Result of FASTA (omim) for pF1KSDA1792
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KSDA1792, 764 aa
  1>>>pF1KSDA1792 764 - 764 aa - 764 aa
Library: /omim/omim.rfq.tfa
  60827320 residues in 85289 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 5.4071+/-0.000431; mu= 19.4330+/- 0.027
 mean_var=70.5673+/-14.314, 0's: 0 Z-trim(109.8): 36  B-trim: 0 in 0/52
 Lambda= 0.152677
 statistics sampled from 18015 (18039) to 18015 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.574), E-opt: 0.2 (0.212), width:  16
 Scan time: 11.840

The best scores are:                                      opt bits E(85289)
NP_068598 (OMIM: 614272) FAST kinase domain-contai ( 764) 5063 1125.2       0
XP_011514064 (OMIM: 606965) PREDICTED: fas-activat ( 462)  180 49.6 3.6e-05
XP_011514063 (OMIM: 606965) PREDICTED: fas-activat ( 494)  180 49.6 3.8e-05
XP_005249989 (OMIM: 606965) PREDICTED: fas-activat ( 515)  180 49.6   4e-05
XP_005249990 (OMIM: 606965) PREDICTED: fas-activat ( 515)  180 49.6   4e-05
NP_006703 (OMIM: 606965) fas-activated serine/thre ( 549)  180 49.6 4.2e-05
XP_016867194 (OMIM: 606965) PREDICTED: fas-activat ( 353)  177 48.8 4.6e-05
NP_148936 (OMIM: 606965) fas-activated serine/thre ( 408)  177 48.9 5.2e-05
XP_011514065 (OMIM: 606965) PREDICTED: fas-activat ( 381)  162 45.5 0.00048
XP_016867193 (OMIM: 606965) PREDICTED: fas-activat ( 488)  162 45.6 0.00059
NP_001245390 (OMIM: 606965) fas-activated serine/t ( 522)  162 45.6 0.00063
XP_016867195 (OMIM: 606965) PREDICTED: fas-activat ( 310)  155 44.0  0.0012
NP_004740 (OMIM: 611325) protein TBRG4 isoform 1 [ ( 631)  146 42.2  0.0084
NP_001248763 (OMIM: 611325) protein TBRG4 isoform  ( 642)  146 42.2  0.0085


>>NP_068598 (OMIM: 614272) FAST kinase domain-containing  (764 aa)
 initn: 5063 init1: 5063 opt: 5063  Z-score: 6023.3  bits: 1125.2 E(85289):    0
Smith-Waterman score: 5063; 100.0% identity (100.0% similar) in 764 aa overlap (1-764:1-764)

               10        20        30        40        50        60
pF1KSD MAATLKSLKLVRYRAFCSPSAFGAVRSVSYWNVSSTQHGGQDPPEHISLCHSAKKVKNIC
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_068 MAATLKSLKLVRYRAFCSPSAFGAVRSVSYWNVSSTQHGGQDPPEHISLCHSAKKVKNIC
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KSD STFSSRRILTTSSAHPGLEFSKTSSSKASTLQLGSPRATGVDEEDVEVFDSFENMRVFLQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_068 STFSSRRILTTSSAHPGLEFSKTSSSKASTLQLGSPRATGVDEEDVEVFDSFENMRVFLQ
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KSD LRPEYRVHSYNASETSQLLSVSEGELILHKVRVNQNNLQAQVIVDYLCKLSSLPAEQHPV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_068 LRPEYRVHSYNASETSQLLSVSEGELILHKVRVNQNNLQAQVIVDYLCKLSSLPAEQHPV
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KSD LLGSTSFALLCQLSVKKIQLFDTQDLINVLKAFVILGIPHSHSMLDVYETKCCHQVWEMN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_068 LLGSTSFALLCQLSVKKIQLFDTQDLINVLKAFVILGIPHSHSMLDVYETKCCHQVWEMN
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KSD MDQLLLVADLWRYLGRKVPRFLNIFSSYLNLHWKDLSLSQLVHLIYVIGENRQVSQDLMQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_068 MDQLLLVADLWRYLGRKVPRFLNIFSSYLNLHWKDLSLSQLVHLIYVIGENRQVSQDLMQ
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KSD KLESLILKYIDLINLEEVGTICLGFFKSSTNLSEFVMRKIGDLACANIQHLSSRSLVNIV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_068 KLESLILKYIDLINLEEVGTICLGFFKSSTNLSEFVMRKIGDLACANIQHLSSRSLVNIV
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KSD KMFRFTHVDHINFMKQIGEIAPQRIPSLGVQGVMHLTLYCSALRFLNEGVMNAVAASLPP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_068 KMFRFTHVDHINFMKQIGEIAPQRIPSLGVQGVMHLTLYCSALRFLNEGVMNAVAASLPP
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KSD RVAHCRSKDVAKILWSFGTLNYKPPNAEEFYSSLISEIHRKMPEFNQYPEHLPTCLLGLA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_068 RVAHCRSKDVAKILWSFGTLNYKPPNAEEFYSSLISEIHRKMPEFNQYPEHLPTCLLGLA
              430       440       450       460       470       480

              490       500       510       520       530       540
pF1KSD FLEYFPVELIDFALSPGFVRLAQERTKFDLLKELYTLDGTVGIECPDYRGNRLSTHLQQE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_068 FLEYFPVELIDFALSPGFVRLAQERTKFDLLKELYTLDGTVGIECPDYRGNRLSTHLQQE
              490       500       510       520       530       540

              550       560       570       580       590       600
pF1KSD GSELLWYLAEKDMNSKPEFLETVFLLETMLGGPQYVKHHMILPHTRSSDLEVQLDVNLKP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_068 GSELLWYLAEKDMNSKPEFLETVFLLETMLGGPQYVKHHMILPHTRSSDLEVQLDVNLKP
              550       560       570       580       590       600

              610       620       630       640       650       660
pF1KSD LPFNREATPAENVAKLRLEHVGVSLTDDLMNKLLKGKARGHFQGKTESEPGQQPMELENK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_068 LPFNREATPAENVAKLRLEHVGVSLTDDLMNKLLKGKARGHFQGKTESEPGQQPMELENK
              610       620       630       640       650       660

              670       680       690       700       710       720
pF1KSD AAVPLGGFLCNVADKSGAMEMAGLCPAACMQTPRMKLAVQFTNRNQYCYGSRDLLGLHNM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_068 AAVPLGGFLCNVADKSGAMEMAGLCPAACMQTPRMKLAVQFTNRNQYCYGSRDLLGLHNM
              670       680       690       700       710       720

              730       740       750       760    
pF1KSD KRRQLARLGYRVVELSYWEWLPLLKRTRLEKLAFLHEKVFTSAL
       ::::::::::::::::::::::::::::::::::::::::::::
NP_068 KRRQLARLGYRVVELSYWEWLPLLKRTRLEKLAFLHEKVFTSAL
              730       740       750       760    

>>XP_011514064 (OMIM: 606965) PREDICTED: fas-activated s  (462 aa)
 initn: 144 init1:  64 opt: 180  Z-score: 213.8  bits: 49.6 E(85289): 3.6e-05
Smith-Waterman score: 180; 24.2% identity (53.2% similar) in 293 aa overlap (260-538:100-382)

     230       240       250       260       270       280         
pF1KSD TKCCHQVWEMNMDQLLLVADLWRYLGRKVPRFLNIFSSYLNLHWKDLSLSQLVHLIYVIG
                                     :.:.   : .  :  ...: .: .:.    
XP_011 DRPVGGGPSAGPVQGLQRLLEQAKSPGELLRWLGQNPSKVRAHHYSVALRRLGQLLGSRP
      70        80        90       100       110       120         

     290       300       310       320            330              
pF1KSD ENRQVSQDLMQKLESLILKYIDLINLEEVGTICLGF-----FKSSTNL-----SEFVMRK
       .   : :  .: : .::..    .... .  .:: .     : :.  :     .:  .: 
XP_011 RPPPVEQVTLQDLSQLIIRNCPSFDIHTIH-VCLHLAVLLGFPSDGPLVCALEQERRLR-
     130       140       150        160       170       180        

     340       350         360       370       380        390      
pF1KSD IGDLACANIQHL--SSRSLVNIVKMFRFTHVDHINFMKQIGEIAPQRI-PSLGVQGVMHL
       .       .: :  ....:   ..  :: .  . .......:  :... : . :  ..::
XP_011 LPPKPPPPLQPLLRGGQGLEAALSCPRFLRYPRQHLISSLAEARPEELTPHVMVLLAQHL
       190       200       210       220       230       240       

        400       410       420       430       440       450      
pF1KSD TLYCSALRFLNEGVMNAVAASLPPRVAHCRSKDVAKILWSFGTLNYKPPNAEEFYSSLIS
       . .    :. .  ...:.:  :  . ..  :: : :..  :: ::: : . ..:.  :  
XP_011 ARH----RLREPQLLEAIAHFLVVQETQLSSKVVQKLVLPFGRLNYLPLE-QQFMPCLER
       250           260       270       280       290        300  

        460       470       480       490       500       510      
pF1KSD EIHRKMPEFNQYPEHLPTCLLGLAFLEYFPVELIDFALSPGFVRLAQERTKFDLLKE-LY
        . :   : .  :    . :..:  :. .: . . :..::::.   .   .  .... : 
XP_011 ILAR---EAGVAPLATVNILMSLCQLRCLPFRALHFVFSPGFINYISGTPHALIVRRYLS
               310       320       330       340       350         

         520       530       540       550       560       570     
pF1KSD TLDGTVGIECPDYRGNRLSTHLQQEGSELLWYLAEKDMNSKPEFLETVFLLETMLGGPQY
        :: .: .: : ::: ::  . :                                     
XP_011 LLDTAVELELPGYRGPRLPRRQQVPIFPQPLITDRARCKYSHKDIVAEGLRQLLGEEKYR
     360       370       380       390       400       410         

>>XP_011514063 (OMIM: 606965) PREDICTED: fas-activated s  (494 aa)
 initn: 144 init1:  64 opt: 180  Z-score: 213.3  bits: 49.6 E(85289): 3.8e-05
Smith-Waterman score: 180; 24.2% identity (53.2% similar) in 293 aa overlap (260-538:100-382)

     230       240       250       260       270       280         
pF1KSD TKCCHQVWEMNMDQLLLVADLWRYLGRKVPRFLNIFSSYLNLHWKDLSLSQLVHLIYVIG
                                     :.:.   : .  :  ...: .: .:.    
XP_011 DRPVGGGPSAGPVQGLQRLLEQAKSPGELLRWLGQNPSKVRAHHYSVALRRLGQLLGSRP
      70        80        90       100       110       120         

     290       300       310       320            330              
pF1KSD ENRQVSQDLMQKLESLILKYIDLINLEEVGTICLGF-----FKSSTNL-----SEFVMRK
       .   : :  .: : .::..    .... .  .:: .     : :.  :     .:  .: 
XP_011 RPPPVEQVTLQDLSQLIIRNCPSFDIHTIH-VCLHLAVLLGFPSDGPLVCALEQERRLR-
     130       140       150        160       170       180        

     340       350         360       370       380        390      
pF1KSD IGDLACANIQHL--SSRSLVNIVKMFRFTHVDHINFMKQIGEIAPQRI-PSLGVQGVMHL
       .       .: :  ....:   ..  :: .  . .......:  :... : . :  ..::
XP_011 LPPKPPPPLQPLLRGGQGLEAALSCPRFLRYPRQHLISSLAEARPEELTPHVMVLLAQHL
       190       200       210       220       230       240       

        400       410       420       430       440       450      
pF1KSD TLYCSALRFLNEGVMNAVAASLPPRVAHCRSKDVAKILWSFGTLNYKPPNAEEFYSSLIS
       . .    :. .  ...:.:  :  . ..  :: : :..  :: ::: : . ..:.  :  
XP_011 ARH----RLREPQLLEAIAHFLVVQETQLSSKVVQKLVLPFGRLNYLPLE-QQFMPCLER
       250           260       270       280       290        300  

        460       470       480       490       500       510      
pF1KSD EIHRKMPEFNQYPEHLPTCLLGLAFLEYFPVELIDFALSPGFVRLAQERTKFDLLKE-LY
        . :   : .  :    . :..:  :. .: . . :..::::.   .   .  .... : 
XP_011 ILAR---EAGVAPLATVNILMSLCQLRCLPFRALHFVFSPGFINYISGTPHALIVRRYLS
               310       320       330       340       350         

         520       530       540       550       560       570     
pF1KSD TLDGTVGIECPDYRGNRLSTHLQQEGSELLWYLAEKDMNSKPEFLETVFLLETMLGGPQY
        :: .: .: : ::: ::  . :                                     
XP_011 LLDTAVELELPGYRGPRLPRRQQVPIFPQPLITDRARCKYSHKDIVAEGLRQLLGEEKYR
     360       370       380       390       400       410         

>>XP_005249989 (OMIM: 606965) PREDICTED: fas-activated s  (515 aa)
 initn: 144 init1:  64 opt: 180  Z-score: 213.1  bits: 49.6 E(85289): 4e-05
Smith-Waterman score: 180; 24.2% identity (53.2% similar) in 293 aa overlap (260-538:66-348)

     230       240       250       260       270       280         
pF1KSD TKCCHQVWEMNMDQLLLVADLWRYLGRKVPRFLNIFSSYLNLHWKDLSLSQLVHLIYVIG
                                     :.:.   : .  :  ...: .: .:.    
XP_005 DRPVGGGPSAGPVQGLQRLLEQAKSPGELLRWLGQNPSKVRAHHYSVALRRLGQLLGSRP
          40        50        60        70        80        90     

     290       300       310       320            330              
pF1KSD ENRQVSQDLMQKLESLILKYIDLINLEEVGTICLGF-----FKSSTNL-----SEFVMRK
       .   : :  .: : .::..    .... .  .:: .     : :.  :     .:  .: 
XP_005 RPPPVEQVTLQDLSQLIIRNCPSFDIHTIH-VCLHLAVLLGFPSDGPLVCALEQERRLR-
         100       110       120        130       140       150    

     340       350         360       370       380        390      
pF1KSD IGDLACANIQHL--SSRSLVNIVKMFRFTHVDHINFMKQIGEIAPQRI-PSLGVQGVMHL
       .       .: :  ....:   ..  :: .  . .......:  :... : . :  ..::
XP_005 LPPKPPPPLQPLLRGGQGLEAALSCPRFLRYPRQHLISSLAEARPEELTPHVMVLLAQHL
           160       170       180       190       200       210   

        400       410       420       430       440       450      
pF1KSD TLYCSALRFLNEGVMNAVAASLPPRVAHCRSKDVAKILWSFGTLNYKPPNAEEFYSSLIS
       . .    :. .  ...:.:  :  . ..  :: : :..  :: ::: : . ..:.  :  
XP_005 ARH----RLREPQLLEAIAHFLVVQETQLSSKVVQKLVLPFGRLNYLPLE-QQFMPCLER
               220       230       240       250        260        

        460       470       480       490       500       510      
pF1KSD EIHRKMPEFNQYPEHLPTCLLGLAFLEYFPVELIDFALSPGFVRLAQERTKFDLLKE-LY
        . :   : .  :    . :..:  :. .: . . :..::::.   .   .  .... : 
XP_005 ILAR---EAGVAPLATVNILMSLCQLRCLPFRALHFVFSPGFINYISGTPHALIVRRYLS
      270          280       290       300       310       320     

         520       530       540       550       560       570     
pF1KSD TLDGTVGIECPDYRGNRLSTHLQQEGSELLWYLAEKDMNSKPEFLETVFLLETMLGGPQY
        :: .: .: : ::: ::  . :                                     
XP_005 LLDTAVELELPGYRGPRLPRRQQVPIFPQPLITDRARCKYSHKDIVAEGLRQLLGEEKYR
         330       340       350       360       370       380     

>>XP_005249990 (OMIM: 606965) PREDICTED: fas-activated s  (515 aa)
 initn: 144 init1:  64 opt: 180  Z-score: 213.1  bits: 49.6 E(85289): 4e-05
Smith-Waterman score: 180; 24.2% identity (53.2% similar) in 293 aa overlap (260-538:66-348)

     230       240       250       260       270       280         
pF1KSD TKCCHQVWEMNMDQLLLVADLWRYLGRKVPRFLNIFSSYLNLHWKDLSLSQLVHLIYVIG
                                     :.:.   : .  :  ...: .: .:.    
XP_005 DRPVGGGPSAGPVQGLQRLLEQAKSPGELLRWLGQNPSKVRAHHYSVALRRLGQLLGSRP
          40        50        60        70        80        90     

     290       300       310       320            330              
pF1KSD ENRQVSQDLMQKLESLILKYIDLINLEEVGTICLGF-----FKSSTNL-----SEFVMRK
       .   : :  .: : .::..    .... .  .:: .     : :.  :     .:  .: 
XP_005 RPPPVEQVTLQDLSQLIIRNCPSFDIHTIH-VCLHLAVLLGFPSDGPLVCALEQERRLR-
         100       110       120        130       140       150    

     340       350         360       370       380        390      
pF1KSD IGDLACANIQHL--SSRSLVNIVKMFRFTHVDHINFMKQIGEIAPQRI-PSLGVQGVMHL
       .       .: :  ....:   ..  :: .  . .......:  :... : . :  ..::
XP_005 LPPKPPPPLQPLLRGGQGLEAALSCPRFLRYPRQHLISSLAEARPEELTPHVMVLLAQHL
           160       170       180       190       200       210   

        400       410       420       430       440       450      
pF1KSD TLYCSALRFLNEGVMNAVAASLPPRVAHCRSKDVAKILWSFGTLNYKPPNAEEFYSSLIS
       . .    :. .  ...:.:  :  . ..  :: : :..  :: ::: : . ..:.  :  
XP_005 ARH----RLREPQLLEAIAHFLVVQETQLSSKVVQKLVLPFGRLNYLPLE-QQFMPCLER
               220       230       240       250        260        

        460       470       480       490       500       510      
pF1KSD EIHRKMPEFNQYPEHLPTCLLGLAFLEYFPVELIDFALSPGFVRLAQERTKFDLLKE-LY
        . :   : .  :    . :..:  :. .: . . :..::::.   .   .  .... : 
XP_005 ILAR---EAGVAPLATVNILMSLCQLRCLPFRALHFVFSPGFINYISGTPHALIVRRYLS
      270          280       290       300       310       320     

         520       530       540       550       560       570     
pF1KSD TLDGTVGIECPDYRGNRLSTHLQQEGSELLWYLAEKDMNSKPEFLETVFLLETMLGGPQY
        :: .: .: : ::: ::  . :                                     
XP_005 LLDTAVELELPGYRGPRLPRRQQVPIFPQPLITDRARCKYSHKDIVAEGLRQLLGEEKYR
         330       340       350       360       370       380     

>>NP_006703 (OMIM: 606965) fas-activated serine/threonin  (549 aa)
 initn: 144 init1:  64 opt: 180  Z-score: 212.7  bits: 49.6 E(85289): 4.2e-05
Smith-Waterman score: 180; 24.2% identity (53.2% similar) in 293 aa overlap (260-538:100-382)

     230       240       250       260       270       280         
pF1KSD TKCCHQVWEMNMDQLLLVADLWRYLGRKVPRFLNIFSSYLNLHWKDLSLSQLVHLIYVIG
                                     :.:.   : .  :  ...: .: .:.    
NP_006 DRPVGGGPSAGPVQGLQRLLEQAKSPGELLRWLGQNPSKVRAHHYSVALRRLGQLLGSRP
      70        80        90       100       110       120         

     290       300       310       320            330              
pF1KSD ENRQVSQDLMQKLESLILKYIDLINLEEVGTICLGF-----FKSSTNL-----SEFVMRK
       .   : :  .: : .::..    .... .  .:: .     : :.  :     .:  .: 
NP_006 RPPPVEQVTLQDLSQLIIRNCPSFDIHTIH-VCLHLAVLLGFPSDGPLVCALEQERRLR-
     130       140       150        160       170       180        

     340       350         360       370       380        390      
pF1KSD IGDLACANIQHL--SSRSLVNIVKMFRFTHVDHINFMKQIGEIAPQRI-PSLGVQGVMHL
       .       .: :  ....:   ..  :: .  . .......:  :... : . :  ..::
NP_006 LPPKPPPPLQPLLRGGQGLEAALSCPRFLRYPRQHLISSLAEARPEELTPHVMVLLAQHL
       190       200       210       220       230       240       

        400       410       420       430       440       450      
pF1KSD TLYCSALRFLNEGVMNAVAASLPPRVAHCRSKDVAKILWSFGTLNYKPPNAEEFYSSLIS
       . .    :. .  ...:.:  :  . ..  :: : :..  :: ::: : . ..:.  :  
NP_006 ARH----RLREPQLLEAIAHFLVVQETQLSSKVVQKLVLPFGRLNYLPLE-QQFMPCLER
       250           260       270       280       290        300  

        460       470       480       490       500       510      
pF1KSD EIHRKMPEFNQYPEHLPTCLLGLAFLEYFPVELIDFALSPGFVRLAQERTKFDLLKE-LY
        . :   : .  :    . :..:  :. .: . . :..::::.   .   .  .... : 
NP_006 ILAR---EAGVAPLATVNILMSLCQLRCLPFRALHFVFSPGFINYISGTPHALIVRRYLS
               310       320       330       340       350         

         520       530       540       550       560       570     
pF1KSD TLDGTVGIECPDYRGNRLSTHLQQEGSELLWYLAEKDMNSKPEFLETVFLLETMLGGPQY
        :: .: .: : ::: ::  . :                                     
NP_006 LLDTAVELELPGYRGPRLPRRQQVPIFPQPLITDRARCKYSHKDIVAEGLRQLLGEEKYR
     360       370       380       390       400       410         

>>XP_016867194 (OMIM: 606965) PREDICTED: fas-activated s  (353 aa)
 initn: 150 init1:  64 opt: 177  Z-score: 211.9  bits: 48.8 E(85289): 4.6e-05
Smith-Waterman score: 177; 27.1% identity (57.1% similar) in 177 aa overlap (364-538:73-241)

           340       350       360       370       380        390  
pF1KSD EFVMRKIGDLACANIQHLSSRSLVNIVKMFRFTHVDHINFMKQIGEIAPQRI-PSLGVQG
                                     :: .  . .......:  :... : . :  
XP_016 RRLRLPPKPPPPLQPLLRGGQGLEAALSCPRFLRYPRQHLISSLAEARPEELTPHVMVLL
             50        60        70        80        90       100  

            400       410       420       430       440       450  
pF1KSD VMHLTLYCSALRFLNEGVMNAVAASLPPRVAHCRSKDVAKILWSFGTLNYKPPNAEEFYS
       ..::. .    :. .  ...:.:  :  . ..  :: : :..  :: ::: : . ..:. 
XP_016 AQHLARH----RLREPQLLEAIAHFLVVQETQLSSKVVQKLVLPFGRLNYLPLE-QQFMP
                110       120       130       140       150        

            460       470       480       490       500       510  
pF1KSD SLISEIHRKMPEFNQYPEHLPTCLLGLAFLEYFPVELIDFALSPGFVRLAQERTKFDLLK
        :   . :   : .  :    . :..:  :. .: . . :..::::.   .   .  ...
XP_016 CLERILAR---EAGVAPLATVNILMSLCQLRCLPFRALHFVFSPGFINYISGTPHALIVR
       160          170       180       190       200       210    

             520       530       540       550       560       570 
pF1KSD E-LYTLDGTVGIECPDYRGNRLSTHLQQEGSELLWYLAEKDMNSKPEFLETVFLLETMLG
       . :  :: .: .: : ::: ::  . :                                 
XP_016 RYLSLLDTAVELELPGYRGPRLPRRQQVPIFPQPLITDRARCKYSHKDIVAEGLRQLLGE
          220       230       240       250       260       270    

>>NP_148936 (OMIM: 606965) fas-activated serine/threonin  (408 aa)
 initn: 150 init1:  64 opt: 177  Z-score: 211.0  bits: 48.9 E(85289): 5.2e-05
Smith-Waterman score: 177; 27.1% identity (57.1% similar) in 177 aa overlap (364-538:73-241)

           340       350       360       370       380        390  
pF1KSD EFVMRKIGDLACANIQHLSSRSLVNIVKMFRFTHVDHINFMKQIGEIAPQRI-PSLGVQG
                                     :: .  . .......:  :... : . :  
NP_148 RRLRLPPKPPPPLQPLLRGGQGLEAALSCPRFLRYPRQHLISSLAEARPEELTPHVMVLL
             50        60        70        80        90       100  

            400       410       420       430       440       450  
pF1KSD VMHLTLYCSALRFLNEGVMNAVAASLPPRVAHCRSKDVAKILWSFGTLNYKPPNAEEFYS
       ..::. .    :. .  ...:.:  :  . ..  :: : :..  :: ::: : . ..:. 
NP_148 AQHLARH----RLREPQLLEAIAHFLVVQETQLSSKVVQKLVLPFGRLNYLPLE-QQFMP
                110       120       130       140       150        

            460       470       480       490       500       510  
pF1KSD SLISEIHRKMPEFNQYPEHLPTCLLGLAFLEYFPVELIDFALSPGFVRLAQERTKFDLLK
        :   . :   : .  :    . :..:  :. .: . . :..::::.   .   .  ...
NP_148 CLERILAR---EAGVAPLATVNILMSLCQLRCLPFRALHFVFSPGFINYISGTPHALIVR
       160          170       180       190       200       210    

             520       530       540       550       560       570 
pF1KSD E-LYTLDGTVGIECPDYRGNRLSTHLQQEGSELLWYLAEKDMNSKPEFLETVFLLETMLG
       . :  :: .: .: : ::: ::  . :                                 
NP_148 RYLSLLDTAVELELPGYRGPRLPRRQQVPIFPQPLITDRARCKYSHKDIVAEGLRQLLGE
          220       230       240       250       260       270    

>>XP_011514065 (OMIM: 606965) PREDICTED: fas-activated s  (381 aa)
 initn: 150 init1:  64 opt: 162  Z-score: 193.6  bits: 45.5 E(85289): 0.00048
Smith-Waterman score: 162; 28.4% identity (55.6% similar) in 162 aa overlap (379-538:61-214)

      350       360       370       380        390       400       
pF1KSD QHLSSRSLVNIVKMFRFTHVDHINFMKQIGEIAPQRI-PSLGVQGVMHLTLYCSALRFLN
                                     :  :... : . :  ..::. .    :. .
XP_011 SDGPLVCALEQERRLRLPPKPPPPLQPLLREARPEELTPHVMVLLAQHLARH----RLRE
               40        50        60        70        80          

       410       420       430       440       450       460       
pF1KSD EGVMNAVAASLPPRVAHCRSKDVAKILWSFGTLNYKPPNAEEFYSSLISEIHRKMPEFNQ
         ...:.:  :  . ..  :: : :..  :: ::: : . ..:.  :   . :   : . 
XP_011 PQLLEAIAHFLVVQETQLSSKVVQKLVLPFGRLNYLPLE-QQFMPCLERILAR---EAGV
         90       100       110       120        130          140  

       470       480       490       500       510        520      
pF1KSD YPEHLPTCLLGLAFLEYFPVELIDFALSPGFVRLAQERTKFDLLKE-LYTLDGTVGIECP
        :    . :..:  :. .: . . :..::::.   .   .  .... :  :: .: .: :
XP_011 APLATVNILMSLCQLRCLPFRALHFVFSPGFINYISGTPHALIVRRYLSLLDTAVELELP
            150       160       170       180       190       200  

        530       540       550       560       570       580      
pF1KSD DYRGNRLSTHLQQEGSELLWYLAEKDMNSKPEFLETVFLLETMLGGPQYVKHHMILPHTR
        ::: ::  . :                                                
XP_011 GYRGPRLPRRQQVPIFPQPLITDRARCKYSHKDIVAEGLRQLLGEEKYRQDLTVPPGYCT
            210       220       230       240       250       260  

>>XP_016867193 (OMIM: 606965) PREDICTED: fas-activated s  (488 aa)
 initn: 185 init1:  64 opt: 162  Z-score: 192.0  bits: 45.6 E(85289): 0.00059
Smith-Waterman score: 169; 24.6% identity (51.2% similar) in 281 aa overlap (260-538:66-321)

     230       240       250       260       270       280         
pF1KSD TKCCHQVWEMNMDQLLLVADLWRYLGRKVPRFLNIFSSYLNLHWKDLSLSQLVHLIYVIG
                                     :.:.   : .  :  ...: .: .:.    
XP_016 DRPVGGGPSAGPVQGLQRLLEQAKSPGELLRWLGQNPSKVRAHHYSVALRRLGQLLGSRP
          40        50        60        70        80        90     

     290       300       310       320       330       340         
pF1KSD ENRQVSQDLMQKLESLILKYIDLINLEEVGTICLGFFKSSTNLSEFVMRKIGDLACANIQ
       .   : :  .: : .::..    .... .  .:: .    . :  :   . : :.::  :
XP_016 RPPPVEQVTLQDLSQLIIRNCPSFDIHTIH-VCLHL----AVLLGF--PSDGPLVCALEQ
         100       110       120        130             140        

     350       360       370       380        390       400        
pF1KSD HLSSRSLVNIVKMFRFTHVDHINFMKQIGEIAPQRI-PSLGVQGVMHLTLYCSALRFLNE
       .          . .:.       ..  . :  :... : . :  ..::. .    :. . 
XP_016 E----------RRLRLPPKPPPPLQPLLREARPEELTPHVMVLLAQHLARH----RLREP
                150       160       170       180           190    

      410       420       430       440       450       460        
pF1KSD GVMNAVAASLPPRVAHCRSKDVAKILWSFGTLNYKPPNAEEFYSSLISEIHRKMPEFNQY
        ...:.:  :  . ..  :: : :..  :: ::: : . ..:.  :   . :   : .  
XP_016 QLLEAIAHFLVVQETQLSSKVVQKLVLPFGRLNYLPLE-QQFMPCLERILAR---EAGVA
          200       210       220       230        240          250

      470       480       490       500       510        520       
pF1KSD PEHLPTCLLGLAFLEYFPVELIDFALSPGFVRLAQERTKFDLLKE-LYTLDGTVGIECPD
       :    . :..:  :. .: . . :..::::.   .   .  .... :  :: .: .: : 
XP_016 PLATVNILMSLCQLRCLPFRALHFVFSPGFINYISGTPHALIVRRYLSLLDTAVELELPG
              260       270       280       290       300       310

       530       540       550       560       570       580       
pF1KSD YRGNRLSTHLQQEGSELLWYLAEKDMNSKPEFLETVFLLETMLGGPQYVKHHMILPHTRS
       ::: ::  . :                                                 
XP_016 YRGPRLPRRQQVPIFPQPLITDRARCKYSHKDIVAEGLRQLLGEEKYRQDLTVPPGYCTD
              320       330       340       350       360       370




764 residues in 1 query   sequences
60827320 residues in 85289 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Thu Nov  3 07:21:42 2016 done: Thu Nov  3 07:21:44 2016
 Total Scan time: 11.840 Total Display time:  0.070

Function used was FASTA [36.3.4 Apr, 2011]
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