Result of FASTA (omim) for
pFN21AE2632
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE2632, 2073 aa
1>>>pF1KE2632 2073 - 2073 aa - 2073 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 13.5822+/-0.000472; mu= -11.8098+/- 0.030
mean_var=499.0051+/-102.677, 0's: 0 Z-trim(122.9): 152 B-trim: 890 in 1/61
Lambda= 0.057415
statistics sampled from 41512 (41710) to 41512 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.754), E-opt: 0.2 (0.489), width: 16
Scan time: 14.650
The best scores are: opt bits E(85289)
XP_016871490 (OMIM: 603736,605880,606170) PREDICTE (2073) 13959 1172.5 0
XP_016871489 (OMIM: 603736,605880,606170) PREDICTE (2073) 13959 1172.5 0
XP_016871492 (OMIM: 603736,605880,606170) PREDICTE (2073) 13959 1172.5 0
XP_016871491 (OMIM: 603736,605880,606170) PREDICTE (2073) 13959 1172.5 0
XP_005269721 (OMIM: 603736,605880,606170) PREDICTE (2073) 13959 1172.5 0
NP_036462 (OMIM: 603736,605880,606170) histone ace (2073) 13959 1172.5 0
XP_016871496 (OMIM: 603736,605880,606170) PREDICTE (1781) 9491 802.4 0
XP_016871495 (OMIM: 603736,605880,606170) PREDICTE (1781) 9491 802.4 0
XP_016871497 (OMIM: 603736,605880,606170) PREDICTE (1781) 9491 802.4 0
NP_001243398 (OMIM: 603736,605880,606170) histone (1781) 9491 802.4 0
XP_016871494 (OMIM: 603736,605880,606170) PREDICTE (1890) 9460 799.8 0
NP_001243397 (OMIM: 603736,605880,606170) histone (1890) 9460 799.8 0
XP_016871498 (OMIM: 603736,605880,606170) PREDICTE (1727) 8206 695.9 9.7e-199
XP_016871493 (OMIM: 603736,605880,606170) PREDICTE (2019) 8206 696.0 1.1e-198
NP_006757 (OMIM: 601408,616268) histone acetyltran (2004) 1776 163.4 2.3e-38
XP_016869352 (OMIM: 601408,616268) PREDICTED: hist (2004) 1776 163.4 2.3e-38
XP_016869353 (OMIM: 601408,616268) PREDICTED: hist (2004) 1776 163.4 2.3e-38
NP_001292807 (OMIM: 601408,616268) histone acetylt ( 815) 1703 157.1 7.6e-37
XP_011542961 (OMIM: 601408,616268) PREDICTED: hist (2041) 1709 157.8 1.1e-36
XP_011542960 (OMIM: 601408,616268) PREDICTED: hist (2048) 1709 157.8 1.1e-36
XP_011542958 (OMIM: 601408,616268) PREDICTED: hist (2048) 1709 157.8 1.1e-36
XP_011542959 (OMIM: 601408,616268) PREDICTED: hist (2048) 1709 157.8 1.1e-36
NP_008998 (OMIM: 609880) histone acetyltransferase ( 611) 1232 117.9 3.4e-25
NP_001186087 (OMIM: 609880) histone acetyltransfer ( 442) 1209 115.9 9.8e-25
XP_011522537 (OMIM: 609880) PREDICTED: histone ace ( 328) 1203 115.3 1.1e-24
NP_001186085 (OMIM: 609880) histone acetyltransfer ( 472) 1203 115.5 1.5e-24
NP_001186086 (OMIM: 609880) histone acetyltransfer ( 501) 1203 115.5 1.5e-24
NP_001186084 (OMIM: 609880) histone acetyltransfer ( 581) 1203 115.5 1.7e-24
XP_011544273 (OMIM: 609912) PREDICTED: histone ace ( 300) 970 96.0 6.6e-19
XP_011544272 (OMIM: 609912) PREDICTED: histone ace ( 300) 970 96.0 6.6e-19
NP_115564 (OMIM: 609912) histone acetyltransferase ( 458) 970 96.2 9.2e-19
XP_006718484 (OMIM: 601409) PREDICTED: histone ace ( 522) 961 95.4 1.7e-18
NP_006379 (OMIM: 601409) histone acetyltransferase ( 513) 952 94.7 2.8e-18
NP_874369 (OMIM: 601409) histone acetyltransferase ( 546) 952 94.7 3e-18
NP_874368 (OMIM: 601409) histone acetyltransferase ( 461) 947 94.3 3.5e-18
NP_892003 (OMIM: 609912) histone acetyltransferase ( 467) 947 94.3 3.5e-18
NP_001193762 (OMIM: 601409) histone acetyltransfer ( 494) 947 94.3 3.7e-18
XP_016873590 (OMIM: 601671) PREDICTED: zinc finger ( 385) 511 58.1 2.2e-07
NP_001317237 (OMIM: 601671) zinc finger protein ub ( 405) 511 58.1 2.3e-07
XP_016873591 (OMIM: 601671) PREDICTED: zinc finger ( 371) 508 57.8 2.6e-07
NP_006259 (OMIM: 601671) zinc finger protein ubi-d ( 391) 508 57.8 2.7e-07
XP_016877159 (OMIM: 601672) PREDICTED: zinc finger ( 378) 485 55.9 9.8e-07
NP_001267471 (OMIM: 601672) zinc finger protein DP ( 378) 485 55.9 9.8e-07
XP_005259349 (OMIM: 601670) PREDICTED: zinc finger ( 369) 478 55.3 1.4e-06
XP_005259346 (OMIM: 601670) PREDICTED: zinc finger ( 397) 478 55.4 1.5e-06
NP_001128628 (OMIM: 601670) zinc finger protein ne ( 332) 475 55.0 1.6e-06
XP_005259347 (OMIM: 601670) PREDICTED: zinc finger ( 388) 475 55.1 1.8e-06
NP_001128627 (OMIM: 601670) zinc finger protein ne ( 414) 475 55.1 1.9e-06
NP_579866 (OMIM: 613069) PHD finger protein 10 iso ( 496) 432 51.6 2.5e-05
NP_060758 (OMIM: 613069) PHD finger protein 10 iso ( 498) 432 51.6 2.6e-05
>>XP_016871490 (OMIM: 603736,605880,606170) PREDICTED: h (2073 aa)
initn: 13959 init1: 13959 opt: 13959 Z-score: 6263.3 bits: 1172.5 E(85289): 0
Smith-Waterman score: 13959; 100.0% identity (100.0% similar) in 2073 aa overlap (1-2073:1-2073)
10 20 30 40 50 60
pF1KE2 MVKLANPLYTEWILEAIQKIKKQKQRPSEERICHAVSTSHGLDKKTVSEQLELSVQDGSV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MVKLANPLYTEWILEAIQKIKKQKQRPSEERICHAVSTSHGLDKKTVSEQLELSVQDGSV
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE2 LKVTNKGLASYKDPDNPGRFSSVKPGTFPKSAKGSRGSCNDLRNVDWNKLLRRAIEGLEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LKVTNKGLASYKDPDNPGRFSSVKPGTFPKSAKGSRGSCNDLRNVDWNKLLRRAIEGLEE
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE2 PNGSSLKNIEKYLRSQSDLTSTTNNPAFQQRLRLGAKRAVNNGRLLKDGPQYRVNYGSLD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PNGSSLKNIEKYLRSQSDLTSTTNNPAFQQRLRLGAKRAVNNGRLLKDGPQYRVNYGSLD
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE2 GKGAPQYPSAFPSSLPPVSLLPHEKDQPRADPIPICSFCLGTKESNREKKPEELLSCADC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GKGAPQYPSAFPSSLPPVSLLPHEKDQPRADPIPICSFCLGTKESNREKKPEELLSCADC
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE2 GSSGHPSCLKFCPELTTNVKALRWQCIECKTCSACRVQGRNADNMLFCDSCDRGFHMECC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GSSGHPSCLKFCPELTTNVKALRWQCIECKTCSACRVQGRNADNMLFCDSCDRGFHMECC
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE2 DPPLSRMPKGMWICQVCRPKKKGRKLLHEKAAQIKRRYAKPIGRPKNKLKQRLLSVTSDE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DPPLSRMPKGMWICQVCRPKKKGRKLLHEKAAQIKRRYAKPIGRPKNKLKQRLLSVTSDE
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE2 GSMNAFTGRGSPGRGQKTKVCTTPSSGHAASGKDSSSRLAVTDPTRPGATTKITTTSTYI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GSMNAFTGRGSPGRGQKTKVCTTPSSGHAASGKDSSSRLAVTDPTRPGATTKITTTSTYI
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE2 SASTLKVNKKTKGLIDGLTKFFTPSPDGRRSRGEIIDFSKHYRPRKKVSQKQSCTSHVLA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SASTLKVNKKTKGLIDGLTKFFTPSPDGRRSRGEIIDFSKHYRPRKKVSQKQSCTSHVLA
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE2 TGTTQKLKPPPSSLPPPTPISGQSPSSQKSSTATSSPSPQSSSSQCSVPSLSSLTTNSQL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TGTTQKLKPPPSSLPPPTPISGQSPSSQKSSTATSSPSPQSSSSQCSVPSLSSLTTNSQL
490 500 510 520 530 540
550 560 570 580 590 600
pF1KE2 KALFDGLSHIYTTQGQSRKKGHPSYAPPKRMRRKTELSSTAKSKAHFFGKRDIRSRFISH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KALFDGLSHIYTTQGQSRKKGHPSYAPPKRMRRKTELSSTAKSKAHFFGKRDIRSRFISH
550 560 570 580 590 600
610 620 630 640 650 660
pF1KE2 SSSSSWGMARGSIFKAIAHFKRTTFLKKHRMLGRLKYKVTPQMGTPSPGKGSLTDGRIKP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SSSSSWGMARGSIFKAIAHFKRTTFLKKHRMLGRLKYKVTPQMGTPSPGKGSLTDGRIKP
610 620 630 640 650 660
670 680 690 700 710 720
pF1KE2 DQDDDTEIKINIKQESADVNVIGNKDVVTEEDLDVFKQAQELSWEKIECESGVEDCGRYP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DQDDDTEIKINIKQESADVNVIGNKDVVTEEDLDVFKQAQELSWEKIECESGVEDCGRYP
670 680 690 700 710 720
730 740 750 760 770 780
pF1KE2 SVIEFGKYEIQTWYSSPYPQEYARLPKLYLCEFCLKYMKSKNILLRHSKKCGWFHPPANE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SVIEFGKYEIQTWYSSPYPQEYARLPKLYLCEFCLKYMKSKNILLRHSKKCGWFHPPANE
730 740 750 760 770 780
790 800 810 820 830 840
pF1KE2 IYRRKDLSVFEVDGNMSKIYCQNLCLLAKLFLDHKTLYYDVEPFLFYVLTKNDEKGCHLV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IYRRKDLSVFEVDGNMSKIYCQNLCLLAKLFLDHKTLYYDVEPFLFYVLTKNDEKGCHLV
790 800 810 820 830 840
850 860 870 880 890 900
pF1KE2 GYFSKEKLCQQKYNVSCIMIMPQHQRQGFGRFLIDFSYLLSRREGQAGSPEKPLSDLGRL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GYFSKEKLCQQKYNVSCIMIMPQHQRQGFGRFLIDFSYLLSRREGQAGSPEKPLSDLGRL
850 860 870 880 890 900
910 920 930 940 950 960
pF1KE2 SYLAYWKSVILEYLYHHHERHISIKAISRATGMCPHDIATTLQHLHMIDKRDGRFVIIRR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SYLAYWKSVILEYLYHHHERHISIKAISRATGMCPHDIATTLQHLHMIDKRDGRFVIIRR
910 920 930 940 950 960
970 980 990 1000 1010 1020
pF1KE2 EKLILSHMEKLKTCSRANELDPDSLRWTPILISNAAVSEEEREAEKEAERLMEQASCWEK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EKLILSHMEKLKTCSRANELDPDSLRWTPILISNAAVSEEEREAEKEAERLMEQASCWEK
970 980 990 1000 1010 1020
1030 1040 1050 1060 1070 1080
pF1KE2 EEQEILSTRANSRQSPAKVQSKNKYLHSPESRPVTGERGQLLELSKESSEEEEEEEDEEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EEQEILSTRANSRQSPAKVQSKNKYLHSPESRPVTGERGQLLELSKESSEEEEEEEDEEE
1030 1040 1050 1060 1070 1080
1090 1100 1110 1120 1130 1140
pF1KE2 EEEEEEEEEDEEEEEEEEEEEEEENIQSSPPRLTKPQSVAIKRKRPFVLKKKRGRKRRRI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EEEEEEEEEDEEEEEEEEEEEEEENIQSSPPRLTKPQSVAIKRKRPFVLKKKRGRKRRRI
1090 1100 1110 1120 1130 1140
1150 1160 1170 1180 1190 1200
pF1KE2 NSSVTTETISETTEVLNEPFDNSDEERPMPQLEPTCEIEVEEDGRKPVLRKAFQHQPGKK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NSSVTTETISETTEVLNEPFDNSDEERPMPQLEPTCEIEVEEDGRKPVLRKAFQHQPGKK
1150 1160 1170 1180 1190 1200
1210 1220 1230 1240 1250 1260
pF1KE2 RQTEEEEGKDNHCFKNADPCRNNMNDDSSNLKEGSKDNPEPLKCKQVWPKGTKRGLSKWR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RQTEEEEGKDNHCFKNADPCRNNMNDDSSNLKEGSKDNPEPLKCKQVWPKGTKRGLSKWR
1210 1220 1230 1240 1250 1260
1270 1280 1290 1300 1310 1320
pF1KE2 QNKERKTGFKLNLYTPPETPMEPDEQVTVEEQKETSEGKTSPSPIRIEEEVKETGEALLP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QNKERKTGFKLNLYTPPETPMEPDEQVTVEEQKETSEGKTSPSPIRIEEEVKETGEALLP
1270 1280 1290 1300 1310 1320
1330 1340 1350 1360 1370 1380
pF1KE2 QEENRREETCAPVSPNTSPGEKPEDDLIKPEEEEEEEEEEEEEEEEEEGEEEEGGGNVEK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QEENRREETCAPVSPNTSPGEKPEDDLIKPEEEEEEEEEEEEEEEEEEGEEEEGGGNVEK
1330 1340 1350 1360 1370 1380
1390 1400 1410 1420 1430 1440
pF1KE2 DPDGAKSQEKEEPEISTEKEDSARLDDHEEEEEEDEEPSHNEDHDADDEDDSHMESAEVE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DPDGAKSQEKEEPEISTEKEDSARLDDHEEEEEEDEEPSHNEDHDADDEDDSHMESAEVE
1390 1400 1410 1420 1430 1440
1450 1460 1470 1480 1490 1500
pF1KE2 KEELPRESFKEVLENQETFLDLNVQPGHSNPEVLMDCGVDLTASCNSEPKELAGDPEAVP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KEELPRESFKEVLENQETFLDLNVQPGHSNPEVLMDCGVDLTASCNSEPKELAGDPEAVP
1450 1460 1470 1480 1490 1500
1510 1520 1530 1540 1550 1560
pF1KE2 ESDEEPPPGEQAQKQDQKNSKEVDTEFKEGNPATMEIDSETVQAVQSLTQESSEQDDTFQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ESDEEPPPGEQAQKQDQKNSKEVDTEFKEGNPATMEIDSETVQAVQSLTQESSEQDDTFQ
1510 1520 1530 1540 1550 1560
1570 1580 1590 1600 1610 1620
pF1KE2 DCAETQEACRSLQNYTRADQSPQIATTLDDCQQSDHSSPVSSVHSHPGQSVRSVNSPSVP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DCAETQEACRSLQNYTRADQSPQIATTLDDCQQSDHSSPVSSVHSHPGQSVRSVNSPSVP
1570 1580 1590 1600 1610 1620
1630 1640 1650 1660 1670 1680
pF1KE2 ALENSYAQISPDQSAISVPSLQNMETSPMMDVPSVSDHSQQVVDSGFSDLGSIESTTENY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ALENSYAQISPDQSAISVPSLQNMETSPMMDVPSVSDHSQQVVDSGFSDLGSIESTTENY
1630 1640 1650 1660 1670 1680
1690 1700 1710 1720 1730 1740
pF1KE2 ENPSSYDSTMGGSICGNGSSQNSCSYSNLTSSSLTQSSCAVTQQMSNISGSCSMLQQTSI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ENPSSYDSTMGGSICGNGSSQNSCSYSNLTSSSLTQSSCAVTQQMSNISGSCSMLQQTSI
1690 1700 1710 1720 1730 1740
1750 1760 1770 1780 1790 1800
pF1KE2 SSPPTCSVKSPQGCVVERPPSSSQQLAQCSMAANFTPPMQLAEIPETSNANIGLYERMGQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SSPPTCSVKSPQGCVVERPPSSSQQLAQCSMAANFTPPMQLAEIPETSNANIGLYERMGQ
1750 1760 1770 1780 1790 1800
1810 1820 1830 1840 1850 1860
pF1KE2 SDFGAGHYPQPSATFSLAKLQQLTNTLIDHSLPYSHSAAVTSYANSASLSTPLSNTGLVQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SDFGAGHYPQPSATFSLAKLQQLTNTLIDHSLPYSHSAAVTSYANSASLSTPLSNTGLVQ
1810 1820 1830 1840 1850 1860
1870 1880 1890 1900 1910 1920
pF1KE2 LSQSPHSVPGGPQAQATMTPPPNLTPPPMNLPPPLLQRNMAASNIGISHSQRLQTQIASK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LSQSPHSVPGGPQAQATMTPPPNLTPPPMNLPPPLLQRNMAASNIGISHSQRLQTQIASK
1870 1880 1890 1900 1910 1920
1930 1940 1950 1960 1970 1980
pF1KE2 GHISMRTKSASLSPAAATHQSQIYGRSQTVAMQGPARTLTMQRGMNMSVNLMPAPAYNVN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GHISMRTKSASLSPAAATHQSQIYGRSQTVAMQGPARTLTMQRGMNMSVNLMPAPAYNVN
1930 1940 1950 1960 1970 1980
1990 2000 2010 2020 2030 2040
pF1KE2 SVNMNMNTLNAMNGYSMSQPMMNSGYHSNHGYMNQTPQYPMQMQMGMMGTQPYAQQPMQT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SVNMNMNTLNAMNGYSMSQPMMNSGYHSNHGYMNQTPQYPMQMQMGMMGTQPYAQQPMQT
1990 2000 2010 2020 2030 2040
2050 2060 2070
pF1KE2 PPHGNMMYTAPGHHGYMNTGMSKQSLNGSYMRR
:::::::::::::::::::::::::::::::::
XP_016 PPHGNMMYTAPGHHGYMNTGMSKQSLNGSYMRR
2050 2060 2070
>>XP_016871489 (OMIM: 603736,605880,606170) PREDICTED: h (2073 aa)
initn: 13959 init1: 13959 opt: 13959 Z-score: 6263.3 bits: 1172.5 E(85289): 0
Smith-Waterman score: 13959; 100.0% identity (100.0% similar) in 2073 aa overlap (1-2073:1-2073)
10 20 30 40 50 60
pF1KE2 MVKLANPLYTEWILEAIQKIKKQKQRPSEERICHAVSTSHGLDKKTVSEQLELSVQDGSV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MVKLANPLYTEWILEAIQKIKKQKQRPSEERICHAVSTSHGLDKKTVSEQLELSVQDGSV
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE2 LKVTNKGLASYKDPDNPGRFSSVKPGTFPKSAKGSRGSCNDLRNVDWNKLLRRAIEGLEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LKVTNKGLASYKDPDNPGRFSSVKPGTFPKSAKGSRGSCNDLRNVDWNKLLRRAIEGLEE
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE2 PNGSSLKNIEKYLRSQSDLTSTTNNPAFQQRLRLGAKRAVNNGRLLKDGPQYRVNYGSLD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PNGSSLKNIEKYLRSQSDLTSTTNNPAFQQRLRLGAKRAVNNGRLLKDGPQYRVNYGSLD
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE2 GKGAPQYPSAFPSSLPPVSLLPHEKDQPRADPIPICSFCLGTKESNREKKPEELLSCADC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GKGAPQYPSAFPSSLPPVSLLPHEKDQPRADPIPICSFCLGTKESNREKKPEELLSCADC
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE2 GSSGHPSCLKFCPELTTNVKALRWQCIECKTCSACRVQGRNADNMLFCDSCDRGFHMECC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GSSGHPSCLKFCPELTTNVKALRWQCIECKTCSACRVQGRNADNMLFCDSCDRGFHMECC
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE2 DPPLSRMPKGMWICQVCRPKKKGRKLLHEKAAQIKRRYAKPIGRPKNKLKQRLLSVTSDE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DPPLSRMPKGMWICQVCRPKKKGRKLLHEKAAQIKRRYAKPIGRPKNKLKQRLLSVTSDE
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE2 GSMNAFTGRGSPGRGQKTKVCTTPSSGHAASGKDSSSRLAVTDPTRPGATTKITTTSTYI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GSMNAFTGRGSPGRGQKTKVCTTPSSGHAASGKDSSSRLAVTDPTRPGATTKITTTSTYI
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE2 SASTLKVNKKTKGLIDGLTKFFTPSPDGRRSRGEIIDFSKHYRPRKKVSQKQSCTSHVLA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SASTLKVNKKTKGLIDGLTKFFTPSPDGRRSRGEIIDFSKHYRPRKKVSQKQSCTSHVLA
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE2 TGTTQKLKPPPSSLPPPTPISGQSPSSQKSSTATSSPSPQSSSSQCSVPSLSSLTTNSQL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TGTTQKLKPPPSSLPPPTPISGQSPSSQKSSTATSSPSPQSSSSQCSVPSLSSLTTNSQL
490 500 510 520 530 540
550 560 570 580 590 600
pF1KE2 KALFDGLSHIYTTQGQSRKKGHPSYAPPKRMRRKTELSSTAKSKAHFFGKRDIRSRFISH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KALFDGLSHIYTTQGQSRKKGHPSYAPPKRMRRKTELSSTAKSKAHFFGKRDIRSRFISH
550 560 570 580 590 600
610 620 630 640 650 660
pF1KE2 SSSSSWGMARGSIFKAIAHFKRTTFLKKHRMLGRLKYKVTPQMGTPSPGKGSLTDGRIKP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SSSSSWGMARGSIFKAIAHFKRTTFLKKHRMLGRLKYKVTPQMGTPSPGKGSLTDGRIKP
610 620 630 640 650 660
670 680 690 700 710 720
pF1KE2 DQDDDTEIKINIKQESADVNVIGNKDVVTEEDLDVFKQAQELSWEKIECESGVEDCGRYP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DQDDDTEIKINIKQESADVNVIGNKDVVTEEDLDVFKQAQELSWEKIECESGVEDCGRYP
670 680 690 700 710 720
730 740 750 760 770 780
pF1KE2 SVIEFGKYEIQTWYSSPYPQEYARLPKLYLCEFCLKYMKSKNILLRHSKKCGWFHPPANE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SVIEFGKYEIQTWYSSPYPQEYARLPKLYLCEFCLKYMKSKNILLRHSKKCGWFHPPANE
730 740 750 760 770 780
790 800 810 820 830 840
pF1KE2 IYRRKDLSVFEVDGNMSKIYCQNLCLLAKLFLDHKTLYYDVEPFLFYVLTKNDEKGCHLV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IYRRKDLSVFEVDGNMSKIYCQNLCLLAKLFLDHKTLYYDVEPFLFYVLTKNDEKGCHLV
790 800 810 820 830 840
850 860 870 880 890 900
pF1KE2 GYFSKEKLCQQKYNVSCIMIMPQHQRQGFGRFLIDFSYLLSRREGQAGSPEKPLSDLGRL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GYFSKEKLCQQKYNVSCIMIMPQHQRQGFGRFLIDFSYLLSRREGQAGSPEKPLSDLGRL
850 860 870 880 890 900
910 920 930 940 950 960
pF1KE2 SYLAYWKSVILEYLYHHHERHISIKAISRATGMCPHDIATTLQHLHMIDKRDGRFVIIRR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SYLAYWKSVILEYLYHHHERHISIKAISRATGMCPHDIATTLQHLHMIDKRDGRFVIIRR
910 920 930 940 950 960
970 980 990 1000 1010 1020
pF1KE2 EKLILSHMEKLKTCSRANELDPDSLRWTPILISNAAVSEEEREAEKEAERLMEQASCWEK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EKLILSHMEKLKTCSRANELDPDSLRWTPILISNAAVSEEEREAEKEAERLMEQASCWEK
970 980 990 1000 1010 1020
1030 1040 1050 1060 1070 1080
pF1KE2 EEQEILSTRANSRQSPAKVQSKNKYLHSPESRPVTGERGQLLELSKESSEEEEEEEDEEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EEQEILSTRANSRQSPAKVQSKNKYLHSPESRPVTGERGQLLELSKESSEEEEEEEDEEE
1030 1040 1050 1060 1070 1080
1090 1100 1110 1120 1130 1140
pF1KE2 EEEEEEEEEDEEEEEEEEEEEEEENIQSSPPRLTKPQSVAIKRKRPFVLKKKRGRKRRRI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EEEEEEEEEDEEEEEEEEEEEEEENIQSSPPRLTKPQSVAIKRKRPFVLKKKRGRKRRRI
1090 1100 1110 1120 1130 1140
1150 1160 1170 1180 1190 1200
pF1KE2 NSSVTTETISETTEVLNEPFDNSDEERPMPQLEPTCEIEVEEDGRKPVLRKAFQHQPGKK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NSSVTTETISETTEVLNEPFDNSDEERPMPQLEPTCEIEVEEDGRKPVLRKAFQHQPGKK
1150 1160 1170 1180 1190 1200
1210 1220 1230 1240 1250 1260
pF1KE2 RQTEEEEGKDNHCFKNADPCRNNMNDDSSNLKEGSKDNPEPLKCKQVWPKGTKRGLSKWR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RQTEEEEGKDNHCFKNADPCRNNMNDDSSNLKEGSKDNPEPLKCKQVWPKGTKRGLSKWR
1210 1220 1230 1240 1250 1260
1270 1280 1290 1300 1310 1320
pF1KE2 QNKERKTGFKLNLYTPPETPMEPDEQVTVEEQKETSEGKTSPSPIRIEEEVKETGEALLP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QNKERKTGFKLNLYTPPETPMEPDEQVTVEEQKETSEGKTSPSPIRIEEEVKETGEALLP
1270 1280 1290 1300 1310 1320
1330 1340 1350 1360 1370 1380
pF1KE2 QEENRREETCAPVSPNTSPGEKPEDDLIKPEEEEEEEEEEEEEEEEEEGEEEEGGGNVEK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QEENRREETCAPVSPNTSPGEKPEDDLIKPEEEEEEEEEEEEEEEEEEGEEEEGGGNVEK
1330 1340 1350 1360 1370 1380
1390 1400 1410 1420 1430 1440
pF1KE2 DPDGAKSQEKEEPEISTEKEDSARLDDHEEEEEEDEEPSHNEDHDADDEDDSHMESAEVE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DPDGAKSQEKEEPEISTEKEDSARLDDHEEEEEEDEEPSHNEDHDADDEDDSHMESAEVE
1390 1400 1410 1420 1430 1440
1450 1460 1470 1480 1490 1500
pF1KE2 KEELPRESFKEVLENQETFLDLNVQPGHSNPEVLMDCGVDLTASCNSEPKELAGDPEAVP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KEELPRESFKEVLENQETFLDLNVQPGHSNPEVLMDCGVDLTASCNSEPKELAGDPEAVP
1450 1460 1470 1480 1490 1500
1510 1520 1530 1540 1550 1560
pF1KE2 ESDEEPPPGEQAQKQDQKNSKEVDTEFKEGNPATMEIDSETVQAVQSLTQESSEQDDTFQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ESDEEPPPGEQAQKQDQKNSKEVDTEFKEGNPATMEIDSETVQAVQSLTQESSEQDDTFQ
1510 1520 1530 1540 1550 1560
1570 1580 1590 1600 1610 1620
pF1KE2 DCAETQEACRSLQNYTRADQSPQIATTLDDCQQSDHSSPVSSVHSHPGQSVRSVNSPSVP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DCAETQEACRSLQNYTRADQSPQIATTLDDCQQSDHSSPVSSVHSHPGQSVRSVNSPSVP
1570 1580 1590 1600 1610 1620
1630 1640 1650 1660 1670 1680
pF1KE2 ALENSYAQISPDQSAISVPSLQNMETSPMMDVPSVSDHSQQVVDSGFSDLGSIESTTENY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ALENSYAQISPDQSAISVPSLQNMETSPMMDVPSVSDHSQQVVDSGFSDLGSIESTTENY
1630 1640 1650 1660 1670 1680
1690 1700 1710 1720 1730 1740
pF1KE2 ENPSSYDSTMGGSICGNGSSQNSCSYSNLTSSSLTQSSCAVTQQMSNISGSCSMLQQTSI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ENPSSYDSTMGGSICGNGSSQNSCSYSNLTSSSLTQSSCAVTQQMSNISGSCSMLQQTSI
1690 1700 1710 1720 1730 1740
1750 1760 1770 1780 1790 1800
pF1KE2 SSPPTCSVKSPQGCVVERPPSSSQQLAQCSMAANFTPPMQLAEIPETSNANIGLYERMGQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SSPPTCSVKSPQGCVVERPPSSSQQLAQCSMAANFTPPMQLAEIPETSNANIGLYERMGQ
1750 1760 1770 1780 1790 1800
1810 1820 1830 1840 1850 1860
pF1KE2 SDFGAGHYPQPSATFSLAKLQQLTNTLIDHSLPYSHSAAVTSYANSASLSTPLSNTGLVQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SDFGAGHYPQPSATFSLAKLQQLTNTLIDHSLPYSHSAAVTSYANSASLSTPLSNTGLVQ
1810 1820 1830 1840 1850 1860
1870 1880 1890 1900 1910 1920
pF1KE2 LSQSPHSVPGGPQAQATMTPPPNLTPPPMNLPPPLLQRNMAASNIGISHSQRLQTQIASK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LSQSPHSVPGGPQAQATMTPPPNLTPPPMNLPPPLLQRNMAASNIGISHSQRLQTQIASK
1870 1880 1890 1900 1910 1920
1930 1940 1950 1960 1970 1980
pF1KE2 GHISMRTKSASLSPAAATHQSQIYGRSQTVAMQGPARTLTMQRGMNMSVNLMPAPAYNVN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GHISMRTKSASLSPAAATHQSQIYGRSQTVAMQGPARTLTMQRGMNMSVNLMPAPAYNVN
1930 1940 1950 1960 1970 1980
1990 2000 2010 2020 2030 2040
pF1KE2 SVNMNMNTLNAMNGYSMSQPMMNSGYHSNHGYMNQTPQYPMQMQMGMMGTQPYAQQPMQT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SVNMNMNTLNAMNGYSMSQPMMNSGYHSNHGYMNQTPQYPMQMQMGMMGTQPYAQQPMQT
1990 2000 2010 2020 2030 2040
2050 2060 2070
pF1KE2 PPHGNMMYTAPGHHGYMNTGMSKQSLNGSYMRR
:::::::::::::::::::::::::::::::::
XP_016 PPHGNMMYTAPGHHGYMNTGMSKQSLNGSYMRR
2050 2060 2070
>>XP_016871492 (OMIM: 603736,605880,606170) PREDICTED: h (2073 aa)
initn: 13959 init1: 13959 opt: 13959 Z-score: 6263.3 bits: 1172.5 E(85289): 0
Smith-Waterman score: 13959; 100.0% identity (100.0% similar) in 2073 aa overlap (1-2073:1-2073)
10 20 30 40 50 60
pF1KE2 MVKLANPLYTEWILEAIQKIKKQKQRPSEERICHAVSTSHGLDKKTVSEQLELSVQDGSV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MVKLANPLYTEWILEAIQKIKKQKQRPSEERICHAVSTSHGLDKKTVSEQLELSVQDGSV
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE2 LKVTNKGLASYKDPDNPGRFSSVKPGTFPKSAKGSRGSCNDLRNVDWNKLLRRAIEGLEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LKVTNKGLASYKDPDNPGRFSSVKPGTFPKSAKGSRGSCNDLRNVDWNKLLRRAIEGLEE
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE2 PNGSSLKNIEKYLRSQSDLTSTTNNPAFQQRLRLGAKRAVNNGRLLKDGPQYRVNYGSLD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PNGSSLKNIEKYLRSQSDLTSTTNNPAFQQRLRLGAKRAVNNGRLLKDGPQYRVNYGSLD
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE2 GKGAPQYPSAFPSSLPPVSLLPHEKDQPRADPIPICSFCLGTKESNREKKPEELLSCADC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GKGAPQYPSAFPSSLPPVSLLPHEKDQPRADPIPICSFCLGTKESNREKKPEELLSCADC
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE2 GSSGHPSCLKFCPELTTNVKALRWQCIECKTCSACRVQGRNADNMLFCDSCDRGFHMECC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GSSGHPSCLKFCPELTTNVKALRWQCIECKTCSACRVQGRNADNMLFCDSCDRGFHMECC
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE2 DPPLSRMPKGMWICQVCRPKKKGRKLLHEKAAQIKRRYAKPIGRPKNKLKQRLLSVTSDE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DPPLSRMPKGMWICQVCRPKKKGRKLLHEKAAQIKRRYAKPIGRPKNKLKQRLLSVTSDE
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE2 GSMNAFTGRGSPGRGQKTKVCTTPSSGHAASGKDSSSRLAVTDPTRPGATTKITTTSTYI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GSMNAFTGRGSPGRGQKTKVCTTPSSGHAASGKDSSSRLAVTDPTRPGATTKITTTSTYI
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE2 SASTLKVNKKTKGLIDGLTKFFTPSPDGRRSRGEIIDFSKHYRPRKKVSQKQSCTSHVLA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SASTLKVNKKTKGLIDGLTKFFTPSPDGRRSRGEIIDFSKHYRPRKKVSQKQSCTSHVLA
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE2 TGTTQKLKPPPSSLPPPTPISGQSPSSQKSSTATSSPSPQSSSSQCSVPSLSSLTTNSQL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TGTTQKLKPPPSSLPPPTPISGQSPSSQKSSTATSSPSPQSSSSQCSVPSLSSLTTNSQL
490 500 510 520 530 540
550 560 570 580 590 600
pF1KE2 KALFDGLSHIYTTQGQSRKKGHPSYAPPKRMRRKTELSSTAKSKAHFFGKRDIRSRFISH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KALFDGLSHIYTTQGQSRKKGHPSYAPPKRMRRKTELSSTAKSKAHFFGKRDIRSRFISH
550 560 570 580 590 600
610 620 630 640 650 660
pF1KE2 SSSSSWGMARGSIFKAIAHFKRTTFLKKHRMLGRLKYKVTPQMGTPSPGKGSLTDGRIKP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SSSSSWGMARGSIFKAIAHFKRTTFLKKHRMLGRLKYKVTPQMGTPSPGKGSLTDGRIKP
610 620 630 640 650 660
670 680 690 700 710 720
pF1KE2 DQDDDTEIKINIKQESADVNVIGNKDVVTEEDLDVFKQAQELSWEKIECESGVEDCGRYP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DQDDDTEIKINIKQESADVNVIGNKDVVTEEDLDVFKQAQELSWEKIECESGVEDCGRYP
670 680 690 700 710 720
730 740 750 760 770 780
pF1KE2 SVIEFGKYEIQTWYSSPYPQEYARLPKLYLCEFCLKYMKSKNILLRHSKKCGWFHPPANE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SVIEFGKYEIQTWYSSPYPQEYARLPKLYLCEFCLKYMKSKNILLRHSKKCGWFHPPANE
730 740 750 760 770 780
790 800 810 820 830 840
pF1KE2 IYRRKDLSVFEVDGNMSKIYCQNLCLLAKLFLDHKTLYYDVEPFLFYVLTKNDEKGCHLV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IYRRKDLSVFEVDGNMSKIYCQNLCLLAKLFLDHKTLYYDVEPFLFYVLTKNDEKGCHLV
790 800 810 820 830 840
850 860 870 880 890 900
pF1KE2 GYFSKEKLCQQKYNVSCIMIMPQHQRQGFGRFLIDFSYLLSRREGQAGSPEKPLSDLGRL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GYFSKEKLCQQKYNVSCIMIMPQHQRQGFGRFLIDFSYLLSRREGQAGSPEKPLSDLGRL
850 860 870 880 890 900
910 920 930 940 950 960
pF1KE2 SYLAYWKSVILEYLYHHHERHISIKAISRATGMCPHDIATTLQHLHMIDKRDGRFVIIRR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SYLAYWKSVILEYLYHHHERHISIKAISRATGMCPHDIATTLQHLHMIDKRDGRFVIIRR
910 920 930 940 950 960
970 980 990 1000 1010 1020
pF1KE2 EKLILSHMEKLKTCSRANELDPDSLRWTPILISNAAVSEEEREAEKEAERLMEQASCWEK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EKLILSHMEKLKTCSRANELDPDSLRWTPILISNAAVSEEEREAEKEAERLMEQASCWEK
970 980 990 1000 1010 1020
1030 1040 1050 1060 1070 1080
pF1KE2 EEQEILSTRANSRQSPAKVQSKNKYLHSPESRPVTGERGQLLELSKESSEEEEEEEDEEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EEQEILSTRANSRQSPAKVQSKNKYLHSPESRPVTGERGQLLELSKESSEEEEEEEDEEE
1030 1040 1050 1060 1070 1080
1090 1100 1110 1120 1130 1140
pF1KE2 EEEEEEEEEDEEEEEEEEEEEEEENIQSSPPRLTKPQSVAIKRKRPFVLKKKRGRKRRRI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EEEEEEEEEDEEEEEEEEEEEEEENIQSSPPRLTKPQSVAIKRKRPFVLKKKRGRKRRRI
1090 1100 1110 1120 1130 1140
1150 1160 1170 1180 1190 1200
pF1KE2 NSSVTTETISETTEVLNEPFDNSDEERPMPQLEPTCEIEVEEDGRKPVLRKAFQHQPGKK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NSSVTTETISETTEVLNEPFDNSDEERPMPQLEPTCEIEVEEDGRKPVLRKAFQHQPGKK
1150 1160 1170 1180 1190 1200
1210 1220 1230 1240 1250 1260
pF1KE2 RQTEEEEGKDNHCFKNADPCRNNMNDDSSNLKEGSKDNPEPLKCKQVWPKGTKRGLSKWR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RQTEEEEGKDNHCFKNADPCRNNMNDDSSNLKEGSKDNPEPLKCKQVWPKGTKRGLSKWR
1210 1220 1230 1240 1250 1260
1270 1280 1290 1300 1310 1320
pF1KE2 QNKERKTGFKLNLYTPPETPMEPDEQVTVEEQKETSEGKTSPSPIRIEEEVKETGEALLP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QNKERKTGFKLNLYTPPETPMEPDEQVTVEEQKETSEGKTSPSPIRIEEEVKETGEALLP
1270 1280 1290 1300 1310 1320
1330 1340 1350 1360 1370 1380
pF1KE2 QEENRREETCAPVSPNTSPGEKPEDDLIKPEEEEEEEEEEEEEEEEEEGEEEEGGGNVEK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QEENRREETCAPVSPNTSPGEKPEDDLIKPEEEEEEEEEEEEEEEEEEGEEEEGGGNVEK
1330 1340 1350 1360 1370 1380
1390 1400 1410 1420 1430 1440
pF1KE2 DPDGAKSQEKEEPEISTEKEDSARLDDHEEEEEEDEEPSHNEDHDADDEDDSHMESAEVE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DPDGAKSQEKEEPEISTEKEDSARLDDHEEEEEEDEEPSHNEDHDADDEDDSHMESAEVE
1390 1400 1410 1420 1430 1440
1450 1460 1470 1480 1490 1500
pF1KE2 KEELPRESFKEVLENQETFLDLNVQPGHSNPEVLMDCGVDLTASCNSEPKELAGDPEAVP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KEELPRESFKEVLENQETFLDLNVQPGHSNPEVLMDCGVDLTASCNSEPKELAGDPEAVP
1450 1460 1470 1480 1490 1500
1510 1520 1530 1540 1550 1560
pF1KE2 ESDEEPPPGEQAQKQDQKNSKEVDTEFKEGNPATMEIDSETVQAVQSLTQESSEQDDTFQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ESDEEPPPGEQAQKQDQKNSKEVDTEFKEGNPATMEIDSETVQAVQSLTQESSEQDDTFQ
1510 1520 1530 1540 1550 1560
1570 1580 1590 1600 1610 1620
pF1KE2 DCAETQEACRSLQNYTRADQSPQIATTLDDCQQSDHSSPVSSVHSHPGQSVRSVNSPSVP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DCAETQEACRSLQNYTRADQSPQIATTLDDCQQSDHSSPVSSVHSHPGQSVRSVNSPSVP
1570 1580 1590 1600 1610 1620
1630 1640 1650 1660 1670 1680
pF1KE2 ALENSYAQISPDQSAISVPSLQNMETSPMMDVPSVSDHSQQVVDSGFSDLGSIESTTENY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ALENSYAQISPDQSAISVPSLQNMETSPMMDVPSVSDHSQQVVDSGFSDLGSIESTTENY
1630 1640 1650 1660 1670 1680
1690 1700 1710 1720 1730 1740
pF1KE2 ENPSSYDSTMGGSICGNGSSQNSCSYSNLTSSSLTQSSCAVTQQMSNISGSCSMLQQTSI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ENPSSYDSTMGGSICGNGSSQNSCSYSNLTSSSLTQSSCAVTQQMSNISGSCSMLQQTSI
1690 1700 1710 1720 1730 1740
1750 1760 1770 1780 1790 1800
pF1KE2 SSPPTCSVKSPQGCVVERPPSSSQQLAQCSMAANFTPPMQLAEIPETSNANIGLYERMGQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SSPPTCSVKSPQGCVVERPPSSSQQLAQCSMAANFTPPMQLAEIPETSNANIGLYERMGQ
1750 1760 1770 1780 1790 1800
1810 1820 1830 1840 1850 1860
pF1KE2 SDFGAGHYPQPSATFSLAKLQQLTNTLIDHSLPYSHSAAVTSYANSASLSTPLSNTGLVQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SDFGAGHYPQPSATFSLAKLQQLTNTLIDHSLPYSHSAAVTSYANSASLSTPLSNTGLVQ
1810 1820 1830 1840 1850 1860
1870 1880 1890 1900 1910 1920
pF1KE2 LSQSPHSVPGGPQAQATMTPPPNLTPPPMNLPPPLLQRNMAASNIGISHSQRLQTQIASK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LSQSPHSVPGGPQAQATMTPPPNLTPPPMNLPPPLLQRNMAASNIGISHSQRLQTQIASK
1870 1880 1890 1900 1910 1920
1930 1940 1950 1960 1970 1980
pF1KE2 GHISMRTKSASLSPAAATHQSQIYGRSQTVAMQGPARTLTMQRGMNMSVNLMPAPAYNVN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GHISMRTKSASLSPAAATHQSQIYGRSQTVAMQGPARTLTMQRGMNMSVNLMPAPAYNVN
1930 1940 1950 1960 1970 1980
1990 2000 2010 2020 2030 2040
pF1KE2 SVNMNMNTLNAMNGYSMSQPMMNSGYHSNHGYMNQTPQYPMQMQMGMMGTQPYAQQPMQT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SVNMNMNTLNAMNGYSMSQPMMNSGYHSNHGYMNQTPQYPMQMQMGMMGTQPYAQQPMQT
1990 2000 2010 2020 2030 2040
2050 2060 2070
pF1KE2 PPHGNMMYTAPGHHGYMNTGMSKQSLNGSYMRR
:::::::::::::::::::::::::::::::::
XP_016 PPHGNMMYTAPGHHGYMNTGMSKQSLNGSYMRR
2050 2060 2070
>>XP_016871491 (OMIM: 603736,605880,606170) PREDICTED: h (2073 aa)
initn: 13959 init1: 13959 opt: 13959 Z-score: 6263.3 bits: 1172.5 E(85289): 0
Smith-Waterman score: 13959; 100.0% identity (100.0% similar) in 2073 aa overlap (1-2073:1-2073)
10 20 30 40 50 60
pF1KE2 MVKLANPLYTEWILEAIQKIKKQKQRPSEERICHAVSTSHGLDKKTVSEQLELSVQDGSV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MVKLANPLYTEWILEAIQKIKKQKQRPSEERICHAVSTSHGLDKKTVSEQLELSVQDGSV
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE2 LKVTNKGLASYKDPDNPGRFSSVKPGTFPKSAKGSRGSCNDLRNVDWNKLLRRAIEGLEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LKVTNKGLASYKDPDNPGRFSSVKPGTFPKSAKGSRGSCNDLRNVDWNKLLRRAIEGLEE
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE2 PNGSSLKNIEKYLRSQSDLTSTTNNPAFQQRLRLGAKRAVNNGRLLKDGPQYRVNYGSLD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PNGSSLKNIEKYLRSQSDLTSTTNNPAFQQRLRLGAKRAVNNGRLLKDGPQYRVNYGSLD
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE2 GKGAPQYPSAFPSSLPPVSLLPHEKDQPRADPIPICSFCLGTKESNREKKPEELLSCADC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GKGAPQYPSAFPSSLPPVSLLPHEKDQPRADPIPICSFCLGTKESNREKKPEELLSCADC
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE2 GSSGHPSCLKFCPELTTNVKALRWQCIECKTCSACRVQGRNADNMLFCDSCDRGFHMECC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GSSGHPSCLKFCPELTTNVKALRWQCIECKTCSACRVQGRNADNMLFCDSCDRGFHMECC
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE2 DPPLSRMPKGMWICQVCRPKKKGRKLLHEKAAQIKRRYAKPIGRPKNKLKQRLLSVTSDE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DPPLSRMPKGMWICQVCRPKKKGRKLLHEKAAQIKRRYAKPIGRPKNKLKQRLLSVTSDE
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE2 GSMNAFTGRGSPGRGQKTKVCTTPSSGHAASGKDSSSRLAVTDPTRPGATTKITTTSTYI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GSMNAFTGRGSPGRGQKTKVCTTPSSGHAASGKDSSSRLAVTDPTRPGATTKITTTSTYI
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE2 SASTLKVNKKTKGLIDGLTKFFTPSPDGRRSRGEIIDFSKHYRPRKKVSQKQSCTSHVLA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SASTLKVNKKTKGLIDGLTKFFTPSPDGRRSRGEIIDFSKHYRPRKKVSQKQSCTSHVLA
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE2 TGTTQKLKPPPSSLPPPTPISGQSPSSQKSSTATSSPSPQSSSSQCSVPSLSSLTTNSQL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TGTTQKLKPPPSSLPPPTPISGQSPSSQKSSTATSSPSPQSSSSQCSVPSLSSLTTNSQL
490 500 510 520 530 540
550 560 570 580 590 600
pF1KE2 KALFDGLSHIYTTQGQSRKKGHPSYAPPKRMRRKTELSSTAKSKAHFFGKRDIRSRFISH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KALFDGLSHIYTTQGQSRKKGHPSYAPPKRMRRKTELSSTAKSKAHFFGKRDIRSRFISH
550 560 570 580 590 600
610 620 630 640 650 660
pF1KE2 SSSSSWGMARGSIFKAIAHFKRTTFLKKHRMLGRLKYKVTPQMGTPSPGKGSLTDGRIKP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SSSSSWGMARGSIFKAIAHFKRTTFLKKHRMLGRLKYKVTPQMGTPSPGKGSLTDGRIKP
610 620 630 640 650 660
670 680 690 700 710 720
pF1KE2 DQDDDTEIKINIKQESADVNVIGNKDVVTEEDLDVFKQAQELSWEKIECESGVEDCGRYP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DQDDDTEIKINIKQESADVNVIGNKDVVTEEDLDVFKQAQELSWEKIECESGVEDCGRYP
670 680 690 700 710 720
730 740 750 760 770 780
pF1KE2 SVIEFGKYEIQTWYSSPYPQEYARLPKLYLCEFCLKYMKSKNILLRHSKKCGWFHPPANE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SVIEFGKYEIQTWYSSPYPQEYARLPKLYLCEFCLKYMKSKNILLRHSKKCGWFHPPANE
730 740 750 760 770 780
790 800 810 820 830 840
pF1KE2 IYRRKDLSVFEVDGNMSKIYCQNLCLLAKLFLDHKTLYYDVEPFLFYVLTKNDEKGCHLV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IYRRKDLSVFEVDGNMSKIYCQNLCLLAKLFLDHKTLYYDVEPFLFYVLTKNDEKGCHLV
790 800 810 820 830 840
850 860 870 880 890 900
pF1KE2 GYFSKEKLCQQKYNVSCIMIMPQHQRQGFGRFLIDFSYLLSRREGQAGSPEKPLSDLGRL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GYFSKEKLCQQKYNVSCIMIMPQHQRQGFGRFLIDFSYLLSRREGQAGSPEKPLSDLGRL
850 860 870 880 890 900
910 920 930 940 950 960
pF1KE2 SYLAYWKSVILEYLYHHHERHISIKAISRATGMCPHDIATTLQHLHMIDKRDGRFVIIRR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SYLAYWKSVILEYLYHHHERHISIKAISRATGMCPHDIATTLQHLHMIDKRDGRFVIIRR
910 920 930 940 950 960
970 980 990 1000 1010 1020
pF1KE2 EKLILSHMEKLKTCSRANELDPDSLRWTPILISNAAVSEEEREAEKEAERLMEQASCWEK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EKLILSHMEKLKTCSRANELDPDSLRWTPILISNAAVSEEEREAEKEAERLMEQASCWEK
970 980 990 1000 1010 1020
1030 1040 1050 1060 1070 1080
pF1KE2 EEQEILSTRANSRQSPAKVQSKNKYLHSPESRPVTGERGQLLELSKESSEEEEEEEDEEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EEQEILSTRANSRQSPAKVQSKNKYLHSPESRPVTGERGQLLELSKESSEEEEEEEDEEE
1030 1040 1050 1060 1070 1080
1090 1100 1110 1120 1130 1140
pF1KE2 EEEEEEEEEDEEEEEEEEEEEEEENIQSSPPRLTKPQSVAIKRKRPFVLKKKRGRKRRRI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EEEEEEEEEDEEEEEEEEEEEEEENIQSSPPRLTKPQSVAIKRKRPFVLKKKRGRKRRRI
1090 1100 1110 1120 1130 1140
1150 1160 1170 1180 1190 1200
pF1KE2 NSSVTTETISETTEVLNEPFDNSDEERPMPQLEPTCEIEVEEDGRKPVLRKAFQHQPGKK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NSSVTTETISETTEVLNEPFDNSDEERPMPQLEPTCEIEVEEDGRKPVLRKAFQHQPGKK
1150 1160 1170 1180 1190 1200
1210 1220 1230 1240 1250 1260
pF1KE2 RQTEEEEGKDNHCFKNADPCRNNMNDDSSNLKEGSKDNPEPLKCKQVWPKGTKRGLSKWR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RQTEEEEGKDNHCFKNADPCRNNMNDDSSNLKEGSKDNPEPLKCKQVWPKGTKRGLSKWR
1210 1220 1230 1240 1250 1260
1270 1280 1290 1300 1310 1320
pF1KE2 QNKERKTGFKLNLYTPPETPMEPDEQVTVEEQKETSEGKTSPSPIRIEEEVKETGEALLP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QNKERKTGFKLNLYTPPETPMEPDEQVTVEEQKETSEGKTSPSPIRIEEEVKETGEALLP
1270 1280 1290 1300 1310 1320
1330 1340 1350 1360 1370 1380
pF1KE2 QEENRREETCAPVSPNTSPGEKPEDDLIKPEEEEEEEEEEEEEEEEEEGEEEEGGGNVEK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QEENRREETCAPVSPNTSPGEKPEDDLIKPEEEEEEEEEEEEEEEEEEGEEEEGGGNVEK
1330 1340 1350 1360 1370 1380
1390 1400 1410 1420 1430 1440
pF1KE2 DPDGAKSQEKEEPEISTEKEDSARLDDHEEEEEEDEEPSHNEDHDADDEDDSHMESAEVE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DPDGAKSQEKEEPEISTEKEDSARLDDHEEEEEEDEEPSHNEDHDADDEDDSHMESAEVE
1390 1400 1410 1420 1430 1440
1450 1460 1470 1480 1490 1500
pF1KE2 KEELPRESFKEVLENQETFLDLNVQPGHSNPEVLMDCGVDLTASCNSEPKELAGDPEAVP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KEELPRESFKEVLENQETFLDLNVQPGHSNPEVLMDCGVDLTASCNSEPKELAGDPEAVP
1450 1460 1470 1480 1490 1500
1510 1520 1530 1540 1550 1560
pF1KE2 ESDEEPPPGEQAQKQDQKNSKEVDTEFKEGNPATMEIDSETVQAVQSLTQESSEQDDTFQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ESDEEPPPGEQAQKQDQKNSKEVDTEFKEGNPATMEIDSETVQAVQSLTQESSEQDDTFQ
1510 1520 1530 1540 1550 1560
1570 1580 1590 1600 1610 1620
pF1KE2 DCAETQEACRSLQNYTRADQSPQIATTLDDCQQSDHSSPVSSVHSHPGQSVRSVNSPSVP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DCAETQEACRSLQNYTRADQSPQIATTLDDCQQSDHSSPVSSVHSHPGQSVRSVNSPSVP
1570 1580 1590 1600 1610 1620
1630 1640 1650 1660 1670 1680
pF1KE2 ALENSYAQISPDQSAISVPSLQNMETSPMMDVPSVSDHSQQVVDSGFSDLGSIESTTENY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ALENSYAQISPDQSAISVPSLQNMETSPMMDVPSVSDHSQQVVDSGFSDLGSIESTTENY
1630 1640 1650 1660 1670 1680
1690 1700 1710 1720 1730 1740
pF1KE2 ENPSSYDSTMGGSICGNGSSQNSCSYSNLTSSSLTQSSCAVTQQMSNISGSCSMLQQTSI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ENPSSYDSTMGGSICGNGSSQNSCSYSNLTSSSLTQSSCAVTQQMSNISGSCSMLQQTSI
1690 1700 1710 1720 1730 1740
1750 1760 1770 1780 1790 1800
pF1KE2 SSPPTCSVKSPQGCVVERPPSSSQQLAQCSMAANFTPPMQLAEIPETSNANIGLYERMGQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SSPPTCSVKSPQGCVVERPPSSSQQLAQCSMAANFTPPMQLAEIPETSNANIGLYERMGQ
1750 1760 1770 1780 1790 1800
1810 1820 1830 1840 1850 1860
pF1KE2 SDFGAGHYPQPSATFSLAKLQQLTNTLIDHSLPYSHSAAVTSYANSASLSTPLSNTGLVQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SDFGAGHYPQPSATFSLAKLQQLTNTLIDHSLPYSHSAAVTSYANSASLSTPLSNTGLVQ
1810 1820 1830 1840 1850 1860
1870 1880 1890 1900 1910 1920
pF1KE2 LSQSPHSVPGGPQAQATMTPPPNLTPPPMNLPPPLLQRNMAASNIGISHSQRLQTQIASK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LSQSPHSVPGGPQAQATMTPPPNLTPPPMNLPPPLLQRNMAASNIGISHSQRLQTQIASK
1870 1880 1890 1900 1910 1920
1930 1940 1950 1960 1970 1980
pF1KE2 GHISMRTKSASLSPAAATHQSQIYGRSQTVAMQGPARTLTMQRGMNMSVNLMPAPAYNVN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GHISMRTKSASLSPAAATHQSQIYGRSQTVAMQGPARTLTMQRGMNMSVNLMPAPAYNVN
1930 1940 1950 1960 1970 1980
1990 2000 2010 2020 2030 2040
pF1KE2 SVNMNMNTLNAMNGYSMSQPMMNSGYHSNHGYMNQTPQYPMQMQMGMMGTQPYAQQPMQT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SVNMNMNTLNAMNGYSMSQPMMNSGYHSNHGYMNQTPQYPMQMQMGMMGTQPYAQQPMQT
1990 2000 2010 2020 2030 2040
2050 2060 2070
pF1KE2 PPHGNMMYTAPGHHGYMNTGMSKQSLNGSYMRR
:::::::::::::::::::::::::::::::::
XP_016 PPHGNMMYTAPGHHGYMNTGMSKQSLNGSYMRR
2050 2060 2070
>>XP_005269721 (OMIM: 603736,605880,606170) PREDICTED: h (2073 aa)
initn: 13959 init1: 13959 opt: 13959 Z-score: 6263.3 bits: 1172.5 E(85289): 0
Smith-Waterman score: 13959; 100.0% identity (100.0% similar) in 2073 aa overlap (1-2073:1-2073)
10 20 30 40 50 60
pF1KE2 MVKLANPLYTEWILEAIQKIKKQKQRPSEERICHAVSTSHGLDKKTVSEQLELSVQDGSV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MVKLANPLYTEWILEAIQKIKKQKQRPSEERICHAVSTSHGLDKKTVSEQLELSVQDGSV
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE2 LKVTNKGLASYKDPDNPGRFSSVKPGTFPKSAKGSRGSCNDLRNVDWNKLLRRAIEGLEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LKVTNKGLASYKDPDNPGRFSSVKPGTFPKSAKGSRGSCNDLRNVDWNKLLRRAIEGLEE
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE2 PNGSSLKNIEKYLRSQSDLTSTTNNPAFQQRLRLGAKRAVNNGRLLKDGPQYRVNYGSLD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 PNGSSLKNIEKYLRSQSDLTSTTNNPAFQQRLRLGAKRAVNNGRLLKDGPQYRVNYGSLD
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE2 GKGAPQYPSAFPSSLPPVSLLPHEKDQPRADPIPICSFCLGTKESNREKKPEELLSCADC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 GKGAPQYPSAFPSSLPPVSLLPHEKDQPRADPIPICSFCLGTKESNREKKPEELLSCADC
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE2 GSSGHPSCLKFCPELTTNVKALRWQCIECKTCSACRVQGRNADNMLFCDSCDRGFHMECC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 GSSGHPSCLKFCPELTTNVKALRWQCIECKTCSACRVQGRNADNMLFCDSCDRGFHMECC
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE2 DPPLSRMPKGMWICQVCRPKKKGRKLLHEKAAQIKRRYAKPIGRPKNKLKQRLLSVTSDE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 DPPLSRMPKGMWICQVCRPKKKGRKLLHEKAAQIKRRYAKPIGRPKNKLKQRLLSVTSDE
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE2 GSMNAFTGRGSPGRGQKTKVCTTPSSGHAASGKDSSSRLAVTDPTRPGATTKITTTSTYI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 GSMNAFTGRGSPGRGQKTKVCTTPSSGHAASGKDSSSRLAVTDPTRPGATTKITTTSTYI
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE2 SASTLKVNKKTKGLIDGLTKFFTPSPDGRRSRGEIIDFSKHYRPRKKVSQKQSCTSHVLA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SASTLKVNKKTKGLIDGLTKFFTPSPDGRRSRGEIIDFSKHYRPRKKVSQKQSCTSHVLA
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE2 TGTTQKLKPPPSSLPPPTPISGQSPSSQKSSTATSSPSPQSSSSQCSVPSLSSLTTNSQL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 TGTTQKLKPPPSSLPPPTPISGQSPSSQKSSTATSSPSPQSSSSQCSVPSLSSLTTNSQL
490 500 510 520 530 540
550 560 570 580 590 600
pF1KE2 KALFDGLSHIYTTQGQSRKKGHPSYAPPKRMRRKTELSSTAKSKAHFFGKRDIRSRFISH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 KALFDGLSHIYTTQGQSRKKGHPSYAPPKRMRRKTELSSTAKSKAHFFGKRDIRSRFISH
550 560 570 580 590 600
610 620 630 640 650 660
pF1KE2 SSSSSWGMARGSIFKAIAHFKRTTFLKKHRMLGRLKYKVTPQMGTPSPGKGSLTDGRIKP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SSSSSWGMARGSIFKAIAHFKRTTFLKKHRMLGRLKYKVTPQMGTPSPGKGSLTDGRIKP
610 620 630 640 650 660
670 680 690 700 710 720
pF1KE2 DQDDDTEIKINIKQESADVNVIGNKDVVTEEDLDVFKQAQELSWEKIECESGVEDCGRYP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 DQDDDTEIKINIKQESADVNVIGNKDVVTEEDLDVFKQAQELSWEKIECESGVEDCGRYP
670 680 690 700 710 720
730 740 750 760 770 780
pF1KE2 SVIEFGKYEIQTWYSSPYPQEYARLPKLYLCEFCLKYMKSKNILLRHSKKCGWFHPPANE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SVIEFGKYEIQTWYSSPYPQEYARLPKLYLCEFCLKYMKSKNILLRHSKKCGWFHPPANE
730 740 750 760 770 780
790 800 810 820 830 840
pF1KE2 IYRRKDLSVFEVDGNMSKIYCQNLCLLAKLFLDHKTLYYDVEPFLFYVLTKNDEKGCHLV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 IYRRKDLSVFEVDGNMSKIYCQNLCLLAKLFLDHKTLYYDVEPFLFYVLTKNDEKGCHLV
790 800 810 820 830 840
850 860 870 880 890 900
pF1KE2 GYFSKEKLCQQKYNVSCIMIMPQHQRQGFGRFLIDFSYLLSRREGQAGSPEKPLSDLGRL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 GYFSKEKLCQQKYNVSCIMIMPQHQRQGFGRFLIDFSYLLSRREGQAGSPEKPLSDLGRL
850 860 870 880 890 900
910 920 930 940 950 960
pF1KE2 SYLAYWKSVILEYLYHHHERHISIKAISRATGMCPHDIATTLQHLHMIDKRDGRFVIIRR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SYLAYWKSVILEYLYHHHERHISIKAISRATGMCPHDIATTLQHLHMIDKRDGRFVIIRR
910 920 930 940 950 960
970 980 990 1000 1010 1020
pF1KE2 EKLILSHMEKLKTCSRANELDPDSLRWTPILISNAAVSEEEREAEKEAERLMEQASCWEK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 EKLILSHMEKLKTCSRANELDPDSLRWTPILISNAAVSEEEREAEKEAERLMEQASCWEK
970 980 990 1000 1010 1020
1030 1040 1050 1060 1070 1080
pF1KE2 EEQEILSTRANSRQSPAKVQSKNKYLHSPESRPVTGERGQLLELSKESSEEEEEEEDEEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 EEQEILSTRANSRQSPAKVQSKNKYLHSPESRPVTGERGQLLELSKESSEEEEEEEDEEE
1030 1040 1050 1060 1070 1080
1090 1100 1110 1120 1130 1140
pF1KE2 EEEEEEEEEDEEEEEEEEEEEEEENIQSSPPRLTKPQSVAIKRKRPFVLKKKRGRKRRRI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 EEEEEEEEEDEEEEEEEEEEEEEENIQSSPPRLTKPQSVAIKRKRPFVLKKKRGRKRRRI
1090 1100 1110 1120 1130 1140
1150 1160 1170 1180 1190 1200
pF1KE2 NSSVTTETISETTEVLNEPFDNSDEERPMPQLEPTCEIEVEEDGRKPVLRKAFQHQPGKK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 NSSVTTETISETTEVLNEPFDNSDEERPMPQLEPTCEIEVEEDGRKPVLRKAFQHQPGKK
1150 1160 1170 1180 1190 1200
1210 1220 1230 1240 1250 1260
pF1KE2 RQTEEEEGKDNHCFKNADPCRNNMNDDSSNLKEGSKDNPEPLKCKQVWPKGTKRGLSKWR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 RQTEEEEGKDNHCFKNADPCRNNMNDDSSNLKEGSKDNPEPLKCKQVWPKGTKRGLSKWR
1210 1220 1230 1240 1250 1260
1270 1280 1290 1300 1310 1320
pF1KE2 QNKERKTGFKLNLYTPPETPMEPDEQVTVEEQKETSEGKTSPSPIRIEEEVKETGEALLP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 QNKERKTGFKLNLYTPPETPMEPDEQVTVEEQKETSEGKTSPSPIRIEEEVKETGEALLP
1270 1280 1290 1300 1310 1320
1330 1340 1350 1360 1370 1380
pF1KE2 QEENRREETCAPVSPNTSPGEKPEDDLIKPEEEEEEEEEEEEEEEEEEGEEEEGGGNVEK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 QEENRREETCAPVSPNTSPGEKPEDDLIKPEEEEEEEEEEEEEEEEEEGEEEEGGGNVEK
1330 1340 1350 1360 1370 1380
1390 1400 1410 1420 1430 1440
pF1KE2 DPDGAKSQEKEEPEISTEKEDSARLDDHEEEEEEDEEPSHNEDHDADDEDDSHMESAEVE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 DPDGAKSQEKEEPEISTEKEDSARLDDHEEEEEEDEEPSHNEDHDADDEDDSHMESAEVE
1390 1400 1410 1420 1430 1440
1450 1460 1470 1480 1490 1500
pF1KE2 KEELPRESFKEVLENQETFLDLNVQPGHSNPEVLMDCGVDLTASCNSEPKELAGDPEAVP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 KEELPRESFKEVLENQETFLDLNVQPGHSNPEVLMDCGVDLTASCNSEPKELAGDPEAVP
1450 1460 1470 1480 1490 1500
1510 1520 1530 1540 1550 1560
pF1KE2 ESDEEPPPGEQAQKQDQKNSKEVDTEFKEGNPATMEIDSETVQAVQSLTQESSEQDDTFQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 ESDEEPPPGEQAQKQDQKNSKEVDTEFKEGNPATMEIDSETVQAVQSLTQESSEQDDTFQ
1510 1520 1530 1540 1550 1560
1570 1580 1590 1600 1610 1620
pF1KE2 DCAETQEACRSLQNYTRADQSPQIATTLDDCQQSDHSSPVSSVHSHPGQSVRSVNSPSVP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 DCAETQEACRSLQNYTRADQSPQIATTLDDCQQSDHSSPVSSVHSHPGQSVRSVNSPSVP
1570 1580 1590 1600 1610 1620
1630 1640 1650 1660 1670 1680
pF1KE2 ALENSYAQISPDQSAISVPSLQNMETSPMMDVPSVSDHSQQVVDSGFSDLGSIESTTENY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 ALENSYAQISPDQSAISVPSLQNMETSPMMDVPSVSDHSQQVVDSGFSDLGSIESTTENY
1630 1640 1650 1660 1670 1680
1690 1700 1710 1720 1730 1740
pF1KE2 ENPSSYDSTMGGSICGNGSSQNSCSYSNLTSSSLTQSSCAVTQQMSNISGSCSMLQQTSI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 ENPSSYDSTMGGSICGNGSSQNSCSYSNLTSSSLTQSSCAVTQQMSNISGSCSMLQQTSI
1690 1700 1710 1720 1730 1740
1750 1760 1770 1780 1790 1800
pF1KE2 SSPPTCSVKSPQGCVVERPPSSSQQLAQCSMAANFTPPMQLAEIPETSNANIGLYERMGQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SSPPTCSVKSPQGCVVERPPSSSQQLAQCSMAANFTPPMQLAEIPETSNANIGLYERMGQ
1750 1760 1770 1780 1790 1800
1810 1820 1830 1840 1850 1860
pF1KE2 SDFGAGHYPQPSATFSLAKLQQLTNTLIDHSLPYSHSAAVTSYANSASLSTPLSNTGLVQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SDFGAGHYPQPSATFSLAKLQQLTNTLIDHSLPYSHSAAVTSYANSASLSTPLSNTGLVQ
1810 1820 1830 1840 1850 1860
1870 1880 1890 1900 1910 1920
pF1KE2 LSQSPHSVPGGPQAQATMTPPPNLTPPPMNLPPPLLQRNMAASNIGISHSQRLQTQIASK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LSQSPHSVPGGPQAQATMTPPPNLTPPPMNLPPPLLQRNMAASNIGISHSQRLQTQIASK
1870 1880 1890 1900 1910 1920
1930 1940 1950 1960 1970 1980
pF1KE2 GHISMRTKSASLSPAAATHQSQIYGRSQTVAMQGPARTLTMQRGMNMSVNLMPAPAYNVN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 GHISMRTKSASLSPAAATHQSQIYGRSQTVAMQGPARTLTMQRGMNMSVNLMPAPAYNVN
1930 1940 1950 1960 1970 1980
1990 2000 2010 2020 2030 2040
pF1KE2 SVNMNMNTLNAMNGYSMSQPMMNSGYHSNHGYMNQTPQYPMQMQMGMMGTQPYAQQPMQT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SVNMNMNTLNAMNGYSMSQPMMNSGYHSNHGYMNQTPQYPMQMQMGMMGTQPYAQQPMQT
1990 2000 2010 2020 2030 2040
2050 2060 2070
pF1KE2 PPHGNMMYTAPGHHGYMNTGMSKQSLNGSYMRR
:::::::::::::::::::::::::::::::::
XP_005 PPHGNMMYTAPGHHGYMNTGMSKQSLNGSYMRR
2050 2060 2070
>>NP_036462 (OMIM: 603736,605880,606170) histone acetylt (2073 aa)
initn: 13959 init1: 13959 opt: 13959 Z-score: 6263.3 bits: 1172.5 E(85289): 0
Smith-Waterman score: 13959; 100.0% identity (100.0% similar) in 2073 aa overlap (1-2073:1-2073)
10 20 30 40 50 60
pF1KE2 MVKLANPLYTEWILEAIQKIKKQKQRPSEERICHAVSTSHGLDKKTVSEQLELSVQDGSV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 MVKLANPLYTEWILEAIQKIKKQKQRPSEERICHAVSTSHGLDKKTVSEQLELSVQDGSV
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE2 LKVTNKGLASYKDPDNPGRFSSVKPGTFPKSAKGSRGSCNDLRNVDWNKLLRRAIEGLEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 LKVTNKGLASYKDPDNPGRFSSVKPGTFPKSAKGSRGSCNDLRNVDWNKLLRRAIEGLEE
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE2 PNGSSLKNIEKYLRSQSDLTSTTNNPAFQQRLRLGAKRAVNNGRLLKDGPQYRVNYGSLD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 PNGSSLKNIEKYLRSQSDLTSTTNNPAFQQRLRLGAKRAVNNGRLLKDGPQYRVNYGSLD
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE2 GKGAPQYPSAFPSSLPPVSLLPHEKDQPRADPIPICSFCLGTKESNREKKPEELLSCADC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 GKGAPQYPSAFPSSLPPVSLLPHEKDQPRADPIPICSFCLGTKESNREKKPEELLSCADC
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE2 GSSGHPSCLKFCPELTTNVKALRWQCIECKTCSACRVQGRNADNMLFCDSCDRGFHMECC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 GSSGHPSCLKFCPELTTNVKALRWQCIECKTCSACRVQGRNADNMLFCDSCDRGFHMECC
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE2 DPPLSRMPKGMWICQVCRPKKKGRKLLHEKAAQIKRRYAKPIGRPKNKLKQRLLSVTSDE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 DPPLSRMPKGMWICQVCRPKKKGRKLLHEKAAQIKRRYAKPIGRPKNKLKQRLLSVTSDE
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE2 GSMNAFTGRGSPGRGQKTKVCTTPSSGHAASGKDSSSRLAVTDPTRPGATTKITTTSTYI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 GSMNAFTGRGSPGRGQKTKVCTTPSSGHAASGKDSSSRLAVTDPTRPGATTKITTTSTYI
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE2 SASTLKVNKKTKGLIDGLTKFFTPSPDGRRSRGEIIDFSKHYRPRKKVSQKQSCTSHVLA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 SASTLKVNKKTKGLIDGLTKFFTPSPDGRRSRGEIIDFSKHYRPRKKVSQKQSCTSHVLA
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE2 TGTTQKLKPPPSSLPPPTPISGQSPSSQKSSTATSSPSPQSSSSQCSVPSLSSLTTNSQL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 TGTTQKLKPPPSSLPPPTPISGQSPSSQKSSTATSSPSPQSSSSQCSVPSLSSLTTNSQL
490 500 510 520 530 540
550 560 570 580 590 600
pF1KE2 KALFDGLSHIYTTQGQSRKKGHPSYAPPKRMRRKTELSSTAKSKAHFFGKRDIRSRFISH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 KALFDGLSHIYTTQGQSRKKGHPSYAPPKRMRRKTELSSTAKSKAHFFGKRDIRSRFISH
550 560 570 580 590 600
610 620 630 640 650 660
pF1KE2 SSSSSWGMARGSIFKAIAHFKRTTFLKKHRMLGRLKYKVTPQMGTPSPGKGSLTDGRIKP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 SSSSSWGMARGSIFKAIAHFKRTTFLKKHRMLGRLKYKVTPQMGTPSPGKGSLTDGRIKP
610 620 630 640 650 660
670 680 690 700 710 720
pF1KE2 DQDDDTEIKINIKQESADVNVIGNKDVVTEEDLDVFKQAQELSWEKIECESGVEDCGRYP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 DQDDDTEIKINIKQESADVNVIGNKDVVTEEDLDVFKQAQELSWEKIECESGVEDCGRYP
670 680 690 700 710 720
730 740 750 760 770 780
pF1KE2 SVIEFGKYEIQTWYSSPYPQEYARLPKLYLCEFCLKYMKSKNILLRHSKKCGWFHPPANE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 SVIEFGKYEIQTWYSSPYPQEYARLPKLYLCEFCLKYMKSKNILLRHSKKCGWFHPPANE
730 740 750 760 770 780
790 800 810 820 830 840
pF1KE2 IYRRKDLSVFEVDGNMSKIYCQNLCLLAKLFLDHKTLYYDVEPFLFYVLTKNDEKGCHLV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 IYRRKDLSVFEVDGNMSKIYCQNLCLLAKLFLDHKTLYYDVEPFLFYVLTKNDEKGCHLV
790 800 810 820 830 840
850 860 870 880 890 900
pF1KE2 GYFSKEKLCQQKYNVSCIMIMPQHQRQGFGRFLIDFSYLLSRREGQAGSPEKPLSDLGRL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 GYFSKEKLCQQKYNVSCIMIMPQHQRQGFGRFLIDFSYLLSRREGQAGSPEKPLSDLGRL
850 860 870 880 890 900
910 920 930 940 950 960
pF1KE2 SYLAYWKSVILEYLYHHHERHISIKAISRATGMCPHDIATTLQHLHMIDKRDGRFVIIRR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 SYLAYWKSVILEYLYHHHERHISIKAISRATGMCPHDIATTLQHLHMIDKRDGRFVIIRR
910 920 930 940 950 960
970 980 990 1000 1010 1020
pF1KE2 EKLILSHMEKLKTCSRANELDPDSLRWTPILISNAAVSEEEREAEKEAERLMEQASCWEK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 EKLILSHMEKLKTCSRANELDPDSLRWTPILISNAAVSEEEREAEKEAERLMEQASCWEK
970 980 990 1000 1010 1020
1030 1040 1050 1060 1070 1080
pF1KE2 EEQEILSTRANSRQSPAKVQSKNKYLHSPESRPVTGERGQLLELSKESSEEEEEEEDEEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 EEQEILSTRANSRQSPAKVQSKNKYLHSPESRPVTGERGQLLELSKESSEEEEEEEDEEE
1030 1040 1050 1060 1070 1080
1090 1100 1110 1120 1130 1140
pF1KE2 EEEEEEEEEDEEEEEEEEEEEEEENIQSSPPRLTKPQSVAIKRKRPFVLKKKRGRKRRRI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 EEEEEEEEEDEEEEEEEEEEEEEENIQSSPPRLTKPQSVAIKRKRPFVLKKKRGRKRRRI
1090 1100 1110 1120 1130 1140
1150 1160 1170 1180 1190 1200
pF1KE2 NSSVTTETISETTEVLNEPFDNSDEERPMPQLEPTCEIEVEEDGRKPVLRKAFQHQPGKK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 NSSVTTETISETTEVLNEPFDNSDEERPMPQLEPTCEIEVEEDGRKPVLRKAFQHQPGKK
1150 1160 1170 1180 1190 1200
1210 1220 1230 1240 1250 1260
pF1KE2 RQTEEEEGKDNHCFKNADPCRNNMNDDSSNLKEGSKDNPEPLKCKQVWPKGTKRGLSKWR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 RQTEEEEGKDNHCFKNADPCRNNMNDDSSNLKEGSKDNPEPLKCKQVWPKGTKRGLSKWR
1210 1220 1230 1240 1250 1260
1270 1280 1290 1300 1310 1320
pF1KE2 QNKERKTGFKLNLYTPPETPMEPDEQVTVEEQKETSEGKTSPSPIRIEEEVKETGEALLP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 QNKERKTGFKLNLYTPPETPMEPDEQVTVEEQKETSEGKTSPSPIRIEEEVKETGEALLP
1270 1280 1290 1300 1310 1320
1330 1340 1350 1360 1370 1380
pF1KE2 QEENRREETCAPVSPNTSPGEKPEDDLIKPEEEEEEEEEEEEEEEEEEGEEEEGGGNVEK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 QEENRREETCAPVSPNTSPGEKPEDDLIKPEEEEEEEEEEEEEEEEEEGEEEEGGGNVEK
1330 1340 1350 1360 1370 1380
1390 1400 1410 1420 1430 1440
pF1KE2 DPDGAKSQEKEEPEISTEKEDSARLDDHEEEEEEDEEPSHNEDHDADDEDDSHMESAEVE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 DPDGAKSQEKEEPEISTEKEDSARLDDHEEEEEEDEEPSHNEDHDADDEDDSHMESAEVE
1390 1400 1410 1420 1430 1440
1450 1460 1470 1480 1490 1500
pF1KE2 KEELPRESFKEVLENQETFLDLNVQPGHSNPEVLMDCGVDLTASCNSEPKELAGDPEAVP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 KEELPRESFKEVLENQETFLDLNVQPGHSNPEVLMDCGVDLTASCNSEPKELAGDPEAVP
1450 1460 1470 1480 1490 1500
1510 1520 1530 1540 1550 1560
pF1KE2 ESDEEPPPGEQAQKQDQKNSKEVDTEFKEGNPATMEIDSETVQAVQSLTQESSEQDDTFQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 ESDEEPPPGEQAQKQDQKNSKEVDTEFKEGNPATMEIDSETVQAVQSLTQESSEQDDTFQ
1510 1520 1530 1540 1550 1560
1570 1580 1590 1600 1610 1620
pF1KE2 DCAETQEACRSLQNYTRADQSPQIATTLDDCQQSDHSSPVSSVHSHPGQSVRSVNSPSVP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 DCAETQEACRSLQNYTRADQSPQIATTLDDCQQSDHSSPVSSVHSHPGQSVRSVNSPSVP
1570 1580 1590 1600 1610 1620
1630 1640 1650 1660 1670 1680
pF1KE2 ALENSYAQISPDQSAISVPSLQNMETSPMMDVPSVSDHSQQVVDSGFSDLGSIESTTENY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 ALENSYAQISPDQSAISVPSLQNMETSPMMDVPSVSDHSQQVVDSGFSDLGSIESTTENY
1630 1640 1650 1660 1670 1680
1690 1700 1710 1720 1730 1740
pF1KE2 ENPSSYDSTMGGSICGNGSSQNSCSYSNLTSSSLTQSSCAVTQQMSNISGSCSMLQQTSI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 ENPSSYDSTMGGSICGNGSSQNSCSYSNLTSSSLTQSSCAVTQQMSNISGSCSMLQQTSI
1690 1700 1710 1720 1730 1740
1750 1760 1770 1780 1790 1800
pF1KE2 SSPPTCSVKSPQGCVVERPPSSSQQLAQCSMAANFTPPMQLAEIPETSNANIGLYERMGQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 SSPPTCSVKSPQGCVVERPPSSSQQLAQCSMAANFTPPMQLAEIPETSNANIGLYERMGQ
1750 1760 1770 1780 1790 1800
1810 1820 1830 1840 1850 1860
pF1KE2 SDFGAGHYPQPSATFSLAKLQQLTNTLIDHSLPYSHSAAVTSYANSASLSTPLSNTGLVQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 SDFGAGHYPQPSATFSLAKLQQLTNTLIDHSLPYSHSAAVTSYANSASLSTPLSNTGLVQ
1810 1820 1830 1840 1850 1860
1870 1880 1890 1900 1910 1920
pF1KE2 LSQSPHSVPGGPQAQATMTPPPNLTPPPMNLPPPLLQRNMAASNIGISHSQRLQTQIASK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 LSQSPHSVPGGPQAQATMTPPPNLTPPPMNLPPPLLQRNMAASNIGISHSQRLQTQIASK
1870 1880 1890 1900 1910 1920
1930 1940 1950 1960 1970 1980
pF1KE2 GHISMRTKSASLSPAAATHQSQIYGRSQTVAMQGPARTLTMQRGMNMSVNLMPAPAYNVN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 GHISMRTKSASLSPAAATHQSQIYGRSQTVAMQGPARTLTMQRGMNMSVNLMPAPAYNVN
1930 1940 1950 1960 1970 1980
1990 2000 2010 2020 2030 2040
pF1KE2 SVNMNMNTLNAMNGYSMSQPMMNSGYHSNHGYMNQTPQYPMQMQMGMMGTQPYAQQPMQT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 SVNMNMNTLNAMNGYSMSQPMMNSGYHSNHGYMNQTPQYPMQMQMGMMGTQPYAQQPMQT
1990 2000 2010 2020 2030 2040
2050 2060 2070
pF1KE2 PPHGNMMYTAPGHHGYMNTGMSKQSLNGSYMRR
:::::::::::::::::::::::::::::::::
NP_036 PPHGNMMYTAPGHHGYMNTGMSKQSLNGSYMRR
2050 2060 2070
>>XP_016871496 (OMIM: 603736,605880,606170) PREDICTED: h (1781 aa)
initn: 9460 init1: 9460 opt: 9491 Z-score: 4264.1 bits: 802.4 E(85289): 0
Smith-Waterman score: 11450; 85.9% identity (85.9% similar) in 2073 aa overlap (1-2073:1-1781)
10 20 30 40 50 60
pF1KE2 MVKLANPLYTEWILEAIQKIKKQKQRPSEERICHAVSTSHGLDKKTVSEQLELSVQDGSV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MVKLANPLYTEWILEAIQKIKKQKQRPSEERICHAVSTSHGLDKKTVSEQLELSVQDGSV
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE2 LKVTNKGLASYKDPDNPGRFSSVKPGTFPKSAKGSRGSCNDLRNVDWNKLLRRAIEGLEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LKVTNKGLASYKDPDNPGRFSSVKPGTFPKSAKGSRGSCNDLRNVDWNKLLRRAIEGLEE
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE2 PNGSSLKNIEKYLRSQSDLTSTTNNPAFQQRLRLGAKRAVNNGRLLKDGPQYRVNYGSLD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PNGSSLKNIEKYLRSQSDLTSTTNNPAFQQRLRLGAKRAVNNGRLLKDGPQYRVNYGSLD
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE2 GKGAPQYPSAFPSSLPPVSLLPHEKDQPRADPIPICSFCLGTKESNREKKPEELLSCADC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GKGAPQYPSAFPSSLPPVSLLPHEKDQPRADPIPICSFCLGTKESNREKKPEELLSCADC
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE2 GSSGHPSCLKFCPELTTNVKALRWQCIECKTCSACRVQGRNADNMLFCDSCDRGFHMECC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GSSGHPSCLKFCPELTTNVKALRWQCIECKTCSACRVQGRNADNMLFCDSCDRGFHMECC
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE2 DPPLSRMPKGMWICQVCRPKKKGRKLLHEKAAQIKRRYAKPIGRPKNKLKQRLLSVTSDE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DPPLSRMPKGMWICQVCRPKKKGRKLLHEKAAQIKRRYAKPIGRPKNKLKQRLLSVTSDE
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE2 GSMNAFTGRGSPGRGQKTKVCTTPSSGHAASGKDSSSRLAVTDPTRPGATTKITTTSTYI
::::::::::::
XP_016 GSMNAFTGRGSP------------------------------------------------
370
430 440 450 460 470 480
pF1KE2 SASTLKVNKKTKGLIDGLTKFFTPSPDGRRSRGEIIDFSKHYRPRKKVSQKQSCTSHVLA
XP_016 ------------------------------------------------------------
490 500 510 520 530 540
pF1KE2 TGTTQKLKPPPSSLPPPTPISGQSPSSQKSSTATSSPSPQSSSSQCSVPSLSSLTTNSQL
XP_016 ------------------------------------------------------------
550 560 570 580 590 600
pF1KE2 KALFDGLSHIYTTQGQSRKKGHPSYAPPKRMRRKTELSSTAKSKAHFFGKRDIRSRFISH
XP_016 ------------------------------------------------------------
610 620 630 640 650 660
pF1KE2 SSSSSWGMARGSIFKAIAHFKRTTFLKKHRMLGRLKYKVTPQMGTPSPGKGSLTDGRIKP
XP_016 ------------------------------------------------------------
670 680 690 700 710 720
pF1KE2 DQDDDTEIKINIKQESADVNVIGNKDVVTEEDLDVFKQAQELSWEKIECESGVEDCGRYP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ----DTEIKINIKQESADVNVIGNKDVVTEEDLDVFKQAQELSWEKIECESGVEDCGRYP
380 390 400 410 420
730 740 750 760 770 780
pF1KE2 SVIEFGKYEIQTWYSSPYPQEYARLPKLYLCEFCLKYMKSKNILLRHSKKCGWFHPPANE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SVIEFGKYEIQTWYSSPYPQEYARLPKLYLCEFCLKYMKSKNILLRHSKKCGWFHPPANE
430 440 450 460 470 480
790 800 810 820 830 840
pF1KE2 IYRRKDLSVFEVDGNMSKIYCQNLCLLAKLFLDHKTLYYDVEPFLFYVLTKNDEKGCHLV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IYRRKDLSVFEVDGNMSKIYCQNLCLLAKLFLDHKTLYYDVEPFLFYVLTKNDEKGCHLV
490 500 510 520 530 540
850 860 870 880 890 900
pF1KE2 GYFSKEKLCQQKYNVSCIMIMPQHQRQGFGRFLIDFSYLLSRREGQAGSPEKPLSDLGRL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GYFSKEKLCQQKYNVSCIMIMPQHQRQGFGRFLIDFSYLLSRREGQAGSPEKPLSDLGRL
550 560 570 580 590 600
910 920 930 940 950 960
pF1KE2 SYLAYWKSVILEYLYHHHERHISIKAISRATGMCPHDIATTLQHLHMIDKRDGRFVIIRR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SYLAYWKSVILEYLYHHHERHISIKAISRATGMCPHDIATTLQHLHMIDKRDGRFVIIRR
610 620 630 640 650 660
970 980 990 1000 1010 1020
pF1KE2 EKLILSHMEKLKTCSRANELDPDSLRWTPILISNAAVSEEEREAEKEAERLMEQASCWEK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EKLILSHMEKLKTCSRANELDPDSLRWTPILISNAAVSEEEREAEKEAERLMEQASCWEK
670 680 690 700 710 720
1030 1040 1050 1060 1070 1080
pF1KE2 EEQEILSTRANSRQSPAKVQSKNKYLHSPESRPVTGERGQLLELSKESSEEEEEEEDEEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EEQEILSTRANSRQSPAKVQSKNKYLHSPESRPVTGERGQLLELSKESSEEEEEEEDEEE
730 740 750 760 770 780
1090 1100 1110 1120 1130 1140
pF1KE2 EEEEEEEEEDEEEEEEEEEEEEEENIQSSPPRLTKPQSVAIKRKRPFVLKKKRGRKRRRI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EEEEEEEEEDEEEEEEEEEEEEEENIQSSPPRLTKPQSVAIKRKRPFVLKKKRGRKRRRI
790 800 810 820 830 840
1150 1160 1170 1180 1190 1200
pF1KE2 NSSVTTETISETTEVLNEPFDNSDEERPMPQLEPTCEIEVEEDGRKPVLRKAFQHQPGKK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NSSVTTETISETTEVLNEPFDNSDEERPMPQLEPTCEIEVEEDGRKPVLRKAFQHQPGKK
850 860 870 880 890 900
1210 1220 1230 1240 1250 1260
pF1KE2 RQTEEEEGKDNHCFKNADPCRNNMNDDSSNLKEGSKDNPEPLKCKQVWPKGTKRGLSKWR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RQTEEEEGKDNHCFKNADPCRNNMNDDSSNLKEGSKDNPEPLKCKQVWPKGTKRGLSKWR
910 920 930 940 950 960
1270 1280 1290 1300 1310 1320
pF1KE2 QNKERKTGFKLNLYTPPETPMEPDEQVTVEEQKETSEGKTSPSPIRIEEEVKETGEALLP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QNKERKTGFKLNLYTPPETPMEPDEQVTVEEQKETSEGKTSPSPIRIEEEVKETGEALLP
970 980 990 1000 1010 1020
1330 1340 1350 1360 1370 1380
pF1KE2 QEENRREETCAPVSPNTSPGEKPEDDLIKPEEEEEEEEEEEEEEEEEEGEEEEGGGNVEK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QEENRREETCAPVSPNTSPGEKPEDDLIKPEEEEEEEEEEEEEEEEEEGEEEEGGGNVEK
1030 1040 1050 1060 1070 1080
1390 1400 1410 1420 1430 1440
pF1KE2 DPDGAKSQEKEEPEISTEKEDSARLDDHEEEEEEDEEPSHNEDHDADDEDDSHMESAEVE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DPDGAKSQEKEEPEISTEKEDSARLDDHEEEEEEDEEPSHNEDHDADDEDDSHMESAEVE
1090 1100 1110 1120 1130 1140
1450 1460 1470 1480 1490 1500
pF1KE2 KEELPRESFKEVLENQETFLDLNVQPGHSNPEVLMDCGVDLTASCNSEPKELAGDPEAVP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KEELPRESFKEVLENQETFLDLNVQPGHSNPEVLMDCGVDLTASCNSEPKELAGDPEAVP
1150 1160 1170 1180 1190 1200
1510 1520 1530 1540 1550 1560
pF1KE2 ESDEEPPPGEQAQKQDQKNSKEVDTEFKEGNPATMEIDSETVQAVQSLTQESSEQDDTFQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ESDEEPPPGEQAQKQDQKNSKEVDTEFKEGNPATMEIDSETVQAVQSLTQESSEQDDTFQ
1210 1220 1230 1240 1250 1260
1570 1580 1590 1600 1610 1620
pF1KE2 DCAETQEACRSLQNYTRADQSPQIATTLDDCQQSDHSSPVSSVHSHPGQSVRSVNSPSVP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DCAETQEACRSLQNYTRADQSPQIATTLDDCQQSDHSSPVSSVHSHPGQSVRSVNSPSVP
1270 1280 1290 1300 1310 1320
1630 1640 1650 1660 1670 1680
pF1KE2 ALENSYAQISPDQSAISVPSLQNMETSPMMDVPSVSDHSQQVVDSGFSDLGSIESTTENY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ALENSYAQISPDQSAISVPSLQNMETSPMMDVPSVSDHSQQVVDSGFSDLGSIESTTENY
1330 1340 1350 1360 1370 1380
1690 1700 1710 1720 1730 1740
pF1KE2 ENPSSYDSTMGGSICGNGSSQNSCSYSNLTSSSLTQSSCAVTQQMSNISGSCSMLQQTSI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ENPSSYDSTMGGSICGNGSSQNSCSYSNLTSSSLTQSSCAVTQQMSNISGSCSMLQQTSI
1390 1400 1410 1420 1430 1440
1750 1760 1770 1780 1790 1800
pF1KE2 SSPPTCSVKSPQGCVVERPPSSSQQLAQCSMAANFTPPMQLAEIPETSNANIGLYERMGQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SSPPTCSVKSPQGCVVERPPSSSQQLAQCSMAANFTPPMQLAEIPETSNANIGLYERMGQ
1450 1460 1470 1480 1490 1500
1810 1820 1830 1840 1850 1860
pF1KE2 SDFGAGHYPQPSATFSLAKLQQLTNTLIDHSLPYSHSAAVTSYANSASLSTPLSNTGLVQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SDFGAGHYPQPSATFSLAKLQQLTNTLIDHSLPYSHSAAVTSYANSASLSTPLSNTGLVQ
1510 1520 1530 1540 1550 1560
1870 1880 1890 1900 1910 1920
pF1KE2 LSQSPHSVPGGPQAQATMTPPPNLTPPPMNLPPPLLQRNMAASNIGISHSQRLQTQIASK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LSQSPHSVPGGPQAQATMTPPPNLTPPPMNLPPPLLQRNMAASNIGISHSQRLQTQIASK
1570 1580 1590 1600 1610 1620
1930 1940 1950 1960 1970 1980
pF1KE2 GHISMRTKSASLSPAAATHQSQIYGRSQTVAMQGPARTLTMQRGMNMSVNLMPAPAYNVN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GHISMRTKSASLSPAAATHQSQIYGRSQTVAMQGPARTLTMQRGMNMSVNLMPAPAYNVN
1630 1640 1650 1660 1670 1680
1990 2000 2010 2020 2030 2040
pF1KE2 SVNMNMNTLNAMNGYSMSQPMMNSGYHSNHGYMNQTPQYPMQMQMGMMGTQPYAQQPMQT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SVNMNMNTLNAMNGYSMSQPMMNSGYHSNHGYMNQTPQYPMQMQMGMMGTQPYAQQPMQT
1690 1700 1710 1720 1730 1740
2050 2060 2070
pF1KE2 PPHGNMMYTAPGHHGYMNTGMSKQSLNGSYMRR
:::::::::::::::::::::::::::::::::
XP_016 PPHGNMMYTAPGHHGYMNTGMSKQSLNGSYMRR
1750 1760 1770 1780
>>XP_016871495 (OMIM: 603736,605880,606170) PREDICTED: h (1781 aa)
initn: 9460 init1: 9460 opt: 9491 Z-score: 4264.1 bits: 802.4 E(85289): 0
Smith-Waterman score: 11450; 85.9% identity (85.9% similar) in 2073 aa overlap (1-2073:1-1781)
10 20 30 40 50 60
pF1KE2 MVKLANPLYTEWILEAIQKIKKQKQRPSEERICHAVSTSHGLDKKTVSEQLELSVQDGSV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MVKLANPLYTEWILEAIQKIKKQKQRPSEERICHAVSTSHGLDKKTVSEQLELSVQDGSV
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE2 LKVTNKGLASYKDPDNPGRFSSVKPGTFPKSAKGSRGSCNDLRNVDWNKLLRRAIEGLEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LKVTNKGLASYKDPDNPGRFSSVKPGTFPKSAKGSRGSCNDLRNVDWNKLLRRAIEGLEE
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE2 PNGSSLKNIEKYLRSQSDLTSTTNNPAFQQRLRLGAKRAVNNGRLLKDGPQYRVNYGSLD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PNGSSLKNIEKYLRSQSDLTSTTNNPAFQQRLRLGAKRAVNNGRLLKDGPQYRVNYGSLD
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE2 GKGAPQYPSAFPSSLPPVSLLPHEKDQPRADPIPICSFCLGTKESNREKKPEELLSCADC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GKGAPQYPSAFPSSLPPVSLLPHEKDQPRADPIPICSFCLGTKESNREKKPEELLSCADC
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE2 GSSGHPSCLKFCPELTTNVKALRWQCIECKTCSACRVQGRNADNMLFCDSCDRGFHMECC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GSSGHPSCLKFCPELTTNVKALRWQCIECKTCSACRVQGRNADNMLFCDSCDRGFHMECC
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE2 DPPLSRMPKGMWICQVCRPKKKGRKLLHEKAAQIKRRYAKPIGRPKNKLKQRLLSVTSDE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DPPLSRMPKGMWICQVCRPKKKGRKLLHEKAAQIKRRYAKPIGRPKNKLKQRLLSVTSDE
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE2 GSMNAFTGRGSPGRGQKTKVCTTPSSGHAASGKDSSSRLAVTDPTRPGATTKITTTSTYI
::::::::::::
XP_016 GSMNAFTGRGSP------------------------------------------------
370
430 440 450 460 470 480
pF1KE2 SASTLKVNKKTKGLIDGLTKFFTPSPDGRRSRGEIIDFSKHYRPRKKVSQKQSCTSHVLA
XP_016 ------------------------------------------------------------
490 500 510 520 530 540
pF1KE2 TGTTQKLKPPPSSLPPPTPISGQSPSSQKSSTATSSPSPQSSSSQCSVPSLSSLTTNSQL
XP_016 ------------------------------------------------------------
550 560 570 580 590 600
pF1KE2 KALFDGLSHIYTTQGQSRKKGHPSYAPPKRMRRKTELSSTAKSKAHFFGKRDIRSRFISH
XP_016 ------------------------------------------------------------
610 620 630 640 650 660
pF1KE2 SSSSSWGMARGSIFKAIAHFKRTTFLKKHRMLGRLKYKVTPQMGTPSPGKGSLTDGRIKP
XP_016 ------------------------------------------------------------
670 680 690 700 710 720
pF1KE2 DQDDDTEIKINIKQESADVNVIGNKDVVTEEDLDVFKQAQELSWEKIECESGVEDCGRYP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ----DTEIKINIKQESADVNVIGNKDVVTEEDLDVFKQAQELSWEKIECESGVEDCGRYP
380 390 400 410 420
730 740 750 760 770 780
pF1KE2 SVIEFGKYEIQTWYSSPYPQEYARLPKLYLCEFCLKYMKSKNILLRHSKKCGWFHPPANE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SVIEFGKYEIQTWYSSPYPQEYARLPKLYLCEFCLKYMKSKNILLRHSKKCGWFHPPANE
430 440 450 460 470 480
790 800 810 820 830 840
pF1KE2 IYRRKDLSVFEVDGNMSKIYCQNLCLLAKLFLDHKTLYYDVEPFLFYVLTKNDEKGCHLV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IYRRKDLSVFEVDGNMSKIYCQNLCLLAKLFLDHKTLYYDVEPFLFYVLTKNDEKGCHLV
490 500 510 520 530 540
850 860 870 880 890 900
pF1KE2 GYFSKEKLCQQKYNVSCIMIMPQHQRQGFGRFLIDFSYLLSRREGQAGSPEKPLSDLGRL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GYFSKEKLCQQKYNVSCIMIMPQHQRQGFGRFLIDFSYLLSRREGQAGSPEKPLSDLGRL
550 560 570 580 590 600
910 920 930 940 950 960
pF1KE2 SYLAYWKSVILEYLYHHHERHISIKAISRATGMCPHDIATTLQHLHMIDKRDGRFVIIRR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SYLAYWKSVILEYLYHHHERHISIKAISRATGMCPHDIATTLQHLHMIDKRDGRFVIIRR
610 620 630 640 650 660
970 980 990 1000 1010 1020
pF1KE2 EKLILSHMEKLKTCSRANELDPDSLRWTPILISNAAVSEEEREAEKEAERLMEQASCWEK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EKLILSHMEKLKTCSRANELDPDSLRWTPILISNAAVSEEEREAEKEAERLMEQASCWEK
670 680 690 700 710 720
1030 1040 1050 1060 1070 1080
pF1KE2 EEQEILSTRANSRQSPAKVQSKNKYLHSPESRPVTGERGQLLELSKESSEEEEEEEDEEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EEQEILSTRANSRQSPAKVQSKNKYLHSPESRPVTGERGQLLELSKESSEEEEEEEDEEE
730 740 750 760 770 780
1090 1100 1110 1120 1130 1140
pF1KE2 EEEEEEEEEDEEEEEEEEEEEEEENIQSSPPRLTKPQSVAIKRKRPFVLKKKRGRKRRRI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EEEEEEEEEDEEEEEEEEEEEEEENIQSSPPRLTKPQSVAIKRKRPFVLKKKRGRKRRRI
790 800 810 820 830 840
1150 1160 1170 1180 1190 1200
pF1KE2 NSSVTTETISETTEVLNEPFDNSDEERPMPQLEPTCEIEVEEDGRKPVLRKAFQHQPGKK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NSSVTTETISETTEVLNEPFDNSDEERPMPQLEPTCEIEVEEDGRKPVLRKAFQHQPGKK
850 860 870 880 890 900
1210 1220 1230 1240 1250 1260
pF1KE2 RQTEEEEGKDNHCFKNADPCRNNMNDDSSNLKEGSKDNPEPLKCKQVWPKGTKRGLSKWR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RQTEEEEGKDNHCFKNADPCRNNMNDDSSNLKEGSKDNPEPLKCKQVWPKGTKRGLSKWR
910 920 930 940 950 960
1270 1280 1290 1300 1310 1320
pF1KE2 QNKERKTGFKLNLYTPPETPMEPDEQVTVEEQKETSEGKTSPSPIRIEEEVKETGEALLP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QNKERKTGFKLNLYTPPETPMEPDEQVTVEEQKETSEGKTSPSPIRIEEEVKETGEALLP
970 980 990 1000 1010 1020
1330 1340 1350 1360 1370 1380
pF1KE2 QEENRREETCAPVSPNTSPGEKPEDDLIKPEEEEEEEEEEEEEEEEEEGEEEEGGGNVEK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QEENRREETCAPVSPNTSPGEKPEDDLIKPEEEEEEEEEEEEEEEEEEGEEEEGGGNVEK
1030 1040 1050 1060 1070 1080
1390 1400 1410 1420 1430 1440
pF1KE2 DPDGAKSQEKEEPEISTEKEDSARLDDHEEEEEEDEEPSHNEDHDADDEDDSHMESAEVE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DPDGAKSQEKEEPEISTEKEDSARLDDHEEEEEEDEEPSHNEDHDADDEDDSHMESAEVE
1090 1100 1110 1120 1130 1140
1450 1460 1470 1480 1490 1500
pF1KE2 KEELPRESFKEVLENQETFLDLNVQPGHSNPEVLMDCGVDLTASCNSEPKELAGDPEAVP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KEELPRESFKEVLENQETFLDLNVQPGHSNPEVLMDCGVDLTASCNSEPKELAGDPEAVP
1150 1160 1170 1180 1190 1200
1510 1520 1530 1540 1550 1560
pF1KE2 ESDEEPPPGEQAQKQDQKNSKEVDTEFKEGNPATMEIDSETVQAVQSLTQESSEQDDTFQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ESDEEPPPGEQAQKQDQKNSKEVDTEFKEGNPATMEIDSETVQAVQSLTQESSEQDDTFQ
1210 1220 1230 1240 1250 1260
1570 1580 1590 1600 1610 1620
pF1KE2 DCAETQEACRSLQNYTRADQSPQIATTLDDCQQSDHSSPVSSVHSHPGQSVRSVNSPSVP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DCAETQEACRSLQNYTRADQSPQIATTLDDCQQSDHSSPVSSVHSHPGQSVRSVNSPSVP
1270 1280 1290 1300 1310 1320
1630 1640 1650 1660 1670 1680
pF1KE2 ALENSYAQISPDQSAISVPSLQNMETSPMMDVPSVSDHSQQVVDSGFSDLGSIESTTENY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ALENSYAQISPDQSAISVPSLQNMETSPMMDVPSVSDHSQQVVDSGFSDLGSIESTTENY
1330 1340 1350 1360 1370 1380
1690 1700 1710 1720 1730 1740
pF1KE2 ENPSSYDSTMGGSICGNGSSQNSCSYSNLTSSSLTQSSCAVTQQMSNISGSCSMLQQTSI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ENPSSYDSTMGGSICGNGSSQNSCSYSNLTSSSLTQSSCAVTQQMSNISGSCSMLQQTSI
1390 1400 1410 1420 1430 1440
1750 1760 1770 1780 1790 1800
pF1KE2 SSPPTCSVKSPQGCVVERPPSSSQQLAQCSMAANFTPPMQLAEIPETSNANIGLYERMGQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SSPPTCSVKSPQGCVVERPPSSSQQLAQCSMAANFTPPMQLAEIPETSNANIGLYERMGQ
1450 1460 1470 1480 1490 1500
1810 1820 1830 1840 1850 1860
pF1KE2 SDFGAGHYPQPSATFSLAKLQQLTNTLIDHSLPYSHSAAVTSYANSASLSTPLSNTGLVQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SDFGAGHYPQPSATFSLAKLQQLTNTLIDHSLPYSHSAAVTSYANSASLSTPLSNTGLVQ
1510 1520 1530 1540 1550 1560
1870 1880 1890 1900 1910 1920
pF1KE2 LSQSPHSVPGGPQAQATMTPPPNLTPPPMNLPPPLLQRNMAASNIGISHSQRLQTQIASK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LSQSPHSVPGGPQAQATMTPPPNLTPPPMNLPPPLLQRNMAASNIGISHSQRLQTQIASK
1570 1580 1590 1600 1610 1620
1930 1940 1950 1960 1970 1980
pF1KE2 GHISMRTKSASLSPAAATHQSQIYGRSQTVAMQGPARTLTMQRGMNMSVNLMPAPAYNVN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GHISMRTKSASLSPAAATHQSQIYGRSQTVAMQGPARTLTMQRGMNMSVNLMPAPAYNVN
1630 1640 1650 1660 1670 1680
1990 2000 2010 2020 2030 2040
pF1KE2 SVNMNMNTLNAMNGYSMSQPMMNSGYHSNHGYMNQTPQYPMQMQMGMMGTQPYAQQPMQT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SVNMNMNTLNAMNGYSMSQPMMNSGYHSNHGYMNQTPQYPMQMQMGMMGTQPYAQQPMQT
1690 1700 1710 1720 1730 1740
2050 2060 2070
pF1KE2 PPHGNMMYTAPGHHGYMNTGMSKQSLNGSYMRR
:::::::::::::::::::::::::::::::::
XP_016 PPHGNMMYTAPGHHGYMNTGMSKQSLNGSYMRR
1750 1760 1770 1780
>>XP_016871497 (OMIM: 603736,605880,606170) PREDICTED: h (1781 aa)
initn: 9460 init1: 9460 opt: 9491 Z-score: 4264.1 bits: 802.4 E(85289): 0
Smith-Waterman score: 11450; 85.9% identity (85.9% similar) in 2073 aa overlap (1-2073:1-1781)
10 20 30 40 50 60
pF1KE2 MVKLANPLYTEWILEAIQKIKKQKQRPSEERICHAVSTSHGLDKKTVSEQLELSVQDGSV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MVKLANPLYTEWILEAIQKIKKQKQRPSEERICHAVSTSHGLDKKTVSEQLELSVQDGSV
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE2 LKVTNKGLASYKDPDNPGRFSSVKPGTFPKSAKGSRGSCNDLRNVDWNKLLRRAIEGLEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LKVTNKGLASYKDPDNPGRFSSVKPGTFPKSAKGSRGSCNDLRNVDWNKLLRRAIEGLEE
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE2 PNGSSLKNIEKYLRSQSDLTSTTNNPAFQQRLRLGAKRAVNNGRLLKDGPQYRVNYGSLD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PNGSSLKNIEKYLRSQSDLTSTTNNPAFQQRLRLGAKRAVNNGRLLKDGPQYRVNYGSLD
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE2 GKGAPQYPSAFPSSLPPVSLLPHEKDQPRADPIPICSFCLGTKESNREKKPEELLSCADC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GKGAPQYPSAFPSSLPPVSLLPHEKDQPRADPIPICSFCLGTKESNREKKPEELLSCADC
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE2 GSSGHPSCLKFCPELTTNVKALRWQCIECKTCSACRVQGRNADNMLFCDSCDRGFHMECC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GSSGHPSCLKFCPELTTNVKALRWQCIECKTCSACRVQGRNADNMLFCDSCDRGFHMECC
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE2 DPPLSRMPKGMWICQVCRPKKKGRKLLHEKAAQIKRRYAKPIGRPKNKLKQRLLSVTSDE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DPPLSRMPKGMWICQVCRPKKKGRKLLHEKAAQIKRRYAKPIGRPKNKLKQRLLSVTSDE
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE2 GSMNAFTGRGSPGRGQKTKVCTTPSSGHAASGKDSSSRLAVTDPTRPGATTKITTTSTYI
::::::::::::
XP_016 GSMNAFTGRGSP------------------------------------------------
370
430 440 450 460 470 480
pF1KE2 SASTLKVNKKTKGLIDGLTKFFTPSPDGRRSRGEIIDFSKHYRPRKKVSQKQSCTSHVLA
XP_016 ------------------------------------------------------------
490 500 510 520 530 540
pF1KE2 TGTTQKLKPPPSSLPPPTPISGQSPSSQKSSTATSSPSPQSSSSQCSVPSLSSLTTNSQL
XP_016 ------------------------------------------------------------
550 560 570 580 590 600
pF1KE2 KALFDGLSHIYTTQGQSRKKGHPSYAPPKRMRRKTELSSTAKSKAHFFGKRDIRSRFISH
XP_016 ------------------------------------------------------------
610 620 630 640 650 660
pF1KE2 SSSSSWGMARGSIFKAIAHFKRTTFLKKHRMLGRLKYKVTPQMGTPSPGKGSLTDGRIKP
XP_016 ------------------------------------------------------------
670 680 690 700 710 720
pF1KE2 DQDDDTEIKINIKQESADVNVIGNKDVVTEEDLDVFKQAQELSWEKIECESGVEDCGRYP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ----DTEIKINIKQESADVNVIGNKDVVTEEDLDVFKQAQELSWEKIECESGVEDCGRYP
380 390 400 410 420
730 740 750 760 770 780
pF1KE2 SVIEFGKYEIQTWYSSPYPQEYARLPKLYLCEFCLKYMKSKNILLRHSKKCGWFHPPANE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SVIEFGKYEIQTWYSSPYPQEYARLPKLYLCEFCLKYMKSKNILLRHSKKCGWFHPPANE
430 440 450 460 470 480
790 800 810 820 830 840
pF1KE2 IYRRKDLSVFEVDGNMSKIYCQNLCLLAKLFLDHKTLYYDVEPFLFYVLTKNDEKGCHLV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IYRRKDLSVFEVDGNMSKIYCQNLCLLAKLFLDHKTLYYDVEPFLFYVLTKNDEKGCHLV
490 500 510 520 530 540
850 860 870 880 890 900
pF1KE2 GYFSKEKLCQQKYNVSCIMIMPQHQRQGFGRFLIDFSYLLSRREGQAGSPEKPLSDLGRL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GYFSKEKLCQQKYNVSCIMIMPQHQRQGFGRFLIDFSYLLSRREGQAGSPEKPLSDLGRL
550 560 570 580 590 600
910 920 930 940 950 960
pF1KE2 SYLAYWKSVILEYLYHHHERHISIKAISRATGMCPHDIATTLQHLHMIDKRDGRFVIIRR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SYLAYWKSVILEYLYHHHERHISIKAISRATGMCPHDIATTLQHLHMIDKRDGRFVIIRR
610 620 630 640 650 660
970 980 990 1000 1010 1020
pF1KE2 EKLILSHMEKLKTCSRANELDPDSLRWTPILISNAAVSEEEREAEKEAERLMEQASCWEK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EKLILSHMEKLKTCSRANELDPDSLRWTPILISNAAVSEEEREAEKEAERLMEQASCWEK
670 680 690 700 710 720
1030 1040 1050 1060 1070 1080
pF1KE2 EEQEILSTRANSRQSPAKVQSKNKYLHSPESRPVTGERGQLLELSKESSEEEEEEEDEEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EEQEILSTRANSRQSPAKVQSKNKYLHSPESRPVTGERGQLLELSKESSEEEEEEEDEEE
730 740 750 760 770 780
1090 1100 1110 1120 1130 1140
pF1KE2 EEEEEEEEEDEEEEEEEEEEEEEENIQSSPPRLTKPQSVAIKRKRPFVLKKKRGRKRRRI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EEEEEEEEEDEEEEEEEEEEEEEENIQSSPPRLTKPQSVAIKRKRPFVLKKKRGRKRRRI
790 800 810 820 830 840
1150 1160 1170 1180 1190 1200
pF1KE2 NSSVTTETISETTEVLNEPFDNSDEERPMPQLEPTCEIEVEEDGRKPVLRKAFQHQPGKK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NSSVTTETISETTEVLNEPFDNSDEERPMPQLEPTCEIEVEEDGRKPVLRKAFQHQPGKK
850 860 870 880 890 900
1210 1220 1230 1240 1250 1260
pF1KE2 RQTEEEEGKDNHCFKNADPCRNNMNDDSSNLKEGSKDNPEPLKCKQVWPKGTKRGLSKWR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RQTEEEEGKDNHCFKNADPCRNNMNDDSSNLKEGSKDNPEPLKCKQVWPKGTKRGLSKWR
910 920 930 940 950 960
1270 1280 1290 1300 1310 1320
pF1KE2 QNKERKTGFKLNLYTPPETPMEPDEQVTVEEQKETSEGKTSPSPIRIEEEVKETGEALLP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QNKERKTGFKLNLYTPPETPMEPDEQVTVEEQKETSEGKTSPSPIRIEEEVKETGEALLP
970 980 990 1000 1010 1020
1330 1340 1350 1360 1370 1380
pF1KE2 QEENRREETCAPVSPNTSPGEKPEDDLIKPEEEEEEEEEEEEEEEEEEGEEEEGGGNVEK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QEENRREETCAPVSPNTSPGEKPEDDLIKPEEEEEEEEEEEEEEEEEEGEEEEGGGNVEK
1030 1040 1050 1060 1070 1080
1390 1400 1410 1420 1430 1440
pF1KE2 DPDGAKSQEKEEPEISTEKEDSARLDDHEEEEEEDEEPSHNEDHDADDEDDSHMESAEVE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DPDGAKSQEKEEPEISTEKEDSARLDDHEEEEEEDEEPSHNEDHDADDEDDSHMESAEVE
1090 1100 1110 1120 1130 1140
1450 1460 1470 1480 1490 1500
pF1KE2 KEELPRESFKEVLENQETFLDLNVQPGHSNPEVLMDCGVDLTASCNSEPKELAGDPEAVP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KEELPRESFKEVLENQETFLDLNVQPGHSNPEVLMDCGVDLTASCNSEPKELAGDPEAVP
1150 1160 1170 1180 1190 1200
1510 1520 1530 1540 1550 1560
pF1KE2 ESDEEPPPGEQAQKQDQKNSKEVDTEFKEGNPATMEIDSETVQAVQSLTQESSEQDDTFQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ESDEEPPPGEQAQKQDQKNSKEVDTEFKEGNPATMEIDSETVQAVQSLTQESSEQDDTFQ
1210 1220 1230 1240 1250 1260
1570 1580 1590 1600 1610 1620
pF1KE2 DCAETQEACRSLQNYTRADQSPQIATTLDDCQQSDHSSPVSSVHSHPGQSVRSVNSPSVP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DCAETQEACRSLQNYTRADQSPQIATTLDDCQQSDHSSPVSSVHSHPGQSVRSVNSPSVP
1270 1280 1290 1300 1310 1320
1630 1640 1650 1660 1670 1680
pF1KE2 ALENSYAQISPDQSAISVPSLQNMETSPMMDVPSVSDHSQQVVDSGFSDLGSIESTTENY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ALENSYAQISPDQSAISVPSLQNMETSPMMDVPSVSDHSQQVVDSGFSDLGSIESTTENY
1330 1340 1350 1360 1370 1380
1690 1700 1710 1720 1730 1740
pF1KE2 ENPSSYDSTMGGSICGNGSSQNSCSYSNLTSSSLTQSSCAVTQQMSNISGSCSMLQQTSI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ENPSSYDSTMGGSICGNGSSQNSCSYSNLTSSSLTQSSCAVTQQMSNISGSCSMLQQTSI
1390 1400 1410 1420 1430 1440
1750 1760 1770 1780 1790 1800
pF1KE2 SSPPTCSVKSPQGCVVERPPSSSQQLAQCSMAANFTPPMQLAEIPETSNANIGLYERMGQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SSPPTCSVKSPQGCVVERPPSSSQQLAQCSMAANFTPPMQLAEIPETSNANIGLYERMGQ
1450 1460 1470 1480 1490 1500
1810 1820 1830 1840 1850 1860
pF1KE2 SDFGAGHYPQPSATFSLAKLQQLTNTLIDHSLPYSHSAAVTSYANSASLSTPLSNTGLVQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SDFGAGHYPQPSATFSLAKLQQLTNTLIDHSLPYSHSAAVTSYANSASLSTPLSNTGLVQ
1510 1520 1530 1540 1550 1560
1870 1880 1890 1900 1910 1920
pF1KE2 LSQSPHSVPGGPQAQATMTPPPNLTPPPMNLPPPLLQRNMAASNIGISHSQRLQTQIASK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LSQSPHSVPGGPQAQATMTPPPNLTPPPMNLPPPLLQRNMAASNIGISHSQRLQTQIASK
1570 1580 1590 1600 1610 1620
1930 1940 1950 1960 1970 1980
pF1KE2 GHISMRTKSASLSPAAATHQSQIYGRSQTVAMQGPARTLTMQRGMNMSVNLMPAPAYNVN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GHISMRTKSASLSPAAATHQSQIYGRSQTVAMQGPARTLTMQRGMNMSVNLMPAPAYNVN
1630 1640 1650 1660 1670 1680
1990 2000 2010 2020 2030 2040
pF1KE2 SVNMNMNTLNAMNGYSMSQPMMNSGYHSNHGYMNQTPQYPMQMQMGMMGTQPYAQQPMQT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SVNMNMNTLNAMNGYSMSQPMMNSGYHSNHGYMNQTPQYPMQMQMGMMGTQPYAQQPMQT
1690 1700 1710 1720 1730 1740
2050 2060 2070
pF1KE2 PPHGNMMYTAPGHHGYMNTGMSKQSLNGSYMRR
:::::::::::::::::::::::::::::::::
XP_016 PPHGNMMYTAPGHHGYMNTGMSKQSLNGSYMRR
1750 1760 1770 1780
>>NP_001243398 (OMIM: 603736,605880,606170) histone acet (1781 aa)
initn: 9460 init1: 9460 opt: 9491 Z-score: 4264.1 bits: 802.4 E(85289): 0
Smith-Waterman score: 11450; 85.9% identity (85.9% similar) in 2073 aa overlap (1-2073:1-1781)
10 20 30 40 50 60
pF1KE2 MVKLANPLYTEWILEAIQKIKKQKQRPSEERICHAVSTSHGLDKKTVSEQLELSVQDGSV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MVKLANPLYTEWILEAIQKIKKQKQRPSEERICHAVSTSHGLDKKTVSEQLELSVQDGSV
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE2 LKVTNKGLASYKDPDNPGRFSSVKPGTFPKSAKGSRGSCNDLRNVDWNKLLRRAIEGLEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LKVTNKGLASYKDPDNPGRFSSVKPGTFPKSAKGSRGSCNDLRNVDWNKLLRRAIEGLEE
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE2 PNGSSLKNIEKYLRSQSDLTSTTNNPAFQQRLRLGAKRAVNNGRLLKDGPQYRVNYGSLD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PNGSSLKNIEKYLRSQSDLTSTTNNPAFQQRLRLGAKRAVNNGRLLKDGPQYRVNYGSLD
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE2 GKGAPQYPSAFPSSLPPVSLLPHEKDQPRADPIPICSFCLGTKESNREKKPEELLSCADC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GKGAPQYPSAFPSSLPPVSLLPHEKDQPRADPIPICSFCLGTKESNREKKPEELLSCADC
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE2 GSSGHPSCLKFCPELTTNVKALRWQCIECKTCSACRVQGRNADNMLFCDSCDRGFHMECC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GSSGHPSCLKFCPELTTNVKALRWQCIECKTCSACRVQGRNADNMLFCDSCDRGFHMECC
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE2 DPPLSRMPKGMWICQVCRPKKKGRKLLHEKAAQIKRRYAKPIGRPKNKLKQRLLSVTSDE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DPPLSRMPKGMWICQVCRPKKKGRKLLHEKAAQIKRRYAKPIGRPKNKLKQRLLSVTSDE
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE2 GSMNAFTGRGSPGRGQKTKVCTTPSSGHAASGKDSSSRLAVTDPTRPGATTKITTTSTYI
::::::::::::
NP_001 GSMNAFTGRGSP------------------------------------------------
370
430 440 450 460 470 480
pF1KE2 SASTLKVNKKTKGLIDGLTKFFTPSPDGRRSRGEIIDFSKHYRPRKKVSQKQSCTSHVLA
NP_001 ------------------------------------------------------------
490 500 510 520 530 540
pF1KE2 TGTTQKLKPPPSSLPPPTPISGQSPSSQKSSTATSSPSPQSSSSQCSVPSLSSLTTNSQL
NP_001 ------------------------------------------------------------
550 560 570 580 590 600
pF1KE2 KALFDGLSHIYTTQGQSRKKGHPSYAPPKRMRRKTELSSTAKSKAHFFGKRDIRSRFISH
NP_001 ------------------------------------------------------------
610 620 630 640 650 660
pF1KE2 SSSSSWGMARGSIFKAIAHFKRTTFLKKHRMLGRLKYKVTPQMGTPSPGKGSLTDGRIKP
NP_001 ------------------------------------------------------------
670 680 690 700 710 720
pF1KE2 DQDDDTEIKINIKQESADVNVIGNKDVVTEEDLDVFKQAQELSWEKIECESGVEDCGRYP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ----DTEIKINIKQESADVNVIGNKDVVTEEDLDVFKQAQELSWEKIECESGVEDCGRYP
380 390 400 410 420
730 740 750 760 770 780
pF1KE2 SVIEFGKYEIQTWYSSPYPQEYARLPKLYLCEFCLKYMKSKNILLRHSKKCGWFHPPANE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SVIEFGKYEIQTWYSSPYPQEYARLPKLYLCEFCLKYMKSKNILLRHSKKCGWFHPPANE
430 440 450 460 470 480
790 800 810 820 830 840
pF1KE2 IYRRKDLSVFEVDGNMSKIYCQNLCLLAKLFLDHKTLYYDVEPFLFYVLTKNDEKGCHLV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IYRRKDLSVFEVDGNMSKIYCQNLCLLAKLFLDHKTLYYDVEPFLFYVLTKNDEKGCHLV
490 500 510 520 530 540
850 860 870 880 890 900
pF1KE2 GYFSKEKLCQQKYNVSCIMIMPQHQRQGFGRFLIDFSYLLSRREGQAGSPEKPLSDLGRL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GYFSKEKLCQQKYNVSCIMIMPQHQRQGFGRFLIDFSYLLSRREGQAGSPEKPLSDLGRL
550 560 570 580 590 600
910 920 930 940 950 960
pF1KE2 SYLAYWKSVILEYLYHHHERHISIKAISRATGMCPHDIATTLQHLHMIDKRDGRFVIIRR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SYLAYWKSVILEYLYHHHERHISIKAISRATGMCPHDIATTLQHLHMIDKRDGRFVIIRR
610 620 630 640 650 660
970 980 990 1000 1010 1020
pF1KE2 EKLILSHMEKLKTCSRANELDPDSLRWTPILISNAAVSEEEREAEKEAERLMEQASCWEK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EKLILSHMEKLKTCSRANELDPDSLRWTPILISNAAVSEEEREAEKEAERLMEQASCWEK
670 680 690 700 710 720
1030 1040 1050 1060 1070 1080
pF1KE2 EEQEILSTRANSRQSPAKVQSKNKYLHSPESRPVTGERGQLLELSKESSEEEEEEEDEEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EEQEILSTRANSRQSPAKVQSKNKYLHSPESRPVTGERGQLLELSKESSEEEEEEEDEEE
730 740 750 760 770 780
1090 1100 1110 1120 1130 1140
pF1KE2 EEEEEEEEEDEEEEEEEEEEEEEENIQSSPPRLTKPQSVAIKRKRPFVLKKKRGRKRRRI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EEEEEEEEEDEEEEEEEEEEEEEENIQSSPPRLTKPQSVAIKRKRPFVLKKKRGRKRRRI
790 800 810 820 830 840
1150 1160 1170 1180 1190 1200
pF1KE2 NSSVTTETISETTEVLNEPFDNSDEERPMPQLEPTCEIEVEEDGRKPVLRKAFQHQPGKK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NSSVTTETISETTEVLNEPFDNSDEERPMPQLEPTCEIEVEEDGRKPVLRKAFQHQPGKK
850 860 870 880 890 900
1210 1220 1230 1240 1250 1260
pF1KE2 RQTEEEEGKDNHCFKNADPCRNNMNDDSSNLKEGSKDNPEPLKCKQVWPKGTKRGLSKWR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RQTEEEEGKDNHCFKNADPCRNNMNDDSSNLKEGSKDNPEPLKCKQVWPKGTKRGLSKWR
910 920 930 940 950 960
1270 1280 1290 1300 1310 1320
pF1KE2 QNKERKTGFKLNLYTPPETPMEPDEQVTVEEQKETSEGKTSPSPIRIEEEVKETGEALLP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QNKERKTGFKLNLYTPPETPMEPDEQVTVEEQKETSEGKTSPSPIRIEEEVKETGEALLP
970 980 990 1000 1010 1020
1330 1340 1350 1360 1370 1380
pF1KE2 QEENRREETCAPVSPNTSPGEKPEDDLIKPEEEEEEEEEEEEEEEEEEGEEEEGGGNVEK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QEENRREETCAPVSPNTSPGEKPEDDLIKPEEEEEEEEEEEEEEEEEEGEEEEGGGNVEK
1030 1040 1050 1060 1070 1080
1390 1400 1410 1420 1430 1440
pF1KE2 DPDGAKSQEKEEPEISTEKEDSARLDDHEEEEEEDEEPSHNEDHDADDEDDSHMESAEVE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DPDGAKSQEKEEPEISTEKEDSARLDDHEEEEEEDEEPSHNEDHDADDEDDSHMESAEVE
1090 1100 1110 1120 1130 1140
1450 1460 1470 1480 1490 1500
pF1KE2 KEELPRESFKEVLENQETFLDLNVQPGHSNPEVLMDCGVDLTASCNSEPKELAGDPEAVP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KEELPRESFKEVLENQETFLDLNVQPGHSNPEVLMDCGVDLTASCNSEPKELAGDPEAVP
1150 1160 1170 1180 1190 1200
1510 1520 1530 1540 1550 1560
pF1KE2 ESDEEPPPGEQAQKQDQKNSKEVDTEFKEGNPATMEIDSETVQAVQSLTQESSEQDDTFQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ESDEEPPPGEQAQKQDQKNSKEVDTEFKEGNPATMEIDSETVQAVQSLTQESSEQDDTFQ
1210 1220 1230 1240 1250 1260
1570 1580 1590 1600 1610 1620
pF1KE2 DCAETQEACRSLQNYTRADQSPQIATTLDDCQQSDHSSPVSSVHSHPGQSVRSVNSPSVP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DCAETQEACRSLQNYTRADQSPQIATTLDDCQQSDHSSPVSSVHSHPGQSVRSVNSPSVP
1270 1280 1290 1300 1310 1320
1630 1640 1650 1660 1670 1680
pF1KE2 ALENSYAQISPDQSAISVPSLQNMETSPMMDVPSVSDHSQQVVDSGFSDLGSIESTTENY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ALENSYAQISPDQSAISVPSLQNMETSPMMDVPSVSDHSQQVVDSGFSDLGSIESTTENY
1330 1340 1350 1360 1370 1380
1690 1700 1710 1720 1730 1740
pF1KE2 ENPSSYDSTMGGSICGNGSSQNSCSYSNLTSSSLTQSSCAVTQQMSNISGSCSMLQQTSI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ENPSSYDSTMGGSICGNGSSQNSCSYSNLTSSSLTQSSCAVTQQMSNISGSCSMLQQTSI
1390 1400 1410 1420 1430 1440
1750 1760 1770 1780 1790 1800
pF1KE2 SSPPTCSVKSPQGCVVERPPSSSQQLAQCSMAANFTPPMQLAEIPETSNANIGLYERMGQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SSPPTCSVKSPQGCVVERPPSSSQQLAQCSMAANFTPPMQLAEIPETSNANIGLYERMGQ
1450 1460 1470 1480 1490 1500
1810 1820 1830 1840 1850 1860
pF1KE2 SDFGAGHYPQPSATFSLAKLQQLTNTLIDHSLPYSHSAAVTSYANSASLSTPLSNTGLVQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SDFGAGHYPQPSATFSLAKLQQLTNTLIDHSLPYSHSAAVTSYANSASLSTPLSNTGLVQ
1510 1520 1530 1540 1550 1560
1870 1880 1890 1900 1910 1920
pF1KE2 LSQSPHSVPGGPQAQATMTPPPNLTPPPMNLPPPLLQRNMAASNIGISHSQRLQTQIASK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LSQSPHSVPGGPQAQATMTPPPNLTPPPMNLPPPLLQRNMAASNIGISHSQRLQTQIASK
1570 1580 1590 1600 1610 1620
1930 1940 1950 1960 1970 1980
pF1KE2 GHISMRTKSASLSPAAATHQSQIYGRSQTVAMQGPARTLTMQRGMNMSVNLMPAPAYNVN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GHISMRTKSASLSPAAATHQSQIYGRSQTVAMQGPARTLTMQRGMNMSVNLMPAPAYNVN
1630 1640 1650 1660 1670 1680
1990 2000 2010 2020 2030 2040
pF1KE2 SVNMNMNTLNAMNGYSMSQPMMNSGYHSNHGYMNQTPQYPMQMQMGMMGTQPYAQQPMQT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SVNMNMNTLNAMNGYSMSQPMMNSGYHSNHGYMNQTPQYPMQMQMGMMGTQPYAQQPMQT
1690 1700 1710 1720 1730 1740
2050 2060 2070
pF1KE2 PPHGNMMYTAPGHHGYMNTGMSKQSLNGSYMRR
:::::::::::::::::::::::::::::::::
NP_001 PPHGNMMYTAPGHHGYMNTGMSKQSLNGSYMRR
1750 1760 1770 1780
2073 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Tue Nov 8 17:31:12 2016 done: Tue Nov 8 17:31:14 2016
Total Scan time: 14.650 Total Display time: 1.140
Function used was FASTA [36.3.4 Apr, 2011]