Result of FASTA (omim) for pF1KA0090
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KA0090, 992 aa
  1>>>pF1KA0090 992 - 992 aa - 992 aa
Library: /omim/omim.rfq.tfa
  60827320 residues in 85289 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 6.1849+/-0.000469; mu= 16.3963+/- 0.029
 mean_var=71.7888+/-14.457, 0's: 0 Z-trim(109.0): 30  B-trim: 0 in 0/50
 Lambda= 0.151372
 statistics sampled from 17166 (17174) to 17166 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.538), E-opt: 0.2 (0.201), width:  16
 Scan time: 11.340

The best scores are:                                      opt bits E(85289)
NP_001258356 (OMIM: 616846,616875) ER membrane pro ( 992) 6507 1431.2       0
NP_055862 (OMIM: 616846,616875) ER membrane protei ( 993) 6495 1428.6       0
XP_005245845 (OMIM: 616846,616875) PREDICTED: ER m ( 995) 6491 1427.7       0
XP_005245844 (OMIM: 616846,616875) PREDICTED: ER m ( 996) 6479 1425.1       0
NP_001258357 (OMIM: 616846,616875) ER membrane pro ( 992) 6478 1424.8       0
NP_001258358 (OMIM: 616846,616875) ER membrane pro ( 971) 5854 1288.6       0


>>NP_001258356 (OMIM: 616846,616875) ER membrane protein  (992 aa)
 initn: 6507 init1: 6507 opt: 6507  Z-score: 7672.6  bits: 1431.2 E(85289):    0
Smith-Waterman score: 6507; 100.0% identity (100.0% similar) in 992 aa overlap (1-992:1-992)

               10        20        30        40        50        60
pF1KA0 MAAEWASRFWLWATLLIPAAAVYEDQVGKFDWRQQYVGKVKFASLEFSPGSKKLVVATEK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MAAEWASRFWLWATLLIPAAAVYEDQVGKFDWRQQYVGKVKFASLEFSPGSKKLVVATEK
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KA0 NVIAALNSRTGEILWRHVDKGTAEGAVDAMLLHGQDVITVSNGGRIMRSWETNIGGLNWE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NVIAALNSRTGEILWRHVDKGTAEGAVDAMLLHGQDVITVSNGGRIMRSWETNIGGLNWE
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KA0 ITLDSGSFQALGLVGLQESVRYIAVLKKTTLALHHLSSGHLKWVEHLPESDSIHYQMVYS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ITLDSGSFQALGLVGLQESVRYIAVLKKTTLALHHLSSGHLKWVEHLPESDSIHYQMVYS
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KA0 YGSGVVWALGVVPFSHVNIVKFNVEDGEIVQQVRVSTPWLQHLSGACGVVDEAVLVCPDP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 YGSGVVWALGVVPFSHVNIVKFNVEDGEIVQQVRVSTPWLQHLSGACGVVDEAVLVCPDP
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KA0 SSRSLQTLALETEWELRQIPLQSLDLEFGSGFQPRVLPTQPNPVDASRAQFFLHLSPSHY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SSRSLQTLALETEWELRQIPLQSLDLEFGSGFQPRVLPTQPNPVDASRAQFFLHLSPSHY
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KA0 ALLQYHYGTLSLLKNFPQTALVSFATTGEKTVAAVMACRNEVKSSSSEDGSMGSFSEKSS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ALLQYHYGTLSLLKNFPQTALVSFATTGEKTVAAVMACRNEVKSSSSEDGSMGSFSEKSS
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KA0 SKDSLACFNQTYTINLYLVETGRRLLDTTITFSLEQSGTRPERLYIQVFLKKDDSVGYRA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SKDSLACFNQTYTINLYLVETGRRLLDTTITFSLEQSGTRPERLYIQVFLKKDDSVGYRA
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KA0 LVQTEDHLLLFLQQLAGKVVLWSREESLAEVVCLEMVDLPLTGAQAELEGEFGKKADGLL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LVQTEDHLLLFLQQLAGKVVLWSREESLAEVVCLEMVDLPLTGAQAELEGEFGKKADGLL
              430       440       450       460       470       480

              490       500       510       520       530       540
pF1KA0 GMFLKRLSSQLILLQAWTSHLWKMFYDARKPRSQIKNEINIDTLARDEFNLQKMMVMVTA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GMFLKRLSSQLILLQAWTSHLWKMFYDARKPRSQIKNEINIDTLARDEFNLQKMMVMVTA
              490       500       510       520       530       540

              550       560       570       580       590       600
pF1KA0 SGKLFGIESSSGTILWKQYLPNVKPDSSFKLMVQRTTAHFPHPPQCTLLVKDKESGMSSL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SGKLFGIESSSGTILWKQYLPNVKPDSSFKLMVQRTTAHFPHPPQCTLLVKDKESGMSSL
              550       560       570       580       590       600

              610       620       630       640       650       660
pF1KA0 YVFNPIFGKWSQVAPPVLKRPILQSLLLPVMDQDYAKVLLLIDDEYKVTAFPATRNVLRQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 YVFNPIFGKWSQVAPPVLKRPILQSLLLPVMDQDYAKVLLLIDDEYKVTAFPATRNVLRQ
              610       620       630       640       650       660

              670       680       690       700       710       720
pF1KA0 LHELAPSIFFYLVDAEQGRLCGYRLRKDLTTELSWELTIPPEVQRIVKVKGKRSSEHVHS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LHELAPSIFFYLVDAEQGRLCGYRLRKDLTTELSWELTIPPEVQRIVKVKGKRSSEHVHS
              670       680       690       700       710       720

              730       740       750       760       770       780
pF1KA0 QGRVMGDRSVLYKSLNPNLLAVVTESTDAHHERTFIGIFLIDGVTGRIIHSSVQKKAKGP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QGRVMGDRSVLYKSLNPNLLAVVTESTDAHHERTFIGIFLIDGVTGRIIHSSVQKKAKGP
              730       740       750       760       770       780

              790       800       810       820       830       840
pF1KA0 VHIVHSENWVVYQYWNTKARRNEFTVLELYEGTEQYNATAFSSLDRPQLPQVLQQSYIFP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VHIVHSENWVVYQYWNTKARRNEFTVLELYEGTEQYNATAFSSLDRPQLPQVLQQSYIFP
              790       800       810       820       830       840

              850       860       870       880       890       900
pF1KA0 SSISAMEATITERGITSRHLLIGLPSGAILSLPKALLDPRRPEIPTEQSREENLIPYSPD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SSISAMEATITERGITSRHLLIGLPSGAILSLPKALLDPRRPEIPTEQSREENLIPYSPD
              850       860       870       880       890       900

              910       920       930       940       950       960
pF1KA0 VQIHAERFINYNQTVSRMRGIYTAPSGLESTCLVVAYGLDIYQTRVYPSKQFDVLKDDYD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VQIHAERFINYNQTVSRMRGIYTAPSGLESTCLVVAYGLDIYQTRVYPSKQFDVLKDDYD
              910       920       930       940       950       960

              970       980       990  
pF1KA0 YVLISSVLFGLVFATMITKRLAQVKLLNRAWR
       ::::::::::::::::::::::::::::::::
NP_001 YVLISSVLFGLVFATMITKRLAQVKLLNRAWR
              970       980       990  

>>NP_055862 (OMIM: 616846,616875) ER membrane protein co  (993 aa)
 initn: 4231 init1: 4231 opt: 6495  Z-score: 7658.5  bits: 1428.6 E(85289):    0
Smith-Waterman score: 6495; 99.9% identity (99.9% similar) in 993 aa overlap (1-992:1-993)

               10        20        30        40        50        60
pF1KA0 MAAEWASRFWLWATLLIPAAAVYEDQVGKFDWRQQYVGKVKFASLEFSPGSKKLVVATEK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 MAAEWASRFWLWATLLIPAAAVYEDQVGKFDWRQQYVGKVKFASLEFSPGSKKLVVATEK
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KA0 NVIAALNSRTGEILWRHVDKGTAEGAVDAMLLHGQDVITVSNGGRIMRSWETNIGGLNWE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 NVIAALNSRTGEILWRHVDKGTAEGAVDAMLLHGQDVITVSNGGRIMRSWETNIGGLNWE
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KA0 ITLDSGSFQALGLVGLQESVRYIAVLKKTTLALHHLSSGHLKWVEHLPESDSIHYQMVYS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 ITLDSGSFQALGLVGLQESVRYIAVLKKTTLALHHLSSGHLKWVEHLPESDSIHYQMVYS
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KA0 YGSGVVWALGVVPFSHVNIVKFNVEDGEIVQQVRVSTPWLQHLSGACGVVDEAVLVCPDP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 YGSGVVWALGVVPFSHVNIVKFNVEDGEIVQQVRVSTPWLQHLSGACGVVDEAVLVCPDP
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KA0 SSRSLQTLALETEWELRQIPLQSLDLEFGSGFQPRVLPTQPNPVDASRAQFFLHLSPSHY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 SSRSLQTLALETEWELRQIPLQSLDLEFGSGFQPRVLPTQPNPVDASRAQFFLHLSPSHY
              250       260       270       280       290       300

              310       320       330       340        350         
pF1KA0 ALLQYHYGTLSLLKNFPQTALVSFATTGEKTVAAVMACRNEV-KSSSSEDGSMGSFSEKS
       :::::::::::::::::::::::::::::::::::::::::: :::::::::::::::::
NP_055 ALLQYHYGTLSLLKNFPQTALVSFATTGEKTVAAVMACRNEVQKSSSSEDGSMGSFSEKS
              310       320       330       340       350       360

     360       370       380       390       400       410         
pF1KA0 SSKDSLACFNQTYTINLYLVETGRRLLDTTITFSLEQSGTRPERLYIQVFLKKDDSVGYR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 SSKDSLACFNQTYTINLYLVETGRRLLDTTITFSLEQSGTRPERLYIQVFLKKDDSVGYR
              370       380       390       400       410       420

     420       430       440       450       460       470         
pF1KA0 ALVQTEDHLLLFLQQLAGKVVLWSREESLAEVVCLEMVDLPLTGAQAELEGEFGKKADGL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 ALVQTEDHLLLFLQQLAGKVVLWSREESLAEVVCLEMVDLPLTGAQAELEGEFGKKADGL
              430       440       450       460       470       480

     480       490       500       510       520       530         
pF1KA0 LGMFLKRLSSQLILLQAWTSHLWKMFYDARKPRSQIKNEINIDTLARDEFNLQKMMVMVT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 LGMFLKRLSSQLILLQAWTSHLWKMFYDARKPRSQIKNEINIDTLARDEFNLQKMMVMVT
              490       500       510       520       530       540

     540       550       560       570       580       590         
pF1KA0 ASGKLFGIESSSGTILWKQYLPNVKPDSSFKLMVQRTTAHFPHPPQCTLLVKDKESGMSS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 ASGKLFGIESSSGTILWKQYLPNVKPDSSFKLMVQRTTAHFPHPPQCTLLVKDKESGMSS
              550       560       570       580       590       600

     600       610       620       630       640       650         
pF1KA0 LYVFNPIFGKWSQVAPPVLKRPILQSLLLPVMDQDYAKVLLLIDDEYKVTAFPATRNVLR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 LYVFNPIFGKWSQVAPPVLKRPILQSLLLPVMDQDYAKVLLLIDDEYKVTAFPATRNVLR
              610       620       630       640       650       660

     660       670       680       690       700       710         
pF1KA0 QLHELAPSIFFYLVDAEQGRLCGYRLRKDLTTELSWELTIPPEVQRIVKVKGKRSSEHVH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 QLHELAPSIFFYLVDAEQGRLCGYRLRKDLTTELSWELTIPPEVQRIVKVKGKRSSEHVH
              670       680       690       700       710       720

     720       730       740       750       760       770         
pF1KA0 SQGRVMGDRSVLYKSLNPNLLAVVTESTDAHHERTFIGIFLIDGVTGRIIHSSVQKKAKG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 SQGRVMGDRSVLYKSLNPNLLAVVTESTDAHHERTFIGIFLIDGVTGRIIHSSVQKKAKG
              730       740       750       760       770       780

     780       790       800       810       820       830         
pF1KA0 PVHIVHSENWVVYQYWNTKARRNEFTVLELYEGTEQYNATAFSSLDRPQLPQVLQQSYIF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 PVHIVHSENWVVYQYWNTKARRNEFTVLELYEGTEQYNATAFSSLDRPQLPQVLQQSYIF
              790       800       810       820       830       840

     840       850       860       870       880       890         
pF1KA0 PSSISAMEATITERGITSRHLLIGLPSGAILSLPKALLDPRRPEIPTEQSREENLIPYSP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 PSSISAMEATITERGITSRHLLIGLPSGAILSLPKALLDPRRPEIPTEQSREENLIPYSP
              850       860       870       880       890       900

     900       910       920       930       940       950         
pF1KA0 DVQIHAERFINYNQTVSRMRGIYTAPSGLESTCLVVAYGLDIYQTRVYPSKQFDVLKDDY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 DVQIHAERFINYNQTVSRMRGIYTAPSGLESTCLVVAYGLDIYQTRVYPSKQFDVLKDDY
              910       920       930       940       950       960

     960       970       980       990  
pF1KA0 DYVLISSVLFGLVFATMITKRLAQVKLLNRAWR
       :::::::::::::::::::::::::::::::::
NP_055 DYVLISSVLFGLVFATMITKRLAQVKLLNRAWR
              970       980       990   

>>XP_005245845 (OMIM: 616846,616875) PREDICTED: ER membr  (995 aa)
 initn: 6493 init1: 3387 opt: 6491  Z-score: 7653.7  bits: 1427.7 E(85289):    0
Smith-Waterman score: 6491; 99.7% identity (99.7% similar) in 995 aa overlap (1-992:1-995)

               10        20        30        40        50        60
pF1KA0 MAAEWASRFWLWATLLIPAAAVYEDQVGKFDWRQQYVGKVKFASLEFSPGSKKLVVATEK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MAAEWASRFWLWATLLIPAAAVYEDQVGKFDWRQQYVGKVKFASLEFSPGSKKLVVATEK
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KA0 NVIAALNSRTGEILWRHVDKGTAEGAVDAMLLHGQDVITVSNGGRIMRSWETNIGGLNWE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 NVIAALNSRTGEILWRHVDKGTAEGAVDAMLLHGQDVITVSNGGRIMRSWETNIGGLNWE
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KA0 ITLDSGSFQALGLVGLQESVRYIAVLKKTTLALHHLSSGHLKWVEHLPESDSIHYQMVYS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 ITLDSGSFQALGLVGLQESVRYIAVLKKTTLALHHLSSGHLKWVEHLPESDSIHYQMVYS
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KA0 YGSGVVWALGVVPFSHVNIVKFNVEDGEIVQQVRVSTPWLQHLSGACGVVDEAVLVCPDP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 YGSGVVWALGVVPFSHVNIVKFNVEDGEIVQQVRVSTPWLQHLSGACGVVDEAVLVCPDP
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KA0 SSRSLQTLALETEWELRQIPLQSLDLEFGSGFQPRVLPTQPNPVDASRAQFFLHLSPSHY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SSRSLQTLALETEWELRQIPLQSLDLEFGSGFQPRVLPTQPNPVDASRAQFFLHLSPSHY
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KA0 ALLQYHYGTLSLLKNFPQTALVSFATTGEKTVAAVMACRNEVKSSSSEDGSMGSFSEKSS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 ALLQYHYGTLSLLKNFPQTALVSFATTGEKTVAAVMACRNEVKSSSSEDGSMGSFSEKSS
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KA0 SKDSLACFNQTYTINLYLVETGRRLLDTTITFSLEQSGTRPERLYIQVFLKKDDSVGYRA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SKDSLACFNQTYTINLYLVETGRRLLDTTITFSLEQSGTRPERLYIQVFLKKDDSVGYRA
              370       380       390       400       410       420

              430       440       450       460       470          
pF1KA0 LVQTEDHLLLFLQQLAGKVVLWSREESLAEVVCLEMVDLPLTGAQAELEGEFGKKA---D
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::   :
XP_005 LVQTEDHLLLFLQQLAGKVVLWSREESLAEVVCLEMVDLPLTGAQAELEGEFGKKAAIQD
              430       440       450       460       470       480

       480       490       500       510       520       530       
pF1KA0 GLLGMFLKRLSSQLILLQAWTSHLWKMFYDARKPRSQIKNEINIDTLARDEFNLQKMMVM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 GLLGMFLKRLSSQLILLQAWTSHLWKMFYDARKPRSQIKNEINIDTLARDEFNLQKMMVM
              490       500       510       520       530       540

       540       550       560       570       580       590       
pF1KA0 VTASGKLFGIESSSGTILWKQYLPNVKPDSSFKLMVQRTTAHFPHPPQCTLLVKDKESGM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 VTASGKLFGIESSSGTILWKQYLPNVKPDSSFKLMVQRTTAHFPHPPQCTLLVKDKESGM
              550       560       570       580       590       600

       600       610       620       630       640       650       
pF1KA0 SSLYVFNPIFGKWSQVAPPVLKRPILQSLLLPVMDQDYAKVLLLIDDEYKVTAFPATRNV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SSLYVFNPIFGKWSQVAPPVLKRPILQSLLLPVMDQDYAKVLLLIDDEYKVTAFPATRNV
              610       620       630       640       650       660

       660       670       680       690       700       710       
pF1KA0 LRQLHELAPSIFFYLVDAEQGRLCGYRLRKDLTTELSWELTIPPEVQRIVKVKGKRSSEH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LRQLHELAPSIFFYLVDAEQGRLCGYRLRKDLTTELSWELTIPPEVQRIVKVKGKRSSEH
              670       680       690       700       710       720

       720       730       740       750       760       770       
pF1KA0 VHSQGRVMGDRSVLYKSLNPNLLAVVTESTDAHHERTFIGIFLIDGVTGRIIHSSVQKKA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 VHSQGRVMGDRSVLYKSLNPNLLAVVTESTDAHHERTFIGIFLIDGVTGRIIHSSVQKKA
              730       740       750       760       770       780

       780       790       800       810       820       830       
pF1KA0 KGPVHIVHSENWVVYQYWNTKARRNEFTVLELYEGTEQYNATAFSSLDRPQLPQVLQQSY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 KGPVHIVHSENWVVYQYWNTKARRNEFTVLELYEGTEQYNATAFSSLDRPQLPQVLQQSY
              790       800       810       820       830       840

       840       850       860       870       880       890       
pF1KA0 IFPSSISAMEATITERGITSRHLLIGLPSGAILSLPKALLDPRRPEIPTEQSREENLIPY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 IFPSSISAMEATITERGITSRHLLIGLPSGAILSLPKALLDPRRPEIPTEQSREENLIPY
              850       860       870       880       890       900

       900       910       920       930       940       950       
pF1KA0 SPDVQIHAERFINYNQTVSRMRGIYTAPSGLESTCLVVAYGLDIYQTRVYPSKQFDVLKD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SPDVQIHAERFINYNQTVSRMRGIYTAPSGLESTCLVVAYGLDIYQTRVYPSKQFDVLKD
              910       920       930       940       950       960

       960       970       980       990  
pF1KA0 DYDYVLISSVLFGLVFATMITKRLAQVKLLNRAWR
       :::::::::::::::::::::::::::::::::::
XP_005 DYDYVLISSVLFGLVFATMITKRLAQVKLLNRAWR
              970       980       990     

>>XP_005245844 (OMIM: 616846,616875) PREDICTED: ER membr  (996 aa)
 initn: 5667 init1: 3387 opt: 6479  Z-score: 7639.5  bits: 1425.1 E(85289):    0
Smith-Waterman score: 6479; 99.6% identity (99.6% similar) in 996 aa overlap (1-992:1-996)

               10        20        30        40        50        60
pF1KA0 MAAEWASRFWLWATLLIPAAAVYEDQVGKFDWRQQYVGKVKFASLEFSPGSKKLVVATEK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MAAEWASRFWLWATLLIPAAAVYEDQVGKFDWRQQYVGKVKFASLEFSPGSKKLVVATEK
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KA0 NVIAALNSRTGEILWRHVDKGTAEGAVDAMLLHGQDVITVSNGGRIMRSWETNIGGLNWE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 NVIAALNSRTGEILWRHVDKGTAEGAVDAMLLHGQDVITVSNGGRIMRSWETNIGGLNWE
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KA0 ITLDSGSFQALGLVGLQESVRYIAVLKKTTLALHHLSSGHLKWVEHLPESDSIHYQMVYS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 ITLDSGSFQALGLVGLQESVRYIAVLKKTTLALHHLSSGHLKWVEHLPESDSIHYQMVYS
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KA0 YGSGVVWALGVVPFSHVNIVKFNVEDGEIVQQVRVSTPWLQHLSGACGVVDEAVLVCPDP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 YGSGVVWALGVVPFSHVNIVKFNVEDGEIVQQVRVSTPWLQHLSGACGVVDEAVLVCPDP
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KA0 SSRSLQTLALETEWELRQIPLQSLDLEFGSGFQPRVLPTQPNPVDASRAQFFLHLSPSHY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SSRSLQTLALETEWELRQIPLQSLDLEFGSGFQPRVLPTQPNPVDASRAQFFLHLSPSHY
              250       260       270       280       290       300

              310       320       330       340        350         
pF1KA0 ALLQYHYGTLSLLKNFPQTALVSFATTGEKTVAAVMACRNEV-KSSSSEDGSMGSFSEKS
       :::::::::::::::::::::::::::::::::::::::::: :::::::::::::::::
XP_005 ALLQYHYGTLSLLKNFPQTALVSFATTGEKTVAAVMACRNEVQKSSSSEDGSMGSFSEKS
              310       320       330       340       350       360

     360       370       380       390       400       410         
pF1KA0 SSKDSLACFNQTYTINLYLVETGRRLLDTTITFSLEQSGTRPERLYIQVFLKKDDSVGYR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SSKDSLACFNQTYTINLYLVETGRRLLDTTITFSLEQSGTRPERLYIQVFLKKDDSVGYR
              370       380       390       400       410       420

     420       430       440       450       460       470         
pF1KA0 ALVQTEDHLLLFLQQLAGKVVLWSREESLAEVVCLEMVDLPLTGAQAELEGEFGKKA---
       :::::::::::::::::::::::::::::::::::::::::::::::::::::::::   
XP_005 ALVQTEDHLLLFLQQLAGKVVLWSREESLAEVVCLEMVDLPLTGAQAELEGEFGKKAAIQ
              430       440       450       460       470       480

        480       490       500       510       520       530      
pF1KA0 DGLLGMFLKRLSSQLILLQAWTSHLWKMFYDARKPRSQIKNEINIDTLARDEFNLQKMMV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 DGLLGMFLKRLSSQLILLQAWTSHLWKMFYDARKPRSQIKNEINIDTLARDEFNLQKMMV
              490       500       510       520       530       540

        540       550       560       570       580       590      
pF1KA0 MVTASGKLFGIESSSGTILWKQYLPNVKPDSSFKLMVQRTTAHFPHPPQCTLLVKDKESG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MVTASGKLFGIESSSGTILWKQYLPNVKPDSSFKLMVQRTTAHFPHPPQCTLLVKDKESG
              550       560       570       580       590       600

        600       610       620       630       640       650      
pF1KA0 MSSLYVFNPIFGKWSQVAPPVLKRPILQSLLLPVMDQDYAKVLLLIDDEYKVTAFPATRN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MSSLYVFNPIFGKWSQVAPPVLKRPILQSLLLPVMDQDYAKVLLLIDDEYKVTAFPATRN
              610       620       630       640       650       660

        660       670       680       690       700       710      
pF1KA0 VLRQLHELAPSIFFYLVDAEQGRLCGYRLRKDLTTELSWELTIPPEVQRIVKVKGKRSSE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 VLRQLHELAPSIFFYLVDAEQGRLCGYRLRKDLTTELSWELTIPPEVQRIVKVKGKRSSE
              670       680       690       700       710       720

        720       730       740       750       760       770      
pF1KA0 HVHSQGRVMGDRSVLYKSLNPNLLAVVTESTDAHHERTFIGIFLIDGVTGRIIHSSVQKK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 HVHSQGRVMGDRSVLYKSLNPNLLAVVTESTDAHHERTFIGIFLIDGVTGRIIHSSVQKK
              730       740       750       760       770       780

        780       790       800       810       820       830      
pF1KA0 AKGPVHIVHSENWVVYQYWNTKARRNEFTVLELYEGTEQYNATAFSSLDRPQLPQVLQQS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 AKGPVHIVHSENWVVYQYWNTKARRNEFTVLELYEGTEQYNATAFSSLDRPQLPQVLQQS
              790       800       810       820       830       840

        840       850       860       870       880       890      
pF1KA0 YIFPSSISAMEATITERGITSRHLLIGLPSGAILSLPKALLDPRRPEIPTEQSREENLIP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 YIFPSSISAMEATITERGITSRHLLIGLPSGAILSLPKALLDPRRPEIPTEQSREENLIP
              850       860       870       880       890       900

        900       910       920       930       940       950      
pF1KA0 YSPDVQIHAERFINYNQTVSRMRGIYTAPSGLESTCLVVAYGLDIYQTRVYPSKQFDVLK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 YSPDVQIHAERFINYNQTVSRMRGIYTAPSGLESTCLVVAYGLDIYQTRVYPSKQFDVLK
              910       920       930       940       950       960

        960       970       980       990  
pF1KA0 DDYDYVLISSVLFGLVFATMITKRLAQVKLLNRAWR
       ::::::::::::::::::::::::::::::::::::
XP_005 DDYDYVLISSVLFGLVFATMITKRLAQVKLLNRAWR
              970       980       990      

>>NP_001258357 (OMIM: 616846,616875) ER membrane protein  (992 aa)
 initn: 5883 init1: 5883 opt: 6478  Z-score: 7638.4  bits: 1424.8 E(85289):    0
Smith-Waterman score: 6478; 99.8% identity (99.8% similar) in 993 aa overlap (1-992:1-992)

               10        20        30        40        50        60
pF1KA0 MAAEWASRFWLWATLLIPAAAVYEDQVGKFDWRQQYVGKVKFASLEFSPGSKKLVVATEK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MAAEWASRFWLWATLLIPAAAVYEDQVGKFDWRQQYVGKVKFASLEFSPGSKKLVVATEK
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KA0 NVIAALNSRTGEILWRHVDKGTAEGAVDAMLLHGQDVITVSNGGRIMRSWETNIGGLNWE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NVIAALNSRTGEILWRHVDKGTAEGAVDAMLLHGQDVITVSNGGRIMRSWETNIGGLNWE
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KA0 ITLDSGSFQALGLVGLQESVRYIAVLKKTTLALHHLSSGHLKWVEHLPESDSIHYQMVYS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ITLDSGSFQALGLVGLQESVRYIAVLKKTTLALHHLSSGHLKWVEHLPESDSIHYQMVYS
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KA0 YGSGVVWALGVVPFSHVNIVKFNVEDGEIVQQVRVSTPWLQHLSGACGVVDEAVLVCPDP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 YGSGVVWALGVVPFSHVNIVKFNVEDGEIVQQVRVSTPWLQHLSGACGVVDEAVLVCPDP
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KA0 SSRSLQTLALETEWELRQIPLQSLDLEFGSGFQPRVLPTQPNPVDASRAQFFLHLSPSHY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SSRSLQTLALETEWELRQIPLQSLDLEFGSGFQPRVLPTQPNPVDASRAQFFLHLSPSHY
              250       260       270       280       290       300

              310       320       330       340        350         
pF1KA0 ALLQYHYGTLSLLKNFPQTALVSFATTGEKTVAAVMACRNEV-KSSSSEDGSMGSFSEKS
       :::::::::::::::::::::::::::::::::::::::::: :::::::::::::::::
NP_001 ALLQYHYGTLSLLKNFPQTALVSFATTGEKTVAAVMACRNEVQKSSSSEDGSMGSFSEKS
              310       320       330       340       350       360

     360       370       380       390       400       410         
pF1KA0 SSKDSLACFNQTYTINLYLVETGRRLLDTTITFSLEQSGTRPERLYIQVFLKKDDSVGYR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SSKDSLACFNQTYTINLYLVETGRRLLDTTITFSLEQSGTRPERLYIQVFLKKDDSVGYR
              370       380       390       400       410       420

     420       430       440       450       460       470         
pF1KA0 ALVQTEDHLLLFLQQLAGKVVLWSREESLAEVVCLEMVDLPLTGAQAELEGEFGKKADGL
       :::::::::::::::: :::::::::::::::::::::::::::::::::::::::::::
NP_001 ALVQTEDHLLLFLQQL-GKVVLWSREESLAEVVCLEMVDLPLTGAQAELEGEFGKKADGL
              430        440       450       460       470         

     480       490       500       510       520       530         
pF1KA0 LGMFLKRLSSQLILLQAWTSHLWKMFYDARKPRSQIKNEINIDTLARDEFNLQKMMVMVT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LGMFLKRLSSQLILLQAWTSHLWKMFYDARKPRSQIKNEINIDTLARDEFNLQKMMVMVT
     480       490       500       510       520       530         

     540       550       560       570       580       590         
pF1KA0 ASGKLFGIESSSGTILWKQYLPNVKPDSSFKLMVQRTTAHFPHPPQCTLLVKDKESGMSS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ASGKLFGIESSSGTILWKQYLPNVKPDSSFKLMVQRTTAHFPHPPQCTLLVKDKESGMSS
     540       550       560       570       580       590         

     600       610       620       630       640       650         
pF1KA0 LYVFNPIFGKWSQVAPPVLKRPILQSLLLPVMDQDYAKVLLLIDDEYKVTAFPATRNVLR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LYVFNPIFGKWSQVAPPVLKRPILQSLLLPVMDQDYAKVLLLIDDEYKVTAFPATRNVLR
     600       610       620       630       640       650         

     660       670       680       690       700       710         
pF1KA0 QLHELAPSIFFYLVDAEQGRLCGYRLRKDLTTELSWELTIPPEVQRIVKVKGKRSSEHVH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QLHELAPSIFFYLVDAEQGRLCGYRLRKDLTTELSWELTIPPEVQRIVKVKGKRSSEHVH
     660       670       680       690       700       710         

     720       730       740       750       760       770         
pF1KA0 SQGRVMGDRSVLYKSLNPNLLAVVTESTDAHHERTFIGIFLIDGVTGRIIHSSVQKKAKG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SQGRVMGDRSVLYKSLNPNLLAVVTESTDAHHERTFIGIFLIDGVTGRIIHSSVQKKAKG
     720       730       740       750       760       770         

     780       790       800       810       820       830         
pF1KA0 PVHIVHSENWVVYQYWNTKARRNEFTVLELYEGTEQYNATAFSSLDRPQLPQVLQQSYIF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PVHIVHSENWVVYQYWNTKARRNEFTVLELYEGTEQYNATAFSSLDRPQLPQVLQQSYIF
     780       790       800       810       820       830         

     840       850       860       870       880       890         
pF1KA0 PSSISAMEATITERGITSRHLLIGLPSGAILSLPKALLDPRRPEIPTEQSREENLIPYSP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PSSISAMEATITERGITSRHLLIGLPSGAILSLPKALLDPRRPEIPTEQSREENLIPYSP
     840       850       860       870       880       890         

     900       910       920       930       940       950         
pF1KA0 DVQIHAERFINYNQTVSRMRGIYTAPSGLESTCLVVAYGLDIYQTRVYPSKQFDVLKDDY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DVQIHAERFINYNQTVSRMRGIYTAPSGLESTCLVVAYGLDIYQTRVYPSKQFDVLKDDY
     900       910       920       930       940       950         

     960       970       980       990  
pF1KA0 DYVLISSVLFGLVFATMITKRLAQVKLLNRAWR
       :::::::::::::::::::::::::::::::::
NP_001 DYVLISSVLFGLVFATMITKRLAQVKLLNRAWR
     960       970       980       990  

>>NP_001258358 (OMIM: 616846,616875) ER membrane protein  (971 aa)
 initn: 4700 init1: 4231 opt: 5854  Z-score: 6902.1  bits: 1288.6 E(85289):    0
Smith-Waterman score: 6279; 97.6% identity (97.6% similar) in 993 aa overlap (1-992:1-971)

               10        20        30        40        50        60
pF1KA0 MAAEWASRFWLWATLLIPAAAVYEDQVGKFDWRQQYVGKVKFASLEFSPGSKKLVVATEK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MAAEWASRFWLWATLLIPAAAVYEDQVGKFDWRQQYVGKVKFASLEFSPGSKKLVVATEK
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KA0 NVIAALNSRTGEILWRHVDKGTAEGAVDAMLLHGQDVITVSNGGRIMRSWETNIGGLNWE
       :::::::::::::                       ::::::::::::::::::::::::
NP_001 NVIAALNSRTGEIY----------------------VITVSNGGRIMRSWETNIGGLNWE
               70                              80        90        

              130       140       150       160       170       180
pF1KA0 ITLDSGSFQALGLVGLQESVRYIAVLKKTTLALHHLSSGHLKWVEHLPESDSIHYQMVYS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ITLDSGSFQALGLVGLQESVRYIAVLKKTTLALHHLSSGHLKWVEHLPESDSIHYQMVYS
      100       110       120       130       140       150        

              190       200       210       220       230       240
pF1KA0 YGSGVVWALGVVPFSHVNIVKFNVEDGEIVQQVRVSTPWLQHLSGACGVVDEAVLVCPDP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 YGSGVVWALGVVPFSHVNIVKFNVEDGEIVQQVRVSTPWLQHLSGACGVVDEAVLVCPDP
      160       170       180       190       200       210        

              250       260       270       280       290       300
pF1KA0 SSRSLQTLALETEWELRQIPLQSLDLEFGSGFQPRVLPTQPNPVDASRAQFFLHLSPSHY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SSRSLQTLALETEWELRQIPLQSLDLEFGSGFQPRVLPTQPNPVDASRAQFFLHLSPSHY
      220       230       240       250       260       270        

              310       320       330       340        350         
pF1KA0 ALLQYHYGTLSLLKNFPQTALVSFATTGEKTVAAVMACRNEV-KSSSSEDGSMGSFSEKS
       :::::::::::::::::::::::::::::::::::::::::: :::::::::::::::::
NP_001 ALLQYHYGTLSLLKNFPQTALVSFATTGEKTVAAVMACRNEVQKSSSSEDGSMGSFSEKS
      280       290       300       310       320       330        

     360       370       380       390       400       410         
pF1KA0 SSKDSLACFNQTYTINLYLVETGRRLLDTTITFSLEQSGTRPERLYIQVFLKKDDSVGYR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SSKDSLACFNQTYTINLYLVETGRRLLDTTITFSLEQSGTRPERLYIQVFLKKDDSVGYR
      340       350       360       370       380       390        

     420       430       440       450       460       470         
pF1KA0 ALVQTEDHLLLFLQQLAGKVVLWSREESLAEVVCLEMVDLPLTGAQAELEGEFGKKADGL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ALVQTEDHLLLFLQQLAGKVVLWSREESLAEVVCLEMVDLPLTGAQAELEGEFGKKADGL
      400       410       420       430       440       450        

     480       490       500       510       520       530         
pF1KA0 LGMFLKRLSSQLILLQAWTSHLWKMFYDARKPRSQIKNEINIDTLARDEFNLQKMMVMVT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LGMFLKRLSSQLILLQAWTSHLWKMFYDARKPRSQIKNEINIDTLARDEFNLQKMMVMVT
      460       470       480       490       500       510        

     540       550       560       570       580       590         
pF1KA0 ASGKLFGIESSSGTILWKQYLPNVKPDSSFKLMVQRTTAHFPHPPQCTLLVKDKESGMSS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ASGKLFGIESSSGTILWKQYLPNVKPDSSFKLMVQRTTAHFPHPPQCTLLVKDKESGMSS
      520       530       540       550       560       570        

     600       610       620       630       640       650         
pF1KA0 LYVFNPIFGKWSQVAPPVLKRPILQSLLLPVMDQDYAKVLLLIDDEYKVTAFPATRNVLR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LYVFNPIFGKWSQVAPPVLKRPILQSLLLPVMDQDYAKVLLLIDDEYKVTAFPATRNVLR
      580       590       600       610       620       630        

     660       670       680       690       700       710         
pF1KA0 QLHELAPSIFFYLVDAEQGRLCGYRLRKDLTTELSWELTIPPEVQRIVKVKGKRSSEHVH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QLHELAPSIFFYLVDAEQGRLCGYRLRKDLTTELSWELTIPPEVQRIVKVKGKRSSEHVH
      640       650       660       670       680       690        

     720       730       740       750       760       770         
pF1KA0 SQGRVMGDRSVLYKSLNPNLLAVVTESTDAHHERTFIGIFLIDGVTGRIIHSSVQKKAKG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SQGRVMGDRSVLYKSLNPNLLAVVTESTDAHHERTFIGIFLIDGVTGRIIHSSVQKKAKG
      700       710       720       730       740       750        

     780       790       800       810       820       830         
pF1KA0 PVHIVHSENWVVYQYWNTKARRNEFTVLELYEGTEQYNATAFSSLDRPQLPQVLQQSYIF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PVHIVHSENWVVYQYWNTKARRNEFTVLELYEGTEQYNATAFSSLDRPQLPQVLQQSYIF
      760       770       780       790       800       810        

     840       850       860       870       880       890         
pF1KA0 PSSISAMEATITERGITSRHLLIGLPSGAILSLPKALLDPRRPEIPTEQSREENLIPYSP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PSSISAMEATITERGITSRHLLIGLPSGAILSLPKALLDPRRPEIPTEQSREENLIPYSP
      820       830       840       850       860       870        

     900       910       920       930       940       950         
pF1KA0 DVQIHAERFINYNQTVSRMRGIYTAPSGLESTCLVVAYGLDIYQTRVYPSKQFDVLKDDY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DVQIHAERFINYNQTVSRMRGIYTAPSGLESTCLVVAYGLDIYQTRVYPSKQFDVLKDDY
      880       890       900       910       920       930        

     960       970       980       990  
pF1KA0 DYVLISSVLFGLVFATMITKRLAQVKLLNRAWR
       :::::::::::::::::::::::::::::::::
NP_001 DYVLISSVLFGLVFATMITKRLAQVKLLNRAWR
      940       950       960       970 




992 residues in 1 query   sequences
60827320 residues in 85289 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Wed Nov  2 18:00:56 2016 done: Wed Nov  2 18:00:57 2016
 Total Scan time: 11.340 Total Display time:  0.230

Function used was FASTA [36.3.4 Apr, 2011]
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