Result of FASTA (omim) for pF1KSDA1427
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KSDA1427, 426 aa
  1>>>pF1KSDA1427 426 - 426 aa - 426 aa
Library: /omim/omim.rfq.tfa
  60827320 residues in 85289 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 6.7579+/-0.000344; mu= 10.9583+/- 0.022
 mean_var=109.5808+/-21.998, 0's: 0 Z-trim(117.9): 167  B-trim: 423 in 1/55
 Lambda= 0.122520
 statistics sampled from 30187 (30375) to 30187 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.713), E-opt: 0.2 (0.356), width:  16
 Scan time:  9.980

The best scores are:                                      opt bits E(85289)
NP_065877 (OMIM: 607716) synaptotagmin-13 isoform  ( 426) 2844 513.3 4.6e-145
NP_001234916 (OMIM: 607716) synaptotagmin-13 isofo ( 282) 1881 343.0 5.7e-94
XP_006723404 (OMIM: 600782) PREDICTED: synaptotagm ( 383)  515 101.6 3.6e-21
NP_001278830 (OMIM: 185605) synaptotagmin-1 isofor ( 419)  510 100.8 7.1e-21
XP_005269170 (OMIM: 185605) PREDICTED: synaptotagm ( 419)  510 100.8 7.1e-21
XP_006719639 (OMIM: 185605) PREDICTED: synaptotagm ( 419)  510 100.8 7.1e-21
NP_001129277 (OMIM: 185605) synaptotagmin-1 isofor ( 422)  510 100.8 7.1e-21
NP_005630 (OMIM: 185605) synaptotagmin-1 isoform 1 ( 422)  510 100.8 7.1e-21
NP_001129278 (OMIM: 185605) synaptotagmin-1 isofor ( 422)  510 100.8 7.1e-21
XP_016875398 (OMIM: 185605) PREDICTED: synaptotagm ( 422)  510 100.8 7.1e-21
XP_011537012 (OMIM: 185605) PREDICTED: synaptotagm ( 422)  510 100.8 7.1e-21
NP_001284703 (OMIM: 600782) synaptotagmin-5 isofor ( 382)  504 99.7 1.4e-20
XP_016882664 (OMIM: 600782) PREDICTED: synaptotagm ( 386)  497 98.4 3.2e-20
XP_016882665 (OMIM: 600782) PREDICTED: synaptotagm ( 386)  497 98.4 3.2e-20
NP_003171 (OMIM: 600782) synaptotagmin-5 isoform 1 ( 386)  497 98.4 3.2e-20
XP_006723402 (OMIM: 600782) PREDICTED: synaptotagm ( 386)  497 98.4 3.2e-20
NP_796376 (OMIM: 600104,616040) synaptotagmin-2 [H ( 419)  496 98.3 3.9e-20
NP_001129976 (OMIM: 600104,616040) synaptotagmin-2 ( 419)  496 98.3 3.9e-20
XP_016855802 (OMIM: 600104,616040) PREDICTED: syna ( 419)  496 98.3 3.9e-20
XP_016855800 (OMIM: 600104,616040) PREDICTED: syna ( 422)  496 98.3 3.9e-20
XP_016855801 (OMIM: 600104,616040) PREDICTED: syna ( 422)  496 98.3 3.9e-20
XP_011507494 (OMIM: 600104,616040) PREDICTED: syna ( 422)  496 98.3 3.9e-20
XP_016855799 (OMIM: 600104,616040) PREDICTED: syna ( 476)  496 98.3 4.4e-20
XP_016855798 (OMIM: 600104,616040) PREDICTED: syna ( 479)  496 98.3 4.4e-20
NP_001257734 (OMIM: 607718) synaptotagmin-6 [Homo  ( 425)  495 98.1 4.5e-20
NP_995320 (OMIM: 607718) synaptotagmin-6 [Homo sap ( 425)  495 98.1 4.5e-20
XP_016855860 (OMIM: 607718) PREDICTED: synaptotagm ( 443)  495 98.1 4.6e-20
XP_006723403 (OMIM: 600782) PREDICTED: synaptotagm ( 385)  486 96.5 1.2e-19
NP_783860 (OMIM: 613528) synaptotagmin-9 [Homo sap ( 491)  475 94.6 5.9e-19
XP_011518206 (OMIM: 613528) PREDICTED: synaptotagm ( 492)  475 94.6 5.9e-19
XP_011518204 (OMIM: 613528) PREDICTED: synaptotagm ( 535)  475 94.6 6.3e-19
XP_011518203 (OMIM: 613528) PREDICTED: synaptotagm ( 564)  475 94.7 6.6e-19
XP_011518202 (OMIM: 613528) PREDICTED: synaptotagm ( 567)  475 94.7 6.6e-19
XP_011525693 (OMIM: 600327) PREDICTED: synaptotagm ( 590)  434 87.4   1e-16
XP_011525692 (OMIM: 600327) PREDICTED: synaptotagm ( 590)  434 87.4   1e-16
NP_115674 (OMIM: 600327) synaptotagmin-3 [Homo sap ( 590)  434 87.4   1e-16
NP_001153800 (OMIM: 600327) synaptotagmin-3 [Homo  ( 590)  434 87.4   1e-16
NP_001153801 (OMIM: 600327) synaptotagmin-3 [Homo  ( 590)  434 87.4   1e-16
NP_004191 (OMIM: 604146) synaptotagmin-7 isoform 2 ( 403)  431 86.8 1.1e-16
XP_011543645 (OMIM: 604146) PREDICTED: synaptotagm ( 409)  431 86.8 1.1e-16
NP_001287702 (OMIM: 604146) synaptotagmin-7 isofor ( 447)  431 86.8 1.2e-16
XP_005274444 (OMIM: 604146) PREDICTED: synaptotagm ( 449)  431 86.8 1.2e-16
XP_011543643 (OMIM: 604146) PREDICTED: synaptotagm ( 453)  431 86.8 1.2e-16
NP_001238994 (OMIM: 604146) synaptotagmin-7 isofor ( 478)  431 86.8 1.3e-16
XP_011543642 (OMIM: 604146) PREDICTED: synaptotagm ( 484)  431 86.8 1.3e-16
XP_011543641 (OMIM: 604146) PREDICTED: synaptotagm ( 528)  431 86.9 1.4e-16
XP_005274442 (OMIM: 604146) PREDICTED: synaptotagm ( 611)  431 86.9 1.5e-16
XP_011543640 (OMIM: 604146) PREDICTED: synaptotagm ( 617)  431 86.9 1.6e-16
XP_005274441 (OMIM: 604146) PREDICTED: synaptotagm ( 642)  431 86.9 1.6e-16
XP_011543639 (OMIM: 604146) PREDICTED: synaptotagm ( 648)  431 86.9 1.6e-16


>>NP_065877 (OMIM: 607716) synaptotagmin-13 isoform 1 [H  (426 aa)
 initn: 2844 init1: 2844 opt: 2844  Z-score: 2725.3  bits: 513.3 E(85289): 4.6e-145
Smith-Waterman score: 2844; 100.0% identity (100.0% similar) in 426 aa overlap (1-426:1-426)

               10        20        30        40        50        60
pF1KSD MVLSVPVIALGATLGTATSILALCGVTCLCRHMHPKKGLLPRDQDPDLEKAKPSLLGSAQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_065 MVLSVPVIALGATLGTATSILALCGVTCLCRHMHPKKGLLPRDQDPDLEKAKPSLLGSAQ
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KSD QFNVKKSTEPVQPRALLKFPDIYGPRPAVTAPEVINYADYSLRSTEEPTAPASPQPPNDS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_065 QFNVKKSTEPVQPRALLKFPDIYGPRPAVTAPEVINYADYSLRSTEEPTAPASPQPPNDS
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KSD RLKRQVTEELFILPQNGVVEDVCVMETWNPEKAASWNQAPKLHYCLDYDCQKAELFVTRL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_065 RLKRQVTEELFILPQNGVVEDVCVMETWNPEKAASWNQAPKLHYCLDYDCQKAELFVTRL
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KSD EAVTSNHDGGCDCYVQGSVANRTGSVEAQTALKKRQLHTTWEEGLVLPLAEEELPTATLT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_065 EAVTSNHDGGCDCYVQGSVANRTGSVEAQTALKKRQLHTTWEEGLVLPLAEEELPTATLT
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KSD LTLRTCDRFSRHSVAGELRLGLDGTSVPLGAAQWGELKTSAKEPSAGAGEVLLSISYLPA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_065 LTLRTCDRFSRHSVAGELRLGLDGTSVPLGAAQWGELKTSAKEPSAGAGEVLLSISYLPA
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KSD ANRLLVVLIKAKNLHSNQSKELLGKDVSVKVTLKHQARKLKKKQTKRAKHKINPVWNEMI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_065 ANRLLVVLIKAKNLHSNQSKELLGKDVSVKVTLKHQARKLKKKQTKRAKHKINPVWNEMI
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KSD MFELPDDLLQASSVELEVLGQDDSGQSCALGHCSLGLHTSGSERSHWEEMLKNPRRQIAM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_065 MFELPDDLLQASSVELEVLGQDDSGQSCALGHCSLGLHTSGSERSHWEEMLKNPRRQIAM
              370       380       390       400       410       420

             
pF1KSD WHQLHL
       ::::::
NP_065 WHQLHL
             

>>NP_001234916 (OMIM: 607716) synaptotagmin-13 isoform 2  (282 aa)
 initn: 1881 init1: 1881 opt: 1881  Z-score: 1808.0  bits: 343.0 E(85289): 5.7e-94
Smith-Waterman score: 1881; 100.0% identity (100.0% similar) in 282 aa overlap (145-426:1-282)

          120       130       140       150       160       170    
pF1KSD QPPNDSRLKRQVTEELFILPQNGVVEDVCVMETWNPEKAASWNQAPKLHYCLDYDCQKAE
                                     ::::::::::::::::::::::::::::::
NP_001                               METWNPEKAASWNQAPKLHYCLDYDCQKAE
                                             10        20        30

          180       190       200       210       220       230    
pF1KSD LFVTRLEAVTSNHDGGCDCYVQGSVANRTGSVEAQTALKKRQLHTTWEEGLVLPLAEEEL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LFVTRLEAVTSNHDGGCDCYVQGSVANRTGSVEAQTALKKRQLHTTWEEGLVLPLAEEEL
               40        50        60        70        80        90

          240       250       260       270       280       290    
pF1KSD PTATLTLTLRTCDRFSRHSVAGELRLGLDGTSVPLGAAQWGELKTSAKEPSAGAGEVLLS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PTATLTLTLRTCDRFSRHSVAGELRLGLDGTSVPLGAAQWGELKTSAKEPSAGAGEVLLS
              100       110       120       130       140       150

          300       310       320       330       340       350    
pF1KSD ISYLPAANRLLVVLIKAKNLHSNQSKELLGKDVSVKVTLKHQARKLKKKQTKRAKHKINP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ISYLPAANRLLVVLIKAKNLHSNQSKELLGKDVSVKVTLKHQARKLKKKQTKRAKHKINP
              160       170       180       190       200       210

          360       370       380       390       400       410    
pF1KSD VWNEMIMFELPDDLLQASSVELEVLGQDDSGQSCALGHCSLGLHTSGSERSHWEEMLKNP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VWNEMIMFELPDDLLQASSVELEVLGQDDSGQSCALGHCSLGLHTSGSERSHWEEMLKNP
              220       230       240       250       260       270

          420      
pF1KSD RRQIAMWHQLHL
       ::::::::::::
NP_001 RRQIAMWHQLHL
              280  

>>XP_006723404 (OMIM: 600782) PREDICTED: synaptotagmin-5  (383 aa)
 initn: 502 init1: 273 opt: 515  Z-score: 501.2  bits: 101.6 E(85289): 3.6e-21
Smith-Waterman score: 515; 32.3% identity (61.3% similar) in 328 aa overlap (104-424:50-371)

            80        90       100       110       120       130   
pF1KSD RALLKFPDIYGPRPAVTAPEVINYADYSLRSTEEPTAPASPQPPNDSRLKRQVTEELFIL
                                     :   :    :::: .  :  :  :      
XP_006 SWSSLLCVGLKGRLGWEWGTRVLECLCRKDSRTPPPCSRSPQPRGLHRPTRLPTPVASAT
      20        30        40        50        60        70         

            140       150       160       170       180            
pF1KSD PQ-NGVVEDVCVMETWNPEKAASWNQAPKLHYCLDYDCQKAELFVTRLEAV---TSNHDG
        : .  ::..    .   ...:. ..  .:.: :::: :...:.:  :.:.   . .  :
XP_006 AQVQPEVEELEPAPSGPGQQVADKHELGRLQYSLDYDFQSGQLLVGILQAMGLAALDLGG
      80        90       100       110       120       130         

     190        200       210       220       230       240        
pF1KSD GCDCYVQGSV-ANRTGSVEAQTALKKRQLHTTWEEGLVLPLAEEELPTATLTLTLRTCDR
       . : ::.  .  ..    :  : .... :.  . : ... .   ::   .:....   ::
XP_006 SSDPYVRVYLLPDKRRRYE--TKVHRQTLNPHFGETFAFKVPYVELGGRVLVMAVYDFDR
     140       150         160       170       180       190       

      250       260       270         280       290       300      
pF1KSD FSRHSVAGELRLGLDGTSVPLG--AAQWGELKTSAKEPSAGAGEVLLSISYLPAANRLLV
       :::... ::.:. .  .:: ::  .  : ::... .: .   :.. .:. :.:.:..: :
XP_006 FSRNDAIGEVRVPM--SSVDLGRPVQAWRELQAAPREEQEKLGDICFSLRYVPTAGKLTV
       200       210         220       230       240       250     

        310       320       330       340       350       360      
pF1KSD VLIKAKNLHSNQSKELLGKDVSVKVTLKHQARKLKKKQTKRAKHKINPVWNEMIMFELPD
       ....::::.. .   :  .:  ::: : . ..:..::.:   :. .:: .:: . ::.: 
XP_006 IVLEAKNLKKMDVGGL--SDPYVKVHLLQGGKKVRKKKTTIKKNTLNPYYNEAFSFEVPC
         260       270         280       290       300       310   

        370       380       390       400       410       420      
pF1KSD DLLQASSVELEVLGQDDSGQSCALGHCSLGLHTSGSERSHWEEMLKNPRRQIAMWHQLHL
       : .:  .::: ::  :  :.. :.:. ..:  ..:.   :: .:: :::: ::.::.:  
XP_006 DQVQKVQVELTVLDYDKLGKNEAIGRVAVGAAAGGAGLRHWADMLANPRRPIAQWHSLRP
           320       330       340       350       360       370   

XP_006 PDRVRLLPAP
           380   

>>NP_001278830 (OMIM: 185605) synaptotagmin-1 isoform 2   (419 aa)
 initn: 562 init1: 272 opt: 510  Z-score: 495.8  bits: 100.8 E(85289): 7.1e-21
Smith-Waterman score: 510; 32.6% identity (66.3% similar) in 270 aa overlap (161-426:142-407)

              140       150       160       170       180          
pF1KSD FILPQNGVVEDVCVMETWNPEKAASWNQAPKLHYCLDYDCQKAELFVTRLEAV---TSNH
                                     ::.: :::: :. .:.:  ..:.   . . 
NP_001 KTMKDQDDDAETGLTDGEEKEEPKEEEKLGKLQYSLDYDFQNNQLLVGIIQAAELPALDM
             120       130       140       150       160       170 

       190        200       210       220       230       240      
pF1KSD DGGCDCYVQGSV-ANRTGSVEAQTALKKRQLHTTWEEGLVLPLAEEELPTATLTLTLRTC
        :  : ::.  .  ..  . :  : .... :. ...: ... .   ::   ::....   
NP_001 GGTSDPYVKVFLLPDKKKKFE--TKVHRKTLNPVFNEQFTFKVPYSELGGKTLVMAVYDF
             180       190         200       210       220         

        250       260       270       280       290       300      
pF1KSD DRFSRHSVAGELRLGLDGTSVPLGAAQWGELKTSAKEPSAGAGEVLLSISYLPAANRLLV
       ::::.:.. ::... .. ..    . .: .:... :: .   :.. .:. :.:.:..: :
NP_001 DRFSKHDIIGEFKVPMNTVDFGHVTEEWRDLQSAEKEEQEKLGDICFSLRYVPTAGKLTV
     230       240       250       260       270       280         

        310       320       330       340       350       360      
pF1KSD VLIKAKNLHSNQSKELLGKDVSVKVTLKHQARKLKKKQTKRAKHKINPVWNEMIMFELPD
       :...::::.. .   :  .:  ::. : .....::::.:   :. .:: .:: . ::.: 
NP_001 VILEAKNLKKMDVGGL--SDPYVKIHLMQNGKRLKKKKTTIKKNTLNPYYNESFSFEVPF
     290       300         310       320       330       340       

        370       380       390       400       410       420      
pF1KSD DLLQASSVELEVLGQDDSGQSCALGHCSLGLHTSGSERSHWEEMLKNPRRQIAMWHQLHL
       . .:  .: . ::  :  :.. :.:.  .: ...:.:  :: .:: :::: ::.:: :..
NP_001 EQIQKVQVVVTVLDYDKIGKNDAIGKVFVGYNSTGAELRHWSDMLANPRRPIAQWHTLQV
       350       360       370       380       390       400       

NP_001 EEEVDAMLAVKK
       410         

>>XP_005269170 (OMIM: 185605) PREDICTED: synaptotagmin-1  (419 aa)
 initn: 562 init1: 272 opt: 510  Z-score: 495.8  bits: 100.8 E(85289): 7.1e-21
Smith-Waterman score: 510; 32.6% identity (66.3% similar) in 270 aa overlap (161-426:142-407)

              140       150       160       170       180          
pF1KSD FILPQNGVVEDVCVMETWNPEKAASWNQAPKLHYCLDYDCQKAELFVTRLEAV---TSNH
                                     ::.: :::: :. .:.:  ..:.   . . 
XP_005 KTMKDQDDDAETGLTDGEEKEEPKEEEKLGKLQYSLDYDFQNNQLLVGIIQAAELPALDM
             120       130       140       150       160       170 

       190        200       210       220       230       240      
pF1KSD DGGCDCYVQGSV-ANRTGSVEAQTALKKRQLHTTWEEGLVLPLAEEELPTATLTLTLRTC
        :  : ::.  .  ..  . :  : .... :. ...: ... .   ::   ::....   
XP_005 GGTSDPYVKVFLLPDKKKKFE--TKVHRKTLNPVFNEQFTFKVPYSELGGKTLVMAVYDF
             180       190         200       210       220         

        250       260       270       280       290       300      
pF1KSD DRFSRHSVAGELRLGLDGTSVPLGAAQWGELKTSAKEPSAGAGEVLLSISYLPAANRLLV
       ::::.:.. ::... .. ..    . .: .:... :: .   :.. .:. :.:.:..: :
XP_005 DRFSKHDIIGEFKVPMNTVDFGHVTEEWRDLQSAEKEEQEKLGDICFSLRYVPTAGKLTV
     230       240       250       260       270       280         

        310       320       330       340       350       360      
pF1KSD VLIKAKNLHSNQSKELLGKDVSVKVTLKHQARKLKKKQTKRAKHKINPVWNEMIMFELPD
       :...::::.. .   :  .:  ::. : .....::::.:   :. .:: .:: . ::.: 
XP_005 VILEAKNLKKMDVGGL--SDPYVKIHLMQNGKRLKKKKTTIKKNTLNPYYNESFSFEVPF
     290       300         310       320       330       340       

        370       380       390       400       410       420      
pF1KSD DLLQASSVELEVLGQDDSGQSCALGHCSLGLHTSGSERSHWEEMLKNPRRQIAMWHQLHL
       . .:  .: . ::  :  :.. :.:.  .: ...:.:  :: .:: :::: ::.:: :..
XP_005 EQIQKVQVVVTVLDYDKIGKNDAIGKVFVGYNSTGAELRHWSDMLANPRRPIAQWHTLQV
       350       360       370       380       390       400       

XP_005 EEEVDAMLAVKK
       410         

>>XP_006719639 (OMIM: 185605) PREDICTED: synaptotagmin-1  (419 aa)
 initn: 562 init1: 272 opt: 510  Z-score: 495.8  bits: 100.8 E(85289): 7.1e-21
Smith-Waterman score: 510; 32.6% identity (66.3% similar) in 270 aa overlap (161-426:142-407)

              140       150       160       170       180          
pF1KSD FILPQNGVVEDVCVMETWNPEKAASWNQAPKLHYCLDYDCQKAELFVTRLEAV---TSNH
                                     ::.: :::: :. .:.:  ..:.   . . 
XP_006 KTMKDQDDDAETGLTDGEEKEEPKEEEKLGKLQYSLDYDFQNNQLLVGIIQAAELPALDM
             120       130       140       150       160       170 

       190        200       210       220       230       240      
pF1KSD DGGCDCYVQGSV-ANRTGSVEAQTALKKRQLHTTWEEGLVLPLAEEELPTATLTLTLRTC
        :  : ::.  .  ..  . :  : .... :. ...: ... .   ::   ::....   
XP_006 GGTSDPYVKVFLLPDKKKKFE--TKVHRKTLNPVFNEQFTFKVPYSELGGKTLVMAVYDF
             180       190         200       210       220         

        250       260       270       280       290       300      
pF1KSD DRFSRHSVAGELRLGLDGTSVPLGAAQWGELKTSAKEPSAGAGEVLLSISYLPAANRLLV
       ::::.:.. ::... .. ..    . .: .:... :: .   :.. .:. :.:.:..: :
XP_006 DRFSKHDIIGEFKVPMNTVDFGHVTEEWRDLQSAEKEEQEKLGDICFSLRYVPTAGKLTV
     230       240       250       260       270       280         

        310       320       330       340       350       360      
pF1KSD VLIKAKNLHSNQSKELLGKDVSVKVTLKHQARKLKKKQTKRAKHKINPVWNEMIMFELPD
       :...::::.. .   :  .:  ::. : .....::::.:   :. .:: .:: . ::.: 
XP_006 VILEAKNLKKMDVGGL--SDPYVKIHLMQNGKRLKKKKTTIKKNTLNPYYNESFSFEVPF
     290       300         310       320       330       340       

        370       380       390       400       410       420      
pF1KSD DLLQASSVELEVLGQDDSGQSCALGHCSLGLHTSGSERSHWEEMLKNPRRQIAMWHQLHL
       . .:  .: . ::  :  :.. :.:.  .: ...:.:  :: .:: :::: ::.:: :..
XP_006 EQIQKVQVVVTVLDYDKIGKNDAIGKVFVGYNSTGAELRHWSDMLANPRRPIAQWHTLQV
       350       360       370       380       390       400       

XP_006 EEEVDAMLAVKK
       410         

>>NP_001129277 (OMIM: 185605) synaptotagmin-1 isoform 1   (422 aa)
 initn: 562 init1: 272 opt: 510  Z-score: 495.8  bits: 100.8 E(85289): 7.1e-21
Smith-Waterman score: 510; 32.6% identity (66.3% similar) in 270 aa overlap (161-426:145-410)

              140       150       160       170       180          
pF1KSD FILPQNGVVEDVCVMETWNPEKAASWNQAPKLHYCLDYDCQKAELFVTRLEAV---TSNH
                                     ::.: :::: :. .:.:  ..:.   . . 
NP_001 KDQALKDDDAETGLTDGEEKEEPKEEEKLGKLQYSLDYDFQNNQLLVGIIQAAELPALDM
          120       130       140       150       160       170    

       190        200       210       220       230       240      
pF1KSD DGGCDCYVQGSV-ANRTGSVEAQTALKKRQLHTTWEEGLVLPLAEEELPTATLTLTLRTC
        :  : ::.  .  ..  . :  : .... :. ...: ... .   ::   ::....   
NP_001 GGTSDPYVKVFLLPDKKKKFE--TKVHRKTLNPVFNEQFTFKVPYSELGGKTLVMAVYDF
          180       190         200       210       220       230  

        250       260       270       280       290       300      
pF1KSD DRFSRHSVAGELRLGLDGTSVPLGAAQWGELKTSAKEPSAGAGEVLLSISYLPAANRLLV
       ::::.:.. ::... .. ..    . .: .:... :: .   :.. .:. :.:.:..: :
NP_001 DRFSKHDIIGEFKVPMNTVDFGHVTEEWRDLQSAEKEEQEKLGDICFSLRYVPTAGKLTV
            240       250       260       270       280       290  

        310       320       330       340       350       360      
pF1KSD VLIKAKNLHSNQSKELLGKDVSVKVTLKHQARKLKKKQTKRAKHKINPVWNEMIMFELPD
       :...::::.. .   :  .:  ::. : .....::::.:   :. .:: .:: . ::.: 
NP_001 VILEAKNLKKMDVGGL--SDPYVKIHLMQNGKRLKKKKTTIKKNTLNPYYNESFSFEVPF
            300         310       320       330       340       350

        370       380       390       400       410       420      
pF1KSD DLLQASSVELEVLGQDDSGQSCALGHCSLGLHTSGSERSHWEEMLKNPRRQIAMWHQLHL
       . .:  .: . ::  :  :.. :.:.  .: ...:.:  :: .:: :::: ::.:: :..
NP_001 EQIQKVQVVVTVLDYDKIGKNDAIGKVFVGYNSTGAELRHWSDMLANPRRPIAQWHTLQV
              360       370       380       390       400       410

NP_001 EEEVDAMLAVKK
              420  

>>NP_005630 (OMIM: 185605) synaptotagmin-1 isoform 1 [Ho  (422 aa)
 initn: 562 init1: 272 opt: 510  Z-score: 495.8  bits: 100.8 E(85289): 7.1e-21
Smith-Waterman score: 510; 32.6% identity (66.3% similar) in 270 aa overlap (161-426:145-410)

              140       150       160       170       180          
pF1KSD FILPQNGVVEDVCVMETWNPEKAASWNQAPKLHYCLDYDCQKAELFVTRLEAV---TSNH
                                     ::.: :::: :. .:.:  ..:.   . . 
NP_005 KDQALKDDDAETGLTDGEEKEEPKEEEKLGKLQYSLDYDFQNNQLLVGIIQAAELPALDM
          120       130       140       150       160       170    

       190        200       210       220       230       240      
pF1KSD DGGCDCYVQGSV-ANRTGSVEAQTALKKRQLHTTWEEGLVLPLAEEELPTATLTLTLRTC
        :  : ::.  .  ..  . :  : .... :. ...: ... .   ::   ::....   
NP_005 GGTSDPYVKVFLLPDKKKKFE--TKVHRKTLNPVFNEQFTFKVPYSELGGKTLVMAVYDF
          180       190         200       210       220       230  

        250       260       270       280       290       300      
pF1KSD DRFSRHSVAGELRLGLDGTSVPLGAAQWGELKTSAKEPSAGAGEVLLSISYLPAANRLLV
       ::::.:.. ::... .. ..    . .: .:... :: .   :.. .:. :.:.:..: :
NP_005 DRFSKHDIIGEFKVPMNTVDFGHVTEEWRDLQSAEKEEQEKLGDICFSLRYVPTAGKLTV
            240       250       260       270       280       290  

        310       320       330       340       350       360      
pF1KSD VLIKAKNLHSNQSKELLGKDVSVKVTLKHQARKLKKKQTKRAKHKINPVWNEMIMFELPD
       :...::::.. .   :  .:  ::. : .....::::.:   :. .:: .:: . ::.: 
NP_005 VILEAKNLKKMDVGGL--SDPYVKIHLMQNGKRLKKKKTTIKKNTLNPYYNESFSFEVPF
            300         310       320       330       340       350

        370       380       390       400       410       420      
pF1KSD DLLQASSVELEVLGQDDSGQSCALGHCSLGLHTSGSERSHWEEMLKNPRRQIAMWHQLHL
       . .:  .: . ::  :  :.. :.:.  .: ...:.:  :: .:: :::: ::.:: :..
NP_005 EQIQKVQVVVTVLDYDKIGKNDAIGKVFVGYNSTGAELRHWSDMLANPRRPIAQWHTLQV
              360       370       380       390       400       410

NP_005 EEEVDAMLAVKK
              420  

>>NP_001129278 (OMIM: 185605) synaptotagmin-1 isoform 1   (422 aa)
 initn: 562 init1: 272 opt: 510  Z-score: 495.8  bits: 100.8 E(85289): 7.1e-21
Smith-Waterman score: 510; 32.6% identity (66.3% similar) in 270 aa overlap (161-426:145-410)

              140       150       160       170       180          
pF1KSD FILPQNGVVEDVCVMETWNPEKAASWNQAPKLHYCLDYDCQKAELFVTRLEAV---TSNH
                                     ::.: :::: :. .:.:  ..:.   . . 
NP_001 KDQALKDDDAETGLTDGEEKEEPKEEEKLGKLQYSLDYDFQNNQLLVGIIQAAELPALDM
          120       130       140       150       160       170    

       190        200       210       220       230       240      
pF1KSD DGGCDCYVQGSV-ANRTGSVEAQTALKKRQLHTTWEEGLVLPLAEEELPTATLTLTLRTC
        :  : ::.  .  ..  . :  : .... :. ...: ... .   ::   ::....   
NP_001 GGTSDPYVKVFLLPDKKKKFE--TKVHRKTLNPVFNEQFTFKVPYSELGGKTLVMAVYDF
          180       190         200       210       220       230  

        250       260       270       280       290       300      
pF1KSD DRFSRHSVAGELRLGLDGTSVPLGAAQWGELKTSAKEPSAGAGEVLLSISYLPAANRLLV
       ::::.:.. ::... .. ..    . .: .:... :: .   :.. .:. :.:.:..: :
NP_001 DRFSKHDIIGEFKVPMNTVDFGHVTEEWRDLQSAEKEEQEKLGDICFSLRYVPTAGKLTV
            240       250       260       270       280       290  

        310       320       330       340       350       360      
pF1KSD VLIKAKNLHSNQSKELLGKDVSVKVTLKHQARKLKKKQTKRAKHKINPVWNEMIMFELPD
       :...::::.. .   :  .:  ::. : .....::::.:   :. .:: .:: . ::.: 
NP_001 VILEAKNLKKMDVGGL--SDPYVKIHLMQNGKRLKKKKTTIKKNTLNPYYNESFSFEVPF
            300         310       320       330       340       350

        370       380       390       400       410       420      
pF1KSD DLLQASSVELEVLGQDDSGQSCALGHCSLGLHTSGSERSHWEEMLKNPRRQIAMWHQLHL
       . .:  .: . ::  :  :.. :.:.  .: ...:.:  :: .:: :::: ::.:: :..
NP_001 EQIQKVQVVVTVLDYDKIGKNDAIGKVFVGYNSTGAELRHWSDMLANPRRPIAQWHTLQV
              360       370       380       390       400       410

NP_001 EEEVDAMLAVKK
              420  

>>XP_016875398 (OMIM: 185605) PREDICTED: synaptotagmin-1  (422 aa)
 initn: 562 init1: 272 opt: 510  Z-score: 495.8  bits: 100.8 E(85289): 7.1e-21
Smith-Waterman score: 510; 32.6% identity (66.3% similar) in 270 aa overlap (161-426:145-410)

              140       150       160       170       180          
pF1KSD FILPQNGVVEDVCVMETWNPEKAASWNQAPKLHYCLDYDCQKAELFVTRLEAV---TSNH
                                     ::.: :::: :. .:.:  ..:.   . . 
XP_016 KDQALKDDDAETGLTDGEEKEEPKEEEKLGKLQYSLDYDFQNNQLLVGIIQAAELPALDM
          120       130       140       150       160       170    

       190        200       210       220       230       240      
pF1KSD DGGCDCYVQGSV-ANRTGSVEAQTALKKRQLHTTWEEGLVLPLAEEELPTATLTLTLRTC
        :  : ::.  .  ..  . :  : .... :. ...: ... .   ::   ::....   
XP_016 GGTSDPYVKVFLLPDKKKKFE--TKVHRKTLNPVFNEQFTFKVPYSELGGKTLVMAVYDF
          180       190         200       210       220       230  

        250       260       270       280       290       300      
pF1KSD DRFSRHSVAGELRLGLDGTSVPLGAAQWGELKTSAKEPSAGAGEVLLSISYLPAANRLLV
       ::::.:.. ::... .. ..    . .: .:... :: .   :.. .:. :.:.:..: :
XP_016 DRFSKHDIIGEFKVPMNTVDFGHVTEEWRDLQSAEKEEQEKLGDICFSLRYVPTAGKLTV
            240       250       260       270       280       290  

        310       320       330       340       350       360      
pF1KSD VLIKAKNLHSNQSKELLGKDVSVKVTLKHQARKLKKKQTKRAKHKINPVWNEMIMFELPD
       :...::::.. .   :  .:  ::. : .....::::.:   :. .:: .:: . ::.: 
XP_016 VILEAKNLKKMDVGGL--SDPYVKIHLMQNGKRLKKKKTTIKKNTLNPYYNESFSFEVPF
            300         310       320       330       340       350

        370       380       390       400       410       420      
pF1KSD DLLQASSVELEVLGQDDSGQSCALGHCSLGLHTSGSERSHWEEMLKNPRRQIAMWHQLHL
       . .:  .: . ::  :  :.. :.:.  .: ...:.:  :: .:: :::: ::.:: :..
XP_016 EQIQKVQVVVTVLDYDKIGKNDAIGKVFVGYNSTGAELRHWSDMLANPRRPIAQWHTLQV
              360       370       380       390       400       410

XP_016 EEEVDAMLAVKK
              420  




426 residues in 1 query   sequences
60827320 residues in 85289 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Thu Nov  3 06:12:10 2016 done: Thu Nov  3 06:12:11 2016
 Total Scan time:  9.980 Total Display time:  0.030

Function used was FASTA [36.3.4 Apr, 2011]
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