Result of FASTA (omim) for pF1KA0985
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KA0985, 694 aa
  1>>>pF1KA0985 694 - 694 aa - 694 aa
Library: /omim/omim.rfq.tfa
  60827320 residues in 85289 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 14.5430+/-0.000476; mu= -21.4936+/- 0.030
 mean_var=603.1288+/-126.001, 0's: 0 Z-trim(124.5): 166  B-trim: 966 in 2/58
 Lambda= 0.052224
 statistics sampled from 46071 (46269) to 46071 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.81), E-opt: 0.2 (0.542), width:  16
 Scan time: 12.060

The best scores are:                                      opt bits E(85289)
XP_011536350 (OMIM: 612159) PREDICTED: rabphilin-3 ( 694) 4813 377.7 8.4e-104
NP_001137326 (OMIM: 612159) rabphilin-3A isoform 1 ( 694) 4813 377.7 8.4e-104
NP_055769 (OMIM: 612159) rabphilin-3A isoform 2 [H ( 690) 4763 373.9 1.1e-102
XP_016874523 (OMIM: 612159) PREDICTED: rabphilin-3 ( 346) 2334 190.7 8.3e-48
XP_016879265 (OMIM: 604567) PREDICTED: double C2-l ( 400) 1402 120.5 1.3e-26
XP_016879266 (OMIM: 604567) PREDICTED: double C2-l ( 400) 1402 120.5 1.3e-26
NP_001268997 (OMIM: 604567) double C2-like domain- ( 400) 1402 120.5 1.3e-26
NP_003577 (OMIM: 604567) double C2-like domain-con ( 400) 1402 120.5 1.3e-26
NP_001268992 (OMIM: 604567) double C2-like domain- ( 400) 1402 120.5 1.3e-26
NP_001268991 (OMIM: 604567) double C2-like domain- ( 400) 1402 120.5 1.3e-26
XP_011544277 (OMIM: 604567) PREDICTED: double C2-l ( 400) 1402 120.5 1.3e-26
XP_016879267 (OMIM: 604567) PREDICTED: double C2-l ( 282) 1200 105.1 3.7e-22
XP_016880716 (OMIM: 604568) PREDICTED: double C2-l ( 340)  891 81.9 4.4e-15
NP_003576 (OMIM: 604568) double C2-like domain-con ( 412)  890 81.9 5.3e-15
XP_011533665 (OMIM: 604568) PREDICTED: double C2-l ( 387)  788 74.2   1e-12
XP_011533666 (OMIM: 604881) PREDICTED: rab effecto ( 321)  750 71.3 6.6e-12
XP_011533667 (OMIM: 604881) PREDICTED: rab effecto ( 321)  750 71.3 6.6e-12
XP_011533668 (OMIM: 604881) PREDICTED: rab effecto ( 321)  750 71.3 6.6e-12
NP_008918 (OMIM: 604881) rab effector Noc2 isoform ( 315)  746 71.0   8e-12
XP_011533669 (OMIM: 604881) PREDICTED: rab effecto ( 315)  746 71.0   8e-12
NP_001177340 (OMIM: 604881) rab effector Noc2 isof ( 315)  746 71.0   8e-12
XP_016880857 (OMIM: 604881) PREDICTED: rab effecto ( 253)  718 68.8 2.9e-11
XP_016880856 (OMIM: 604881) PREDICTED: rab effecto ( 259)  696 67.1 9.4e-11
XP_016880860 (OMIM: 604881) PREDICTED: rab effecto ( 161)  560 56.7   8e-08
XP_011533671 (OMIM: 604881) PREDICTED: rab effecto ( 239)  491 51.7   4e-06
XP_016880858 (OMIM: 604881) PREDICTED: rab effecto ( 239)  491 51.7   4e-06
XP_016880859 (OMIM: 604881) PREDICTED: rab effecto ( 233)  487 51.4 4.8e-06
NP_001177342 (OMIM: 604881) rab effector Noc2 isof ( 286)  466 49.8 1.7e-05
NP_001177341 (OMIM: 604881) rab effector Noc2 isof ( 286)  466 49.8 1.7e-05
XP_011533670 (OMIM: 604881) PREDICTED: rab effecto ( 286)  466 49.8 1.7e-05
XP_016877187 (OMIM: 610950) PREDICTED: synaptotagm ( 339)  381 43.5  0.0016
XP_011535531 (OMIM: 610950) PREDICTED: synaptotagm ( 424)  381 43.6  0.0019
XP_016877185 (OMIM: 610950) PREDICTED: synaptotagm ( 462)  381 43.6   0.002
XP_011535530 (OMIM: 610950) PREDICTED: synaptotagm ( 464)  381 43.6   0.002
XP_011535529 (OMIM: 610950) PREDICTED: synaptotagm ( 505)  381 43.6  0.0022
XP_011535526 (OMIM: 610950) PREDICTED: synaptotagm ( 533)  381 43.7  0.0023
XP_011535527 (OMIM: 610950) PREDICTED: synaptotagm ( 533)  381 43.7  0.0023
XP_011535525 (OMIM: 610950) PREDICTED: synaptotagm ( 535)  381 43.7  0.0023
XP_011543638 (OMIM: 604146) PREDICTED: synaptotagm ( 651)  383 43.9  0.0024
XP_016877184 (OMIM: 610950) PREDICTED: synaptotagm ( 645)  381 43.7  0.0026
XP_006720335 (OMIM: 610950) PREDICTED: synaptotagm ( 645)  381 43.7  0.0026
XP_016877182 (OMIM: 610950) PREDICTED: synaptotagm ( 645)  381 43.7  0.0026
NP_114120 (OMIM: 610950) synaptotagmin-16 [Homo sa ( 645)  381 43.7  0.0026
XP_011535521 (OMIM: 610950) PREDICTED: synaptotagm ( 645)  381 43.7  0.0026
XP_016877183 (OMIM: 610950) PREDICTED: synaptotagm ( 645)  381 43.7  0.0026
NP_001257734 (OMIM: 607718) synaptotagmin-6 [Homo  ( 425)  367 42.5   0.004
NP_995320 (OMIM: 607718) synaptotagmin-6 [Homo sap ( 425)  367 42.5   0.004
XP_016855860 (OMIM: 607718) PREDICTED: synaptotagm ( 443)  367 42.5  0.0041
NP_001238994 (OMIM: 604146) synaptotagmin-7 isofor ( 478)  367 42.6  0.0043
XP_011543642 (OMIM: 604146) PREDICTED: synaptotagm ( 484)  367 42.6  0.0044


>>XP_011536350 (OMIM: 612159) PREDICTED: rabphilin-3A is  (694 aa)
 initn: 4813 init1: 4813 opt: 4813  Z-score: 1984.6  bits: 377.7 E(85289): 8.4e-104
Smith-Waterman score: 4813; 100.0% identity (100.0% similar) in 694 aa overlap (1-694:1-694)

               10        20        30        40        50        60
pF1KA0 MTDTVFSNSSNRWMYPSDRPLQSNDKEQLQAGWSVHPGGQPDRQRKQEELTDEEKEIINR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MTDTVFSNSSNRWMYPSDRPLQSNDKEQLQAGWSVHPGGQPDRQRKQEELTDEEKEIINR
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KA0 VIARAEKMEEMEQERIGRLVDRLENMRKNVAGDGVNRCILCGEQLGMLGSACVVCEDCKK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VIARAEKMEEMEQERIGRLVDRLENMRKNVAGDGVNRCILCGEQLGMLGSACVVCEDCKK
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KA0 NVCTKCGVETNNRLHSVWLCKICIEQREVWKRSGAWFFKGFPKQVLPQPMPIKKTKPQQP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NVCTKCGVETNNRLHSVWLCKICIEQREVWKRSGAWFFKGFPKQVLPQPMPIKKTKPQQP
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KA0 VSEPAAPEQPAPEPKHPARAPARGDSEDRRGPGQKTGPDPASAPGRGNYGPPVRRASEAR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VSEPAAPEQPAPEPKHPARAPARGDSEDRRGPGQKTGPDPASAPGRGNYGPPVRRASEAR
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KA0 MSSSSRDSESWDHSGGAGDSSRSPAGLRRANSVQASRPAPGSVQSPAPPQPGQPGTPGGS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MSSSSRDSESWDHSGGAGDSSRSPAGLRRANSVQASRPAPGSVQSPAPPQPGQPGTPGGS
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KA0 RPGPGPAGRFPDQKPEVAPSDPGTTAPPREERTGGVGGYPAVGAREDRMSHPSGPYSQAS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RPGPGPAGRFPDQKPEVAPSDPGTTAPPREERTGGVGGYPAVGAREDRMSHPSGPYSQAS
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KA0 AAAPQPAAARQPPPPEEEEEEANSYDSDEATTLGALEFSLLYDQDNSSLQCTIIKAKGLK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AAAPQPAAARQPPPPEEEEEEANSYDSDEATTLGALEFSLLYDQDNSSLQCTIIKAKGLK
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KA0 PMDSNGLADPYVKLHLLPGASKSNKLRTKTLRNTRNPIWNETLVYHGITDEDMQRKTLRI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PMDSNGLADPYVKLHLLPGASKSNKLRTKTLRNTRNPIWNETLVYHGITDEDMQRKTLRI
              430       440       450       460       470       480

              490       500       510       520       530       540
pF1KA0 SVCDEDKFGHNEFIGETRFSLKKLKPNQRKNFNICLERVIPMKRAGTTGSARGMALYEEE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SVCDEDKFGHNEFIGETRFSLKKLKPNQRKNFNICLERVIPMKRAGTTGSARGMALYEEE
              490       500       510       520       530       540

              550       560       570       580       590       600
pF1KA0 QVERVGDIEERGKILVSLMYSTQQGGLIVGIIRCVHLAAMDANGYSDPFVKLWLKPDMGK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QVERVGDIEERGKILVSLMYSTQQGGLIVGIIRCVHLAAMDANGYSDPFVKLWLKPDMGK
              550       560       570       580       590       600

              610       620       630       640       650       660
pF1KA0 KAKHKTQIKKKTLNPEFNEEFFYDIKHSDLAKKSLDISVWDYDIGKSNDYIGGCQLGISA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KAKHKTQIKKKTLNPEFNEEFFYDIKHSDLAKKSLDISVWDYDIGKSNDYIGGCQLGISA
              610       620       630       640       650       660

              670       680       690    
pF1KA0 KGERLKHWYECLKNKDKKIERWHQLQNENHVSSD
       ::::::::::::::::::::::::::::::::::
XP_011 KGERLKHWYECLKNKDKKIERWHQLQNENHVSSD
              670       680       690    

>>NP_001137326 (OMIM: 612159) rabphilin-3A isoform 1 [Ho  (694 aa)
 initn: 4813 init1: 4813 opt: 4813  Z-score: 1984.6  bits: 377.7 E(85289): 8.4e-104
Smith-Waterman score: 4813; 100.0% identity (100.0% similar) in 694 aa overlap (1-694:1-694)

               10        20        30        40        50        60
pF1KA0 MTDTVFSNSSNRWMYPSDRPLQSNDKEQLQAGWSVHPGGQPDRQRKQEELTDEEKEIINR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MTDTVFSNSSNRWMYPSDRPLQSNDKEQLQAGWSVHPGGQPDRQRKQEELTDEEKEIINR
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KA0 VIARAEKMEEMEQERIGRLVDRLENMRKNVAGDGVNRCILCGEQLGMLGSACVVCEDCKK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VIARAEKMEEMEQERIGRLVDRLENMRKNVAGDGVNRCILCGEQLGMLGSACVVCEDCKK
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KA0 NVCTKCGVETNNRLHSVWLCKICIEQREVWKRSGAWFFKGFPKQVLPQPMPIKKTKPQQP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NVCTKCGVETNNRLHSVWLCKICIEQREVWKRSGAWFFKGFPKQVLPQPMPIKKTKPQQP
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KA0 VSEPAAPEQPAPEPKHPARAPARGDSEDRRGPGQKTGPDPASAPGRGNYGPPVRRASEAR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VSEPAAPEQPAPEPKHPARAPARGDSEDRRGPGQKTGPDPASAPGRGNYGPPVRRASEAR
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KA0 MSSSSRDSESWDHSGGAGDSSRSPAGLRRANSVQASRPAPGSVQSPAPPQPGQPGTPGGS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MSSSSRDSESWDHSGGAGDSSRSPAGLRRANSVQASRPAPGSVQSPAPPQPGQPGTPGGS
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KA0 RPGPGPAGRFPDQKPEVAPSDPGTTAPPREERTGGVGGYPAVGAREDRMSHPSGPYSQAS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RPGPGPAGRFPDQKPEVAPSDPGTTAPPREERTGGVGGYPAVGAREDRMSHPSGPYSQAS
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KA0 AAAPQPAAARQPPPPEEEEEEANSYDSDEATTLGALEFSLLYDQDNSSLQCTIIKAKGLK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AAAPQPAAARQPPPPEEEEEEANSYDSDEATTLGALEFSLLYDQDNSSLQCTIIKAKGLK
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KA0 PMDSNGLADPYVKLHLLPGASKSNKLRTKTLRNTRNPIWNETLVYHGITDEDMQRKTLRI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PMDSNGLADPYVKLHLLPGASKSNKLRTKTLRNTRNPIWNETLVYHGITDEDMQRKTLRI
              430       440       450       460       470       480

              490       500       510       520       530       540
pF1KA0 SVCDEDKFGHNEFIGETRFSLKKLKPNQRKNFNICLERVIPMKRAGTTGSARGMALYEEE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SVCDEDKFGHNEFIGETRFSLKKLKPNQRKNFNICLERVIPMKRAGTTGSARGMALYEEE
              490       500       510       520       530       540

              550       560       570       580       590       600
pF1KA0 QVERVGDIEERGKILVSLMYSTQQGGLIVGIIRCVHLAAMDANGYSDPFVKLWLKPDMGK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QVERVGDIEERGKILVSLMYSTQQGGLIVGIIRCVHLAAMDANGYSDPFVKLWLKPDMGK
              550       560       570       580       590       600

              610       620       630       640       650       660
pF1KA0 KAKHKTQIKKKTLNPEFNEEFFYDIKHSDLAKKSLDISVWDYDIGKSNDYIGGCQLGISA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KAKHKTQIKKKTLNPEFNEEFFYDIKHSDLAKKSLDISVWDYDIGKSNDYIGGCQLGISA
              610       620       630       640       650       660

              670       680       690    
pF1KA0 KGERLKHWYECLKNKDKKIERWHQLQNENHVSSD
       ::::::::::::::::::::::::::::::::::
NP_001 KGERLKHWYECLKNKDKKIERWHQLQNENHVSSD
              670       680       690    

>>NP_055769 (OMIM: 612159) rabphilin-3A isoform 2 [Homo   (690 aa)
 initn: 4621 init1: 4621 opt: 4763  Z-score: 1964.2  bits: 373.9 E(85289): 1.1e-102
Smith-Waterman score: 4763; 99.3% identity (99.4% similar) in 694 aa overlap (1-694:1-690)

               10        20        30        40        50        60
pF1KA0 MTDTVFSNSSNRWMYPSDRPLQSNDKEQLQAGWSVHPGGQPDRQRKQEELTDEEKEIINR
       :::::::::::::::::::::::    .::::::::::::::::::::::::::::::::
NP_055 MTDTVFSNSSNRWMYPSDRPLQS----KLQAGWSVHPGGQPDRQRKQEELTDEEKEIINR
               10        20            30        40        50      

               70        80        90       100       110       120
pF1KA0 VIARAEKMEEMEQERIGRLVDRLENMRKNVAGDGVNRCILCGEQLGMLGSACVVCEDCKK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 VIARAEKMEEMEQERIGRLVDRLENMRKNVAGDGVNRCILCGEQLGMLGSACVVCEDCKK
         60        70        80        90       100       110      

              130       140       150       160       170       180
pF1KA0 NVCTKCGVETNNRLHSVWLCKICIEQREVWKRSGAWFFKGFPKQVLPQPMPIKKTKPQQP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 NVCTKCGVETNNRLHSVWLCKICIEQREVWKRSGAWFFKGFPKQVLPQPMPIKKTKPQQP
        120       130       140       150       160       170      

              190       200       210       220       230       240
pF1KA0 VSEPAAPEQPAPEPKHPARAPARGDSEDRRGPGQKTGPDPASAPGRGNYGPPVRRASEAR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 VSEPAAPEQPAPEPKHPARAPARGDSEDRRGPGQKTGPDPASAPGRGNYGPPVRRASEAR
        180       190       200       210       220       230      

              250       260       270       280       290       300
pF1KA0 MSSSSRDSESWDHSGGAGDSSRSPAGLRRANSVQASRPAPGSVQSPAPPQPGQPGTPGGS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 MSSSSRDSESWDHSGGAGDSSRSPAGLRRANSVQASRPAPGSVQSPAPPQPGQPGTPGGS
        240       250       260       270       280       290      

              310       320       330       340       350       360
pF1KA0 RPGPGPAGRFPDQKPEVAPSDPGTTAPPREERTGGVGGYPAVGAREDRMSHPSGPYSQAS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 RPGPGPAGRFPDQKPEVAPSDPGTTAPPREERTGGVGGYPAVGAREDRMSHPSGPYSQAS
        300       310       320       330       340       350      

              370       380       390       400       410       420
pF1KA0 AAAPQPAAARQPPPPEEEEEEANSYDSDEATTLGALEFSLLYDQDNSSLQCTIIKAKGLK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 AAAPQPAAARQPPPPEEEEEEANSYDSDEATTLGALEFSLLYDQDNSSLQCTIIKAKGLK
        360       370       380       390       400       410      

              430       440       450       460       470       480
pF1KA0 PMDSNGLADPYVKLHLLPGASKSNKLRTKTLRNTRNPIWNETLVYHGITDEDMQRKTLRI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 PMDSNGLADPYVKLHLLPGASKSNKLRTKTLRNTRNPIWNETLVYHGITDEDMQRKTLRI
        420       430       440       450       460       470      

              490       500       510       520       530       540
pF1KA0 SVCDEDKFGHNEFIGETRFSLKKLKPNQRKNFNICLERVIPMKRAGTTGSARGMALYEEE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 SVCDEDKFGHNEFIGETRFSLKKLKPNQRKNFNICLERVIPMKRAGTTGSARGMALYEEE
        480       490       500       510       520       530      

              550       560       570       580       590       600
pF1KA0 QVERVGDIEERGKILVSLMYSTQQGGLIVGIIRCVHLAAMDANGYSDPFVKLWLKPDMGK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 QVERVGDIEERGKILVSLMYSTQQGGLIVGIIRCVHLAAMDANGYSDPFVKLWLKPDMGK
        540       550       560       570       580       590      

              610       620       630       640       650       660
pF1KA0 KAKHKTQIKKKTLNPEFNEEFFYDIKHSDLAKKSLDISVWDYDIGKSNDYIGGCQLGISA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 KAKHKTQIKKKTLNPEFNEEFFYDIKHSDLAKKSLDISVWDYDIGKSNDYIGGCQLGISA
        600       610       620       630       640       650      

              670       680       690    
pF1KA0 KGERLKHWYECLKNKDKKIERWHQLQNENHVSSD
       ::::::::::::::::::::::::::::::::::
NP_055 KGERLKHWYECLKNKDKKIERWHQLQNENHVSSD
        660       670       680       690

>>XP_016874523 (OMIM: 612159) PREDICTED: rabphilin-3A is  (346 aa)
 initn: 2334 init1: 2334 opt: 2334  Z-score: 979.3  bits: 190.7 E(85289): 8.3e-48
Smith-Waterman score: 2334; 100.0% identity (100.0% similar) in 346 aa overlap (349-694:1-346)

      320       330       340       350       360       370        
pF1KA0 PSDPGTTAPPREERTGGVGGYPAVGAREDRMSHPSGPYSQASAAAPQPAAARQPPPPEEE
                                     ::::::::::::::::::::::::::::::
XP_016                               MSHPSGPYSQASAAAPQPAAARQPPPPEEE
                                             10        20        30

      380       390       400       410       420       430        
pF1KA0 EEEANSYDSDEATTLGALEFSLLYDQDNSSLQCTIIKAKGLKPMDSNGLADPYVKLHLLP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EEEANSYDSDEATTLGALEFSLLYDQDNSSLQCTIIKAKGLKPMDSNGLADPYVKLHLLP
               40        50        60        70        80        90

      440       450       460       470       480       490        
pF1KA0 GASKSNKLRTKTLRNTRNPIWNETLVYHGITDEDMQRKTLRISVCDEDKFGHNEFIGETR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GASKSNKLRTKTLRNTRNPIWNETLVYHGITDEDMQRKTLRISVCDEDKFGHNEFIGETR
              100       110       120       130       140       150

      500       510       520       530       540       550        
pF1KA0 FSLKKLKPNQRKNFNICLERVIPMKRAGTTGSARGMALYEEEQVERVGDIEERGKILVSL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FSLKKLKPNQRKNFNICLERVIPMKRAGTTGSARGMALYEEEQVERVGDIEERGKILVSL
              160       170       180       190       200       210

      560       570       580       590       600       610        
pF1KA0 MYSTQQGGLIVGIIRCVHLAAMDANGYSDPFVKLWLKPDMGKKAKHKTQIKKKTLNPEFN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MYSTQQGGLIVGIIRCVHLAAMDANGYSDPFVKLWLKPDMGKKAKHKTQIKKKTLNPEFN
              220       230       240       250       260       270

      620       630       640       650       660       670        
pF1KA0 EEFFYDIKHSDLAKKSLDISVWDYDIGKSNDYIGGCQLGISAKGERLKHWYECLKNKDKK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EEFFYDIKHSDLAKKSLDISVWDYDIGKSNDYIGGCQLGISAKGERLKHWYECLKNKDKK
              280       290       300       310       320       330

      680       690    
pF1KA0 IERWHQLQNENHVSSD
       ::::::::::::::::
XP_016 IERWHQLQNENHVSSD
              340      

>>XP_016879265 (OMIM: 604567) PREDICTED: double C2-like   (400 aa)
 initn: 1398 init1: 708 opt: 1402  Z-score: 598.9  bits: 120.5 E(85289): 1.3e-26
Smith-Waterman score: 1407; 56.6% identity (75.6% similar) in 389 aa overlap (304-688:23-389)

           280       290       300       310       320       330   
pF1KA0 QASRPAPGSVQSPAPPQPGQPGTPGGSRPGPGPAGRFPDQKPEVAPSDPGTTAPPREERT
                                     :::  :   :  .  :  ::   :   :  
XP_016         MRGRRGDRMTINIQEHMAINVCPGPI-RPIRQISDYFPRGPG---P---EGG
                       10        20         30        40           

           340       350       360       370       380       390   
pF1KA0 GGVGGYPAVGAREDRMSHPSGPYSQASAAAPQPAAARQPPPPEEEEEEANSYDSDEATTL
       :: ::               .:   .  :   :::      ::.  : ..:::::.::.:
XP_016 GGGGG--------------EAPAHLVPLALAPPAALLGATTPEDGAE-VDSYDSDDATAL
          50                      60        70         80        90

           400       410       420       430       440       450   
pF1KA0 GALEFSLLYDQDNSSLQCTIIKAKGLKPMDSNGLADPYVKLHLLPGASKSNKLRTKTLRN
       :.:::.::::. . .:.:.:..:::::::: :::::::::::::::: :.:::.::: ::
XP_016 GTLEFDLLYDRASCTLHCSILRAKGLKPMDFNGLADPYVKLHLLPGACKANKLKTKTQRN
              100       110       120       130       140       150

           460       470       480       490       500       510   
pF1KA0 TRNPIWNETLVYHGITDEDMQRKTLRISVCDEDKFGHNEFIGETRFSLKKLKPNQRKNFN
       : ::.::: :.: ::::.:. .:.:::.::::::..::::::: :  :..:::.:.:.::
XP_016 TLNPVWNEDLTYSGITDDDITHKVLRIAVCDEDKLSHNEFIGEIRVPLRRLKPSQKKHFN
              160       170       180       190       200       210

           520       530          540        550       560         
pF1KA0 ICLERVIPMKRAGTTGSA-RGMALY--EEEQVER-VGDIEERGKILVSLMYSTQQGGLIV
       ::::: .:.   .. ..: ::.. :  : ::.:.  : .::::.::.:: ::... ::.:
XP_016 ICLERQVPLASPSSMSAALRGISCYLKELEQAEQGQGLLEERGRILLSLSYSSRRRGLLV
              220       230       240       250       260       270

     570       580       590       600       610       620         
pF1KA0 GIIRCVHLAAMDANGYSDPFVKLWLKPDMGKKAKHKTQIKKKTLNPEFNEEFFYDIKHSD
       ::.::.::::::.::::::.:: .:.::. ::.:::: .:::::::::::::::.:. : 
XP_016 GILRCAHLAAMDVNGYSDPYVKTYLRPDVDKKSKHKTCVKKKTLNPEFNEEFFYEIELST
              280       290       300       310       320       330

     630       640       650       660       670       680         
pF1KA0 LAKKSLDISVWDYDIGKSNDYIGGCQLGISAKGERLKHWYECLKNKDKKIERWHQLQNEN
       :: :.:...:::::::::::.::: .:: .:.::  ::: .::.. :  .:::: : .: 
XP_016 LATKTLEVTVWDYDIGKSNDFIGGVSLGPGARGEARKHWSDCLQQPDAALERWHTLTSEL
              340       350       360       370       380       390

     690         
pF1KA0 HVSSD     
                 
XP_016 PPAAGALSSA
              400

>>XP_016879266 (OMIM: 604567) PREDICTED: double C2-like   (400 aa)
 initn: 1398 init1: 708 opt: 1402  Z-score: 598.9  bits: 120.5 E(85289): 1.3e-26
Smith-Waterman score: 1407; 56.6% identity (75.6% similar) in 389 aa overlap (304-688:23-389)

           280       290       300       310       320       330   
pF1KA0 QASRPAPGSVQSPAPPQPGQPGTPGGSRPGPGPAGRFPDQKPEVAPSDPGTTAPPREERT
                                     :::  :   :  .  :  ::   :   :  
XP_016         MRGRRGDRMTINIQEHMAINVCPGPI-RPIRQISDYFPRGPG---P---EGG
                       10        20         30        40           

           340       350       360       370       380       390   
pF1KA0 GGVGGYPAVGAREDRMSHPSGPYSQASAAAPQPAAARQPPPPEEEEEEANSYDSDEATTL
       :: ::               .:   .  :   :::      ::.  : ..:::::.::.:
XP_016 GGGGG--------------EAPAHLVPLALAPPAALLGATTPEDGAE-VDSYDSDDATAL
          50                      60        70         80        90

           400       410       420       430       440       450   
pF1KA0 GALEFSLLYDQDNSSLQCTIIKAKGLKPMDSNGLADPYVKLHLLPGASKSNKLRTKTLRN
       :.:::.::::. . .:.:.:..:::::::: :::::::::::::::: :.:::.::: ::
XP_016 GTLEFDLLYDRASCTLHCSILRAKGLKPMDFNGLADPYVKLHLLPGACKANKLKTKTQRN
              100       110       120       130       140       150

           460       470       480       490       500       510   
pF1KA0 TRNPIWNETLVYHGITDEDMQRKTLRISVCDEDKFGHNEFIGETRFSLKKLKPNQRKNFN
       : ::.::: :.: ::::.:. .:.:::.::::::..::::::: :  :..:::.:.:.::
XP_016 TLNPVWNEDLTYSGITDDDITHKVLRIAVCDEDKLSHNEFIGEIRVPLRRLKPSQKKHFN
              160       170       180       190       200       210

           520       530          540        550       560         
pF1KA0 ICLERVIPMKRAGTTGSA-RGMALY--EEEQVER-VGDIEERGKILVSLMYSTQQGGLIV
       ::::: .:.   .. ..: ::.. :  : ::.:.  : .::::.::.:: ::... ::.:
XP_016 ICLERQVPLASPSSMSAALRGISCYLKELEQAEQGQGLLEERGRILLSLSYSSRRRGLLV
              220       230       240       250       260       270

     570       580       590       600       610       620         
pF1KA0 GIIRCVHLAAMDANGYSDPFVKLWLKPDMGKKAKHKTQIKKKTLNPEFNEEFFYDIKHSD
       ::.::.::::::.::::::.:: .:.::. ::.:::: .:::::::::::::::.:. : 
XP_016 GILRCAHLAAMDVNGYSDPYVKTYLRPDVDKKSKHKTCVKKKTLNPEFNEEFFYEIELST
              280       290       300       310       320       330

     630       640       650       660       670       680         
pF1KA0 LAKKSLDISVWDYDIGKSNDYIGGCQLGISAKGERLKHWYECLKNKDKKIERWHQLQNEN
       :: :.:...:::::::::::.::: .:: .:.::  ::: .::.. :  .:::: : .: 
XP_016 LATKTLEVTVWDYDIGKSNDFIGGVSLGPGARGEARKHWSDCLQQPDAALERWHTLTSEL
              340       350       360       370       380       390

     690         
pF1KA0 HVSSD     
                 
XP_016 PPAAGALSSA
              400

>>NP_001268997 (OMIM: 604567) double C2-like domain-cont  (400 aa)
 initn: 1398 init1: 708 opt: 1402  Z-score: 598.9  bits: 120.5 E(85289): 1.3e-26
Smith-Waterman score: 1407; 56.6% identity (75.6% similar) in 389 aa overlap (304-688:23-389)

           280       290       300       310       320       330   
pF1KA0 QASRPAPGSVQSPAPPQPGQPGTPGGSRPGPGPAGRFPDQKPEVAPSDPGTTAPPREERT
                                     :::  :   :  .  :  ::   :   :  
NP_001         MRGRRGDRMTINIQEHMAINVCPGPI-RPIRQISDYFPRGPG---P---EGG
                       10        20         30        40           

           340       350       360       370       380       390   
pF1KA0 GGVGGYPAVGAREDRMSHPSGPYSQASAAAPQPAAARQPPPPEEEEEEANSYDSDEATTL
       :: ::               .:   .  :   :::      ::.  : ..:::::.::.:
NP_001 GGGGG--------------EAPAHLVPLALAPPAALLGATTPEDGAE-VDSYDSDDATAL
          50                      60        70         80        90

           400       410       420       430       440       450   
pF1KA0 GALEFSLLYDQDNSSLQCTIIKAKGLKPMDSNGLADPYVKLHLLPGASKSNKLRTKTLRN
       :.:::.::::. . .:.:.:..:::::::: :::::::::::::::: :.:::.::: ::
NP_001 GTLEFDLLYDRASCTLHCSILRAKGLKPMDFNGLADPYVKLHLLPGACKANKLKTKTQRN
              100       110       120       130       140       150

           460       470       480       490       500       510   
pF1KA0 TRNPIWNETLVYHGITDEDMQRKTLRISVCDEDKFGHNEFIGETRFSLKKLKPNQRKNFN
       : ::.::: :.: ::::.:. .:.:::.::::::..::::::: :  :..:::.:.:.::
NP_001 TLNPVWNEDLTYSGITDDDITHKVLRIAVCDEDKLSHNEFIGEIRVPLRRLKPSQKKHFN
              160       170       180       190       200       210

           520       530          540        550       560         
pF1KA0 ICLERVIPMKRAGTTGSA-RGMALY--EEEQVER-VGDIEERGKILVSLMYSTQQGGLIV
       ::::: .:.   .. ..: ::.. :  : ::.:.  : .::::.::.:: ::... ::.:
NP_001 ICLERQVPLASPSSMSAALRGISCYLKELEQAEQGQGLLEERGRILLSLSYSSRRRGLLV
              220       230       240       250       260       270

     570       580       590       600       610       620         
pF1KA0 GIIRCVHLAAMDANGYSDPFVKLWLKPDMGKKAKHKTQIKKKTLNPEFNEEFFYDIKHSD
       ::.::.::::::.::::::.:: .:.::. ::.:::: .:::::::::::::::.:. : 
NP_001 GILRCAHLAAMDVNGYSDPYVKTYLRPDVDKKSKHKTCVKKKTLNPEFNEEFFYEIELST
              280       290       300       310       320       330

     630       640       650       660       670       680         
pF1KA0 LAKKSLDISVWDYDIGKSNDYIGGCQLGISAKGERLKHWYECLKNKDKKIERWHQLQNEN
       :: :.:...:::::::::::.::: .:: .:.::  ::: .::.. :  .:::: : .: 
NP_001 LATKTLEVTVWDYDIGKSNDFIGGVSLGPGARGEARKHWSDCLQQPDAALERWHTLTSEL
              340       350       360       370       380       390

     690         
pF1KA0 HVSSD     
                 
NP_001 PPAAGALSSA
              400

>>NP_003577 (OMIM: 604567) double C2-like domain-contain  (400 aa)
 initn: 1398 init1: 708 opt: 1402  Z-score: 598.9  bits: 120.5 E(85289): 1.3e-26
Smith-Waterman score: 1407; 56.6% identity (75.6% similar) in 389 aa overlap (304-688:23-389)

           280       290       300       310       320       330   
pF1KA0 QASRPAPGSVQSPAPPQPGQPGTPGGSRPGPGPAGRFPDQKPEVAPSDPGTTAPPREERT
                                     :::  :   :  .  :  ::   :   :  
NP_003         MRGRRGDRMTINIQEHMAINVCPGPI-RPIRQISDYFPRGPG---P---EGG
                       10        20         30        40           

           340       350       360       370       380       390   
pF1KA0 GGVGGYPAVGAREDRMSHPSGPYSQASAAAPQPAAARQPPPPEEEEEEANSYDSDEATTL
       :: ::               .:   .  :   :::      ::.  : ..:::::.::.:
NP_003 GGGGG--------------EAPAHLVPLALAPPAALLGATTPEDGAE-VDSYDSDDATAL
          50                      60        70         80        90

           400       410       420       430       440       450   
pF1KA0 GALEFSLLYDQDNSSLQCTIIKAKGLKPMDSNGLADPYVKLHLLPGASKSNKLRTKTLRN
       :.:::.::::. . .:.:.:..:::::::: :::::::::::::::: :.:::.::: ::
NP_003 GTLEFDLLYDRASCTLHCSILRAKGLKPMDFNGLADPYVKLHLLPGACKANKLKTKTQRN
              100       110       120       130       140       150

           460       470       480       490       500       510   
pF1KA0 TRNPIWNETLVYHGITDEDMQRKTLRISVCDEDKFGHNEFIGETRFSLKKLKPNQRKNFN
       : ::.::: :.: ::::.:. .:.:::.::::::..::::::: :  :..:::.:.:.::
NP_003 TLNPVWNEDLTYSGITDDDITHKVLRIAVCDEDKLSHNEFIGEIRVPLRRLKPSQKKHFN
              160       170       180       190       200       210

           520       530          540        550       560         
pF1KA0 ICLERVIPMKRAGTTGSA-RGMALY--EEEQVER-VGDIEERGKILVSLMYSTQQGGLIV
       ::::: .:.   .. ..: ::.. :  : ::.:.  : .::::.::.:: ::... ::.:
NP_003 ICLERQVPLASPSSMSAALRGISCYLKELEQAEQGQGLLEERGRILLSLSYSSRRRGLLV
              220       230       240       250       260       270

     570       580       590       600       610       620         
pF1KA0 GIIRCVHLAAMDANGYSDPFVKLWLKPDMGKKAKHKTQIKKKTLNPEFNEEFFYDIKHSD
       ::.::.::::::.::::::.:: .:.::. ::.:::: .:::::::::::::::.:. : 
NP_003 GILRCAHLAAMDVNGYSDPYVKTYLRPDVDKKSKHKTCVKKKTLNPEFNEEFFYEIELST
              280       290       300       310       320       330

     630       640       650       660       670       680         
pF1KA0 LAKKSLDISVWDYDIGKSNDYIGGCQLGISAKGERLKHWYECLKNKDKKIERWHQLQNEN
       :: :.:...:::::::::::.::: .:: .:.::  ::: .::.. :  .:::: : .: 
NP_003 LATKTLEVTVWDYDIGKSNDFIGGVSLGPGARGEARKHWSDCLQQPDAALERWHTLTSEL
              340       350       360       370       380       390

     690         
pF1KA0 HVSSD     
                 
NP_003 PPAAGALSSA
              400

>>NP_001268992 (OMIM: 604567) double C2-like domain-cont  (400 aa)
 initn: 1398 init1: 708 opt: 1402  Z-score: 598.9  bits: 120.5 E(85289): 1.3e-26
Smith-Waterman score: 1407; 56.6% identity (75.6% similar) in 389 aa overlap (304-688:23-389)

           280       290       300       310       320       330   
pF1KA0 QASRPAPGSVQSPAPPQPGQPGTPGGSRPGPGPAGRFPDQKPEVAPSDPGTTAPPREERT
                                     :::  :   :  .  :  ::   :   :  
NP_001         MRGRRGDRMTINIQEHMAINVCPGPI-RPIRQISDYFPRGPG---P---EGG
                       10        20         30        40           

           340       350       360       370       380       390   
pF1KA0 GGVGGYPAVGAREDRMSHPSGPYSQASAAAPQPAAARQPPPPEEEEEEANSYDSDEATTL
       :: ::               .:   .  :   :::      ::.  : ..:::::.::.:
NP_001 GGGGG--------------EAPAHLVPLALAPPAALLGATTPEDGAE-VDSYDSDDATAL
          50                      60        70         80        90

           400       410       420       430       440       450   
pF1KA0 GALEFSLLYDQDNSSLQCTIIKAKGLKPMDSNGLADPYVKLHLLPGASKSNKLRTKTLRN
       :.:::.::::. . .:.:.:..:::::::: :::::::::::::::: :.:::.::: ::
NP_001 GTLEFDLLYDRASCTLHCSILRAKGLKPMDFNGLADPYVKLHLLPGACKANKLKTKTQRN
              100       110       120       130       140       150

           460       470       480       490       500       510   
pF1KA0 TRNPIWNETLVYHGITDEDMQRKTLRISVCDEDKFGHNEFIGETRFSLKKLKPNQRKNFN
       : ::.::: :.: ::::.:. .:.:::.::::::..::::::: :  :..:::.:.:.::
NP_001 TLNPVWNEDLTYSGITDDDITHKVLRIAVCDEDKLSHNEFIGEIRVPLRRLKPSQKKHFN
              160       170       180       190       200       210

           520       530          540        550       560         
pF1KA0 ICLERVIPMKRAGTTGSA-RGMALY--EEEQVER-VGDIEERGKILVSLMYSTQQGGLIV
       ::::: .:.   .. ..: ::.. :  : ::.:.  : .::::.::.:: ::... ::.:
NP_001 ICLERQVPLASPSSMSAALRGISCYLKELEQAEQGQGLLEERGRILLSLSYSSRRRGLLV
              220       230       240       250       260       270

     570       580       590       600       610       620         
pF1KA0 GIIRCVHLAAMDANGYSDPFVKLWLKPDMGKKAKHKTQIKKKTLNPEFNEEFFYDIKHSD
       ::.::.::::::.::::::.:: .:.::. ::.:::: .:::::::::::::::.:. : 
NP_001 GILRCAHLAAMDVNGYSDPYVKTYLRPDVDKKSKHKTCVKKKTLNPEFNEEFFYEIELST
              280       290       300       310       320       330

     630       640       650       660       670       680         
pF1KA0 LAKKSLDISVWDYDIGKSNDYIGGCQLGISAKGERLKHWYECLKNKDKKIERWHQLQNEN
       :: :.:...:::::::::::.::: .:: .:.::  ::: .::.. :  .:::: : .: 
NP_001 LATKTLEVTVWDYDIGKSNDFIGGVSLGPGARGEARKHWSDCLQQPDAALERWHTLTSEL
              340       350       360       370       380       390

     690         
pF1KA0 HVSSD     
                 
NP_001 PPAAGALSSA
              400

>>NP_001268991 (OMIM: 604567) double C2-like domain-cont  (400 aa)
 initn: 1398 init1: 708 opt: 1402  Z-score: 598.9  bits: 120.5 E(85289): 1.3e-26
Smith-Waterman score: 1407; 56.6% identity (75.6% similar) in 389 aa overlap (304-688:23-389)

           280       290       300       310       320       330   
pF1KA0 QASRPAPGSVQSPAPPQPGQPGTPGGSRPGPGPAGRFPDQKPEVAPSDPGTTAPPREERT
                                     :::  :   :  .  :  ::   :   :  
NP_001         MRGRRGDRMTINIQEHMAINVCPGPI-RPIRQISDYFPRGPG---P---EGG
                       10        20         30        40           

           340       350       360       370       380       390   
pF1KA0 GGVGGYPAVGAREDRMSHPSGPYSQASAAAPQPAAARQPPPPEEEEEEANSYDSDEATTL
       :: ::               .:   .  :   :::      ::.  : ..:::::.::.:
NP_001 GGGGG--------------EAPAHLVPLALAPPAALLGATTPEDGAE-VDSYDSDDATAL
          50                      60        70         80        90

           400       410       420       430       440       450   
pF1KA0 GALEFSLLYDQDNSSLQCTIIKAKGLKPMDSNGLADPYVKLHLLPGASKSNKLRTKTLRN
       :.:::.::::. . .:.:.:..:::::::: :::::::::::::::: :.:::.::: ::
NP_001 GTLEFDLLYDRASCTLHCSILRAKGLKPMDFNGLADPYVKLHLLPGACKANKLKTKTQRN
              100       110       120       130       140       150

           460       470       480       490       500       510   
pF1KA0 TRNPIWNETLVYHGITDEDMQRKTLRISVCDEDKFGHNEFIGETRFSLKKLKPNQRKNFN
       : ::.::: :.: ::::.:. .:.:::.::::::..::::::: :  :..:::.:.:.::
NP_001 TLNPVWNEDLTYSGITDDDITHKVLRIAVCDEDKLSHNEFIGEIRVPLRRLKPSQKKHFN
              160       170       180       190       200       210

           520       530          540        550       560         
pF1KA0 ICLERVIPMKRAGTTGSA-RGMALY--EEEQVER-VGDIEERGKILVSLMYSTQQGGLIV
       ::::: .:.   .. ..: ::.. :  : ::.:.  : .::::.::.:: ::... ::.:
NP_001 ICLERQVPLASPSSMSAALRGISCYLKELEQAEQGQGLLEERGRILLSLSYSSRRRGLLV
              220       230       240       250       260       270

     570       580       590       600       610       620         
pF1KA0 GIIRCVHLAAMDANGYSDPFVKLWLKPDMGKKAKHKTQIKKKTLNPEFNEEFFYDIKHSD
       ::.::.::::::.::::::.:: .:.::. ::.:::: .:::::::::::::::.:. : 
NP_001 GILRCAHLAAMDVNGYSDPYVKTYLRPDVDKKSKHKTCVKKKTLNPEFNEEFFYEIELST
              280       290       300       310       320       330

     630       640       650       660       670       680         
pF1KA0 LAKKSLDISVWDYDIGKSNDYIGGCQLGISAKGERLKHWYECLKNKDKKIERWHQLQNEN
       :: :.:...:::::::::::.::: .:: .:.::  ::: .::.. :  .:::: : .: 
NP_001 LATKTLEVTVWDYDIGKSNDFIGGVSLGPGARGEARKHWSDCLQQPDAALERWHTLTSEL
              340       350       360       370       380       390

     690         
pF1KA0 HVSSD     
                 
NP_001 PPAAGALSSA
              400




694 residues in 1 query   sequences
60827320 residues in 85289 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Wed Nov  2 20:11:59 2016 done: Wed Nov  2 20:12:00 2016
 Total Scan time: 12.060 Total Display time:  0.100

Function used was FASTA [36.3.4 Apr, 2011]
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