Result of FASTA (omim) for pF1KSDA0741
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KSDA0741, 1220 aa
  1>>>pF1KSDA0741 1220 - 1220 aa - 1220 aa
Library: /omim/omim.rfq.tfa
  60827320 residues in 85289 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 17.3520+/-0.000657; mu= -34.5962+/- 0.041
 mean_var=832.4769+/-169.903, 0's: 0 Z-trim(120.3): 103  B-trim: 0 in 0/58
 Lambda= 0.044452
 statistics sampled from 35237 (35340) to 35237 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.69), E-opt: 0.2 (0.414), width:  16
 Scan time: 13.130

The best scores are:                                      opt bits E(85289)
NP_056988 (OMIM: 606086) eukaryotic translation in (1220) 7810 517.8 1.7e-145
NP_001778 (OMIM: 176873) cyclin-dependent kinase 1 ( 795)  419 43.6   0.006


>>NP_056988 (OMIM: 606086) eukaryotic translation initia  (1220 aa)
 initn: 7810 init1: 7810 opt: 7810  Z-score: 2733.0  bits: 517.8 E(85289): 1.7e-145
Smith-Waterman score: 7810; 99.9% identity (99.9% similar) in 1220 aa overlap (1-1220:1-1220)

               10        20        30        40        50        60
pF1KSD MGKKQKNKSEDSTKDDIDLDALAAEIEGAGAAKEQEPQKSKGKKKKEKKKQDFDEDDILK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 MGKKQKNKSEDSTKDDIDLDALAAEIEGAGAAKEQEPQKSKGKKKKEKKKQDFDEDDILK
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KSD ELEGLSLEAQGIKADRETVAVKPTENNEEEFTSKDKKKKGQKGKKQSFDDNDSEELEDKD
       ::: ::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 ELEELSLEAQGIKADRETVAVKPTENNEEEFTSKDKKKKGQKGKKQSFDDNDSEELEDKD
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KSD SKSKKTAKPKVEMYSGSDDDDDFNKLPKKAKGKAQKSNKKWDGSEEDEDNSKKIKERSRI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 SKSKKTAKPKVEMYSGSDDDDDFNKLPKKAKGKAQKSNKKWDGSEEDEDNSKKIKERSRI
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KSD NSSGESGDESDEFLQSRKGQKKNQKNKPGPNIESGNEDDDASFKIKTVAQKKAEKKERER
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 NSSGESGDESDEFLQSRKGQKKNQKNKPGPNIESGNEDDDASFKIKTVAQKKAEKKERER
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KSD KKRDEEKAKLRKLKEKEELETGKKDQSKQKESQRKFEEETVKSKVTVDTGVIPASEEKAE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 KKRDEEKAKLRKLKEKEELETGKKDQSKQKESQRKFEEETVKSKVTVDTGVIPASEEKAE
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KSD TPTAAEDDNEGDKKKKDKKKKKGEKEEKEKEKKKGPSKATVKAMQEALAKLKEEEERQKR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 TPTAAEDDNEGDKKKKDKKKKKGEKEEKEKEKKKGPSKATVKAMQEALAKLKEEEERQKR
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KSD EEEERIKRLEELEAKRKEEERLEQEKRERKKQKEKERKERLKKEGKLLTKSQREARARAE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 EEEERIKRLEELEAKRKEEERLEQEKRERKKQKEKERKERLKKEGKLLTKSQREARARAE
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KSD ATLKLLQAQGVEVPSKDSLPKKRPIYEDKKRKKIPQQLESKEVSESMELCAAVEVMEQGV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 ATLKLLQAQGVEVPSKDSLPKKRPIYEDKKRKKIPQQLESKEVSESMELCAAVEVMEQGV
              430       440       450       460       470       480

              490       500       510       520       530       540
pF1KSD PEKEETPPPVEPEEEEDTEDAGLDDWEAMASDEETEKVEGNKVHIEVKENPEEEEEEEEE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 PEKEETPPPVEPEEEEDTEDAGLDDWEAMASDEETEKVEGNKVHIEVKENPEEEEEEEEE
              490       500       510       520       530       540

              550       560       570       580       590       600
pF1KSD EEEDEESEEEEEEEGESEGSEGDEEDEKVSDEKDSGKTLDKKPSKEMSSDSEYDSDDDRT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 EEEDEESEEEEEEEGESEGSEGDEEDEKVSDEKDSGKTLDKKPSKEMSSDSEYDSDDDRT
              550       560       570       580       590       600

              610       620       630       640       650       660
pF1KSD KEERAYDKAKRRIEKRRLEHSKNVNTEKLRAPIICVLGHVDTGKTKILDKLRHTHVQDGE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 KEERAYDKAKRRIEKRRLEHSKNVNTEKLRAPIICVLGHVDTGKTKILDKLRHTHVQDGE
              610       620       630       640       650       660

              670       680       690       700       710       720
pF1KSD AGGITQQIGATNVPLEAINEQTKMIKNFDRENVRIPGMLIIDTPGHESFSNLRNRGSSLC
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 AGGITQQIGATNVPLEAINEQTKMIKNFDRENVRIPGMLIIDTPGHESFSNLRNRGSSLC
              670       680       690       700       710       720

              730       740       750       760       770       780
pF1KSD DIAILVVDIMHGLEPQTIESINLLKSKKCPFIVALNKIDRLYDWKKSPDSDVAATLKKQK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 DIAILVVDIMHGLEPQTIESINLLKSKKCPFIVALNKIDRLYDWKKSPDSDVAATLKKQK
              730       740       750       760       770       780

              790       800       810       820       830       840
pF1KSD KNTKDEFEERAKAIIVEFAQQGLNAALFYENKDPRTFVSLVPTSAHTGDGMGSLIYLLVE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 KNTKDEFEERAKAIIVEFAQQGLNAALFYENKDPRTFVSLVPTSAHTGDGMGSLIYLLVE
              790       800       810       820       830       840

              850       860       870       880       890       900
pF1KSD LTQTMLSKRLAHCEELRAQVMEVKALPGMGTTIDVILINGRLKEGDTIIVPGVEGPIVTQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 LTQTMLSKRLAHCEELRAQVMEVKALPGMGTTIDVILINGRLKEGDTIIVPGVEGPIVTQ
              850       860       870       880       890       900

              910       920       930       940       950       960
pF1KSD IRGLLLPPPMKELRVKNQYEKHKEVEAAQGVKILGKDLEKTLAGLPLLVAYKEDEIPVLK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 IRGLLLPPPMKELRVKNQYEKHKEVEAAQGVKILGKDLEKTLAGLPLLVAYKEDEIPVLK
              910       920       930       940       950       960

              970       980       990      1000      1010      1020
pF1KSD DELIHELKQTLNAIKLEEKGVYVQASTLGSLEALLEFLKTSEVPYAGINIGPVHKKDVMK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 DELIHELKQTLNAIKLEEKGVYVQASTLGSLEALLEFLKTSEVPYAGINIGPVHKKDVMK
              970       980       990      1000      1010      1020

             1030      1040      1050      1060      1070      1080
pF1KSD ASVMLEHDPQYAVILAFDVRIERDAQEMADSLGVRIFSAEIIYHLFDAFTKYRQDYKKQK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 ASVMLEHDPQYAVILAFDVRIERDAQEMADSLGVRIFSAEIIYHLFDAFTKYRQDYKKQK
             1030      1040      1050      1060      1070      1080

             1090      1100      1110      1120      1130      1140
pF1KSD QEEFKHIAVFPCKIKILPQYIFNSRDPIVMGVTVEAGQVKQGTPMCVPSKNFVDIGIVTS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 QEEFKHIAVFPCKIKILPQYIFNSRDPIVMGVTVEAGQVKQGTPMCVPSKNFVDIGIVTS
             1090      1100      1110      1120      1130      1140

             1150      1160      1170      1180      1190      1200
pF1KSD IEINHKQVDVAKKGQEVCVKIEPIPGESPKMFGRHFEATDILVSKISRQSIDALKDWFRD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 IEINHKQVDVAKKGQEVCVKIEPIPGESPKMFGRHFEATDILVSKISRQSIDALKDWFRD
             1150      1160      1170      1180      1190      1200

             1210      1220
pF1KSD EMQKSDWQLIVELKKVFEII
       ::::::::::::::::::::
NP_056 EMQKSDWQLIVELKKVFEII
             1210      1220

>>NP_001778 (OMIM: 176873) cyclin-dependent kinase 11B i  (795 aa)
 initn: 731 init1: 275 opt: 419  Z-score: 173.9  bits: 43.6 E(85289): 0.006
Smith-Waterman score: 443; 26.5% identity (56.8% similar) in 565 aa overlap (215-752:2-535)

          190       200       210       220       230       240    
pF1KSD ESGDESDEFLQSRKGQKKNQKNKPGPNIESGNEDDDASFKIKTVAQKKAEKKERERKKRD
                                     :.: :  :.:.::. .   :::   :.:..
NP_001                              MGDEKD--SWKVKTLDEILQEKK---RRKEQ
                                              10        20         

          250       260       270       280       290       300    
pF1KSD EEKAKLRKLKEKEELETGKKDQSKQKESQRKFEEETVKSKVTVDTGVIPASEEKAETPTA
       ::::....::.... .. :.:. .. : . .  : :....        :  .: .    .
NP_001 EEKAEIKRLKNSDDRDS-KRDSLEEGELRDHRMEITIRNS--------PYRREDSMEDRG
         30        40         50        60                70       

          310          320       330       340       350        360
pF1KSD AEDDNEGDKKKKD---KKKKKGEKEEKEKEKKKGPSKATVKAMQEALAKLKEEE-ERQKR
        :::. . :  ..   :.: . .:.::.:::..  :. .... ..: .: ::.: ::.::
NP_001 EEDDSLAIKPPQQMSRKEKAHHRKDEKRKEKRRHRSH-SAEGGKHARVKEKEREHERRKR
        80        90       100       110        120       130      

              370       380       390          400       410       
pF1KSD EEEERIKRLEELEAKRKEEERLEQEKRERKKQKEKERK---ERLKKEGKLLTKSQREARA
       ..::. :  .: : ....:   :. .::: . .. :::   ::  .: .   . :.: . 
NP_001 HREEQDKARREWERQKRREMAREHSRRERDRLEQLERKRERERKMREQQKEQREQKERER
        140       150       160       170       180       190      

       420       430       440       450       460       470       
pF1KSD RAEATLKLLQAQGVEVPSKDSLPKKRPIYEDKKRKKIPQQLESKEVSESMELCAAVEVME
       :::   :  .:.  :: ..      :  : :: . .  ..   .   : .::  . .  :
NP_001 RAEERRKEREARR-EVSAHHR--TMREDYSDKVKASHWSRSPPRPPRERFELGDGRKPGE
        200        210         220       230       240       250   

       480       490           500       510       520       530   
pF1KSD QGVPEKEETPPPVEPE--EEED--TEDAGLDDWEAMASDEETEKVEGNKVHIEVKENPEE
        . :   . :  .. :  ::.:  ..   ..: :  .:. :. ..:...   : .:. ::
NP_001 -ARPAPAQKPAQLKEEKMEERDLLSDLQDISDSERKTSSAESSSAESGSGSEEEEEEEEE
            260       270       280       290       300       310  

           540       550       560       570       580             
pF1KSD EEEEEEEEEEDEESEEEEEEEGESEGSEGDEEDEKVSDEKDSGKTLDKKPSKEMSS----
       ::::    ::.:: ::::::: :  ::...: .:. : :. : . ...   .:  .    
NP_001 EEEEGSTSEESEEEEEEEEEEEEETGSNSEEASEQ-SAEEVSEEEMSEDEERENENHLLV
            320       330       340        350       360       370 

       590       600            610       620       630       640  
pF1KSD --DSEYDSDDDRTKEER-----AYDKAKRRIEKRRLEHSKNVNTEKLRAPIICVLGHVDT
         .:..: :. ...: .     .  ...   :   .  :  ..  .:.  .   :  .. 
NP_001 VPESRFDRDSGESEEAEEEVGEGTPQSSALTEGDYVPDSPALSPIELKQELPKYLPALQ-
             380       390       400       410       420       430 

            650       660       670       680       690       700  
pF1KSD GKTKILDKLRHTHVQDGEAGGITQQIGATNVPLEAINEQTKMIKNFDRENVRIPGMLIID
       :  .. .    .....:  : . .     .  . :. .. :: :  ..:.  : ..  :.
NP_001 GCRSVEEFQCLNRIEEGTYGVVYRAKDKKTDEIVAL-KRLKMEK--EKEGFPITSLREIN
              440       450       460        470         480       

               710         720       730       740       750       
pF1KSD T---PGHESFSNLRN--RGSSLCDIAILVVDIMHGLEPQTIESINLLKSKKCPFIVALNK
       :     : .. ..:.   ::..  : :..  . : :.       .:... : ::.     
NP_001 TILKAQHPNIVTVREIVVGSNMDKIYIVMNYVEHDLK-------SLMETMKQPFLPGEVK
       490       500       510       520              530       540

       760       770       780       790       800       810       
pF1KSD IDRLYDWKKSPDSDVAATLKKQKKNTKDEFEERAKAIIVEFAQQGLNAALFYENKDPRTF
                                                                   
NP_001 TLMIQLLRGVKHLHDNWILHRDLKTSNLLLSHAGILKVGDFGLAREYGSPLKAYTPVVVT
              550       560       570       580       590       600




1220 residues in 1 query   sequences
60827320 residues in 85289 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Thu Nov  3 02:52:56 2016 done: Thu Nov  3 02:52:58 2016
 Total Scan time: 13.130 Total Display time:  0.010

Function used was FASTA [36.3.4 Apr, 2011]
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