Result of FASTA (omim) for
pFN21AE2702
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE2702, 429 aa
1>>>pF1KE2702 429 - 429 aa - 429 aa
Library: /omim/omim.rfq.tfa
63214209 residues in 88908 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.3735+/-0.000371; mu= 16.8732+/- 0.023
mean_var=69.0738+/-13.719, 0's: 0 Z-trim(113.1): 9 B-trim: 0 in 0/56
Lambda= 0.154318
statistics sampled from 22801 (22807) to 22801 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.63), E-opt: 0.2 (0.257), width: 16
Scan time: 7.400
The best scores are: opt bits E(88908)
NP_001012533 (OMIM: 177000,612386) ferrochelatase, ( 429) 2909 656.9 2.9e-188
NP_000131 (OMIM: 177000,612386) ferrochelatase, mi ( 423) 2849 643.6 3e-184
XP_011524184 (OMIM: 177000,612386) PREDICTED: ferr ( 351) 2389 541.1 1.7e-153
XP_011524183 (OMIM: 177000,612386) PREDICTED: ferr ( 396) 1641 374.6 2.6e-103
XP_016881103 (OMIM: 177000,612386) PREDICTED: ferr ( 390) 1581 361.2 2.7e-99
>>NP_001012533 (OMIM: 177000,612386) ferrochelatase, mit (429 aa)
initn: 2909 init1: 2909 opt: 2909 Z-score: 3501.3 bits: 656.9 E(88908): 2.9e-188
Smith-Waterman score: 2909; 100.0% identity (100.0% similar) in 429 aa overlap (1-429:1-429)
10 20 30 40 50 60
pF1KE2 MRSLGANMAAALRAAGVLLRDPLASSSWRVCQPWRWKSGAAAAAVTTETAQHAQGAKPQV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MRSLGANMAAALRAAGVLLRDPLASSSWRVCQPWRWKSGAAAAAVTTETAQHAQGAKPQV
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE2 QPQKRYESNIRKPKTGILMLNMGGPETLGDVHDFLLRLFLDRDLMTLPIQNKLAPFIAKR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QPQKRYESNIRKPKTGILMLNMGGPETLGDVHDFLLRLFLDRDLMTLPIQNKLAPFIAKR
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE2 RTPKIQEQYRRIGGGSPIKIWTSKQGEGMVKLLDELSPNTAPHKYYIGFRYVHPLTEEAI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RTPKIQEQYRRIGGGSPIKIWTSKQGEGMVKLLDELSPNTAPHKYYIGFRYVHPLTEEAI
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE2 EEMERDGLERAIAFTQYPQYSCSTTGSSLNAIYRYYNQVGRKPTMKWSTIDRWPTHHLLI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EEMERDGLERAIAFTQYPQYSCSTTGSSLNAIYRYYNQVGRKPTMKWSTIDRWPTHHLLI
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE2 QCFADHILKELDHFPLEKRSEVVILFSAHSLPMSVVNRGDPYPQEVSATVQKVMERLEYC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QCFADHILKELDHFPLEKRSEVVILFSAHSLPMSVVNRGDPYPQEVSATVQKVMERLEYC
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE2 NPYRLVWQSKVGPMPWLGPQTDESIKGLCERGRKNILLVPIAFTSDHIETLYELDIEYSQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NPYRLVWQSKVGPMPWLGPQTDESIKGLCERGRKNILLVPIAFTSDHIETLYELDIEYSQ
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE2 VLAKECGVENIRRAESLNGNPLFSKALADLVHSHIQSNELCSKQLTLSCPLCVNPVCRET
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VLAKECGVENIRRAESLNGNPLFSKALADLVHSHIQSNELCSKQLTLSCPLCVNPVCRET
370 380 390 400 410 420
pF1KE2 KSFFTSQQL
:::::::::
NP_001 KSFFTSQQL
>>NP_000131 (OMIM: 177000,612386) ferrochelatase, mitoch (423 aa)
initn: 2441 init1: 2441 opt: 2849 Z-score: 3429.2 bits: 643.6 E(88908): 3e-184
Smith-Waterman score: 2849; 98.6% identity (98.6% similar) in 429 aa overlap (1-429:1-423)
10 20 30 40 50 60
pF1KE2 MRSLGANMAAALRAAGVLLRDPLASSSWRVCQPWRWKSGAAAAAVTTETAQHAQGAKPQV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 MRSLGANMAAALRAAGVLLRDPLASSSWRVCQPWRWKSGAAAAAVTTETAQHAQGAKPQV
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE2 QPQKRYESNIRKPKTGILMLNMGGPETLGDVHDFLLRLFLDRDLMTLPIQNKLAPFIAKR
::::: :::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 QPQKR------KPKTGILMLNMGGPETLGDVHDFLLRLFLDRDLMTLPIQNKLAPFIAKR
70 80 90 100 110
130 140 150 160 170 180
pF1KE2 RTPKIQEQYRRIGGGSPIKIWTSKQGEGMVKLLDELSPNTAPHKYYIGFRYVHPLTEEAI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 RTPKIQEQYRRIGGGSPIKIWTSKQGEGMVKLLDELSPNTAPHKYYIGFRYVHPLTEEAI
120 130 140 150 160 170
190 200 210 220 230 240
pF1KE2 EEMERDGLERAIAFTQYPQYSCSTTGSSLNAIYRYYNQVGRKPTMKWSTIDRWPTHHLLI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 EEMERDGLERAIAFTQYPQYSCSTTGSSLNAIYRYYNQVGRKPTMKWSTIDRWPTHHLLI
180 190 200 210 220 230
250 260 270 280 290 300
pF1KE2 QCFADHILKELDHFPLEKRSEVVILFSAHSLPMSVVNRGDPYPQEVSATVQKVMERLEYC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 QCFADHILKELDHFPLEKRSEVVILFSAHSLPMSVVNRGDPYPQEVSATVQKVMERLEYC
240 250 260 270 280 290
310 320 330 340 350 360
pF1KE2 NPYRLVWQSKVGPMPWLGPQTDESIKGLCERGRKNILLVPIAFTSDHIETLYELDIEYSQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 NPYRLVWQSKVGPMPWLGPQTDESIKGLCERGRKNILLVPIAFTSDHIETLYELDIEYSQ
300 310 320 330 340 350
370 380 390 400 410 420
pF1KE2 VLAKECGVENIRRAESLNGNPLFSKALADLVHSHIQSNELCSKQLTLSCPLCVNPVCRET
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 VLAKECGVENIRRAESLNGNPLFSKALADLVHSHIQSNELCSKQLTLSCPLCVNPVCRET
360 370 380 390 400 410
pF1KE2 KSFFTSQQL
:::::::::
NP_000 KSFFTSQQL
420
>>XP_011524184 (OMIM: 177000,612386) PREDICTED: ferroche (351 aa)
initn: 2389 init1: 2389 opt: 2389 Z-score: 2876.9 bits: 541.1 E(88908): 1.7e-153
Smith-Waterman score: 2389; 100.0% identity (100.0% similar) in 351 aa overlap (79-429:1-351)
50 60 70 80 90 100
pF1KE2 TAQHAQGAKPQVQPQKRYESNIRKPKTGILMLNMGGPETLGDVHDFLLRLFLDRDLMTLP
::::::::::::::::::::::::::::::
XP_011 MLNMGGPETLGDVHDFLLRLFLDRDLMTLP
10 20 30
110 120 130 140 150 160
pF1KE2 IQNKLAPFIAKRRTPKIQEQYRRIGGGSPIKIWTSKQGEGMVKLLDELSPNTAPHKYYIG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 IQNKLAPFIAKRRTPKIQEQYRRIGGGSPIKIWTSKQGEGMVKLLDELSPNTAPHKYYIG
40 50 60 70 80 90
170 180 190 200 210 220
pF1KE2 FRYVHPLTEEAIEEMERDGLERAIAFTQYPQYSCSTTGSSLNAIYRYYNQVGRKPTMKWS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FRYVHPLTEEAIEEMERDGLERAIAFTQYPQYSCSTTGSSLNAIYRYYNQVGRKPTMKWS
100 110 120 130 140 150
230 240 250 260 270 280
pF1KE2 TIDRWPTHHLLIQCFADHILKELDHFPLEKRSEVVILFSAHSLPMSVVNRGDPYPQEVSA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TIDRWPTHHLLIQCFADHILKELDHFPLEKRSEVVILFSAHSLPMSVVNRGDPYPQEVSA
160 170 180 190 200 210
290 300 310 320 330 340
pF1KE2 TVQKVMERLEYCNPYRLVWQSKVGPMPWLGPQTDESIKGLCERGRKNILLVPIAFTSDHI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TVQKVMERLEYCNPYRLVWQSKVGPMPWLGPQTDESIKGLCERGRKNILLVPIAFTSDHI
220 230 240 250 260 270
350 360 370 380 390 400
pF1KE2 ETLYELDIEYSQVLAKECGVENIRRAESLNGNPLFSKALADLVHSHIQSNELCSKQLTLS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ETLYELDIEYSQVLAKECGVENIRRAESLNGNPLFSKALADLVHSHIQSNELCSKQLTLS
280 290 300 310 320 330
410 420
pF1KE2 CPLCVNPVCRETKSFFTSQQL
:::::::::::::::::::::
XP_011 CPLCVNPVCRETKSFFTSQQL
340 350
>>XP_011524183 (OMIM: 177000,612386) PREDICTED: ferroche (396 aa)
initn: 1633 init1: 1633 opt: 1641 Z-score: 1976.1 bits: 374.6 E(88908): 2.6e-103
Smith-Waterman score: 2611; 92.3% identity (92.3% similar) in 429 aa overlap (1-429:1-396)
10 20 30 40 50 60
pF1KE2 MRSLGANMAAALRAAGVLLRDPLASSSWRVCQPWRWKSGAAAAAVTTETAQHAQGAKPQV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MRSLGANMAAALRAAGVLLRDPLASSSWRVCQPWRWKSGAAAAAVTTETAQHAQGAKPQV
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE2 QPQKRYESNIRKPKTGILMLNMGGPETLGDVHDFLLRLFLDRDLMTLPIQNKLAPFIAKR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QPQKRYESNIRKPKTGILMLNMGGPETLGDVHDFLLRLFLDRDLMTLPIQNKLAPFIAKR
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE2 RTPKIQEQYRRIGGGSPIKIWTSKQGEGMVKLLDELSPNTAPHKYYIGFRYVHPLTEEAI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RTPKIQEQYRRIGGGSPIKIWTSKQGEGMVKLLDELSPNTAPHKYYIGFRYVHPLTEEAI
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE2 EEMERDGLERAIAFTQYPQYSCSTTGSSLNAIYRYYNQVGRKPTMKWSTIDRWPTHHLLI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EEMERDGLERAIAFTQYPQYSCSTTGSSLNAIYRYYNQVGRKPTMKWSTIDRWPTHHLLI
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE2 QCFADHILKELDHFPLEKRSEVVILFSAHSLPMSVVNRGDPYPQEVSATVQKVMERLEYC
: ::::::::::::::::::::::::::
XP_011 Q---------------------------------VVNRGDPYPQEVSATVQKVMERLEYC
250 260
310 320 330 340 350 360
pF1KE2 NPYRLVWQSKVGPMPWLGPQTDESIKGLCERGRKNILLVPIAFTSDHIETLYELDIEYSQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NPYRLVWQSKVGPMPWLGPQTDESIKGLCERGRKNILLVPIAFTSDHIETLYELDIEYSQ
270 280 290 300 310 320
370 380 390 400 410 420
pF1KE2 VLAKECGVENIRRAESLNGNPLFSKALADLVHSHIQSNELCSKQLTLSCPLCVNPVCRET
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VLAKECGVENIRRAESLNGNPLFSKALADLVHSHIQSNELCSKQLTLSCPLCVNPVCRET
330 340 350 360 370 380
pF1KE2 KSFFTSQQL
:::::::::
XP_011 KSFFTSQQL
390
>>XP_016881103 (OMIM: 177000,612386) PREDICTED: ferroche (390 aa)
initn: 1489 init1: 1165 opt: 1581 Z-score: 1904.0 bits: 361.2 E(88908): 2.7e-99
Smith-Waterman score: 2551; 90.9% identity (90.9% similar) in 429 aa overlap (1-429:1-390)
10 20 30 40 50 60
pF1KE2 MRSLGANMAAALRAAGVLLRDPLASSSWRVCQPWRWKSGAAAAAVTTETAQHAQGAKPQV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MRSLGANMAAALRAAGVLLRDPLASSSWRVCQPWRWKSGAAAAAVTTETAQHAQGAKPQV
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE2 QPQKRYESNIRKPKTGILMLNMGGPETLGDVHDFLLRLFLDRDLMTLPIQNKLAPFIAKR
::::: :::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QPQKR------KPKTGILMLNMGGPETLGDVHDFLLRLFLDRDLMTLPIQNKLAPFIAKR
70 80 90 100 110
130 140 150 160 170 180
pF1KE2 RTPKIQEQYRRIGGGSPIKIWTSKQGEGMVKLLDELSPNTAPHKYYIGFRYVHPLTEEAI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RTPKIQEQYRRIGGGSPIKIWTSKQGEGMVKLLDELSPNTAPHKYYIGFRYVHPLTEEAI
120 130 140 150 160 170
190 200 210 220 230 240
pF1KE2 EEMERDGLERAIAFTQYPQYSCSTTGSSLNAIYRYYNQVGRKPTMKWSTIDRWPTHHLLI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EEMERDGLERAIAFTQYPQYSCSTTGSSLNAIYRYYNQVGRKPTMKWSTIDRWPTHHLLI
180 190 200 210 220 230
250 260 270 280 290 300
pF1KE2 QCFADHILKELDHFPLEKRSEVVILFSAHSLPMSVVNRGDPYPQEVSATVQKVMERLEYC
: ::::::::::::::::::::::::::
XP_016 Q---------------------------------VVNRGDPYPQEVSATVQKVMERLEYC
240 250 260
310 320 330 340 350 360
pF1KE2 NPYRLVWQSKVGPMPWLGPQTDESIKGLCERGRKNILLVPIAFTSDHIETLYELDIEYSQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NPYRLVWQSKVGPMPWLGPQTDESIKGLCERGRKNILLVPIAFTSDHIETLYELDIEYSQ
270 280 290 300 310 320
370 380 390 400 410 420
pF1KE2 VLAKECGVENIRRAESLNGNPLFSKALADLVHSHIQSNELCSKQLTLSCPLCVNPVCRET
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VLAKECGVENIRRAESLNGNPLFSKALADLVHSHIQSNELCSKQLTLSCPLCVNPVCRET
330 340 350 360 370 380
pF1KE2 KSFFTSQQL
:::::::::
XP_016 KSFFTSQQL
390
429 residues in 1 query sequences
63214209 residues in 88908 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Mon Sep 11 12:02:29 2017 done: Mon Sep 11 12:02:30 2017
Total Scan time: 7.400 Total Display time: 0.000
Function used was FASTA [36.3.4 Apr, 2011]