Result of FASTA (ccds) for
pFN21AE2697
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE2697, 632 aa
1>>>pF1KE2697 632 - 632 aa - 632 aa
Library: human.CCDS.faa
18511270 residues in 32554 sequences
Statistics: Expectation_n fit: rho(ln(x))= 6.8737+/-0.000972; mu= 13.7879+/- 0.059
mean_var=147.1962+/-29.611, 0's: 0 Z-trim(109.8): 30 B-trim: 18 in 1/51
Lambda= 0.105712
statistics sampled from 11116 (11131) to 11116 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.682), E-opt: 0.2 (0.342), width: 16
Scan time: 2.010
The best scores are: opt bits E(32554)
CCDS14682.1 FMR1 gene_id:2332|Hs108|chrX ( 632) 4220 655.7 5.3e-188
CCDS55518.1 FMR1 gene_id:2332|Hs108|chrX ( 537) 2801 439.2 6.6e-123
CCDS76039.1 FMR1 gene_id:2332|Hs108|chrX ( 586) 2507 394.4 2.2e-109
CCDS55519.1 FMR1 gene_id:2332|Hs108|chrX ( 611) 2487 391.4 1.9e-108
CCDS46965.1 FXR1 gene_id:8087|Hs108|chr3 ( 539) 1670 266.8 5.5e-71
CCDS3238.1 FXR1 gene_id:8087|Hs108|chr3 ( 621) 1670 266.8 6.1e-71
CCDS45604.1 FXR2 gene_id:9513|Hs108|chr17 ( 673) 1604 256.8 7e-68
CCDS33894.1 FXR1 gene_id:8087|Hs108|chr3 ( 536) 1194 194.2 3.9e-49
>>CCDS14682.1 FMR1 gene_id:2332|Hs108|chrX (632 aa)
initn: 4220 init1: 4220 opt: 4220 Z-score: 3488.7 bits: 655.7 E(32554): 5.3e-188
Smith-Waterman score: 4220; 100.0% identity (100.0% similar) in 632 aa overlap (1-632:1-632)
10 20 30 40 50 60
pF1KE2 MEELVVEVRGSNGAFYKAFVKDVHEDSITVAFENNWQPDRQIPFHDVRFPPPVGYNKDIN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS14 MEELVVEVRGSNGAFYKAFVKDVHEDSITVAFENNWQPDRQIPFHDVRFPPPVGYNKDIN
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE2 ESDEVEVYSRANEKEPCCWWLAKVRMIKGEFYVIEYAACDATYNEIVTIERLRSVNPNKP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS14 ESDEVEVYSRANEKEPCCWWLAKVRMIKGEFYVIEYAACDATYNEIVTIERLRSVNPNKP
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE2 ATKDTFHKIKLDVPEDLRQMCAKEAAHKDFKKAVGAFSVTYDPENYQLVILSINEVTSKR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS14 ATKDTFHKIKLDVPEDLRQMCAKEAAHKDFKKAVGAFSVTYDPENYQLVILSINEVTSKR
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE2 AHMLIDMHFRSLRTKLSLIMRNEEASKQLESSRQLASRFHEQFIVREDLMGLAIGTHGAN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS14 AHMLIDMHFRSLRTKLSLIMRNEEASKQLESSRQLASRFHEQFIVREDLMGLAIGTHGAN
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE2 IQQARKVPGVTAIDLDEDTCTFHIYGEDQDAVKKARSFLEFAEDVIQVPRNLVGKVIGKN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS14 IQQARKVPGVTAIDLDEDTCTFHIYGEDQDAVKKARSFLEFAEDVIQVPRNLVGKVIGKN
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE2 GKLIQEIVDKSGVVRVRIEAENEKNVPQEEEIMPPNSLPSNNSRVGPNAPEEKKHLDIKE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS14 GKLIQEIVDKSGVVRVRIEAENEKNVPQEEEIMPPNSLPSNNSRVGPNAPEEKKHLDIKE
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE2 NSTHFSQPNSTKVQRVLVASSVVAGESQKPELKAWQGMVPFVFVGTKDSIANATVLLDYH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS14 NSTHFSQPNSTKVQRVLVASSVVAGESQKPELKAWQGMVPFVFVGTKDSIANATVLLDYH
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE2 LNYLKEVDQLRLERLQIDEQLRQIGASSRPPPNRTDKEKSYVTDDGQGMGRGSRPYRNRG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS14 LNYLKEVDQLRLERLQIDEQLRQIGASSRPPPNRTDKEKSYVTDDGQGMGRGSRPYRNRG
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE2 HGRRGPGYTSGTNSEASNASETESDHRDELSDWSLAPTEEERESFLRRGDGRRRGGGGRG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS14 HGRRGPGYTSGTNSEASNASETESDHRDELSDWSLAPTEEERESFLRRGDGRRRGGGGRG
490 500 510 520 530 540
550 560 570 580 590 600
pF1KE2 QGGRGRGGGFKGNDDHSRTDNRPRNPREAKGRTTDGSLQIRVDCNNERSVHTKTLQNTSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS14 QGGRGRGGGFKGNDDHSRTDNRPRNPREAKGRTTDGSLQIRVDCNNERSVHTKTLQNTSS
550 560 570 580 590 600
610 620 630
pF1KE2 EGSRLRTGKDRNQKKEKPDSVDGQQPLVNGVP
::::::::::::::::::::::::::::::::
CCDS14 EGSRLRTGKDRNQKKEKPDSVDGQQPLVNGVP
610 620 630
>>CCDS55518.1 FMR1 gene_id:2332|Hs108|chrX (537 aa)
initn: 2826 init1: 2801 opt: 2801 Z-score: 2320.1 bits: 439.2 E(32554): 6.6e-123
Smith-Waterman score: 2801; 100.0% identity (100.0% similar) in 425 aa overlap (1-425:1-425)
10 20 30 40 50 60
pF1KE2 MEELVVEVRGSNGAFYKAFVKDVHEDSITVAFENNWQPDRQIPFHDVRFPPPVGYNKDIN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS55 MEELVVEVRGSNGAFYKAFVKDVHEDSITVAFENNWQPDRQIPFHDVRFPPPVGYNKDIN
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE2 ESDEVEVYSRANEKEPCCWWLAKVRMIKGEFYVIEYAACDATYNEIVTIERLRSVNPNKP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS55 ESDEVEVYSRANEKEPCCWWLAKVRMIKGEFYVIEYAACDATYNEIVTIERLRSVNPNKP
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE2 ATKDTFHKIKLDVPEDLRQMCAKEAAHKDFKKAVGAFSVTYDPENYQLVILSINEVTSKR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS55 ATKDTFHKIKLDVPEDLRQMCAKEAAHKDFKKAVGAFSVTYDPENYQLVILSINEVTSKR
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE2 AHMLIDMHFRSLRTKLSLIMRNEEASKQLESSRQLASRFHEQFIVREDLMGLAIGTHGAN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS55 AHMLIDMHFRSLRTKLSLIMRNEEASKQLESSRQLASRFHEQFIVREDLMGLAIGTHGAN
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE2 IQQARKVPGVTAIDLDEDTCTFHIYGEDQDAVKKARSFLEFAEDVIQVPRNLVGKVIGKN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS55 IQQARKVPGVTAIDLDEDTCTFHIYGEDQDAVKKARSFLEFAEDVIQVPRNLVGKVIGKN
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE2 GKLIQEIVDKSGVVRVRIEAENEKNVPQEEEIMPPNSLPSNNSRVGPNAPEEKKHLDIKE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS55 GKLIQEIVDKSGVVRVRIEAENEKNVPQEEEIMPPNSLPSNNSRVGPNAPEEKKHLDIKE
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE2 NSTHFSQPNSTKVQRVLVASSVVAGESQKPELKAWQGMVPFVFVGTKDSIANATVLLDYH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS55 NSTHFSQPNSTKVQRVLVASSVVAGESQKPELKAWQGMVPFVFVGTKDSIANATVLLDYH
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE2 LNYLKEVDQLRLERLQIDEQLRQIGASSRPPPNRTDKEKSYVTDDGQGMGRGSRPYRNRG
:::::
CCDS55 LNYLKLQQRKRGRASCAEETDGGVEGEEEDKEEEDVEEASKETTITPEQIIVHVIQERLK
430 440 450 460 470 480
>>CCDS76039.1 FMR1 gene_id:2332|Hs108|chrX (586 aa)
initn: 3299 init1: 2487 opt: 2507 Z-score: 2077.3 bits: 394.4 E(32554): 2.2e-109
Smith-Waterman score: 3815; 92.7% identity (92.7% similar) in 632 aa overlap (1-632:1-586)
10 20 30 40 50 60
pF1KE2 MEELVVEVRGSNGAFYKAFVKDVHEDSITVAFENNWQPDRQIPFHDVRFPPPVGYNKDIN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS76 MEELVVEVRGSNGAFYKAFVKDVHEDSITVAFENNWQPDRQIPFHDVRFPPPVGYNKDIN
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE2 ESDEVEVYSRANEKEPCCWWLAKVRMIKGEFYVIEYAACDATYNEIVTIERLRSVNPNKP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS76 ESDEVEVYSRANEKEPCCWWLAKVRMIKGEFYVIEYAACDATYNEIVTIERLRSVNPNKP
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE2 ATKDTFHKIKLDVPEDLRQMCAKEAAHKDFKKAVGAFSVTYDPENYQLVILSINEVTSKR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS76 ATKDTFHKIKLDVPEDLRQMCAKEAAHKDFKKAVGAFSVTYDPENYQLVILSINEVTSKR
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE2 AHMLIDMHFRSLRTKLSLIMRNEEASKQLESSRQLASRFHEQFIVREDLMGLAIGTHGAN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS76 AHMLIDMHFRSLRTKLSLIMRNEEASKQLESSRQLASRFHEQFIVREDLMGLAIGTHGAN
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE2 IQQARKVPGVTAIDLDEDTCTFHIYGEDQDAVKKARSFLEFAEDVIQVPRNLVGKVIGKN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS76 IQQARKVPGVTAIDLDEDTCTFHIYGEDQDAVKKARSFLEFAEDVIQVPRNLVGKVIGKN
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE2 GKLIQEIVDKSGVVRVRIEAENEKNVPQEEEIMPPNSLPSNNSRVGPNAPEEKKHLDIKE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS76 GKLIQEIVDKSGVVRVRIEAENEKNVPQEEEIMPPNSLPSNNSRVGPNAPEEKKHLDIKE
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE2 NSTHFSQPNSTKVQRVLVASSVVAGESQKPELKAWQGMVPFVFVGTKDSIANATVLLDYH
::::::::::::::: ::::::::::::::::::::::::
CCDS76 NSTHFSQPNSTKVQR---------------------GMVPFVFVGTKDSIANATVLLDYH
370 380 390
430 440 450 460 470 480
pF1KE2 LNYLKEVDQLRLERLQIDEQLRQIGASSRPPPNRTDKEKSYVTDDGQGMGRGSRPYRNRG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS76 LNYLKEVDQLRLERLQIDEQLRQIGASSRPPPNRTDKEKSYVTDDGQGMGRGSRPYRNRG
400 410 420 430 440 450
490 500 510 520 530 540
pF1KE2 HGRRGPGYTSGTNSEASNASETESDHRDELSDWSLAPTEEERESFLRRGDGRRRGGGGRG
:::::::::: :::::::::::::::::::::::::
CCDS76 HGRRGPGYTS-------------------------APTEEERESFLRRGDGRRRGGGGRG
460 470 480 490
550 560 570 580 590 600
pF1KE2 QGGRGRGGGFKGNDDHSRTDNRPRNPREAKGRTTDGSLQIRVDCNNERSVHTKTLQNTSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS76 QGGRGRGGGFKGNDDHSRTDNRPRNPREAKGRTTDGSLQIRVDCNNERSVHTKTLQNTSS
500 510 520 530 540 550
610 620 630
pF1KE2 EGSRLRTGKDRNQKKEKPDSVDGQQPLVNGVP
::::::::::::::::::::::::::::::::
CCDS76 EGSRLRTGKDRNQKKEKPDSVDGQQPLVNGVP
560 570 580
>>CCDS55519.1 FMR1 gene_id:2332|Hs108|chrX (611 aa)
initn: 2605 init1: 2487 opt: 2487 Z-score: 2060.5 bits: 391.4 E(32554): 1.9e-108
Smith-Waterman score: 4037; 96.7% identity (96.7% similar) in 632 aa overlap (1-632:1-611)
10 20 30 40 50 60
pF1KE2 MEELVVEVRGSNGAFYKAFVKDVHEDSITVAFENNWQPDRQIPFHDVRFPPPVGYNKDIN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS55 MEELVVEVRGSNGAFYKAFVKDVHEDSITVAFENNWQPDRQIPFHDVRFPPPVGYNKDIN
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE2 ESDEVEVYSRANEKEPCCWWLAKVRMIKGEFYVIEYAACDATYNEIVTIERLRSVNPNKP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS55 ESDEVEVYSRANEKEPCCWWLAKVRMIKGEFYVIEYAACDATYNEIVTIERLRSVNPNKP
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE2 ATKDTFHKIKLDVPEDLRQMCAKEAAHKDFKKAVGAFSVTYDPENYQLVILSINEVTSKR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS55 ATKDTFHKIKLDVPEDLRQMCAKEAAHKDFKKAVGAFSVTYDPENYQLVILSINEVTSKR
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE2 AHMLIDMHFRSLRTKLSLIMRNEEASKQLESSRQLASRFHEQFIVREDLMGLAIGTHGAN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS55 AHMLIDMHFRSLRTKLSLIMRNEEASKQLESSRQLASRFHEQFIVREDLMGLAIGTHGAN
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE2 IQQARKVPGVTAIDLDEDTCTFHIYGEDQDAVKKARSFLEFAEDVIQVPRNLVGKVIGKN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS55 IQQARKVPGVTAIDLDEDTCTFHIYGEDQDAVKKARSFLEFAEDVIQVPRNLVGKVIGKN
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE2 GKLIQEIVDKSGVVRVRIEAENEKNVPQEEEIMPPNSLPSNNSRVGPNAPEEKKHLDIKE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS55 GKLIQEIVDKSGVVRVRIEAENEKNVPQEEEIMPPNSLPSNNSRVGPNAPEEKKHLDIKE
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE2 NSTHFSQPNSTKVQRVLVASSVVAGESQKPELKAWQGMVPFVFVGTKDSIANATVLLDYH
::::::::::::::: ::::::::::::::::::::::::
CCDS55 NSTHFSQPNSTKVQR---------------------GMVPFVFVGTKDSIANATVLLDYH
370 380 390
430 440 450 460 470 480
pF1KE2 LNYLKEVDQLRLERLQIDEQLRQIGASSRPPPNRTDKEKSYVTDDGQGMGRGSRPYRNRG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS55 LNYLKEVDQLRLERLQIDEQLRQIGASSRPPPNRTDKEKSYVTDDGQGMGRGSRPYRNRG
400 410 420 430 440 450
490 500 510 520 530 540
pF1KE2 HGRRGPGYTSGTNSEASNASETESDHRDELSDWSLAPTEEERESFLRRGDGRRRGGGGRG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS55 HGRRGPGYTSGTNSEASNASETESDHRDELSDWSLAPTEEERESFLRRGDGRRRGGGGRG
460 470 480 490 500 510
550 560 570 580 590 600
pF1KE2 QGGRGRGGGFKGNDDHSRTDNRPRNPREAKGRTTDGSLQIRVDCNNERSVHTKTLQNTSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS55 QGGRGRGGGFKGNDDHSRTDNRPRNPREAKGRTTDGSLQIRVDCNNERSVHTKTLQNTSS
520 530 540 550 560 570
610 620 630
pF1KE2 EGSRLRTGKDRNQKKEKPDSVDGQQPLVNGVP
::::::::::::::::::::::::::::::::
CCDS55 EGSRLRTGKDRNQKKEKPDSVDGQQPLVNGVP
580 590 600 610
>>CCDS46965.1 FXR1 gene_id:8087|Hs108|chr3 (539 aa)
initn: 2142 init1: 1670 opt: 1670 Z-score: 1387.8 bits: 266.8 E(32554): 5.5e-71
Smith-Waterman score: 2036; 57.2% identity (71.7% similar) in 614 aa overlap (1-610:1-514)
10 20 30 40 50 60
pF1KE2 MEELVVEVRGSNGAFYKAFVKDVHEDSITVAFENNWQPDRQIPFHDVRFPPPVGYNKDIN
: ::.::::::::::::.:.:::::::.::.:::::::.::.::..::.::: .:.:.
CCDS46 MAELTVEVRGSNGAFYKGFIKDVHEDSLTVVFENNWQPERQVPFNEVRLPPPPDIKKEIS
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE2 ESDEVEVYSRANEKEPCCWWLAKVRMIKGEFYVIEYAACDATYNEIVTIERLRSVNPNKP
:.::::::::::..::: ::::::::.:::::::::::::::::::::.:::: :: ::
CCDS46 EGDEVEVYSRANDQEPCGWWLAKVRMMKGEFYVIEYAACDATYNEIVTFERLRPVNQNKT
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE2 ATKDTFHKIKLDVPEDLRQMCAKEAAHKDFKKAVGAFSVTYDPENYQLVILSINEVTSKR
. :.:: : .:::::::. ::.: ::::::::::: . : ::. ::.::: .:.: ::
CCDS46 VKKNTFFKCTVDVPEDLREACANENAHKDFKKAVGACRIFYHPETTQLMILSASEATVKR
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE2 AHMLIDMHFRSLRTKLSLIMRNEEASKQLESSRQLASRFHEQFIVREDLMGLAIGTHGAN
...: :::.::.:::: :. :::::.:.:: ..:::. :::.:.::::::::::::::.:
CCDS46 VNILSDMHLRSIRTKLMLMSRNEEATKHLECTKQLAAAFHEEFVVREDLMGLAIGTHGSN
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE2 IQQARKVPGVTAIDLDEDTCTFHIYGEDQDAVKKARSFLEFAEDVIQVPRNLVGKVIGKN
:::::::::::::.::::: ::.::::. :::::::.::::.:: :::::::::::::::
CCDS46 IQQARKVPGVTAIELDEDTGTFRIYGESADAVKKARGFLEFVEDFIQVPRNLVGKVIGKN
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE2 GKLIQEIVDKSGVVRVRIEAENEKNVPQEEEIMPPNSLPSNNSRVGPNAPEEKKHLDIKE
::.::::::::::::::::..::...:.:.
CCDS46 GKVIQEIVDKSGVVRVRIEGDNENKLPRED------------------------------
310 320 330
370 380 390 400 410 420
pF1KE2 NSTHFSQPNSTKVQRVLVASSVVAGESQKPELKAWQGMVPFVFVGTKDSIANATVLLDYH
:::::::::::.::.:. :::.::
CCDS46 ------------------------------------GMVPFVFVGTKESIGNVQVLLEYH
340 350
430 440 450 460 470 480
pF1KE2 LNYLKEVDQLRLERLQIDEQLRQIGASSRPPPNRTDKEKSYVTDDGQGMGRGSRPYRNRG
. :::::.:::.::::::::::::: :: : .::
CCDS46 IAYLKEVEQLRMERLQIDEQLRQIG---------------------------SRSYSGRG
360 370 380
490 500 510 520 530
pF1KE2 HGRRGPGYTSG--TNSEASNASETESDHRDELSDWSLAPTEEERESFLRRGDGRRRGGGG
.:::::.:::: :::: :: :::::...::::::::: :..:.: .: . :: :: :
CCDS46 RGRRGPNYTSGYGTNSELSNPSETESERKDELSDWSLAG-EDDRDSRHQRDSRRRPGGRG
390 400 410 420 430 440
540 550 560 570 580 590
pF1KE2 RG-QGGRGRGGGFKGNDDHSRTDNRP-RNPREAKGRTTDGSLQIRVDCNNERSVHTKTLQ
:. .::::::: :... : . . : :: : . . .: . .: :.
CCDS46 RSVSGGRGRGGPRGGKSSISSVLKDPDSNPYSLLDNTESDQT---ADTDASESHHS---T
450 460 470 480 490 500
600 610 620 630
pF1KE2 NTSSEGSRLRTGKDRNQKKEKPDSVDGQQPLVNGVP
: .. : :: .:
CCDS46 NRRRRSRRRRTDEDAVLMDGMTESDTASVNENGLGKRCD
510 520 530
>>CCDS3238.1 FXR1 gene_id:8087|Hs108|chr3 (621 aa)
initn: 2142 init1: 1670 opt: 1670 Z-score: 1387.0 bits: 266.8 E(32554): 6.1e-71
Smith-Waterman score: 2036; 57.2% identity (71.7% similar) in 614 aa overlap (1-610:1-514)
10 20 30 40 50 60
pF1KE2 MEELVVEVRGSNGAFYKAFVKDVHEDSITVAFENNWQPDRQIPFHDVRFPPPVGYNKDIN
: ::.::::::::::::.:.:::::::.::.:::::::.::.::..::.::: .:.:.
CCDS32 MAELTVEVRGSNGAFYKGFIKDVHEDSLTVVFENNWQPERQVPFNEVRLPPPPDIKKEIS
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE2 ESDEVEVYSRANEKEPCCWWLAKVRMIKGEFYVIEYAACDATYNEIVTIERLRSVNPNKP
:.::::::::::..::: ::::::::.:::::::::::::::::::::.:::: :: ::
CCDS32 EGDEVEVYSRANDQEPCGWWLAKVRMMKGEFYVIEYAACDATYNEIVTFERLRPVNQNKT
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE2 ATKDTFHKIKLDVPEDLRQMCAKEAAHKDFKKAVGAFSVTYDPENYQLVILSINEVTSKR
. :.:: : .:::::::. ::.: ::::::::::: . : ::. ::.::: .:.: ::
CCDS32 VKKNTFFKCTVDVPEDLREACANENAHKDFKKAVGACRIFYHPETTQLMILSASEATVKR
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE2 AHMLIDMHFRSLRTKLSLIMRNEEASKQLESSRQLASRFHEQFIVREDLMGLAIGTHGAN
...: :::.::.:::: :. :::::.:.:: ..:::. :::.:.::::::::::::::.:
CCDS32 VNILSDMHLRSIRTKLMLMSRNEEATKHLECTKQLAAAFHEEFVVREDLMGLAIGTHGSN
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE2 IQQARKVPGVTAIDLDEDTCTFHIYGEDQDAVKKARSFLEFAEDVIQVPRNLVGKVIGKN
:::::::::::::.::::: ::.::::. :::::::.::::.:: :::::::::::::::
CCDS32 IQQARKVPGVTAIELDEDTGTFRIYGESADAVKKARGFLEFVEDFIQVPRNLVGKVIGKN
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE2 GKLIQEIVDKSGVVRVRIEAENEKNVPQEEEIMPPNSLPSNNSRVGPNAPEEKKHLDIKE
::.::::::::::::::::..::...:.:.
CCDS32 GKVIQEIVDKSGVVRVRIEGDNENKLPRED------------------------------
310 320 330
370 380 390 400 410 420
pF1KE2 NSTHFSQPNSTKVQRVLVASSVVAGESQKPELKAWQGMVPFVFVGTKDSIANATVLLDYH
:::::::::::.::.:. :::.::
CCDS32 ------------------------------------GMVPFVFVGTKESIGNVQVLLEYH
340 350
430 440 450 460 470 480
pF1KE2 LNYLKEVDQLRLERLQIDEQLRQIGASSRPPPNRTDKEKSYVTDDGQGMGRGSRPYRNRG
. :::::.:::.::::::::::::: :: : .::
CCDS32 IAYLKEVEQLRMERLQIDEQLRQIG---------------------------SRSYSGRG
360 370 380
490 500 510 520 530
pF1KE2 HGRRGPGYTSG--TNSEASNASETESDHRDELSDWSLAPTEEERESFLRRGDGRRRGGGG
.:::::.:::: :::: :: :::::...::::::::: :..:.: .: . :: :: :
CCDS32 RGRRGPNYTSGYGTNSELSNPSETESERKDELSDWSLAG-EDDRDSRHQRDSRRRPGGRG
390 400 410 420 430 440
540 550 560 570 580 590
pF1KE2 RG-QGGRGRGGGFKGNDDHSRTDNRP-RNPREAKGRTTDGSLQIRVDCNNERSVHTKTLQ
:. .::::::: :... : . . : :: : . . .: . .: :.
CCDS32 RSVSGGRGRGGPRGGKSSISSVLKDPDSNPYSLLDNTESDQT---ADTDASESHHS---T
450 460 470 480 490 500
600 610 620 630
pF1KE2 NTSSEGSRLRTGKDRNQKKEKPDSVDGQQPLVNGVP
: .. : :: .:
CCDS32 NRRRRSRRRRTDEDAVLMDGMTESDTASVNENGLVTVADYISRAESQSRQRNLPRETLAK
510 520 530 540 550 560
>>CCDS45604.1 FXR2 gene_id:9513|Hs108|chr17 (673 aa)
initn: 1789 init1: 1604 opt: 1604 Z-score: 1332.2 bits: 256.8 E(32554): 7e-68
Smith-Waterman score: 1861; 56.8% identity (73.6% similar) in 549 aa overlap (4-542:14-491)
10 20 30 40 50
pF1KE2 MEELVVEVRGSNGAFYKAFVKDVHEDSITVAFENNWQPDRQIPFHDVRFP
: ::::::::::::.:::::::::.:. :::::: .::::: :::.:
CCDS45 MGGLASGGDVEPGLPVEVRGSNGAFYKGFVKDVHEDSVTIFFENNWQSERQIPFGDVRLP
10 20 30 40 50 60
60 70 80 90 100 110
pF1KE2 PPVGYNKDINESDEVEVYSRANEKEPCCWWLAKVRMIKGEFYVIEYAACDATYNEIVTIE
::. :::.:.:.:::::::::::.::: ::::.:::.::.::::::::::::::::::.:
CCDS45 PPADYNKEITEGDEVEVYSRANEQEPCGWWLARVRMMKGDFYVIEYAACDATYNEIVTLE
70 80 90 100 110 120
120 130 140 150 160 170
pF1KE2 RLRSVNPNKPATKDTFHKIKLDVPEDLRQMCAKEAAHKDFKKAVGAFSVTYDPENYQLVI
::: :::: ::: .: :. . ::::::. :..: .::.::::.:: . . : .: :
CCDS45 RLRPVNPNPLATKGSFFKVTMAVPEDLREACSNENVHKEFKKALGANCIFLNITNSELFI
130 140 150 160 170 180
180 190 200 210 220 230
pF1KE2 LSINEVTSKRAHMLIDMHFRSLRTKLSLIMRNEEASKQLESSRQLASRFHEQFIVREDLM
:: .:. ::: .: ::::::::::: :. :::::.:.::.:.:::. :.:.: ::::::
CCDS45 LSTTEAPVKRASLLGDMHFRSLRTKLLLMSRNEEATKHLETSKQLAAAFQEEFTVREDLM
190 200 210 220 230 240
240 250 260 270 280 290
pF1KE2 GLAIGTHGANIQQARKVPGVTAIDLDEDTCTFHIYGEDQDAVKKARSFLEFAEDVIQVPR
:::::::::::::::::::::::.: :.::::.:::: .: ..:::.:::.:: .::::
CCDS45 GLAIGTHGANIQQARKVPGVTAIELGEETCTFRIYGETPEACRQARSYLEFSEDSVQVPR
250 260 270 280 290 300
300 310 320 330 340 350
pF1KE2 NLVGKVIGKNGKLIQEIVDKSGVVRVRIEAENEKNVPQEEEIMPPNSLPSNNSRVGPNAP
::::::::::::.::::::::::::::.:..:.:. :.::
CCDS45 NLVGKVIGKNGKVIQEIVDKSGVVRVRVEGDNDKKNPREE--------------------
310 320 330 340
360 370 380 390 400 410
pF1KE2 EEKKHLDIKENSTHFSQPNSTKVQRVLVASSVVAGESQKPELKAWQGMVPFVFVGTKDSI
:::::.::::...:
CCDS45 ----------------------------------------------GMVPFIFVGTRENI
350
420 430 440 450 460
pF1KE2 ANATVLLDYHLNYLKEVDQLRLERLQIDEQLRQIGASSRPPPNR-----TDKEKSYVTDD
.:: .::.:::.::.::.::::::::::::::::: . ::: . .:: .: ::.
CCDS45 SNAQALLEYHLSYLQEVEQLRLERLQIDEQLRQIGLGFRPPGSGRGSGGSDKA-GYSTDE
360 370 380 390 400 410
470 480 490 500 510 520
pF1KE2 GQGMG-RGSRPYRN----RGHGRRGPGYTSGTNSEASNASETESDHRDELSDWSLAPTEE
... . ...: : . ::.::: : . : .:..:.::::::..:.: . .:
CCDS45 SSSSSLHATRTYGGSYGGRGRGRRTGGPAYGPSSDVSTASETESEKREEPN--RAGPG--
420 430 440 450 460
530 540 550 560 570 580
pF1KE2 ERESFLRRGDGRRRGGGGRGQGGRGRGGGFKGNDDHSRTDNRPRNPREAKGRTTDGSLQI
.:. : ..::: ::::.:
CCDS45 DRDPPTRGEESRRRPTGGRGRGPPPAPRPTSRYNSSSISSVLKDPDSNPYSLLDTSEPEP
470 480 490 500 510 520
>>CCDS33894.1 FXR1 gene_id:8087|Hs108|chr3 (536 aa)
initn: 1666 init1: 1194 opt: 1194 Z-score: 995.5 bits: 194.2 E(32554): 3.9e-49
Smith-Waterman score: 1560; 54.3% identity (68.1% similar) in 529 aa overlap (86-610:1-429)
60 70 80 90 100 110
pF1KE2 NKDINESDEVEVYSRANEKEPCCWWLAKVRMIKGEFYVIEYAACDATYNEIVTIERLRSV
:.:::::::::::::::::::::.:::: :
CCDS33 MMKGEFYVIEYAACDATYNEIVTFERLRPV
10 20 30
120 130 140 150 160 170
pF1KE2 NPNKPATKDTFHKIKLDVPEDLRQMCAKEAAHKDFKKAVGAFSVTYDPENYQLVILSINE
: :: . :.:: : .:::::::. ::.: ::::::::::: . : ::. ::.::: .:
CCDS33 NQNKTVKKNTFFKCTVDVPEDLREACANENAHKDFKKAVGACRIFYHPETTQLMILSASE
40 50 60 70 80 90
180 190 200 210 220 230
pF1KE2 VTSKRAHMLIDMHFRSLRTKLSLIMRNEEASKQLESSRQLASRFHEQFIVREDLMGLAIG
.: ::...: :::.::.:::: :. :::::.:.:: ..:::. :::.:.:::::::::::
CCDS33 ATVKRVNILSDMHLRSIRTKLMLMSRNEEATKHLECTKQLAAAFHEEFVVREDLMGLAIG
100 110 120 130 140 150
240 250 260 270 280 290
pF1KE2 THGANIQQARKVPGVTAIDLDEDTCTFHIYGEDQDAVKKARSFLEFAEDVIQVPRNLVGK
:::.::::::::::::::.::::: ::.::::. :::::::.::::.:: ::::::::::
CCDS33 THGSNIQQARKVPGVTAIELDEDTGTFRIYGESADAVKKARGFLEFVEDFIQVPRNLVGK
160 170 180 190 200 210
300 310 320 330 340 350
pF1KE2 VIGKNGKLIQEIVDKSGVVRVRIEAENEKNVPQEEEIMPPNSLPSNNSRVGPNAPEEKKH
:::::::.::::::::::::::::..::...:.:.
CCDS33 VIGKNGKVIQEIVDKSGVVRVRIEGDNENKLPRED-------------------------
220 230 240
360 370 380 390 400 410
pF1KE2 LDIKENSTHFSQPNSTKVQRVLVASSVVAGESQKPELKAWQGMVPFVFVGTKDSIANATV
:::::::::::.::.:. :
CCDS33 -----------------------------------------GMVPFVFVGTKESIGNVQV
250 260
420 430 440 450 460 470
pF1KE2 LLDYHLNYLKEVDQLRLERLQIDEQLRQIGASSRPPPNRTDKEKSYVTDDGQGMGRGSRP
::.::. :::::.:::.::::::::::::: ::
CCDS33 LLEYHIAYLKEVEQLRMERLQIDEQLRQIG---------------------------SRS
270 280 290
480 490 500 510 520 530
pF1KE2 YRNRGHGRRGPGYTSG--TNSEASNASETESDHRDELSDWSLAPTEEERESFLRRGDGRR
: .::.:::::.:::: :::: :: :::::...::::::::: :..:.: .: . ::
CCDS33 YSGRGRGRRGPNYTSGYGTNSELSNPSETESERKDELSDWSLAG-EDDRDSRHQRDSRRR
300 310 320 330 340 350
540 550 560 570 580 590
pF1KE2 RGGGGRG-QGGRGRGGGFKGNDDHSRTDNRP-RNPREAKGRTTDGSLQIRVDCNNERSVH
:: ::. .::::::: :... : . . : :: : . . .: . .: :
CCDS33 PGGRGRSVSGGRGRGGPRGGKSSISSVLKDPDSNPYSLLDNTESDQT---ADTDASESHH
360 370 380 390 400 410
600 610 620 630
pF1KE2 TKTLQNTSSEGSRLRTGKDRNQKKEKPDSVDGQQPLVNGVP
. : .. : :: .:
CCDS33 ST---NRRRRSRRRRTDEDAVLMDGMTESDTASVNENGLVTVADYISRAESQSRQRNLPR
420 430 440 450 460 470
632 residues in 1 query sequences
18511270 residues in 32554 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Fri Jun 16 16:56:31 2017 done: Fri Jun 16 16:56:32 2017
Total Scan time: 2.010 Total Display time: 0.060
Function used was FASTA [36.3.4 Apr, 2011]