Result of FASTA (omim) for pF1KA1016
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KA1016, 728 aa
  1>>>pF1KA1016 728 - 728 aa - 728 aa
Library: /omim/omim.rfq.tfa
  60827320 residues in 85289 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 7.9990+/-0.00041; mu= 8.0080+/- 0.026
 mean_var=178.1503+/-37.057, 0's: 0 Z-trim(118.0): 183  B-trim: 1374 in 1/54
 Lambda= 0.096091
 statistics sampled from 30325 (30526) to 30325 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.7), E-opt: 0.2 (0.358), width:  16
 Scan time: 12.000

The best scores are:                                      opt bits E(85289)
NP_055931 (OMIM: 610368) leucine-rich repeat and c ( 728) 4862 686.9 7.4e-197
NP_001157685 (OMIM: 610368) leucine-rich repeat an ( 696) 4433 627.4 5.7e-179
NP_001157683 (OMIM: 610368) leucine-rich repeat an ( 763) 3683 523.5 1.2e-147
XP_016875972 (OMIM: 610368) PREDICTED: leucine-ric ( 731) 3672 522.0 3.4e-147
XP_016875973 (OMIM: 610368) PREDICTED: leucine-ric ( 477) 1963 284.9 5.1e-76
NP_036557 (OMIM: 179555) ras suppressor protein 1  ( 277)  355 61.8 4.3e-09
XP_011542154 (OMIM: 605352) PREDICTED: malignant f (1003)  343 60.6 3.6e-08
NP_004216 (OMIM: 605352) malignant fibrous histioc (1052)  343 60.6 3.8e-08
NP_665894 (OMIM: 605247) p53-induced protein with  ( 893)  316 56.8 4.5e-07
XP_011518513 (OMIM: 605247) PREDICTED: p53-induced ( 893)  316 56.8 4.5e-07
XP_011518512 (OMIM: 605247) PREDICTED: p53-induced ( 910)  316 56.8 4.5e-07
NP_665893 (OMIM: 605247) p53-induced protein with  ( 910)  316 56.8 4.5e-07
XP_011518511 (OMIM: 605247) PREDICTED: p53-induced ( 920)  316 56.8 4.6e-07
XP_005253064 (OMIM: 605247) PREDICTED: p53-induced ( 934)  316 56.8 4.6e-07
XP_005253062 (OMIM: 605247) PREDICTED: p53-induced ( 934)  316 56.8 4.6e-07
XP_005253063 (OMIM: 605247) PREDICTED: p53-induced ( 934)  316 56.8 4.6e-07
XP_016857384 (OMIM: 614453) PREDICTED: leucine-ric (1255)  311 56.2 9.4e-07
XP_016857383 (OMIM: 614453) PREDICTED: leucine-ric (1438)  311 56.3   1e-06
XP_016857382 (OMIM: 614453) PREDICTED: leucine-ric (1472)  311 56.3 1.1e-06
XP_016857381 (OMIM: 614453) PREDICTED: leucine-ric (1490)  311 56.3 1.1e-06
NP_001317564 (OMIM: 614453) leucine-rich repeat-co (1495)  311 56.3 1.1e-06
XP_016857379 (OMIM: 614453) PREDICTED: leucine-ric (1528)  311 56.3 1.1e-06
XP_016857378 (OMIM: 614453) PREDICTED: leucine-ric (1537)  311 56.3 1.1e-06
NP_065845 (OMIM: 614453) leucine-rich repeat-conta (1537)  311 56.3 1.1e-06
XP_016857377 (OMIM: 614453) PREDICTED: leucine-ric (1541)  311 56.3 1.1e-06
XP_016857376 (OMIM: 614453) PREDICTED: leucine-ric (1547)  311 56.3 1.1e-06
XP_016857374 (OMIM: 614453) PREDICTED: leucine-ric (1594)  311 56.3 1.1e-06
XP_016857375 (OMIM: 614453) PREDICTED: leucine-ric (1594)  311 56.3 1.1e-06
XP_005252609 (OMIM: 179555) PREDICTED: ras suppres ( 277)  290 52.8 2.2e-06
NP_001255968 (OMIM: 602775,607721) leucine-rich re ( 536)  295 53.7 2.3e-06
XP_016872192 (OMIM: 602775,607721) PREDICTED: leuc ( 582)  295 53.7 2.4e-06
NP_031399 (OMIM: 602775,607721) leucine-rich repea ( 582)  295 53.7 2.4e-06
NP_001311265 (OMIM: 602775,607721) leucine-rich re ( 582)  295 53.7 2.4e-06
NP_001311266 (OMIM: 602775,607721) leucine-rich re ( 582)  295 53.7 2.4e-06
XP_016872193 (OMIM: 602775,607721) PREDICTED: leuc ( 582)  295 53.7 2.4e-06
XP_016872191 (OMIM: 602775,607721) PREDICTED: leuc ( 582)  295 53.7 2.4e-06
XP_006717379 (OMIM: 610933,614436) PREDICTED: E3 u ( 690)  296 53.9 2.5e-06
XP_006714723 (OMIM: 606944) PREDICTED: protein LAP (1246)  299 54.5 2.9e-06
XP_016865126 (OMIM: 606944) PREDICTED: protein LAP (1298)  299 54.6   3e-06
NP_001006600 (OMIM: 606944) erbin isoform 7 [Homo  (1302)  299 54.6 3.1e-06
NP_001240627 (OMIM: 606944) erbin isoform 4 [Homo  (1346)  299 54.6 3.1e-06
NP_001240630 (OMIM: 606944) erbin isoform 9 [Homo  (1367)  299 54.6 3.2e-06
NP_061165 (OMIM: 606944) erbin isoform 2 [Homo sap (1371)  299 54.6 3.2e-06
NP_001240626 (OMIM: 606944) erbin isoform 1 [Homo  (1412)  299 54.6 3.2e-06
XP_016865125 (OMIM: 606944) PREDICTED: protein LAP (1415)  299 54.6 3.3e-06
NP_001240628 (OMIM: 606944) erbin isoform 8 [Homo  (1419)  299 54.6 3.3e-06
XP_005248612 (OMIM: 606944) PREDICTED: protein LAP (1456)  299 54.6 3.3e-06
XP_005248611 (OMIM: 606944) PREDICTED: protein LAP (1460)  299 54.6 3.3e-06
XP_016865124 (OMIM: 606944) PREDICTED: protein LAP (1460)  299 54.6 3.3e-06
XP_016866486 (OMIM: 608195) PREDICTED: leucine-ric ( 331)  285 52.2 4.1e-06


>>NP_055931 (OMIM: 610368) leucine-rich repeat and calpo  (728 aa)
 initn: 4862 init1: 4862 opt: 4862  Z-score: 3655.2  bits: 686.9 E(85289): 7.4e-197
Smith-Waterman score: 4862; 100.0% identity (100.0% similar) in 728 aa overlap (1-728:1-728)

               10        20        30        40        50        60
pF1KA1 MATPGSEPQPFVPALSVATLHPLHHPHHHHHHHQHHGGTGAPGGAGGGGGGSGGFNLPLN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 MATPGSEPQPFVPALSVATLHPLHHPHHHHHHHQHHGGTGAPGGAGGGGGGSGGFNLPLN
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KA1 RGLERALEEAANSGGLNLSARKLKEFPRTAAPGHDLSDTVQADLSKNRLVEVPMELCHFV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 RGLERALEEAANSGGLNLSARKLKEFPRTAAPGHDLSDTVQADLSKNRLVEVPMELCHFV
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KA1 SLEILNLYHNCIRVIPEAIVNLQMLTYLNLSRNQLSALPACLCGLPLKVLIASNNKLGSL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 SLEILNLYHNCIRVIPEAIVNLQMLTYLNLSRNQLSALPACLCGLPLKVLIASNNKLGSL
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KA1 PEEIGQLKQLMELDVSCNEITALPQQIGQLKSLRELNVRRNYLKVLPQELVDLPLVKFDF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 PEEIGQLKQLMELDVSCNEITALPQQIGQLKSLRELNVRRNYLKVLPQELVDLPLVKFDF
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KA1 SCNKVLVIPICFREMKQLQVLLLENNPLQSPPAQICTKGKVHIFKYLSIQACQIKTADSL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 SCNKVLVIPICFREMKQLQVLLLENNPLQSPPAQICTKGKVHIFKYLSIQACQIKTADSL
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KA1 YLHTMERPHLHQHVEDGKKDSDSGVGSDNGDKRLSATEPSDEDTVSLNVPMSNIMEEEQI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 YLHTMERPHLHQHVEDGKKDSDSGVGSDNGDKRLSATEPSDEDTVSLNVPMSNIMEEEQI
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KA1 IKEDSCHRLSPVKGEFHQEFQPEPSLLGDSTNSGEERDQFTDRADGLHSEFMNYKARAED
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 IKEDSCHRLSPVKGEFHQEFQPEPSLLGDSTNSGEERDQFTDRADGLHSEFMNYKARAED
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KA1 CEELLRIEEDVHWQTEGIISSSKDQDMDIAMIEQLREAVDLLQDPNGLSTDITERSVLNL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 CEELLRIEEDVHWQTEGIISSSKDQDMDIAMIEQLREAVDLLQDPNGLSTDITERSVLNL
              430       440       450       460       470       480

              490       500       510       520       530       540
pF1KA1 YPMGSAEALELQDSALNGQIQLETSPVCEVQSDLTLQSNGSQYSPNEIRENSPAVSPTTN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 YPMGSAEALELQDSALNGQIQLETSPVCEVQSDLTLQSNGSQYSPNEIRENSPAVSPTTN
              490       500       510       520       530       540

              550       560       570       580       590       600
pF1KA1 STAPFGLKPRSVFLRPQRNLESIDPQFTIRRKMEQMREEKELVEQLRESIEMRLKVSLHE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 STAPFGLKPRSVFLRPQRNLESIDPQFTIRRKMEQMREEKELVEQLRESIEMRLKVSLHE
              550       560       570       580       590       600

              610       620       630       640       650       660
pF1KA1 DLGAALMDGVVLCHLVNHIRPRSVASIHVPSPAVPKLSMAKCRRNVENFLEACRKLGVPE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 DLGAALMDGVVLCHLVNHIRPRSVASIHVPSPAVPKLSMAKCRRNVENFLEACRKLGVPE
              610       620       630       640       650       660

              670       680       690       700       710       720
pF1KA1 ADLCSPCDILQLDFRHIRKTVDTLLALGEKAPPPTSALRSRDLIGFCLVHILFIVLVYIT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 ADLCSPCDILQLDFRHIRKTVDTLLALGEKAPPPTSALRSRDLIGFCLVHILFIVLVYIT
              670       680       690       700       710       720

               
pF1KA1 YHWNALSA
       ::::::::
NP_055 YHWNALSA
               

>>NP_001157685 (OMIM: 610368) leucine-rich repeat and ca  (696 aa)
 initn: 4836 init1: 4433 opt: 4433  Z-score: 3334.1  bits: 627.4 E(85289): 5.7e-179
Smith-Waterman score: 4433; 99.1% identity (99.3% similar) in 671 aa overlap (1-671:1-671)

               10        20        30        40        50        60
pF1KA1 MATPGSEPQPFVPALSVATLHPLHHPHHHHHHHQHHGGTGAPGGAGGGGGGSGGFNLPLN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MATPGSEPQPFVPALSVATLHPLHHPHHHHHHHQHHGGTGAPGGAGGGGGGSGGFNLPLN
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KA1 RGLERALEEAANSGGLNLSARKLKEFPRTAAPGHDLSDTVQADLSKNRLVEVPMELCHFV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RGLERALEEAANSGGLNLSARKLKEFPRTAAPGHDLSDTVQADLSKNRLVEVPMELCHFV
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KA1 SLEILNLYHNCIRVIPEAIVNLQMLTYLNLSRNQLSALPACLCGLPLKVLIASNNKLGSL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SLEILNLYHNCIRVIPEAIVNLQMLTYLNLSRNQLSALPACLCGLPLKVLIASNNKLGSL
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KA1 PEEIGQLKQLMELDVSCNEITALPQQIGQLKSLRELNVRRNYLKVLPQELVDLPLVKFDF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PEEIGQLKQLMELDVSCNEITALPQQIGQLKSLRELNVRRNYLKVLPQELVDLPLVKFDF
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KA1 SCNKVLVIPICFREMKQLQVLLLENNPLQSPPAQICTKGKVHIFKYLSIQACQIKTADSL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SCNKVLVIPICFREMKQLQVLLLENNPLQSPPAQICTKGKVHIFKYLSIQACQIKTADSL
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KA1 YLHTMERPHLHQHVEDGKKDSDSGVGSDNGDKRLSATEPSDEDTVSLNVPMSNIMEEEQI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 YLHTMERPHLHQHVEDGKKDSDSGVGSDNGDKRLSATEPSDEDTVSLNVPMSNIMEEEQI
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KA1 IKEDSCHRLSPVKGEFHQEFQPEPSLLGDSTNSGEERDQFTDRADGLHSEFMNYKARAED
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IKEDSCHRLSPVKGEFHQEFQPEPSLLGDSTNSGEERDQFTDRADGLHSEFMNYKARAED
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KA1 CEELLRIEEDVHWQTEGIISSSKDQDMDIAMIEQLREAVDLLQDPNGLSTDITERSVLNL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 CEELLRIEEDVHWQTEGIISSSKDQDMDIAMIEQLREAVDLLQDPNGLSTDITERSVLNL
              430       440       450       460       470       480

              490       500       510       520       530       540
pF1KA1 YPMGSAEALELQDSALNGQIQLETSPVCEVQSDLTLQSNGSQYSPNEIRENSPAVSPTTN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 YPMGSAEALELQDSALNGQIQLETSPVCEVQSDLTLQSNGSQYSPNEIRENSPAVSPTTN
              490       500       510       520       530       540

              550       560       570       580       590       600
pF1KA1 STAPFGLKPRSVFLRPQRNLESIDPQFTIRRKMEQMREEKELVEQLRESIEMRLKVSLHE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 STAPFGLKPRSVFLRPQRNLESIDPQFTIRRKMEQMREEKELVEQLRESIEMRLKVSLHE
              550       560       570       580       590       600

              610       620       630       640       650       660
pF1KA1 DLGAALMDGVVLCHLVNHIRPRSVASIHVPSPAVPKLSMAKCRRNVENFLEACRKLGVPE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DLGAALMDGVVLCHLVNHIRPRSVASIHVPSPAVPKLSMAKCRRNVENFLEACRKLGVPE
              610       620       630       640       650       660

              670       680       690       700       710       720
pF1KA1 ADLCSPCDILQLDFRHIRKTVDTLLALGEKAPPPTSALRSRDLIGFCLVHILFIVLVYIT
         :: :  ::.                                                 
NP_001 EKLCLPHHILEEKGLVKVGITIQALLDITVTKALFT                        
              670       680       690                              

>>NP_001157683 (OMIM: 610368) leucine-rich repeat and ca  (763 aa)
 initn: 3683 init1: 3683 opt: 3683  Z-score: 2771.6  bits: 523.5 E(85289): 1.2e-147
Smith-Waterman score: 4767; 95.4% identity (95.4% similar) in 760 aa overlap (1-725:1-760)

               10        20        30        40        50        60
pF1KA1 MATPGSEPQPFVPALSVATLHPLHHPHHHHHHHQHHGGTGAPGGAGGGGGGSGGFNLPLN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MATPGSEPQPFVPALSVATLHPLHHPHHHHHHHQHHGGTGAPGGAGGGGGGSGGFNLPLN
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KA1 RGLERALEEAANSGGLNLSARKLKEFPRTAAPGHDLSDTVQADLSKNRLVEVPMELCHFV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RGLERALEEAANSGGLNLSARKLKEFPRTAAPGHDLSDTVQADLSKNRLVEVPMELCHFV
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KA1 SLEILNLYHNCIRVIPEAIVNLQMLTYLNLSRNQLSALPACLCGLPLKVLIASNNKLGSL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SLEILNLYHNCIRVIPEAIVNLQMLTYLNLSRNQLSALPACLCGLPLKVLIASNNKLGSL
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KA1 PEEIGQLKQLMELDVSCNEITALPQQIGQLKSLRELNVRRNYLKVLPQELVDLPLVKFDF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PEEIGQLKQLMELDVSCNEITALPQQIGQLKSLRELNVRRNYLKVLPQELVDLPLVKFDF
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KA1 SCNKVLVIPICFREMKQLQVLLLENNPLQSPPAQICTKGKVHIFKYLSIQACQIKTADSL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SCNKVLVIPICFREMKQLQVLLLENNPLQSPPAQICTKGKVHIFKYLSIQACQIKTADSL
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KA1 YLHTMERPHLHQHVEDGKKDSDSGVGSDNGDKRLSATEPSDEDTVSLNVPMSNIMEEEQI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 YLHTMERPHLHQHVEDGKKDSDSGVGSDNGDKRLSATEPSDEDTVSLNVPMSNIMEEEQI
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KA1 IKEDSCHRLSPVKGEFHQEFQPEPSLLGDSTNSGEERDQFTDRADGLHSEFMNYKARAED
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IKEDSCHRLSPVKGEFHQEFQPEPSLLGDSTNSGEERDQFTDRADGLHSEFMNYKARAED
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KA1 CEELLRIEEDVHWQTEGIISSSKDQDMDIAMIEQLREAVDLLQDPNGLSTDITERSVLNL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 CEELLRIEEDVHWQTEGIISSSKDQDMDIAMIEQLREAVDLLQDPNGLSTDITERSVLNL
              430       440       450       460       470       480

              490       500       510       520       530       540
pF1KA1 YPMGSAEALELQDSALNGQIQLETSPVCEVQSDLTLQSNGSQYSPNEIRENSPAVSPTTN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 YPMGSAEALELQDSALNGQIQLETSPVCEVQSDLTLQSNGSQYSPNEIRENSPAVSPTTN
              490       500       510       520       530       540

              550                                          560     
pF1KA1 STAPFGLKPRS-----------------------------------VFLRPQRNLESIDP
       :::::::::::                                   ::::::::::::::
NP_001 STAPFGLKPRSDPALILPPISFNTLTQAQTWDSSSYSVPSEGDSDNVFLRPQRNLESIDP
              550       560       570       580       590       600

         570       580       590       600       610       620     
pF1KA1 QFTIRRKMEQMREEKELVEQLRESIEMRLKVSLHEDLGAALMDGVVLCHLVNHIRPRSVA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QFTIRRKMEQMREEKELVEQLRESIEMRLKVSLHEDLGAALMDGVVLCHLVNHIRPRSVA
              610       620       630       640       650       660

         630       640       650       660       670       680     
pF1KA1 SIHVPSPAVPKLSMAKCRRNVENFLEACRKLGVPEADLCSPCDILQLDFRHIRKTVDTLL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SIHVPSPAVPKLSMAKCRRNVENFLEACRKLGVPEADLCSPCDILQLDFRHIRKTVDTLL
              670       680       690       700       710       720

         690       700       710       720        
pF1KA1 ALGEKAPPPTSALRSRDLIGFCLVHILFIVLVYITYHWNALSA
       ::::::::::::::::::::::::::::::::::::::::   
NP_001 ALGEKAPPPTSALRSRDLIGFCLVHILFIVLVYITYHWNALSA
              730       740       750       760   

>>XP_016875972 (OMIM: 610368) PREDICTED: leucine-rich re  (731 aa)
 initn: 4408 init1: 3672 opt: 3672  Z-score: 2763.6  bits: 522.0 E(85289): 3.4e-147
Smith-Waterman score: 4342; 94.1% identity (94.2% similar) in 706 aa overlap (1-671:1-706)

               10        20        30        40        50        60
pF1KA1 MATPGSEPQPFVPALSVATLHPLHHPHHHHHHHQHHGGTGAPGGAGGGGGGSGGFNLPLN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MATPGSEPQPFVPALSVATLHPLHHPHHHHHHHQHHGGTGAPGGAGGGGGGSGGFNLPLN
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KA1 RGLERALEEAANSGGLNLSARKLKEFPRTAAPGHDLSDTVQADLSKNRLVEVPMELCHFV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RGLERALEEAANSGGLNLSARKLKEFPRTAAPGHDLSDTVQADLSKNRLVEVPMELCHFV
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KA1 SLEILNLYHNCIRVIPEAIVNLQMLTYLNLSRNQLSALPACLCGLPLKVLIASNNKLGSL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SLEILNLYHNCIRVIPEAIVNLQMLTYLNLSRNQLSALPACLCGLPLKVLIASNNKLGSL
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KA1 PEEIGQLKQLMELDVSCNEITALPQQIGQLKSLRELNVRRNYLKVLPQELVDLPLVKFDF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::: ::::::
XP_016 PEEIGQLKQLMELDVSCNEITALPQQIGQLKSLRELNVRRNYLKVLPQELVDLSLVKFDF
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KA1 SCNKVLVIPICFREMKQLQVLLLENNPLQSPPAQICTKGKVHIFKYLSIQACQIKTADSL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SCNKVLVIPICFREMKQLQVLLLENNPLQSPPAQICTKGKVHIFKYLSIQACQIKTADSL
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KA1 YLHTMERPHLHQHVEDGKKDSDSGVGSDNGDKRLSATEPSDEDTVSLNVPMSNIMEEEQI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 YLHTMERPHLHQHVEDGKKDSDSGVGSDNGDKRLSATEPSDEDTVSLNVPMSNIMEEEQI
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KA1 IKEDSCHRLSPVKGEFHQEFQPEPSLLGDSTNSGEERDQFTDRADGLHSEFMNYKARAED
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IKEDSCHRLSPVKGEFHQEFQPEPSLLGDSTNSGEERDQFTDRADGLHSEFMNYKARAED
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KA1 CEELLRIEEDVHWQTEGIISSSKDQDMDIAMIEQLREAVDLLQDPNGLSTDITERSVLNL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 CEELLRIEEDVHWQTEGIISSSKDQDMDIAMIEQLREAVDLLQDPNGLSTDITERSVLNL
              430       440       450       460       470       480

              490       500       510       520       530       540
pF1KA1 YPMGSAEALELQDSALNGQIQLETSPVCEVQSDLTLQSNGSQYSPNEIRENSPAVSPTTN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 YPMGSAEALELQDSALNGQIQLETSPVCEVQSDLTLQSNGSQYSPNEIRENSPAVSPTTN
              490       500       510       520       530       540

              550                                          560     
pF1KA1 STAPFGLKPRS-----------------------------------VFLRPQRNLESIDP
       :::::::::::                                   ::::::::::::::
XP_016 STAPFGLKPRSDPALILPPISFNTLTQAQTWDSSSYSVPSEGDSDNVFLRPQRNLESIDP
              550       560       570       580       590       600

         570       580       590       600       610       620     
pF1KA1 QFTIRRKMEQMREEKELVEQLRESIEMRLKVSLHEDLGAALMDGVVLCHLVNHIRPRSVA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QFTIRRKMEQMREEKELVEQLRESIEMRLKVSLHEDLGAALMDGVVLCHLVNHIRPRSVA
              610       620       630       640       650       660

         630       640       650       660       670       680     
pF1KA1 SIHVPSPAVPKLSMAKCRRNVENFLEACRKLGVPEADLCSPCDILQLDFRHIRKTVDTLL
       :::::::::::::::::::::::::::::::::::  :: :  ::.              
XP_016 SIHVPSPAVPKLSMAKCRRNVENFLEACRKLGVPEEKLCLPHHILEEKGLVKVGITIQAL
              670       680       690       700       710       720

         690       700       710       720        
pF1KA1 ALGEKAPPPTSALRSRDLIGFCLVHILFIVLVYITYHWNALSA
                                                  
XP_016 LDITVTKALFT                                
              730                                 

>>XP_016875973 (OMIM: 610368) PREDICTED: leucine-rich re  (477 aa)
 initn: 2699 init1: 1963 opt: 1963  Z-score: 1485.8  bits: 284.9 E(85289): 5.1e-76
Smith-Waterman score: 2633; 90.9% identity (91.2% similar) in 452 aa overlap (255-671:1-452)

          230       240       250       260       270       280    
pF1KA1 VLPQELVDLPLVKFDFSCNKVLVIPICFREMKQLQVLLLENNPLQSPPAQICTKGKVHIF
                                     ::::::::::::::::::::::::::::::
XP_016                               MKQLQVLLLENNPLQSPPAQICTKGKVHIF
                                             10        20        30

          290       300       310       320       330       340    
pF1KA1 KYLSIQACQIKTADSLYLHTMERPHLHQHVEDGKKDSDSGVGSDNGDKRLSATEPSDEDT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KYLSIQACQIKTADSLYLHTMERPHLHQHVEDGKKDSDSGVGSDNGDKRLSATEPSDEDT
               40        50        60        70        80        90

          350       360       370       380       390       400    
pF1KA1 VSLNVPMSNIMEEEQIIKEDSCHRLSPVKGEFHQEFQPEPSLLGDSTNSGEERDQFTDRA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VSLNVPMSNIMEEEQIIKEDSCHRLSPVKGEFHQEFQPEPSLLGDSTNSGEERDQFTDRA
              100       110       120       130       140       150

          410       420       430       440       450       460    
pF1KA1 DGLHSEFMNYKARAEDCEELLRIEEDVHWQTEGIISSSKDQDMDIAMIEQLREAVDLLQD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DGLHSEFMNYKARAEDCEELLRIEEDVHWQTEGIISSSKDQDMDIAMIEQLREAVDLLQD
              160       170       180       190       200       210

          470       480       490       500       510       520    
pF1KA1 PNGLSTDITERSVLNLYPMGSAEALELQDSALNGQIQLETSPVCEVQSDLTLQSNGSQYS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PNGLSTDITERSVLNLYPMGSAEALELQDSALNGQIQLETSPVCEVQSDLTLQSNGSQYS
              220       230       240       250       260       270

          530       540       550                                  
pF1KA1 PNEIRENSPAVSPTTNSTAPFGLKPRS---------------------------------
       :::::::::::::::::::::::::::                                 
XP_016 PNEIRENSPAVSPTTNSTAPFGLKPRSDPALILPPISFNTLTQAQTWDSSSYSVPSEGDS
              280       290       300       310       320       330

               560       570       580       590       600         
pF1KA1 --VFLRPQRNLESIDPQFTIRRKMEQMREEKELVEQLRESIEMRLKVSLHEDLGAALMDG
         ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DNVFLRPQRNLESIDPQFTIRRKMEQMREEKELVEQLRESIEMRLKVSLHEDLGAALMDG
              340       350       360       370       380       390

     610       620       630       640       650       660         
pF1KA1 VVLCHLVNHIRPRSVASIHVPSPAVPKLSMAKCRRNVENFLEACRKLGVPEADLCSPCDI
       :::::::::::::::::::::::::::::::::::::::::::::::::::  :: :  :
XP_016 VVLCHLVNHIRPRSVASIHVPSPAVPKLSMAKCRRNVENFLEACRKLGVPEEKLCLPHHI
              400       410       420       430       440       450

     670       680       690       700       710       720        
pF1KA1 LQLDFRHIRKTVDTLLALGEKAPPPTSALRSRDLIGFCLVHILFIVLVYITYHWNALSA
       :.                                                         
XP_016 LEEKGLVKVGITIQALLDITVTKALFT                                
              460       470                                       

>>NP_036557 (OMIM: 179555) ras suppressor protein 1 isof  (277 aa)
 initn: 528 init1: 165 opt: 355  Z-score: 284.3  bits: 61.8 E(85289): 4.3e-09
Smith-Waterman score: 355; 31.9% identity (61.9% similar) in 273 aa overlap (59-322:1-262)

       30        40        50        60        70          80      
pF1KA1 HHHHHQHHGGTGAPGGAGGGGGGSGGFNLPLNRGLERALEEA--ANSGGLNLSARKLKEF
                                     ....:.. .::.   :.  ...: : ....
NP_036                               MSKSLKKLVEESREKNQPEVDMSDRGISNM
                                             10        20        30

         90       100       110       120       130       140      
pF1KA1 PRTAAPGHDLSDTVQADLSKNRLVEVPMELCHFVSLEILNLYHNCIRVIPEAIVNLQMLT
         . .    ::  .:  ::.:.:. :: .. .. .::.::...: :. .:  : .:: : 
NP_036 LDVNGL-FTLSHITQLVLSHNKLTMVPPNIAELKNLEVLNFFNNQIEELPTQISSLQKLK
                40        50        60        70        80         

        150       160        170         180       190       200   
pF1KA1 YLNLSRNQLSALPACLCGLP-LKVLIASNNKLG--SLPEEIGQLKQLMELDVSCNEITAL
       .:::. :.:..::  . .:: :.::  . :.:.  ::: ..  :  :  : .: :..  :
NP_036 HLNLGMNRLNTLPRGFGSLPALEVLDLTYNNLSENSLPGNFFYLTTLRALYLSDNDFEIL
      90       100       110       120       130       140         

           210       220       230        240       250            
pF1KA1 PQQIGQLKSLRELNVRRNYLKVLPQELVDLPLVK-FDFSCNKVLVIPICFREMK---QLQ
       : .::.: .:. :..: : :  ::.:. .:  .: . .. :.. :.:  . ..    : :
NP_036 PPDIGKLTKLQILSLRDNDLISLPKEIGELTQLKELHIQGNRLTVLPPELGNLDLTGQKQ
     150       160       170       180       190       200         

     260       270       280       290       300       310         
pF1KA1 VLLLENNPLQSPPAQICTKGKVHIFKYLSIQACQIKTADSLYLHTMERPHLHQHVEDGKK
       :.  ::::  .: :.    :  :.:.:       :..    ::.     :.. . :  ::
NP_036 VFKAENNPWVTPIADQFQLGVSHVFEY-------IRSETYKYLYGR---HMQANPEPPKK
     210       220       230              240          250         

     320       330       340       350       360       370         
pF1KA1 DSDSGVGSDNGDKRLSATEPSDEDTVSLNVPMSNIMEEEQIIKEDSCHRLSPVKGEFHQE
       ..:                                                         
NP_036 NNDKSKKISRKPLAAKNR                                          
     260       270                                                 

>>XP_011542154 (OMIM: 605352) PREDICTED: malignant fibro  (1003 aa)
 initn: 368 init1: 160 opt: 343  Z-score: 267.6  bits: 60.6 E(85289): 3.6e-08
Smith-Waterman score: 343; 33.4% identity (59.5% similar) in 296 aa overlap (40-326:38-319)

      10        20        30        40           50        60      
pF1KA1 PFVPALSVATLHPLHHPHHHHHHHQHHGGTGAPGGAGGGG---GGSGGFNLPLNRGLERA
                                     ::  :::. .    .:  . :: : :  .:
XP_011 NLKTARLWRDAALRARKLRSNLRQLTLTAAGACPGAGADALESPASPQLVLPANLGDIEA
        10        20        30        40        50        60       

         70        80        90       100       110          120   
pF1KA1 LEEAANSGGLNLSARKLKEFPRTAAPGHDLSDTVQADLSKNRLVEVP---MELCHFVSLE
       :         ::.   :.: :.    :  :..     : .::....:    :: :   : 
XP_011 L---------NLGNNGLEEVPEGL--GSALGSLRVLVLRRNRFARLPPAVAELGHH--LT
                 70        80          90       100       110      

           130       140        150       160        170       180 
pF1KA1 ILNLYHNCIRVIPEAIVN-LQMLTYLNLSRNQLSALPACLCGLP-LKVLIASNNKLGSLP
        :.. :: . ..   .:. :. :  ::::.::: :::: : .:  :. : .: :.:. ::
XP_011 ELDVSHNRLTALGAEVVSALRELRKLNLSHNQLPALPAQLGALAHLEELDVSFNRLAHLP
          120       130       140       150       160       170    

             190       200       210       220       230       240 
pF1KA1 EEIGQLKQLMELDVSCNEITALPQQIGQLKSLRELNVRRNYLKVLPQELVDLPLVKFDF-
       . .. :..:  :::. :..::.:.:. :: .:.::.:  : :. ::...  :  .:. . 
XP_011 DSLSCLSRLRTLDVDHNQLTAFPRQLLQLVALEELDVSSNRLRGLPEDISALRALKILWL
          180       190       200       210       220       230    

              250       260       270       280       290       300
pF1KA1 SCNKVLVIPICFREMKQLQVLLLENNPLQSPPAQICTKGKVHIFKYLSIQACQIKTADSL
       :  .. ..:  : :. .:. :.:.:: ::. :::.    ...... :: .  .   :  :
XP_011 SGAELGTLPAGFCELASLESLMLDNNGLQALPAQFSCLQRLKMLN-LSSNLFEEFPAALL
          240       250       260       270        280       290   

              310       320       330       340       350       360
pF1KA1 YLHTMERPHLHQHVEDGKKDSDSGVGSDNGDKRLSATEPSDEDTVSLNVPMSNIMEEEQI
        :  .:. .: ..   .  .  ::.:                                  
XP_011 PLAGLEELYLSRNQLTSVPSLISGLGRLLTLWLDNNRIRYLPDSIVELTGLEELVLQGNQ
           300       310       320       330       340       350   

>>NP_004216 (OMIM: 605352) malignant fibrous histiocytom  (1052 aa)
 initn: 368 init1: 160 opt: 343  Z-score: 267.3  bits: 60.6 E(85289): 3.8e-08
Smith-Waterman score: 343; 33.4% identity (59.5% similar) in 296 aa overlap (40-326:38-319)

      10        20        30        40           50        60      
pF1KA1 PFVPALSVATLHPLHHPHHHHHHHQHHGGTGAPGGAGGGG---GGSGGFNLPLNRGLERA
                                     ::  :::. .    .:  . :: : :  .:
NP_004 NLKTARLWRDAALRARKLRSNLRQLTLTAAGACPGAGADALESPASPQLVLPANLGDIEA
        10        20        30        40        50        60       

         70        80        90       100       110          120   
pF1KA1 LEEAANSGGLNLSARKLKEFPRTAAPGHDLSDTVQADLSKNRLVEVP---MELCHFVSLE
       :         ::.   :.: :.    :  :..     : .::....:    :: :   : 
NP_004 L---------NLGNNGLEEVPEGL--GSALGSLRVLVLRRNRFARLPPAVAELGHH--LT
                 70        80          90       100       110      

           130       140        150       160        170       180 
pF1KA1 ILNLYHNCIRVIPEAIVN-LQMLTYLNLSRNQLSALPACLCGLP-LKVLIASNNKLGSLP
        :.. :: . ..   .:. :. :  ::::.::: :::: : .:  :. : .: :.:. ::
NP_004 ELDVSHNRLTALGAEVVSALRELRKLNLSHNQLPALPAQLGALAHLEELDVSFNRLAHLP
          120       130       140       150       160       170    

             190       200       210       220       230       240 
pF1KA1 EEIGQLKQLMELDVSCNEITALPQQIGQLKSLRELNVRRNYLKVLPQELVDLPLVKFDF-
       . .. :..:  :::. :..::.:.:. :: .:.::.:  : :. ::...  :  .:. . 
NP_004 DSLSCLSRLRTLDVDHNQLTAFPRQLLQLVALEELDVSSNRLRGLPEDISALRALKILWL
          180       190       200       210       220       230    

              250       260       270       280       290       300
pF1KA1 SCNKVLVIPICFREMKQLQVLLLENNPLQSPPAQICTKGKVHIFKYLSIQACQIKTADSL
       :  .. ..:  : :. .:. :.:.:: ::. :::.    ...... :: .  .   :  :
NP_004 SGAELGTLPAGFCELASLESLMLDNNGLQALPAQFSCLQRLKMLN-LSSNLFEEFPAALL
          240       250       260       270        280       290   

              310       320       330       340       350       360
pF1KA1 YLHTMERPHLHQHVEDGKKDSDSGVGSDNGDKRLSATEPSDEDTVSLNVPMSNIMEEEQI
        :  .:. .: ..   .  .  ::.:                                  
NP_004 PLAGLEELYLSRNQLTSVPSLISGLGRLLTLWLDNNRIRYLPDSIVELTGLEELVLQGNQ
           300       310       320       330       340       350   

>>NP_665894 (OMIM: 605247) p53-induced protein with a de  (893 aa)
 initn: 260 init1: 165 opt: 316  Z-score: 248.0  bits: 56.8 E(85289): 4.5e-07
Smith-Waterman score: 316; 36.3% identity (64.8% similar) in 182 aa overlap (96-273:124-302)

          70        80        90       100       110       120     
pF1KA1 ALEEAANSGGLNLSARKLKEFPRTAAPGHDLSDTVQADLSKNRLVEVPMELCHFVSLEIL
                                     :.  .. ::: : :  .:  . .. .:  :
NP_665 SLVLKGGQRRDTLGACLRGALTNLPAGLSGLAHLAHLDLSFNSLETLPACVLQMRGLGAL
           100       110       120       130       140       150   

         130       140       150       160        170       180    
pF1KA1 NLYHNCIRVIPEAIVNLQMLTYLNLSRNQLSALPACLCGLP-LKVLIASNNKLGSLPEEI
        : :::.  .:::.  :  ::.:....:.:..::  : .:  :. :  :.: : .:: ::
NP_665 LLSHNCLSELPEALGALPALTFLTVTHNRLQTLPPALGALSTLQRLDLSQNLLDTLPPEI
           160       170       180       190       200       210   

          190       200       210       220       230        240   
pF1KA1 GQLKQLMELDVSCNEITALPQQIGQLKSLRELNVRRNYLKVLPQELVDLPLV-KFDFSCN
       : : .:.::... :.. .:: ... :.::: : .. : :  .: .:. :::. ..:.  :
NP_665 GGLGSLLELNLASNRLQSLPASLAGLRSLRLLVLHSNLLASVPADLARLPLLTRLDLRDN
           220       230       240       250       260       270   

           250       260         270       280       290       300 
pF1KA1 KVLVIPICFREMKQLQVLLLENNPL--QSPPAQICTKGKVHIFKYLSIQACQIKTADSLY
       ..  .:    :. .   . :..:::   :: :                            
NP_665 QLRDLPP---ELLDAPFVRLQGNPLGEASPDAPSSPVAALIPEMPRLFLTSDLDSFPVTP
           280          290       300       310       320       330

             310       320       330       340       350       360 
pF1KA1 LHTMERPHLHQHVEDGKKDSDSGVGSDNGDKRLSATEPSDEDTVSLNVPMSNIMEEEQII
                                                                   
NP_665 QGCSVTLACGVRLQFPAGATATPITIRYRLLLPEPGLVPLGPHDALLSHVLELQPHGVAF
              340       350       360       370       380       390

>>XP_011518513 (OMIM: 605247) PREDICTED: p53-induced dea  (893 aa)
 initn: 260 init1: 165 opt: 316  Z-score: 248.0  bits: 56.8 E(85289): 4.5e-07
Smith-Waterman score: 316; 36.3% identity (64.8% similar) in 182 aa overlap (96-273:124-302)

          70        80        90       100       110       120     
pF1KA1 ALEEAANSGGLNLSARKLKEFPRTAAPGHDLSDTVQADLSKNRLVEVPMELCHFVSLEIL
                                     :.  .. ::: : :  .:  . .. .:  :
XP_011 SLVLKGGQRRDTLGACLRGALTNLPAGLSGLAHLAHLDLSFNSLETLPACVLQMRGLGAL
           100       110       120       130       140       150   

         130       140       150       160        170       180    
pF1KA1 NLYHNCIRVIPEAIVNLQMLTYLNLSRNQLSALPACLCGLP-LKVLIASNNKLGSLPEEI
        : :::.  .:::.  :  ::.:....:.:..::  : .:  :. :  :.: : .:: ::
XP_011 LLSHNCLSELPEALGALPALTFLTVTHNRLQTLPPALGALSTLQRLDLSQNLLDTLPPEI
           160       170       180       190       200       210   

          190       200       210       220       230        240   
pF1KA1 GQLKQLMELDVSCNEITALPQQIGQLKSLRELNVRRNYLKVLPQELVDLPLV-KFDFSCN
       : : .:.::... :.. .:: ... :.::: : .. : :  .: .:. :::. ..:.  :
XP_011 GGLGSLLELNLASNRLQSLPASLAGLRSLRLLVLHSNLLASVPADLARLPLLTRLDLRDN
           220       230       240       250       260       270   

           250       260         270       280       290       300 
pF1KA1 KVLVIPICFREMKQLQVLLLENNPL--QSPPAQICTKGKVHIFKYLSIQACQIKTADSLY
       ..  .:    :. .   . :..:::   :: :                            
XP_011 QLRDLPP---ELLDAPFVRLQGNPLGEASPDAPSSPVAALIPEMPRLFLTSDLDSFPVTP
           280          290       300       310       320       330

             310       320       330       340       350       360 
pF1KA1 LHTMERPHLHQHVEDGKKDSDSGVGSDNGDKRLSATEPSDEDTVSLNVPMSNIMEEEQII
                                                                   
XP_011 QGCSVTLACGVRLQFPAGATATPITIRYRLLLPEPGLVPLGPHDALLSHVLELQPHGVAF
              340       350       360       370       380       390




728 residues in 1 query   sequences
60827320 residues in 85289 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Wed Nov  2 20:16:17 2016 done: Wed Nov  2 20:16:19 2016
 Total Scan time: 12.000 Total Display time:  0.150

Function used was FASTA [36.3.4 Apr, 2011]
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