Result of FASTA (omim) for pF1KA1568
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KA1568, 1378 aa
  1>>>pF1KA1568 1378 - 1378 aa - 1378 aa
Library: /omim/omim.rfq.tfa
  60827320 residues in 85289 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 10.2281+/-0.000493; mu= 0.2792+/- 0.031
 mean_var=396.3375+/-82.393, 0's: 0 Z-trim(120.0): 564  B-trim: 33 in 1/57
 Lambda= 0.064423
 statistics sampled from 33973 (34677) to 33973 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.717), E-opt: 0.2 (0.407), width:  16
 Scan time: 12.890

The best scores are:                                      opt bits E(85289)
NP_002933 (OMIM: 602431,610878) roundabout homolog (1378) 9310 881.4       0
NP_001276968 (OMIM: 602431,610878) roundabout homo (1382) 9292 879.7       0
XP_016862495 (OMIM: 602431,610878) PREDICTED: roun (1379) 9254 876.2       0
NP_001122401 (OMIM: 602431,610878) roundabout homo (1394) 9179 869.2       0
XP_016862492 (OMIM: 602431,610878) PREDICTED: roun (1401) 9179 869.2       0
XP_016862493 (OMIM: 602431,610878) PREDICTED: roun (1398) 9161 867.5       0
XP_011532287 (OMIM: 602431,610878) PREDICTED: roun (1405) 9161 867.5       0
XP_016862494 (OMIM: 602431,610878) PREDICTED: roun (1396) 9142 865.8       0
XP_016862490 (OMIM: 602431,610878) PREDICTED: roun (1403) 9142 865.8       0
XP_016862491 (OMIM: 602431,610878) PREDICTED: roun (1402) 9123 864.0       0
XP_016862482 (OMIM: 602431,610878) PREDICTED: roun (1469) 8893 842.7       0
XP_016862481 (OMIM: 602431,610878) PREDICTED: roun (1489) 8744 828.8       0
XP_016862480 (OMIM: 602431,610878) PREDICTED: roun (1496) 8744 828.8       0
NP_001276969 (OMIM: 602431,610878) roundabout homo (1443) 8471 803.4       0
XP_011532284 (OMIM: 602431,610878) PREDICTED: roun (1557) 8340 791.3       0
XP_016862476 (OMIM: 602431,610878) PREDICTED: roun (1554) 8323 789.7       0
XP_016862489 (OMIM: 602431,610878) PREDICTED: roun (1420) 7030 669.5 4.8e-191
XP_016862488 (OMIM: 602431,610878) PREDICTED: roun (1422) 7012 667.8 1.5e-190
XP_016862487 (OMIM: 602431,610878) PREDICTED: roun (1424) 7012 667.8 1.5e-190
XP_016862475 (OMIM: 602431,610878) PREDICTED: roun (1576) 7012 667.9 1.7e-190
XP_016862478 (OMIM: 602431,610878) PREDICTED: roun (1534) 6899 657.4 2.4e-187
XP_016862486 (OMIM: 602431,610878) PREDICTED: roun (1438) 6881 655.7 7.2e-187
XP_016862485 (OMIM: 602431,610878) PREDICTED: roun (1440) 6881 655.7 7.2e-187
XP_016862483 (OMIM: 602431,610878) PREDICTED: roun (1445) 6881 655.7 7.2e-187
XP_011532286 (OMIM: 602431,610878) PREDICTED: roun (1447) 6881 655.7 7.2e-187
XP_016862479 (OMIM: 602431,610878) PREDICTED: roun (1531) 6881 655.7 7.5e-187
XP_016862477 (OMIM: 602431,610878) PREDICTED: roun (1536) 6881 655.7 7.5e-187
XP_011532285 (OMIM: 602431,610878) PREDICTED: roun (1538) 6881 655.7 7.5e-187
XP_011532283 (OMIM: 602431,610878) PREDICTED: roun (1597) 6881 655.7 7.7e-187
XP_016862484 (OMIM: 602431,610878) PREDICTED: roun (1442) 6859 653.6  3e-186
NP_001276994 (OMIM: 602431,610878) roundabout homo ( 785) 5318 510.1 2.6e-143
NP_001139317 (OMIM: 602430) roundabout homolog 1 i (1551) 4138 400.7 4.2e-110
XP_011532282 (OMIM: 602430) PREDICTED: roundabout  (1590) 4137 400.7 4.6e-110
NP_598334 (OMIM: 602430) roundabout homolog 1 isof (1606) 4100 397.2  5e-109
XP_011532280 (OMIM: 602430) PREDICTED: roundabout  (1645) 4099 397.2 5.4e-109
XP_016862472 (OMIM: 602430) PREDICTED: roundabout  (1612) 4054 393.0 9.7e-108
NP_002932 (OMIM: 602430) roundabout homolog 1 isof (1651) 4053 392.9  1e-107
XP_016862471 (OMIM: 602430) PREDICTED: roundabout  (1626) 4041 391.8 2.2e-107
XP_006713340 (OMIM: 602430) PREDICTED: roundabout  (1615) 4033 391.0 3.7e-107
XP_016862473 (OMIM: 602430) PREDICTED: roundabout  (1596) 4032 390.9  4e-107
XP_011532279 (OMIM: 602430) PREDICTED: roundabout  (1654) 4032 390.9 4.1e-107
XP_011532278 (OMIM: 602430) PREDICTED: roundabout  (1654) 4032 390.9 4.1e-107
XP_011532281 (OMIM: 602430) PREDICTED: roundabout  (1599) 4017 389.5  1e-106
XP_016862474 (OMIM: 602430) PREDICTED: roundabout  (1535) 3612 351.9 2.2e-95
NP_071765 (OMIM: 607313,608630) roundabout homolog (1386) 3375 329.8 8.7e-89
XP_016873611 (OMIM: 607313,608630) PREDICTED: roun (1364) 3372 329.5   1e-88
XP_011524145 (OMIM: 114500,120470,133239,157600) P (1443)  648 76.3 1.8e-12
XP_016881057 (OMIM: 114500,120470,133239,157600) P (1445)  648 76.3 1.8e-12
NP_005206 (OMIM: 114500,120470,133239,157600) netr (1447)  648 76.3 1.8e-12
XP_016877726 (OMIM: 601907) PREDICTED: neogenin is (1394)  626 74.3 7.2e-12


>>NP_002933 (OMIM: 602431,610878) roundabout homolog 2 i  (1378 aa)
 initn: 9310 init1: 9310 opt: 9310  Z-score: 4696.2  bits: 881.4 E(85289):    0
Smith-Waterman score: 9310; 100.0% identity (100.0% similar) in 1378 aa overlap (1-1378:1-1378)

               10        20        30        40        50        60
pF1KA1 MSLLMFTQLLLCGFLYVRVDGSRLRQEDFPPRIVEHPSDVIVSKGEPTTLNCKAEGRPTP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 MSLLMFTQLLLCGFLYVRVDGSRLRQEDFPPRIVEHPSDVIVSKGEPTTLNCKAEGRPTP
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KA1 TIEWYKDGERVETDKDDPRSHRMLLPSGSLFFLRIVHGRRSKPDEGSYVCVARNYLGEAV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 TIEWYKDGERVETDKDDPRSHRMLLPSGSLFFLRIVHGRRSKPDEGSYVCVARNYLGEAV
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KA1 SRNASLEVALLRDDFRQNPTDVVVAAGEPAILECQPPRGHPEPTIYWKKDKVRIDDKEER
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 SRNASLEVALLRDDFRQNPTDVVVAAGEPAILECQPPRGHPEPTIYWKKDKVRIDDKEER
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KA1 ISIRGGKLMISNTRKSDAGMYTCVGTNMVGERDSDPAELTVFERPTFLRRPINQVVLEEE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 ISIRGGKLMISNTRKSDAGMYTCVGTNMVGERDSDPAELTVFERPTFLRRPINQVVLEEE
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KA1 AVEFRCQVQGDPQPTVRWKKDDADLPRGRYDIKDDYTLRIKKTMSTDEGTYMCIAENRVG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 AVEFRCQVQGDPQPTVRWKKDDADLPRGRYDIKDDYTLRIKKTMSTDEGTYMCIAENRVG
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KA1 KMEASATLTVRAPPQFVVRPRDQIVAQGRTVTFPCETKGNPQPAVFWQKEGSQNLLFPNQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 KMEASATLTVRAPPQFVVRPRDQIVAQGRTVTFPCETKGNPQPAVFWQKEGSQNLLFPNQ
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KA1 PQQPNSRCSVSPTGDLTITNIQRSDAGYYICQALTVAGSILAKAQLEVTDVLTDRPPPII
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 PQQPNSRCSVSPTGDLTITNIQRSDAGYYICQALTVAGSILAKAQLEVTDVLTDRPPPII
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KA1 LQGPANQTLAVDGTALLKCKATGDPLPVISWLKEGFTFPGRDPRATIQEQGTLQIKNLRI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 LQGPANQTLAVDGTALLKCKATGDPLPVISWLKEGFTFPGRDPRATIQEQGTLQIKNLRI
              430       440       450       460       470       480

              490       500       510       520       530       540
pF1KA1 SDTGTYTCVATSSSGETSWSAVLDVTESGATISKNYDLSDLPGPPSKPQVTDVTKNSVTL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 SDTGTYTCVATSSSGETSWSAVLDVTESGATISKNYDLSDLPGPPSKPQVTDVTKNSVTL
              490       500       510       520       530       540

              550       560       570       580       590       600
pF1KA1 SWQPGTPGTLPASAYIIEAFSQSVSNSWQTVANHVKTTLYTVRGLRPNTIYLFMVRAINP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 SWQPGTPGTLPASAYIIEAFSQSVSNSWQTVANHVKTTLYTVRGLRPNTIYLFMVRAINP
              550       560       570       580       590       600

              610       620       630       640       650       660
pF1KA1 QGLSDPSPMSDPVRTQDISPPAQGVDHRQVQKELGDVLVRLHNPVVLTPTTVQVTWTVDR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 QGLSDPSPMSDPVRTQDISPPAQGVDHRQVQKELGDVLVRLHNPVVLTPTTVQVTWTVDR
              610       620       630       640       650       660

              670       680       690       700       710       720
pF1KA1 QPQFIQGYRVMYRQTSGLQATSSWQNLDAKVPTERSAVLVNLKKGVTYEIKVRPYFNEFQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 QPQFIQGYRVMYRQTSGLQATSSWQNLDAKVPTERSAVLVNLKKGVTYEIKVRPYFNEFQ
              670       680       690       700       710       720

              730       740       750       760       770       780
pF1KA1 GMDSESKTVRTTEEAPSAPPQSVTVLTVGSYNSTSISVSWDPPPPDHQNGIIQEYKIWCL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 GMDSESKTVRTTEEAPSAPPQSVTVLTVGSYNSTSISVSWDPPPPDHQNGIIQEYKIWCL
              730       740       750       760       770       780

              790       800       810       820       830       840
pF1KA1 GNETRFHINKTVDAAIRSVIIGGLFPGIQYRVEVAASTSAGVGVKSEPQPIIIGRRNEVV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 GNETRFHINKTVDAAIRSVIIGGLFPGIQYRVEVAASTSAGVGVKSEPQPIIIGRRNEVV
              790       800       810       820       830       840

              850       860       870       880       890       900
pF1KA1 ITENNNSITEQITDVVKQPAFIAGIGGACWVILMGFSIWLYWRRKKRKGLSNYAVTFQRG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 ITENNNSITEQITDVVKQPAFIAGIGGACWVILMGFSIWLYWRRKKRKGLSNYAVTFQRG
              850       860       870       880       890       900

              910       920       930       940       950       960
pF1KA1 DGGLMSNGSRPGLLNAGDPSYPWLADSWPATSLPVNNSNSGPNEIGNFGRGDVLPPVPGQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 DGGLMSNGSRPGLLNAGDPSYPWLADSWPATSLPVNNSNSGPNEIGNFGRGDVLPPVPGQ
              910       920       930       940       950       960

              970       980       990      1000      1010      1020
pF1KA1 GDKTATMLSDGAIYSSIDFTTKTSYNSSSQITQATPYATTQILHSNSIHELAVDLPDPQW
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 GDKTATMLSDGAIYSSIDFTTKTSYNSSSQITQATPYATTQILHSNSIHELAVDLPDPQW
              970       980       990      1000      1010      1020

             1030      1040      1050      1060      1070      1080
pF1KA1 KSSIQQKTDLMGFGYSLPDQNKGNNGGKGGKKKKNKNSSKPQKNNGSTWANVPLPPPPVQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 KSSIQQKTDLMGFGYSLPDQNKGNNGGKGGKKKKNKNSSKPQKNNGSTWANVPLPPPPVQ
             1030      1040      1050      1060      1070      1080

             1090      1100      1110      1120      1130      1140
pF1KA1 PLPGTELEHYAVEQQENGYDSDSWCPPLPVQTYLHQGLEDELEEDDDRVPTPPVRGVASS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 PLPGTELEHYAVEQQENGYDSDSWCPPLPVQTYLHQGLEDELEEDDDRVPTPPVRGVASS
             1090      1100      1110      1120      1130      1140

             1150      1160      1170      1180      1190      1200
pF1KA1 PAISFGQQSTATLTPSPREEMQPMLQAHLDELTRAYQFDIAKQTWHIQSNNQPPQPPVPP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 PAISFGQQSTATLTPSPREEMQPMLQAHLDELTRAYQFDIAKQTWHIQSNNQPPQPPVPP
             1150      1160      1170      1180      1190      1200

             1210      1220      1230      1240      1250      1260
pF1KA1 LGYVSGALISDLETDVADDDADDEEEALEIPRPLRALDQTPGSSMDNLDSSVTGKAFTSS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 LGYVSGALISDLETDVADDDADDEEEALEIPRPLRALDQTPGSSMDNLDSSVTGKAFTSS
             1210      1220      1230      1240      1250      1260

             1270      1280      1290      1300      1310      1320
pF1KA1 QRPRPTSPFSTDSNTSAALSQSQRPRPTKKHKGGRMDQQPALPHRREGMTDEEALVPYSK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 QRPRPTSPFSTDSNTSAALSQSQRPRPTKKHKGGRMDQQPALPHRREGMTDEEALVPYSK
             1270      1280      1290      1300      1310      1320

             1330      1340      1350      1360      1370        
pF1KA1 PSFPSPGGHSSSGTASSKGSTGPRKTEVLRAGHQRNASDLLDIGYMGSNSQGQFTGEL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 PSFPSPGGHSSSGTASSKGSTGPRKTEVLRAGHQRNASDLLDIGYMGSNSQGQFTGEL
             1330      1340      1350      1360      1370        

>>NP_001276968 (OMIM: 602431,610878) roundabout homolog   (1382 aa)
 initn: 7201 init1: 7201 opt: 9292  Z-score: 4687.1  bits: 879.7 E(85289):    0
Smith-Waterman score: 9292; 99.7% identity (99.7% similar) in 1382 aa overlap (1-1378:1-1382)

               10        20        30        40        50        60
pF1KA1 MSLLMFTQLLLCGFLYVRVDGSRLRQEDFPPRIVEHPSDVIVSKGEPTTLNCKAEGRPTP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MSLLMFTQLLLCGFLYVRVDGSRLRQEDFPPRIVEHPSDVIVSKGEPTTLNCKAEGRPTP
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KA1 TIEWYKDGERVETDKDDPRSHRMLLPSGSLFFLRIVHGRRSKPDEGSYVCVARNYLGEAV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TIEWYKDGERVETDKDDPRSHRMLLPSGSLFFLRIVHGRRSKPDEGSYVCVARNYLGEAV
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KA1 SRNASLEVALLRDDFRQNPTDVVVAAGEPAILECQPPRGHPEPTIYWKKDKVRIDDKEER
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SRNASLEVALLRDDFRQNPTDVVVAAGEPAILECQPPRGHPEPTIYWKKDKVRIDDKEER
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KA1 ISIRGGKLMISNTRKSDAGMYTCVGTNMVGERDSDPAELTVFERPTFLRRPINQVVLEEE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ISIRGGKLMISNTRKSDAGMYTCVGTNMVGERDSDPAELTVFERPTFLRRPINQVVLEEE
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KA1 AVEFRCQVQGDPQPTVRWKKDDADLPRGRYDIKDDYTLRIKKTMSTDEGTYMCIAENRVG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AVEFRCQVQGDPQPTVRWKKDDADLPRGRYDIKDDYTLRIKKTMSTDEGTYMCIAENRVG
              250       260       270       280       290       300

              310           320       330       340       350      
pF1KA1 KMEASATLTVRA----PPQFVVRPRDQIVAQGRTVTFPCETKGNPQPAVFWQKEGSQNLL
       ::::::::::::    ::::::::::::::::::::::::::::::::::::::::::::
NP_001 KMEASATLTVRARPVAPPQFVVRPRDQIVAQGRTVTFPCETKGNPQPAVFWQKEGSQNLL
              310       320       330       340       350       360

        360       370       380       390       400       410      
pF1KA1 FPNQPQQPNSRCSVSPTGDLTITNIQRSDAGYYICQALTVAGSILAKAQLEVTDVLTDRP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FPNQPQQPNSRCSVSPTGDLTITNIQRSDAGYYICQALTVAGSILAKAQLEVTDVLTDRP
              370       380       390       400       410       420

        420       430       440       450       460       470      
pF1KA1 PPIILQGPANQTLAVDGTALLKCKATGDPLPVISWLKEGFTFPGRDPRATIQEQGTLQIK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PPIILQGPANQTLAVDGTALLKCKATGDPLPVISWLKEGFTFPGRDPRATIQEQGTLQIK
              430       440       450       460       470       480

        480       490       500       510       520       530      
pF1KA1 NLRISDTGTYTCVATSSSGETSWSAVLDVTESGATISKNYDLSDLPGPPSKPQVTDVTKN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NLRISDTGTYTCVATSSSGETSWSAVLDVTESGATISKNYDLSDLPGPPSKPQVTDVTKN
              490       500       510       520       530       540

        540       550       560       570       580       590      
pF1KA1 SVTLSWQPGTPGTLPASAYIIEAFSQSVSNSWQTVANHVKTTLYTVRGLRPNTIYLFMVR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SVTLSWQPGTPGTLPASAYIIEAFSQSVSNSWQTVANHVKTTLYTVRGLRPNTIYLFMVR
              550       560       570       580       590       600

        600       610       620       630       640       650      
pF1KA1 AINPQGLSDPSPMSDPVRTQDISPPAQGVDHRQVQKELGDVLVRLHNPVVLTPTTVQVTW
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AINPQGLSDPSPMSDPVRTQDISPPAQGVDHRQVQKELGDVLVRLHNPVVLTPTTVQVTW
              610       620       630       640       650       660

        660       670       680       690       700       710      
pF1KA1 TVDRQPQFIQGYRVMYRQTSGLQATSSWQNLDAKVPTERSAVLVNLKKGVTYEIKVRPYF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TVDRQPQFIQGYRVMYRQTSGLQATSSWQNLDAKVPTERSAVLVNLKKGVTYEIKVRPYF
              670       680       690       700       710       720

        720       730       740       750       760       770      
pF1KA1 NEFQGMDSESKTVRTTEEAPSAPPQSVTVLTVGSYNSTSISVSWDPPPPDHQNGIIQEYK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NEFQGMDSESKTVRTTEEAPSAPPQSVTVLTVGSYNSTSISVSWDPPPPDHQNGIIQEYK
              730       740       750       760       770       780

        780       790       800       810       820       830      
pF1KA1 IWCLGNETRFHINKTVDAAIRSVIIGGLFPGIQYRVEVAASTSAGVGVKSEPQPIIIGRR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IWCLGNETRFHINKTVDAAIRSVIIGGLFPGIQYRVEVAASTSAGVGVKSEPQPIIIGRR
              790       800       810       820       830       840

        840       850       860       870       880       890      
pF1KA1 NEVVITENNNSITEQITDVVKQPAFIAGIGGACWVILMGFSIWLYWRRKKRKGLSNYAVT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NEVVITENNNSITEQITDVVKQPAFIAGIGGACWVILMGFSIWLYWRRKKRKGLSNYAVT
              850       860       870       880       890       900

        900       910       920       930       940       950      
pF1KA1 FQRGDGGLMSNGSRPGLLNAGDPSYPWLADSWPATSLPVNNSNSGPNEIGNFGRGDVLPP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FQRGDGGLMSNGSRPGLLNAGDPSYPWLADSWPATSLPVNNSNSGPNEIGNFGRGDVLPP
              910       920       930       940       950       960

        960       970       980       990      1000      1010      
pF1KA1 VPGQGDKTATMLSDGAIYSSIDFTTKTSYNSSSQITQATPYATTQILHSNSIHELAVDLP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VPGQGDKTATMLSDGAIYSSIDFTTKTSYNSSSQITQATPYATTQILHSNSIHELAVDLP
              970       980       990      1000      1010      1020

       1020      1030      1040      1050      1060      1070      
pF1KA1 DPQWKSSIQQKTDLMGFGYSLPDQNKGNNGGKGGKKKKNKNSSKPQKNNGSTWANVPLPP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DPQWKSSIQQKTDLMGFGYSLPDQNKGNNGGKGGKKKKNKNSSKPQKNNGSTWANVPLPP
             1030      1040      1050      1060      1070      1080

       1080      1090      1100      1110      1120      1130      
pF1KA1 PPVQPLPGTELEHYAVEQQENGYDSDSWCPPLPVQTYLHQGLEDELEEDDDRVPTPPVRG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PPVQPLPGTELEHYAVEQQENGYDSDSWCPPLPVQTYLHQGLEDELEEDDDRVPTPPVRG
             1090      1100      1110      1120      1130      1140

       1140      1150      1160      1170      1180      1190      
pF1KA1 VASSPAISFGQQSTATLTPSPREEMQPMLQAHLDELTRAYQFDIAKQTWHIQSNNQPPQP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VASSPAISFGQQSTATLTPSPREEMQPMLQAHLDELTRAYQFDIAKQTWHIQSNNQPPQP
             1150      1160      1170      1180      1190      1200

       1200      1210      1220      1230      1240      1250      
pF1KA1 PVPPLGYVSGALISDLETDVADDDADDEEEALEIPRPLRALDQTPGSSMDNLDSSVTGKA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PVPPLGYVSGALISDLETDVADDDADDEEEALEIPRPLRALDQTPGSSMDNLDSSVTGKA
             1210      1220      1230      1240      1250      1260

       1260      1270      1280      1290      1300      1310      
pF1KA1 FTSSQRPRPTSPFSTDSNTSAALSQSQRPRPTKKHKGGRMDQQPALPHRREGMTDEEALV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FTSSQRPRPTSPFSTDSNTSAALSQSQRPRPTKKHKGGRMDQQPALPHRREGMTDEEALV
             1270      1280      1290      1300      1310      1320

       1320      1330      1340      1350      1360      1370      
pF1KA1 PYSKPSFPSPGGHSSSGTASSKGSTGPRKTEVLRAGHQRNASDLLDIGYMGSNSQGQFTG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PYSKPSFPSPGGHSSSGTASSKGSTGPRKTEVLRAGHQRNASDLLDIGYMGSNSQGQFTG
             1330      1340      1350      1360      1370      1380

         
pF1KA1 EL
       ::
NP_001 EL
         

>>XP_016862495 (OMIM: 602431,610878) PREDICTED: roundabo  (1379 aa)
 initn: 5001 init1: 4950 opt: 9254  Z-score: 4668.1  bits: 876.2 E(85289):    0
Smith-Waterman score: 9254; 99.5% identity (99.5% similar) in 1382 aa overlap (1-1378:1-1379)

               10        20        30        40        50        60
pF1KA1 MSLLMFTQLLLCGFLYVRVDGSRLRQEDFPPRIVEHPSDVIVSKGEPTTLNCKAEGRPTP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MSLLMFTQLLLCGFLYVRVDGSRLRQEDFPPRIVEHPSDVIVSKGEPTTLNCKAEGRPTP
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KA1 TIEWYKDGERVETDKDDPRSHRMLLPSGSLFFLRIVHGRRSKPDEGSYVCVARNYLGEAV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TIEWYKDGERVETDKDDPRSHRMLLPSGSLFFLRIVHGRRSKPDEGSYVCVARNYLGEAV
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KA1 SRNASLEVALLRDDFRQNPTDVVVAAGEPAILECQPPRGHPEPTIYWKKDKVRIDDKEER
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SRNASLEVALLRDDFRQNPTDVVVAAGEPAILECQPPRGHPEPTIYWKKDKVRIDDKEER
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KA1 ISIRGGKLMISNTRKSDAGMYTCVGTNMVGERDSDPAELTVFERPTFLRRPINQVVLEEE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ISIRGGKLMISNTRKSDAGMYTCVGTNMVGERDSDPAELTVFERPTFLRRPINQVVLEEE
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KA1 AVEFRCQVQGDPQPTVRWKKDDADLPRGRYDIKDDYTLRIKKTMSTDEGTYMCIAENRVG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AVEFRCQVQGDPQPTVRWKKDDADLPRGRYDIKDDYTLRIKKTMSTDEGTYMCIAENRVG
              250       260       270       280       290       300

              310           320       330       340       350      
pF1KA1 KMEASATLTVRA----PPQFVVRPRDQIVAQGRTVTFPCETKGNPQPAVFWQKEGSQNLL
       ::::::::::::    ::::::::::::::::::::::::::::::::::::::::::::
XP_016 KMEASATLTVRARPVAPPQFVVRPRDQIVAQGRTVTFPCETKGNPQPAVFWQKEGSQNLL
              310       320       330       340       350       360

        360       370       380       390       400       410      
pF1KA1 FPNQPQQPNSRCSVSPTGDLTITNIQRSDAGYYICQALTVAGSILAKAQLEVTDVLTDRP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FPNQPQQPNSRCSVSPTGDLTITNIQRSDAGYYICQALTVAGSILAKAQLEVTDVLTDRP
              370       380       390       400       410       420

        420       430       440       450       460       470      
pF1KA1 PPIILQGPANQTLAVDGTALLKCKATGDPLPVISWLKEGFTFPGRDPRATIQEQGTLQIK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PPIILQGPANQTLAVDGTALLKCKATGDPLPVISWLKEGFTFPGRDPRATIQEQGTLQIK
              430       440       450       460       470       480

        480       490       500       510       520       530      
pF1KA1 NLRISDTGTYTCVATSSSGETSWSAVLDVTESGATISKNYDLSDLPGPPSKPQVTDVTKN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NLRISDTGTYTCVATSSSGETSWSAVLDVTESGATISKNYDLSDLPGPPSKPQVTDVTKN
              490       500       510       520       530       540

        540       550       560       570       580       590      
pF1KA1 SVTLSWQPGTPGTLPASAYIIEAFSQSVSNSWQTVANHVKTTLYTVRGLRPNTIYLFMVR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SVTLSWQPGTPGTLPASAYIIEAFSQSVSNSWQTVANHVKTTLYTVRGLRPNTIYLFMVR
              550       560       570       580       590       600

        600       610       620       630       640       650      
pF1KA1 AINPQGLSDPSPMSDPVRTQDISPPAQGVDHRQVQKELGDVLVRLHNPVVLTPTTVQVTW
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AINPQGLSDPSPMSDPVRTQDISPPAQGVDHRQVQKELGDVLVRLHNPVVLTPTTVQVTW
              610       620       630       640       650       660

        660       670       680       690       700       710      
pF1KA1 TVDRQPQFIQGYRVMYRQTSGLQATSSWQNLDAKVPTERSAVLVNLKKGVTYEIKVRPYF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TVDRQPQFIQGYRVMYRQTSGLQATSSWQNLDAKVPTERSAVLVNLKKGVTYEIKVRPYF
              670       680       690       700       710       720

        720       730       740       750       760       770      
pF1KA1 NEFQGMDSESKTVRTTEEAPSAPPQSVTVLTVGSYNSTSISVSWDPPPPDHQNGIIQEYK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NEFQGMDSESKTVRTTEEAPSAPPQSVTVLTVGSYNSTSISVSWDPPPPDHQNGIIQEYK
              730       740       750       760       770       780

        780       790       800       810       820       830      
pF1KA1 IWCLGNETRFHINKTVDAAIRSVIIGGLFPGIQYRVEVAASTSAGVGVKSEPQPIIIGRR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IWCLGNETRFHINKTVDAAIRSVIIGGLFPGIQYRVEVAASTSAGVGVKSEPQPIIIGRR
              790       800       810       820       830       840

        840       850       860       870       880       890      
pF1KA1 NEVVITENNNSITEQITDVVKQPAFIAGIGGACWVILMGFSIWLYWRRKKRKGLSNYAVT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NEVVITENNNSITEQITDVVKQPAFIAGIGGACWVILMGFSIWLYWRRKKRKGLSNYAVT
              850       860       870       880       890       900

        900       910       920       930       940       950      
pF1KA1 FQRGDGGLMSNGSRPGLLNAGDPSYPWLADSWPATSLPVNNSNSGPNEIGNFGRGDVLPP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FQRGDGGLMSNGSRPGLLNAGDPSYPWLADSWPATSLPVNNSNSGPNEIGNFGRGDVLPP
              910       920       930       940       950       960

        960       970       980       990      1000      1010      
pF1KA1 VPGQGDKTATMLSDGAIYSSIDFTTKTSYNSSSQITQATPYATTQILHSNSIHELAVDLP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VPGQGDKTATMLSDGAIYSSIDFTTKTSYNSSSQITQATPYATTQILHSNSIHELAVDLP
              970       980       990      1000      1010      1020

       1020      1030      1040      1050      1060      1070      
pF1KA1 DPQWKSSIQQKTDLMGFGYSLPDQNKGNNGGKGGKKKKNKNSSKPQKNNGSTWANVPLPP
       :::::::::::::::::::::::::::   ::::::::::::::::::::::::::::::
XP_016 DPQWKSSIQQKTDLMGFGYSLPDQNKG---GKGGKKKKNKNSSKPQKNNGSTWANVPLPP
             1030      1040         1050      1060      1070       

       1080      1090      1100      1110      1120      1130      
pF1KA1 PPVQPLPGTELEHYAVEQQENGYDSDSWCPPLPVQTYLHQGLEDELEEDDDRVPTPPVRG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PPVQPLPGTELEHYAVEQQENGYDSDSWCPPLPVQTYLHQGLEDELEEDDDRVPTPPVRG
      1080      1090      1100      1110      1120      1130       

       1140      1150      1160      1170      1180      1190      
pF1KA1 VASSPAISFGQQSTATLTPSPREEMQPMLQAHLDELTRAYQFDIAKQTWHIQSNNQPPQP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VASSPAISFGQQSTATLTPSPREEMQPMLQAHLDELTRAYQFDIAKQTWHIQSNNQPPQP
      1140      1150      1160      1170      1180      1190       

       1200      1210      1220      1230      1240      1250      
pF1KA1 PVPPLGYVSGALISDLETDVADDDADDEEEALEIPRPLRALDQTPGSSMDNLDSSVTGKA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PVPPLGYVSGALISDLETDVADDDADDEEEALEIPRPLRALDQTPGSSMDNLDSSVTGKA
      1200      1210      1220      1230      1240      1250       

       1260      1270      1280      1290      1300      1310      
pF1KA1 FTSSQRPRPTSPFSTDSNTSAALSQSQRPRPTKKHKGGRMDQQPALPHRREGMTDEEALV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FTSSQRPRPTSPFSTDSNTSAALSQSQRPRPTKKHKGGRMDQQPALPHRREGMTDEEALV
      1260      1270      1280      1290      1300      1310       

       1320      1330      1340      1350      1360      1370      
pF1KA1 PYSKPSFPSPGGHSSSGTASSKGSTGPRKTEVLRAGHQRNASDLLDIGYMGSNSQGQFTG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PYSKPSFPSPGGHSSSGTASSKGSTGPRKTEVLRAGHQRNASDLLDIGYMGSNSQGQFTG
      1320      1330      1340      1350      1360      1370       

         
pF1KA1 EL
       ::
XP_016 EL
         

>>NP_001122401 (OMIM: 602431,610878) roundabout homolog   (1394 aa)
 initn: 9179 init1: 9179 opt: 9179  Z-score: 4630.3  bits: 869.2 E(85289):    0
Smith-Waterman score: 9179; 100.0% identity (100.0% similar) in 1358 aa overlap (21-1378:37-1394)

                         10        20        30        40        50
pF1KA1           MSLLMFTQLLLCGFLYVRVDGSRLRQEDFPPRIVEHPSDVIVSKGEPTTL
                                     ::::::::::::::::::::::::::::::
NP_001 RVTRRMWTWAPGLLMMTVVFWGHQGNGQGQGSRLRQEDFPPRIVEHPSDVIVSKGEPTTL
         10        20        30        40        50        60      

               60        70        80        90       100       110
pF1KA1 NCKAEGRPTPTIEWYKDGERVETDKDDPRSHRMLLPSGSLFFLRIVHGRRSKPDEGSYVC
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NCKAEGRPTPTIEWYKDGERVETDKDDPRSHRMLLPSGSLFFLRIVHGRRSKPDEGSYVC
         70        80        90       100       110       120      

              120       130       140       150       160       170
pF1KA1 VARNYLGEAVSRNASLEVALLRDDFRQNPTDVVVAAGEPAILECQPPRGHPEPTIYWKKD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VARNYLGEAVSRNASLEVALLRDDFRQNPTDVVVAAGEPAILECQPPRGHPEPTIYWKKD
        130       140       150       160       170       180      

              180       190       200       210       220       230
pF1KA1 KVRIDDKEERISIRGGKLMISNTRKSDAGMYTCVGTNMVGERDSDPAELTVFERPTFLRR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KVRIDDKEERISIRGGKLMISNTRKSDAGMYTCVGTNMVGERDSDPAELTVFERPTFLRR
        190       200       210       220       230       240      

              240       250       260       270       280       290
pF1KA1 PINQVVLEEEAVEFRCQVQGDPQPTVRWKKDDADLPRGRYDIKDDYTLRIKKTMSTDEGT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PINQVVLEEEAVEFRCQVQGDPQPTVRWKKDDADLPRGRYDIKDDYTLRIKKTMSTDEGT
        250       260       270       280       290       300      

              300       310       320       330       340       350
pF1KA1 YMCIAENRVGKMEASATLTVRAPPQFVVRPRDQIVAQGRTVTFPCETKGNPQPAVFWQKE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 YMCIAENRVGKMEASATLTVRAPPQFVVRPRDQIVAQGRTVTFPCETKGNPQPAVFWQKE
        310       320       330       340       350       360      

              360       370       380       390       400       410
pF1KA1 GSQNLLFPNQPQQPNSRCSVSPTGDLTITNIQRSDAGYYICQALTVAGSILAKAQLEVTD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GSQNLLFPNQPQQPNSRCSVSPTGDLTITNIQRSDAGYYICQALTVAGSILAKAQLEVTD
        370       380       390       400       410       420      

              420       430       440       450       460       470
pF1KA1 VLTDRPPPIILQGPANQTLAVDGTALLKCKATGDPLPVISWLKEGFTFPGRDPRATIQEQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VLTDRPPPIILQGPANQTLAVDGTALLKCKATGDPLPVISWLKEGFTFPGRDPRATIQEQ
        430       440       450       460       470       480      

              480       490       500       510       520       530
pF1KA1 GTLQIKNLRISDTGTYTCVATSSSGETSWSAVLDVTESGATISKNYDLSDLPGPPSKPQV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GTLQIKNLRISDTGTYTCVATSSSGETSWSAVLDVTESGATISKNYDLSDLPGPPSKPQV
        490       500       510       520       530       540      

              540       550       560       570       580       590
pF1KA1 TDVTKNSVTLSWQPGTPGTLPASAYIIEAFSQSVSNSWQTVANHVKTTLYTVRGLRPNTI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TDVTKNSVTLSWQPGTPGTLPASAYIIEAFSQSVSNSWQTVANHVKTTLYTVRGLRPNTI
        550       560       570       580       590       600      

              600       610       620       630       640       650
pF1KA1 YLFMVRAINPQGLSDPSPMSDPVRTQDISPPAQGVDHRQVQKELGDVLVRLHNPVVLTPT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 YLFMVRAINPQGLSDPSPMSDPVRTQDISPPAQGVDHRQVQKELGDVLVRLHNPVVLTPT
        610       620       630       640       650       660      

              660       670       680       690       700       710
pF1KA1 TVQVTWTVDRQPQFIQGYRVMYRQTSGLQATSSWQNLDAKVPTERSAVLVNLKKGVTYEI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TVQVTWTVDRQPQFIQGYRVMYRQTSGLQATSSWQNLDAKVPTERSAVLVNLKKGVTYEI
        670       680       690       700       710       720      

              720       730       740       750       760       770
pF1KA1 KVRPYFNEFQGMDSESKTVRTTEEAPSAPPQSVTVLTVGSYNSTSISVSWDPPPPDHQNG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KVRPYFNEFQGMDSESKTVRTTEEAPSAPPQSVTVLTVGSYNSTSISVSWDPPPPDHQNG
        730       740       750       760       770       780      

              780       790       800       810       820       830
pF1KA1 IIQEYKIWCLGNETRFHINKTVDAAIRSVIIGGLFPGIQYRVEVAASTSAGVGVKSEPQP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IIQEYKIWCLGNETRFHINKTVDAAIRSVIIGGLFPGIQYRVEVAASTSAGVGVKSEPQP
        790       800       810       820       830       840      

              840       850       860       870       880       890
pF1KA1 IIIGRRNEVVITENNNSITEQITDVVKQPAFIAGIGGACWVILMGFSIWLYWRRKKRKGL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IIIGRRNEVVITENNNSITEQITDVVKQPAFIAGIGGACWVILMGFSIWLYWRRKKRKGL
        850       860       870       880       890       900      

              900       910       920       930       940       950
pF1KA1 SNYAVTFQRGDGGLMSNGSRPGLLNAGDPSYPWLADSWPATSLPVNNSNSGPNEIGNFGR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SNYAVTFQRGDGGLMSNGSRPGLLNAGDPSYPWLADSWPATSLPVNNSNSGPNEIGNFGR
        910       920       930       940       950       960      

              960       970       980       990      1000      1010
pF1KA1 GDVLPPVPGQGDKTATMLSDGAIYSSIDFTTKTSYNSSSQITQATPYATTQILHSNSIHE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GDVLPPVPGQGDKTATMLSDGAIYSSIDFTTKTSYNSSSQITQATPYATTQILHSNSIHE
        970       980       990      1000      1010      1020      

             1020      1030      1040      1050      1060      1070
pF1KA1 LAVDLPDPQWKSSIQQKTDLMGFGYSLPDQNKGNNGGKGGKKKKNKNSSKPQKNNGSTWA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LAVDLPDPQWKSSIQQKTDLMGFGYSLPDQNKGNNGGKGGKKKKNKNSSKPQKNNGSTWA
       1030      1040      1050      1060      1070      1080      

             1080      1090      1100      1110      1120      1130
pF1KA1 NVPLPPPPVQPLPGTELEHYAVEQQENGYDSDSWCPPLPVQTYLHQGLEDELEEDDDRVP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NVPLPPPPVQPLPGTELEHYAVEQQENGYDSDSWCPPLPVQTYLHQGLEDELEEDDDRVP
       1090      1100      1110      1120      1130      1140      

             1140      1150      1160      1170      1180      1190
pF1KA1 TPPVRGVASSPAISFGQQSTATLTPSPREEMQPMLQAHLDELTRAYQFDIAKQTWHIQSN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TPPVRGVASSPAISFGQQSTATLTPSPREEMQPMLQAHLDELTRAYQFDIAKQTWHIQSN
       1150      1160      1170      1180      1190      1200      

             1200      1210      1220      1230      1240      1250
pF1KA1 NQPPQPPVPPLGYVSGALISDLETDVADDDADDEEEALEIPRPLRALDQTPGSSMDNLDS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NQPPQPPVPPLGYVSGALISDLETDVADDDADDEEEALEIPRPLRALDQTPGSSMDNLDS
       1210      1220      1230      1240      1250      1260      

             1260      1270      1280      1290      1300      1310
pF1KA1 SVTGKAFTSSQRPRPTSPFSTDSNTSAALSQSQRPRPTKKHKGGRMDQQPALPHRREGMT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SVTGKAFTSSQRPRPTSPFSTDSNTSAALSQSQRPRPTKKHKGGRMDQQPALPHRREGMT
       1270      1280      1290      1300      1310      1320      

             1320      1330      1340      1350      1360      1370
pF1KA1 DEEALVPYSKPSFPSPGGHSSSGTASSKGSTGPRKTEVLRAGHQRNASDLLDIGYMGSNS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DEEALVPYSKPSFPSPGGHSSSGTASSKGSTGPRKTEVLRAGHQRNASDLLDIGYMGSNS
       1330      1340      1350      1360      1370      1380      

               
pF1KA1 QGQFTGEL
       ::::::::
NP_001 QGQFTGEL
       1390    

>>XP_016862492 (OMIM: 602431,610878) PREDICTED: roundabo  (1401 aa)
 initn: 9179 init1: 9179 opt: 9179  Z-score: 4630.3  bits: 869.2 E(85289):    0
Smith-Waterman score: 9179; 100.0% identity (100.0% similar) in 1358 aa overlap (21-1378:44-1401)

                         10        20        30        40        50
pF1KA1           MSLLMFTQLLLCGFLYVRVDGSRLRQEDFPPRIVEHPSDVIVSKGEPTTL
                                     ::::::::::::::::::::::::::::::
XP_016 ELLFVLMLFLSGPTLSKLTRTPWKGKPWKGGSRLRQEDFPPRIVEHPSDVIVSKGEPTTL
            20        30        40        50        60        70   

               60        70        80        90       100       110
pF1KA1 NCKAEGRPTPTIEWYKDGERVETDKDDPRSHRMLLPSGSLFFLRIVHGRRSKPDEGSYVC
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NCKAEGRPTPTIEWYKDGERVETDKDDPRSHRMLLPSGSLFFLRIVHGRRSKPDEGSYVC
            80        90       100       110       120       130   

              120       130       140       150       160       170
pF1KA1 VARNYLGEAVSRNASLEVALLRDDFRQNPTDVVVAAGEPAILECQPPRGHPEPTIYWKKD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VARNYLGEAVSRNASLEVALLRDDFRQNPTDVVVAAGEPAILECQPPRGHPEPTIYWKKD
           140       150       160       170       180       190   

              180       190       200       210       220       230
pF1KA1 KVRIDDKEERISIRGGKLMISNTRKSDAGMYTCVGTNMVGERDSDPAELTVFERPTFLRR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KVRIDDKEERISIRGGKLMISNTRKSDAGMYTCVGTNMVGERDSDPAELTVFERPTFLRR
           200       210       220       230       240       250   

              240       250       260       270       280       290
pF1KA1 PINQVVLEEEAVEFRCQVQGDPQPTVRWKKDDADLPRGRYDIKDDYTLRIKKTMSTDEGT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PINQVVLEEEAVEFRCQVQGDPQPTVRWKKDDADLPRGRYDIKDDYTLRIKKTMSTDEGT
           260       270       280       290       300       310   

              300       310       320       330       340       350
pF1KA1 YMCIAENRVGKMEASATLTVRAPPQFVVRPRDQIVAQGRTVTFPCETKGNPQPAVFWQKE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 YMCIAENRVGKMEASATLTVRAPPQFVVRPRDQIVAQGRTVTFPCETKGNPQPAVFWQKE
           320       330       340       350       360       370   

              360       370       380       390       400       410
pF1KA1 GSQNLLFPNQPQQPNSRCSVSPTGDLTITNIQRSDAGYYICQALTVAGSILAKAQLEVTD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GSQNLLFPNQPQQPNSRCSVSPTGDLTITNIQRSDAGYYICQALTVAGSILAKAQLEVTD
           380       390       400       410       420       430   

              420       430       440       450       460       470
pF1KA1 VLTDRPPPIILQGPANQTLAVDGTALLKCKATGDPLPVISWLKEGFTFPGRDPRATIQEQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VLTDRPPPIILQGPANQTLAVDGTALLKCKATGDPLPVISWLKEGFTFPGRDPRATIQEQ
           440       450       460       470       480       490   

              480       490       500       510       520       530
pF1KA1 GTLQIKNLRISDTGTYTCVATSSSGETSWSAVLDVTESGATISKNYDLSDLPGPPSKPQV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GTLQIKNLRISDTGTYTCVATSSSGETSWSAVLDVTESGATISKNYDLSDLPGPPSKPQV
           500       510       520       530       540       550   

              540       550       560       570       580       590
pF1KA1 TDVTKNSVTLSWQPGTPGTLPASAYIIEAFSQSVSNSWQTVANHVKTTLYTVRGLRPNTI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TDVTKNSVTLSWQPGTPGTLPASAYIIEAFSQSVSNSWQTVANHVKTTLYTVRGLRPNTI
           560       570       580       590       600       610   

              600       610       620       630       640       650
pF1KA1 YLFMVRAINPQGLSDPSPMSDPVRTQDISPPAQGVDHRQVQKELGDVLVRLHNPVVLTPT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 YLFMVRAINPQGLSDPSPMSDPVRTQDISPPAQGVDHRQVQKELGDVLVRLHNPVVLTPT
           620       630       640       650       660       670   

              660       670       680       690       700       710
pF1KA1 TVQVTWTVDRQPQFIQGYRVMYRQTSGLQATSSWQNLDAKVPTERSAVLVNLKKGVTYEI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TVQVTWTVDRQPQFIQGYRVMYRQTSGLQATSSWQNLDAKVPTERSAVLVNLKKGVTYEI
           680       690       700       710       720       730   

              720       730       740       750       760       770
pF1KA1 KVRPYFNEFQGMDSESKTVRTTEEAPSAPPQSVTVLTVGSYNSTSISVSWDPPPPDHQNG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KVRPYFNEFQGMDSESKTVRTTEEAPSAPPQSVTVLTVGSYNSTSISVSWDPPPPDHQNG
           740       750       760       770       780       790   

              780       790       800       810       820       830
pF1KA1 IIQEYKIWCLGNETRFHINKTVDAAIRSVIIGGLFPGIQYRVEVAASTSAGVGVKSEPQP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IIQEYKIWCLGNETRFHINKTVDAAIRSVIIGGLFPGIQYRVEVAASTSAGVGVKSEPQP
           800       810       820       830       840       850   

              840       850       860       870       880       890
pF1KA1 IIIGRRNEVVITENNNSITEQITDVVKQPAFIAGIGGACWVILMGFSIWLYWRRKKRKGL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IIIGRRNEVVITENNNSITEQITDVVKQPAFIAGIGGACWVILMGFSIWLYWRRKKRKGL
           860       870       880       890       900       910   

              900       910       920       930       940       950
pF1KA1 SNYAVTFQRGDGGLMSNGSRPGLLNAGDPSYPWLADSWPATSLPVNNSNSGPNEIGNFGR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SNYAVTFQRGDGGLMSNGSRPGLLNAGDPSYPWLADSWPATSLPVNNSNSGPNEIGNFGR
           920       930       940       950       960       970   

              960       970       980       990      1000      1010
pF1KA1 GDVLPPVPGQGDKTATMLSDGAIYSSIDFTTKTSYNSSSQITQATPYATTQILHSNSIHE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GDVLPPVPGQGDKTATMLSDGAIYSSIDFTTKTSYNSSSQITQATPYATTQILHSNSIHE
           980       990      1000      1010      1020      1030   

             1020      1030      1040      1050      1060      1070
pF1KA1 LAVDLPDPQWKSSIQQKTDLMGFGYSLPDQNKGNNGGKGGKKKKNKNSSKPQKNNGSTWA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LAVDLPDPQWKSSIQQKTDLMGFGYSLPDQNKGNNGGKGGKKKKNKNSSKPQKNNGSTWA
          1040      1050      1060      1070      1080      1090   

             1080      1090      1100      1110      1120      1130
pF1KA1 NVPLPPPPVQPLPGTELEHYAVEQQENGYDSDSWCPPLPVQTYLHQGLEDELEEDDDRVP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NVPLPPPPVQPLPGTELEHYAVEQQENGYDSDSWCPPLPVQTYLHQGLEDELEEDDDRVP
          1100      1110      1120      1130      1140      1150   

             1140      1150      1160      1170      1180      1190
pF1KA1 TPPVRGVASSPAISFGQQSTATLTPSPREEMQPMLQAHLDELTRAYQFDIAKQTWHIQSN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TPPVRGVASSPAISFGQQSTATLTPSPREEMQPMLQAHLDELTRAYQFDIAKQTWHIQSN
          1160      1170      1180      1190      1200      1210   

             1200      1210      1220      1230      1240      1250
pF1KA1 NQPPQPPVPPLGYVSGALISDLETDVADDDADDEEEALEIPRPLRALDQTPGSSMDNLDS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NQPPQPPVPPLGYVSGALISDLETDVADDDADDEEEALEIPRPLRALDQTPGSSMDNLDS
          1220      1230      1240      1250      1260      1270   

             1260      1270      1280      1290      1300      1310
pF1KA1 SVTGKAFTSSQRPRPTSPFSTDSNTSAALSQSQRPRPTKKHKGGRMDQQPALPHRREGMT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SVTGKAFTSSQRPRPTSPFSTDSNTSAALSQSQRPRPTKKHKGGRMDQQPALPHRREGMT
          1280      1290      1300      1310      1320      1330   

             1320      1330      1340      1350      1360      1370
pF1KA1 DEEALVPYSKPSFPSPGGHSSSGTASSKGSTGPRKTEVLRAGHQRNASDLLDIGYMGSNS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DEEALVPYSKPSFPSPGGHSSSGTASSKGSTGPRKTEVLRAGHQRNASDLLDIGYMGSNS
          1340      1350      1360      1370      1380      1390   

               
pF1KA1 QGQFTGEL
       ::::::::
XP_016 QGQFTGEL
          1400 

>>XP_016862493 (OMIM: 602431,610878) PREDICTED: roundabo  (1398 aa)
 initn: 7201 init1: 7201 opt: 9161  Z-score: 4621.3  bits: 867.5 E(85289):    0
Smith-Waterman score: 9161; 99.7% identity (99.7% similar) in 1362 aa overlap (21-1378:37-1398)

                         10        20        30        40        50
pF1KA1           MSLLMFTQLLLCGFLYVRVDGSRLRQEDFPPRIVEHPSDVIVSKGEPTTL
                                     ::::::::::::::::::::::::::::::
XP_016 RVTRRMWTWAPGLLMMTVVFWGHQGNGQGQGSRLRQEDFPPRIVEHPSDVIVSKGEPTTL
         10        20        30        40        50        60      

               60        70        80        90       100       110
pF1KA1 NCKAEGRPTPTIEWYKDGERVETDKDDPRSHRMLLPSGSLFFLRIVHGRRSKPDEGSYVC
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NCKAEGRPTPTIEWYKDGERVETDKDDPRSHRMLLPSGSLFFLRIVHGRRSKPDEGSYVC
         70        80        90       100       110       120      

              120       130       140       150       160       170
pF1KA1 VARNYLGEAVSRNASLEVALLRDDFRQNPTDVVVAAGEPAILECQPPRGHPEPTIYWKKD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VARNYLGEAVSRNASLEVALLRDDFRQNPTDVVVAAGEPAILECQPPRGHPEPTIYWKKD
        130       140       150       160       170       180      

              180       190       200       210       220       230
pF1KA1 KVRIDDKEERISIRGGKLMISNTRKSDAGMYTCVGTNMVGERDSDPAELTVFERPTFLRR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KVRIDDKEERISIRGGKLMISNTRKSDAGMYTCVGTNMVGERDSDPAELTVFERPTFLRR
        190       200       210       220       230       240      

              240       250       260       270       280       290
pF1KA1 PINQVVLEEEAVEFRCQVQGDPQPTVRWKKDDADLPRGRYDIKDDYTLRIKKTMSTDEGT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PINQVVLEEEAVEFRCQVQGDPQPTVRWKKDDADLPRGRYDIKDDYTLRIKKTMSTDEGT
        250       260       270       280       290       300      

              300       310           320       330       340      
pF1KA1 YMCIAENRVGKMEASATLTVRA----PPQFVVRPRDQIVAQGRTVTFPCETKGNPQPAVF
       ::::::::::::::::::::::    ::::::::::::::::::::::::::::::::::
XP_016 YMCIAENRVGKMEASATLTVRARPVAPPQFVVRPRDQIVAQGRTVTFPCETKGNPQPAVF
        310       320       330       340       350       360      

        350       360       370       380       390       400      
pF1KA1 WQKEGSQNLLFPNQPQQPNSRCSVSPTGDLTITNIQRSDAGYYICQALTVAGSILAKAQL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 WQKEGSQNLLFPNQPQQPNSRCSVSPTGDLTITNIQRSDAGYYICQALTVAGSILAKAQL
        370       380       390       400       410       420      

        410       420       430       440       450       460      
pF1KA1 EVTDVLTDRPPPIILQGPANQTLAVDGTALLKCKATGDPLPVISWLKEGFTFPGRDPRAT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EVTDVLTDRPPPIILQGPANQTLAVDGTALLKCKATGDPLPVISWLKEGFTFPGRDPRAT
        430       440       450       460       470       480      

        470       480       490       500       510       520      
pF1KA1 IQEQGTLQIKNLRISDTGTYTCVATSSSGETSWSAVLDVTESGATISKNYDLSDLPGPPS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IQEQGTLQIKNLRISDTGTYTCVATSSSGETSWSAVLDVTESGATISKNYDLSDLPGPPS
        490       500       510       520       530       540      

        530       540       550       560       570       580      
pF1KA1 KPQVTDVTKNSVTLSWQPGTPGTLPASAYIIEAFSQSVSNSWQTVANHVKTTLYTVRGLR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KPQVTDVTKNSVTLSWQPGTPGTLPASAYIIEAFSQSVSNSWQTVANHVKTTLYTVRGLR
        550       560       570       580       590       600      

        590       600       610       620       630       640      
pF1KA1 PNTIYLFMVRAINPQGLSDPSPMSDPVRTQDISPPAQGVDHRQVQKELGDVLVRLHNPVV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PNTIYLFMVRAINPQGLSDPSPMSDPVRTQDISPPAQGVDHRQVQKELGDVLVRLHNPVV
        610       620       630       640       650       660      

        650       660       670       680       690       700      
pF1KA1 LTPTTVQVTWTVDRQPQFIQGYRVMYRQTSGLQATSSWQNLDAKVPTERSAVLVNLKKGV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LTPTTVQVTWTVDRQPQFIQGYRVMYRQTSGLQATSSWQNLDAKVPTERSAVLVNLKKGV
        670       680       690       700       710       720      

        710       720       730       740       750       760      
pF1KA1 TYEIKVRPYFNEFQGMDSESKTVRTTEEAPSAPPQSVTVLTVGSYNSTSISVSWDPPPPD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TYEIKVRPYFNEFQGMDSESKTVRTTEEAPSAPPQSVTVLTVGSYNSTSISVSWDPPPPD
        730       740       750       760       770       780      

        770       780       790       800       810       820      
pF1KA1 HQNGIIQEYKIWCLGNETRFHINKTVDAAIRSVIIGGLFPGIQYRVEVAASTSAGVGVKS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 HQNGIIQEYKIWCLGNETRFHINKTVDAAIRSVIIGGLFPGIQYRVEVAASTSAGVGVKS
        790       800       810       820       830       840      

        830       840       850       860       870       880      
pF1KA1 EPQPIIIGRRNEVVITENNNSITEQITDVVKQPAFIAGIGGACWVILMGFSIWLYWRRKK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EPQPIIIGRRNEVVITENNNSITEQITDVVKQPAFIAGIGGACWVILMGFSIWLYWRRKK
        850       860       870       880       890       900      

        890       900       910       920       930       940      
pF1KA1 RKGLSNYAVTFQRGDGGLMSNGSRPGLLNAGDPSYPWLADSWPATSLPVNNSNSGPNEIG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RKGLSNYAVTFQRGDGGLMSNGSRPGLLNAGDPSYPWLADSWPATSLPVNNSNSGPNEIG
        910       920       930       940       950       960      

        950       960       970       980       990      1000      
pF1KA1 NFGRGDVLPPVPGQGDKTATMLSDGAIYSSIDFTTKTSYNSSSQITQATPYATTQILHSN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NFGRGDVLPPVPGQGDKTATMLSDGAIYSSIDFTTKTSYNSSSQITQATPYATTQILHSN
        970       980       990      1000      1010      1020      

       1010      1020      1030      1040      1050      1060      
pF1KA1 SIHELAVDLPDPQWKSSIQQKTDLMGFGYSLPDQNKGNNGGKGGKKKKNKNSSKPQKNNG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SIHELAVDLPDPQWKSSIQQKTDLMGFGYSLPDQNKGNNGGKGGKKKKNKNSSKPQKNNG
       1030      1040      1050      1060      1070      1080      

       1070      1080      1090      1100      1110      1120      
pF1KA1 STWANVPLPPPPVQPLPGTELEHYAVEQQENGYDSDSWCPPLPVQTYLHQGLEDELEEDD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 STWANVPLPPPPVQPLPGTELEHYAVEQQENGYDSDSWCPPLPVQTYLHQGLEDELEEDD
       1090      1100      1110      1120      1130      1140      

       1130      1140      1150      1160      1170      1180      
pF1KA1 DRVPTPPVRGVASSPAISFGQQSTATLTPSPREEMQPMLQAHLDELTRAYQFDIAKQTWH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DRVPTPPVRGVASSPAISFGQQSTATLTPSPREEMQPMLQAHLDELTRAYQFDIAKQTWH
       1150      1160      1170      1180      1190      1200      

       1190      1200      1210      1220      1230      1240      
pF1KA1 IQSNNQPPQPPVPPLGYVSGALISDLETDVADDDADDEEEALEIPRPLRALDQTPGSSMD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IQSNNQPPQPPVPPLGYVSGALISDLETDVADDDADDEEEALEIPRPLRALDQTPGSSMD
       1210      1220      1230      1240      1250      1260      

       1250      1260      1270      1280      1290      1300      
pF1KA1 NLDSSVTGKAFTSSQRPRPTSPFSTDSNTSAALSQSQRPRPTKKHKGGRMDQQPALPHRR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NLDSSVTGKAFTSSQRPRPTSPFSTDSNTSAALSQSQRPRPTKKHKGGRMDQQPALPHRR
       1270      1280      1290      1300      1310      1320      

       1310      1320      1330      1340      1350      1360      
pF1KA1 EGMTDEEALVPYSKPSFPSPGGHSSSGTASSKGSTGPRKTEVLRAGHQRNASDLLDIGYM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EGMTDEEALVPYSKPSFPSPGGHSSSGTASSKGSTGPRKTEVLRAGHQRNASDLLDIGYM
       1330      1340      1350      1360      1370      1380      

       1370        
pF1KA1 GSNSQGQFTGEL
       ::::::::::::
XP_016 GSNSQGQFTGEL
       1390        

>>XP_011532287 (OMIM: 602431,610878) PREDICTED: roundabo  (1405 aa)
 initn: 7201 init1: 7201 opt: 9161  Z-score: 4621.3  bits: 867.5 E(85289):    0
Smith-Waterman score: 9161; 99.7% identity (99.7% similar) in 1362 aa overlap (21-1378:44-1405)

                         10        20        30        40        50
pF1KA1           MSLLMFTQLLLCGFLYVRVDGSRLRQEDFPPRIVEHPSDVIVSKGEPTTL
                                     ::::::::::::::::::::::::::::::
XP_011 ELLFVLMLFLSGPTLSKLTRTPWKGKPWKGGSRLRQEDFPPRIVEHPSDVIVSKGEPTTL
            20        30        40        50        60        70   

               60        70        80        90       100       110
pF1KA1 NCKAEGRPTPTIEWYKDGERVETDKDDPRSHRMLLPSGSLFFLRIVHGRRSKPDEGSYVC
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NCKAEGRPTPTIEWYKDGERVETDKDDPRSHRMLLPSGSLFFLRIVHGRRSKPDEGSYVC
            80        90       100       110       120       130   

              120       130       140       150       160       170
pF1KA1 VARNYLGEAVSRNASLEVALLRDDFRQNPTDVVVAAGEPAILECQPPRGHPEPTIYWKKD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VARNYLGEAVSRNASLEVALLRDDFRQNPTDVVVAAGEPAILECQPPRGHPEPTIYWKKD
           140       150       160       170       180       190   

              180       190       200       210       220       230
pF1KA1 KVRIDDKEERISIRGGKLMISNTRKSDAGMYTCVGTNMVGERDSDPAELTVFERPTFLRR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KVRIDDKEERISIRGGKLMISNTRKSDAGMYTCVGTNMVGERDSDPAELTVFERPTFLRR
           200       210       220       230       240       250   

              240       250       260       270       280       290
pF1KA1 PINQVVLEEEAVEFRCQVQGDPQPTVRWKKDDADLPRGRYDIKDDYTLRIKKTMSTDEGT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PINQVVLEEEAVEFRCQVQGDPQPTVRWKKDDADLPRGRYDIKDDYTLRIKKTMSTDEGT
           260       270       280       290       300       310   

              300       310           320       330       340      
pF1KA1 YMCIAENRVGKMEASATLTVRA----PPQFVVRPRDQIVAQGRTVTFPCETKGNPQPAVF
       ::::::::::::::::::::::    ::::::::::::::::::::::::::::::::::
XP_011 YMCIAENRVGKMEASATLTVRARPVAPPQFVVRPRDQIVAQGRTVTFPCETKGNPQPAVF
           320       330       340       350       360       370   

        350       360       370       380       390       400      
pF1KA1 WQKEGSQNLLFPNQPQQPNSRCSVSPTGDLTITNIQRSDAGYYICQALTVAGSILAKAQL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 WQKEGSQNLLFPNQPQQPNSRCSVSPTGDLTITNIQRSDAGYYICQALTVAGSILAKAQL
           380       390       400       410       420       430   

        410       420       430       440       450       460      
pF1KA1 EVTDVLTDRPPPIILQGPANQTLAVDGTALLKCKATGDPLPVISWLKEGFTFPGRDPRAT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EVTDVLTDRPPPIILQGPANQTLAVDGTALLKCKATGDPLPVISWLKEGFTFPGRDPRAT
           440       450       460       470       480       490   

        470       480       490       500       510       520      
pF1KA1 IQEQGTLQIKNLRISDTGTYTCVATSSSGETSWSAVLDVTESGATISKNYDLSDLPGPPS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 IQEQGTLQIKNLRISDTGTYTCVATSSSGETSWSAVLDVTESGATISKNYDLSDLPGPPS
           500       510       520       530       540       550   

        530       540       550       560       570       580      
pF1KA1 KPQVTDVTKNSVTLSWQPGTPGTLPASAYIIEAFSQSVSNSWQTVANHVKTTLYTVRGLR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KPQVTDVTKNSVTLSWQPGTPGTLPASAYIIEAFSQSVSNSWQTVANHVKTTLYTVRGLR
           560       570       580       590       600       610   

        590       600       610       620       630       640      
pF1KA1 PNTIYLFMVRAINPQGLSDPSPMSDPVRTQDISPPAQGVDHRQVQKELGDVLVRLHNPVV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PNTIYLFMVRAINPQGLSDPSPMSDPVRTQDISPPAQGVDHRQVQKELGDVLVRLHNPVV
           620       630       640       650       660       670   

        650       660       670       680       690       700      
pF1KA1 LTPTTVQVTWTVDRQPQFIQGYRVMYRQTSGLQATSSWQNLDAKVPTERSAVLVNLKKGV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LTPTTVQVTWTVDRQPQFIQGYRVMYRQTSGLQATSSWQNLDAKVPTERSAVLVNLKKGV
           680       690       700       710       720       730   

        710       720       730       740       750       760      
pF1KA1 TYEIKVRPYFNEFQGMDSESKTVRTTEEAPSAPPQSVTVLTVGSYNSTSISVSWDPPPPD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TYEIKVRPYFNEFQGMDSESKTVRTTEEAPSAPPQSVTVLTVGSYNSTSISVSWDPPPPD
           740       750       760       770       780       790   

        770       780       790       800       810       820      
pF1KA1 HQNGIIQEYKIWCLGNETRFHINKTVDAAIRSVIIGGLFPGIQYRVEVAASTSAGVGVKS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 HQNGIIQEYKIWCLGNETRFHINKTVDAAIRSVIIGGLFPGIQYRVEVAASTSAGVGVKS
           800       810       820       830       840       850   

        830       840       850       860       870       880      
pF1KA1 EPQPIIIGRRNEVVITENNNSITEQITDVVKQPAFIAGIGGACWVILMGFSIWLYWRRKK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EPQPIIIGRRNEVVITENNNSITEQITDVVKQPAFIAGIGGACWVILMGFSIWLYWRRKK
           860       870       880       890       900       910   

        890       900       910       920       930       940      
pF1KA1 RKGLSNYAVTFQRGDGGLMSNGSRPGLLNAGDPSYPWLADSWPATSLPVNNSNSGPNEIG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RKGLSNYAVTFQRGDGGLMSNGSRPGLLNAGDPSYPWLADSWPATSLPVNNSNSGPNEIG
           920       930       940       950       960       970   

        950       960       970       980       990      1000      
pF1KA1 NFGRGDVLPPVPGQGDKTATMLSDGAIYSSIDFTTKTSYNSSSQITQATPYATTQILHSN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NFGRGDVLPPVPGQGDKTATMLSDGAIYSSIDFTTKTSYNSSSQITQATPYATTQILHSN
           980       990      1000      1010      1020      1030   

       1010      1020      1030      1040      1050      1060      
pF1KA1 SIHELAVDLPDPQWKSSIQQKTDLMGFGYSLPDQNKGNNGGKGGKKKKNKNSSKPQKNNG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SIHELAVDLPDPQWKSSIQQKTDLMGFGYSLPDQNKGNNGGKGGKKKKNKNSSKPQKNNG
          1040      1050      1060      1070      1080      1090   

       1070      1080      1090      1100      1110      1120      
pF1KA1 STWANVPLPPPPVQPLPGTELEHYAVEQQENGYDSDSWCPPLPVQTYLHQGLEDELEEDD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 STWANVPLPPPPVQPLPGTELEHYAVEQQENGYDSDSWCPPLPVQTYLHQGLEDELEEDD
          1100      1110      1120      1130      1140      1150   

       1130      1140      1150      1160      1170      1180      
pF1KA1 DRVPTPPVRGVASSPAISFGQQSTATLTPSPREEMQPMLQAHLDELTRAYQFDIAKQTWH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DRVPTPPVRGVASSPAISFGQQSTATLTPSPREEMQPMLQAHLDELTRAYQFDIAKQTWH
          1160      1170      1180      1190      1200      1210   

       1190      1200      1210      1220      1230      1240      
pF1KA1 IQSNNQPPQPPVPPLGYVSGALISDLETDVADDDADDEEEALEIPRPLRALDQTPGSSMD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 IQSNNQPPQPPVPPLGYVSGALISDLETDVADDDADDEEEALEIPRPLRALDQTPGSSMD
          1220      1230      1240      1250      1260      1270   

       1250      1260      1270      1280      1290      1300      
pF1KA1 NLDSSVTGKAFTSSQRPRPTSPFSTDSNTSAALSQSQRPRPTKKHKGGRMDQQPALPHRR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NLDSSVTGKAFTSSQRPRPTSPFSTDSNTSAALSQSQRPRPTKKHKGGRMDQQPALPHRR
          1280      1290      1300      1310      1320      1330   

       1310      1320      1330      1340      1350      1360      
pF1KA1 EGMTDEEALVPYSKPSFPSPGGHSSSGTASSKGSTGPRKTEVLRAGHQRNASDLLDIGYM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EGMTDEEALVPYSKPSFPSPGGHSSSGTASSKGSTGPRKTEVLRAGHQRNASDLLDIGYM
          1340      1350      1360      1370      1380      1390   

       1370        
pF1KA1 GSNSQGQFTGEL
       ::::::::::::
XP_011 GSNSQGQFTGEL
          1400     

>>XP_016862494 (OMIM: 602431,610878) PREDICTED: roundabo  (1396 aa)
 initn: 7182 init1: 7182 opt: 9142  Z-score: 4611.7  bits: 865.8 E(85289):    0
Smith-Waterman score: 9142; 99.7% identity (99.7% similar) in 1359 aa overlap (21-1375:37-1395)

                         10        20        30        40        50
pF1KA1           MSLLMFTQLLLCGFLYVRVDGSRLRQEDFPPRIVEHPSDVIVSKGEPTTL
                                     ::::::::::::::::::::::::::::::
XP_016 RVTRRMWTWAPGLLMMTVVFWGHQGNGQGQGSRLRQEDFPPRIVEHPSDVIVSKGEPTTL
         10        20        30        40        50        60      

               60        70        80        90       100       110
pF1KA1 NCKAEGRPTPTIEWYKDGERVETDKDDPRSHRMLLPSGSLFFLRIVHGRRSKPDEGSYVC
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NCKAEGRPTPTIEWYKDGERVETDKDDPRSHRMLLPSGSLFFLRIVHGRRSKPDEGSYVC
         70        80        90       100       110       120      

              120       130       140       150       160       170
pF1KA1 VARNYLGEAVSRNASLEVALLRDDFRQNPTDVVVAAGEPAILECQPPRGHPEPTIYWKKD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VARNYLGEAVSRNASLEVALLRDDFRQNPTDVVVAAGEPAILECQPPRGHPEPTIYWKKD
        130       140       150       160       170       180      

              180       190       200       210       220       230
pF1KA1 KVRIDDKEERISIRGGKLMISNTRKSDAGMYTCVGTNMVGERDSDPAELTVFERPTFLRR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KVRIDDKEERISIRGGKLMISNTRKSDAGMYTCVGTNMVGERDSDPAELTVFERPTFLRR
        190       200       210       220       230       240      

              240       250       260       270       280       290
pF1KA1 PINQVVLEEEAVEFRCQVQGDPQPTVRWKKDDADLPRGRYDIKDDYTLRIKKTMSTDEGT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PINQVVLEEEAVEFRCQVQGDPQPTVRWKKDDADLPRGRYDIKDDYTLRIKKTMSTDEGT
        250       260       270       280       290       300      

              300       310           320       330       340      
pF1KA1 YMCIAENRVGKMEASATLTVRA----PPQFVVRPRDQIVAQGRTVTFPCETKGNPQPAVF
       ::::::::::::::::::::::    ::::::::::::::::::::::::::::::::::
XP_016 YMCIAENRVGKMEASATLTVRARPVAPPQFVVRPRDQIVAQGRTVTFPCETKGNPQPAVF
        310       320       330       340       350       360      

        350       360       370       380       390       400      
pF1KA1 WQKEGSQNLLFPNQPQQPNSRCSVSPTGDLTITNIQRSDAGYYICQALTVAGSILAKAQL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 WQKEGSQNLLFPNQPQQPNSRCSVSPTGDLTITNIQRSDAGYYICQALTVAGSILAKAQL
        370       380       390       400       410       420      

        410       420       430       440       450       460      
pF1KA1 EVTDVLTDRPPPIILQGPANQTLAVDGTALLKCKATGDPLPVISWLKEGFTFPGRDPRAT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EVTDVLTDRPPPIILQGPANQTLAVDGTALLKCKATGDPLPVISWLKEGFTFPGRDPRAT
        430       440       450       460       470       480      

        470       480       490       500       510       520      
pF1KA1 IQEQGTLQIKNLRISDTGTYTCVATSSSGETSWSAVLDVTESGATISKNYDLSDLPGPPS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IQEQGTLQIKNLRISDTGTYTCVATSSSGETSWSAVLDVTESGATISKNYDLSDLPGPPS
        490       500       510       520       530       540      

        530       540       550       560       570       580      
pF1KA1 KPQVTDVTKNSVTLSWQPGTPGTLPASAYIIEAFSQSVSNSWQTVANHVKTTLYTVRGLR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KPQVTDVTKNSVTLSWQPGTPGTLPASAYIIEAFSQSVSNSWQTVANHVKTTLYTVRGLR
        550       560       570       580       590       600      

        590       600       610       620       630       640      
pF1KA1 PNTIYLFMVRAINPQGLSDPSPMSDPVRTQDISPPAQGVDHRQVQKELGDVLVRLHNPVV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PNTIYLFMVRAINPQGLSDPSPMSDPVRTQDISPPAQGVDHRQVQKELGDVLVRLHNPVV
        610       620       630       640       650       660      

        650       660       670       680       690       700      
pF1KA1 LTPTTVQVTWTVDRQPQFIQGYRVMYRQTSGLQATSSWQNLDAKVPTERSAVLVNLKKGV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LTPTTVQVTWTVDRQPQFIQGYRVMYRQTSGLQATSSWQNLDAKVPTERSAVLVNLKKGV
        670       680       690       700       710       720      

        710       720       730       740       750       760      
pF1KA1 TYEIKVRPYFNEFQGMDSESKTVRTTEEAPSAPPQSVTVLTVGSYNSTSISVSWDPPPPD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TYEIKVRPYFNEFQGMDSESKTVRTTEEAPSAPPQSVTVLTVGSYNSTSISVSWDPPPPD
        730       740       750       760       770       780      

        770       780       790       800       810       820      
pF1KA1 HQNGIIQEYKIWCLGNETRFHINKTVDAAIRSVIIGGLFPGIQYRVEVAASTSAGVGVKS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 HQNGIIQEYKIWCLGNETRFHINKTVDAAIRSVIIGGLFPGIQYRVEVAASTSAGVGVKS
        790       800       810       820       830       840      

        830       840       850       860       870       880      
pF1KA1 EPQPIIIGRRNEVVITENNNSITEQITDVVKQPAFIAGIGGACWVILMGFSIWLYWRRKK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EPQPIIIGRRNEVVITENNNSITEQITDVVKQPAFIAGIGGACWVILMGFSIWLYWRRKK
        850       860       870       880       890       900      

        890       900       910       920       930       940      
pF1KA1 RKGLSNYAVTFQRGDGGLMSNGSRPGLLNAGDPSYPWLADSWPATSLPVNNSNSGPNEIG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RKGLSNYAVTFQRGDGGLMSNGSRPGLLNAGDPSYPWLADSWPATSLPVNNSNSGPNEIG
        910       920       930       940       950       960      

        950       960       970       980       990      1000      
pF1KA1 NFGRGDVLPPVPGQGDKTATMLSDGAIYSSIDFTTKTSYNSSSQITQATPYATTQILHSN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NFGRGDVLPPVPGQGDKTATMLSDGAIYSSIDFTTKTSYNSSSQITQATPYATTQILHSN
        970       980       990      1000      1010      1020      

       1010      1020      1030      1040      1050      1060      
pF1KA1 SIHELAVDLPDPQWKSSIQQKTDLMGFGYSLPDQNKGNNGGKGGKKKKNKNSSKPQKNNG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SIHELAVDLPDPQWKSSIQQKTDLMGFGYSLPDQNKGNNGGKGGKKKKNKNSSKPQKNNG
       1030      1040      1050      1060      1070      1080      

       1070      1080      1090      1100      1110      1120      
pF1KA1 STWANVPLPPPPVQPLPGTELEHYAVEQQENGYDSDSWCPPLPVQTYLHQGLEDELEEDD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 STWANVPLPPPPVQPLPGTELEHYAVEQQENGYDSDSWCPPLPVQTYLHQGLEDELEEDD
       1090      1100      1110      1120      1130      1140      

       1130      1140      1150      1160      1170      1180      
pF1KA1 DRVPTPPVRGVASSPAISFGQQSTATLTPSPREEMQPMLQAHLDELTRAYQFDIAKQTWH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DRVPTPPVRGVASSPAISFGQQSTATLTPSPREEMQPMLQAHLDELTRAYQFDIAKQTWH
       1150      1160      1170      1180      1190      1200      

       1190      1200      1210      1220      1230      1240      
pF1KA1 IQSNNQPPQPPVPPLGYVSGALISDLETDVADDDADDEEEALEIPRPLRALDQTPGSSMD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IQSNNQPPQPPVPPLGYVSGALISDLETDVADDDADDEEEALEIPRPLRALDQTPGSSMD
       1210      1220      1230      1240      1250      1260      

       1250      1260      1270      1280      1290      1300      
pF1KA1 NLDSSVTGKAFTSSQRPRPTSPFSTDSNTSAALSQSQRPRPTKKHKGGRMDQQPALPHRR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NLDSSVTGKAFTSSQRPRPTSPFSTDSNTSAALSQSQRPRPTKKHKGGRMDQQPALPHRR
       1270      1280      1290      1300      1310      1320      

       1310      1320      1330      1340      1350      1360      
pF1KA1 EGMTDEEALVPYSKPSFPSPGGHSSSGTASSKGSTGPRKTEVLRAGHQRNASDLLDIGYM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EGMTDEEALVPYSKPSFPSPGGHSSSGTASSKGSTGPRKTEVLRAGHQRNASDLLDIGYM
       1330      1340      1350      1360      1370      1380      

       1370        
pF1KA1 GSNSQGQFTGEL
       :::::::::   
XP_016 GSNSQGQFTE  
       1390        

>>XP_016862490 (OMIM: 602431,610878) PREDICTED: roundabo  (1403 aa)
 initn: 7182 init1: 7182 opt: 9142  Z-score: 4611.7  bits: 865.8 E(85289):    0
Smith-Waterman score: 9142; 99.7% identity (99.7% similar) in 1359 aa overlap (21-1375:44-1402)

                         10        20        30        40        50
pF1KA1           MSLLMFTQLLLCGFLYVRVDGSRLRQEDFPPRIVEHPSDVIVSKGEPTTL
                                     ::::::::::::::::::::::::::::::
XP_016 ELLFVLMLFLSGPTLSKLTRTPWKGKPWKGGSRLRQEDFPPRIVEHPSDVIVSKGEPTTL
            20        30        40        50        60        70   

               60        70        80        90       100       110
pF1KA1 NCKAEGRPTPTIEWYKDGERVETDKDDPRSHRMLLPSGSLFFLRIVHGRRSKPDEGSYVC
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NCKAEGRPTPTIEWYKDGERVETDKDDPRSHRMLLPSGSLFFLRIVHGRRSKPDEGSYVC
            80        90       100       110       120       130   

              120       130       140       150       160       170
pF1KA1 VARNYLGEAVSRNASLEVALLRDDFRQNPTDVVVAAGEPAILECQPPRGHPEPTIYWKKD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VARNYLGEAVSRNASLEVALLRDDFRQNPTDVVVAAGEPAILECQPPRGHPEPTIYWKKD
           140       150       160       170       180       190   

              180       190       200       210       220       230
pF1KA1 KVRIDDKEERISIRGGKLMISNTRKSDAGMYTCVGTNMVGERDSDPAELTVFERPTFLRR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KVRIDDKEERISIRGGKLMISNTRKSDAGMYTCVGTNMVGERDSDPAELTVFERPTFLRR
           200       210       220       230       240       250   

              240       250       260       270       280       290
pF1KA1 PINQVVLEEEAVEFRCQVQGDPQPTVRWKKDDADLPRGRYDIKDDYTLRIKKTMSTDEGT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PINQVVLEEEAVEFRCQVQGDPQPTVRWKKDDADLPRGRYDIKDDYTLRIKKTMSTDEGT
           260       270       280       290       300       310   

              300       310           320       330       340      
pF1KA1 YMCIAENRVGKMEASATLTVRA----PPQFVVRPRDQIVAQGRTVTFPCETKGNPQPAVF
       ::::::::::::::::::::::    ::::::::::::::::::::::::::::::::::
XP_016 YMCIAENRVGKMEASATLTVRARPVAPPQFVVRPRDQIVAQGRTVTFPCETKGNPQPAVF
           320       330       340       350       360       370   

        350       360       370       380       390       400      
pF1KA1 WQKEGSQNLLFPNQPQQPNSRCSVSPTGDLTITNIQRSDAGYYICQALTVAGSILAKAQL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 WQKEGSQNLLFPNQPQQPNSRCSVSPTGDLTITNIQRSDAGYYICQALTVAGSILAKAQL
           380       390       400       410       420       430   

        410       420       430       440       450       460      
pF1KA1 EVTDVLTDRPPPIILQGPANQTLAVDGTALLKCKATGDPLPVISWLKEGFTFPGRDPRAT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EVTDVLTDRPPPIILQGPANQTLAVDGTALLKCKATGDPLPVISWLKEGFTFPGRDPRAT
           440       450       460       470       480       490   

        470       480       490       500       510       520      
pF1KA1 IQEQGTLQIKNLRISDTGTYTCVATSSSGETSWSAVLDVTESGATISKNYDLSDLPGPPS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IQEQGTLQIKNLRISDTGTYTCVATSSSGETSWSAVLDVTESGATISKNYDLSDLPGPPS
           500       510       520       530       540       550   

        530       540       550       560       570       580      
pF1KA1 KPQVTDVTKNSVTLSWQPGTPGTLPASAYIIEAFSQSVSNSWQTVANHVKTTLYTVRGLR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KPQVTDVTKNSVTLSWQPGTPGTLPASAYIIEAFSQSVSNSWQTVANHVKTTLYTVRGLR
           560       570       580       590       600       610   

        590       600       610       620       630       640      
pF1KA1 PNTIYLFMVRAINPQGLSDPSPMSDPVRTQDISPPAQGVDHRQVQKELGDVLVRLHNPVV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PNTIYLFMVRAINPQGLSDPSPMSDPVRTQDISPPAQGVDHRQVQKELGDVLVRLHNPVV
           620       630       640       650       660       670   

        650       660       670       680       690       700      
pF1KA1 LTPTTVQVTWTVDRQPQFIQGYRVMYRQTSGLQATSSWQNLDAKVPTERSAVLVNLKKGV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LTPTTVQVTWTVDRQPQFIQGYRVMYRQTSGLQATSSWQNLDAKVPTERSAVLVNLKKGV
           680       690       700       710       720       730   

        710       720       730       740       750       760      
pF1KA1 TYEIKVRPYFNEFQGMDSESKTVRTTEEAPSAPPQSVTVLTVGSYNSTSISVSWDPPPPD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TYEIKVRPYFNEFQGMDSESKTVRTTEEAPSAPPQSVTVLTVGSYNSTSISVSWDPPPPD
           740       750       760       770       780       790   

        770       780       790       800       810       820      
pF1KA1 HQNGIIQEYKIWCLGNETRFHINKTVDAAIRSVIIGGLFPGIQYRVEVAASTSAGVGVKS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 HQNGIIQEYKIWCLGNETRFHINKTVDAAIRSVIIGGLFPGIQYRVEVAASTSAGVGVKS
           800       810       820       830       840       850   

        830       840       850       860       870       880      
pF1KA1 EPQPIIIGRRNEVVITENNNSITEQITDVVKQPAFIAGIGGACWVILMGFSIWLYWRRKK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EPQPIIIGRRNEVVITENNNSITEQITDVVKQPAFIAGIGGACWVILMGFSIWLYWRRKK
           860       870       880       890       900       910   

        890       900       910       920       930       940      
pF1KA1 RKGLSNYAVTFQRGDGGLMSNGSRPGLLNAGDPSYPWLADSWPATSLPVNNSNSGPNEIG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RKGLSNYAVTFQRGDGGLMSNGSRPGLLNAGDPSYPWLADSWPATSLPVNNSNSGPNEIG
           920       930       940       950       960       970   

        950       960       970       980       990      1000      
pF1KA1 NFGRGDVLPPVPGQGDKTATMLSDGAIYSSIDFTTKTSYNSSSQITQATPYATTQILHSN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NFGRGDVLPPVPGQGDKTATMLSDGAIYSSIDFTTKTSYNSSSQITQATPYATTQILHSN
           980       990      1000      1010      1020      1030   

       1010      1020      1030      1040      1050      1060      
pF1KA1 SIHELAVDLPDPQWKSSIQQKTDLMGFGYSLPDQNKGNNGGKGGKKKKNKNSSKPQKNNG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SIHELAVDLPDPQWKSSIQQKTDLMGFGYSLPDQNKGNNGGKGGKKKKNKNSSKPQKNNG
          1040      1050      1060      1070      1080      1090   

       1070      1080      1090      1100      1110      1120      
pF1KA1 STWANVPLPPPPVQPLPGTELEHYAVEQQENGYDSDSWCPPLPVQTYLHQGLEDELEEDD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 STWANVPLPPPPVQPLPGTELEHYAVEQQENGYDSDSWCPPLPVQTYLHQGLEDELEEDD
          1100      1110      1120      1130      1140      1150   

       1130      1140      1150      1160      1170      1180      
pF1KA1 DRVPTPPVRGVASSPAISFGQQSTATLTPSPREEMQPMLQAHLDELTRAYQFDIAKQTWH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DRVPTPPVRGVASSPAISFGQQSTATLTPSPREEMQPMLQAHLDELTRAYQFDIAKQTWH
          1160      1170      1180      1190      1200      1210   

       1190      1200      1210      1220      1230      1240      
pF1KA1 IQSNNQPPQPPVPPLGYVSGALISDLETDVADDDADDEEEALEIPRPLRALDQTPGSSMD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IQSNNQPPQPPVPPLGYVSGALISDLETDVADDDADDEEEALEIPRPLRALDQTPGSSMD
          1220      1230      1240      1250      1260      1270   

       1250      1260      1270      1280      1290      1300      
pF1KA1 NLDSSVTGKAFTSSQRPRPTSPFSTDSNTSAALSQSQRPRPTKKHKGGRMDQQPALPHRR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NLDSSVTGKAFTSSQRPRPTSPFSTDSNTSAALSQSQRPRPTKKHKGGRMDQQPALPHRR
          1280      1290      1300      1310      1320      1330   

       1310      1320      1330      1340      1350      1360      
pF1KA1 EGMTDEEALVPYSKPSFPSPGGHSSSGTASSKGSTGPRKTEVLRAGHQRNASDLLDIGYM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EGMTDEEALVPYSKPSFPSPGGHSSSGTASSKGSTGPRKTEVLRAGHQRNASDLLDIGYM
          1340      1350      1360      1370      1380      1390   

       1370        
pF1KA1 GSNSQGQFTGEL
       :::::::::   
XP_016 GSNSQGQFTE  
          1400     

>>XP_016862491 (OMIM: 602431,610878) PREDICTED: roundabo  (1402 aa)
 initn: 5001 init1: 4950 opt: 9123  Z-score: 4602.2  bits: 864.0 E(85289):    0
Smith-Waterman score: 9123; 99.5% identity (99.5% similar) in 1362 aa overlap (21-1378:44-1402)

                         10        20        30        40        50
pF1KA1           MSLLMFTQLLLCGFLYVRVDGSRLRQEDFPPRIVEHPSDVIVSKGEPTTL
                                     ::::::::::::::::::::::::::::::
XP_016 ELLFVLMLFLSGPTLSKLTRTPWKGKPWKGGSRLRQEDFPPRIVEHPSDVIVSKGEPTTL
            20        30        40        50        60        70   

               60        70        80        90       100       110
pF1KA1 NCKAEGRPTPTIEWYKDGERVETDKDDPRSHRMLLPSGSLFFLRIVHGRRSKPDEGSYVC
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NCKAEGRPTPTIEWYKDGERVETDKDDPRSHRMLLPSGSLFFLRIVHGRRSKPDEGSYVC
            80        90       100       110       120       130   

              120       130       140       150       160       170
pF1KA1 VARNYLGEAVSRNASLEVALLRDDFRQNPTDVVVAAGEPAILECQPPRGHPEPTIYWKKD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VARNYLGEAVSRNASLEVALLRDDFRQNPTDVVVAAGEPAILECQPPRGHPEPTIYWKKD
           140       150       160       170       180       190   

              180       190       200       210       220       230
pF1KA1 KVRIDDKEERISIRGGKLMISNTRKSDAGMYTCVGTNMVGERDSDPAELTVFERPTFLRR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KVRIDDKEERISIRGGKLMISNTRKSDAGMYTCVGTNMVGERDSDPAELTVFERPTFLRR
           200       210       220       230       240       250   

              240       250       260       270       280       290
pF1KA1 PINQVVLEEEAVEFRCQVQGDPQPTVRWKKDDADLPRGRYDIKDDYTLRIKKTMSTDEGT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PINQVVLEEEAVEFRCQVQGDPQPTVRWKKDDADLPRGRYDIKDDYTLRIKKTMSTDEGT
           260       270       280       290       300       310   

              300       310           320       330       340      
pF1KA1 YMCIAENRVGKMEASATLTVRA----PPQFVVRPRDQIVAQGRTVTFPCETKGNPQPAVF
       ::::::::::::::::::::::    ::::::::::::::::::::::::::::::::::
XP_016 YMCIAENRVGKMEASATLTVRARPVAPPQFVVRPRDQIVAQGRTVTFPCETKGNPQPAVF
           320       330       340       350       360       370   

        350       360       370       380       390       400      
pF1KA1 WQKEGSQNLLFPNQPQQPNSRCSVSPTGDLTITNIQRSDAGYYICQALTVAGSILAKAQL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 WQKEGSQNLLFPNQPQQPNSRCSVSPTGDLTITNIQRSDAGYYICQALTVAGSILAKAQL
           380       390       400       410       420       430   

        410       420       430       440       450       460      
pF1KA1 EVTDVLTDRPPPIILQGPANQTLAVDGTALLKCKATGDPLPVISWLKEGFTFPGRDPRAT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EVTDVLTDRPPPIILQGPANQTLAVDGTALLKCKATGDPLPVISWLKEGFTFPGRDPRAT
           440       450       460       470       480       490   

        470       480       490       500       510       520      
pF1KA1 IQEQGTLQIKNLRISDTGTYTCVATSSSGETSWSAVLDVTESGATISKNYDLSDLPGPPS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IQEQGTLQIKNLRISDTGTYTCVATSSSGETSWSAVLDVTESGATISKNYDLSDLPGPPS
           500       510       520       530       540       550   

        530       540       550       560       570       580      
pF1KA1 KPQVTDVTKNSVTLSWQPGTPGTLPASAYIIEAFSQSVSNSWQTVANHVKTTLYTVRGLR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KPQVTDVTKNSVTLSWQPGTPGTLPASAYIIEAFSQSVSNSWQTVANHVKTTLYTVRGLR
           560       570       580       590       600       610   

        590       600       610       620       630       640      
pF1KA1 PNTIYLFMVRAINPQGLSDPSPMSDPVRTQDISPPAQGVDHRQVQKELGDVLVRLHNPVV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PNTIYLFMVRAINPQGLSDPSPMSDPVRTQDISPPAQGVDHRQVQKELGDVLVRLHNPVV
           620       630       640       650       660       670   

        650       660       670       680       690       700      
pF1KA1 LTPTTVQVTWTVDRQPQFIQGYRVMYRQTSGLQATSSWQNLDAKVPTERSAVLVNLKKGV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LTPTTVQVTWTVDRQPQFIQGYRVMYRQTSGLQATSSWQNLDAKVPTERSAVLVNLKKGV
           680       690       700       710       720       730   

        710       720       730       740       750       760      
pF1KA1 TYEIKVRPYFNEFQGMDSESKTVRTTEEAPSAPPQSVTVLTVGSYNSTSISVSWDPPPPD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TYEIKVRPYFNEFQGMDSESKTVRTTEEAPSAPPQSVTVLTVGSYNSTSISVSWDPPPPD
           740       750       760       770       780       790   

        770       780       790       800       810       820      
pF1KA1 HQNGIIQEYKIWCLGNETRFHINKTVDAAIRSVIIGGLFPGIQYRVEVAASTSAGVGVKS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 HQNGIIQEYKIWCLGNETRFHINKTVDAAIRSVIIGGLFPGIQYRVEVAASTSAGVGVKS
           800       810       820       830       840       850   

        830       840       850       860       870       880      
pF1KA1 EPQPIIIGRRNEVVITENNNSITEQITDVVKQPAFIAGIGGACWVILMGFSIWLYWRRKK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EPQPIIIGRRNEVVITENNNSITEQITDVVKQPAFIAGIGGACWVILMGFSIWLYWRRKK
           860       870       880       890       900       910   

        890       900       910       920       930       940      
pF1KA1 RKGLSNYAVTFQRGDGGLMSNGSRPGLLNAGDPSYPWLADSWPATSLPVNNSNSGPNEIG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RKGLSNYAVTFQRGDGGLMSNGSRPGLLNAGDPSYPWLADSWPATSLPVNNSNSGPNEIG
           920       930       940       950       960       970   

        950       960       970       980       990      1000      
pF1KA1 NFGRGDVLPPVPGQGDKTATMLSDGAIYSSIDFTTKTSYNSSSQITQATPYATTQILHSN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NFGRGDVLPPVPGQGDKTATMLSDGAIYSSIDFTTKTSYNSSSQITQATPYATTQILHSN
           980       990      1000      1010      1020      1030   

       1010      1020      1030      1040      1050      1060      
pF1KA1 SIHELAVDLPDPQWKSSIQQKTDLMGFGYSLPDQNKGNNGGKGGKKKKNKNSSKPQKNNG
       :::::::::::::::::::::::::::::::::::::   ::::::::::::::::::::
XP_016 SIHELAVDLPDPQWKSSIQQKTDLMGFGYSLPDQNKG---GKGGKKKKNKNSSKPQKNNG
          1040      1050      1060      1070         1080      1090

       1070      1080      1090      1100      1110      1120      
pF1KA1 STWANVPLPPPPVQPLPGTELEHYAVEQQENGYDSDSWCPPLPVQTYLHQGLEDELEEDD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 STWANVPLPPPPVQPLPGTELEHYAVEQQENGYDSDSWCPPLPVQTYLHQGLEDELEEDD
             1100      1110      1120      1130      1140      1150

       1130      1140      1150      1160      1170      1180      
pF1KA1 DRVPTPPVRGVASSPAISFGQQSTATLTPSPREEMQPMLQAHLDELTRAYQFDIAKQTWH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DRVPTPPVRGVASSPAISFGQQSTATLTPSPREEMQPMLQAHLDELTRAYQFDIAKQTWH
             1160      1170      1180      1190      1200      1210

       1190      1200      1210      1220      1230      1240      
pF1KA1 IQSNNQPPQPPVPPLGYVSGALISDLETDVADDDADDEEEALEIPRPLRALDQTPGSSMD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IQSNNQPPQPPVPPLGYVSGALISDLETDVADDDADDEEEALEIPRPLRALDQTPGSSMD
             1220      1230      1240      1250      1260      1270

       1250      1260      1270      1280      1290      1300      
pF1KA1 NLDSSVTGKAFTSSQRPRPTSPFSTDSNTSAALSQSQRPRPTKKHKGGRMDQQPALPHRR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NLDSSVTGKAFTSSQRPRPTSPFSTDSNTSAALSQSQRPRPTKKHKGGRMDQQPALPHRR
             1280      1290      1300      1310      1320      1330

       1310      1320      1330      1340      1350      1360      
pF1KA1 EGMTDEEALVPYSKPSFPSPGGHSSSGTASSKGSTGPRKTEVLRAGHQRNASDLLDIGYM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EGMTDEEALVPYSKPSFPSPGGHSSSGTASSKGSTGPRKTEVLRAGHQRNASDLLDIGYM
             1340      1350      1360      1370      1380      1390

       1370        
pF1KA1 GSNSQGQFTGEL
       ::::::::::::
XP_016 GSNSQGQFTGEL
             1400  




1378 residues in 1 query   sequences
60827320 residues in 85289 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Wed Nov  2 21:25:46 2016 done: Wed Nov  2 21:25:48 2016
 Total Scan time: 12.890 Total Display time:  0.660

Function used was FASTA [36.3.4 Apr, 2011]
Inquiries or Suggestions ?
Send a message to flexiclone AT kazusagt.com