Result of FASTA (omim) for pF1KSDA0388
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KSDA0388, 747 aa
  1>>>pF1KSDA0388 747 - 747 aa - 747 aa
Library: /omim/omim.rfq.tfa
  60827320 residues in 85289 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 6.5493+/-0.000415; mu= 15.5230+/- 0.026
 mean_var=143.9707+/-27.585, 0's: 0 Z-trim(116.7): 179  B-trim: 227 in 1/54
 Lambda= 0.106890
 statistics sampled from 27862 (28043) to 27862 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.682), E-opt: 0.2 (0.329), width:  16
 Scan time: 11.760

The best scores are:                                      opt bits E(85289)
NP_001982 (OMIM: 601674) histone-lysine N-methyltr ( 747) 5206 815.3       0
NP_001308008 (OMIM: 601674) histone-lysine N-methy ( 753) 5206 815.3       0
NP_001308010 (OMIM: 601674) histone-lysine N-methy ( 738) 4666 732.0 2.1e-210
XP_011522819 (OMIM: 601674) PREDICTED: histone-lys ( 744) 4666 732.0 2.1e-210
XP_016879839 (OMIM: 601674) PREDICTED: histone-lys ( 668) 4664 731.6 2.4e-210
NP_001308011 (OMIM: 601674) histone-lysine N-methy ( 707) 4383 688.3 2.8e-197
XP_005257202 (OMIM: 601674) PREDICTED: histone-lys ( 713) 4383 688.3 2.8e-197
XP_016879840 (OMIM: 601674) PREDICTED: histone-lys ( 637) 4382 688.1 2.9e-197
XP_016879841 (OMIM: 601674) PREDICTED: histone-lys ( 410) 2879 456.2 1.3e-127
NP_001190176 (OMIM: 277590,601573) histone-lysine  ( 746) 2701 429.0 3.5e-119
XP_005250019 (OMIM: 277590,601573) PREDICTED: hist ( 754) 2701 429.0 3.5e-119
XP_011514186 (OMIM: 277590,601573) PREDICTED: hist ( 751) 2624 417.1 1.3e-115
NP_004447 (OMIM: 277590,601573) histone-lysine N-m ( 751) 2624 417.1 1.3e-115
XP_011514185 (OMIM: 277590,601573) PREDICTED: hist ( 759) 2624 417.1 1.3e-115
XP_016867306 (OMIM: 277590,601573) PREDICTED: hist ( 759) 2624 417.1 1.3e-115
XP_011514189 (OMIM: 277590,601573) PREDICTED: hist ( 742) 2599 413.2 1.9e-114
XP_011514190 (OMIM: 277590,601573) PREDICTED: hist ( 742) 2599 413.2 1.9e-114
XP_011514187 (OMIM: 277590,601573) PREDICTED: hist ( 750) 2599 413.2 1.9e-114
NP_001190177 (OMIM: 277590,601573) histone-lysine  ( 737) 2491 396.6 1.9e-109
XP_005250020 (OMIM: 277590,601573) PREDICTED: hist ( 745) 2491 396.6  2e-109
XP_016867307 (OMIM: 277590,601573) PREDICTED: hist ( 738) 2487 396.0  3e-109
XP_016867310 (OMIM: 277590,601573) PREDICTED: hist ( 637) 2420 385.6 3.5e-106
XP_011514193 (OMIM: 277590,601573) PREDICTED: hist ( 718) 2413 384.5  8e-106
XP_011514191 (OMIM: 277590,601573) PREDICTED: hist ( 729) 2410 384.1 1.1e-105
XP_011514188 (OMIM: 277590,601573) PREDICTED: hist ( 743) 2410 384.1 1.1e-105
NP_694543 (OMIM: 277590,601573) histone-lysine N-m ( 707) 2354 375.4 4.3e-103
XP_011514195 (OMIM: 277590,601573) PREDICTED: hist ( 715) 2354 375.4 4.4e-103
XP_011514199 (OMIM: 277590,601573) PREDICTED: hist ( 642) 2343 373.7 1.3e-102
XP_011514200 (OMIM: 277590,601573) PREDICTED: hist ( 642) 2343 373.7 1.3e-102
XP_011514196 (OMIM: 277590,601573) PREDICTED: hist ( 712) 2266 361.9 5.3e-99
XP_011514192 (OMIM: 277590,601573) PREDICTED: hist ( 720) 2266 361.9 5.3e-99
XP_016867309 (OMIM: 277590,601573) PREDICTED: hist ( 703) 2260 360.9 9.9e-99
XP_011514197 (OMIM: 277590,601573) PREDICTED: hist ( 711) 2260 360.9   1e-98
XP_011514198 (OMIM: 277590,601573) PREDICTED: hist ( 673) 1262 207.0 2.1e-52
NP_001190178 (OMIM: 277590,601573) histone-lysine  ( 695) 1262 207.0 2.1e-52
XP_005250021 (OMIM: 277590,601573) PREDICTED: hist ( 703) 1262 207.0 2.1e-52
XP_016867308 (OMIM: 277590,601573) PREDICTED: hist ( 712) 1262 207.0 2.1e-52
XP_011514194 (OMIM: 277590,601573) PREDICTED: hist ( 717) 1262 207.0 2.2e-52
XP_011514203 (OMIM: 277590,601573) PREDICTED: hist ( 432)  736 125.7 3.9e-28
XP_011514201 (OMIM: 277590,601573) PREDICTED: hist ( 511)  736 125.8 4.4e-28
NP_003164 (OMIM: 300254) histone-lysine N-methyltr ( 412)  347 65.7 4.4e-10
NP_001269095 (OMIM: 300254) histone-lysine N-methy ( 423)  347 65.7 4.4e-10
XP_016864077 (OMIM: 194190,602952) PREDICTED: hist ( 584)  347 65.9 5.6e-10
XP_016864076 (OMIM: 194190,602952) PREDICTED: hist ( 584)  347 65.9 5.6e-10
XP_011511862 (OMIM: 194190,602952) PREDICTED: hist ( 584)  347 65.9 5.6e-10
NP_075447 (OMIM: 607083) histone-lysine N-methyltr (1437)  351 66.9 6.8e-10
XP_005248059 (OMIM: 194190,602952) PREDICTED: hist (1296)  347 66.2 9.7e-10
NP_001035889 (OMIM: 194190,602952) histone-lysine  (1365)  347 66.2   1e-09
NP_579878 (OMIM: 194190,602952) histone-lysine N-m (1365)  347 66.2   1e-09
XP_011511859 (OMIM: 194190,602952) PREDICTED: hist (1365)  347 66.2   1e-09


>>NP_001982 (OMIM: 601674) histone-lysine N-methyltransf  (747 aa)
 initn: 5206 init1: 5206 opt: 5206  Z-score: 4348.4  bits: 815.3 E(85289):    0
Smith-Waterman score: 5206; 100.0% identity (100.0% similar) in 747 aa overlap (1-747:1-747)

               10        20        30        40        50        60
pF1KSD MEIPNPPTSKCITYWKRKVKSEYMRLRQLKRLQANMGAKALYVANFAKVQEKTQILNEEW
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MEIPNPPTSKCITYWKRKVKSEYMRLRQLKRLQANMGAKALYVANFAKVQEKTQILNEEW
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KSD KKLRVQPVQSMKPVSGHPFLKKCTIESIFPGFASQHMLMRSLNTVALVPIMYSWSPLQQN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KKLRVQPVQSMKPVSGHPFLKKCTIESIFPGFASQHMLMRSLNTVALVPIMYSWSPLQQN
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KSD FMVEDETVLCNIPYMGDEVKEEDETFIEELINNYDGKVHGEEEMIPGSVLISDAVFLELV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FMVEDETVLCNIPYMGDEVKEEDETFIEELINNYDGKVHGEEEMIPGSVLISDAVFLELV
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KSD DALNQYSDEEEEGHNDTSDGKQDDSKEDLPVTRKRKRHAIEGNKKSSKKQFPNDMIFSAI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DALNQYSDEEEEGHNDTSDGKQDDSKEDLPVTRKRKRHAIEGNKKSSKKQFPNDMIFSAI
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KSD ASMFPENGVPDDMKERYRELTEMSDPNALPPQCTPNIDGPNAKSVQREQSLHSFHTLFCR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ASMFPENGVPDDMKERYRELTEMSDPNALPPQCTPNIDGPNAKSVQREQSLHSFHTLFCR
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KSD RCFKYDCFLHPFHATPNVYKRKNKEIKIEPEPCGTDCFLLLEGAKEYAMLHNPRSKCSGR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RCFKYDCFLHPFHATPNVYKRKNKEIKIEPEPCGTDCFLLLEGAKEYAMLHNPRSKCSGR
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KSD RRRRHHIVSASCSNASASAVAETKEGDSDRDTGNDWASSSSEANSRCQTPTKQKASPAPP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RRRRHHIVSASCSNASASAVAETKEGDSDRDTGNDWASSSSEANSRCQTPTKQKASPAPP
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KSD QLCVVEAPSEPVEWTGAEESLFRVFHGTYFNNFCSIARLLGTKTCKQVFQFAVKESLILK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QLCVVEAPSEPVEWTGAEESLFRVFHGTYFNNFCSIARLLGTKTCKQVFQFAVKESLILK
              430       440       450       460       470       480

              490       500       510       520       530       540
pF1KSD LPTDELMNPSQKKKRKHRLWAAHCRKIQLKKDNSSTQVYNYQPCDHPDRPCDSTCPCIMT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LPTDELMNPSQKKKRKHRLWAAHCRKIQLKKDNSSTQVYNYQPCDHPDRPCDSTCPCIMT
              490       500       510       520       530       540

              550       560       570       580       590       600
pF1KSD QNFCEKFCQCNPDCQNRFPGCRCKTQCNTKQCPCYLAVRECDPDLCLTCGASEHWDCKVV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QNFCEKFCQCNPDCQNRFPGCRCKTQCNTKQCPCYLAVRECDPDLCLTCGASEHWDCKVV
              550       560       570       580       590       600

              610       620       630       640       650       660
pF1KSD SCKNCSIQRGLKKHLLLAPSDVAGWGTFIKESVQKNEFISEYCGELISQDEADRRGKVYD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SCKNCSIQRGLKKHLLLAPSDVAGWGTFIKESVQKNEFISEYCGELISQDEADRRGKVYD
              610       620       630       640       650       660

              670       680       690       700       710       720
pF1KSD KYMSSFLFNLNNDFVVDATRKGNKIRFANHSVNPNCYAKVVMVNGDHRIGIFAKRAIQAG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KYMSSFLFNLNNDFVVDATRKGNKIRFANHSVNPNCYAKVVMVNGDHRIGIFAKRAIQAG
              670       680       690       700       710       720

              730       740       
pF1KSD EELFFDYRYSQADALKYVGIERETDVL
       :::::::::::::::::::::::::::
NP_001 EELFFDYRYSQADALKYVGIERETDVL
              730       740       

>>NP_001308008 (OMIM: 601674) histone-lysine N-methyltra  (753 aa)
 initn: 5206 init1: 5206 opt: 5206  Z-score: 4348.4  bits: 815.3 E(85289):    0
Smith-Waterman score: 5206; 100.0% identity (100.0% similar) in 747 aa overlap (1-747:7-753)

                     10        20        30        40        50    
pF1KSD       MEIPNPPTSKCITYWKRKVKSEYMRLRQLKRLQANMGAKALYVANFAKVQEKTQ
             ::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MEDYSKMEIPNPPTSKCITYWKRKVKSEYMRLRQLKRLQANMGAKALYVANFAKVQEKTQ
               10        20        30        40        50        60

           60        70        80        90       100       110    
pF1KSD ILNEEWKKLRVQPVQSMKPVSGHPFLKKCTIESIFPGFASQHMLMRSLNTVALVPIMYSW
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ILNEEWKKLRVQPVQSMKPVSGHPFLKKCTIESIFPGFASQHMLMRSLNTVALVPIMYSW
               70        80        90       100       110       120

          120       130       140       150       160       170    
pF1KSD SPLQQNFMVEDETVLCNIPYMGDEVKEEDETFIEELINNYDGKVHGEEEMIPGSVLISDA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SPLQQNFMVEDETVLCNIPYMGDEVKEEDETFIEELINNYDGKVHGEEEMIPGSVLISDA
              130       140       150       160       170       180

          180       190       200       210       220       230    
pF1KSD VFLELVDALNQYSDEEEEGHNDTSDGKQDDSKEDLPVTRKRKRHAIEGNKKSSKKQFPND
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VFLELVDALNQYSDEEEEGHNDTSDGKQDDSKEDLPVTRKRKRHAIEGNKKSSKKQFPND
              190       200       210       220       230       240

          240       250       260       270       280       290    
pF1KSD MIFSAIASMFPENGVPDDMKERYRELTEMSDPNALPPQCTPNIDGPNAKSVQREQSLHSF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MIFSAIASMFPENGVPDDMKERYRELTEMSDPNALPPQCTPNIDGPNAKSVQREQSLHSF
              250       260       270       280       290       300

          300       310       320       330       340       350    
pF1KSD HTLFCRRCFKYDCFLHPFHATPNVYKRKNKEIKIEPEPCGTDCFLLLEGAKEYAMLHNPR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 HTLFCRRCFKYDCFLHPFHATPNVYKRKNKEIKIEPEPCGTDCFLLLEGAKEYAMLHNPR
              310       320       330       340       350       360

          360       370       380       390       400       410    
pF1KSD SKCSGRRRRRHHIVSASCSNASASAVAETKEGDSDRDTGNDWASSSSEANSRCQTPTKQK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SKCSGRRRRRHHIVSASCSNASASAVAETKEGDSDRDTGNDWASSSSEANSRCQTPTKQK
              370       380       390       400       410       420

          420       430       440       450       460       470    
pF1KSD ASPAPPQLCVVEAPSEPVEWTGAEESLFRVFHGTYFNNFCSIARLLGTKTCKQVFQFAVK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ASPAPPQLCVVEAPSEPVEWTGAEESLFRVFHGTYFNNFCSIARLLGTKTCKQVFQFAVK
              430       440       450       460       470       480

          480       490       500       510       520       530    
pF1KSD ESLILKLPTDELMNPSQKKKRKHRLWAAHCRKIQLKKDNSSTQVYNYQPCDHPDRPCDST
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ESLILKLPTDELMNPSQKKKRKHRLWAAHCRKIQLKKDNSSTQVYNYQPCDHPDRPCDST
              490       500       510       520       530       540

          540       550       560       570       580       590    
pF1KSD CPCIMTQNFCEKFCQCNPDCQNRFPGCRCKTQCNTKQCPCYLAVRECDPDLCLTCGASEH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 CPCIMTQNFCEKFCQCNPDCQNRFPGCRCKTQCNTKQCPCYLAVRECDPDLCLTCGASEH
              550       560       570       580       590       600

          600       610       620       630       640       650    
pF1KSD WDCKVVSCKNCSIQRGLKKHLLLAPSDVAGWGTFIKESVQKNEFISEYCGELISQDEADR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 WDCKVVSCKNCSIQRGLKKHLLLAPSDVAGWGTFIKESVQKNEFISEYCGELISQDEADR
              610       620       630       640       650       660

          660       670       680       690       700       710    
pF1KSD RGKVYDKYMSSFLFNLNNDFVVDATRKGNKIRFANHSVNPNCYAKVVMVNGDHRIGIFAK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RGKVYDKYMSSFLFNLNNDFVVDATRKGNKIRFANHSVNPNCYAKVVMVNGDHRIGIFAK
              670       680       690       700       710       720

          720       730       740       
pF1KSD RAIQAGEELFFDYRYSQADALKYVGIERETDVL
       :::::::::::::::::::::::::::::::::
NP_001 RAIQAGEELFFDYRYSQADALKYVGIERETDVL
              730       740       750   

>>NP_001308010 (OMIM: 601674) histone-lysine N-methyltra  (738 aa)
 initn: 4664 init1: 4664 opt: 4666  Z-score: 3898.4  bits: 732.0 E(85289): 2.1e-210
Smith-Waterman score: 5115; 98.8% identity (98.8% similar) in 747 aa overlap (1-747:1-738)

               10        20        30        40        50        60
pF1KSD MEIPNPPTSKCITYWKRKVKSEYMRLRQLKRLQANMGAKALYVANFAKVQEKTQILNEEW
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MEIPNPPTSKCITYWKRKVKSEYMRLRQLKRLQANMGAKALYVANFAKVQEKTQILNEEW
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KSD KKLRVQPVQSMKPVSGHPFLKKCTIESIFPGFASQHMLMRSLNTVALVPIMYSWSPLQQN
       :::::::::::::         ::::::::::::::::::::::::::::::::::::::
NP_001 KKLRVQPVQSMKP---------CTIESIFPGFASQHMLMRSLNTVALVPIMYSWSPLQQN
               70                 80        90       100       110 

              130       140       150       160       170       180
pF1KSD FMVEDETVLCNIPYMGDEVKEEDETFIEELINNYDGKVHGEEEMIPGSVLISDAVFLELV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FMVEDETVLCNIPYMGDEVKEEDETFIEELINNYDGKVHGEEEMIPGSVLISDAVFLELV
             120       130       140       150       160       170 

              190       200       210       220       230       240
pF1KSD DALNQYSDEEEEGHNDTSDGKQDDSKEDLPVTRKRKRHAIEGNKKSSKKQFPNDMIFSAI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DALNQYSDEEEEGHNDTSDGKQDDSKEDLPVTRKRKRHAIEGNKKSSKKQFPNDMIFSAI
             180       190       200       210       220       230 

              250       260       270       280       290       300
pF1KSD ASMFPENGVPDDMKERYRELTEMSDPNALPPQCTPNIDGPNAKSVQREQSLHSFHTLFCR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ASMFPENGVPDDMKERYRELTEMSDPNALPPQCTPNIDGPNAKSVQREQSLHSFHTLFCR
             240       250       260       270       280       290 

              310       320       330       340       350       360
pF1KSD RCFKYDCFLHPFHATPNVYKRKNKEIKIEPEPCGTDCFLLLEGAKEYAMLHNPRSKCSGR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RCFKYDCFLHPFHATPNVYKRKNKEIKIEPEPCGTDCFLLLEGAKEYAMLHNPRSKCSGR
             300       310       320       330       340       350 

              370       380       390       400       410       420
pF1KSD RRRRHHIVSASCSNASASAVAETKEGDSDRDTGNDWASSSSEANSRCQTPTKQKASPAPP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RRRRHHIVSASCSNASASAVAETKEGDSDRDTGNDWASSSSEANSRCQTPTKQKASPAPP
             360       370       380       390       400       410 

              430       440       450       460       470       480
pF1KSD QLCVVEAPSEPVEWTGAEESLFRVFHGTYFNNFCSIARLLGTKTCKQVFQFAVKESLILK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QLCVVEAPSEPVEWTGAEESLFRVFHGTYFNNFCSIARLLGTKTCKQVFQFAVKESLILK
             420       430       440       450       460       470 

              490       500       510       520       530       540
pF1KSD LPTDELMNPSQKKKRKHRLWAAHCRKIQLKKDNSSTQVYNYQPCDHPDRPCDSTCPCIMT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LPTDELMNPSQKKKRKHRLWAAHCRKIQLKKDNSSTQVYNYQPCDHPDRPCDSTCPCIMT
             480       490       500       510       520       530 

              550       560       570       580       590       600
pF1KSD QNFCEKFCQCNPDCQNRFPGCRCKTQCNTKQCPCYLAVRECDPDLCLTCGASEHWDCKVV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QNFCEKFCQCNPDCQNRFPGCRCKTQCNTKQCPCYLAVRECDPDLCLTCGASEHWDCKVV
             540       550       560       570       580       590 

              610       620       630       640       650       660
pF1KSD SCKNCSIQRGLKKHLLLAPSDVAGWGTFIKESVQKNEFISEYCGELISQDEADRRGKVYD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SCKNCSIQRGLKKHLLLAPSDVAGWGTFIKESVQKNEFISEYCGELISQDEADRRGKVYD
             600       610       620       630       640       650 

              670       680       690       700       710       720
pF1KSD KYMSSFLFNLNNDFVVDATRKGNKIRFANHSVNPNCYAKVVMVNGDHRIGIFAKRAIQAG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KYMSSFLFNLNNDFVVDATRKGNKIRFANHSVNPNCYAKVVMVNGDHRIGIFAKRAIQAG
             660       670       680       690       700       710 

              730       740       
pF1KSD EELFFDYRYSQADALKYVGIERETDVL
       :::::::::::::::::::::::::::
NP_001 EELFFDYRYSQADALKYVGIERETDVL
             720       730        

>>XP_011522819 (OMIM: 601674) PREDICTED: histone-lysine   (744 aa)
 initn: 4664 init1: 4664 opt: 4666  Z-score: 3898.4  bits: 732.0 E(85289): 2.1e-210
Smith-Waterman score: 5115; 98.8% identity (98.8% similar) in 747 aa overlap (1-747:7-744)

                     10        20        30        40        50    
pF1KSD       MEIPNPPTSKCITYWKRKVKSEYMRLRQLKRLQANMGAKALYVANFAKVQEKTQ
             ::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MEDYSKMEIPNPPTSKCITYWKRKVKSEYMRLRQLKRLQANMGAKALYVANFAKVQEKTQ
               10        20        30        40        50        60

           60        70        80        90       100       110    
pF1KSD ILNEEWKKLRVQPVQSMKPVSGHPFLKKCTIESIFPGFASQHMLMRSLNTVALVPIMYSW
       :::::::::::::::::::         ::::::::::::::::::::::::::::::::
XP_011 ILNEEWKKLRVQPVQSMKP---------CTIESIFPGFASQHMLMRSLNTVALVPIMYSW
               70                 80        90       100       110 

          120       130       140       150       160       170    
pF1KSD SPLQQNFMVEDETVLCNIPYMGDEVKEEDETFIEELINNYDGKVHGEEEMIPGSVLISDA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SPLQQNFMVEDETVLCNIPYMGDEVKEEDETFIEELINNYDGKVHGEEEMIPGSVLISDA
             120       130       140       150       160       170 

          180       190       200       210       220       230    
pF1KSD VFLELVDALNQYSDEEEEGHNDTSDGKQDDSKEDLPVTRKRKRHAIEGNKKSSKKQFPND
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VFLELVDALNQYSDEEEEGHNDTSDGKQDDSKEDLPVTRKRKRHAIEGNKKSSKKQFPND
             180       190       200       210       220       230 

          240       250       260       270       280       290    
pF1KSD MIFSAIASMFPENGVPDDMKERYRELTEMSDPNALPPQCTPNIDGPNAKSVQREQSLHSF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MIFSAIASMFPENGVPDDMKERYRELTEMSDPNALPPQCTPNIDGPNAKSVQREQSLHSF
             240       250       260       270       280       290 

          300       310       320       330       340       350    
pF1KSD HTLFCRRCFKYDCFLHPFHATPNVYKRKNKEIKIEPEPCGTDCFLLLEGAKEYAMLHNPR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 HTLFCRRCFKYDCFLHPFHATPNVYKRKNKEIKIEPEPCGTDCFLLLEGAKEYAMLHNPR
             300       310       320       330       340       350 

          360       370       380       390       400       410    
pF1KSD SKCSGRRRRRHHIVSASCSNASASAVAETKEGDSDRDTGNDWASSSSEANSRCQTPTKQK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SKCSGRRRRRHHIVSASCSNASASAVAETKEGDSDRDTGNDWASSSSEANSRCQTPTKQK
             360       370       380       390       400       410 

          420       430       440       450       460       470    
pF1KSD ASPAPPQLCVVEAPSEPVEWTGAEESLFRVFHGTYFNNFCSIARLLGTKTCKQVFQFAVK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ASPAPPQLCVVEAPSEPVEWTGAEESLFRVFHGTYFNNFCSIARLLGTKTCKQVFQFAVK
             420       430       440       450       460       470 

          480       490       500       510       520       530    
pF1KSD ESLILKLPTDELMNPSQKKKRKHRLWAAHCRKIQLKKDNSSTQVYNYQPCDHPDRPCDST
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ESLILKLPTDELMNPSQKKKRKHRLWAAHCRKIQLKKDNSSTQVYNYQPCDHPDRPCDST
             480       490       500       510       520       530 

          540       550       560       570       580       590    
pF1KSD CPCIMTQNFCEKFCQCNPDCQNRFPGCRCKTQCNTKQCPCYLAVRECDPDLCLTCGASEH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 CPCIMTQNFCEKFCQCNPDCQNRFPGCRCKTQCNTKQCPCYLAVRECDPDLCLTCGASEH
             540       550       560       570       580       590 

          600       610       620       630       640       650    
pF1KSD WDCKVVSCKNCSIQRGLKKHLLLAPSDVAGWGTFIKESVQKNEFISEYCGELISQDEADR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 WDCKVVSCKNCSIQRGLKKHLLLAPSDVAGWGTFIKESVQKNEFISEYCGELISQDEADR
             600       610       620       630       640       650 

          660       670       680       690       700       710    
pF1KSD RGKVYDKYMSSFLFNLNNDFVVDATRKGNKIRFANHSVNPNCYAKVVMVNGDHRIGIFAK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RGKVYDKYMSSFLFNLNNDFVVDATRKGNKIRFANHSVNPNCYAKVVMVNGDHRIGIFAK
             660       670       680       690       700       710 

          720       730       740       
pF1KSD RAIQAGEELFFDYRYSQADALKYVGIERETDVL
       :::::::::::::::::::::::::::::::::
XP_011 RAIQAGEELFFDYRYSQADALKYVGIERETDVL
             720       730       740    

>>XP_016879839 (OMIM: 601674) PREDICTED: histone-lysine   (668 aa)
 initn: 4664 init1: 4664 opt: 4664  Z-score: 3897.3  bits: 731.6 E(85289): 2.4e-210
Smith-Waterman score: 4664; 99.7% identity (99.9% similar) in 668 aa overlap (80-747:1-668)

      50        60        70        80        90       100         
pF1KSD QEKTQILNEEWKKLRVQPVQSMKPVSGHPFLKKCTIESIFPGFASQHMLMRSLNTVALVP
                                     .: :::::::::::::::::::::::::::
XP_016                               MKPCTIESIFPGFASQHMLMRSLNTVALVP
                                             10        20        30

     110       120       130       140       150       160         
pF1KSD IMYSWSPLQQNFMVEDETVLCNIPYMGDEVKEEDETFIEELINNYDGKVHGEEEMIPGSV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IMYSWSPLQQNFMVEDETVLCNIPYMGDEVKEEDETFIEELINNYDGKVHGEEEMIPGSV
               40        50        60        70        80        90

     170       180       190       200       210       220         
pF1KSD LISDAVFLELVDALNQYSDEEEEGHNDTSDGKQDDSKEDLPVTRKRKRHAIEGNKKSSKK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LISDAVFLELVDALNQYSDEEEEGHNDTSDGKQDDSKEDLPVTRKRKRHAIEGNKKSSKK
              100       110       120       130       140       150

     230       240       250       260       270       280         
pF1KSD QFPNDMIFSAIASMFPENGVPDDMKERYRELTEMSDPNALPPQCTPNIDGPNAKSVQREQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QFPNDMIFSAIASMFPENGVPDDMKERYRELTEMSDPNALPPQCTPNIDGPNAKSVQREQ
              160       170       180       190       200       210

     290       300       310       320       330       340         
pF1KSD SLHSFHTLFCRRCFKYDCFLHPFHATPNVYKRKNKEIKIEPEPCGTDCFLLLEGAKEYAM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SLHSFHTLFCRRCFKYDCFLHPFHATPNVYKRKNKEIKIEPEPCGTDCFLLLEGAKEYAM
              220       230       240       250       260       270

     350       360       370       380       390       400         
pF1KSD LHNPRSKCSGRRRRRHHIVSASCSNASASAVAETKEGDSDRDTGNDWASSSSEANSRCQT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LHNPRSKCSGRRRRRHHIVSASCSNASASAVAETKEGDSDRDTGNDWASSSSEANSRCQT
              280       290       300       310       320       330

     410       420       430       440       450       460         
pF1KSD PTKQKASPAPPQLCVVEAPSEPVEWTGAEESLFRVFHGTYFNNFCSIARLLGTKTCKQVF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PTKQKASPAPPQLCVVEAPSEPVEWTGAEESLFRVFHGTYFNNFCSIARLLGTKTCKQVF
              340       350       360       370       380       390

     470       480       490       500       510       520         
pF1KSD QFAVKESLILKLPTDELMNPSQKKKRKHRLWAAHCRKIQLKKDNSSTQVYNYQPCDHPDR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QFAVKESLILKLPTDELMNPSQKKKRKHRLWAAHCRKIQLKKDNSSTQVYNYQPCDHPDR
              400       410       420       430       440       450

     530       540       550       560       570       580         
pF1KSD PCDSTCPCIMTQNFCEKFCQCNPDCQNRFPGCRCKTQCNTKQCPCYLAVRECDPDLCLTC
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PCDSTCPCIMTQNFCEKFCQCNPDCQNRFPGCRCKTQCNTKQCPCYLAVRECDPDLCLTC
              460       470       480       490       500       510

     590       600       610       620       630       640         
pF1KSD GASEHWDCKVVSCKNCSIQRGLKKHLLLAPSDVAGWGTFIKESVQKNEFISEYCGELISQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GASEHWDCKVVSCKNCSIQRGLKKHLLLAPSDVAGWGTFIKESVQKNEFISEYCGELISQ
              520       530       540       550       560       570

     650       660       670       680       690       700         
pF1KSD DEADRRGKVYDKYMSSFLFNLNNDFVVDATRKGNKIRFANHSVNPNCYAKVVMVNGDHRI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DEADRRGKVYDKYMSSFLFNLNNDFVVDATRKGNKIRFANHSVNPNCYAKVVMVNGDHRI
              580       590       600       610       620       630

     710       720       730       740       
pF1KSD GIFAKRAIQAGEELFFDYRYSQADALKYVGIERETDVL
       ::::::::::::::::::::::::::::::::::::::
XP_016 GIFAKRAIQAGEELFFDYRYSQADALKYVGIERETDVL
              640       650       660        

>>NP_001308011 (OMIM: 601674) histone-lysine N-methyltra  (707 aa)
 initn: 4382 init1: 4382 opt: 4383  Z-score: 3662.8  bits: 688.3 E(85289): 2.8e-197
Smith-Waterman score: 4842; 94.6% identity (94.6% similar) in 747 aa overlap (1-747:1-707)

               10        20        30        40        50        60
pF1KSD MEIPNPPTSKCITYWKRKVKSEYMRLRQLKRLQANMGAKALYVANFAKVQEKTQILNEEW
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MEIPNPPTSKCITYWKRKVKSEYMRLRQLKRLQANMGAKALYVANFAKVQEKTQILNEEW
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KSD KKLRVQPVQSMKPVSGHPFLKKCTIESIFPGFASQHMLMRSLNTVALVPIMYSWSPLQQN
       ::::::::::::::::::::::                                      
NP_001 KKLRVQPVQSMKPVSGHPFLKK--------------------------------------
               70        80                                        

              130       140       150       160       170       180
pF1KSD FMVEDETVLCNIPYMGDEVKEEDETFIEELINNYDGKVHGEEEMIPGSVLISDAVFLELV
         ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 --VEDETVLCNIPYMGDEVKEEDETFIEELINNYDGKVHGEEEMIPGSVLISDAVFLELV
               90       100       110       120       130       140

              190       200       210       220       230       240
pF1KSD DALNQYSDEEEEGHNDTSDGKQDDSKEDLPVTRKRKRHAIEGNKKSSKKQFPNDMIFSAI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DALNQYSDEEEEGHNDTSDGKQDDSKEDLPVTRKRKRHAIEGNKKSSKKQFPNDMIFSAI
              150       160       170       180       190       200

              250       260       270       280       290       300
pF1KSD ASMFPENGVPDDMKERYRELTEMSDPNALPPQCTPNIDGPNAKSVQREQSLHSFHTLFCR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ASMFPENGVPDDMKERYRELTEMSDPNALPPQCTPNIDGPNAKSVQREQSLHSFHTLFCR
              210       220       230       240       250       260

              310       320       330       340       350       360
pF1KSD RCFKYDCFLHPFHATPNVYKRKNKEIKIEPEPCGTDCFLLLEGAKEYAMLHNPRSKCSGR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RCFKYDCFLHPFHATPNVYKRKNKEIKIEPEPCGTDCFLLLEGAKEYAMLHNPRSKCSGR
              270       280       290       300       310       320

              370       380       390       400       410       420
pF1KSD RRRRHHIVSASCSNASASAVAETKEGDSDRDTGNDWASSSSEANSRCQTPTKQKASPAPP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RRRRHHIVSASCSNASASAVAETKEGDSDRDTGNDWASSSSEANSRCQTPTKQKASPAPP
              330       340       350       360       370       380

              430       440       450       460       470       480
pF1KSD QLCVVEAPSEPVEWTGAEESLFRVFHGTYFNNFCSIARLLGTKTCKQVFQFAVKESLILK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QLCVVEAPSEPVEWTGAEESLFRVFHGTYFNNFCSIARLLGTKTCKQVFQFAVKESLILK
              390       400       410       420       430       440

              490       500       510       520       530       540
pF1KSD LPTDELMNPSQKKKRKHRLWAAHCRKIQLKKDNSSTQVYNYQPCDHPDRPCDSTCPCIMT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LPTDELMNPSQKKKRKHRLWAAHCRKIQLKKDNSSTQVYNYQPCDHPDRPCDSTCPCIMT
              450       460       470       480       490       500

              550       560       570       580       590       600
pF1KSD QNFCEKFCQCNPDCQNRFPGCRCKTQCNTKQCPCYLAVRECDPDLCLTCGASEHWDCKVV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QNFCEKFCQCNPDCQNRFPGCRCKTQCNTKQCPCYLAVRECDPDLCLTCGASEHWDCKVV
              510       520       530       540       550       560

              610       620       630       640       650       660
pF1KSD SCKNCSIQRGLKKHLLLAPSDVAGWGTFIKESVQKNEFISEYCGELISQDEADRRGKVYD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SCKNCSIQRGLKKHLLLAPSDVAGWGTFIKESVQKNEFISEYCGELISQDEADRRGKVYD
              570       580       590       600       610       620

              670       680       690       700       710       720
pF1KSD KYMSSFLFNLNNDFVVDATRKGNKIRFANHSVNPNCYAKVVMVNGDHRIGIFAKRAIQAG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KYMSSFLFNLNNDFVVDATRKGNKIRFANHSVNPNCYAKVVMVNGDHRIGIFAKRAIQAG
              630       640       650       660       670       680

              730       740       
pF1KSD EELFFDYRYSQADALKYVGIERETDVL
       :::::::::::::::::::::::::::
NP_001 EELFFDYRYSQADALKYVGIERETDVL
              690       700       

>>XP_005257202 (OMIM: 601674) PREDICTED: histone-lysine   (713 aa)
 initn: 4382 init1: 4382 opt: 4383  Z-score: 3662.7  bits: 688.3 E(85289): 2.8e-197
Smith-Waterman score: 4842; 94.6% identity (94.6% similar) in 747 aa overlap (1-747:7-713)

                     10        20        30        40        50    
pF1KSD       MEIPNPPTSKCITYWKRKVKSEYMRLRQLKRLQANMGAKALYVANFAKVQEKTQ
             ::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MEDYSKMEIPNPPTSKCITYWKRKVKSEYMRLRQLKRLQANMGAKALYVANFAKVQEKTQ
               10        20        30        40        50        60

           60        70        80        90       100       110    
pF1KSD ILNEEWKKLRVQPVQSMKPVSGHPFLKKCTIESIFPGFASQHMLMRSLNTVALVPIMYSW
       ::::::::::::::::::::::::::::                                
XP_005 ILNEEWKKLRVQPVQSMKPVSGHPFLKK--------------------------------
               70        80                                        

          120       130       140       150       160       170    
pF1KSD SPLQQNFMVEDETVLCNIPYMGDEVKEEDETFIEELINNYDGKVHGEEEMIPGSVLISDA
               ::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 --------VEDETVLCNIPYMGDEVKEEDETFIEELINNYDGKVHGEEEMIPGSVLISDA
               90       100       110       120       130       140

          180       190       200       210       220       230    
pF1KSD VFLELVDALNQYSDEEEEGHNDTSDGKQDDSKEDLPVTRKRKRHAIEGNKKSSKKQFPND
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 VFLELVDALNQYSDEEEEGHNDTSDGKQDDSKEDLPVTRKRKRHAIEGNKKSSKKQFPND
              150       160       170       180       190       200

          240       250       260       270       280       290    
pF1KSD MIFSAIASMFPENGVPDDMKERYRELTEMSDPNALPPQCTPNIDGPNAKSVQREQSLHSF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MIFSAIASMFPENGVPDDMKERYRELTEMSDPNALPPQCTPNIDGPNAKSVQREQSLHSF
              210       220       230       240       250       260

          300       310       320       330       340       350    
pF1KSD HTLFCRRCFKYDCFLHPFHATPNVYKRKNKEIKIEPEPCGTDCFLLLEGAKEYAMLHNPR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 HTLFCRRCFKYDCFLHPFHATPNVYKRKNKEIKIEPEPCGTDCFLLLEGAKEYAMLHNPR
              270       280       290       300       310       320

          360       370       380       390       400       410    
pF1KSD SKCSGRRRRRHHIVSASCSNASASAVAETKEGDSDRDTGNDWASSSSEANSRCQTPTKQK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SKCSGRRRRRHHIVSASCSNASASAVAETKEGDSDRDTGNDWASSSSEANSRCQTPTKQK
              330       340       350       360       370       380

          420       430       440       450       460       470    
pF1KSD ASPAPPQLCVVEAPSEPVEWTGAEESLFRVFHGTYFNNFCSIARLLGTKTCKQVFQFAVK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 ASPAPPQLCVVEAPSEPVEWTGAEESLFRVFHGTYFNNFCSIARLLGTKTCKQVFQFAVK
              390       400       410       420       430       440

          480       490       500       510       520       530    
pF1KSD ESLILKLPTDELMNPSQKKKRKHRLWAAHCRKIQLKKDNSSTQVYNYQPCDHPDRPCDST
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 ESLILKLPTDELMNPSQKKKRKHRLWAAHCRKIQLKKDNSSTQVYNYQPCDHPDRPCDST
              450       460       470       480       490       500

          540       550       560       570       580       590    
pF1KSD CPCIMTQNFCEKFCQCNPDCQNRFPGCRCKTQCNTKQCPCYLAVRECDPDLCLTCGASEH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 CPCIMTQNFCEKFCQCNPDCQNRFPGCRCKTQCNTKQCPCYLAVRECDPDLCLTCGASEH
              510       520       530       540       550       560

          600       610       620       630       640       650    
pF1KSD WDCKVVSCKNCSIQRGLKKHLLLAPSDVAGWGTFIKESVQKNEFISEYCGELISQDEADR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 WDCKVVSCKNCSIQRGLKKHLLLAPSDVAGWGTFIKESVQKNEFISEYCGELISQDEADR
              570       580       590       600       610       620

          660       670       680       690       700       710    
pF1KSD RGKVYDKYMSSFLFNLNNDFVVDATRKGNKIRFANHSVNPNCYAKVVMVNGDHRIGIFAK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 RGKVYDKYMSSFLFNLNNDFVVDATRKGNKIRFANHSVNPNCYAKVVMVNGDHRIGIFAK
              630       640       650       660       670       680

          720       730       740       
pF1KSD RAIQAGEELFFDYRYSQADALKYVGIERETDVL
       :::::::::::::::::::::::::::::::::
XP_005 RAIQAGEELFFDYRYSQADALKYVGIERETDVL
              690       700       710   

>>XP_016879840 (OMIM: 601674) PREDICTED: histone-lysine   (637 aa)
 initn: 4454 init1: 4382 opt: 4382  Z-score: 3662.5  bits: 688.1 E(85289): 2.9e-197
Smith-Waterman score: 4382; 100.0% identity (100.0% similar) in 625 aa overlap (123-747:13-637)

            100       110       120       130       140       150  
pF1KSD ASQHMLMRSLNTVALVPIMYSWSPLQQNFMVEDETVLCNIPYMGDEVKEEDETFIEELIN
                                     ::::::::::::::::::::::::::::::
XP_016                   MKPVSGHPFLKKVEDETVLCNIPYMGDEVKEEDETFIEELIN
                                 10        20        30        40  

            160       170       180       190       200       210  
pF1KSD NYDGKVHGEEEMIPGSVLISDAVFLELVDALNQYSDEEEEGHNDTSDGKQDDSKEDLPVT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NYDGKVHGEEEMIPGSVLISDAVFLELVDALNQYSDEEEEGHNDTSDGKQDDSKEDLPVT
             50        60        70        80        90       100  

            220       230       240       250       260       270  
pF1KSD RKRKRHAIEGNKKSSKKQFPNDMIFSAIASMFPENGVPDDMKERYRELTEMSDPNALPPQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RKRKRHAIEGNKKSSKKQFPNDMIFSAIASMFPENGVPDDMKERYRELTEMSDPNALPPQ
            110       120       130       140       150       160  

            280       290       300       310       320       330  
pF1KSD CTPNIDGPNAKSVQREQSLHSFHTLFCRRCFKYDCFLHPFHATPNVYKRKNKEIKIEPEP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 CTPNIDGPNAKSVQREQSLHSFHTLFCRRCFKYDCFLHPFHATPNVYKRKNKEIKIEPEP
            170       180       190       200       210       220  

            340       350       360       370       380       390  
pF1KSD CGTDCFLLLEGAKEYAMLHNPRSKCSGRRRRRHHIVSASCSNASASAVAETKEGDSDRDT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 CGTDCFLLLEGAKEYAMLHNPRSKCSGRRRRRHHIVSASCSNASASAVAETKEGDSDRDT
            230       240       250       260       270       280  

            400       410       420       430       440       450  
pF1KSD GNDWASSSSEANSRCQTPTKQKASPAPPQLCVVEAPSEPVEWTGAEESLFRVFHGTYFNN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GNDWASSSSEANSRCQTPTKQKASPAPPQLCVVEAPSEPVEWTGAEESLFRVFHGTYFNN
            290       300       310       320       330       340  

            460       470       480       490       500       510  
pF1KSD FCSIARLLGTKTCKQVFQFAVKESLILKLPTDELMNPSQKKKRKHRLWAAHCRKIQLKKD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FCSIARLLGTKTCKQVFQFAVKESLILKLPTDELMNPSQKKKRKHRLWAAHCRKIQLKKD
            350       360       370       380       390       400  

            520       530       540       550       560       570  
pF1KSD NSSTQVYNYQPCDHPDRPCDSTCPCIMTQNFCEKFCQCNPDCQNRFPGCRCKTQCNTKQC
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NSSTQVYNYQPCDHPDRPCDSTCPCIMTQNFCEKFCQCNPDCQNRFPGCRCKTQCNTKQC
            410       420       430       440       450       460  

            580       590       600       610       620       630  
pF1KSD PCYLAVRECDPDLCLTCGASEHWDCKVVSCKNCSIQRGLKKHLLLAPSDVAGWGTFIKES
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PCYLAVRECDPDLCLTCGASEHWDCKVVSCKNCSIQRGLKKHLLLAPSDVAGWGTFIKES
            470       480       490       500       510       520  

            640       650       660       670       680       690  
pF1KSD VQKNEFISEYCGELISQDEADRRGKVYDKYMSSFLFNLNNDFVVDATRKGNKIRFANHSV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VQKNEFISEYCGELISQDEADRRGKVYDKYMSSFLFNLNNDFVVDATRKGNKIRFANHSV
            530       540       550       560       570       580  

            700       710       720       730       740       
pF1KSD NPNCYAKVVMVNGDHRIGIFAKRAIQAGEELFFDYRYSQADALKYVGIERETDVL
       :::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NPNCYAKVVMVNGDHRIGIFAKRAIQAGEELFFDYRYSQADALKYVGIERETDVL
            590       600       610       620       630       

>>XP_016879841 (OMIM: 601674) PREDICTED: histone-lysine   (410 aa)
 initn: 2879 init1: 2879 opt: 2879  Z-score: 2412.3  bits: 456.2 E(85289): 1.3e-127
Smith-Waterman score: 2879; 99.8% identity (99.8% similar) in 409 aa overlap (339-747:2-410)

      310       320       330       340       350       360        
pF1KSD LHPFHATPNVYKRKNKEIKIEPEPCGTDCFLLLEGAKEYAMLHNPRSKCSGRRRRRHHIV
                                     :: :::::::::::::::::::::::::::
XP_016                              MLLKEGAKEYAMLHNPRSKCSGRRRRRHHIV
                                            10        20        30 

      370       380       390       400       410       420        
pF1KSD SASCSNASASAVAETKEGDSDRDTGNDWASSSSEANSRCQTPTKQKASPAPPQLCVVEAP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SASCSNASASAVAETKEGDSDRDTGNDWASSSSEANSRCQTPTKQKASPAPPQLCVVEAP
              40        50        60        70        80        90 

      430       440       450       460       470       480        
pF1KSD SEPVEWTGAEESLFRVFHGTYFNNFCSIARLLGTKTCKQVFQFAVKESLILKLPTDELMN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SEPVEWTGAEESLFRVFHGTYFNNFCSIARLLGTKTCKQVFQFAVKESLILKLPTDELMN
             100       110       120       130       140       150 

      490       500       510       520       530       540        
pF1KSD PSQKKKRKHRLWAAHCRKIQLKKDNSSTQVYNYQPCDHPDRPCDSTCPCIMTQNFCEKFC
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PSQKKKRKHRLWAAHCRKIQLKKDNSSTQVYNYQPCDHPDRPCDSTCPCIMTQNFCEKFC
             160       170       180       190       200       210 

      550       560       570       580       590       600        
pF1KSD QCNPDCQNRFPGCRCKTQCNTKQCPCYLAVRECDPDLCLTCGASEHWDCKVVSCKNCSIQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QCNPDCQNRFPGCRCKTQCNTKQCPCYLAVRECDPDLCLTCGASEHWDCKVVSCKNCSIQ
             220       230       240       250       260       270 

      610       620       630       640       650       660        
pF1KSD RGLKKHLLLAPSDVAGWGTFIKESVQKNEFISEYCGELISQDEADRRGKVYDKYMSSFLF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RGLKKHLLLAPSDVAGWGTFIKESVQKNEFISEYCGELISQDEADRRGKVYDKYMSSFLF
             280       290       300       310       320       330 

      670       680       690       700       710       720        
pF1KSD NLNNDFVVDATRKGNKIRFANHSVNPNCYAKVVMVNGDHRIGIFAKRAIQAGEELFFDYR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NLNNDFVVDATRKGNKIRFANHSVNPNCYAKVVMVNGDHRIGIFAKRAIQAGEELFFDYR
             340       350       360       370       380       390 

      730       740       
pF1KSD YSQADALKYVGIERETDVL
       :::::::::::::::::::
XP_016 YSQADALKYVGIERETDVL
             400       410

>>NP_001190176 (OMIM: 277590,601573) histone-lysine N-me  (746 aa)
 initn: 3051 init1: 1795 opt: 2701  Z-score: 2260.7  bits: 429.0 E(85289): 3.5e-119
Smith-Waterman score: 3353; 65.0% identity (82.3% similar) in 758 aa overlap (15-746:15-745)

               10        20        30        40        50        60
pF1KSD MEIPNPPTSKCITYWKRKVKSEYMRLRQLKRLQANMGAKALYVANFAKVQEKTQILNEEW
                     :...:::::::::::::..    .:... .:  :. :.:.:::.::
NP_001 MGQTGKKSEKGPVCWRKRVKSEYMRLRQLKRFRRADEVKSMFSSNRQKILERTEILNQEW
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KSD KKLRVQPVQSMKPVSGHPFLKKCTIESIFPGFASQHMLMRSLNTVALVPIMYSWSPLQQN
       :. :.:::. .  ::.    ..:.. : .  : .: . ...::.:: :::::::::::::
NP_001 KQRRIQPVHILTSVSSLRGTRECSVTSDLD-FPTQVIPLKTLNAVASVPIMYSWSPLQQN
               70        80        90        100       110         

              130       140       150       160       170       180
pF1KSD FMVEDETVLCNIPYMGDEVKEEDETFIEELINNYDGKVHGEEEMIPGSVLISDAVFLELV
       ::::::::: ::::::::: ..: :::::::.::::::::..:   :  .:.: .:.:::
NP_001 FMVEDETVLHNIPYMGDEVLDQDGTFIEELIKNYDGKVHGDREC--G--FINDEIFVELV
     120       130       140       150       160           170     

              190       200       210       220           230      
pF1KSD DALNQYSDEEEEGHNDTSDGKQDDSKEDLPVTRKRKRHAIEGNK--KSSK--KQFPNDMI
       .::.::.:..     : .::  :: .:     :..:.. .: ..  : :.  ..::.: :
NP_001 NALGQYNDDD-----DDDDG--DDPEE-----REEKQKDLEDHRDDKESRPPRKFPSDKI
         180            190              200       210       220   

        240       250       260       270       280       290      
pF1KSD FSAIASMFPENGVPDDMKERYRELTEMSDPNALPPQCTPNIDGPNAKSVQREQSLHSFHT
       : ::.::::..:. ...::.:.::::.. :.::::.::::::::::::::::::::::::
NP_001 FEAISSMFPDKGTAEELKEKYKELTEQQLPGALPPECTPNIDGPNAKSVQREQSLHSFHT
           230       240       250       260       270       280   

        300       310       320       330       340             350
pF1KSD LFCRRCFKYDCFLHPFHATPNVYKRKNKEIKIEPEPCGTDCFLLLEGAKEYAM------L
       :::::::::::::::::::::.::::: :  .. .::: .:.  ::::::.:       .
NP_001 LFCRRCFKYDCFLHPFHATPNTYKRKNTETALDNKPCGPQCYQHLEGAKEFAAALTAERI
           290       300       310       320       330       340   

              360       370       380       390                    
pF1KSD HNPRSKCSGRRRRRHHIVSASCSNASASAVAETKEGDSDRDTGN---------------D
       ..: .. .:::: :    :.  :. . . : :.:. ::::..:.               :
NP_001 KTPPKRPGGRRRGRLPNNSSRPSTPTIN-VLESKDTDSDREAGTETGGENNDKEEEEKKD
           350       360       370        380       390       400  

         400       410       420       430       440       450     
pF1KSD WASSSSEANSRCQTPTKQKASPAPPQLCVVEAPSEPVEWTGAEESLFRVFHGTYFNNFCS
        .::::::::::::: :.: .  ::         : :::.::: :.:::. :::..:::.
NP_001 ETSSSSEANSRCQTPIKMKPNIEPP---------ENVEWSGAEASMFRVLIGTYYDNFCA
            410       420                430       440       450   

         460       470        480       490       500       510    
pF1KSD IARLLGTKTCKQVFQFAVKES-LILKLPTDELMNPSQKKKRKHRLWAAHCRKIQLKKDNS
       ::::.:::::.::..: :::: .:   :.... .: .:::::::::::::::::::::.:
NP_001 IARLIGTKTCRQVYEFRVKESSIIAPAPAEDVDTPPRKKKRKHRLWAAHCRKIQLKKDGS
           460       470       480       490       500       510   

          520       530       540       550       560       570    
pF1KSD STQVYNYQPCDHPDRPCDSTCPCIMTQNFCEKFCQCNPDCQNRFPGCRCKTQCNTKQCPC
       :..:::::::::: .::::.:::...::::::::::. .:::::::::::.:::::::::
NP_001 SNHVYNYQPCDHPRQPCDSSCPCVIAQNFCEKFCQCSSECQNRFPGCRCKAQCNTKQCPC
           520       530       540       550       560       570   

          580       590       600       610       620       630    
pF1KSD YLAVRECDPDLCLTCGASEHWDCKVVSCKNCSIQRGLKKHLLLAPSDVAGWGTFIKESVQ
       :::::::::::::::::..::: : ::::::::::: ::::::::::::::: :::. ::
NP_001 YLAVRECDPDLCLTCGAADHWDSKNVSCKNCSIQRGSKKHLLLAPSDVAGWGIFIKDPVQ
           580       590       600       610       620       630   

          640       650       660       670       680       690    
pF1KSD KNEFISEYCGELISQDEADRRGKVYDKYMSSFLFNLNNDFVVDATRKGNKIRFANHSVNP
       :::::::::::.::::::::::::::::: ::::::::::::::::::::::::::::::
NP_001 KNEFISEYCGEIISQDEADRRGKVYDKYMCSFLFNLNNDFVVDATRKGNKIRFANHSVNP
           640       650       660       670       680       690   

          700       710       720       730       740       
pF1KSD NCYAKVVMVNGDHRIGIFAKRAIQAGEELFFDYRYSQADALKYVGIERETDVL
       ::::::.:::::::::::::::::.:::::::::::::::::::::::: .. 
NP_001 NCYAKVMMVNGDHRIGIFAKRAIQTGEELFFDYRYSQADALKYVGIEREMEIP
           700       710       720       730       740      




747 residues in 1 query   sequences
60827320 residues in 85289 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Thu Nov  3 01:35:29 2016 done: Thu Nov  3 01:35:31 2016
 Total Scan time: 11.760 Total Display time:  0.200

Function used was FASTA [36.3.4 Apr, 2011]
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