600
pF1KSD CLEELVQELARLDPSLCDPLASQPSPEPPLGLLDGLIPLAEVRAAMRPACGEAGEEAAST
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 CLEELVQELARLDPSLCDPLASQPSPEPPLGLLDGLIPLAEVRAAMRPACGEAGEEAAST
              550       560       570       580       590       600

              610       620       630       640       650       660
pF1KSD FEPGSYQFSFTQLLPAPREETRLENPATHPVLDQPCGQGLPAPNNSIQGKKVELAARLQK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 FEPGSYQFSFTQLLPAPREETRLENPATHPVLDQPCGQGLPAPNNSIQGKKVELAARLQK
              610       620       630       640       650       660

              670       680       690       700       710       720
pF1KSD MLQDLHTEQERLQGEAQAWARRQAALEAAVRQACAPQELERFSRFMADLERVLGLLLLLG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MLQDLHTEQERLQGEAQAWARRQAALEAAVRQACAPQELERFSRFMADLERVLGLLLLLG
              670       680       690       700       710       720

              730       740       750       760       770       780
pF1KSD SRLARVRRALARAASDSDPDEQASLLQRLRLLQRQEEDAKELKEHVARRERAVREVLVRA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SRLARVRRALARAASDSDPDEQASLLQRLRLLQRQEEDAKELKEHVARRERAVREVLVRA
              730       740       750       760       770       780

              790       800       810       820       830       840
pF1KSD LPVEELRVYCALLAGKAAVLAQQRNLDERIRLLQDQLDAIRDDLGHHAPSPSPARPPGTC
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LPVEELRVYCALLAGKAAVLAQQRNLDERIRLLQDQLDAIRDDLGHHAPSPSPARPPGTC
              790       800       810       820       830       840

              850  
pF1KSD PPVQPPFPLLLT
       ::::::::::::
XP_005 PPVQPPFPLLLT
              850  

>>XP_011541469 (OMIM: 611179) PREDICTED: protein Shroom1  (852 aa)
 initn: 5833 init1: 5833 opt: 5833  Z-score: 3532.3  bits: 664.6 E(85289): 5.2e-190
Smith-Waterman score: 5833; 100.0% identity (100.0% similar) in 852 aa overlap (1-852:1-852)

               10        20        30        40        50        60
pF1KSD MEALGPGGDRASPASSTSSLDLWHLSMRADSAYSSFSAASGGPEPRTQSPGTDLLPYLDW
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MEALGPGGDRASPASSTSSLDLWHLSMRADSAYSSFSAASGGPEPRTQSPGTDLLPYLDW
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KSD DYVRVVWGGPGPAPPDAALCTSPRPRPAVAARSGPQPTEVPGTPGPLNRQATPLLYALAA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DYVRVVWGGPGPAPPDAALCTSPRPRPAVAARSGPQPTEVPGTPGPLNRQATPLLYALAA
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KSD EAEAAAQAAEPPSPPASRAAYRQRLQGAQRRVLRETSFQRKELRMSLPARLRPTVPARPP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EAEAAAQAAEPPSPPASRAAYRQRLQGAQRRVLRETSFQRKELRMSLPARLRPTVPARPP
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KSD ATHPRSASLSHPGGEGEPARSRAPAPGTAGRGPLANQQRKWCFSEPGKLDRVGRGGGPAR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ATHPRSASLSHPGGEGEPARSRAPAPGTAGRGPLANQQRKWCFSEPGKLDRVGRGGGPAR
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KSD ECLGEACSSSGLPGPEPLEFQHPALAKFEDHEVGWLPETQPQGSMNLDSGSLKLGDAFRP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ECLGEACSSSGLPGPEPLEFQHPALAKFEDHEVGWLPETQPQGSMNLDSGSLKLGDAFRP
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KSD ASRSRSASGEVLGSWGGSGGTIPIVQAVPQGAETPRPLFQTKLSRFLPQKEAAVMYPAEL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ASRSRSASGEVLGSWGGSGGTIPIVQAVPQGAETPRPLFQTKLSRFLPQKEAAVMYPAEL
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KSD PQSSPADSEQRVSETCIVPAWLPSLPDEVFLEEAPLVRMRSPPDPHASQGPPASVHASDQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PQSSPADSEQRVSETCIVPAWLPSLPDEVFLEEAPLVRMRSPPDPHASQGPPASVHASDQ
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KSD PYGTGLGQRTGQVTVPTEYPLHECPGTAGADDCWQGVNGSVGISRPTSHTPTGTANDNIP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PYGTGLGQRTGQVTVPTEYPLHECPGTAGADDCWQGVNGSVGISRPTSHTPTGTANDNIP
              430       440       450       460       470       480

              490       500       510       520       530       540
pF1KSD TIDPTGLTTNPPTAAESDLLKPVPADALGLSGNDTPGPSHNTALARGTGQPGSRPTWPSQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TIDPTGLTTNPPTAAESDLLKPVPADALGLSGNDTPGPSHNTALARGTGQPGSRPTWPSQ
              490       500       510       520       530       540

              550       560       570       580       590       600
pF1KSD CLEELVQELARLDPSLCDPLASQPSPEPPLGLLDGLIPLAEVRAAMRPACGEAGEEAAST
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 CLEELVQELARLDPSLCDPLASQPSPEPPLGLLDGLIPLAEVRAAMRPACGEAGEEAAST
              550       560       570       580       590       600

              610       620       630       640       650       660
pF1KSD FEPGSYQFSFTQLLPAPREETRLENPATHPVLDQPCGQGLPAPNNSIQGKKVELAARLQK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FEPGSYQFSFTQLLPAPREETRLENPATHPVLDQPCGQGLPAPNNSIQGKKVELAARLQK
              610       620       630       640       650       660

              670       680       690       700       710       720
pF1KSD MLQDLHTEQERLQGEAQAWARRQAALEAAVRQACAPQELERFSRFMADLERVLGLLLLLG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MLQDLHTEQERLQGEAQAWARRQAALEAAVRQACAPQELERFSRFMADLERVLGLLLLLG
              670       680       690       700       710       720

              730       740       750       760       770       780
pF1KSD SRLARVRRALARAASDSDPDEQASLLQRLRLLQRQEEDAKELKEHVARRERAVREVLVRA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SRLARVRRALARAASDSDPDEQASLLQRLRLLQRQEEDAKELKEHVARRERAVREVLVRA
              730       740       750       760       770       780

              790       800       810       820       830       840
pF1KSD LPVEELRVYCALLAGKAAVLAQQRNLDERIRLLQDQLDAIRDDLGHHAPSPSPARPPGTC
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LPVEELRVYCALLAGKAAVLAQQRNLDERIRLLQDQLDAIRDDLGHHAPSPSPARPPGTC
              790       800       810       820       830       840

              850  
pF1KSD PPVQPPFPLLLT
       ::::::::::::
XP_011 PPVQPPFPLLLT
              850  

>>NP_597713 (OMIM: 611179) protein Shroom1 isoform 2 [Ho  (847 aa)
 initn: 5119 init1: 5119 opt: 5786  Z-score: 3503.9  bits: 659.4 E(85289): 2e-188
Smith-Waterman score: 5786; 99.4% identity (99.4% similar) in 852 aa overlap (1-852:1-847)

               10        20        30        40        50        60
pF1KSD MEALGPGGDRASPASSTSSLDLWHLSMRADSAYSSFSAASGGPEPRTQSPGTDLLPYLDW
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_597 MEALGPGGDRASPASSTSSLDLWHLSMRADSAYSSFSAASGGPEPRTQSPGTDLLPYLDW
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KSD DYVRVVWGGPGPAPPDAALCTSPRPRPAVAARSGPQPTEVPGTPGPLNRQATPLLYALAA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_597 DYVRVVWGGPGPAPPDAALCTSPRPRPAVAARSGPQPTEVPGTPGPLNRQATPLLYALAA
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KSD EAEAAAQAAEPPSPPASRAAYRQRLQGAQRRVLRETSFQRKELRMSLPARLRPTVPARPP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_597 EAEAAAQAAEPPSPPASRAAYRQRLQGAQRRVLRETSFQRKELRMSLPARLRPTVPARPP
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KSD ATHPRSASLSHPGGEGEPARSRAPAPGTAGRGPLANQQRKWCFSEPGKLDRVGRGGGPAR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_597 ATHPRSASLSHPGGEGEPARSRAPAPGTAGRGPLANQQRKWCFSEPGKLDRVGRGGGPAR
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KSD ECLGEACSSSGLPGPEPLEFQHPALAKFEDHEVGWLPETQPQGSMNLDSGSLKLGDAFRP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_597 ECLGEACSSSGLPGPEPLEFQHPALAKFEDHEVGWLPETQPQGSMNLDSGSLKLGDAFRP
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KSD ASRSRSASGEVLGSWGGSGGTIPIVQAVPQGAETPRPLFQTKLSRFLPQKEAAVMYPAEL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_597 ASRSRSASGEVLGSWGGSGGTIPIVQAVPQGAETPRPLFQTKLSRFLPQKEAAVMYPAEL
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KSD PQSSPADSEQRVSETCIVPAWLPSLPDEVFLEEAPLVRMRSPPDPHASQGPPASVHASDQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_597 PQSSPADSEQRVSETCIVPAWLPSLPDEVFLEEAPLVRMRSPPDPHASQGPPASVHASDQ
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KSD PYGTGLGQRTGQVTVPTEYPLHECPGTAGADDCWQGVNGSVGISRPTSHTPTGTANDNIP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_597 PYGTGLGQRTGQVTVPTEYPLHECPGTAGADDCWQGVNGSVGISRPTSHTPTGTANDNIP
              430       440       450       460       470       480

              490       500       510       520       530       540
pF1KSD TIDPTGLTTNPPTAAESDLLKPVPADALGLSGNDTPGPSHNTALARGTGQPGSRPTWPSQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_597 TIDPTGLTTNPPTAAESDLLKPVPADALGLSGNDTPGPSHNTALARGTGQPGSRPTWPSQ
              490       500       510       520       530       540

              550       560       570       580       590       600
pF1KSD CLEELVQELARLDPSLCDPLASQPSPEPPLGLLDGLIPLAEVRAAMRPACGEAGEEAAST
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_597 CLEELVQELARLDPSLCDPLASQPSPEPPLGLLDGLIPLAEVRAAMRPACGEAGEEAAST
              550       560       570       580       590       600

              610       620       630       640       650       660
pF1KSD FEPGSYQFSFTQLLPAPREETRLENPATHPVLDQPCGQGLPAPNNSIQGKKVELAARLQK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_597 FEPGSYQFSFTQLLPAPREETRLENPATHPVLDQPCGQGLPAPNNSIQGKKVELAARLQK
              610       620       630       640       650       660

              670       680       690       700       710       720
pF1KSD MLQDLHTEQERLQGEAQAWARRQAALEAAVRQACAPQELERFSRFMADLERVLGLLLLLG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_597 MLQDLHTEQERLQGEAQAWARRQAALEAAVRQACAPQELERFSRFMADLERVLGLLLLLG
              670       680       690       700       710       720

              730       740       750       760       770       780
pF1KSD SRLARVRRALARAASDSDPDEQASLLQRLRLLQRQEEDAKELKEHVARRERAVREVLVRA
       ::::::::::::::::::::::     :::::::::::::::::::::::::::::::::
NP_597 SRLARVRRALARAASDSDPDEQ-----RLRLLQRQEEDAKELKEHVARRERAVREVLVRA
              730       740            750       760       770     

              790       800       810       820       830       840
pF1KSD LPVEELRVYCALLAGKAAVLAQQRNLDERIRLLQDQLDAIRDDLGHHAPSPSPARPPGTC
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_597 LPVEELRVYCALLAGKAAVLAQQRNLDERIRLLQDQLDAIRDDLGHHAPSPSPARPPGTC
         780       790       800       810       820       830     

              850  
pF1KSD PPVQPPFPLLLT
       ::::::::::::
NP_597 PPVQPPFPLLLT
         840       

>>XP_006714597 (OMIM: 611179) PREDICTED: protein Shroom1  (490 aa)
 initn: 3254 init1: 3216 opt: 3217  Z-score: 1957.6  bits: 372.5 E(85289): 2.7e-102
Smith-Waterman score: 3217; 98.9% identity (99.4% similar) in 468 aa overlap (1-468:1-466)

               10        20        30        40        50        60
pF1KSD MEALGPGGDRASPASSTSSLDLWHLSMRADSAYSSFSAASGGPEPRTQSPGTDLLPYLDW
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 MEALGPGGDRASPASSTSSLDLWHLSMRADSAYSSFSAASGGPEPRTQSPGTDLLPYLDW
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KSD DYVRVVWGGPGPAPPDAALCTSPRPRPAVAARSGPQPTEVPGTPGPLNRQATPLLYALAA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 DYVRVVWGGPGPAPPDAALCTSPRPRPAVAARSGPQPTEVPGTPGPLNRQATPLLYALAA
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KSD EAEAAAQAAEPPSPPASRAAYRQRLQGAQRRVLRETSFQRKELRMSLPARLRPTVPARPP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 EAEAAAQAAEPPSPPASRAAYRQRLQGAQRRVLRETSFQRKELRMSLPARLRPTVPARPP
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KSD ATHPRSASLSHPGGEGEPARSRAPAPGTAGRGPLANQQRKWCFSEPGKLDRVGRGGGPAR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 ATHPRSASLSHPGGEGEPARSRAPAPGTAGRGPLANQQRKWCFSEPGKLDRVGRGGGPAR
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KSD ECLGEACSSSGLPGPEPLEFQHPALAKFEDHEVGWLPETQPQGSMNLDSGSLKLGDAFRP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 ECLGEACSSSGLPGPEPLEFQHPALAKFEDHEVGWLPETQPQGSMNLDSGSLKLGDAFRP
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KSD ASRSRSASGEVLGSWGGSGGTIPIVQAVPQGAETPRPLFQTKLSRFLPQKEAAVMYPAEL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 ASRSRSASGEVLGSWGGSGGTIPIVQAVPQGAETPRPLFQTKLSRFLPQKEAAVMYPAEL
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KSD PQSSPADSEQRVSETCIVPAWLPSLPDEVFLEEAPLVRMRSPPDPHASQGPPASVHASDQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 PQSSPADSEQRVSETCIVPAWLPSLPDEVFLEEAPLVRMRSPPDPHASQGPPASVHASDQ
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KSD PYGTGLGQRTGQVTVPTEYPLHECPGTAGADDCWQGVNGSVGISRPTSHTPTGTANDNIP
       ::::::::::::::::::::::::::::::::::::::::  ..: ::            
XP_006 PYGTGLGQRTGQVTVPTEYPLHECPGTAGADDCWQGVNGS--LQRVTSSNLSQLMPWDFQ
              430       440       450       460         470        

              490       500       510       520       530       540
pF1KSD TIDPTGLTTNPPTAAESDLLKPVPADALGLSGNDTPGPSHNTALARGTGQPGSRPTWPSQ
                                                                   
XP_006 AMILQVPLTILP                                                
      480       490                                                

>>XP_005263222 (OMIM: 604570) PREDICTED: protein Shroom3  (1820 aa)
 initn: 621 init1: 352 opt: 422  Z-score: 264.0  bits: 61.0 E(85289): 5.8e-08
Smith-Waterman score: 494; 23.1% identity (50.1% similar) in 888 aa overlap (5-843:948-1802)

                                            10        20        30 
pF1KSD                           MEALGPG---GDRASPASSTSSLDLWHLSMRADS
                                     ::.   :.  . ::: :::    :. : ..
XP_005 TGKRPTSAAGCSLQEPGPLRERAQSAYLQPGPAALEGSGLASASSLSSLREPSLQPRREA
       920       930       940       950       960       970       

              40        50            60        70             80  
pF1KSD AYSSFSAASGGPEPRTQSP----GTDLLPYLDWDYVRVVWGGP-----GPAPPDAALCTS
       .    ..:     :: .:     :  :      : .  . ::      :   :      .
XP_005 TLLPATVAETQQAPRDRSSSFAGGRRLGERRRGDLLSGANGGTRGTQRGDETPREPSSWG
       980       990      1000      1010      1020      1030       

             90       100       110       120       130       140  
pF1KSD PRPRPAVAARSGPQPTEVPGTPGPLNRQATPLLYALAAEAEAAAQAAEPPSPPASRAAYR
        :   ...:..  . ..: . :  .  ...:   : : . . .  . .     ..   : 
XP_005 ARAGKSMSAEDLLERSDVLAGPVHVRSRSSP---ATADKRQDVLLGQDSGFGLVKDPCY-
      1040      1050      1060         1070      1080      1090    

            150       160       170        180       190        200
pF1KSD QRLQGAQRRVLRETSFQRKELRMSLPARLRPTVPARP-PATHPRSASLSHPGG-EGEPAR
         : :   : :  .   ..:. . :  .: :   .    :    :.    ::  . .   
XP_005 --LAGPGSRSLSCSERGQEEM-LPLFHHLTPRWGGSGCKAIGDSSVPSECPGTLDHQRQA
            1100      1110       1120      1130      1140      1150

              210       220       230       240        250         
pF1KSD SRAPAPGTAGRGPLANQQRKWCFSEPGKLDRVGRGGGPARECLGEA-CSSSGLPGPEPLE
       ::.: :    : :::. :     .. . :  .:    :    .  . ::..:  : .:: 
XP_005 SRTPCP----RPPLAGTQGLVTDTRAAPLTPIGT---PLPSAIPSGYCSQDGQTGRQPLP
                 1160      1170      1180         1190      1200   

     260       270       280       290       300       310         
pF1KSD FQHPALAKFEDHEVGWLPETQPQGSMNLDSGSLKLGDAFRPASRSRSASGE----VLGSW
          ::.     :. .    ::: :  . .. . . :   . ..:.: .  .      ..:
XP_005 PYTPAMM----HRSNGHTLTQPPGPRGCEGDGPEHG--VEEGTRKRVSLPQWPPPSRAKW
          1210          1220      1230        1240      1250       

           320       330       340       350       360       370   
pF1KSD GGSG--GTIPIVQAVPQGAETPRPLFQTKLSRFLPQKEAAVMYPAELPQSSPADSEQRVS
       . ..   ..:  ...:. :.  .   : .:  .   ..  .  :   : :.:.    :.:
XP_005 AHAAREDSLPEESSAPDFANLKHYQKQQSLPSLCSTSDPDT--PLGAP-STPGRISLRIS
      1260      1270      1280      1290        1300       1310    

           380         390               400       410       420   
pF1KSD ETCIVPAWLP--SLPDEVFLEE-------APLVR-MRSPPDPHASQGPPASVHASDQPYG
       :. .  .  :  .  ::::...       .:  . .  :: :  ::  :  :.. :. . 
XP_005 ESVLRDSPPPHEDYEDEVFVRDPHPKATSSPTFEPLPPPPPPPPSQETP--VYSMDD-FP
         1320      1330      1340      1350      1360         1370 

           430       440              450       460       470      
pF1KSD TGLGQRTGQVTVPTEYPLHECPG-------TAGADDCWQGVNGSVGISRPTSHTPTGTAN
           . . .. . .: :    :.       : . .    :.   :: .  .:.  :.  .
XP_005 PPPPHTVCEAQLDSEDPEGPRPSFNKLSKVTIARERHMPGAAHVVGSQTLASRLQTSIKG
            1380      1390      1400      1410      1420      1430 

        480       490       500       510       520       530      
pF1KSD DNIPTIDPTGLTTNPPTAAESDLLKPVPADALGLSGNDTPGPSHNTALARGTGQPGSRPT
       ..  .  :. ....   :. :   .:.: .. .:: . . :   . .: . .. :  . .
XP_005 SEAESTPPSFMSVHAQLAG-SLGGQPAPIQTQSLSHDPVSG---TQGLEKKVS-PDPQKS
            1440      1450       1460      1470         1480       

        540       550       560       570            580           
pF1KSD WPSQCLEELVQELARLDPSLCDPLASQPSPEPPLGLLDGLIP-----LAEV---RAAMRP
         .   : :..:... : :: : :  .   .  . :..::.:     : :    : :.. 
XP_005 SEDIRTEALAKEIVHQDKSLADILDPDSRLKTTMDLMEGLFPRDVNLLKENSVKRKAIQR
       1490      1500      1510      1520      1530      1540      

      590       600       610       620       630       640        
pF1KSD ACGEAGEEAASTFEPGSYQFSFTQLLPAPREETRLENPATHPVLDQPCGQGLPAPNNSIQ
       . . .: :.  . .  .   :.    ::    .  .    . . ..:   .    . ...
XP_005 TVSSSGCEGKRNEDKEAV--SMLVNCPAYYSVSAPKAELLNKIKEMPAEVNEEEEQADVN
       1550      1560        1570      1580      1590      1600    

      650       660       670       680       690       700        
pF1KSD GKKVELAARLQKMLQDLHTEQERLQGEAQAWARRQAALEAAVRQACAPQELERFSRFMAD
        ::.:: . : . :. :.  .  :  . .        .:: . . : :.:....  :..:
XP_005 EKKAELIGSLTHKLETLQEAKGSLLTDIKLNNALGEEVEALISELCKPNEFDKYRMFIGD
         1610      1620      1630      1640      1650      1660    

      710       720       730       740       750       760        
pF1KSD LERVLGLLLLLGSRLARVRRALARAASDSDPDEQASLLQRLRLLQRQEEDAKELKEHVAR
       :..:..::: :..:::::. .:.  . :.. .:..:: .. ..:  :.:::.::::.. :
XP_005 LDKVVNLLLSLSGRLARVENVLSGLGEDASNEERSSLYEKRKILAGQHEDARELKENLDR
         1670      1680      1690      1700      1710      1720    

      770       780       790       800       810       820        
pF1KSD RERAVREVLVRALPVEELRVYCALLAGKAAVLAQQRNLDERIRLLQDQLDAIRDDL-GHH
       :::.:  .:.  :  :.:. :  ..  :...: .::.::..:.: :.:.  . ..: .  
XP_005 RERVVLGILANYLSEEQLQDYQHFVKMKSTLLIEQRKLDDKIKLGQEQVKCLLESLPSDF
         1730      1740      1750      1760      1770      1780    

       830         840       850           
pF1KSD APSPSP-ARPPG-TCPPVQPPFPLLLT         
        :. .  : ::. :  :.                  
XP_005 IPKAGALALPPNLTSEPIPAGGCTFSGIFPTLTSPL
         1790      1800      1810      1820

>>XP_011530463 (OMIM: 604570) PREDICTED: protein Shroom3  (1820 aa)
 initn: 621 init1: 352 opt: 422  Z-score: 264.0  bits: 61.0 E(85289): 5.8e-08
Smith-Waterman score: 494; 23.1% identity (50.1% similar) in 888 aa overlap (5-843:948-1802)

                                            10        20        30 
pF1KSD                           MEALGPG---GDRASPASSTSSLDLWHLSMRADS
                                     ::.   :.  . ::: :::    :. : ..
XP_011 TGKRPTSAAGCSLQEPGPLRERAQSAYLQPGPAALEGSGLASASSLSSLREPSLQPRREA
       920       930       940       950       960       970       

              40        50            60        70             80  
pF1KSD AYSSFSAASGGPEPRTQSP----GTDLLPYLDWDYVRVVWGGP-----GPAPPDAALCTS
       .    ..:     :: .:     :  :      : .  . ::      :   :      .
XP_011 TLLPATVAETQQAPRDRSSSFAGGRRLGERRRGDLLSGANGGTRGTQRGDETPREPSSWG
       980       990      1000      1010      1020      1030       

             90       100       110       120       130       140  
pF1KSD PRPRPAVAARSGPQPTEVPGTPGPLNRQATPLLYALAAEAEAAAQAAEPPSPPASRAAYR
        :   ...:..  . ..: . :  .  ...:   : : . . .  . .     ..   : 
XP_011 ARAGKSMSAEDLLERSDVLAGPVHVRSRSSP---ATADKRQDVLLGQDSGFGLVKDPCY-
      1040      1050      1060         1070      1080      1090    

            150       160       170        180       190        200
pF1KSD QRLQGAQRRVLRETSFQRKELRMSLPARLRPTVPARP-PATHPRSASLSHPGG-EGEPAR
         : :   : :  .   ..:. . :  .: :   .    :    :.    ::  . .   
XP_011 --LAGPGSRSLSCSERGQEEM-LPLFHHLTPRWGGSGCKAIGDSSVPSECPGTLDHQRQA
            1100      1110       1120      1130      1140      1150

              210       220       230       240        250         
pF1KSD SRAPAPGTAGRGPLANQQRKWCFSEPGKLDRVGRGGGPARECLGEA-CSSSGLPGPEPLE
       ::.: :    : :::. :     .. . :  .:    :    .  . ::..:  : .:: 
XP_011 SRTPCP----RPPLAGTQGLVTDTRAAPLTPIGT---PLPSAIPSGYCSQDGQTGRQPLP
                 1160      1170      1180         1190      1200   

     260       270       280       290       300       310         
pF1KSD FQHPALAKFEDHEVGWLPETQPQGSMNLDSGSLKLGDAFRPASRSRSASGE----VLGSW
          ::.     :. .    ::: :  . .. . . :   . ..:.: .  .      ..:
XP_011 PYTPAMM----HRSNGHTLTQPPGPRGCEGDGPEHG--VEEGTRKRVSLPQWPPPSRAKW
          1210          1220      1230        1240      1250       

           320       330       340       350       360       370   
pF1KSD GGSG--GTIPIVQAVPQGAETPRPLFQTKLSRFLPQKEAAVMYPAELPQSSPADSEQRVS
       . ..   ..:  ...:. :.  .   : .:  .   ..  .  :   : :.:.    :.:
XP_011 AHAAREDSLPEESSAPDFANLKHYQKQQSLPSLCSTSDPDT--PLGAP-STPGRISLRIS
      1260      1270      1280      1290        1300       1310    

           380         390               400       410       420   
pF1KSD ETCIVPAWLP--SLPDEVFLEE-------APLVR-MRSPPDPHASQGPPASVHASDQPYG
       :. .  .  :  .  ::::...       .:  . .  :: :  ::  :  :.. :. . 
XP_011 ESVLRDSPPPHEDYEDEVFVRDPHPKATSSPTFEPLPPPPPPPPSQETP--VYSMDD-FP
         1320      1330      1340      1350      1360         1370 

           430       440              450       460       470      
pF1KSD TGLGQRTGQVTVPTEYPLHECPG-------TAGADDCWQGVNGSVGISRPTSHTPTGTAN
           . . .. . .: :    :.       : . .    :.   :: .  .:.  :.  .
XP_011 PPPPHTVCEAQLDSEDPEGPRPSFNKLSKVTIARERHMPGAAHVVGSQTLASRLQTSIKG
            1380      1390      1400      1410      1420      1430 

        480       490       500       510       520       530      
pF1KSD DNIPTIDPTGLTTNPPTAAESDLLKPVPADALGLSGNDTPGPSHNTALARGTGQPGSRPT
       ..  .  :. ....   :. :   .:.: .. .:: . . :   . .: . .. :  . .
XP_011 SEAESTPPSFMSVHAQLAG-SLGGQPAPIQTQSLSHDPVSG---TQGLEKKVS-PDPQKS
            1440      1450       1460      1470         1480       

        540       550       560       570            580           
pF1KSD WPSQCLEELVQELARLDPSLCDPLASQPSPEPPLGLLDGLIP-----LAEV---RAAMRP
         .   : :..:... : :: : :  .   .  . :..::.:     : :    : :.. 
XP_011 SEDIRTEALAKEIVHQDKSLADILDPDSRLKTTMDLMEGLFPRDVNLLKENSVKRKAIQR
       1490      1500      1510      1520      1530      1540      

      590       600       610       620       630       640        
pF1KSD ACGEAGEEAASTFEPGSYQFSFTQLLPAPREETRLENPATHPVLDQPCGQGLPAPNNSIQ
       . . .: :.  . .  .   :.    ::    .  .    . . ..:   .    . ...
XP_011 TVSSSGCEGKRNEDKEAV--SMLVNCPAYYSVSAPKAELLNKIKEMPAEVNEEEEQADVN
       1550      1560        1570      1580      1590      1600    

      650       660       670       680       690       700        
pF1KSD GKKVELAARLQKMLQDLHTEQERLQGEAQAWARRQAALEAAVRQACAPQELERFSRFMAD
        ::.:: . : . :. :.  .  :  . .        .:: . . : :.:....  :..:
XP_011 EKKAELIGSLTHKLETLQEAKGSLLTDIKLNNALGEEVEALISELCKPNEFDKYRMFIGD
         1610      1620      1630      1640      1650      1660    

      710       720       730       740       750       760        
pF1KSD LERVLGLLLLLGSRLARVRRALARAASDSDPDEQASLLQRLRLLQRQEEDAKELKEHVAR
       :..:..::: :..:::::. .:.  . :.. .:..:: .. ..:  :.:::.::::.. :
XP_011 LDKVVNLLLSLSGRLARVENVLSGLGEDASNEERSSLYEKRKILAGQHEDARELKENLDR
         1670      1680      1690      1700      1710      1720    

      770       780       790       800       810       820        
pF1KSD RERAVREVLVRALPVEELRVYCALLAGKAAVLAQQRNLDERIRLLQDQLDAIRDDL-GHH
       :::.:  .:.  :  :.:. :  ..  :...: .::.::..:.: :.:.  . ..: .  
XP_011 RERVVLGILANYLSEEQLQDYQHFVKMKSTLLIEQRKLDDKIKLGQEQVKCLLESLPSDF
         1730      1740      1750      1760      1770      1780    

       830         840       850           
pF1KSD APSPSP-ARPPG-TCPPVQPPFPLLLT         
        :. .  : ::. :  :.                  
XP_011 IPKAGALALPPNLTSEPIPAGGCTFSGIFPTLTSPL
         1790      1800      1810      1820

>>XP_005263221 (OMIM: 604570) PREDICTED: protein Shroom3  (1820 aa)
 initn: 621 init1: 352 opt: 422  Z-score: 264.0  bits: 61.0 E(85289): 5.8e-08
Smith-Waterman score: 494; 23.1% identity (50.1% similar) in 888 aa overlap (5-843:948-1802)

                                            10        20        30 
pF1KSD                           MEALGPG---GDRASPASSTSSLDLWHLSMRADS
                                     ::.   :.  . ::: :::    :. : ..
XP_005 TGKRPTSAAGCSLQEPGPLRERAQSAYLQPGPAALEGSGLASASSLSSLREPSLQPRREA
       920       930       940       950       960       970       

              40        50            60        70             80  
pF1KSD AYSSFSAASGGPEPRTQSP----GTDLLPYLDWDYVRVVWGGP-----GPAPPDAALCTS
       .    ..:     :: .:     :  :      : .  . ::      :   :      .
XP_005 TLLPATVAETQQAPRDRSSSFAGGRRLGERRRGDLLSGANGGTRGTQRGDETPREPSSWG
       980       990      1000      1010      1020      1030       

             90       100       110       120       130       140  
pF1KSD PRPRPAVAARSGPQPTEVPGTPGPLNRQATPLLYALAAEAEAAAQAAEPPSPPASRAAYR
        :   ...:..  . ..: . :  .  ...:   : : . . .  . .     ..   : 
XP_005 ARAGKSMSAEDLLERSDVLAGPVHVRSRSSP---ATADKRQDVLLGQDSGFGLVKDPCY-
      1040      1050      1060         1070      1080      1090    

            150       160       170        180       190        200
pF1KSD QRLQGAQRRVLRETSFQRKELRMSLPARLRPTVPARP-PATHPRSASLSHPGG-EGEPAR
         : :   : :  .   ..:. . :  .: :   .    :    :.    ::  . .   
XP_005 --LAGPGSRSLSCSERGQEEM-LPLFHHLTPRWGGSGCKAIGDSSVPSECPGTLDHQRQA
            1100      1110       1120      1130      1140      1150

              210       220       230       240        250         
pF1KSD SRAPAPGTAGRGPLANQQRKWCFSEPGKLDRVGRGGGPARECLGEA-CSSSGLPGPEPLE
       ::.: :    : :::. :     .. . :  .:    :    .  . ::..:  : .:: 
XP_005 SRTPCP----RPPLAGTQGLVTDTRAAPLTPIGT---PLPSAIPSGYCSQDGQTGRQPLP
                 1160      1170      1180         1190      1200   

     260       270       280       290       300       310         
pF1KSD FQHPALAKFEDHEVGWLPETQPQGSMNLDSGSLKLGDAFRPASRSRSASGE----VLGSW
          ::.     :. .    ::: :  . .. . . :   . ..:.: .  .      ..:
XP_005 PYTPAMM----HRSNGHTLTQPPGPRGCEGDGPEHG--VEEGTRKRVSLPQWPPPSRAKW
          1210          1220      1230        1240      1250       

           320       330       340       350       360       370   
pF1KSD GGSG--GTIPIVQAVPQGAETPRPLFQTKLSRFLPQKEAAVMYPAELPQSSPADSEQRVS
       . ..   ..:  ...:. :.  .   : .:  .   ..  .  :   : :.:.    :.:
XP_005 AHAAREDSLPEESSAPDFANLKHYQKQQSLPSLCSTSDPDT--PLGAP-STPGRISLRIS
      1260      1270      1280      1290        1300       1310    

           380         390               400       410       420   
pF1KSD ETCIVPAWLP--SLPDEVFLEE-------APLVR-MRSPPDPHASQGPPASVHASDQPYG
       :. .  .  :  .  ::::...       .:  . .  :: :  ::  :  :.. :. . 
XP_005 ESVLRDSPPPHEDYEDEVFVRDPHPKATSSPTFEPLPPPPPPPPSQETP--VYSMDD-FP
         1320      1330      1340      1350      1360         1370 

           430       440              450       460       470      
pF1KSD TGLGQRTGQVTVPTEYPLHECPG-------TAGADDCWQGVNGSVGISRPTSHTPTGTAN
           . . .. . .: :    :.       : . .    :.   :: .  .:.  :.  .
XP_005 PPPPHTVCEAQLDSEDPEGPRPSFNKLSKVTIARERHMPGAAHVVGSQTLASRLQTSIKG
            1380      1390      1400      1410      1420      1430 

        480       490       500       510       520       530      
pF1KSD DNIPTIDPTGLTTNPPTAAESDLLKPVPADALGLSGNDTPGPSHNTALARGTGQPGSRPT
       ..  .  :. ....   :. :   .:.: .. .:: . . :   . .: . .. :  . .
XP_005 SEAESTPPSFMSVHAQLAG-SLGGQPAPIQTQSLSHDPVSG---TQGLEKKVS-PDPQKS
            1440      1450       1460      1470         1480       

        540       550       560       570            580           
pF1KSD WPSQCLEELVQELARLDPSLCDPLASQPSPEPPLGLLDGLIP-----LAEV---RAAMRP
         .   : :..:... : :: : :  .   .  . :..::.:     : :    : :.. 
XP_005 SEDIRTEALAKEIVHQDKSLADILDPDSRLKTTMDLMEGLFPRDVNLLKENSVKRKAIQR
       1490      1500      1510      1520      1530      1540      

      590       600       610       620       630       640        
pF1KSD ACGEAGEEAASTFEPGSYQFSFTQLLPAPREETRLENPATHPVLDQPCGQGLPAPNNSIQ
       . . .: :.  . .  .   :.    ::    .  .    . . ..:   .    . ...
XP_005 TVSSSGCEGKRNEDKEAV--SMLVNCPAYYSVSAPKAELLNKIKEMPAEVNEEEEQADVN
       1550      1560        1570      1580      1590      1600    

      650       660       670       680       690       700        
pF1KSD GKKVELAARLQKMLQDLHTEQERLQGEAQAWARRQAALEAAVRQACAPQELERFSRFMAD
        ::.:: . : . :. :.  .  :  . .        .:: . . : :.:....  :..:
XP_005 EKKAELIGSLTHKLETLQEAKGSLLTDIKLNNALGEEVEALISELCKPNEFDKYRMFIGD
         1610      1620      1630      1640      1650      1660    

      710       720       730       740       750       760        
pF1KSD LERVLGLLLLLGSRLARVRRALARAASDSDPDEQASLLQRLRLLQRQEEDAKELKEHVAR
       :..:..::: :..:::::. .:.  . :.. .:..:: .. ..:  :.:::.::::.. :
XP_005 LDKVVNLLLSLSGRLARVENVLSGLGEDASNEERSSLYEKRKILAGQHEDARELKENLDR
         1670      1680      1690      1700      1710      1720    

      770       780       790       800       810       820        
pF1KSD RERAVREVLVRALPVEELRVYCALLAGKAAVLAQQRNLDERIRLLQDQLDAIRDDL-GHH
       :::.:  .:.  :  :.:. :  ..  :...: .::.::..:.: :.:.  . ..: .  
XP_005 RERVVLGILANYLSEEQLQDYQHFVKMKSTLLIEQRKLDDKIKLGQEQVKCLLESLPSDF
         1730      1740      1750      1760      1770      1780    

       830         840       850           
pF1KSD APSPSP-ARPPG-TCPPVQPPFPLLLT         
        :. .  : ::. :  :.                  
XP_005 IPKAGALALPPNLTSEPIPAGGCTFSGIFPTLTSPL
         1790      1800      1810      1820

>>XP_005263220 (OMIM: 604570) PREDICTED: protein Shroom3  (1820 aa)
 initn: 621 init1: 352 opt: 422  Z-score: 264.0  bits: 61.0 E(85289): 5.8e-08
Smith-Waterman score: 494; 23.1% identity (50.1% similar) in 888 aa overlap (5-843:948-1802)

                                            10        20        30 
pF1KSD                           MEALGPG---GDRASPASSTSSLDLWHLSMRADS
                                     ::.   :.  . ::: :::    :. : ..
XP_005 TGKRPTSAAGCSLQEPGPLRERAQSAYLQPGPAALEGSGLASASSLSSLREPSLQPRREA
       920       930       940       950       960       970       

              40        50            60        70             80  
pF1KSD AYSSFSAASGGPEPRTQSP----GTDLLPYLDWDYVRVVWGGP-----GPAPPDAALCTS
       .    ..:     :: .:     :  :      : .  . ::      :   :      .
XP_005 TLLPATVAETQQAPRDRSSSFAGGRRLGERRRGDLLSGANGGTRGTQRGDETPREPSSWG
       980       990      1000      1010      1020      1030       

             90       100       110       120       130       140  
pF1KSD PRPRPAVAARSGPQPTEVPGTPGPLNRQATPLLYALAAEAEAAAQAAEPPSPPASRAAYR
        :   ...:..  . ..: . :  .  ...:   : : . . .  . .     ..   : 
XP_005 ARAGKSMSAEDLLERSDVLAGPVHVRSRSSP---ATADKRQDVLLGQDSGFGLVKDPCY-
      1040      1050      1060         1070      1080      1090    

            150       160       170        180       190        200
pF1KSD QRLQGAQRRVLRETSFQRKELRMSLPARLRPTVPARP-PATHPRSASLSHPGG-EGEPAR
         : :   : :  .   ..:. . :  .: :   .    :    :.    ::  . .   
XP_005 --LAGPGSRSLSCSERGQEEM-LPLFHHLTPRWGGSGCKAIGDSSVPSECPGTLDHQRQA
            1100      1110       1120      1130      1140      1150

              210       220       230       240        250         
pF1KSD SRAPAPGTAGRGPLANQQRKWCFSEPGKLDRVGRGGGPARECLGEA-CSSSGLPGPEPLE
       ::.: :    : :::. :     .. . :  .:    :    .  . ::..:  : .:: 
XP_005 SRTPCP----RPPLAGTQGLVTDTRAAPLTPIGT---PLPSAIPSGYCSQDGQTGRQPLP
                 1160      1170      1180         1190      1200   

     260       270       280       290       300       310         
pF1KSD FQHPALAKFEDHEVGWLPETQPQGSMNLDSGSLKLGDAFRPASRSRSASGE----VLGSW
          ::.     :. .    ::: :  . .. . . :   . ..:.: .  .      ..:
XP_005 PYTPAMM----HRSNGHTLTQPPGPRGCEGDGPEHG--VEEGTRKRVSLPQWPPPSRAKW
          1210          1220      1230        1240      1250       

           320       330       340       350       360       370   
pF1KSD GGSG--GTIPIVQAVPQGAETPRPLFQTKLSRFLPQKEAAVMYPAELPQSSPADSEQRVS
       . ..   ..:  ...:. :.  .   : .:  .   ..  .  :   : :.:.    :.:
XP_005 AHAAREDSLPEESSAPDFANLKHYQKQQSLPSLCSTSDPDT--PLGAP-STPGRISLRIS
      1260      1270      1280      1290        1300       1310    

           380         390               400       410       420   
pF1KSD ETCIVPAWLP--SLPDEVFLEE-------APLVR-MRSPPDPHASQGPPASVHASDQPYG
       :. .  .  :  .  ::::...       .:  . .  :: :  ::  :  :.. :. . 
XP_005 ESVLRDSPPPHEDYEDEVFVRDPHPKATSSPTFEPLPPPPPPPPSQETP--VYSMDD-FP
         1320      1330      1340      1350      1360         1370 

           430       440              450       460       470      
pF1KSD TGLGQRTGQVTVPTEYPLHECPG-------TAGADDCWQGVNGSVGISRPTSHTPTGTAN
           . . .. . .: :    :.       : . .    :.   :: .  .:.  :.  .
XP_005 PPPPHTVCEAQLDSEDPEGPRPSFNKLSKVTIARERHMPGAAHVVGSQTLASRLQTSIKG
            1380      1390      1400      1410      1420      1430 

        480       490       500       510       520       530      
pF1KSD DNIPTIDPTGLTTNPPTAAESDLLKPVPADALGLSGNDTPGPSHNTALARGTGQPGSRPT
       ..  .  :. ....   :. :   .:.: .. .:: . . :   . .: . .. :  . .
XP_005 SEAESTPPSFMSVHAQLAG-SLGGQPAPIQTQSLSHDPVSG---TQGLEKKVS-PDPQKS
            1440      1450       1460      1470         1480       

        540       550       560       570            580           
pF1KSD WPSQCLEELVQELARLDPSLCDPLASQPSPEPPLGLLDGLIP-----LAEV---RAAMRP
         .   : :..:... : :: : :  .   .  . :..::.:     : :    : :.. 
XP_005 SEDIRTEALAKEIVHQDKSLADILDPDSRLKTTMDLMEGLFPRDVNLLKENSVKRKAIQR
       1490      1500      1510      1520      1530      1540      

      590       600       610       620       630       640        
pF1KSD ACGEAGEEAASTFEPGSYQFSFTQLLPAPREETRLENPATHPVLDQPCGQGLPAPNNSIQ
       . . .: :.  . .  .   :.    ::    .  .    . . ..:   .    . ...
XP_005 TVSSSGCEGKRNEDKEAV--SMLVNCPAYYSVSAPKAELLNKIKEMPAEVNEEEEQADVN
       1550      1560        1570      1580      1590      1600    

      650       660       670       680       690       700        
pF1KSD GKKVELAARLQKMLQDLHTEQERLQGEAQAWARRQAALEAAVRQACAPQELERFSRFMAD
        ::.:: . : . :. :.  .  :  . .        .:: . . : :.:....  :..:
XP_005 EKKAELIGSLTHKLETLQEAKGSLLTDIKLNNALGEEVEALISELCKPNEFDKYRMFIGD
         1610      1620      1630      1640      1650      1660    

      710       720       730       740       750       760        
pF1KSD LERVLGLLLLLGSRLARVRRALARAASDSDPDEQASLLQRLRLLQRQEEDAKELKEHVAR
       :..:..::: :..:::::. .:.  . :.. .:..:: .. ..:  :.:::.::::.. :
XP_005 LDKVVNLLLSLSGRLARVENVLSGLGEDASNEERSSLYEKRKILAGQHEDARELKENLDR
         1670      1680      1690      1700      1710      1720    

      770       780       790       800       810       820        
pF1KSD RERAVREVLVRALPVEELRVYCALLAGKAAVLAQQRNLDERIRLLQDQLDAIRDDL-GHH
       :::.:  .:.  :  :.:. :  ..  :...: .::.::..:.: :.:.  . ..: .  
XP_005 RERVVLGILANYLSEEQLQDYQHFVKMKSTLLIEQRKLDDKIKLGQEQVKCLLESLPSDF
         1730      1740      1750      1760      1770      1780    

       830         840       850           
pF1KSD APSPSP-ARPPG-TCPPVQPPFPLLLT         
        :. .  : ::. :  :.                  
XP_005 IPKAGALALPPNLTSEPIPAGGCTFSGIFPTLTSPL
         1790      1800      1810      1820




852 residues in 1 query   sequences
60827320 residues in 85289 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Thu Nov  3 07:49:54 2016 done: Thu Nov  3 07:49:56 2016
 Total Scan time: 15.800 Total Display time:  0.260

Function used was FASTA [36.3.4 Apr, 2011]
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