Result of FASTA (omim) for pF1KSDA1044
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KSDA1044, 630 aa
  1>>>pF1KSDA1044 630 - 630 aa - 630 aa
Library: /omim/omim.rfq.tfa
  60827320 residues in 85289 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 6.0560+/-0.000382; mu= 15.8936+/- 0.024
 mean_var=103.6660+/-20.352, 0's: 0 Z-trim(114.8): 223  B-trim: 622 in 2/49
 Lambda= 0.125967
 statistics sampled from 24500 (24929) to 24500 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.645), E-opt: 0.2 (0.292), width:  16
 Scan time: 11.260

The best scores are:                                      opt bits E(85289)
NP_036413 (OMIM: 605410) potassium voltage-gated c ( 630) 4186 772.0       0
XP_006710693 (OMIM: 605411,607346,616399) PREDICTE ( 636) 3230 598.2 2.8e-170
NP_751948 (OMIM: 605411,607346,616399) potassium v ( 636) 3230 598.2 2.8e-170
NP_004970 (OMIM: 300281) potassium voltage-gated c ( 647) 2797 519.5 1.4e-146
XP_011542212 (OMIM: 300281) PREDICTED: potassium v ( 647) 2797 519.5 1.4e-146
XP_005270908 (OMIM: 605411,607346,616399) PREDICTE ( 655) 2757 512.3 2.2e-144
NP_004971 (OMIM: 605411,607346,616399) potassium v ( 655) 2757 512.3 2.2e-144
XP_016856733 (OMIM: 605411,607346,616399) PREDICTE ( 655) 2757 512.3 2.2e-144
XP_006710692 (OMIM: 605411,607346,616399) PREDICTE ( 655) 2757 512.3 2.2e-144
XP_006710694 (OMIM: 605411,607346,616399) PREDICTE ( 510) 2740 509.1 1.5e-143
XP_011514467 (OMIM: 605410) PREDICTED: potassium v ( 380) 2496 464.7 2.7e-130
XP_016884997 (OMIM: 300281) PREDICTED: potassium v ( 558) 2379 443.5 9.2e-124
XP_016884998 (OMIM: 300281) PREDICTED: potassium v ( 558) 2379 443.5 9.2e-124
XP_006710695 (OMIM: 605411,607346,616399) PREDICTE ( 375) 2133 398.7 1.9e-110
XP_011539728 (OMIM: 605411,607346,616399) PREDICTE ( 387) 2129 398.0 3.3e-110
XP_011539729 (OMIM: 605411,607346,616399) PREDICTE ( 369) 2128 397.8 3.6e-110
XP_011539730 (OMIM: 605411,607346,616399) PREDICTE ( 369) 2128 397.8 3.6e-110
XP_016856734 (OMIM: 605411,607346,616399) PREDICTE ( 407) 2128 397.8 3.9e-110
XP_011539727 (OMIM: 605411,607346,616399) PREDICTE ( 407) 2128 397.8 3.9e-110
XP_016884999 (OMIM: 300281) PREDICTED: potassium v ( 405) 1928 361.5 3.4e-99
NP_004761 (OMIM: 607738) potassium voltage-gated c ( 911)  943 182.7 4.8e-45
XP_011527101 (OMIM: 600397,616056) PREDICTED: pota ( 858)  918 178.2 1.1e-43
NP_004966 (OMIM: 600397,616056) potassium voltage- ( 858)  918 178.2 1.1e-43
XP_006723847 (OMIM: 600397,616056) PREDICTED: pota ( 858)  918 178.2 1.1e-43
NP_002227 (OMIM: 603787) potassium voltage-gated c ( 494)  764 150.0 1.9e-35
NP_002223 (OMIM: 176263) potassium voltage-gated c ( 575)  660 131.1   1e-29
NP_055194 (OMIM: 608164) potassium voltage-gated c ( 500)  659 130.9 1.1e-29
NP_114092 (OMIM: 176268) potassium voltage-gated c ( 456)  656 130.3 1.4e-29
XP_016869470 (OMIM: 607738) PREDICTED: potassium v ( 666)  652 129.7 3.2e-29
XP_016869471 (OMIM: 607738) PREDICTED: potassium v ( 666)  652 129.7 3.2e-29
NP_000208 (OMIM: 160120,176260) potassium voltage- ( 495)  647 128.7 4.7e-29
NP_005540 (OMIM: 602420) potassium voltage-gated c ( 511)  638 127.1 1.5e-28
XP_011531127 (OMIM: 603888) PREDICTED: potassium v ( 491)  560 112.9 2.7e-24
NP_002243 (OMIM: 603888) potassium voltage-gated c ( 491)  560 112.9 2.7e-24
NP_001269357 (OMIM: 603888) potassium voltage-gate ( 491)  560 112.9 2.7e-24
XP_016859548 (OMIM: 603888) PREDICTED: potassium v ( 491)  560 112.9 2.7e-24
NP_065748 (OMIM: 602906) potassium voltage-gated c ( 477)  541 109.4 2.9e-23
XP_011539701 (OMIM: 176262,616366) PREDICTED: pota ( 499)  537 108.7   5e-23
XP_016856702 (OMIM: 176262,616366) PREDICTED: pota ( 499)  537 108.7   5e-23
NP_004965 (OMIM: 176262,616366) potassium voltage- ( 499)  537 108.7   5e-23
XP_011539699 (OMIM: 176262,616366) PREDICTED: pota ( 499)  537 108.7   5e-23
XP_011539702 (OMIM: 176262,616366) PREDICTED: pota ( 499)  537 108.7   5e-23
XP_011539698 (OMIM: 176262,616366) PREDICTED: pota ( 499)  537 108.7   5e-23
XP_011539700 (OMIM: 176262,616366) PREDICTED: pota ( 499)  537 108.7   5e-23
NP_002242 (OMIM: 602905) potassium voltage-gated c ( 526)  512 104.2 1.2e-21
NP_001309728 (OMIM: 602905) potassium voltage-gate ( 526)  512 104.2 1.2e-21
XP_016883335 (OMIM: 602905) PREDICTED: potassium v ( 527)  512 104.2 1.2e-21
NP_002224 (OMIM: 176266) potassium voltage-gated c ( 653)  510 103.9 1.8e-21
NP_002225 (OMIM: 176267,612240) potassium voltage- ( 613)  509 103.7   2e-21
XP_016874760 (OMIM: 176257) PREDICTED: potassium v ( 529)  508 103.5   2e-21


>>NP_036413 (OMIM: 605410) potassium voltage-gated chann  (630 aa)
 initn: 4186 init1: 4186 opt: 4186  Z-score: 4117.0  bits: 772.0 E(85289):    0
Smith-Waterman score: 4186; 100.0% identity (100.0% similar) in 630 aa overlap (1-630:1-630)

               10        20        30        40        50        60
pF1KSD MAAGVAAWLPFARAAAIGWMPVASGPMPAPPRQERKRTQDALIVLNVSGTRFQTWQDTLE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 MAAGVAAWLPFARAAAIGWMPVASGPMPAPPRQERKRTQDALIVLNVSGTRFQTWQDTLE
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KSD RYPDTLLGSSERDFFYHPETQQYFFDRDPDIFRHILNFYRTGKLHYPRHECISAYDEELA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 RYPDTLLGSSERDFFYHPETQQYFFDRDPDIFRHILNFYRTGKLHYPRHECISAYDEELA
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KSD FFGLIPEIIGDCCYEEYKDRRRENAERLQDDADTDTAGESALPTMTARQRVWRAFENPHT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 FFGLIPEIIGDCCYEEYKDRRRENAERLQDDADTDTAGESALPTMTARQRVWRAFENPHT
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KSD STMALVFYYVTGFFIAVSVIANVVETVPCGSSPGHIKELPCGERYAVAFFCLDTACVMIF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 STMALVFYYVTGFFIAVSVIANVVETVPCGSSPGHIKELPCGERYAVAFFCLDTACVMIF
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KSD TVEYLLRLAAAPSRYRFVRSVMSIIDVVAILPYYIGLVMTDNEDVSGAFVTLRVFRVFRI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 TVEYLLRLAAAPSRYRFVRSVMSIIDVVAILPYYIGLVMTDNEDVSGAFVTLRVFRVFRI
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KSD FKFSRHSQGLRILGYTLKSCASELGFLLFSLTMAIIIFATVMFYAEKGSSASKFTSIPAA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 FKFSRHSQGLRILGYTLKSCASELGFLLFSLTMAIIIFATVMFYAEKGSSASKFTSIPAA
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KSD FWYTIVTMTTLGYGDMVPKTIAGKIFGSICSLSGVLVIALPVPVIVSNFSRIYHQNQRAD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 FWYTIVTMTTLGYGDMVPKTIAGKIFGSICSLSGVLVIALPVPVIVSNFSRIYHQNQRAD
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KSD KRRAQKKARLARIRAAKSGSANAYMQSKRNGLLSNQLQSSEDEQAFVSKSGSSFETQHHH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 KRRAQKKARLARIRAAKSGSANAYMQSKRNGLLSNQLQSSEDEQAFVSKSGSSFETQHHH
              430       440       450       460       470       480

              490       500       510       520       530       540
pF1KSD LLHCLEKTTNHEFVDEQVFEESCMEVATVNRPSSHSPSLSSQQGVTSTCCSRRHKKTFRI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 LLHCLEKTTNHEFVDEQVFEESCMEVATVNRPSSHSPSLSSQQGVTSTCCSRRHKKTFRI
              490       500       510       520       530       540

              550       560       570       580       590       600
pF1KSD PNANVSGSHQGSIQELSTIQIRCVERTPLSNSRSSLNAKMEECVKLNCEQPYVTTAIISI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 PNANVSGSHQGSIQELSTIQIRCVERTPLSNSRSSLNAKMEECVKLNCEQPYVTTAIISI
              550       560       570       580       590       600

              610       620       630
pF1KSD PTPPVTTPEGDDRPESPEYSGGNIVRVSAL
       ::::::::::::::::::::::::::::::
NP_036 PTPPVTTPEGDDRPESPEYSGGNIVRVSAL
              610       620       630

>>XP_006710693 (OMIM: 605411,607346,616399) PREDICTED: p  (636 aa)
 initn: 2161 init1: 1482 opt: 3230  Z-score: 3178.0  bits: 598.2 E(85289): 2.8e-170
Smith-Waterman score: 3237; 76.0% identity (89.7% similar) in 641 aa overlap (1-630:1-636)

               10        20        30        40        50        60
pF1KSD MAAGVAAWLPFARAAAIGWMPVASGPMPAPPRQERKRTQDALIVLNVSGTRFQTWQDTLE
       :::::::::::::::::::::::. :::  : .. :: :: :::::::: :::::. :::
XP_006 MAAGVAAWLPFARAAAIGWMPVANCPMPLAPADKNKR-QDELIVLNVSGRRFQTWRTTLE
               10        20        30         40        50         

               70        80        90       100       110       120
pF1KSD RYPDTLLGSSERDFFYHPETQQYFFDRDPDIFRHILNFYRTGKLHYPRHECISAYDEELA
       :::::::::.:..::.. .:..:::::::..:: .:::::::::::::.:::::::.:::
XP_006 RYPDTLLGSTEKEFFFNEDTKEYFFDRDPEVFRCVLNFYRTGKLHYPRYECISAYDDELA
      60        70        80        90       100       110         

              130       140       150       160       170       180
pF1KSD FFGLIPEIIGDCCYEEYKDRRRENAERLQDDADTDTAGESALPTMTARQRVWRAFENPHT
       :.:..:::::::::::::::.:::::::.:: :...  :: .:... :: .:::::::::
XP_006 FYGILPEIIGDCCYEEYKDRKRENAERLMDDNDSENNQES-MPSLSFRQTMWRAFENPHT
     120       130       140       150        160       170        

              190       200       210       220       230       240
pF1KSD STMALVFYYVTGFFIAVSVIANVVETVPCGSSPGHIKELPCGERYAVAFFCLDTACVMIF
       ::.:::::::::::::::::.:::::::::. ::  :::::::::.::::::::::::::
XP_006 STLALVFYYVTGFFIAVSVITNVVETVPCGTVPGS-KELPCGERYSVAFFCLDTACVMIF
      180       190       200       210        220       230       

              250       260       270       280       290       300
pF1KSD TVEYLLRLAAAPSRYRFVRSVMSIIDVVAILPYYIGLVMTDNEDVSGAFVTLRVFRVFRI
       :::::::: ::::::::.::::::::::::.:::::::::.:::::::::::::::::::
XP_006 TVEYLLRLFAAPSRYRFIRSVMSIIDVVAIMPYYIGLVMTNNEDVSGAFVTLRVFRVFRI
       240       250       260       270       280       290       

              310       320       330       340       350       360
pF1KSD FKFSRHSQGLRILGYTLKSCASELGFLLFSLTMAIIIFATVMFYAEKGSSASKFTSIPAA
       :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::.
XP_006 FKFSRHSQGLRILGYTLKSCASELGFLLFSLTMAIIIFATVMFYAEKGSSASKFTSIPAS
       300       310       320       330       340       350       

              370       380       390       400       410       420
pF1KSD FWYTIVTMTTLGYGDMVPKTIAGKIFGSICSLSGVLVIALPVPVIVSNFSRIYHQNQRAD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 FWYTIVTMTTLGYGDMVPKTIAGKIFGSICSLSGVLVIALPVPVIVSNFSRIYHQNQRAD
       360       370       380       390       400       410       

              430       440       450        460       470         
pF1KSD KRRAQKKARLARIRAAKSGSANAYMQSKRNGLLSNQLQ-SSEDEQAFVSKSGSSFETQHH
       ::::::::::::::.::.::.:::..:::::::.. :. ..  :.  ..:. : .:.:::
XP_006 KRRAQKKARLARIRVAKTGSSNAYLHSKRNGLLNEALELTGTPEEEHMGKTTSLIESQHH
       420       430       440       450       460       470       

     480       490       500       510       520       530         
pF1KSD HLLHCLEKTTNHEFVDEQVFEESCMEVATVNRPSSHSPSLSSQQGVTSTCCSRRHKKTFR
       ::::::::::::::.:::.::..::: .  : ::..::::::. :.:.:::::: ::: .
XP_006 HLLHCLEKTTNHEFIDEQMFEQNCMESSMQNYPSTRSPSLSSHPGLTTTCCSRRSKKTTH
       480       490       500       510       520       530       

     540       550       560       570       580       590         
pF1KSD IPNANVSGSHQGSIQELSTIQIRCVERTPLSNSRSSLNAKMEECVKLNCEQPYVTTAIIS
       .::.:. ...  :.::::::.:.  :.  :..:::::: : .. .. ::.   .::::::
XP_006 LPNSNLPATRLRSMQELSTIHIQGSEQPSLTTSRSSLNLKADDGLRPNCKTSQITTAIIS
       540       550       560       570       580       590       

     600       610       620                 630
pF1KSD IPTPPVTTPEGDDRPESPEYSGG----------NIVRVSAL
       :::::. ::::..::  :  : :          :.:.::::
XP_006 IPTPPALTPEGESRP--PPASPGPNTNIPSIASNVVKVSAL
       600       610         620       630      

>>NP_751948 (OMIM: 605411,607346,616399) potassium volta  (636 aa)
 initn: 2161 init1: 1482 opt: 3230  Z-score: 3178.0  bits: 598.2 E(85289): 2.8e-170
Smith-Waterman score: 3237; 76.0% identity (89.7% similar) in 641 aa overlap (1-630:1-636)

               10        20        30        40        50        60
pF1KSD MAAGVAAWLPFARAAAIGWMPVASGPMPAPPRQERKRTQDALIVLNVSGTRFQTWQDTLE
       :::::::::::::::::::::::. :::  : .. :: :: :::::::: :::::. :::
NP_751 MAAGVAAWLPFARAAAIGWMPVANCPMPLAPADKNKR-QDELIVLNVSGRRFQTWRTTLE
               10        20        30         40        50         

               70        80        90       100       110       120
pF1KSD RYPDTLLGSSERDFFYHPETQQYFFDRDPDIFRHILNFYRTGKLHYPRHECISAYDEELA
       :::::::::.:..::.. .:..:::::::..:: .:::::::::::::.:::::::.:::
NP_751 RYPDTLLGSTEKEFFFNEDTKEYFFDRDPEVFRCVLNFYRTGKLHYPRYECISAYDDELA
      60        70        80        90       100       110         

              130       140       150       160       170       180
pF1KSD FFGLIPEIIGDCCYEEYKDRRRENAERLQDDADTDTAGESALPTMTARQRVWRAFENPHT
       :.:..:::::::::::::::.:::::::.:: :...  :: .:... :: .:::::::::
NP_751 FYGILPEIIGDCCYEEYKDRKRENAERLMDDNDSENNQES-MPSLSFRQTMWRAFENPHT
     120       130       140       150        160       170        

              190       200       210       220       230       240
pF1KSD STMALVFYYVTGFFIAVSVIANVVETVPCGSSPGHIKELPCGERYAVAFFCLDTACVMIF
       ::.:::::::::::::::::.:::::::::. ::  :::::::::.::::::::::::::
NP_751 STLALVFYYVTGFFIAVSVITNVVETVPCGTVPGS-KELPCGERYSVAFFCLDTACVMIF
      180       190       200       210        220       230       

              250       260       270       280       290       300
pF1KSD TVEYLLRLAAAPSRYRFVRSVMSIIDVVAILPYYIGLVMTDNEDVSGAFVTLRVFRVFRI
       :::::::: ::::::::.::::::::::::.:::::::::.:::::::::::::::::::
NP_751 TVEYLLRLFAAPSRYRFIRSVMSIIDVVAIMPYYIGLVMTNNEDVSGAFVTLRVFRVFRI
       240       250       260       270       280       290       

              310       320       330       340       350       360
pF1KSD FKFSRHSQGLRILGYTLKSCASELGFLLFSLTMAIIIFATVMFYAEKGSSASKFTSIPAA
       :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::.
NP_751 FKFSRHSQGLRILGYTLKSCASELGFLLFSLTMAIIIFATVMFYAEKGSSASKFTSIPAS
       300       310       320       330       340       350       

              370       380       390       400       410       420
pF1KSD FWYTIVTMTTLGYGDMVPKTIAGKIFGSICSLSGVLVIALPVPVIVSNFSRIYHQNQRAD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_751 FWYTIVTMTTLGYGDMVPKTIAGKIFGSICSLSGVLVIALPVPVIVSNFSRIYHQNQRAD
       360       370       380       390       400       410       

              430       440       450        460       470         
pF1KSD KRRAQKKARLARIRAAKSGSANAYMQSKRNGLLSNQLQ-SSEDEQAFVSKSGSSFETQHH
       ::::::::::::::.::.::.:::..:::::::.. :. ..  :.  ..:. : .:.:::
NP_751 KRRAQKKARLARIRVAKTGSSNAYLHSKRNGLLNEALELTGTPEEEHMGKTTSLIESQHH
       420       430       440       450       460       470       

     480       490       500       510       520       530         
pF1KSD HLLHCLEKTTNHEFVDEQVFEESCMEVATVNRPSSHSPSLSSQQGVTSTCCSRRHKKTFR
       ::::::::::::::.:::.::..::: .  : ::..::::::. :.:.:::::: ::: .
NP_751 HLLHCLEKTTNHEFIDEQMFEQNCMESSMQNYPSTRSPSLSSHPGLTTTCCSRRSKKTTH
       480       490       500       510       520       530       

     540       550       560       570       580       590         
pF1KSD IPNANVSGSHQGSIQELSTIQIRCVERTPLSNSRSSLNAKMEECVKLNCEQPYVTTAIIS
       .::.:. ...  :.::::::.:.  :.  :..:::::: : .. .. ::.   .::::::
NP_751 LPNSNLPATRLRSMQELSTIHIQGSEQPSLTTSRSSLNLKADDGLRPNCKTSQITTAIIS
       540       550       560       570       580       590       

     600       610       620                 630
pF1KSD IPTPPVTTPEGDDRPESPEYSGG----------NIVRVSAL
       :::::. ::::..::  :  : :          :.:.::::
NP_751 IPTPPALTPEGESRP--PPASPGPNTNIPSIASNVVKVSAL
       600       610         620       630      

>>NP_004970 (OMIM: 300281) potassium voltage-gated chann  (647 aa)
 initn: 2012 init1: 1344 opt: 2797  Z-score: 2752.6  bits: 519.5 E(85289): 1.4e-146
Smith-Waterman score: 2797; 67.3% identity (85.8% similar) in 640 aa overlap (1-630:1-632)

               10        20        30        40        50        60
pF1KSD MAAGVAAWLPFARAAAIGWMPVASGPMPAPPRQERKRTQDALIVLNVSGTRFQTWQDTLE
       ::::.:.:::::::::.::.:.:. :.:  :  . .:  : ..:.:::: ::.::..::.
NP_004 MAAGLATWLPFARAAAVGWLPLAQQPLPPAPGVKASRG-DEVLVVNVSGRRFETWKNTLD
               10        20        30         40        50         

               70        80        90       100       110       120
pF1KSD RYPDTLLGSSERDFFYHPETQQYFFDRDPDIFRHILNFYRTGKLHYPRHECISAYDEELA
       :::::::::::..:::  .. .::::::::.:::.:::::::.:: ::.:::.:.:::::
NP_004 RYPDTLLGSSEKEFFYDADSGEYFFDRDPDMFRHVLNFYRTGRLHCPRQECIQAFDEELA
      60        70        80        90       100       110         

              130       140       150       160         170        
pF1KSD FFGLIPEIIGDCCYEEYKDRRRENAERLQDDADTDTAGES-ALPTMTA-RQRVWRAFENP
       :.::.::..:::: :::.::..:::::: .: ... ::.. :::. .. :::.:::::::
NP_004 FYGLVPELVGDCCLEEYRDRKKENAERLAEDEEAEQAGDGPALPAGSSLRQRLWRAFENP
     120       130       140       150       160       170         

      180       190       200        210       220       230       
pF1KSD HTSTMALVFYYVTGFFIAVSVIANVVETVPC-GSSPGHIKELPCGERYAVAFFCLDTACV
       :::: :::::::::::::::::::::::.:: ::.    .: :::::.  ::::.:::::
NP_004 HTSTAALVFYYVTGFFIAVSVIANVVETIPCRGSARRSSREQPCGERFPQAFFCMDTACV
     180       190       200       210       220       230         

       240       250       260       270       280       290       
pF1KSD MIFTVEYLLRLAAAPSRYRFVRSVMSIIDVVAILPYYIGLVMTDNEDVSGAFVTLRVFRV
       .::: :::::: ::::: ::.:::::.:::::::::::::..  :.::::::::::::::
NP_004 LIFTGEYLLRLFAAPSRCRFLRSVMSLIDVVAILPYYIGLLVPKNDDVSGAFVTLRVFRV
     240       250       260       270       280       290         

       300       310       320       330       340       350       
pF1KSD FRIFKFSRHSQGLRILGYTLKSCASELGFLLFSLTMAIIIFATVMFYAEKGSSASKFTSI
       :::::::::::::::::::::::::::::::::::::::::::::::::::.. ..::::
NP_004 FRIFKFSRHSQGLRILGYTLKSCASELGFLLFSLTMAIIIFATVMFYAEKGTNKTNFTSI
     300       310       320       330       340       350         

       360       370       380       390       400       410       
pF1KSD PAAFWYTIVTMTTLGYGDMVPKTIAGKIFGSICSLSGVLVIALPVPVIVSNFSRIYHQNQ
       :::::::::::::::::::::.::::::::::::::::::::::::::::::::::::::
NP_004 PAAFWYTIVTMTTLGYGDMVPSTIAGKIFGSICSLSGVLVIALPVPVIVSNFSRIYHQNQ
     360       370       380       390       400       410         

       420       430       440       450       460       470       
pF1KSD RADKRRAQKKARLARIRAAKSGSANAYMQSKRNGLLSNQLQSSEDEQAFVSKSGSSFETQ
       ::::::::.:.:::::: ::::..::..: :.:: : .  ..: .:::.  .. :.:: :
NP_004 RADKRRAQQKVRLARIRLAKSGTTNAFLQYKQNGGLED--SGSGEEQALCVRNRSAFEQQ
     420       430       440       450         460       470       

       480       490       500       510       520           530   
pF1KSD HHHLLHCLEKTTNHEFVDEQVFEESCMEVATVNRPSSHSPSLSSQQ----GVTSTCCSRR
       :::::::::::: :::.:: .: :.   :.  .: .:.: :.:::     .. :.:: ::
NP_004 HHHLLHCLEKTTCHEFTDELTFSEALGAVSPGGR-TSRSTSVSSQPVGPGSLLSSCCPRR
       480       490       500       510        520       530      

            540       550       560       570       580       590  
pF1KSD HKK-TFRIPNANVSGSHQGSIQELSTIQIRCVERTPLSNSRSSLNAKMEECVKLNCEQPY
        :. ..:. :...: : .::.:::. .    ..:.   .:::::::: .. . :::..  
NP_004 AKRRAIRLANSTASVS-RGSMQELDMLA--GLRRSHAPQSRSSLNAKPHDSLDLNCDSRD
        540       550        560         570       580       590   

            600       610       620         630               
pF1KSD VTTAIISIPTPPVTTPEGDDRPESPEYSG--GNIVRVSAL               
        ..:::::::::..::. ...: ::  .:  :. .: :.:               
NP_004 FVAAIISIPTPPANTPD-ESQPSSPGGGGRAGSTLRNSSLGTPCLFPETVKISSL
           600       610        620       630       640       

>>XP_011542212 (OMIM: 300281) PREDICTED: potassium volta  (647 aa)
 initn: 2012 init1: 1344 opt: 2797  Z-score: 2752.6  bits: 519.5 E(85289): 1.4e-146
Smith-Waterman score: 2797; 67.3% identity (85.8% similar) in 640 aa overlap (1-630:1-632)

               10        20        30        40        50        60
pF1KSD MAAGVAAWLPFARAAAIGWMPVASGPMPAPPRQERKRTQDALIVLNVSGTRFQTWQDTLE
       ::::.:.:::::::::.::.:.:. :.:  :  . .:  : ..:.:::: ::.::..::.
XP_011 MAAGLATWLPFARAAAVGWLPLAQQPLPPAPGVKASRG-DEVLVVNVSGRRFETWKNTLD
               10        20        30         40        50         

               70        80        90       100       110       120
pF1KSD RYPDTLLGSSERDFFYHPETQQYFFDRDPDIFRHILNFYRTGKLHYPRHECISAYDEELA
       :::::::::::..:::  .. .::::::::.:::.:::::::.:: ::.:::.:.:::::
XP_011 RYPDTLLGSSEKEFFYDADSGEYFFDRDPDMFRHVLNFYRTGRLHCPRQECIQAFDEELA
      60        70        80        90       100       110         

              130       140       150       160         170        
pF1KSD FFGLIPEIIGDCCYEEYKDRRRENAERLQDDADTDTAGES-ALPTMTA-RQRVWRAFENP
       :.::.::..:::: :::.::..:::::: .: ... ::.. :::. .. :::.:::::::
XP_011 FYGLVPELVGDCCLEEYRDRKKENAERLAEDEEAEQAGDGPALPAGSSLRQRLWRAFENP
     120       130       140       150       160       170         

      180       190       200        210       220       230       
pF1KSD HTSTMALVFYYVTGFFIAVSVIANVVETVPC-GSSPGHIKELPCGERYAVAFFCLDTACV
       :::: :::::::::::::::::::::::.:: ::.    .: :::::.  ::::.:::::
XP_011 HTSTAALVFYYVTGFFIAVSVIANVVETIPCRGSARRSSREQPCGERFPQAFFCMDTACV
     180       190       200       210       220       230         

       240       250       260       270       280       290       
pF1KSD MIFTVEYLLRLAAAPSRYRFVRSVMSIIDVVAILPYYIGLVMTDNEDVSGAFVTLRVFRV
       .::: :::::: ::::: ::.:::::.:::::::::::::..  :.::::::::::::::
XP_011 LIFTGEYLLRLFAAPSRCRFLRSVMSLIDVVAILPYYIGLLVPKNDDVSGAFVTLRVFRV
     240       250       260       270       280       290         

       300       310       320       330       340       350       
pF1KSD FRIFKFSRHSQGLRILGYTLKSCASELGFLLFSLTMAIIIFATVMFYAEKGSSASKFTSI
       :::::::::::::::::::::::::::::::::::::::::::::::::::.. ..::::
XP_011 FRIFKFSRHSQGLRILGYTLKSCASELGFLLFSLTMAIIIFATVMFYAEKGTNKTNFTSI
     300       310       320       330       340       350         

       360       370       380       390       400       410       
pF1KSD PAAFWYTIVTMTTLGYGDMVPKTIAGKIFGSICSLSGVLVIALPVPVIVSNFSRIYHQNQ
       :::::::::::::::::::::.::::::::::::::::::::::::::::::::::::::
XP_011 PAAFWYTIVTMTTLGYGDMVPSTIAGKIFGSICSLSGVLVIALPVPVIVSNFSRIYHQNQ
     360       370       380       390       400       410         

       420       430       440       450       460       470       
pF1KSD RADKRRAQKKARLARIRAAKSGSANAYMQSKRNGLLSNQLQSSEDEQAFVSKSGSSFETQ
       ::::::::.:.:::::: ::::..::..: :.:: : .  ..: .:::.  .. :.:: :
XP_011 RADKRRAQQKVRLARIRLAKSGTTNAFLQYKQNGGLED--SGSGEEQALCVRNRSAFEQQ
     420       430       440       450         460       470       

       480       490       500       510       520           530   
pF1KSD HHHLLHCLEKTTNHEFVDEQVFEESCMEVATVNRPSSHSPSLSSQQ----GVTSTCCSRR
       :::::::::::: :::.:: .: :.   :.  .: .:.: :.:::     .. :.:: ::
XP_011 HHHLLHCLEKTTCHEFTDELTFSEALGAVSPGGR-TSRSTSVSSQPVGPGSLLSSCCPRR
       480       490       500       510        520       530      

            540       550       560       570       580       590  
pF1KSD HKK-TFRIPNANVSGSHQGSIQELSTIQIRCVERTPLSNSRSSLNAKMEECVKLNCEQPY
        :. ..:. :...: : .::.:::. .    ..:.   .:::::::: .. . :::..  
XP_011 AKRRAIRLANSTASVS-RGSMQELDMLA--GLRRSHAPQSRSSLNAKPHDSLDLNCDSRD
        540       550        560         570       580       590   

            600       610       620         630               
pF1KSD VTTAIISIPTPPVTTPEGDDRPESPEYSG--GNIVRVSAL               
        ..:::::::::..::. ...: ::  .:  :. .: :.:               
XP_011 FVAAIISIPTPPANTPD-ESQPSSPGGGGRAGSTLRNSSLGTPCLFPETVKISSL
           600       610        620       630       640       

>>XP_005270908 (OMIM: 605411,607346,616399) PREDICTED: p  (655 aa)
 initn: 2635 init1: 1482 opt: 2757  Z-score: 2713.2  bits: 512.3 E(85289): 2.2e-144
Smith-Waterman score: 3189; 73.8% identity (87.1% similar) in 660 aa overlap (1-630:1-655)

               10        20        30        40        50        60
pF1KSD MAAGVAAWLPFARAAAIGWMPVASGPMPAPPRQERKRTQDALIVLNVSGTRFQTWQDTLE
       :::::::::::::::::::::::. :::  : .. :: :: :::::::: :::::. :::
XP_005 MAAGVAAWLPFARAAAIGWMPVANCPMPLAPADKNKR-QDELIVLNVSGRRFQTWRTTLE
               10        20        30         40        50         

               70        80        90       100       110       120
pF1KSD RYPDTLLGSSERDFFYHPETQQYFFDRDPDIFRHILNFYRTGKLHYPRHECISAYDEELA
       :::::::::.:..::.. .:..:::::::..:: .:::::::::::::.:::::::.:::
XP_005 RYPDTLLGSTEKEFFFNEDTKEYFFDRDPEVFRCVLNFYRTGKLHYPRYECISAYDDELA
      60        70        80        90       100       110         

              130       140       150       160       170       180
pF1KSD FFGLIPEIIGDCCYEEYKDRRRENAERLQDDADTDTAGESALPTMTARQRVWRAFENPHT
       :.:..:::::::::::::::.:::::::.:: :...  :: .:... :: .:::::::::
XP_005 FYGILPEIIGDCCYEEYKDRKRENAERLMDDNDSENNQES-MPSLSFRQTMWRAFENPHT
     120       130       140       150        160       170        

              190       200       210       220       230       240
pF1KSD STMALVFYYVTGFFIAVSVIANVVETVPCGSSPGHIKELPCGERYAVAFFCLDTACVMIF
       ::.:::::::::::::::::.:::::::::. ::  :::::::::.::::::::::::::
XP_005 STLALVFYYVTGFFIAVSVITNVVETVPCGTVPGS-KELPCGERYSVAFFCLDTACVMIF
      180       190       200       210        220       230       

              250       260       270       280       290       300
pF1KSD TVEYLLRLAAAPSRYRFVRSVMSIIDVVAILPYYIGLVMTDNEDVSGAFVTLRVFRVFRI
       :::::::: ::::::::.::::::::::::.:::::::::.:::::::::::::::::::
XP_005 TVEYLLRLFAAPSRYRFIRSVMSIIDVVAIMPYYIGLVMTNNEDVSGAFVTLRVFRVFRI
       240       250       260       270       280       290       

              310       320       330       340       350       360
pF1KSD FKFSRHSQGLRILGYTLKSCASELGFLLFSLTMAIIIFATVMFYAEKGSSASKFTSIPAA
       :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::.
XP_005 FKFSRHSQGLRILGYTLKSCASELGFLLFSLTMAIIIFATVMFYAEKGSSASKFTSIPAS
       300       310       320       330       340       350       

              370       380       390       400       410       420
pF1KSD FWYTIVTMTTLGYGDMVPKTIAGKIFGSICSLSGVLVIALPVPVIVSNFSRIYHQNQRAD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 FWYTIVTMTTLGYGDMVPKTIAGKIFGSICSLSGVLVIALPVPVIVSNFSRIYHQNQRAD
       360       370       380       390       400       410       

              430       440       450        460       470         
pF1KSD KRRAQKKARLARIRAAKSGSANAYMQSKRNGLLSNQLQ-SSEDEQAFVSKSGSSFETQHH
       ::::::::::::::.::.::.:::..:::::::.. :. ..  :.  ..:. : .:.:::
XP_005 KRRAQKKARLARIRVAKTGSSNAYLHSKRNGLLNEALELTGTPEEEHMGKTTSLIESQHH
       420       430       440       450       460       470       

     480                          490       500       510       520
pF1KSD HLLHCLEKTT-------------------NHEFVDEQVFEESCMEVATVNRPSSHSPSLS
       ::::::::::                   ::::.:::.::..::: .  : ::..:::::
XP_005 HLLHCLEKTTGLSYLVDDPLLSVRTSTIKNHEFIDEQMFEQNCMESSMQNYPSTRSPSLS
       480       490       500       510       520       530       

              530       540       550       560       570       580
pF1KSD SQQGVTSTCCSRRHKKTFRIPNANVSGSHQGSIQELSTIQIRCVERTPLSNSRSSLNAKM
       :. :.:.:::::: ::: ..::.:. ...  :.::::::.:.  :.  :..:::::: : 
XP_005 SHPGLTTTCCSRRSKKTTHLPNSNLPATRLRSMQELSTIHIQGSEQPSLTTSRSSLNLKA
       540       550       560       570       580       590       

              590       600       610       620                 630
pF1KSD EECVKLNCEQPYVTTAIISIPTPPVTTPEGDDRPESPEYSGG----------NIVRVSAL
       .. .. ::.   .:::::::::::. ::::..::  :  : :          :.:.::::
XP_005 DDGLRPNCKTSQITTAIISIPTPPALTPEGESRP--PPASPGPNTNIPSIASNVVKVSAL
       600       610       620       630         640       650     

>>NP_004971 (OMIM: 605411,607346,616399) potassium volta  (655 aa)
 initn: 2635 init1: 1482 opt: 2757  Z-score: 2713.2  bits: 512.3 E(85289): 2.2e-144
Smith-Waterman score: 3189; 73.8% identity (87.1% similar) in 660 aa overlap (1-630:1-655)

               10        20        30        40        50        60
pF1KSD MAAGVAAWLPFARAAAIGWMPVASGPMPAPPRQERKRTQDALIVLNVSGTRFQTWQDTLE
       :::::::::::::::::::::::. :::  : .. :: :: :::::::: :::::. :::
NP_004 MAAGVAAWLPFARAAAIGWMPVANCPMPLAPADKNKR-QDELIVLNVSGRRFQTWRTTLE
               10        20        30         40        50         

               70        80        90       100       110       120
pF1KSD RYPDTLLGSSERDFFYHPETQQYFFDRDPDIFRHILNFYRTGKLHYPRHECISAYDEELA
       :::::::::.:..::.. .:..:::::::..:: .:::::::::::::.:::::::.:::
NP_004 RYPDTLLGSTEKEFFFNEDTKEYFFDRDPEVFRCVLNFYRTGKLHYPRYECISAYDDELA
      60        70        80        90       100       110         

              130       140       150       160       170       180
pF1KSD FFGLIPEIIGDCCYEEYKDRRRENAERLQDDADTDTAGESALPTMTARQRVWRAFENPHT
       :.:..:::::::::::::::.:::::::.:: :...  :: .:... :: .:::::::::
NP_004 FYGILPEIIGDCCYEEYKDRKRENAERLMDDNDSENNQES-MPSLSFRQTMWRAFENPHT
     120       130       140       150        160       170        

              190       200       210       220       230       240
pF1KSD STMALVFYYVTGFFIAVSVIANVVETVPCGSSPGHIKELPCGERYAVAFFCLDTACVMIF
       ::.:::::::::::::::::.:::::::::. ::  :::::::::.::::::::::::::
NP_004 STLALVFYYVTGFFIAVSVITNVVETVPCGTVPGS-KELPCGERYSVAFFCLDTACVMIF
      180       190       200       210        220       230       

              250       260       270       280       290       300
pF1KSD TVEYLLRLAAAPSRYRFVRSVMSIIDVVAILPYYIGLVMTDNEDVSGAFVTLRVFRVFRI
       :::::::: ::::::::.::::::::::::.:::::::::.:::::::::::::::::::
NP_004 TVEYLLRLFAAPSRYRFIRSVMSIIDVVAIMPYYIGLVMTNNEDVSGAFVTLRVFRVFRI
       240       250       260       270       280       290       

              310       320       330       340       350       360
pF1KSD FKFSRHSQGLRILGYTLKSCASELGFLLFSLTMAIIIFATVMFYAEKGSSASKFTSIPAA
       :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::.
NP_004 FKFSRHSQGLRILGYTLKSCASELGFLLFSLTMAIIIFATVMFYAEKGSSASKFTSIPAS
       300       310       320       330       340       350       

              370       380       390       400       410       420
pF1KSD FWYTIVTMTTLGYGDMVPKTIAGKIFGSICSLSGVLVIALPVPVIVSNFSRIYHQNQRAD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 FWYTIVTMTTLGYGDMVPKTIAGKIFGSICSLSGVLVIALPVPVIVSNFSRIYHQNQRAD
       360       370       380       390       400       410       

              430       440       450        460       470         
pF1KSD KRRAQKKARLARIRAAKSGSANAYMQSKRNGLLSNQLQ-SSEDEQAFVSKSGSSFETQHH
       ::::::::::::::.::.::.:::..:::::::.. :. ..  :.  ..:. : .:.:::
NP_004 KRRAQKKARLARIRVAKTGSSNAYLHSKRNGLLNEALELTGTPEEEHMGKTTSLIESQHH
       420       430       440       450       460       470       

     480                          490       500       510       520
pF1KSD HLLHCLEKTT-------------------NHEFVDEQVFEESCMEVATVNRPSSHSPSLS
       ::::::::::                   ::::.:::.::..::: .  : ::..:::::
NP_004 HLLHCLEKTTGLSYLVDDPLLSVRTSTIKNHEFIDEQMFEQNCMESSMQNYPSTRSPSLS
       480       490       500       510       520       530       

              530       540       550       560       570       580
pF1KSD SQQGVTSTCCSRRHKKTFRIPNANVSGSHQGSIQELSTIQIRCVERTPLSNSRSSLNAKM
       :. :.:.:::::: ::: ..::.:. ...  :.::::::.:.  :.  :..:::::: : 
NP_004 SHPGLTTTCCSRRSKKTTHLPNSNLPATRLRSMQELSTIHIQGSEQPSLTTSRSSLNLKA
       540       550       560       570       580       590       

              590       600       610       620                 630
pF1KSD EECVKLNCEQPYVTTAIISIPTPPVTTPEGDDRPESPEYSGG----------NIVRVSAL
       .. .. ::.   .:::::::::::. ::::..::  :  : :          :.:.::::
NP_004 DDGLRPNCKTSQITTAIISIPTPPALTPEGESRP--PPASPGPNTNIPSIASNVVKVSAL
       600       610       620       630         640       650     

>>XP_016856733 (OMIM: 605411,607346,616399) PREDICTED: p  (655 aa)
 initn: 2635 init1: 1482 opt: 2757  Z-score: 2713.2  bits: 512.3 E(85289): 2.2e-144
Smith-Waterman score: 3189; 73.8% identity (87.1% similar) in 660 aa overlap (1-630:1-655)

               10        20        30        40        50        60
pF1KSD MAAGVAAWLPFARAAAIGWMPVASGPMPAPPRQERKRTQDALIVLNVSGTRFQTWQDTLE
       :::::::::::::::::::::::. :::  : .. :: :: :::::::: :::::. :::
XP_016 MAAGVAAWLPFARAAAIGWMPVANCPMPLAPADKNKR-QDELIVLNVSGRRFQTWRTTLE
               10        20        30         40        50         

               70        80        90       100       110       120
pF1KSD RYPDTLLGSSERDFFYHPETQQYFFDRDPDIFRHILNFYRTGKLHYPRHECISAYDEELA
       :::::::::.:..::.. .:..:::::::..:: .:::::::::::::.:::::::.:::
XP_016 RYPDTLLGSTEKEFFFNEDTKEYFFDRDPEVFRCVLNFYRTGKLHYPRYECISAYDDELA
      60        70        80        90       100       110         

              130       140       150       160       170       180
pF1KSD FFGLIPEIIGDCCYEEYKDRRRENAERLQDDADTDTAGESALPTMTARQRVWRAFENPHT
       :.:..:::::::::::::::.:::::::.:: :...  :: .:... :: .:::::::::
XP_016 FYGILPEIIGDCCYEEYKDRKRENAERLMDDNDSENNQES-MPSLSFRQTMWRAFENPHT
     120       130       140       150        160       170        

              190       200       210       220       230       240
pF1KSD STMALVFYYVTGFFIAVSVIANVVETVPCGSSPGHIKELPCGERYAVAFFCLDTACVMIF
       ::.:::::::::::::::::.:::::::::. ::  :::::::::.::::::::::::::
XP_016 STLALVFYYVTGFFIAVSVITNVVETVPCGTVPGS-KELPCGERYSVAFFCLDTACVMIF
      180       190       200       210        220       230       

              250       260       270       280       290       300
pF1KSD TVEYLLRLAAAPSRYRFVRSVMSIIDVVAILPYYIGLVMTDNEDVSGAFVTLRVFRVFRI
       :::::::: ::::::::.::::::::::::.:::::::::.:::::::::::::::::::
XP_016 TVEYLLRLFAAPSRYRFIRSVMSIIDVVAIMPYYIGLVMTNNEDVSGAFVTLRVFRVFRI
       240       250       260       270       280       290       

              310       320       330       340       350       360
pF1KSD FKFSRHSQGLRILGYTLKSCASELGFLLFSLTMAIIIFATVMFYAEKGSSASKFTSIPAA
       :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::.
XP_016 FKFSRHSQGLRILGYTLKSCASELGFLLFSLTMAIIIFATVMFYAEKGSSASKFTSIPAS
       300       310       320       330       340       350       

              370       380       390       400       410       420
pF1KSD FWYTIVTMTTLGYGDMVPKTIAGKIFGSICSLSGVLVIALPVPVIVSNFSRIYHQNQRAD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FWYTIVTMTTLGYGDMVPKTIAGKIFGSICSLSGVLVIALPVPVIVSNFSRIYHQNQRAD
       360       370       380       390       400       410       

              430       440       450        460       470         
pF1KSD KRRAQKKARLARIRAAKSGSANAYMQSKRNGLLSNQLQ-SSEDEQAFVSKSGSSFETQHH
       ::::::::::::::.::.::.:::..:::::::.. :. ..  :.  ..:. : .:.:::
XP_016 KRRAQKKARLARIRVAKTGSSNAYLHSKRNGLLNEALELTGTPEEEHMGKTTSLIESQHH
       420       430       440       450       460       470       

     480                          490       500       510       520
pF1KSD HLLHCLEKTT-------------------NHEFVDEQVFEESCMEVATVNRPSSHSPSLS
       ::::::::::                   ::::.:::.::..::: .  : ::..:::::
XP_016 HLLHCLEKTTGLSYLVDDPLLSVRTSTIKNHEFIDEQMFEQNCMESSMQNYPSTRSPSLS
       480       490       500       510       520       530       

              530       540       550       560       570       580
pF1KSD SQQGVTSTCCSRRHKKTFRIPNANVSGSHQGSIQELSTIQIRCVERTPLSNSRSSLNAKM
       :. :.:.:::::: ::: ..::.:. ...  :.::::::.:.  :.  :..:::::: : 
XP_016 SHPGLTTTCCSRRSKKTTHLPNSNLPATRLRSMQELSTIHIQGSEQPSLTTSRSSLNLKA
       540       550       560       570       580       590       

              590       600       610       620                 630
pF1KSD EECVKLNCEQPYVTTAIISIPTPPVTTPEGDDRPESPEYSGG----------NIVRVSAL
       .. .. ::.   .:::::::::::. ::::..::  :  : :          :.:.::::
XP_016 DDGLRPNCKTSQITTAIISIPTPPALTPEGESRP--PPASPGPNTNIPSIASNVVKVSAL
       600       610       620       630         640       650     

>>XP_006710692 (OMIM: 605411,607346,616399) PREDICTED: p  (655 aa)
 initn: 2635 init1: 1482 opt: 2757  Z-score: 2713.2  bits: 512.3 E(85289): 2.2e-144
Smith-Waterman score: 3189; 73.8% identity (87.1% similar) in 660 aa overlap (1-630:1-655)

               10        20        30        40        50        60
pF1KSD MAAGVAAWLPFARAAAIGWMPVASGPMPAPPRQERKRTQDALIVLNVSGTRFQTWQDTLE
       :::::::::::::::::::::::. :::  : .. :: :: :::::::: :::::. :::
XP_006 MAAGVAAWLPFARAAAIGWMPVANCPMPLAPADKNKR-QDELIVLNVSGRRFQTWRTTLE
               10        20        30         40        50         

               70        80        90       100       110       120
pF1KSD RYPDTLLGSSERDFFYHPETQQYFFDRDPDIFRHILNFYRTGKLHYPRHECISAYDEELA
       :::::::::.:..::.. .:..:::::::..:: .:::::::::::::.:::::::.:::
XP_006 RYPDTLLGSTEKEFFFNEDTKEYFFDRDPEVFRCVLNFYRTGKLHYPRYECISAYDDELA
      60        70        80        90       100       110         

              130       140       150       160       170       180
pF1KSD FFGLIPEIIGDCCYEEYKDRRRENAERLQDDADTDTAGESALPTMTARQRVWRAFENPHT
       :.:..:::::::::::::::.:::::::.:: :...  :: .:... :: .:::::::::
XP_006 FYGILPEIIGDCCYEEYKDRKRENAERLMDDNDSENNQES-MPSLSFRQTMWRAFENPHT
     120       130       140       150        160       170        

              190       200       210       220       230       240
pF1KSD STMALVFYYVTGFFIAVSVIANVVETVPCGSSPGHIKELPCGERYAVAFFCLDTACVMIF
       ::.:::::::::::::::::.:::::::::. ::  :::::::::.::::::::::::::
XP_006 STLALVFYYVTGFFIAVSVITNVVETVPCGTVPGS-KELPCGERYSVAFFCLDTACVMIF
      180       190       200       210        220       230       

              250       260       270       280       290       300
pF1KSD TVEYLLRLAAAPSRYRFVRSVMSIIDVVAILPYYIGLVMTDNEDVSGAFVTLRVFRVFRI
       :::::::: ::::::::.::::::::::::.:::::::::.:::::::::::::::::::
XP_006 TVEYLLRLFAAPSRYRFIRSVMSIIDVVAIMPYYIGLVMTNNEDVSGAFVTLRVFRVFRI
       240       250       260       270       280       290       

              310       320       330       340       350       360
pF1KSD FKFSRHSQGLRILGYTLKSCASELGFLLFSLTMAIIIFATVMFYAEKGSSASKFTSIPAA
       :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::.
XP_006 FKFSRHSQGLRILGYTLKSCASELGFLLFSLTMAIIIFATVMFYAEKGSSASKFTSIPAS
       300       310       320       330       340       350       

              370       380       390       400       410       420
pF1KSD FWYTIVTMTTLGYGDMVPKTIAGKIFGSICSLSGVLVIALPVPVIVSNFSRIYHQNQRAD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 FWYTIVTMTTLGYGDMVPKTIAGKIFGSICSLSGVLVIALPVPVIVSNFSRIYHQNQRAD
       360       370       380       390       400       410       

              430       440       450        460       470         
pF1KSD KRRAQKKARLARIRAAKSGSANAYMQSKRNGLLSNQLQ-SSEDEQAFVSKSGSSFETQHH
       ::::::::::::::.::.::.:::..:::::::.. :. ..  :.  ..:. : .:.:::
XP_006 KRRAQKKARLARIRVAKTGSSNAYLHSKRNGLLNEALELTGTPEEEHMGKTTSLIESQHH
       420       430       440       450       460       470       

     480                          490       500       510       520
pF1KSD HLLHCLEKTT-------------------NHEFVDEQVFEESCMEVATVNRPSSHSPSLS
       ::::::::::                   ::::.:::.::..::: .  : ::..:::::
XP_006 HLLHCLEKTTGLSYLVDDPLLSVRTSTIKNHEFIDEQMFEQNCMESSMQNYPSTRSPSLS
       480       490       500       510       520       530       

              530       540       550       560       570       580
pF1KSD SQQGVTSTCCSRRHKKTFRIPNANVSGSHQGSIQELSTIQIRCVERTPLSNSRSSLNAKM
       :. :.:.:::::: ::: ..::.:. ...  :.::::::.:.  :.  :..:::::: : 
XP_006 SHPGLTTTCCSRRSKKTTHLPNSNLPATRLRSMQELSTIHIQGSEQPSLTTSRSSLNLKA
       540       550       560       570       580       590       

              590       600       610       620                 630
pF1KSD EECVKLNCEQPYVTTAIISIPTPPVTTPEGDDRPESPEYSGG----------NIVRVSAL
       .. .. ::.   .:::::::::::. ::::..::  :  : :          :.:.::::
XP_006 DDGLRPNCKTSQITTAIISIPTPPALTPEGESRP--PPASPGPNTNIPSIASNVVKVSAL
       600       610       620       630         640       650     

>>XP_006710694 (OMIM: 605411,607346,616399) PREDICTED: p  (510 aa)
 initn: 2161 init1: 1482 opt: 2740  Z-score: 2698.0  bits: 509.1 E(85289): 1.5e-143
Smith-Waterman score: 2740; 81.6% identity (93.4% similar) in 501 aa overlap (1-499:1-498)

               10        20        30        40        50        60
pF1KSD MAAGVAAWLPFARAAAIGWMPVASGPMPAPPRQERKRTQDALIVLNVSGTRFQTWQDTLE
       :::::::::::::::::::::::. :::  : .. :: :: :::::::: :::::. :::
XP_006 MAAGVAAWLPFARAAAIGWMPVANCPMPLAPADKNKR-QDELIVLNVSGRRFQTWRTTLE
               10        20        30         40        50         

               70        80        90       100       110       120
pF1KSD RYPDTLLGSSERDFFYHPETQQYFFDRDPDIFRHILNFYRTGKLHYPRHECISAYDEELA
       :::::::::.:..::.. .:..:::::::..:: .:::::::::::::.:::::::.:::
XP_006 RYPDTLLGSTEKEFFFNEDTKEYFFDRDPEVFRCVLNFYRTGKLHYPRYECISAYDDELA
      60        70        80        90       100       110         

              130       140       150       160       170       180
pF1KSD FFGLIPEIIGDCCYEEYKDRRRENAERLQDDADTDTAGESALPTMTARQRVWRAFENPHT
       :.:..:::::::::::::::.:::::::.:: :...  :: .:... :: .:::::::::
XP_006 FYGILPEIIGDCCYEEYKDRKRENAERLMDDNDSENNQES-MPSLSFRQTMWRAFENPHT
     120       130       140       150        160       170        

              190       200       210       220       230       240
pF1KSD STMALVFYYVTGFFIAVSVIANVVETVPCGSSPGHIKELPCGERYAVAFFCLDTACVMIF
       ::.:::::::::::::::::.:::::::::. ::  :::::::::.::::::::::::::
XP_006 STLALVFYYVTGFFIAVSVITNVVETVPCGTVPGS-KELPCGERYSVAFFCLDTACVMIF
      180       190       200       210        220       230       

              250       260       270       280       290       300
pF1KSD TVEYLLRLAAAPSRYRFVRSVMSIIDVVAILPYYIGLVMTDNEDVSGAFVTLRVFRVFRI
       :::::::: ::::::::.::::::::::::.:::::::::.:::::::::::::::::::
XP_006 TVEYLLRLFAAPSRYRFIRSVMSIIDVVAIMPYYIGLVMTNNEDVSGAFVTLRVFRVFRI
       240       250       260       270       280       290       

              310       320       330       340       350       360
pF1KSD FKFSRHSQGLRILGYTLKSCASELGFLLFSLTMAIIIFATVMFYAEKGSSASKFTSIPAA
       :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::.
XP_006 FKFSRHSQGLRILGYTLKSCASELGFLLFSLTMAIIIFATVMFYAEKGSSASKFTSIPAS
       300       310       320       330       340       350       

              370       380       390       400       410       420
pF1KSD FWYTIVTMTTLGYGDMVPKTIAGKIFGSICSLSGVLVIALPVPVIVSNFSRIYHQNQRAD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 FWYTIVTMTTLGYGDMVPKTIAGKIFGSICSLSGVLVIALPVPVIVSNFSRIYHQNQRAD
       360       370       380       390       400       410       

              430       440       450        460       470         
pF1KSD KRRAQKKARLARIRAAKSGSANAYMQSKRNGLLSNQLQ-SSEDEQAFVSKSGSSFETQHH
       ::::::::::::::.::.::.:::..:::::::.. :. ..  :.  ..:. : .:.:::
XP_006 KRRAQKKARLARIRVAKTGSSNAYLHSKRNGLLNEALELTGTPEEEHMGKTTSLIESQHH
       420       430       440       450       460       470       

     480       490        500       510       520       530        
pF1KSD HLLHCLEKTTNHEF-VDEQVFEESCMEVATVNRPSSHSPSLSSQQGVTSTCCSRRHKKTF
       ::::::::::.  . ::. ..                                       
XP_006 HLLHCLEKTTGLSYLVDDPLLSVRTSTIKSLQP                           
       480       490       500       510                           




630 residues in 1 query   sequences
60827320 residues in 85289 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Thu Nov  3 04:42:29 2016 done: Thu Nov  3 04:42:31 2016
 Total Scan time: 11.260 Total Display time:  0.180

Function used was FASTA [36.3.4 Apr, 2011]
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