Result of FASTA (omim) for pF1KA0358
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KA0358, 1581 aa
  1>>>pF1KA0358 1581 - 1581 aa - 1581 aa
Library: /omim/omim.rfq.tfa
  60827320 residues in 85289 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 8.0708+/-0.000418; mu= 10.4035+/- 0.026
 mean_var=133.3839+/-28.363, 0's: 0 Z-trim(115.9): 161  B-trim: 1309 in 2/54
 Lambda= 0.111051
 statistics sampled from 26460 (26632) to 26460 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.657), E-opt: 0.2 (0.312), width:  16
 Scan time: 13.330

The best scores are:                                      opt bits E(85289)
NP_569831 (OMIM: 603584) MAP kinase-activating dea (1581) 10463 1688.9       0
XP_005253257 (OMIM: 603584) PREDICTED: MAP kinase- (1580) 10446 1686.2       0
XP_016873977 (OMIM: 603584) PREDICTED: MAP kinase- (1577) 10425 1682.8       0
XP_016873978 (OMIM: 603584) PREDICTED: MAP kinase- (1577) 10425 1682.8       0
NP_003673 (OMIM: 603584) MAP kinase-activating dea (1647) 10416 1681.4       0
XP_005253246 (OMIM: 603584) PREDICTED: MAP kinase- (1647) 10416 1681.4       0
XP_016873967 (OMIM: 603584) PREDICTED: MAP kinase- (1643) 10378 1675.3       0
XP_016873979 (OMIM: 603584) PREDICTED: MAP kinase- (1563) 7477 1210.5       0
XP_016873980 (OMIM: 603584) PREDICTED: MAP kinase- (1562) 7475 1210.2       0
XP_016873981 (OMIM: 603584) PREDICTED: MAP kinase- (1559) 7472 1209.7       0
XP_016873968 (OMIM: 603584) PREDICTED: MAP kinase- (1625) 7472 1209.7       0
XP_005253253 (OMIM: 603584) PREDICTED: MAP kinase- (1608) 7447 1205.7       0
NP_569829 (OMIM: 603584) MAP kinase-activating dea (1608) 7447 1205.7       0
XP_016873969 (OMIM: 603584) PREDICTED: MAP kinase- (1607) 7442 1204.9       0
XP_016873971 (OMIM: 603584) PREDICTED: MAP kinase- (1604) 7439 1204.4       0
XP_016873989 (OMIM: 603584) PREDICTED: MAP kinase- (1521) 5885 955.4       0
XP_016873986 (OMIM: 603584) PREDICTED: MAP kinase- (1539) 5885 955.4       0
XP_016873985 (OMIM: 603584) PREDICTED: MAP kinase- (1539) 5885 955.4       0
XP_016873984 (OMIM: 603584) PREDICTED: MAP kinase- (1542) 5885 955.4       0
XP_016873983 (OMIM: 603584) PREDICTED: MAP kinase- (1543) 5885 955.4       0
XP_016873982 (OMIM: 603584) PREDICTED: MAP kinase- (1557) 5885 955.4       0
XP_016873974 (OMIM: 603584) PREDICTED: MAP kinase- (1584) 5885 955.4       0
XP_016873973 (OMIM: 603584) PREDICTED: MAP kinase- (1584) 5885 955.4       0
NP_569832 (OMIM: 603584) MAP kinase-activating dea (1587) 5885 955.4       0
NP_569826 (OMIM: 603584) MAP kinase-activating dea (1588) 5885 955.4       0
XP_005253256 (OMIM: 603584) PREDICTED: MAP kinase- (1588) 5885 955.4       0
XP_016873970 (OMIM: 603584) PREDICTED: MAP kinase- (1605) 5885 955.4       0
XP_005253262 (OMIM: 603584) PREDICTED: MAP kinase- (1479) 5079 826.3       0
NP_569830 (OMIM: 603584) MAP kinase-activating dea (1479) 5079 826.3       0
XP_016873999 (OMIM: 603584) PREDICTED: MAP kinase- (1496) 5079 826.3       0
XP_016873998 (OMIM: 603584) PREDICTED: MAP kinase- (1499) 5079 826.3       0
XP_016873997 (OMIM: 603584) PREDICTED: MAP kinase- (1500) 5079 826.3       0
XP_016873996 (OMIM: 603584) PREDICTED: MAP kinase- (1514) 5079 826.3       0
XP_016873995 (OMIM: 603584) PREDICTED: MAP kinase- (1516) 5079 826.3       0
XP_016873994 (OMIM: 603584) PREDICTED: MAP kinase- (1516) 5079 826.3       0
XP_016873993 (OMIM: 603584) PREDICTED: MAP kinase- (1519) 5079 826.3       0
XP_016873992 (OMIM: 603584) PREDICTED: MAP kinase- (1519) 5079 826.3       0
XP_016873990 (OMIM: 603584) PREDICTED: MAP kinase- (1520) 5079 826.3       0
XP_016873991 (OMIM: 603584) PREDICTED: MAP kinase- (1520) 5079 826.3       0
XP_016873988 (OMIM: 603584) PREDICTED: MAP kinase- (1534) 5079 826.3       0
XP_016873987 (OMIM: 603584) PREDICTED: MAP kinase- (1534) 5079 826.3       0
NP_001129416 (OMIM: 603584) MAP kinase-activating  (1541) 5079 826.3       0
XP_005253261 (OMIM: 603584) PREDICTED: MAP kinase- (1541) 5079 826.3       0
NP_001129415 (OMIM: 603584) MAP kinase-activating  (1544) 5079 826.3       0
XP_005253260 (OMIM: 603584) PREDICTED: MAP kinase- (1545) 5079 826.3       0
NP_569828 (OMIM: 603584) MAP kinase-activating dea (1545) 5079 826.3       0
XP_005253258 (OMIM: 603584) PREDICTED: MAP kinase- (1565) 5079 826.3       0
NP_569827 (OMIM: 603584) MAP kinase-activating dea (1565) 5079 826.3       0
XP_016873976 (OMIM: 603584) PREDICTED: MAP kinase- (1580) 5079 826.3       0
XP_016873975 (OMIM: 603584) PREDICTED: MAP kinase- (1582) 5079 826.3       0


>>NP_569831 (OMIM: 603584) MAP kinase-activating death d  (1581 aa)
 initn: 10463 init1: 10463 opt: 10463  Z-score: 9058.1  bits: 1688.9 E(85289):    0
Smith-Waterman score: 10463; 100.0% identity (100.0% similar) in 1581 aa overlap (1-1581:1-1581)

               10        20        30        40        50        60
pF1KA0 MVQKKKFCPRLLDYLVIVGARHPSSDSVAQTPELLRRYPLEDHTEFPLPPDVVFFCQPEG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_569 MVQKKKFCPRLLDYLVIVGARHPSSDSVAQTPELLRRYPLEDHTEFPLPPDVVFFCQPEG
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KA0 CLSVRQRRMSLRDDTSFVFTLTDKDTGVTRYGICVNFYRSFQKRISKEKGEGGAGSRGKE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_569 CLSVRQRRMSLRDDTSFVFTLTDKDTGVTRYGICVNFYRSFQKRISKEKGEGGAGSRGKE
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KA0 GTHATCASEEGGTESSESGSSLQPLSADSTPDVNQSPRGKRRAKAGSRSRNSTLTSLCVL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_569 GTHATCASEEGGTESSESGSSLQPLSADSTPDVNQSPRGKRRAKAGSRSRNSTLTSLCVL
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KA0 SHYPFFSTFRECLYTLKRLVDCCSERLLGKKLGIPRGVQRDTMWRIFTGSLLVEEKSSAL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_569 SHYPFFSTFRECLYTLKRLVDCCSERLLGKKLGIPRGVQRDTMWRIFTGSLLVEEKSSAL
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KA0 LHDLREIEAWIYRLLRSPVPVSGQKRVDIEVLPQELQPALTFALPDPSRFTLVDFPLHLP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_569 LHDLREIEAWIYRLLRSPVPVSGQKRVDIEVLPQELQPALTFALPDPSRFTLVDFPLHLP
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KA0 LELLGVDACLQVLTCILLEHKVVLQSRDYNALSMSVMAFVAMIYPLEYMFPVIPLLPTCM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_569 LELLGVDACLQVLTCILLEHKVVLQSRDYNALSMSVMAFVAMIYPLEYMFPVIPLLPTCM
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KA0 ASAEQLLLAPTPYIIGVPASFFLYKLDFKMPDDVWLVDLDSNRVIAPTNAEVLPILPEPE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_569 ASAEQLLLAPTPYIIGVPASFFLYKLDFKMPDDVWLVDLDSNRVIAPTNAEVLPILPEPE
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KA0 SLELKKHLKQALASMSLNTQPILNLEKFHEGQEIPLLLGRPSNDLQSTPSTEFNPLIYGN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_569 SLELKKHLKQALASMSLNTQPILNLEKFHEGQEIPLLLGRPSNDLQSTPSTEFNPLIYGN
              430       440       450       460       470       480

              490       500       510       520       530       540
pF1KA0 DVDSVDVATRVAMVRFFNSANVLQGFQMHTRTLRLFPRPVVAFQAGSFLASRPRQTPFAE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_569 DVDSVDVATRVAMVRFFNSANVLQGFQMHTRTLRLFPRPVVAFQAGSFLASRPRQTPFAE
              490       500       510       520       530       540

              550       560       570       580       590       600
pF1KA0 KLARTQAVEYFGEWILNPTNYAFQRIHNNMFDPALIGDKPKWYAHQLQPIHYRVYDSNSQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_569 KLARTQAVEYFGEWILNPTNYAFQRIHNNMFDPALIGDKPKWYAHQLQPIHYRVYDSNSQ
              550       560       570       580       590       600

              610       620       630       640       650       660
pF1KA0 LAEALSVPPERDSDSEPTDDSGSDSMDYDDSSSSYSSLGDFVSEMMKCDINGDTPNVDPL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_569 LAEALSVPPERDSDSEPTDDSGSDSMDYDDSSSSYSSLGDFVSEMMKCDINGDTPNVDPL
              610       620       630       640       650       660

              670       680       690       700       710       720
pF1KA0 THAALGDASEVEIDELQNQKEAEEPGPDSENSQENPPLRSSSSTTASSSPSTVIHGANSE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_569 THAALGDASEVEIDELQNQKEAEEPGPDSENSQENPPLRSSSSTTASSSPSTVIHGANSE
              670       680       690       700       710       720

              730       740       750       760       770       780
pF1KA0 PADSTEMDDKAAVGVSKPLPSVPPSIGKSNVDRRQAEIGEGSVRRRIYDNPYFEPQYGFP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_569 PADSTEMDDKAAVGVSKPLPSVPPSIGKSNVDRRQAEIGEGSVRRRIYDNPYFEPQYGFP
              730       740       750       760       770       780

              790       800       810       820       830       840
pF1KA0 PEEDEDEQGESYTPRFSQHVSGNRAQKLLRPNSLRLASDSDAESDSRASSPNSTVSNTST
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_569 PEEDEDEQGESYTPRFSQHVSGNRAQKLLRPNSLRLASDSDAESDSRASSPNSTVSNTST
              790       800       810       820       830       840

              850       860       870       880       890       900
pF1KA0 EGFGGIMSFASSLYRNHSTSFSLSNLTLPTKGAREKATPFPSLKVFGLNTLMEIVTEAGP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_569 EGFGGIMSFASSLYRNHSTSFSLSNLTLPTKGAREKATPFPSLKVFGLNTLMEIVTEAGP
              850       860       870       880       890       900

              910       920       930       940       950       960
pF1KA0 GSGEGNRRALVDQKSSVIKHSPTVKREPPSPQGRSSNSSENQQFLKEVVHSVLDGQGVGW
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_569 GSGEGNRRALVDQKSSVIKHSPTVKREPPSPQGRSSNSSENQQFLKEVVHSVLDGQGVGW
              910       920       930       940       950       960

              970       980       990      1000      1010      1020
pF1KA0 LNMKKVRRLLESEQLRVFVLSKLNRMVQSEDDARQDIIPDVEISRKVYKGMLDLLKCTVL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_569 LNMKKVRRLLESEQLRVFVLSKLNRMVQSEDDARQDIIPDVEISRKVYKGMLDLLKCTVL
              970       980       990      1000      1010      1020

             1030      1040      1050      1060      1070      1080
pF1KA0 SLEQSYAHAGLGGMASIFGLLEIAQTHYYSKEPDKRKRSPTESVNTPVGKDPGLAGRGDP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_569 SLEQSYAHAGLGGMASIFGLLEIAQTHYYSKEPDKRKRSPTESVNTPVGKDPGLAGRGDP
             1030      1040      1050      1060      1070      1080

             1090      1100      1110      1120      1130      1140
pF1KA0 KAMAQLRVPQLGPRAPSATGKGPKELDTRSLKEENFIASIELWNKHQEVKKQKALEKQRP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_569 KAMAQLRVPQLGPRAPSATGKGPKELDTRSLKEENFIASIELWNKHQEVKKQKALEKQRP
             1090      1100      1110      1120      1130      1140

             1150      1160      1170      1180      1190      1200
pF1KA0 EVIKPVFDLGETEEKKSQISADSGVSLTSSSQRTDQDSVIGVSPAVMIRSSSQDSEVSTV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_569 EVIKPVFDLGETEEKKSQISADSGVSLTSSSQRTDQDSVIGVSPAVMIRSSSQDSEVSTV
             1150      1160      1170      1180      1190      1200

             1210      1220      1230      1240      1250      1260
pF1KA0 VSNSSGETLGADSDLSSNAGDGPGGEGSVHLASSRGTLSDSEIETNSATSTIFGKAHSLK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_569 VSNSSGETLGADSDLSSNAGDGPGGEGSVHLASSRGTLSDSEIETNSATSTIFGKAHSLK
             1210      1220      1230      1240      1250      1260

             1270      1280      1290      1300      1310      1320
pF1KA0 PSIKEKLAGSPIRTSEDVSQRVYLYEGLLGRDKGSMWDQLEDAAMETFSISKERSTLWDQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_569 PSIKEKLAGSPIRTSEDVSQRVYLYEGLLGRDKGSMWDQLEDAAMETFSISKERSTLWDQ
             1270      1280      1290      1300      1310      1320

             1330      1340      1350      1360      1370      1380
pF1KA0 MQFWEDAFLDAVMLEREGMGMDQGPQEMIDRYLSLGEHDRKRLEDDEDRLLATLLHNLIS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_569 MQFWEDAFLDAVMLEREGMGMDQGPQEMIDRYLSLGEHDRKRLEDDEDRLLATLLHNLIS
             1330      1340      1350      1360      1370      1380

             1390      1400      1410      1420      1430      1440
pF1KA0 YMLLMKVNKNDIRKKVRRLMGKSHIGLVYSQQINEVLDQLANLNGRDLSIWSSGSRHMKK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_569 YMLLMKVNKNDIRKKVRRLMGKSHIGLVYSQQINEVLDQLANLNGRDLSIWSSGSRHMKK
             1390      1400      1410      1420      1430      1440

             1450      1460      1470      1480      1490      1500
pF1KA0 QTFVVHAGTDTNGDIFFMEVCDDCVVLRSNIGTVYERWWYEKLINMTYCPKTKVLCLWRR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_569 QTFVVHAGTDTNGDIFFMEVCDDCVVLRSNIGTVYERWWYEKLINMTYCPKTKVLCLWRR
             1450      1460      1470      1480      1490      1500

             1510      1520      1530      1540      1550      1560
pF1KA0 NGSETQLNKFYTKKCRELYYCVKDSMERAAARQQSIKPGPELGGEFPVQDLKTGEGGLLQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_569 NGSETQLNKFYTKKCRELYYCVKDSMERAAARQQSIKPGPELGGEFPVQDLKTGEGGLLQ
             1510      1520      1530      1540      1550      1560

             1570      1580 
pF1KA0 VTLEGINLKFMHNQFLKLKKW
       :::::::::::::::::::::
NP_569 VTLEGINLKFMHNQFLKLKKW
             1570      1580 

>>XP_005253257 (OMIM: 603584) PREDICTED: MAP kinase-acti  (1580 aa)
 initn: 7922 init1: 7922 opt: 10446  Z-score: 9043.4  bits: 1686.2 E(85289):    0
Smith-Waterman score: 10446; 99.9% identity (99.9% similar) in 1581 aa overlap (1-1581:1-1580)

               10        20        30        40        50        60
pF1KA0 MVQKKKFCPRLLDYLVIVGARHPSSDSVAQTPELLRRYPLEDHTEFPLPPDVVFFCQPEG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MVQKKKFCPRLLDYLVIVGARHPSSDSVAQTPELLRRYPLEDHTEFPLPPDVVFFCQPEG
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KA0 CLSVRQRRMSLRDDTSFVFTLTDKDTGVTRYGICVNFYRSFQKRISKEKGEGGAGSRGKE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 CLSVRQRRMSLRDDTSFVFTLTDKDTGVTRYGICVNFYRSFQKRISKEKGEGGAGSRGKE
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KA0 GTHATCASEEGGTESSESGSSLQPLSADSTPDVNQSPRGKRRAKAGSRSRNSTLTSLCVL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 GTHATCASEEGGTESSESGSSLQPLSADSTPDVNQSPRGKRRAKAGSRSRNSTLTSLCVL
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KA0 SHYPFFSTFRECLYTLKRLVDCCSERLLGKKLGIPRGVQRDTMWRIFTGSLLVEEKSSAL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SHYPFFSTFRECLYTLKRLVDCCSERLLGKKLGIPRGVQRDTMWRIFTGSLLVEEKSSAL
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KA0 LHDLREIEAWIYRLLRSPVPVSGQKRVDIEVLPQELQPALTFALPDPSRFTLVDFPLHLP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LHDLREIEAWIYRLLRSPVPVSGQKRVDIEVLPQELQPALTFALPDPSRFTLVDFPLHLP
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KA0 LELLGVDACLQVLTCILLEHKVVLQSRDYNALSMSVMAFVAMIYPLEYMFPVIPLLPTCM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LELLGVDACLQVLTCILLEHKVVLQSRDYNALSMSVMAFVAMIYPLEYMFPVIPLLPTCM
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KA0 ASAEQLLLAPTPYIIGVPASFFLYKLDFKMPDDVWLVDLDSNRVIAPTNAEVLPILPEPE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 ASAEQLLLAPTPYIIGVPASFFLYKLDFKMPDDVWLVDLDSNRVIAPTNAEVLPILPEPE
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KA0 SLELKKHLKQALASMSLNTQPILNLEKFHEGQEIPLLLGRPSNDLQSTPSTEFNPLIYGN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SLELKKHLKQALASMSLNTQPILNLEKFHEGQEIPLLLGRPSNDLQSTPSTEFNPLIYGN
              430       440       450       460       470       480

              490       500       510       520       530       540
pF1KA0 DVDSVDVATRVAMVRFFNSANVLQGFQMHTRTLRLFPRPVVAFQAGSFLASRPRQTPFAE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 DVDSVDVATRVAMVRFFNSANVLQGFQMHTRTLRLFPRPVVAFQAGSFLASRPRQTPFAE
              490       500       510       520       530       540

              550       560       570       580       590       600
pF1KA0 KLARTQAVEYFGEWILNPTNYAFQRIHNNMFDPALIGDKPKWYAHQLQPIHYRVYDSNSQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 KLARTQAVEYFGEWILNPTNYAFQRIHNNMFDPALIGDKPKWYAHQLQPIHYRVYDSNSQ
              550       560       570       580       590       600

              610       620       630       640       650       660
pF1KA0 LAEALSVPPERDSDSEPTDDSGSDSMDYDDSSSSYSSLGDFVSEMMKCDINGDTPNVDPL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LAEALSVPPERDSDSEPTDDSGSDSMDYDDSSSSYSSLGDFVSEMMKCDINGDTPNVDPL
              610       620       630       640       650       660

              670       680       690       700       710       720
pF1KA0 THAALGDASEVEIDELQNQKEAEEPGPDSENSQENPPLRSSSSTTASSSPSTVIHGANSE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 THAALGDASEVEIDELQNQKEAEEPGPDSENSQENPPLRSSSSTTASSSPSTVIHGANSE
              670       680       690       700       710       720

              730       740       750       760       770       780
pF1KA0 PADSTEMDDKAAVGVSKPLPSVPPSIGKSNVDRRQAEIGEGSVRRRIYDNPYFEPQYGFP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 PADSTEMDDKAAVGVSKPLPSVPPSIGKSNVDRRQAEIGEGSVRRRIYDNPYFEPQYGFP
              730       740       750       760       770       780

              790       800       810       820       830       840
pF1KA0 PEEDEDEQGESYTPRFSQHVSGNRAQKLLRPNSLRLASDSDAESDSRASSPNSTVSNTST
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 PEEDEDEQGESYTPRFSQHVSGNRAQKLLRPNSLRLASDSDAESDSRASSPNSTVSNTST
              790       800       810       820       830       840

              850       860       870       880       890       900
pF1KA0 EGFGGIMSFASSLYRNHSTSFSLSNLTLPTKGAREKATPFPSLKVFGLNTLMEIVTEAGP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 EGFGGIMSFASSLYRNHSTSFSLSNLTLPTKGAREKATPFPSLKVFGLNTLMEIVTEAGP
              850       860       870       880       890       900

              910       920       930       940       950       960
pF1KA0 GSGEGNRRALVDQKSSVIKHSPTVKREPPSPQGRSSNSSENQQFLKEVVHSVLDGQGVGW
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 GSGEGNRRALVDQKSSVIKHSPTVKREPPSPQGRSSNSSENQQFLKEVVHSVLDGQGVGW
              910       920       930       940       950       960

              970       980       990      1000      1010      1020
pF1KA0 LNMKKVRRLLESEQLRVFVLSKLNRMVQSEDDARQDIIPDVEISRKVYKGMLDLLKCTVL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LNMKKVRRLLESEQLRVFVLSKLNRMVQSEDDARQDIIPDVEISRKVYKGMLDLLKCTVL
              970       980       990      1000      1010      1020

             1030      1040      1050      1060      1070      1080
pF1KA0 SLEQSYAHAGLGGMASIFGLLEIAQTHYYSKEPDKRKRSPTESVNTPVGKDPGLAGRGDP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SLEQSYAHAGLGGMASIFGLLEIAQTHYYSKEPDKRKRSPTESVNTPVGKDPGLAGRGDP
             1030      1040      1050      1060      1070      1080

             1090      1100      1110      1120      1130      1140
pF1KA0 KAMAQLRVPQLGPRAPSATGKGPKELDTRSLKEENFIASIELWNKHQEVKKQKALEKQRP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 KAMAQLRVPQLGPRAPSATGKGPKELDTRSLKEENFIASIELWNKHQEVKKQKALEKQRP
             1090      1100      1110      1120      1130      1140

             1150      1160      1170      1180      1190      1200
pF1KA0 EVIKPVFDLGETEEKKSQISADSGVSLTSSSQRTDQDSVIGVSPAVMIRSSSQDSEVSTV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 EVIKPVFDLGETEEKKSQISADSGVSLTSSSQRTDQDSVIGVSPAVMIRSSSQDSEVSTV
             1150      1160      1170      1180      1190      1200

             1210      1220      1230      1240      1250      1260
pF1KA0 VSNSSGETLGADSDLSSNAGDGPGGEGSVHLASSRGTLSDSEIETNSATSTIFGKAHSLK
        :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 -SNSSGETLGADSDLSSNAGDGPGGEGSVHLASSRGTLSDSEIETNSATSTIFGKAHSLK
              1210      1220      1230      1240      1250         

             1270      1280      1290      1300      1310      1320
pF1KA0 PSIKEKLAGSPIRTSEDVSQRVYLYEGLLGRDKGSMWDQLEDAAMETFSISKERSTLWDQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 PSIKEKLAGSPIRTSEDVSQRVYLYEGLLGRDKGSMWDQLEDAAMETFSISKERSTLWDQ
    1260      1270      1280      1290      1300      1310         

             1330      1340      1350      1360      1370      1380
pF1KA0 MQFWEDAFLDAVMLEREGMGMDQGPQEMIDRYLSLGEHDRKRLEDDEDRLLATLLHNLIS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MQFWEDAFLDAVMLEREGMGMDQGPQEMIDRYLSLGEHDRKRLEDDEDRLLATLLHNLIS
    1320      1330      1340      1350      1360      1370         

             1390      1400      1410      1420      1430      1440
pF1KA0 YMLLMKVNKNDIRKKVRRLMGKSHIGLVYSQQINEVLDQLANLNGRDLSIWSSGSRHMKK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 YMLLMKVNKNDIRKKVRRLMGKSHIGLVYSQQINEVLDQLANLNGRDLSIWSSGSRHMKK
    1380      1390      1400      1410      1420      1430         

             1450      1460      1470      1480      1490      1500
pF1KA0 QTFVVHAGTDTNGDIFFMEVCDDCVVLRSNIGTVYERWWYEKLINMTYCPKTKVLCLWRR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 QTFVVHAGTDTNGDIFFMEVCDDCVVLRSNIGTVYERWWYEKLINMTYCPKTKVLCLWRR
    1440      1450      1460      1470      1480      1490         

             1510      1520      1530      1540      1550      1560
pF1KA0 NGSETQLNKFYTKKCRELYYCVKDSMERAAARQQSIKPGPELGGEFPVQDLKTGEGGLLQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 NGSETQLNKFYTKKCRELYYCVKDSMERAAARQQSIKPGPELGGEFPVQDLKTGEGGLLQ
    1500      1510      1520      1530      1540      1550         

             1570      1580 
pF1KA0 VTLEGINLKFMHNQFLKLKKW
       :::::::::::::::::::::
XP_005 VTLEGINLKFMHNQFLKLKKW
    1560      1570      1580

>>XP_016873977 (OMIM: 603584) PREDICTED: MAP kinase-acti  (1577 aa)
 initn: 7914 init1: 7914 opt: 10425  Z-score: 9025.2  bits: 1682.8 E(85289):    0
Smith-Waterman score: 10425; 99.7% identity (99.7% similar) in 1581 aa overlap (1-1581:1-1577)

               10        20        30        40        50        60
pF1KA0 MVQKKKFCPRLLDYLVIVGARHPSSDSVAQTPELLRRYPLEDHTEFPLPPDVVFFCQPEG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MVQKKKFCPRLLDYLVIVGARHPSSDSVAQTPELLRRYPLEDHTEFPLPPDVVFFCQPEG
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KA0 CLSVRQRRMSLRDDTSFVFTLTDKDTGVTRYGICVNFYRSFQKRISKEKGEGGAGSRGKE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 CLSVRQRRMSLRDDTSFVFTLTDKDTGVTRYGICVNFYRSFQKRISKEKGEGGAGSRGKE
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KA0 GTHATCASEEGGTESSESGSSLQPLSADSTPDVNQSPRGKRRAKAGSRSRNSTLTSLCVL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GTHATCASEEGGTESSESGSSLQPLSADSTPDVNQSPRGKRRAKAGSRSRNSTLTSLCVL
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KA0 SHYPFFSTFRECLYTLKRLVDCCSERLLGKKLGIPRGVQRDTMWRIFTGSLLVEEKSSAL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SHYPFFSTFRECLYTLKRLVDCCSERLLGKKLGIPRGVQRDTMWRIFTGSLLVEEKSSAL
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KA0 LHDLREIEAWIYRLLRSPVPVSGQKRVDIEVLPQELQPALTFALPDPSRFTLVDFPLHLP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LHDLREIEAWIYRLLRSPVPVSGQKRVDIEVLPQELQPALTFALPDPSRFTLVDFPLHLP
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KA0 LELLGVDACLQVLTCILLEHKVVLQSRDYNALSMSVMAFVAMIYPLEYMFPVIPLLPTCM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LELLGVDACLQVLTCILLEHKVVLQSRDYNALSMSVMAFVAMIYPLEYMFPVIPLLPTCM
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KA0 ASAEQLLLAPTPYIIGVPASFFLYKLDFKMPDDVWLVDLDSNRVIAPTNAEVLPILPEPE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ASAEQLLLAPTPYIIGVPASFFLYKLDFKMPDDVWLVDLDSNRVIAPTNAEVLPILPEPE
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KA0 SLELKKHLKQALASMSLNTQPILNLEKFHEGQEIPLLLGRPSNDLQSTPSTEFNPLIYGN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SLELKKHLKQALASMSLNTQPILNLEKFHEGQEIPLLLGRPSNDLQSTPSTEFNPLIYGN
              430       440       450       460       470       480

              490       500       510       520       530       540
pF1KA0 DVDSVDVATRVAMVRFFNSANVLQGFQMHTRTLRLFPRPVVAFQAGSFLASRPRQTPFAE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DVDSVDVATRVAMVRFFNSANVLQGFQMHTRTLRLFPRPVVAFQAGSFLASRPRQTPFAE
              490       500       510       520       530       540

              550       560       570       580       590       600
pF1KA0 KLARTQAVEYFGEWILNPTNYAFQRIHNNMFDPALIGDKPKWYAHQLQPIHYRVYDSNSQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KLARTQAVEYFGEWILNPTNYAFQRIHNNMFDPALIGDKPKWYAHQLQPIHYRVYDSNSQ
              550       560       570       580       590       600

              610       620       630       640       650       660
pF1KA0 LAEALSVPPERDSDSEPTDDSGSDSMDYDDSSSSYSSLGDFVSEMMKCDINGDTPNVDPL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LAEALSVPPERDSDSEPTDDSGSDSMDYDDSSSSYSSLGDFVSEMMKCDINGDTPNVDPL
              610       620       630       640       650       660

              670       680       690       700       710       720
pF1KA0 THAALGDASEVEIDELQNQKEAEEPGPDSENSQENPPLRSSSSTTASSSPSTVIHGANSE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 THAALGDASEVEIDELQNQKEAEEPGPDSENSQENPPLRSSSSTTASSSPSTVIHGANSE
              670       680       690       700       710       720

              730       740       750       760       770       780
pF1KA0 PADSTEMDDKAAVGVSKPLPSVPPSIGKSNVDRRQAEIGEGSVRRRIYDNPYFEPQYGFP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PADSTEMDDKAAVGVSKPLPSVPPSIGKSNVDRRQAEIGEGSVRRRIYDNPYFEPQYGFP
              730       740       750       760       770       780

              790       800       810       820       830       840
pF1KA0 PEEDEDEQGESYTPRFSQHVSGNRAQKLLRPNSLRLASDSDAESDSRASSPNSTVSNTST
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PEEDEDEQGESYTPRFSQHVSGNRAQKLLRPNSLRLASDSDAESDSRASSPNSTVSNTST
              790       800       810       820       830       840

              850       860       870       880       890       900
pF1KA0 EGFGGIMSFASSLYRNHSTSFSLSNLTLPTKGAREKATPFPSLKVFGLNTLMEIVTEAGP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EGFGGIMSFASSLYRNHSTSFSLSNLTLPTKGAREKATPFPSLKVFGLNTLMEIVTEAGP
              850       860       870       880       890       900

              910       920       930       940       950       960
pF1KA0 GSGEGNRRALVDQKSSVIKHSPTVKREPPSPQGRSSNSSENQQFLKEVVHSVLDGQGVGW
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GSGEGNRRALVDQKSSVIKHSPTVKREPPSPQGRSSNSSENQQFLKEVVHSVLDGQGVGW
              910       920       930       940       950       960

              970       980       990      1000      1010      1020
pF1KA0 LNMKKVRRLLESEQLRVFVLSKLNRMVQSEDDARQDIIPDVEISRKVYKGMLDLLKCTVL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LNMKKVRRLLESEQLRVFVLSKLNRMVQSEDDARQDIIPDVEISRKVYKGMLDLLKCTVL
              970       980       990      1000      1010      1020

             1030      1040      1050      1060      1070      1080
pF1KA0 SLEQSYAHAGLGGMASIFGLLEIAQTHYYSKEPDKRKRSPTESVNTPVGKDPGLAGRGDP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SLEQSYAHAGLGGMASIFGLLEIAQTHYYSKEPDKRKRSPTESVNTPVGKDPGLAGRGDP
             1030      1040      1050      1060      1070      1080

             1090      1100      1110      1120      1130      1140
pF1KA0 KAMAQLRVPQLGPRAPSATGKGPKELDTRSLKEENFIASIELWNKHQEVKKQKALEKQRP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KAMAQLRVPQLGPRAPSATGKGPKELDTRSLKEENFIASIELWNKHQEVKKQKALEKQRP
             1090      1100      1110      1120      1130      1140

             1150      1160      1170      1180      1190      1200
pF1KA0 EVIKPVFDLGETEEKKSQISADSGVSLTSSSQRTDQDSVIGVSPAVMIRSSSQDSEVSTV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::  
XP_016 EVIKPVFDLGETEEKKSQISADSGVSLTSSSQRTDQDSVIGVSPAVMIRSSSQDSEVS--
             1150      1160      1170      1180      1190          

             1210      1220      1230      1240      1250      1260
pF1KA0 VSNSSGETLGADSDLSSNAGDGPGGEGSVHLASSRGTLSDSEIETNSATSTIFGKAHSLK
         ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 --NSSGETLGADSDLSSNAGDGPGGEGSVHLASSRGTLSDSEIETNSATSTIFGKAHSLK
       1200      1210      1220      1230      1240      1250      

             1270      1280      1290      1300      1310      1320
pF1KA0 PSIKEKLAGSPIRTSEDVSQRVYLYEGLLGRDKGSMWDQLEDAAMETFSISKERSTLWDQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PSIKEKLAGSPIRTSEDVSQRVYLYEGLLGRDKGSMWDQLEDAAMETFSISKERSTLWDQ
       1260      1270      1280      1290      1300      1310      

             1330      1340      1350      1360      1370      1380
pF1KA0 MQFWEDAFLDAVMLEREGMGMDQGPQEMIDRYLSLGEHDRKRLEDDEDRLLATLLHNLIS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MQFWEDAFLDAVMLEREGMGMDQGPQEMIDRYLSLGEHDRKRLEDDEDRLLATLLHNLIS
       1320      1330      1340      1350      1360      1370      

             1390      1400      1410      1420      1430      1440
pF1KA0 YMLLMKVNKNDIRKKVRRLMGKSHIGLVYSQQINEVLDQLANLNGRDLSIWSSGSRHMKK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 YMLLMKVNKNDIRKKVRRLMGKSHIGLVYSQQINEVLDQLANLNGRDLSIWSSGSRHMKK
       1380      1390      1400      1410      1420      1430      

             1450      1460      1470      1480      1490      1500
pF1KA0 QTFVVHAGTDTNGDIFFMEVCDDCVVLRSNIGTVYERWWYEKLINMTYCPKTKVLCLWRR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QTFVVHAGTDTNGDIFFMEVCDDCVVLRSNIGTVYERWWYEKLINMTYCPKTKVLCLWRR
       1440      1450      1460      1470      1480      1490      

             1510      1520      1530      1540      1550      1560
pF1KA0 NGSETQLNKFYTKKCRELYYCVKDSMERAAARQQSIKPGPELGGEFPVQDLKTGEGGLLQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NGSETQLNKFYTKKCRELYYCVKDSMERAAARQQSIKPGPELGGEFPVQDLKTGEGGLLQ
       1500      1510      1520      1530      1540      1550      

             1570      1580 
pF1KA0 VTLEGINLKFMHNQFLKLKKW
       :::::::::::::::::::::
XP_016 VTLEGINLKFMHNQFLKLKKW
       1560      1570       

>>XP_016873978 (OMIM: 603584) PREDICTED: MAP kinase-acti  (1577 aa)
 initn: 7914 init1: 7914 opt: 10425  Z-score: 9025.2  bits: 1682.8 E(85289):    0
Smith-Waterman score: 10425; 99.7% identity (99.7% similar) in 1581 aa overlap (1-1581:1-1577)

               10        20        30        40        50        60
pF1KA0 MVQKKKFCPRLLDYLVIVGARHPSSDSVAQTPELLRRYPLEDHTEFPLPPDVVFFCQPEG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MVQKKKFCPRLLDYLVIVGARHPSSDSVAQTPELLRRYPLEDHTEFPLPPDVVFFCQPEG
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KA0 CLSVRQRRMSLRDDTSFVFTLTDKDTGVTRYGICVNFYRSFQKRISKEKGEGGAGSRGKE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 CLSVRQRRMSLRDDTSFVFTLTDKDTGVTRYGICVNFYRSFQKRISKEKGEGGAGSRGKE
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KA0 GTHATCASEEGGTESSESGSSLQPLSADSTPDVNQSPRGKRRAKAGSRSRNSTLTSLCVL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GTHATCASEEGGTESSESGSSLQPLSADSTPDVNQSPRGKRRAKAGSRSRNSTLTSLCVL
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KA0 SHYPFFSTFRECLYTLKRLVDCCSERLLGKKLGIPRGVQRDTMWRIFTGSLLVEEKSSAL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SHYPFFSTFRECLYTLKRLVDCCSERLLGKKLGIPRGVQRDTMWRIFTGSLLVEEKSSAL
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KA0 LHDLREIEAWIYRLLRSPVPVSGQKRVDIEVLPQELQPALTFALPDPSRFTLVDFPLHLP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LHDLREIEAWIYRLLRSPVPVSGQKRVDIEVLPQELQPALTFALPDPSRFTLVDFPLHLP
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KA0 LELLGVDACLQVLTCILLEHKVVLQSRDYNALSMSVMAFVAMIYPLEYMFPVIPLLPTCM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LELLGVDACLQVLTCILLEHKVVLQSRDYNALSMSVMAFVAMIYPLEYMFPVIPLLPTCM
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KA0 ASAEQLLLAPTPYIIGVPASFFLYKLDFKMPDDVWLVDLDSNRVIAPTNAEVLPILPEPE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ASAEQLLLAPTPYIIGVPASFFLYKLDFKMPDDVWLVDLDSNRVIAPTNAEVLPILPEPE
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KA0 SLELKKHLKQALASMSLNTQPILNLEKFHEGQEIPLLLGRPSNDLQSTPSTEFNPLIYGN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SLELKKHLKQALASMSLNTQPILNLEKFHEGQEIPLLLGRPSNDLQSTPSTEFNPLIYGN
              430       440       450       460       470       480

              490       500       510       520       530       540
pF1KA0 DVDSVDVATRVAMVRFFNSANVLQGFQMHTRTLRLFPRPVVAFQAGSFLASRPRQTPFAE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DVDSVDVATRVAMVRFFNSANVLQGFQMHTRTLRLFPRPVVAFQAGSFLASRPRQTPFAE
              490       500       510       520       530       540

              550       560       570       580       590       600
pF1KA0 KLARTQAVEYFGEWILNPTNYAFQRIHNNMFDPALIGDKPKWYAHQLQPIHYRVYDSNSQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KLARTQAVEYFGEWILNPTNYAFQRIHNNMFDPALIGDKPKWYAHQLQPIHYRVYDSNSQ
              550       560       570       580       590       600

              610       620       630       640       650       660
pF1KA0 LAEALSVPPERDSDSEPTDDSGSDSMDYDDSSSSYSSLGDFVSEMMKCDINGDTPNVDPL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LAEALSVPPERDSDSEPTDDSGSDSMDYDDSSSSYSSLGDFVSEMMKCDINGDTPNVDPL
              610       620       630       640       650       660

              670       680       690       700       710       720
pF1KA0 THAALGDASEVEIDELQNQKEAEEPGPDSENSQENPPLRSSSSTTASSSPSTVIHGANSE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 THAALGDASEVEIDELQNQKEAEEPGPDSENSQENPPLRSSSSTTASSSPSTVIHGANSE
              670       680       690       700       710       720

              730       740       750       760       770       780
pF1KA0 PADSTEMDDKAAVGVSKPLPSVPPSIGKSNVDRRQAEIGEGSVRRRIYDNPYFEPQYGFP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PADSTEMDDKAAVGVSKPLPSVPPSIGKSNVDRRQAEIGEGSVRRRIYDNPYFEPQYGFP
              730       740       750       760       770       780

              790       800       810       820       830       840
pF1KA0 PEEDEDEQGESYTPRFSQHVSGNRAQKLLRPNSLRLASDSDAESDSRASSPNSTVSNTST
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PEEDEDEQGESYTPRFSQHVSGNRAQKLLRPNSLRLASDSDAESDSRASSPNSTVSNTST
              790       800       810       820       830       840

              850       860       870       880       890       900
pF1KA0 EGFGGIMSFASSLYRNHSTSFSLSNLTLPTKGAREKATPFPSLKVFGLNTLMEIVTEAGP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EGFGGIMSFASSLYRNHSTSFSLSNLTLPTKGAREKATPFPSLKVFGLNTLMEIVTEAGP
              850       860       870       880       890       900

              910       920       930       940       950       960
pF1KA0 GSGEGNRRALVDQKSSVIKHSPTVKREPPSPQGRSSNSSENQQFLKEVVHSVLDGQGVGW
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GSGEGNRRALVDQKSSVIKHSPTVKREPPSPQGRSSNSSENQQFLKEVVHSVLDGQGVGW
              910       920       930       940       950       960

              970       980       990      1000      1010      1020
pF1KA0 LNMKKVRRLLESEQLRVFVLSKLNRMVQSEDDARQDIIPDVEISRKVYKGMLDLLKCTVL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LNMKKVRRLLESEQLRVFVLSKLNRMVQSEDDARQDIIPDVEISRKVYKGMLDLLKCTVL
              970       980       990      1000      1010      1020

             1030      1040      1050      1060      1070      1080
pF1KA0 SLEQSYAHAGLGGMASIFGLLEIAQTHYYSKEPDKRKRSPTESVNTPVGKDPGLAGRGDP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SLEQSYAHAGLGGMASIFGLLEIAQTHYYSKEPDKRKRSPTESVNTPVGKDPGLAGRGDP
             1030      1040      1050      1060      1070      1080

             1090      1100      1110      1120      1130      1140
pF1KA0 KAMAQLRVPQLGPRAPSATGKGPKELDTRSLKEENFIASIELWNKHQEVKKQKALEKQRP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KAMAQLRVPQLGPRAPSATGKGPKELDTRSLKEENFIASIELWNKHQEVKKQKALEKQRP
             1090      1100      1110      1120      1130      1140

             1150      1160      1170      1180      1190      1200
pF1KA0 EVIKPVFDLGETEEKKSQISADSGVSLTSSSQRTDQDSVIGVSPAVMIRSSSQDSEVSTV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::  
XP_016 EVIKPVFDLGETEEKKSQISADSGVSLTSSSQRTDQDSVIGVSPAVMIRSSSQDSEVS--
             1150      1160      1170      1180      1190          

             1210      1220      1230      1240      1250      1260
pF1KA0 VSNSSGETLGADSDLSSNAGDGPGGEGSVHLASSRGTLSDSEIETNSATSTIFGKAHSLK
         ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 --NSSGETLGADSDLSSNAGDGPGGEGSVHLASSRGTLSDSEIETNSATSTIFGKAHSLK
       1200      1210      1220      1230      1240      1250      

             1270      1280      1290      1300      1310      1320
pF1KA0 PSIKEKLAGSPIRTSEDVSQRVYLYEGLLGRDKGSMWDQLEDAAMETFSISKERSTLWDQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PSIKEKLAGSPIRTSEDVSQRVYLYEGLLGRDKGSMWDQLEDAAMETFSISKERSTLWDQ
       1260      1270      1280      1290      1300      1310      

             1330      1340      1350      1360      1370      1380
pF1KA0 MQFWEDAFLDAVMLEREGMGMDQGPQEMIDRYLSLGEHDRKRLEDDEDRLLATLLHNLIS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MQFWEDAFLDAVMLEREGMGMDQGPQEMIDRYLSLGEHDRKRLEDDEDRLLATLLHNLIS
       1320      1330      1340      1350      1360      1370      

             1390      1400      1410      1420      1430      1440
pF1KA0 YMLLMKVNKNDIRKKVRRLMGKSHIGLVYSQQINEVLDQLANLNGRDLSIWSSGSRHMKK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 YMLLMKVNKNDIRKKVRRLMGKSHIGLVYSQQINEVLDQLANLNGRDLSIWSSGSRHMKK
       1380      1390      1400      1410      1420      1430      

             1450      1460      1470      1480      1490      1500
pF1KA0 QTFVVHAGTDTNGDIFFMEVCDDCVVLRSNIGTVYERWWYEKLINMTYCPKTKVLCLWRR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QTFVVHAGTDTNGDIFFMEVCDDCVVLRSNIGTVYERWWYEKLINMTYCPKTKVLCLWRR
       1440      1450      1460      1470      1480      1490      

             1510      1520      1530      1540      1550      1560
pF1KA0 NGSETQLNKFYTKKCRELYYCVKDSMERAAARQQSIKPGPELGGEFPVQDLKTGEGGLLQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NGSETQLNKFYTKKCRELYYCVKDSMERAAARQQSIKPGPELGGEFPVQDLKTGEGGLLQ
       1500      1510      1520      1530      1540      1550      

             1570      1580 
pF1KA0 VTLEGINLKFMHNQFLKLKKW
       :::::::::::::::::::::
XP_016 VTLEGINLKFMHNQFLKLKKW
       1560      1570       

>>NP_003673 (OMIM: 603584) MAP kinase-activating death d  (1647 aa)
 initn: 10412 init1: 10412 opt: 10416  Z-score: 9017.1  bits: 1681.4 E(85289):    0
Smith-Waterman score: 10416; 99.8% identity (99.9% similar) in 1579 aa overlap (1-1578:1-1579)

               10        20        30        40        50        60
pF1KA0 MVQKKKFCPRLLDYLVIVGARHPSSDSVAQTPELLRRYPLEDHTEFPLPPDVVFFCQPEG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 MVQKKKFCPRLLDYLVIVGARHPSSDSVAQTPELLRRYPLEDHTEFPLPPDVVFFCQPEG
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KA0 CLSVRQRRMSLRDDTSFVFTLTDKDTGVTRYGICVNFYRSFQKRISKEKGEGGAGSRGKE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 CLSVRQRRMSLRDDTSFVFTLTDKDTGVTRYGICVNFYRSFQKRISKEKGEGGAGSRGKE
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KA0 GTHATCASEEGGTESSESGSSLQPLSADSTPDVNQSPRGKRRAKAGSRSRNSTLTSLCVL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 GTHATCASEEGGTESSESGSSLQPLSADSTPDVNQSPRGKRRAKAGSRSRNSTLTSLCVL
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KA0 SHYPFFSTFRECLYTLKRLVDCCSERLLGKKLGIPRGVQRDTMWRIFTGSLLVEEKSSAL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 SHYPFFSTFRECLYTLKRLVDCCSERLLGKKLGIPRGVQRDTMWRIFTGSLLVEEKSSAL
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KA0 LHDLREIEAWIYRLLRSPVPVSGQKRVDIEVLPQELQPALTFALPDPSRFTLVDFPLHLP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 LHDLREIEAWIYRLLRSPVPVSGQKRVDIEVLPQELQPALTFALPDPSRFTLVDFPLHLP
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KA0 LELLGVDACLQVLTCILLEHKVVLQSRDYNALSMSVMAFVAMIYPLEYMFPVIPLLPTCM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 LELLGVDACLQVLTCILLEHKVVLQSRDYNALSMSVMAFVAMIYPLEYMFPVIPLLPTCM
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KA0 ASAEQLLLAPTPYIIGVPASFFLYKLDFKMPDDVWLVDLDSNRVIAPTNAEVLPILPEPE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 ASAEQLLLAPTPYIIGVPASFFLYKLDFKMPDDVWLVDLDSNRVIAPTNAEVLPILPEPE
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KA0 SLELKKHLKQALASMSLNTQPILNLEKFHEGQEIPLLLGRPSNDLQSTPSTEFNPLIYGN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 SLELKKHLKQALASMSLNTQPILNLEKFHEGQEIPLLLGRPSNDLQSTPSTEFNPLIYGN
              430       440       450       460       470       480

              490       500       510       520       530       540
pF1KA0 DVDSVDVATRVAMVRFFNSANVLQGFQMHTRTLRLFPRPVVAFQAGSFLASRPRQTPFAE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 DVDSVDVATRVAMVRFFNSANVLQGFQMHTRTLRLFPRPVVAFQAGSFLASRPRQTPFAE
              490       500       510       520       530       540

              550       560       570       580       590       600
pF1KA0 KLARTQAVEYFGEWILNPTNYAFQRIHNNMFDPALIGDKPKWYAHQLQPIHYRVYDSNSQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 KLARTQAVEYFGEWILNPTNYAFQRIHNNMFDPALIGDKPKWYAHQLQPIHYRVYDSNSQ
              550       560       570       580       590       600

              610       620       630       640       650       660
pF1KA0 LAEALSVPPERDSDSEPTDDSGSDSMDYDDSSSSYSSLGDFVSEMMKCDINGDTPNVDPL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 LAEALSVPPERDSDSEPTDDSGSDSMDYDDSSSSYSSLGDFVSEMMKCDINGDTPNVDPL
              610       620       630       640       650       660

              670       680       690       700       710       720
pF1KA0 THAALGDASEVEIDELQNQKEAEEPGPDSENSQENPPLRSSSSTTASSSPSTVIHGANSE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 THAALGDASEVEIDELQNQKEAEEPGPDSENSQENPPLRSSSSTTASSSPSTVIHGANSE
              670       680       690       700       710       720

              730       740       750       760       770       780
pF1KA0 PADSTEMDDKAAVGVSKPLPSVPPSIGKSNVDRRQAEIGEGSVRRRIYDNPYFEPQYGFP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 PADSTEMDDKAAVGVSKPLPSVPPSIGKSNVDRRQAEIGEGSVRRRIYDNPYFEPQYGFP
              730       740       750       760       770       780

              790       800       810       820       830       840
pF1KA0 PEEDEDEQGESYTPRFSQHVSGNRAQKLLRPNSLRLASDSDAESDSRASSPNSTVSNTST
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 PEEDEDEQGESYTPRFSQHVSGNRAQKLLRPNSLRLASDSDAESDSRASSPNSTVSNTST
              790       800       810       820       830       840

              850       860       870       880       890       900
pF1KA0 EGFGGIMSFASSLYRNHSTSFSLSNLTLPTKGAREKATPFPSLKVFGLNTLMEIVTEAGP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 EGFGGIMSFASSLYRNHSTSFSLSNLTLPTKGAREKATPFPSLKVFGLNTLMEIVTEAGP
              850       860       870       880       890       900

              910       920       930       940       950       960
pF1KA0 GSGEGNRRALVDQKSSVIKHSPTVKREPPSPQGRSSNSSENQQFLKEVVHSVLDGQGVGW
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 GSGEGNRRALVDQKSSVIKHSPTVKREPPSPQGRSSNSSENQQFLKEVVHSVLDGQGVGW
              910       920       930       940       950       960

              970       980       990      1000      1010      1020
pF1KA0 LNMKKVRRLLESEQLRVFVLSKLNRMVQSEDDARQDIIPDVEISRKVYKGMLDLLKCTVL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 LNMKKVRRLLESEQLRVFVLSKLNRMVQSEDDARQDIIPDVEISRKVYKGMLDLLKCTVL
              970       980       990      1000      1010      1020

             1030      1040      1050      1060      1070      1080
pF1KA0 SLEQSYAHAGLGGMASIFGLLEIAQTHYYSKEPDKRKRSPTESVNTPVGKDPGLAGRGDP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 SLEQSYAHAGLGGMASIFGLLEIAQTHYYSKEPDKRKRSPTESVNTPVGKDPGLAGRGDP
             1030      1040      1050      1060      1070      1080

             1090      1100      1110      1120      1130      1140
pF1KA0 KAMAQLRVPQLGPRAPSATGKGPKELDTRSLKEENFIASIELWNKHQEVKKQKALEKQRP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 KAMAQLRVPQLGPRAPSATGKGPKELDTRSLKEENFIASIELWNKHQEVKKQKALEKQRP
             1090      1100      1110      1120      1130      1140

             1150      1160      1170      1180      1190      1200
pF1KA0 EVIKPVFDLGETEEKKSQISADSGVSLTSSSQRTDQDSVIGVSPAVMIRSSSQDSEVSTV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 EVIKPVFDLGETEEKKSQISADSGVSLTSSSQRTDQDSVIGVSPAVMIRSSSQDSEVSTV
             1150      1160      1170      1180      1190      1200

             1210      1220      1230      1240      1250      1260
pF1KA0 VSNSSGETLGADSDLSSNAGDGPGGEGSVHLASSRGTLSDSEIETNSATSTIFGKAHSLK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 VSNSSGETLGADSDLSSNAGDGPGGEGSVHLASSRGTLSDSEIETNSATSTIFGKAHSLK
             1210      1220      1230      1240      1250      1260

             1270      1280      1290      1300      1310      1320
pF1KA0 PSIKEKLAGSPIRTSEDVSQRVYLYEGLLGRDKGSMWDQLEDAAMETFSISKERSTLWDQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 PSIKEKLAGSPIRTSEDVSQRVYLYEGLLGRDKGSMWDQLEDAAMETFSISKERSTLWDQ
             1270      1280      1290      1300      1310      1320

             1330      1340      1350      1360      1370      1380
pF1KA0 MQFWEDAFLDAVMLEREGMGMDQGPQEMIDRYLSLGEHDRKRLEDDEDRLLATLLHNLIS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 MQFWEDAFLDAVMLEREGMGMDQGPQEMIDRYLSLGEHDRKRLEDDEDRLLATLLHNLIS
             1330      1340      1350      1360      1370      1380

             1390      1400      1410      1420      1430      1440
pF1KA0 YMLLMKVNKNDIRKKVRRLMGKSHIGLVYSQQINEVLDQLANLNGRDLSIWSSGSRHMKK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 YMLLMKVNKNDIRKKVRRLMGKSHIGLVYSQQINEVLDQLANLNGRDLSIWSSGSRHMKK
             1390      1400      1410      1420      1430      1440

             1450      1460      1470      1480      1490      1500
pF1KA0 QTFVVHAGTDTNGDIFFMEVCDDCVVLRSNIGTVYERWWYEKLINMTYCPKTKVLCLWRR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 QTFVVHAGTDTNGDIFFMEVCDDCVVLRSNIGTVYERWWYEKLINMTYCPKTKVLCLWRR
             1450      1460      1470      1480      1490      1500

             1510      1520      1530      1540      1550      1560
pF1KA0 NGSETQLNKFYTKKCRELYYCVKDSMERAAARQQSIKPGPELGGEFPVQDLKTGEGGLLQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 NGSETQLNKFYTKKCRELYYCVKDSMERAAARQQSIKPGPELGGEFPVQDLKTGEGGLLQ
             1510      1520      1530      1540      1550      1560

             1570       1580                                       
pF1KA0 VTLEGINLKFMHNQ-FLKLKKW                                      
       :::::::::::::: :..:                                         
NP_003 VTLEGINLKFMHNQVFIELNHIKKCNTVRGVFVLEEFVPEIKEVVSHKYKTPMAHEICYS
             1570      1580      1590      1600      1610      1620

>>XP_005253246 (OMIM: 603584) PREDICTED: MAP kinase-acti  (1647 aa)
 initn: 10412 init1: 10412 opt: 10416  Z-score: 9017.1  bits: 1681.4 E(85289):    0
Smith-Waterman score: 10416; 99.8% identity (99.9% similar) in 1579 aa overlap (1-1578:1-1579)

               10        20        30        40        50        60
pF1KA0 MVQKKKFCPRLLDYLVIVGARHPSSDSVAQTPELLRRYPLEDHTEFPLPPDVVFFCQPEG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MVQKKKFCPRLLDYLVIVGARHPSSDSVAQTPELLRRYPLEDHTEFPLPPDVVFFCQPEG
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KA0 CLSVRQRRMSLRDDTSFVFTLTDKDTGVTRYGICVNFYRSFQKRISKEKGEGGAGSRGKE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 CLSVRQRRMSLRDDTSFVFTLTDKDTGVTRYGICVNFYRSFQKRISKEKGEGGAGSRGKE
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KA0 GTHATCASEEGGTESSESGSSLQPLSADSTPDVNQSPRGKRRAKAGSRSRNSTLTSLCVL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 GTHATCASEEGGTESSESGSSLQPLSADSTPDVNQSPRGKRRAKAGSRSRNSTLTSLCVL
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KA0 SHYPFFSTFRECLYTLKRLVDCCSERLLGKKLGIPRGVQRDTMWRIFTGSLLVEEKSSAL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SHYPFFSTFRECLYTLKRLVDCCSERLLGKKLGIPRGVQRDTMWRIFTGSLLVEEKSSAL
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KA0 LHDLREIEAWIYRLLRSPVPVSGQKRVDIEVLPQELQPALTFALPDPSRFTLVDFPLHLP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LHDLREIEAWIYRLLRSPVPVSGQKRVDIEVLPQELQPALTFALPDPSRFTLVDFPLHLP
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KA0 LELLGVDACLQVLTCILLEHKVVLQSRDYNALSMSVMAFVAMIYPLEYMFPVIPLLPTCM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LELLGVDACLQVLTCILLEHKVVLQSRDYNALSMSVMAFVAMIYPLEYMFPVIPLLPTCM
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KA0 ASAEQLLLAPTPYIIGVPASFFLYKLDFKMPDDVWLVDLDSNRVIAPTNAEVLPILPEPE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 ASAEQLLLAPTPYIIGVPASFFLYKLDFKMPDDVWLVDLDSNRVIAPTNAEVLPILPEPE
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KA0 SLELKKHLKQALASMSLNTQPILNLEKFHEGQEIPLLLGRPSNDLQSTPSTEFNPLIYGN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SLELKKHLKQALASMSLNTQPILNLEKFHEGQEIPLLLGRPSNDLQSTPSTEFNPLIYGN
              430       440       450       460       470       480

              490       500       510       520       530       540
pF1KA0 DVDSVDVATRVAMVRFFNSANVLQGFQMHTRTLRLFPRPVVAFQAGSFLASRPRQTPFAE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 DVDSVDVATRVAMVRFFNSANVLQGFQMHTRTLRLFPRPVVAFQAGSFLASRPRQTPFAE
              490       500       510       520       530       540

              550       560       570       580       590       600
pF1KA0 KLARTQAVEYFGEWILNPTNYAFQRIHNNMFDPALIGDKPKWYAHQLQPIHYRVYDSNSQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 KLARTQAVEYFGEWILNPTNYAFQRIHNNMFDPALIGDKPKWYAHQLQPIHYRVYDSNSQ
              550       560       570       580       590       600

              610       620       630       640       650       660
pF1KA0 LAEALSVPPERDSDSEPTDDSGSDSMDYDDSSSSYSSLGDFVSEMMKCDINGDTPNVDPL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LAEALSVPPERDSDSEPTDDSGSDSMDYDDSSSSYSSLGDFVSEMMKCDINGDTPNVDPL
              610       620       630       640       650       660

              670       680       690       700       710       720
pF1KA0 THAALGDASEVEIDELQNQKEAEEPGPDSENSQENPPLRSSSSTTASSSPSTVIHGANSE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 THAALGDASEVEIDELQNQKEAEEPGPDSENSQENPPLRSSSSTTASSSPSTVIHGANSE
              670       680       690       700       710       720

              730       740       750       760       770       780
pF1KA0 PADSTEMDDKAAVGVSKPLPSVPPSIGKSNVDRRQAEIGEGSVRRRIYDNPYFEPQYGFP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 PADSTEMDDKAAVGVSKPLPSVPPSIGKSNVDRRQAEIGEGSVRRRIYDNPYFEPQYGFP
              730       740       750       760       770       780

              790       800       810       820       830       840
pF1KA0 PEEDEDEQGESYTPRFSQHVSGNRAQKLLRPNSLRLASDSDAESDSRASSPNSTVSNTST
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 PEEDEDEQGESYTPRFSQHVSGNRAQKLLRPNSLRLASDSDAESDSRASSPNSTVSNTST
              790       800       810       820       830       840

              850       860       870       880       890       900
pF1KA0 EGFGGIMSFASSLYRNHSTSFSLSNLTLPTKGAREKATPFPSLKVFGLNTLMEIVTEAGP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 EGFGGIMSFASSLYRNHSTSFSLSNLTLPTKGAREKATPFPSLKVFGLNTLMEIVTEAGP
              850       860       870       880       890       900

              910       920       930       940       950       960
pF1KA0 GSGEGNRRALVDQKSSVIKHSPTVKREPPSPQGRSSNSSENQQFLKEVVHSVLDGQGVGW
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 GSGEGNRRALVDQKSSVIKHSPTVKREPPSPQGRSSNSSENQQFLKEVVHSVLDGQGVGW
              910       920       930       940       950       960

              970       980       990      1000      1010      1020
pF1KA0 LNMKKVRRLLESEQLRVFVLSKLNRMVQSEDDARQDIIPDVEISRKVYKGMLDLLKCTVL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LNMKKVRRLLESEQLRVFVLSKLNRMVQSEDDARQDIIPDVEISRKVYKGMLDLLKCTVL
              970       980       990      1000      1010      1020

             1030      1040      1050      1060      1070      1080
pF1KA0 SLEQSYAHAGLGGMASIFGLLEIAQTHYYSKEPDKRKRSPTESVNTPVGKDPGLAGRGDP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SLEQSYAHAGLGGMASIFGLLEIAQTHYYSKEPDKRKRSPTESVNTPVGKDPGLAGRGDP
             1030      1040      1050      1060      1070      1080

             1090      1100      1110      1120      1130      1140
pF1KA0 KAMAQLRVPQLGPRAPSATGKGPKELDTRSLKEENFIASIELWNKHQEVKKQKALEKQRP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 KAMAQLRVPQLGPRAPSATGKGPKELDTRSLKEENFIASIELWNKHQEVKKQKALEKQRP
             1090      1100      1110      1120      1130      1140

             1150      1160      1170      1180      1190      1200
pF1KA0 EVIKPVFDLGETEEKKSQISADSGVSLTSSSQRTDQDSVIGVSPAVMIRSSSQDSEVSTV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 EVIKPVFDLGETEEKKSQISADSGVSLTSSSQRTDQDSVIGVSPAVMIRSSSQDSEVSTV
             1150      1160      1170      1180      1190      1200

             1210      1220      1230      1240      1250      1260
pF1KA0 VSNSSGETLGADSDLSSNAGDGPGGEGSVHLASSRGTLSDSEIETNSATSTIFGKAHSLK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 VSNSSGETLGADSDLSSNAGDGPGGEGSVHLASSRGTLSDSEIETNSATSTIFGKAHSLK
             1210      1220      1230      1240      1250      1260

             1270      1280      1290      1300      1310      1320
pF1KA0 PSIKEKLAGSPIRTSEDVSQRVYLYEGLLGRDKGSMWDQLEDAAMETFSISKERSTLWDQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 PSIKEKLAGSPIRTSEDVSQRVYLYEGLLGRDKGSMWDQLEDAAMETFSISKERSTLWDQ
             1270      1280      1290      1300      1310      1320

             1330      1340      1350      1360      1370      1380
pF1KA0 MQFWEDAFLDAVMLEREGMGMDQGPQEMIDRYLSLGEHDRKRLEDDEDRLLATLLHNLIS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MQFWEDAFLDAVMLEREGMGMDQGPQEMIDRYLSLGEHDRKRLEDDEDRLLATLLHNLIS
             1330      1340      1350      1360      1370      1380

             1390      1400      1410      1420      1430      1440
pF1KA0 YMLLMKVNKNDIRKKVRRLMGKSHIGLVYSQQINEVLDQLANLNGRDLSIWSSGSRHMKK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 YMLLMKVNKNDIRKKVRRLMGKSHIGLVYSQQINEVLDQLANLNGRDLSIWSSGSRHMKK
             1390      1400      1410      1420      1430      1440

             1450      1460      1470      1480      1490      1500
pF1KA0 QTFVVHAGTDTNGDIFFMEVCDDCVVLRSNIGTVYERWWYEKLINMTYCPKTKVLCLWRR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 QTFVVHAGTDTNGDIFFMEVCDDCVVLRSNIGTVYERWWYEKLINMTYCPKTKVLCLWRR
             1450      1460      1470      1480      1490      1500

             1510      1520      1530      1540      1550      1560
pF1KA0 NGSETQLNKFYTKKCRELYYCVKDSMERAAARQQSIKPGPELGGEFPVQDLKTGEGGLLQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 NGSETQLNKFYTKKCRELYYCVKDSMERAAARQQSIKPGPELGGEFPVQDLKTGEGGLLQ
             1510      1520      1530      1540      1550      1560

             1570       1580                                       
pF1KA0 VTLEGINLKFMHNQ-FLKLKKW                                      
       :::::::::::::: :..:                                         
XP_005 VTLEGINLKFMHNQVFIELNHIKKCNTVRGVFVLEEFVPEIKEVVSHKYKTPMAHEICYS
             1570      1580      1590      1600      1610      1620

>>XP_016873967 (OMIM: 603584) PREDICTED: MAP kinase-acti  (1643 aa)
 initn: 7914 init1: 7914 opt: 10378  Z-score: 8984.2  bits: 1675.3 E(85289):    0
Smith-Waterman score: 10378; 99.6% identity (99.7% similar) in 1579 aa overlap (1-1578:1-1575)

               10        20        30        40        50        60
pF1KA0 MVQKKKFCPRLLDYLVIVGARHPSSDSVAQTPELLRRYPLEDHTEFPLPPDVVFFCQPEG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MVQKKKFCPRLLDYLVIVGARHPSSDSVAQTPELLRRYPLEDHTEFPLPPDVVFFCQPEG
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KA0 CLSVRQRRMSLRDDTSFVFTLTDKDTGVTRYGICVNFYRSFQKRISKEKGEGGAGSRGKE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 CLSVRQRRMSLRDDTSFVFTLTDKDTGVTRYGICVNFYRSFQKRISKEKGEGGAGSRGKE
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KA0 GTHATCASEEGGTESSESGSSLQPLSADSTPDVNQSPRGKRRAKAGSRSRNSTLTSLCVL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GTHATCASEEGGTESSESGSSLQPLSADSTPDVNQSPRGKRRAKAGSRSRNSTLTSLCVL
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KA0 SHYPFFSTFRECLYTLKRLVDCCSERLLGKKLGIPRGVQRDTMWRIFTGSLLVEEKSSAL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SHYPFFSTFRECLYTLKRLVDCCSERLLGKKLGIPRGVQRDTMWRIFTGSLLVEEKSSAL
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KA0 LHDLREIEAWIYRLLRSPVPVSGQKRVDIEVLPQELQPALTFALPDPSRFTLVDFPLHLP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LHDLREIEAWIYRLLRSPVPVSGQKRVDIEVLPQELQPALTFALPDPSRFTLVDFPLHLP
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KA0 LELLGVDACLQVLTCILLEHKVVLQSRDYNALSMSVMAFVAMIYPLEYMFPVIPLLPTCM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LELLGVDACLQVLTCILLEHKVVLQSRDYNALSMSVMAFVAMIYPLEYMFPVIPLLPTCM
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KA0 ASAEQLLLAPTPYIIGVPASFFLYKLDFKMPDDVWLVDLDSNRVIAPTNAEVLPILPEPE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ASAEQLLLAPTPYIIGVPASFFLYKLDFKMPDDVWLVDLDSNRVIAPTNAEVLPILPEPE
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KA0 SLELKKHLKQALASMSLNTQPILNLEKFHEGQEIPLLLGRPSNDLQSTPSTEFNPLIYGN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SLELKKHLKQALASMSLNTQPILNLEKFHEGQEIPLLLGRPSNDLQSTPSTEFNPLIYGN
              430       440       450       460       470       480

              490       500       510       520       530       540
pF1KA0 DVDSVDVATRVAMVRFFNSANVLQGFQMHTRTLRLFPRPVVAFQAGSFLASRPRQTPFAE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DVDSVDVATRVAMVRFFNSANVLQGFQMHTRTLRLFPRPVVAFQAGSFLASRPRQTPFAE
              490       500       510       520       530       540

              550       560       570       580       590       600
pF1KA0 KLARTQAVEYFGEWILNPTNYAFQRIHNNMFDPALIGDKPKWYAHQLQPIHYRVYDSNSQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KLARTQAVEYFGEWILNPTNYAFQRIHNNMFDPALIGDKPKWYAHQLQPIHYRVYDSNSQ
              550       560       570       580       590       600

              610       620       630       640       650       660
pF1KA0 LAEALSVPPERDSDSEPTDDSGSDSMDYDDSSSSYSSLGDFVSEMMKCDINGDTPNVDPL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LAEALSVPPERDSDSEPTDDSGSDSMDYDDSSSSYSSLGDFVSEMMKCDINGDTPNVDPL
              610       620       630       640       650       660

              670       680       690       700       710       720
pF1KA0 THAALGDASEVEIDELQNQKEAEEPGPDSENSQENPPLRSSSSTTASSSPSTVIHGANSE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 THAALGDASEVEIDELQNQKEAEEPGPDSENSQENPPLRSSSSTTASSSPSTVIHGANSE
              670       680       690       700       710       720

              730       740       750       760       770       780
pF1KA0 PADSTEMDDKAAVGVSKPLPSVPPSIGKSNVDRRQAEIGEGSVRRRIYDNPYFEPQYGFP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PADSTEMDDKAAVGVSKPLPSVPPSIGKSNVDRRQAEIGEGSVRRRIYDNPYFEPQYGFP
              730       740       750       760       770       780

              790       800       810       820       830       840
pF1KA0 PEEDEDEQGESYTPRFSQHVSGNRAQKLLRPNSLRLASDSDAESDSRASSPNSTVSNTST
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PEEDEDEQGESYTPRFSQHVSGNRAQKLLRPNSLRLASDSDAESDSRASSPNSTVSNTST
              790       800       810       820       830       840

              850       860       870       880       890       900
pF1KA0 EGFGGIMSFASSLYRNHSTSFSLSNLTLPTKGAREKATPFPSLKVFGLNTLMEIVTEAGP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EGFGGIMSFASSLYRNHSTSFSLSNLTLPTKGAREKATPFPSLKVFGLNTLMEIVTEAGP
              850       860       870       880       890       900

              910       920       930       940       950       960
pF1KA0 GSGEGNRRALVDQKSSVIKHSPTVKREPPSPQGRSSNSSENQQFLKEVVHSVLDGQGVGW
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GSGEGNRRALVDQKSSVIKHSPTVKREPPSPQGRSSNSSENQQFLKEVVHSVLDGQGVGW
              910       920       930       940       950       960

              970       980       990      1000      1010      1020
pF1KA0 LNMKKVRRLLESEQLRVFVLSKLNRMVQSEDDARQDIIPDVEISRKVYKGMLDLLKCTVL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LNMKKVRRLLESEQLRVFVLSKLNRMVQSEDDARQDIIPDVEISRKVYKGMLDLLKCTVL
              970       980       990      1000      1010      1020

             1030      1040      1050      1060      1070      1080
pF1KA0 SLEQSYAHAGLGGMASIFGLLEIAQTHYYSKEPDKRKRSPTESVNTPVGKDPGLAGRGDP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SLEQSYAHAGLGGMASIFGLLEIAQTHYYSKEPDKRKRSPTESVNTPVGKDPGLAGRGDP
             1030      1040      1050      1060      1070      1080

             1090      1100      1110      1120      1130      1140
pF1KA0 KAMAQLRVPQLGPRAPSATGKGPKELDTRSLKEENFIASIELWNKHQEVKKQKALEKQRP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KAMAQLRVPQLGPRAPSATGKGPKELDTRSLKEENFIASIELWNKHQEVKKQKALEKQRP
             1090      1100      1110      1120      1130      1140

             1150      1160      1170      1180      1190      1200
pF1KA0 EVIKPVFDLGETEEKKSQISADSGVSLTSSSQRTDQDSVIGVSPAVMIRSSSQDSEVSTV
       :::::::::::::::::::::::::::::::::::::::::::::::::::::::::   
XP_016 EVIKPVFDLGETEEKKSQISADSGVSLTSSSQRTDQDSVIGVSPAVMIRSSSQDSEV---
             1150      1160      1170      1180      1190          

             1210      1220      1230      1240      1250      1260
pF1KA0 VSNSSGETLGADSDLSSNAGDGPGGEGSVHLASSRGTLSDSEIETNSATSTIFGKAHSLK
        :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 -SNSSGETLGADSDLSSNAGDGPGGEGSVHLASSRGTLSDSEIETNSATSTIFGKAHSLK
       1200      1210      1220      1230      1240      1250      

             1270      1280      1290      1300      1310      1320
pF1KA0 PSIKEKLAGSPIRTSEDVSQRVYLYEGLLGRDKGSMWDQLEDAAMETFSISKERSTLWDQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PSIKEKLAGSPIRTSEDVSQRVYLYEGLLGRDKGSMWDQLEDAAMETFSISKERSTLWDQ
       1260      1270      1280      1290      1300      1310      

             1330      1340      1350      1360      1370      1380
pF1KA0 MQFWEDAFLDAVMLEREGMGMDQGPQEMIDRYLSLGEHDRKRLEDDEDRLLATLLHNLIS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MQFWEDAFLDAVMLEREGMGMDQGPQEMIDRYLSLGEHDRKRLEDDEDRLLATLLHNLIS
       1320      1330      1340      1350      1360      1370      

             1390      1400      1410      1420      1430      1440
pF1KA0 YMLLMKVNKNDIRKKVRRLMGKSHIGLVYSQQINEVLDQLANLNGRDLSIWSSGSRHMKK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 YMLLMKVNKNDIRKKVRRLMGKSHIGLVYSQQINEVLDQLANLNGRDLSIWSSGSRHMKK
       1380      1390      1400      1410      1420      1430      

             1450      1460      1470      1480      1490      1500
pF1KA0 QTFVVHAGTDTNGDIFFMEVCDDCVVLRSNIGTVYERWWYEKLINMTYCPKTKVLCLWRR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QTFVVHAGTDTNGDIFFMEVCDDCVVLRSNIGTVYERWWYEKLINMTYCPKTKVLCLWRR
       1440      1450      1460      1470      1480      1490      

             1510      1520      1530      1540      1550      1560
pF1KA0 NGSETQLNKFYTKKCRELYYCVKDSMERAAARQQSIKPGPELGGEFPVQDLKTGEGGLLQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NGSETQLNKFYTKKCRELYYCVKDSMERAAARQQSIKPGPELGGEFPVQDLKTGEGGLLQ
       1500      1510      1520      1530      1540      1550      

             1570       1580                                       
pF1KA0 VTLEGINLKFMHNQ-FLKLKKW                                      
       :::::::::::::: :..:                                         
XP_016 VTLEGINLKFMHNQVFIELNHIKKCNTVRGVFVLEEFVPEIKEVVSHKYKTPMAHEICYS
       1560      1570      1580      1590      1600      1610      

>>XP_016873979 (OMIM: 603584) PREDICTED: MAP kinase-acti  (1563 aa)
 initn: 10321 init1: 7420 opt: 7477  Z-score: 6472.7  bits: 1210.5 E(85289):    0
Smith-Waterman score: 10286; 98.8% identity (98.8% similar) in 1581 aa overlap (1-1581:1-1563)

               10        20        30        40        50        60
pF1KA0 MVQKKKFCPRLLDYLVIVGARHPSSDSVAQTPELLRRYPLEDHTEFPLPPDVVFFCQPEG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MVQKKKFCPRLLDYLVIVGARHPSSDSVAQTPELLRRYPLEDHTEFPLPPDVVFFCQPEG
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KA0 CLSVRQRRMSLRDDTSFVFTLTDKDTGVTRYGICVNFYRSFQKRISKEKGEGGAGSRGKE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 CLSVRQRRMSLRDDTSFVFTLTDKDTGVTRYGICVNFYRSFQKRISKEKGEGGAGSRGKE
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KA0 GTHATCASEEGGTESSESGSSLQPLSADSTPDVNQSPRGKRRAKAGSRSRNSTLTSLCVL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GTHATCASEEGGTESSESGSSLQPLSADSTPDVNQSPRGKRRAKAGSRSRNSTLTSLCVL
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KA0 SHYPFFSTFRECLYTLKRLVDCCSERLLGKKLGIPRGVQRDTMWRIFTGSLLVEEKSSAL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SHYPFFSTFRECLYTLKRLVDCCSERLLGKKLGIPRGVQRDTMWRIFTGSLLVEEKSSAL
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KA0 LHDLREIEAWIYRLLRSPVPVSGQKRVDIEVLPQELQPALTFALPDPSRFTLVDFPLHLP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LHDLREIEAWIYRLLRSPVPVSGQKRVDIEVLPQELQPALTFALPDPSRFTLVDFPLHLP
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KA0 LELLGVDACLQVLTCILLEHKVVLQSRDYNALSMSVMAFVAMIYPLEYMFPVIPLLPTCM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LELLGVDACLQVLTCILLEHKVVLQSRDYNALSMSVMAFVAMIYPLEYMFPVIPLLPTCM
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KA0 ASAEQLLLAPTPYIIGVPASFFLYKLDFKMPDDVWLVDLDSNRVIAPTNAEVLPILPEPE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ASAEQLLLAPTPYIIGVPASFFLYKLDFKMPDDVWLVDLDSNRVIAPTNAEVLPILPEPE
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KA0 SLELKKHLKQALASMSLNTQPILNLEKFHEGQEIPLLLGRPSNDLQSTPSTEFNPLIYGN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SLELKKHLKQALASMSLNTQPILNLEKFHEGQEIPLLLGRPSNDLQSTPSTEFNPLIYGN
              430       440       450       460       470       480

              490       500       510       520       530       540
pF1KA0 DVDSVDVATRVAMVRFFNSANVLQGFQMHTRTLRLFPRPVVAFQAGSFLASRPRQTPFAE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DVDSVDVATRVAMVRFFNSANVLQGFQMHTRTLRLFPRPVVAFQAGSFLASRPRQTPFAE
              490       500       510       520       530       540

              550       560       570       580       590       600
pF1KA0 KLARTQAVEYFGEWILNPTNYAFQRIHNNMFDPALIGDKPKWYAHQLQPIHYRVYDSNSQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KLARTQAVEYFGEWILNPTNYAFQRIHNNMFDPALIGDKPKWYAHQLQPIHYRVYDSNSQ
              550       560       570       580       590       600

              610       620       630       640       650       660
pF1KA0 LAEALSVPPERDSDSEPTDDSGSDSMDYDDSSSSYSSLGDFVSEMMKCDINGDTPNVDPL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LAEALSVPPERDSDSEPTDDSGSDSMDYDDSSSSYSSLGDFVSEMMKCDINGDTPNVDPL
              610       620       630       640       650       660

              670       680       690       700       710       720
pF1KA0 THAALGDASEVEIDELQNQKEAEEPGPDSENSQENPPLRSSSSTTASSSPSTVIHGANSE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 THAALGDASEVEIDELQNQKEAEEPGPDSENSQENPPLRSSSSTTASSSPSTVIHGANSE
              670       680       690       700       710       720

              730       740       750       760       770       780
pF1KA0 PADSTEMDDKAAVGVSKPLPSVPPSIGKSNVDRRQAEIGEGSVRRRIYDNPYFEPQYGFP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PADSTEMDDKAAVGVSKPLPSVPPSIGKSNVDRRQAEIGEGSVRRRIYDNPYFEPQYGFP
              730       740       750       760       770       780

              790       800       810       820       830       840
pF1KA0 PEEDEDEQGESYTPRFSQHVSGNRAQKLLRPNSLRLASDSDAESDSRASSPNSTVSNTST
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PEEDEDEQGESYTPRFSQHVSGNRAQKLLRPNSLRLASDSDAESDSRASSPNSTVSNTST
              790       800       810       820       830       840

              850       860       870       880       890       900
pF1KA0 EGFGGIMSFASSLYRNHSTSFSLSNLTLPTKGAREKATPFPSLKVFGLNTLMEIVTEAGP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EGFGGIMSFASSLYRNHSTSFSLSNLTLPTKGAREKATPFPSLKVFGLNTLMEIVTEAGP
              850       860       870       880       890       900

              910       920       930       940       950       960
pF1KA0 GSGEGNRRALVDQKSSVIKHSPTVKREPPSPQGRSSNSSENQQFLKEVVHSVLDGQGVGW
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GSGEGNRRALVDQKSSVIKHSPTVKREPPSPQGRSSNSSENQQFLKEVVHSVLDGQGVGW
              910       920       930       940       950       960

              970       980       990      1000      1010      1020
pF1KA0 LNMKKVRRLLESEQLRVFVLSKLNRMVQSEDDARQDIIPDVEISRKVYKGMLDLLKCTVL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LNMKKVRRLLESEQLRVFVLSKLNRMVQSEDDARQDIIPDVEISRKVYKGMLDLLKCTVL
              970       980       990      1000      1010      1020

             1030      1040      1050      1060      1070      1080
pF1KA0 SLEQSYAHAGLGGMASIFGLLEIAQTHYYSKEPDKRKRSPTESVNTPVGKDPGLAGRGDP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SLEQSYAHAGLGGMASIFGLLEIAQTHYYSKEPDKRKRSPTESVNTPVGKDPGLAGRGDP
             1030      1040      1050      1060      1070      1080

             1090      1100      1110      1120      1130      1140
pF1KA0 KAMAQLRVPQLGPRAPSATGKGPKELDTRSLKEENFIASIELWNKHQEVKKQKALEKQRP
       ::::::::::::::::::::::::::::::::::::::::                   :
XP_016 KAMAQLRVPQLGPRAPSATGKGPKELDTRSLKEENFIASIG------------------P
             1090      1100      1110      1120                    

             1150      1160      1170      1180      1190      1200
pF1KA0 EVIKPVFDLGETEEKKSQISADSGVSLTSSSQRTDQDSVIGVSPAVMIRSSSQDSEVSTV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EVIKPVFDLGETEEKKSQISADSGVSLTSSSQRTDQDSVIGVSPAVMIRSSSQDSEVSTV
           1130      1140      1150      1160      1170      1180  

             1210      1220      1230      1240      1250      1260
pF1KA0 VSNSSGETLGADSDLSSNAGDGPGGEGSVHLASSRGTLSDSEIETNSATSTIFGKAHSLK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VSNSSGETLGADSDLSSNAGDGPGGEGSVHLASSRGTLSDSEIETNSATSTIFGKAHSLK
           1190      1200      1210      1220      1230      1240  

             1270      1280      1290      1300      1310      1320
pF1KA0 PSIKEKLAGSPIRTSEDVSQRVYLYEGLLGRDKGSMWDQLEDAAMETFSISKERSTLWDQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PSIKEKLAGSPIRTSEDVSQRVYLYEGLLGRDKGSMWDQLEDAAMETFSISKERSTLWDQ
           1250      1260      1270      1280      1290      1300  

             1330      1340      1350      1360      1370      1380
pF1KA0 MQFWEDAFLDAVMLEREGMGMDQGPQEMIDRYLSLGEHDRKRLEDDEDRLLATLLHNLIS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MQFWEDAFLDAVMLEREGMGMDQGPQEMIDRYLSLGEHDRKRLEDDEDRLLATLLHNLIS
           1310      1320      1330      1340      1350      1360  

             1390      1400      1410      1420      1430      1440
pF1KA0 YMLLMKVNKNDIRKKVRRLMGKSHIGLVYSQQINEVLDQLANLNGRDLSIWSSGSRHMKK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 YMLLMKVNKNDIRKKVRRLMGKSHIGLVYSQQINEVLDQLANLNGRDLSIWSSGSRHMKK
           1370      1380      1390      1400      1410      1420  

             1450      1460      1470      1480      1490      1500
pF1KA0 QTFVVHAGTDTNGDIFFMEVCDDCVVLRSNIGTVYERWWYEKLINMTYCPKTKVLCLWRR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QTFVVHAGTDTNGDIFFMEVCDDCVVLRSNIGTVYERWWYEKLINMTYCPKTKVLCLWRR
           1430      1440      1450      1460      1470      1480  

             1510      1520      1530      1540      1550      1560
pF1KA0 NGSETQLNKFYTKKCRELYYCVKDSMERAAARQQSIKPGPELGGEFPVQDLKTGEGGLLQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NGSETQLNKFYTKKCRELYYCVKDSMERAAARQQSIKPGPELGGEFPVQDLKTGEGGLLQ
           1490      1500      1510      1520      1530      1540  

             1570      1580 
pF1KA0 VTLEGINLKFMHNQFLKLKKW
       :::::::::::::::::::::
XP_016 VTLEGINLKFMHNQFLKLKKW
           1550      1560   

>>XP_016873980 (OMIM: 603584) PREDICTED: MAP kinase-acti  (1562 aa)
 initn: 9958 init1: 7420 opt: 7475  Z-score: 6471.0  bits: 1210.2 E(85289):    0
Smith-Waterman score: 10269; 98.7% identity (98.7% similar) in 1581 aa overlap (1-1581:1-1562)

               10        20        30        40        50        60
pF1KA0 MVQKKKFCPRLLDYLVIVGARHPSSDSVAQTPELLRRYPLEDHTEFPLPPDVVFFCQPEG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MVQKKKFCPRLLDYLVIVGARHPSSDSVAQTPELLRRYPLEDHTEFPLPPDVVFFCQPEG
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KA0 CLSVRQRRMSLRDDTSFVFTLTDKDTGVTRYGICVNFYRSFQKRISKEKGEGGAGSRGKE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 CLSVRQRRMSLRDDTSFVFTLTDKDTGVTRYGICVNFYRSFQKRISKEKGEGGAGSRGKE
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KA0 GTHATCASEEGGTESSESGSSLQPLSADSTPDVNQSPRGKRRAKAGSRSRNSTLTSLCVL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GTHATCASEEGGTESSESGSSLQPLSADSTPDVNQSPRGKRRAKAGSRSRNSTLTSLCVL
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KA0 SHYPFFSTFRECLYTLKRLVDCCSERLLGKKLGIPRGVQRDTMWRIFTGSLLVEEKSSAL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SHYPFFSTFRECLYTLKRLVDCCSERLLGKKLGIPRGVQRDTMWRIFTGSLLVEEKSSAL
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KA0 LHDLREIEAWIYRLLRSPVPVSGQKRVDIEVLPQELQPALTFALPDPSRFTLVDFPLHLP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LHDLREIEAWIYRLLRSPVPVSGQKRVDIEVLPQELQPALTFALPDPSRFTLVDFPLHLP
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KA0 LELLGVDACLQVLTCILLEHKVVLQSRDYNALSMSVMAFVAMIYPLEYMFPVIPLLPTCM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LELLGVDACLQVLTCILLEHKVVLQSRDYNALSMSVMAFVAMIYPLEYMFPVIPLLPTCM
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KA0 ASAEQLLLAPTPYIIGVPASFFLYKLDFKMPDDVWLVDLDSNRVIAPTNAEVLPILPEPE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ASAEQLLLAPTPYIIGVPASFFLYKLDFKMPDDVWLVDLDSNRVIAPTNAEVLPILPEPE
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KA0 SLELKKHLKQALASMSLNTQPILNLEKFHEGQEIPLLLGRPSNDLQSTPSTEFNPLIYGN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SLELKKHLKQALASMSLNTQPILNLEKFHEGQEIPLLLGRPSNDLQSTPSTEFNPLIYGN
              430       440       450       460       470       480

              490       500       510       520       530       540
pF1KA0 DVDSVDVATRVAMVRFFNSANVLQGFQMHTRTLRLFPRPVVAFQAGSFLASRPRQTPFAE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DVDSVDVATRVAMVRFFNSANVLQGFQMHTRTLRLFPRPVVAFQAGSFLASRPRQTPFAE
              490       500       510       520       530       540

              550       560       570       580       590       600
pF1KA0 KLARTQAVEYFGEWILNPTNYAFQRIHNNMFDPALIGDKPKWYAHQLQPIHYRVYDSNSQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KLARTQAVEYFGEWILNPTNYAFQRIHNNMFDPALIGDKPKWYAHQLQPIHYRVYDSNSQ
              550       560       570       580       590       600

              610       620       630       640       650       660
pF1KA0 LAEALSVPPERDSDSEPTDDSGSDSMDYDDSSSSYSSLGDFVSEMMKCDINGDTPNVDPL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LAEALSVPPERDSDSEPTDDSGSDSMDYDDSSSSYSSLGDFVSEMMKCDINGDTPNVDPL
              610       620       630       640       650       660

              670       680       690       700       710       720
pF1KA0 THAALGDASEVEIDELQNQKEAEEPGPDSENSQENPPLRSSSSTTASSSPSTVIHGANSE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 THAALGDASEVEIDELQNQKEAEEPGPDSENSQENPPLRSSSSTTASSSPSTVIHGANSE
              670       680       690       700       710       720

              730       740       750       760       770       780
pF1KA0 PADSTEMDDKAAVGVSKPLPSVPPSIGKSNVDRRQAEIGEGSVRRRIYDNPYFEPQYGFP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PADSTEMDDKAAVGVSKPLPSVPPSIGKSNVDRRQAEIGEGSVRRRIYDNPYFEPQYGFP
              730       740       750       760       770       780

              790       800       810       820       830       840
pF1KA0 PEEDEDEQGESYTPRFSQHVSGNRAQKLLRPNSLRLASDSDAESDSRASSPNSTVSNTST
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PEEDEDEQGESYTPRFSQHVSGNRAQKLLRPNSLRLASDSDAESDSRASSPNSTVSNTST
              790       800       810       820       830       840

              850       860       870       880       890       900
pF1KA0 EGFGGIMSFASSLYRNHSTSFSLSNLTLPTKGAREKATPFPSLKVFGLNTLMEIVTEAGP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EGFGGIMSFASSLYRNHSTSFSLSNLTLPTKGAREKATPFPSLKVFGLNTLMEIVTEAGP
              850       860       870       880       890       900

              910       920       930       940       950       960
pF1KA0 GSGEGNRRALVDQKSSVIKHSPTVKREPPSPQGRSSNSSENQQFLKEVVHSVLDGQGVGW
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GSGEGNRRALVDQKSSVIKHSPTVKREPPSPQGRSSNSSENQQFLKEVVHSVLDGQGVGW
              910       920       930       940       950       960

              970       980       990      1000      1010      1020
pF1KA0 LNMKKVRRLLESEQLRVFVLSKLNRMVQSEDDARQDIIPDVEISRKVYKGMLDLLKCTVL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LNMKKVRRLLESEQLRVFVLSKLNRMVQSEDDARQDIIPDVEISRKVYKGMLDLLKCTVL
              970       980       990      1000      1010      1020

             1030      1040      1050      1060      1070      1080
pF1KA0 SLEQSYAHAGLGGMASIFGLLEIAQTHYYSKEPDKRKRSPTESVNTPVGKDPGLAGRGDP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SLEQSYAHAGLGGMASIFGLLEIAQTHYYSKEPDKRKRSPTESVNTPVGKDPGLAGRGDP
             1030      1040      1050      1060      1070      1080

             1090      1100      1110      1120      1130      1140
pF1KA0 KAMAQLRVPQLGPRAPSATGKGPKELDTRSLKEENFIASIELWNKHQEVKKQKALEKQRP
       ::::::::::::::::::::::::::::::::::::::::                   :
XP_016 KAMAQLRVPQLGPRAPSATGKGPKELDTRSLKEENFIASIG------------------P
             1090      1100      1110      1120                    

             1150      1160      1170      1180      1190      1200
pF1KA0 EVIKPVFDLGETEEKKSQISADSGVSLTSSSQRTDQDSVIGVSPAVMIRSSSQDSEVSTV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EVIKPVFDLGETEEKKSQISADSGVSLTSSSQRTDQDSVIGVSPAVMIRSSSQDSEVSTV
           1130      1140      1150      1160      1170      1180  

             1210      1220      1230      1240      1250      1260
pF1KA0 VSNSSGETLGADSDLSSNAGDGPGGEGSVHLASSRGTLSDSEIETNSATSTIFGKAHSLK
        :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 -SNSSGETLGADSDLSSNAGDGPGGEGSVHLASSRGTLSDSEIETNSATSTIFGKAHSLK
            1190      1200      1210      1220      1230      1240 

             1270      1280      1290      1300      1310      1320
pF1KA0 PSIKEKLAGSPIRTSEDVSQRVYLYEGLLGRDKGSMWDQLEDAAMETFSISKERSTLWDQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PSIKEKLAGSPIRTSEDVSQRVYLYEGLLGRDKGSMWDQLEDAAMETFSISKERSTLWDQ
            1250      1260      1270      1280      1290      1300 

             1330      1340      1350      1360      1370      1380
pF1KA0 MQFWEDAFLDAVMLEREGMGMDQGPQEMIDRYLSLGEHDRKRLEDDEDRLLATLLHNLIS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MQFWEDAFLDAVMLEREGMGMDQGPQEMIDRYLSLGEHDRKRLEDDEDRLLATLLHNLIS
            1310      1320      1330      1340      1350      1360 

             1390      1400      1410      1420      1430      1440
pF1KA0 YMLLMKVNKNDIRKKVRRLMGKSHIGLVYSQQINEVLDQLANLNGRDLSIWSSGSRHMKK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 YMLLMKVNKNDIRKKVRRLMGKSHIGLVYSQQINEVLDQLANLNGRDLSIWSSGSRHMKK
            1370      1380      1390      1400      1410      1420 

             1450      1460      1470      1480      1490      1500
pF1KA0 QTFVVHAGTDTNGDIFFMEVCDDCVVLRSNIGTVYERWWYEKLINMTYCPKTKVLCLWRR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QTFVVHAGTDTNGDIFFMEVCDDCVVLRSNIGTVYERWWYEKLINMTYCPKTKVLCLWRR
            1430      1440      1450      1460      1470      1480 

             1510      1520      1530      1540      1550      1560
pF1KA0 NGSETQLNKFYTKKCRELYYCVKDSMERAAARQQSIKPGPELGGEFPVQDLKTGEGGLLQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NGSETQLNKFYTKKCRELYYCVKDSMERAAARQQSIKPGPELGGEFPVQDLKTGEGGLLQ
            1490      1500      1510      1520      1530      1540 

             1570      1580 
pF1KA0 VTLEGINLKFMHNQFLKLKKW
       :::::::::::::::::::::
XP_016 VTLEGINLKFMHNQFLKLKKW
            1550      1560  

>>XP_016873981 (OMIM: 603584) PREDICTED: MAP kinase-acti  (1559 aa)
 initn: 9952 init1: 7420 opt: 7472  Z-score: 6468.4  bits: 1209.7 E(85289):    0
Smith-Waterman score: 10248; 98.5% identity (98.5% similar) in 1581 aa overlap (1-1581:1-1559)

               10        20        30        40        50        60
pF1KA0 MVQKKKFCPRLLDYLVIVGARHPSSDSVAQTPELLRRYPLEDHTEFPLPPDVVFFCQPEG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MVQKKKFCPRLLDYLVIVGARHPSSDSVAQTPELLRRYPLEDHTEFPLPPDVVFFCQPEG
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KA0 CLSVRQRRMSLRDDTSFVFTLTDKDTGVTRYGICVNFYRSFQKRISKEKGEGGAGSRGKE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 CLSVRQRRMSLRDDTSFVFTLTDKDTGVTRYGICVNFYRSFQKRISKEKGEGGAGSRGKE
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KA0 GTHATCASEEGGTESSESGSSLQPLSADSTPDVNQSPRGKRRAKAGSRSRNSTLTSLCVL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GTHATCASEEGGTESSESGSSLQPLSADSTPDVNQSPRGKRRAKAGSRSRNSTLTSLCVL
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KA0 SHYPFFSTFRECLYTLKRLVDCCSERLLGKKLGIPRGVQRDTMWRIFTGSLLVEEKSSAL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SHYPFFSTFRECLYTLKRLVDCCSERLLGKKLGIPRGVQRDTMWRIFTGSLLVEEKSSAL
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KA0 LHDLREIEAWIYRLLRSPVPVSGQKRVDIEVLPQELQPALTFALPDPSRFTLVDFPLHLP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LHDLREIEAWIYRLLRSPVPVSGQKRVDIEVLPQELQPALTFALPDPSRFTLVDFPLHLP
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KA0 LELLGVDACLQVLTCILLEHKVVLQSRDYNALSMSVMAFVAMIYPLEYMFPVIPLLPTCM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LELLGVDACLQVLTCILLEHKVVLQSRDYNALSMSVMAFVAMIYPLEYMFPVIPLLPTCM
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KA0 ASAEQLLLAPTPYIIGVPASFFLYKLDFKMPDDVWLVDLDSNRVIAPTNAEVLPILPEPE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ASAEQLLLAPTPYIIGVPASFFLYKLDFKMPDDVWLVDLDSNRVIAPTNAEVLPILPEPE
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KA0 SLELKKHLKQALASMSLNTQPILNLEKFHEGQEIPLLLGRPSNDLQSTPSTEFNPLIYGN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SLELKKHLKQALASMSLNTQPILNLEKFHEGQEIPLLLGRPSNDLQSTPSTEFNPLIYGN
              430       440       450       460       470       480

              490       500       510       520       530       540
pF1KA0 DVDSVDVATRVAMVRFFNSANVLQGFQMHTRTLRLFPRPVVAFQAGSFLASRPRQTPFAE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DVDSVDVATRVAMVRFFNSANVLQGFQMHTRTLRLFPRPVVAFQAGSFLASRPRQTPFAE
              490       500       510       520       530       540

              550       560       570       580       590       600
pF1KA0 KLARTQAVEYFGEWILNPTNYAFQRIHNNMFDPALIGDKPKWYAHQLQPIHYRVYDSNSQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KLARTQAVEYFGEWILNPTNYAFQRIHNNMFDPALIGDKPKWYAHQLQPIHYRVYDSNSQ
              550       560       570       580       590       600

              610       620       630       640       650       660
pF1KA0 LAEALSVPPERDSDSEPTDDSGSDSMDYDDSSSSYSSLGDFVSEMMKCDINGDTPNVDPL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LAEALSVPPERDSDSEPTDDSGSDSMDYDDSSSSYSSLGDFVSEMMKCDINGDTPNVDPL
              610       620       630       640       650       660

              670       680       690       700       710       720
pF1KA0 THAALGDASEVEIDELQNQKEAEEPGPDSENSQENPPLRSSSSTTASSSPSTVIHGANSE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 THAALGDASEVEIDELQNQKEAEEPGPDSENSQENPPLRSSSSTTASSSPSTVIHGANSE
              670       680       690       700       710       720

              730       740       750       760       770       780
pF1KA0 PADSTEMDDKAAVGVSKPLPSVPPSIGKSNVDRRQAEIGEGSVRRRIYDNPYFEPQYGFP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PADSTEMDDKAAVGVSKPLPSVPPSIGKSNVDRRQAEIGEGSVRRRIYDNPYFEPQYGFP
              730       740       750       760       770       780

              790       800       810       820       830       840
pF1KA0 PEEDEDEQGESYTPRFSQHVSGNRAQKLLRPNSLRLASDSDAESDSRASSPNSTVSNTST
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PEEDEDEQGESYTPRFSQHVSGNRAQKLLRPNSLRLASDSDAESDSRASSPNSTVSNTST
              790       800       810       820       830       840

              850       860       870       880       890       900
pF1KA0 EGFGGIMSFASSLYRNHSTSFSLSNLTLPTKGAREKATPFPSLKVFGLNTLMEIVTEAGP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EGFGGIMSFASSLYRNHSTSFSLSNLTLPTKGAREKATPFPSLKVFGLNTLMEIVTEAGP
              850       860       870       880       890       900

              910       920       930       940       950       960
pF1KA0 GSGEGNRRALVDQKSSVIKHSPTVKREPPSPQGRSSNSSENQQFLKEVVHSVLDGQGVGW
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GSGEGNRRALVDQKSSVIKHSPTVKREPPSPQGRSSNSSENQQFLKEVVHSVLDGQGVGW
              910       920       930       940       950       960

              970       980       990      1000      1010      1020
pF1KA0 LNMKKVRRLLESEQLRVFVLSKLNRMVQSEDDARQDIIPDVEISRKVYKGMLDLLKCTVL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LNMKKVRRLLESEQLRVFVLSKLNRMVQSEDDARQDIIPDVEISRKVYKGMLDLLKCTVL
              970       980       990      1000      1010      1020

             1030      1040      1050      1060      1070      1080
pF1KA0 SLEQSYAHAGLGGMASIFGLLEIAQTHYYSKEPDKRKRSPTESVNTPVGKDPGLAGRGDP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SLEQSYAHAGLGGMASIFGLLEIAQTHYYSKEPDKRKRSPTESVNTPVGKDPGLAGRGDP
             1030      1040      1050      1060      1070      1080

             1090      1100      1110      1120      1130      1140
pF1KA0 KAMAQLRVPQLGPRAPSATGKGPKELDTRSLKEENFIASIELWNKHQEVKKQKALEKQRP
       ::::::::::::::::::::::::::::::::::::::::                   :
XP_016 KAMAQLRVPQLGPRAPSATGKGPKELDTRSLKEENFIASIG------------------P
             1090      1100      1110      1120                    

             1150      1160      1170      1180      1190      1200
pF1KA0 EVIKPVFDLGETEEKKSQISADSGVSLTSSSQRTDQDSVIGVSPAVMIRSSSQDSEVSTV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::  
XP_016 EVIKPVFDLGETEEKKSQISADSGVSLTSSSQRTDQDSVIGVSPAVMIRSSSQDSEVS--
           1130      1140      1150      1160      1170      1180  

             1210      1220      1230      1240      1250      1260
pF1KA0 VSNSSGETLGADSDLSSNAGDGPGGEGSVHLASSRGTLSDSEIETNSATSTIFGKAHSLK
         ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 --NSSGETLGADSDLSSNAGDGPGGEGSVHLASSRGTLSDSEIETNSATSTIFGKAHSLK
               1190      1200      1210      1220      1230        

             1270      1280      1290      1300      1310      1320
pF1KA0 PSIKEKLAGSPIRTSEDVSQRVYLYEGLLGRDKGSMWDQLEDAAMETFSISKERSTLWDQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PSIKEKLAGSPIRTSEDVSQRVYLYEGLLGRDKGSMWDQLEDAAMETFSISKERSTLWDQ
     1240      1250      1260      1270      1280      1290        

             1330      1340      1350      1360      1370      1380
pF1KA0 MQFWEDAFLDAVMLEREGMGMDQGPQEMIDRYLSLGEHDRKRLEDDEDRLLATLLHNLIS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MQFWEDAFLDAVMLEREGMGMDQGPQEMIDRYLSLGEHDRKRLEDDEDRLLATLLHNLIS
     1300      1310      1320      1330      1340      1350        

             1390      1400      1410      1420      1430      1440
pF1KA0 YMLLMKVNKNDIRKKVRRLMGKSHIGLVYSQQINEVLDQLANLNGRDLSIWSSGSRHMKK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 YMLLMKVNKNDIRKKVRRLMGKSHIGLVYSQQINEVLDQLANLNGRDLSIWSSGSRHMKK
     1360      1370      1380      1390      1400      1410        

             1450      1460      1470      1480      1490      1500
pF1KA0 QTFVVHAGTDTNGDIFFMEVCDDCVVLRSNIGTVYERWWYEKLINMTYCPKTKVLCLWRR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QTFVVHAGTDTNGDIFFMEVCDDCVVLRSNIGTVYERWWYEKLINMTYCPKTKVLCLWRR
     1420      1430      1440      1450      1460      1470        

             1510      1520      1530      1540      1550      1560
pF1KA0 NGSETQLNKFYTKKCRELYYCVKDSMERAAARQQSIKPGPELGGEFPVQDLKTGEGGLLQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NGSETQLNKFYTKKCRELYYCVKDSMERAAARQQSIKPGPELGGEFPVQDLKTGEGGLLQ
     1480      1490      1500      1510      1520      1530        

             1570      1580 
pF1KA0 VTLEGINLKFMHNQFLKLKKW
       :::::::::::::::::::::
XP_016 VTLEGINLKFMHNQFLKLKKW
     1540      1550         




1581 residues in 1 query   sequences
60827320 residues in 85289 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Wed Nov  2 18:42:34 2016 done: Wed Nov  2 18:42:36 2016
 Total Scan time: 13.330 Total Display time:  1.180

Function used was FASTA [36.3.4 Apr, 2011]
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