Result of FASTA (omim) for
pFN21AE2582
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE2582, 956 aa
1>>>pF1KE2582 956 - 956 aa - 956 aa
Library: /omim/omim.rfq.tfa
65951994 residues in 93482 sequences
Statistics: Expectation_n fit: rho(ln(x))= 12.7056+/-0.000409; mu= -12.6949+/- 0.025
mean_var=385.4133+/-79.635, 0's: 0 Z-trim(122.5): 29 B-trim: 2475 in 2/55
Lambda= 0.065330
statistics sampled from 42602 (42637) to 42602 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.75), E-opt: 0.2 (0.456), width: 16
Scan time: 7.750
The best scores are: opt bits E(93482)
NP_570899 (OMIM: 614657) angiomotin-like protein 1 ( 956) 6310 609.5 2.9e-173
XP_005273855 (OMIM: 614657) angiomotin-like protei ( 985) 6195 598.6 5.5e-170
XP_011540928 (OMIM: 614657) angiomotin-like protei ( 935) 5879 568.8 4.8e-161
NP_001287936 (OMIM: 614657) angiomotin-like protei ( 906) 5870 568.0 8.5e-161
XP_005273858 (OMIM: 614657) angiomotin-like protei ( 870) 5729 554.7 8.2e-157
XP_006718835 (OMIM: 614657) angiomotin-like protei ( 677) 4199 410.4 1.7e-113
XP_011540930 (OMIM: 614657) angiomotin-like protei ( 604) 3783 371.2 9.9e-102
XP_005262144 (OMIM: 300410) angiomotin isoform X1 (1084) 1884 192.3 1.2e-47
NP_001106962 (OMIM: 300410) angiomotin isoform 1 [ (1084) 1884 192.3 1.2e-47
XP_011529177 (OMIM: 300410) angiomotin isoform X1 (1084) 1884 192.3 1.2e-47
XP_005262147 (OMIM: 300410) angiomotin isoform X2 ( 675) 1847 188.7 9.2e-47
XP_016884778 (OMIM: 300410) angiomotin isoform X2 ( 675) 1847 188.7 9.2e-47
NP_573572 (OMIM: 300410) angiomotin isoform 2 [Hom ( 675) 1847 188.7 9.2e-47
NP_001350872 (OMIM: 614658) angiomotin-like protei ( 779) 1306 137.8 2.3e-31
XP_006713717 (OMIM: 614658) angiomotin-like protei ( 779) 1306 137.8 2.3e-31
XP_016862069 (OMIM: 614658) angiomotin-like protei ( 780) 1306 137.8 2.3e-31
XP_016862070 (OMIM: 614658) angiomotin-like protei ( 780) 1306 137.8 2.3e-31
XP_016862071 (OMIM: 614658) angiomotin-like protei ( 780) 1306 137.8 2.3e-31
NP_057285 (OMIM: 614658) angiomotin-like protein 2 ( 780) 1306 137.8 2.3e-31
NP_001265612 (OMIM: 614658) angiomotin-like protei ( 837) 1306 137.8 2.5e-31
NP_001265614 (OMIM: 614658) angiomotin-like protei ( 777) 1303 137.5 2.8e-31
>>NP_570899 (OMIM: 614657) angiomotin-like protein 1 iso (956 aa)
initn: 6310 init1: 6310 opt: 6310 Z-score: 3232.3 bits: 609.5 E(93482): 2.9e-173
Smith-Waterman score: 6310; 100.0% identity (100.0% similar) in 956 aa overlap (1-956:1-956)
10 20 30 40 50 60
pF1KE2 MWRAKLRRGTCEPAVKGSPSACYSPSSPVQVLEDSTYFSPDFQLYSGRHETSALTVEATS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_570 MWRAKLRRGTCEPAVKGSPSACYSPSSPVQVLEDSTYFSPDFQLYSGRHETSALTVEATS
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE2 SIREKVVEDPLCNFHSPNFLRISEVEMRGSEDAAAGTVLQRLIQEQLRYGTPTENMNLLA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_570 SIREKVVEDPLCNFHSPNFLRISEVEMRGSEDAAAGTVLQRLIQEQLRYGTPTENMNLLA
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE2 IQHQATGSAGPAHPTNNFSSTENLTQEDPQMVYQSARQEPQGQEHQVDNTVMEKQVRSTQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_570 IQHQATGSAGPAHPTNNFSSTENLTQEDPQMVYQSARQEPQGQEHQVDNTVMEKQVRSTQ
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE2 PQQNNEELPTYEEAKAQSQFFRGQQQQQQQQGAVGHGYYMAGGTSQKSRTEGRPTVNRAN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_570 PQQNNEELPTYEEAKAQSQFFRGQQQQQQQQGAVGHGYYMAGGTSQKSRTEGRPTVNRAN
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE2 SGQAHKDEALKELKQGHVRSLSERIMQLSLERNGAKQHLPGSGNGKGFKVGGGPSPAQPA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_570 SGQAHKDEALKELKQGHVRSLSERIMQLSLERNGAKQHLPGSGNGKGFKVGGGPSPAQPA
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE2 GKVLDPRGPPPEYPFKTKQMMSPVSKTQEHGLFYGDQHPGMLHEMVKPYPAPQPVRTDVA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_570 GKVLDPRGPPPEYPFKTKQMMSPVSKTQEHGLFYGDQHPGMLHEMVKPYPAPQPVRTDVA
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE2 VLRYQPPPEYGVTSRPCQLPFPSTMQQHSPMSSQTSSASGPLHSVSLPLPLPMALGAPQP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_570 VLRYQPPPEYGVTSRPCQLPFPSTMQQHSPMSSQTSSASGPLHSVSLPLPLPMALGAPQP
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE2 PPAASPSQQLGPDAFAIVERAQQMVEILTEENRVLHQELQGYYDNADKLHKFEKELQRIS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_570 PPAASPSQQLGPDAFAIVERAQQMVEILTEENRVLHQELQGYYDNADKLHKFEKELQRIS
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE2 EAYESLVKSTTKRESLDKAMRNKLEGEIRRLHDFNRDLRDRLETANRQLSSREYEGHEDK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_570 EAYESLVKSTTKRESLDKAMRNKLEGEIRRLHDFNRDLRDRLETANRQLSSREYEGHEDK
490 500 510 520 530 540
550 560 570 580 590 600
pF1KE2 AAEGHYASQNKEFLKEKEKLEMELAAVRTASEDHRRHIEILDQALSNAQARVIKLEEELR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_570 AAEGHYASQNKEFLKEKEKLEMELAAVRTASEDHRRHIEILDQALSNAQARVIKLEEELR
550 560 570 580 590 600
610 620 630 640 650 660
pF1KE2 EKQAYVEKVEKLQQALTQLQSACEKREQMERRLRTWLERELDALRTQQKHGNGQPANMPE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_570 EKQAYVEKVEKLQQALTQLQSACEKREQMERRLRTWLERELDALRTQQKHGNGQPANMPE
610 620 630 640 650 660
670 680 690 700 710 720
pF1KE2 YNAPALLELVREKEERILALEADMTKWEQKYLEESTIRHFAMNAAATAAAERDTTIINHS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_570 YNAPALLELVREKEERILALEADMTKWEQKYLEESTIRHFAMNAAATAAAERDTTIINHS
670 680 690 700 710 720
730 740 750 760 770 780
pF1KE2 RNGSYGESSLEAHIWQEEEEVVQANRRCQDMEYTIKNLHAKIIEKDAMIKVLQQRSRKDA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_570 RNGSYGESSLEAHIWQEEEEVVQANRRCQDMEYTIKNLHAKIIEKDAMIKVLQQRSRKDA
730 740 750 760 770 780
790 800 810 820 830 840
pF1KE2 GKTDSSSLRPARSVPSIAAATGTHSRQTSLTSSQLAEEKKEEKTWKGSIGLLLGKEHHEH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_570 GKTDSSSLRPARSVPSIAAATGTHSRQTSLTSSQLAEEKKEEKTWKGSIGLLLGKEHHEH
790 800 810 820 830 840
850 860 870 880 890 900
pF1KE2 ASAPLLPPPPTSALSSIASTTAASSAHAKTGSKDSSTQTDKSAELFWPSMASLPSRGRLS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_570 ASAPLLPPPPTSALSSIASTTAASSAHAKTGSKDSSTQTDKSAELFWPSMASLPSRGRLS
850 860 870 880 890 900
910 920 930 940 950
pF1KE2 TTPAHSPVLKHPAAKGTAEKLENSPGHGKSPDHRGRVSSLLHKPEFPDGEMMEVLI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_570 TTPAHSPVLKHPAAKGTAEKLENSPGHGKSPDHRGRVSSLLHKPEFPDGEMMEVLI
910 920 930 940 950
>>XP_005273855 (OMIM: 614657) angiomotin-like protein 1 (985 aa)
initn: 6193 init1: 6193 opt: 6195 Z-score: 3173.6 bits: 598.6 E(93482): 5.5e-170
Smith-Waterman score: 6195; 99.7% identity (99.7% similar) in 944 aa overlap (13-956:42-985)
10 20 30 40
pF1KE2 MWRAKLRRGTCEPAVKGSPSACYSPSSPVQVLEDSTYFSPDF
: ::::::::::::::::::::::::::
XP_005 GAWLSHAGIHHFASTRADSEFVEASPASYSPDELGSPSACYSPSSPVQVLEDSTYFSPDF
20 30 40 50 60 70
50 60 70 80 90 100
pF1KE2 QLYSGRHETSALTVEATSSIREKVVEDPLCNFHSPNFLRISEVEMRGSEDAAAGTVLQRL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 QLYSGRHETSALTVEATSSIREKVVEDPLCNFHSPNFLRISEVEMRGSEDAAAGTVLQRL
80 90 100 110 120 130
110 120 130 140 150 160
pF1KE2 IQEQLRYGTPTENMNLLAIQHQATGSAGPAHPTNNFSSTENLTQEDPQMVYQSARQEPQG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 IQEQLRYGTPTENMNLLAIQHQATGSAGPAHPTNNFSSTENLTQEDPQMVYQSARQEPQG
140 150 160 170 180 190
170 180 190 200 210 220
pF1KE2 QEHQVDNTVMEKQVRSTQPQQNNEELPTYEEAKAQSQFFRGQQQQQQQQGAVGHGYYMAG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 QEHQVDNTVMEKQVRSTQPQQNNEELPTYEEAKAQSQFFRGQQQQQQQQGAVGHGYYMAG
200 210 220 230 240 250
230 240 250 260 270 280
pF1KE2 GTSQKSRTEGRPTVNRANSGQAHKDEALKELKQGHVRSLSERIMQLSLERNGAKQHLPGS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 GTSQKSRTEGRPTVNRANSGQAHKDEALKELKQGHVRSLSERIMQLSLERNGAKQHLPGS
260 270 280 290 300 310
290 300 310 320 330 340
pF1KE2 GNGKGFKVGGGPSPAQPAGKVLDPRGPPPEYPFKTKQMMSPVSKTQEHGLFYGDQHPGML
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 GNGKGFKVGGGPSPAQPAGKVLDPRGPPPEYPFKTKQMMSPVSKTQEHGLFYGDQHPGML
320 330 340 350 360 370
350 360 370 380 390 400
pF1KE2 HEMVKPYPAPQPVRTDVAVLRYQPPPEYGVTSRPCQLPFPSTMQQHSPMSSQTSSASGPL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 HEMVKPYPAPQPVRTDVAVLRYQPPPEYGVTSRPCQLPFPSTMQQHSPMSSQTSSASGPL
380 390 400 410 420 430
410 420 430 440 450 460
pF1KE2 HSVSLPLPLPMALGAPQPPPAASPSQQLGPDAFAIVERAQQMVEILTEENRVLHQELQGY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 HSVSLPLPLPMALGAPQPPPAASPSQQLGPDAFAIVERAQQMVEILTEENRVLHQELQGY
440 450 460 470 480 490
470 480 490 500 510 520
pF1KE2 YDNADKLHKFEKELQRISEAYESLVKSTTKRESLDKAMRNKLEGEIRRLHDFNRDLRDRL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 YDNADKLHKFEKELQRISEAYESLVKSTTKRESLDKAMRNKLEGEIRRLHDFNRDLRDRL
500 510 520 530 540 550
530 540 550 560 570 580
pF1KE2 ETANRQLSSREYEGHEDKAAEGHYASQNKEFLKEKEKLEMELAAVRTASEDHRRHIEILD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 ETANRQLSSREYEGHEDKAAEGHYASQNKEFLKEKEKLEMELAAVRTASEDHRRHIEILD
560 570 580 590 600 610
590 600 610 620 630 640
pF1KE2 QALSNAQARVIKLEEELREKQAYVEKVEKLQQALTQLQSACEKREQMERRLRTWLERELD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 QALSNAQARVIKLEEELREKQAYVEKVEKLQQALTQLQSACEKREQMERRLRTWLERELD
620 630 640 650 660 670
650 660 670 680 690 700
pF1KE2 ALRTQQKHGNGQPANMPEYNAPALLELVREKEERILALEADMTKWEQKYLEESTIRHFAM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 ALRTQQKHGNGQPANMPEYNAPALLELVREKEERILALEADMTKWEQKYLEESTIRHFAM
680 690 700 710 720 730
710 720 730 740 750 760
pF1KE2 NAAATAAAERDTTIINHSRNGSYGESSLEAHIWQEEEEVVQANRRCQDMEYTIKNLHAKI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 NAAATAAAERDTTIINHSRNGSYGESSLEAHIWQEEEEVVQANRRCQDMEYTIKNLHAKI
740 750 760 770 780 790
770 780 790 800 810 820
pF1KE2 IEKDAMIKVLQQRSRKDAGKTDSSSLRPARSVPSIAAATGTHSRQTSLTSSQLAEEKKEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 IEKDAMIKVLQQRSRKDAGKTDSSSLRPARSVPSIAAATGTHSRQTSLTSSQLAEEKKEE
800 810 820 830 840 850
830 840 850 860 870 880
pF1KE2 KTWKGSIGLLLGKEHHEHASAPLLPPPPTSALSSIASTTAASSAHAKTGSKDSSTQTDKS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 KTWKGSIGLLLGKEHHEHASAPLLPPPPTSALSSIASTTAASSAHAKTGSKDSSTQTDKS
860 870 880 890 900 910
890 900 910 920 930 940
pF1KE2 AELFWPSMASLPSRGRLSTTPAHSPVLKHPAAKGTAEKLENSPGHGKSPDHRGRVSSLLH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 AELFWPSMASLPSRGRLSTTPAHSPVLKHPAAKGTAEKLENSPGHGKSPDHRGRVSSLLH
920 930 940 950 960 970
950
pF1KE2 KPEFPDGEMMEVLI
::::::::::::::
XP_005 KPEFPDGEMMEVLI
980
>>XP_011540928 (OMIM: 614657) angiomotin-like protein 1 (935 aa)
initn: 5874 init1: 5874 opt: 5879 Z-score: 3012.9 bits: 568.8 E(93482): 4.8e-161
Smith-Waterman score: 5879; 96.7% identity (98.3% similar) in 927 aa overlap (32-956:9-935)
10 20 30 40 50
pF1KE2 WRAKLRRGTCEPAVKGSPSACYSPSSPVQVLEDSTYFSPD--FQLYSGRHETSALTVEAT
::.....: .. : : .. . . .
XP_011 MDLSEKWTLEEGAWLSHAGIHHFASTRADSEFVEASPA
10 20 30
60 70 80 90 100 110
pF1KE2 SSIREKVVEDPLCNFHSPNFLRISEVEMRGSEDAAAGTVLQRLIQEQLRYGTPTENMNLL
: ...:::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SYSPDELVEDPLCNFHSPNFLRISEVEMRGSEDAAAGTVLQRLIQEQLRYGTPTENMNLL
40 50 60 70 80 90
120 130 140 150 160 170
pF1KE2 AIQHQATGSAGPAHPTNNFSSTENLTQEDPQMVYQSARQEPQGQEHQVDNTVMEKQVRST
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AIQHQATGSAGPAHPTNNFSSTENLTQEDPQMVYQSARQEPQGQEHQVDNTVMEKQVRST
100 110 120 130 140 150
180 190 200 210 220 230
pF1KE2 QPQQNNEELPTYEEAKAQSQFFRGQQQQQQQQGAVGHGYYMAGGTSQKSRTEGRPTVNRA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QPQQNNEELPTYEEAKAQSQFFRGQQQQQQQQGAVGHGYYMAGGTSQKSRTEGRPTVNRA
160 170 180 190 200 210
240 250 260 270 280 290
pF1KE2 NSGQAHKDEALKELKQGHVRSLSERIMQLSLERNGAKQHLPGSGNGKGFKVGGGPSPAQP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NSGQAHKDEALKELKQGHVRSLSERIMQLSLERNGAKQHLPGSGNGKGFKVGGGPSPAQP
220 230 240 250 260 270
300 310 320 330 340 350
pF1KE2 AGKVLDPRGPPPEYPFKTKQMMSPVSKTQEHGLFYGDQHPGMLHEMVKPYPAPQPVRTDV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AGKVLDPRGPPPEYPFKTKQMMSPVSKTQEHGLFYGDQHPGMLHEMVKPYPAPQPVRTDV
280 290 300 310 320 330
360 370 380 390 400 410
pF1KE2 AVLRYQPPPEYGVTSRPCQLPFPSTMQQHSPMSSQTSSASGPLHSVSLPLPLPMALGAPQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AVLRYQPPPEYGVTSRPCQLPFPSTMQQHSPMSSQTSSASGPLHSVSLPLPLPMALGAPQ
340 350 360 370 380 390
420 430 440 450 460 470
pF1KE2 PPPAASPSQQLGPDAFAIVERAQQMVEILTEENRVLHQELQGYYDNADKLHKFEKELQRI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PPPAASPSQQLGPDAFAIVERAQQMVEILTEENRVLHQELQGYYDNADKLHKFEKELQRI
400 410 420 430 440 450
480 490 500 510 520 530
pF1KE2 SEAYESLVKSTTKRESLDKAMRNKLEGEIRRLHDFNRDLRDRLETANRQLSSREYEGHED
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SEAYESLVKSTTKRESLDKAMRNKLEGEIRRLHDFNRDLRDRLETANRQLSSREYEGHED
460 470 480 490 500 510
540 550 560 570 580 590
pF1KE2 KAAEGHYASQNKEFLKEKEKLEMELAAVRTASEDHRRHIEILDQALSNAQARVIKLEEEL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KAAEGHYASQNKEFLKEKEKLEMELAAVRTASEDHRRHIEILDQALSNAQARVIKLEEEL
520 530 540 550 560 570
600 610 620 630 640 650
pF1KE2 REKQAYVEKVEKLQQALTQLQSACEKREQMERRLRTWLERELDALRTQQKHGNGQPANMP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 REKQAYVEKVEKLQQALTQLQSACEKREQMERRLRTWLERELDALRTQQKHGNGQPANMP
580 590 600 610 620 630
660 670 680 690 700 710
pF1KE2 EYNAPALLELVREKEERILALEADMTKWEQKYLEESTIRHFAMNAAATAAAERDTTIINH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EYNAPALLELVREKEERILALEADMTKWEQKYLEESTIRHFAMNAAATAAAERDTTIINH
640 650 660 670 680 690
720 730 740 750 760 770
pF1KE2 SRNGSYGESSLEAHIWQEEEEVVQANRRCQDMEYTIKNLHAKIIEKDAMIKVLQQRSRKD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SRNGSYGESSLEAHIWQEEEEVVQANRRCQDMEYTIKNLHAKIIEKDAMIKVLQQRSRKD
700 710 720 730 740 750
780 790 800 810 820 830
pF1KE2 AGKTDSSSLRPARSVPSIAAATGTHSRQTSLTSSQLAEEKKEEKTWKGSIGLLLGKEHHE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AGKTDSSSLRPARSVPSIAAATGTHSRQTSLTSSQLAEEKKEEKTWKGSIGLLLGKEHHE
760 770 780 790 800 810
840 850 860 870 880 890
pF1KE2 HASAPLLPPPPTSALSSIASTTAASSAHAKTGSKDSSTQTDKSAELFWPSMASLPSRGRL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 HASAPLLPPPPTSALSSIASTTAASSAHAKTGSKDSSTQTDKSAELFWPSMASLPSRGRL
820 830 840 850 860 870
900 910 920 930 940 950
pF1KE2 STTPAHSPVLKHPAAKGTAEKLENSPGHGKSPDHRGRVSSLLHKPEFPDGEMMEVLI
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 STTPAHSPVLKHPAAKGTAEKLENSPGHGKSPDHRGRVSSLLHKPEFPDGEMMEVLI
880 890 900 910 920 930
>>NP_001287936 (OMIM: 614657) angiomotin-like protein 1 (906 aa)
initn: 5870 init1: 5870 opt: 5870 Z-score: 3008.5 bits: 568.0 E(93482): 8.5e-161
Smith-Waterman score: 5877; 94.8% identity (94.8% similar) in 956 aa overlap (1-956:1-906)
10 20 30 40 50 60
pF1KE2 MWRAKLRRGTCEPAVKGSPSACYSPSSPVQVLEDSTYFSPDFQLYSGRHETSALTVEATS
::::::::::::::::
NP_001 MWRAKLRRGTCEPAVK--------------------------------------------
10
70 80 90 100 110 120
pF1KE2 SIREKVVEDPLCNFHSPNFLRISEVEMRGSEDAAAGTVLQRLIQEQLRYGTPTENMNLLA
::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ------VEDPLCNFHSPNFLRISEVEMRGSEDAAAGTVLQRLIQEQLRYGTPTENMNLLA
20 30 40 50 60 70
130 140 150 160 170 180
pF1KE2 IQHQATGSAGPAHPTNNFSSTENLTQEDPQMVYQSARQEPQGQEHQVDNTVMEKQVRSTQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IQHQATGSAGPAHPTNNFSSTENLTQEDPQMVYQSARQEPQGQEHQVDNTVMEKQVRSTQ
80 90 100 110 120 130
190 200 210 220 230 240
pF1KE2 PQQNNEELPTYEEAKAQSQFFRGQQQQQQQQGAVGHGYYMAGGTSQKSRTEGRPTVNRAN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PQQNNEELPTYEEAKAQSQFFRGQQQQQQQQGAVGHGYYMAGGTSQKSRTEGRPTVNRAN
140 150 160 170 180 190
250 260 270 280 290 300
pF1KE2 SGQAHKDEALKELKQGHVRSLSERIMQLSLERNGAKQHLPGSGNGKGFKVGGGPSPAQPA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SGQAHKDEALKELKQGHVRSLSERIMQLSLERNGAKQHLPGSGNGKGFKVGGGPSPAQPA
200 210 220 230 240 250
310 320 330 340 350 360
pF1KE2 GKVLDPRGPPPEYPFKTKQMMSPVSKTQEHGLFYGDQHPGMLHEMVKPYPAPQPVRTDVA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GKVLDPRGPPPEYPFKTKQMMSPVSKTQEHGLFYGDQHPGMLHEMVKPYPAPQPVRTDVA
260 270 280 290 300 310
370 380 390 400 410 420
pF1KE2 VLRYQPPPEYGVTSRPCQLPFPSTMQQHSPMSSQTSSASGPLHSVSLPLPLPMALGAPQP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VLRYQPPPEYGVTSRPCQLPFPSTMQQHSPMSSQTSSASGPLHSVSLPLPLPMALGAPQP
320 330 340 350 360 370
430 440 450 460 470 480
pF1KE2 PPAASPSQQLGPDAFAIVERAQQMVEILTEENRVLHQELQGYYDNADKLHKFEKELQRIS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PPAASPSQQLGPDAFAIVERAQQMVEILTEENRVLHQELQGYYDNADKLHKFEKELQRIS
380 390 400 410 420 430
490 500 510 520 530 540
pF1KE2 EAYESLVKSTTKRESLDKAMRNKLEGEIRRLHDFNRDLRDRLETANRQLSSREYEGHEDK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EAYESLVKSTTKRESLDKAMRNKLEGEIRRLHDFNRDLRDRLETANRQLSSREYEGHEDK
440 450 460 470 480 490
550 560 570 580 590 600
pF1KE2 AAEGHYASQNKEFLKEKEKLEMELAAVRTASEDHRRHIEILDQALSNAQARVIKLEEELR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AAEGHYASQNKEFLKEKEKLEMELAAVRTASEDHRRHIEILDQALSNAQARVIKLEEELR
500 510 520 530 540 550
610 620 630 640 650 660
pF1KE2 EKQAYVEKVEKLQQALTQLQSACEKREQMERRLRTWLERELDALRTQQKHGNGQPANMPE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EKQAYVEKVEKLQQALTQLQSACEKREQMERRLRTWLERELDALRTQQKHGNGQPANMPE
560 570 580 590 600 610
670 680 690 700 710 720
pF1KE2 YNAPALLELVREKEERILALEADMTKWEQKYLEESTIRHFAMNAAATAAAERDTTIINHS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 YNAPALLELVREKEERILALEADMTKWEQKYLEESTIRHFAMNAAATAAAERDTTIINHS
620 630 640 650 660 670
730 740 750 760 770 780
pF1KE2 RNGSYGESSLEAHIWQEEEEVVQANRRCQDMEYTIKNLHAKIIEKDAMIKVLQQRSRKDA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RNGSYGESSLEAHIWQEEEEVVQANRRCQDMEYTIKNLHAKIIEKDAMIKVLQQRSRKDA
680 690 700 710 720 730
790 800 810 820 830 840
pF1KE2 GKTDSSSLRPARSVPSIAAATGTHSRQTSLTSSQLAEEKKEEKTWKGSIGLLLGKEHHEH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GKTDSSSLRPARSVPSIAAATGTHSRQTSLTSSQLAEEKKEEKTWKGSIGLLLGKEHHEH
740 750 760 770 780 790
850 860 870 880 890 900
pF1KE2 ASAPLLPPPPTSALSSIASTTAASSAHAKTGSKDSSTQTDKSAELFWPSMASLPSRGRLS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ASAPLLPPPPTSALSSIASTTAASSAHAKTGSKDSSTQTDKSAELFWPSMASLPSRGRLS
800 810 820 830 840 850
910 920 930 940 950
pF1KE2 TTPAHSPVLKHPAAKGTAEKLENSPGHGKSPDHRGRVSSLLHKPEFPDGEMMEVLI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TTPAHSPVLKHPAAKGTAEKLENSPGHGKSPDHRGRVSSLLHKPEFPDGEMMEVLI
860 870 880 890 900
>>XP_005273858 (OMIM: 614657) angiomotin-like protein 1 (870 aa)
initn: 5729 init1: 5729 opt: 5729 Z-score: 2937.0 bits: 554.7 E(93482): 8.2e-157
Smith-Waterman score: 5729; 100.0% identity (100.0% similar) in 870 aa overlap (87-956:1-870)
60 70 80 90 100 110
pF1KE2 EATSSIREKVVEDPLCNFHSPNFLRISEVEMRGSEDAAAGTVLQRLIQEQLRYGTPTENM
::::::::::::::::::::::::::::::
XP_005 MRGSEDAAAGTVLQRLIQEQLRYGTPTENM
10 20 30
120 130 140 150 160 170
pF1KE2 NLLAIQHQATGSAGPAHPTNNFSSTENLTQEDPQMVYQSARQEPQGQEHQVDNTVMEKQV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 NLLAIQHQATGSAGPAHPTNNFSSTENLTQEDPQMVYQSARQEPQGQEHQVDNTVMEKQV
40 50 60 70 80 90
180 190 200 210 220 230
pF1KE2 RSTQPQQNNEELPTYEEAKAQSQFFRGQQQQQQQQGAVGHGYYMAGGTSQKSRTEGRPTV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 RSTQPQQNNEELPTYEEAKAQSQFFRGQQQQQQQQGAVGHGYYMAGGTSQKSRTEGRPTV
100 110 120 130 140 150
240 250 260 270 280 290
pF1KE2 NRANSGQAHKDEALKELKQGHVRSLSERIMQLSLERNGAKQHLPGSGNGKGFKVGGGPSP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 NRANSGQAHKDEALKELKQGHVRSLSERIMQLSLERNGAKQHLPGSGNGKGFKVGGGPSP
160 170 180 190 200 210
300 310 320 330 340 350
pF1KE2 AQPAGKVLDPRGPPPEYPFKTKQMMSPVSKTQEHGLFYGDQHPGMLHEMVKPYPAPQPVR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 AQPAGKVLDPRGPPPEYPFKTKQMMSPVSKTQEHGLFYGDQHPGMLHEMVKPYPAPQPVR
220 230 240 250 260 270
360 370 380 390 400 410
pF1KE2 TDVAVLRYQPPPEYGVTSRPCQLPFPSTMQQHSPMSSQTSSASGPLHSVSLPLPLPMALG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 TDVAVLRYQPPPEYGVTSRPCQLPFPSTMQQHSPMSSQTSSASGPLHSVSLPLPLPMALG
280 290 300 310 320 330
420 430 440 450 460 470
pF1KE2 APQPPPAASPSQQLGPDAFAIVERAQQMVEILTEENRVLHQELQGYYDNADKLHKFEKEL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 APQPPPAASPSQQLGPDAFAIVERAQQMVEILTEENRVLHQELQGYYDNADKLHKFEKEL
340 350 360 370 380 390
480 490 500 510 520 530
pF1KE2 QRISEAYESLVKSTTKRESLDKAMRNKLEGEIRRLHDFNRDLRDRLETANRQLSSREYEG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 QRISEAYESLVKSTTKRESLDKAMRNKLEGEIRRLHDFNRDLRDRLETANRQLSSREYEG
400 410 420 430 440 450
540 550 560 570 580 590
pF1KE2 HEDKAAEGHYASQNKEFLKEKEKLEMELAAVRTASEDHRRHIEILDQALSNAQARVIKLE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 HEDKAAEGHYASQNKEFLKEKEKLEMELAAVRTASEDHRRHIEILDQALSNAQARVIKLE
460 470 480 490 500 510
600 610 620 630 640 650
pF1KE2 EELREKQAYVEKVEKLQQALTQLQSACEKREQMERRLRTWLERELDALRTQQKHGNGQPA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 EELREKQAYVEKVEKLQQALTQLQSACEKREQMERRLRTWLERELDALRTQQKHGNGQPA
520 530 540 550 560 570
660 670 680 690 700 710
pF1KE2 NMPEYNAPALLELVREKEERILALEADMTKWEQKYLEESTIRHFAMNAAATAAAERDTTI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 NMPEYNAPALLELVREKEERILALEADMTKWEQKYLEESTIRHFAMNAAATAAAERDTTI
580 590 600 610 620 630
720 730 740 750 760 770
pF1KE2 INHSRNGSYGESSLEAHIWQEEEEVVQANRRCQDMEYTIKNLHAKIIEKDAMIKVLQQRS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 INHSRNGSYGESSLEAHIWQEEEEVVQANRRCQDMEYTIKNLHAKIIEKDAMIKVLQQRS
640 650 660 670 680 690
780 790 800 810 820 830
pF1KE2 RKDAGKTDSSSLRPARSVPSIAAATGTHSRQTSLTSSQLAEEKKEEKTWKGSIGLLLGKE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 RKDAGKTDSSSLRPARSVPSIAAATGTHSRQTSLTSSQLAEEKKEEKTWKGSIGLLLGKE
700 710 720 730 740 750
840 850 860 870 880 890
pF1KE2 HHEHASAPLLPPPPTSALSSIASTTAASSAHAKTGSKDSSTQTDKSAELFWPSMASLPSR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 HHEHASAPLLPPPPTSALSSIASTTAASSAHAKTGSKDSSTQTDKSAELFWPSMASLPSR
760 770 780 790 800 810
900 910 920 930 940 950
pF1KE2 GRLSTTPAHSPVLKHPAAKGTAEKLENSPGHGKSPDHRGRVSSLLHKPEFPDGEMMEVLI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 GRLSTTPAHSPVLKHPAAKGTAEKLENSPGHGKSPDHRGRVSSLLHKPEFPDGEMMEVLI
820 830 840 850 860 870
>>XP_006718835 (OMIM: 614657) angiomotin-like protein 1 (677 aa)
initn: 4197 init1: 4197 opt: 4199 Z-score: 2159.3 bits: 410.4 E(93482): 1.7e-113
Smith-Waterman score: 4199; 99.5% identity (99.5% similar) in 636 aa overlap (13-648:42-677)
10 20 30 40
pF1KE2 MWRAKLRRGTCEPAVKGSPSACYSPSSPVQVLEDSTYFSPDF
: ::::::::::::::::::::::::::
XP_006 GAWLSHAGIHHFASTRADSEFVEASPASYSPDELGSPSACYSPSSPVQVLEDSTYFSPDF
20 30 40 50 60 70
50 60 70 80 90 100
pF1KE2 QLYSGRHETSALTVEATSSIREKVVEDPLCNFHSPNFLRISEVEMRGSEDAAAGTVLQRL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 QLYSGRHETSALTVEATSSIREKVVEDPLCNFHSPNFLRISEVEMRGSEDAAAGTVLQRL
80 90 100 110 120 130
110 120 130 140 150 160
pF1KE2 IQEQLRYGTPTENMNLLAIQHQATGSAGPAHPTNNFSSTENLTQEDPQMVYQSARQEPQG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 IQEQLRYGTPTENMNLLAIQHQATGSAGPAHPTNNFSSTENLTQEDPQMVYQSARQEPQG
140 150 160 170 180 190
170 180 190 200 210 220
pF1KE2 QEHQVDNTVMEKQVRSTQPQQNNEELPTYEEAKAQSQFFRGQQQQQQQQGAVGHGYYMAG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 QEHQVDNTVMEKQVRSTQPQQNNEELPTYEEAKAQSQFFRGQQQQQQQQGAVGHGYYMAG
200 210 220 230 240 250
230 240 250 260 270 280
pF1KE2 GTSQKSRTEGRPTVNRANSGQAHKDEALKELKQGHVRSLSERIMQLSLERNGAKQHLPGS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 GTSQKSRTEGRPTVNRANSGQAHKDEALKELKQGHVRSLSERIMQLSLERNGAKQHLPGS
260 270 280 290 300 310
290 300 310 320 330 340
pF1KE2 GNGKGFKVGGGPSPAQPAGKVLDPRGPPPEYPFKTKQMMSPVSKTQEHGLFYGDQHPGML
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 GNGKGFKVGGGPSPAQPAGKVLDPRGPPPEYPFKTKQMMSPVSKTQEHGLFYGDQHPGML
320 330 340 350 360 370
350 360 370 380 390 400
pF1KE2 HEMVKPYPAPQPVRTDVAVLRYQPPPEYGVTSRPCQLPFPSTMQQHSPMSSQTSSASGPL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 HEMVKPYPAPQPVRTDVAVLRYQPPPEYGVTSRPCQLPFPSTMQQHSPMSSQTSSASGPL
380 390 400 410 420 430
410 420 430 440 450 460
pF1KE2 HSVSLPLPLPMALGAPQPPPAASPSQQLGPDAFAIVERAQQMVEILTEENRVLHQELQGY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 HSVSLPLPLPMALGAPQPPPAASPSQQLGPDAFAIVERAQQMVEILTEENRVLHQELQGY
440 450 460 470 480 490
470 480 490 500 510 520
pF1KE2 YDNADKLHKFEKELQRISEAYESLVKSTTKRESLDKAMRNKLEGEIRRLHDFNRDLRDRL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 YDNADKLHKFEKELQRISEAYESLVKSTTKRESLDKAMRNKLEGEIRRLHDFNRDLRDRL
500 510 520 530 540 550
530 540 550 560 570 580
pF1KE2 ETANRQLSSREYEGHEDKAAEGHYASQNKEFLKEKEKLEMELAAVRTASEDHRRHIEILD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 ETANRQLSSREYEGHEDKAAEGHYASQNKEFLKEKEKLEMELAAVRTASEDHRRHIEILD
560 570 580 590 600 610
590 600 610 620 630 640
pF1KE2 QALSNAQARVIKLEEELREKQAYVEKVEKLQQALTQLQSACEKREQMERRLRTWLERELD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 QALSNAQARVIKLEEELREKQAYVEKVEKLQQALTQLQSACEKREQMERRLRTWLERELD
620 630 640 650 660 670
650 660 670 680 690 700
pF1KE2 ALRTQQKHGNGQPANMPEYNAPALLELVREKEERILALEADMTKWEQKYLEESTIRHFAM
::::::
XP_006 ALRTQQ
>>XP_011540930 (OMIM: 614657) angiomotin-like protein 1 (604 aa)
initn: 3775 init1: 3775 opt: 3783 Z-score: 1948.1 bits: 371.2 E(93482): 9.9e-102
Smith-Waterman score: 3783; 99.2% identity (99.3% similar) in 591 aa overlap (366-956:15-604)
340 350 360 370 380 390
pF1KE2 DQHPGMLHEMVKPYPAPQPVRTDVAVLRYQPPPEYGVTSRPCQLPFPSTMQQHSPMSSQT
: : : . ::::::::::::::::::::::
XP_011 MHCILCTPQERQLLPWPLY-TPSRPCQLPFPSTMQQHSPMSSQT
10 20 30 40
400 410 420 430 440 450
pF1KE2 SSASGPLHSVSLPLPLPMALGAPQPPPAASPSQQLGPDAFAIVERAQQMVEILTEENRVL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SSASGPLHSVSLPLPLPMALGAPQPPPAASPSQQLGPDAFAIVERAQQMVEILTEENRVL
50 60 70 80 90 100
460 470 480 490 500 510
pF1KE2 HQELQGYYDNADKLHKFEKELQRISEAYESLVKSTTKRESLDKAMRNKLEGEIRRLHDFN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 HQELQGYYDNADKLHKFEKELQRISEAYESLVKSTTKRESLDKAMRNKLEGEIRRLHDFN
110 120 130 140 150 160
520 530 540 550 560 570
pF1KE2 RDLRDRLETANRQLSSREYEGHEDKAAEGHYASQNKEFLKEKEKLEMELAAVRTASEDHR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RDLRDRLETANRQLSSREYEGHEDKAAEGHYASQNKEFLKEKEKLEMELAAVRTASEDHR
170 180 190 200 210 220
580 590 600 610 620 630
pF1KE2 RHIEILDQALSNAQARVIKLEEELREKQAYVEKVEKLQQALTQLQSACEKREQMERRLRT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RHIEILDQALSNAQARVIKLEEELREKQAYVEKVEKLQQALTQLQSACEKREQMERRLRT
230 240 250 260 270 280
640 650 660 670 680 690
pF1KE2 WLERELDALRTQQKHGNGQPANMPEYNAPALLELVREKEERILALEADMTKWEQKYLEES
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 WLERELDALRTQQKHGNGQPANMPEYNAPALLELVREKEERILALEADMTKWEQKYLEES
290 300 310 320 330 340
700 710 720 730 740 750
pF1KE2 TIRHFAMNAAATAAAERDTTIINHSRNGSYGESSLEAHIWQEEEEVVQANRRCQDMEYTI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TIRHFAMNAAATAAAERDTTIINHSRNGSYGESSLEAHIWQEEEEVVQANRRCQDMEYTI
350 360 370 380 390 400
760 770 780 790 800 810
pF1KE2 KNLHAKIIEKDAMIKVLQQRSRKDAGKTDSSSLRPARSVPSIAAATGTHSRQTSLTSSQL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KNLHAKIIEKDAMIKVLQQRSRKDAGKTDSSSLRPARSVPSIAAATGTHSRQTSLTSSQL
410 420 430 440 450 460
820 830 840 850 860 870
pF1KE2 AEEKKEEKTWKGSIGLLLGKEHHEHASAPLLPPPPTSALSSIASTTAASSAHAKTGSKDS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AEEKKEEKTWKGSIGLLLGKEHHEHASAPLLPPPPTSALSSIASTTAASSAHAKTGSKDS
470 480 490 500 510 520
880 890 900 910 920 930
pF1KE2 STQTDKSAELFWPSMASLPSRGRLSTTPAHSPVLKHPAAKGTAEKLENSPGHGKSPDHRG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 STQTDKSAELFWPSMASLPSRGRLSTTPAHSPVLKHPAAKGTAEKLENSPGHGKSPDHRG
530 540 550 560 570 580
940 950
pF1KE2 RVSSLLHKPEFPDGEMMEVLI
:::::::::::::::::::::
XP_011 RVSSLLHKPEFPDGEMMEVLI
590 600
>>XP_005262144 (OMIM: 300410) angiomotin isoform X1 [Hom (1084 aa)
initn: 2374 init1: 862 opt: 1884 Z-score: 977.0 bits: 192.3 E(93482): 1.2e-47
Smith-Waterman score: 2643; 52.5% identity (72.6% similar) in 901 aa overlap (87-884:1-871)
60 70 80 90 100 110
pF1KE2 EATSSIREKVVEDPLCNFHSPNFLRISEVEMRGSEDAAAG--TVLQRLIQEQLRYGTPTE
::.::. .: ::::::.:::::::.:.:
XP_005 MRNSEEQPSGGTTVLQRLLQEQLRYGNPSE
10 20 30
120 130 140 150 160
pF1KE2 NMNLLAIQHQATGSAGPAHPT---NNFSSTENLTQED--PQMVYQSARQEPQGQEHQVDN
: .::::..::::. :: :. : ... :. .: :.: ..::::::::: : .:
XP_005 NRSLLAIHQQATGN-GPPFPSGSGNPGPQSDVLSPQDHHQQLVAHAARQEPQGQEIQSEN
40 50 60 70 80
170 180 190 200 210 220
pF1KE2 TVMEKQVRSTQPQQNNEELPTYEEAKAQSQFFRGQQQQQQQQGAVGHGYYMAGGTSQKSR
.::::. . .:::::::::::::.:::.::::: ...:: ..:..: :.:: :
XP_005 LIMEKQL--SPRMQNNEELPTYEEAKVQSQYFRGQQ-----HASVGAAFYVTGVTNQKMR
90 100 110 120 130 140
230 240 250 260 270 280
pF1KE2 TEGRPTVNRANSGQAHKDEALKELKQGHVRSLSERIMQLSLERNGAKQHLPGSG------
:::::.:.: : :. :.::.:..::::::::::::.::.:: .:.: : : ..
XP_005 TEGRPSVQRLNPGKMHQDEGLRDLKQGHVRSLSERLMQMSLATSGVKAHPPVTSAPLSPP
150 160 170 180 190 200
290 300 310 320 330
pF1KE2 ----------NGKGFKVGGGPSPAQPAGKVLDPRGPPPEYPFKTKQMMSPVSKTQEHGLF
... : . :: : : . : .. :::::::::: .: : : :: : :
XP_005 QPNDLYKNPTSSSEFYKAQGPLPNQHSLKGMEHRGPPPEYPFKGMPPQSVVCKPQEPGHF
210 220 230 240 250 260
340 350 360 370 380
pF1KE2 YGDQHPGMLHEMVKPYPAPQPVRTDVAVLRYQPPPEYGVTSRPCQ---LPFPSTMQQ-HS
:.. :.. :: ::. ..::: :::::. .:: : ::. . .: ::
XP_005 YSE------HRL------NQPGRTEGQLMRYQHPPEYGA-ARPAQDISLPLSARNSQPHS
270 280 290 300
390 400 410
pF1KE2 PMSSQTSSASGPL----------------------HSVSLPLP----LP--------MAL
: :: ::..: :: ::. :: : :: . :
XP_005 PTSSLTSGGSLPLLQSPPSTRLSPARHPLVPNQGDHSAHLPRPQQHFLPNQAHQGDHYRL
310 320 330 340 350 360
420 430
pF1KE2 GAP-------------------------QP---P-------PAASPS----QQLGPDAFA
. : :: : : :.:: : . : ::
XP_005 SQPGLSQQQQQQQQQHHHHHHHQQQQQQQPQQQPGEAYSAMPRAQPSSASYQPVPADPFA
370 380 390 400 410 420
440 450 460 470 480 490
pF1KE2 IVERAQQMVEILTEENRVLHQELQGYYDNADKLHKFEKELQRISEAYESLVKSTTKRESL
:: :::::::::..::: :.:::.: :... .:.: : :.::.:::::.::::..:::.:
XP_005 IVSRAQQMVEILSDENRNLRQELEGCYEKVARLQKVETEIQRVSEAYENLVKSSSKREAL
430 440 450 460 470 480
500 510 520 530 540 550
pF1KE2 DKAMRNKLEGEIRRLHDFNRDLRDRLETANRQLSSREYEGHED-KAAEGHYASQNKEFLK
.:::::::::::::.::::::::.::::::.::. .:::: :: . . .. ..::: .
XP_005 EKAMRNKLEGEIRRMHDFNRDLRERLETANKQLAEKEYEGSEDTRKTISQLFAKNKESQR
490 500 510 520 530 540
560 570 580 590 600 610
pF1KE2 EKEKLEMELAAVRTASEDHRRHIEILDQALSNAQARVIKLEEELREKQAYVEKVEKLQQA
:::::: :::..:...::.:::::: :::::::::.:.::::::..::.::.::::.:::
XP_005 EKEKLEAELATARSTNEDQRRHIEIRDQALSNAQAKVVKLEEELKKKQVYVDKVEKMQQA
550 560 570 580 590 600
620 630 640 650 660 670
pF1KE2 LTQLQSACEKREQMERRLRTWLERELDALRTQQKHGNGQPANMPEYNAPALLELVREKEE
:.:::.:::::::.:.:::: :::::..:: ::..:: ::.:. :::: ::.::.:::::
XP_005 LVQLQAACEKREQLEHRLRTRLERELESLRIQQRQGNCQPTNVSEYNAAALMELLREKEE
610 620 630 640 650 660
680 690 700 710 720 730
pF1KE2 RILALEADMTKWEQKYLEESTIRHFAMNAAATAAAERDTTIINHSRNGSYGESSLEAHIW
:::::::::::::::::::...::::..::::.::.::::.:.:: : :: ...:::.:
XP_005 RILALEADMTKWEQKYLEENVMRHFALDAAATVAAQRDTTVISHSPNTSY-DTALEARIQ
670 680 690 700 710 720
740 750 760 770 780 790
pF1KE2 QEEEEVVQANRRCQDMEYTIKNLHAKIIEKDAMIKVLQQRSRKDAGKTDS-SSLRPARSV
.::::...::.:: ::: ::.:::.:::::::::::::::::. .::.. : .:::.:.
XP_005 KEEEEILMANKRCLDMEGRIKTLHAQIIEKDAMIKVLQQRSRKEPSKTEQLSCMRPAKSL
730 740 750 760 770 780
800 810 820 830 840 850
pF1KE2 PSIA-AATGTHSRQTSLTSSQLAEEKKEEKTWKGSIGLLLGKEHHEHASAPLLPPPPTSA
::. :..: :....::.: . :::...:.::::.:.::: ... : .: :
XP_005 MSISNAGSGLLSHSSTLTGSPIMEEKRDDKSWKGSLGILLGGDYR----AEYVPSTP---
790 800 810 820 830 840
860 870 880 890 900 910
pF1KE2 LSSIASTTAASSAHAKTGSKDSSTQTDKSAELFWPSMASLPSRGRLSTTPAHSPVLKHPA
: . .: :::.::::.: ::::....:
XP_005 -SPVPPSTPLLSAHSKTGSRDCSTQTERGTESNKTAAVAPISVPAPVAAAATAAAITATA
850 860 870 880 890 900
920 930 940 950
pF1KE2 AKGTAEKLENSPGHGKSPDHRGRVSSLLHKPEFPDGEMMEVLI
XP_005 ATITTTMVAAAPVAVAAAAAPAAAAAPSPATAAATAAAVSPAAAGQIPAAASVASAAAVA
910 920 930 940 950 960
>>NP_001106962 (OMIM: 300410) angiomotin isoform 1 [Homo (1084 aa)
initn: 2374 init1: 862 opt: 1884 Z-score: 977.0 bits: 192.3 E(93482): 1.2e-47
Smith-Waterman score: 2643; 52.5% identity (72.6% similar) in 901 aa overlap (87-884:1-871)
60 70 80 90 100 110
pF1KE2 EATSSIREKVVEDPLCNFHSPNFLRISEVEMRGSEDAAAG--TVLQRLIQEQLRYGTPTE
::.::. .: ::::::.:::::::.:.:
NP_001 MRNSEEQPSGGTTVLQRLLQEQLRYGNPSE
10 20 30
120 130 140 150 160
pF1KE2 NMNLLAIQHQATGSAGPAHPT---NNFSSTENLTQED--PQMVYQSARQEPQGQEHQVDN
: .::::..::::. :: :. : ... :. .: :.: ..::::::::: : .:
NP_001 NRSLLAIHQQATGN-GPPFPSGSGNPGPQSDVLSPQDHHQQLVAHAARQEPQGQEIQSEN
40 50 60 70 80
170 180 190 200 210 220
pF1KE2 TVMEKQVRSTQPQQNNEELPTYEEAKAQSQFFRGQQQQQQQQGAVGHGYYMAGGTSQKSR
.::::. . .:::::::::::::.:::.::::: ...:: ..:..: :.:: :
NP_001 LIMEKQL--SPRMQNNEELPTYEEAKVQSQYFRGQQ-----HASVGAAFYVTGVTNQKMR
90 100 110 120 130 140
230 240 250 260 270 280
pF1KE2 TEGRPTVNRANSGQAHKDEALKELKQGHVRSLSERIMQLSLERNGAKQHLPGSG------
:::::.:.: : :. :.::.:..::::::::::::.::.:: .:.: : : ..
NP_001 TEGRPSVQRLNPGKMHQDEGLRDLKQGHVRSLSERLMQMSLATSGVKAHPPVTSAPLSPP
150 160 170 180 190 200
290 300 310 320 330
pF1KE2 ----------NGKGFKVGGGPSPAQPAGKVLDPRGPPPEYPFKTKQMMSPVSKTQEHGLF
... : . :: : : . : .. :::::::::: .: : : :: : :
NP_001 QPNDLYKNPTSSSEFYKAQGPLPNQHSLKGMEHRGPPPEYPFKGMPPQSVVCKPQEPGHF
210 220 230 240 250 260
340 350 360 370 380
pF1KE2 YGDQHPGMLHEMVKPYPAPQPVRTDVAVLRYQPPPEYGVTSRPCQ---LPFPSTMQQ-HS
:.. :.. :: ::. ..::: :::::. .:: : ::. . .: ::
NP_001 YSE------HRL------NQPGRTEGQLMRYQHPPEYGA-ARPAQDISLPLSARNSQPHS
270 280 290 300
390 400 410
pF1KE2 PMSSQTSSASGPL----------------------HSVSLPLP----LP--------MAL
: :: ::..: :: ::. :: : :: . :
NP_001 PTSSLTSGGSLPLLQSPPSTRLSPARHPLVPNQGDHSAHLPRPQQHFLPNQAHQGDHYRL
310 320 330 340 350 360
420 430
pF1KE2 GAP-------------------------QP---P-------PAASPS----QQLGPDAFA
. : :: : : :.:: : . : ::
NP_001 SQPGLSQQQQQQQQQHHHHHHHQQQQQQQPQQQPGEAYSAMPRAQPSSASYQPVPADPFA
370 380 390 400 410 420
440 450 460 470 480 490
pF1KE2 IVERAQQMVEILTEENRVLHQELQGYYDNADKLHKFEKELQRISEAYESLVKSTTKRESL
:: :::::::::..::: :.:::.: :... .:.: : :.::.:::::.::::..:::.:
NP_001 IVSRAQQMVEILSDENRNLRQELEGCYEKVARLQKVETEIQRVSEAYENLVKSSSKREAL
430 440 450 460 470 480
500 510 520 530 540 550
pF1KE2 DKAMRNKLEGEIRRLHDFNRDLRDRLETANRQLSSREYEGHED-KAAEGHYASQNKEFLK
.:::::::::::::.::::::::.::::::.::. .:::: :: . . .. ..::: .
NP_001 EKAMRNKLEGEIRRMHDFNRDLRERLETANKQLAEKEYEGSEDTRKTISQLFAKNKESQR
490 500 510 520 530 540
560 570 580 590 600 610
pF1KE2 EKEKLEMELAAVRTASEDHRRHIEILDQALSNAQARVIKLEEELREKQAYVEKVEKLQQA
:::::: :::..:...::.:::::: :::::::::.:.::::::..::.::.::::.:::
NP_001 EKEKLEAELATARSTNEDQRRHIEIRDQALSNAQAKVVKLEEELKKKQVYVDKVEKMQQA
550 560 570 580 590 600
620 630 640 650 660 670
pF1KE2 LTQLQSACEKREQMERRLRTWLERELDALRTQQKHGNGQPANMPEYNAPALLELVREKEE
:.:::.:::::::.:.:::: :::::..:: ::..:: ::.:. :::: ::.::.:::::
NP_001 LVQLQAACEKREQLEHRLRTRLERELESLRIQQRQGNCQPTNVSEYNAAALMELLREKEE
610 620 630 640 650 660
680 690 700 710 720 730
pF1KE2 RILALEADMTKWEQKYLEESTIRHFAMNAAATAAAERDTTIINHSRNGSYGESSLEAHIW
:::::::::::::::::::...::::..::::.::.::::.:.:: : :: ...:::.:
NP_001 RILALEADMTKWEQKYLEENVMRHFALDAAATVAAQRDTTVISHSPNTSY-DTALEARIQ
670 680 690 700 710 720
740 750 760 770 780 790
pF1KE2 QEEEEVVQANRRCQDMEYTIKNLHAKIIEKDAMIKVLQQRSRKDAGKTDS-SSLRPARSV
.::::...::.:: ::: ::.:::.:::::::::::::::::. .::.. : .:::.:.
NP_001 KEEEEILMANKRCLDMEGRIKTLHAQIIEKDAMIKVLQQRSRKEPSKTEQLSCMRPAKSL
730 740 750 760 770 780
800 810 820 830 840 850
pF1KE2 PSIA-AATGTHSRQTSLTSSQLAEEKKEEKTWKGSIGLLLGKEHHEHASAPLLPPPPTSA
::. :..: :....::.: . :::...:.::::.:.::: ... : .: :
NP_001 MSISNAGSGLLSHSSTLTGSPIMEEKRDDKSWKGSLGILLGGDYR----AEYVPSTP---
790 800 810 820 830 840
860 870 880 890 900 910
pF1KE2 LSSIASTTAASSAHAKTGSKDSSTQTDKSAELFWPSMASLPSRGRLSTTPAHSPVLKHPA
: . .: :::.::::.: ::::....:
NP_001 -SPVPPSTPLLSAHSKTGSRDCSTQTERGTESNKTAAVAPISVPAPVAAAATAAAITATA
850 860 870 880 890 900
920 930 940 950
pF1KE2 AKGTAEKLENSPGHGKSPDHRGRVSSLLHKPEFPDGEMMEVLI
NP_001 ATITTTMVAAAPVAVAAAAAPAAAAAPSPATAAATAAAVSPAAAGQIPAAASVASAAAVA
910 920 930 940 950 960
>>XP_011529177 (OMIM: 300410) angiomotin isoform X1 [Hom (1084 aa)
initn: 2374 init1: 862 opt: 1884 Z-score: 977.0 bits: 192.3 E(93482): 1.2e-47
Smith-Waterman score: 2643; 52.5% identity (72.6% similar) in 901 aa overlap (87-884:1-871)
60 70 80 90 100 110
pF1KE2 EATSSIREKVVEDPLCNFHSPNFLRISEVEMRGSEDAAAG--TVLQRLIQEQLRYGTPTE
::.::. .: ::::::.:::::::.:.:
XP_011 MRNSEEQPSGGTTVLQRLLQEQLRYGNPSE
10 20 30
120 130 140 150 160
pF1KE2 NMNLLAIQHQATGSAGPAHPT---NNFSSTENLTQED--PQMVYQSARQEPQGQEHQVDN
: .::::..::::. :: :. : ... :. .: :.: ..::::::::: : .:
XP_011 NRSLLAIHQQATGN-GPPFPSGSGNPGPQSDVLSPQDHHQQLVAHAARQEPQGQEIQSEN
40 50 60 70 80
170 180 190 200 210 220
pF1KE2 TVMEKQVRSTQPQQNNEELPTYEEAKAQSQFFRGQQQQQQQQGAVGHGYYMAGGTSQKSR
.::::. . .:::::::::::::.:::.::::: ...:: ..:..: :.:: :
XP_011 LIMEKQL--SPRMQNNEELPTYEEAKVQSQYFRGQQ-----HASVGAAFYVTGVTNQKMR
90 100 110 120 130 140
230 240 250 260 270 280
pF1KE2 TEGRPTVNRANSGQAHKDEALKELKQGHVRSLSERIMQLSLERNGAKQHLPGSG------
:::::.:.: : :. :.::.:..::::::::::::.::.:: .:.: : : ..
XP_011 TEGRPSVQRLNPGKMHQDEGLRDLKQGHVRSLSERLMQMSLATSGVKAHPPVTSAPLSPP
150 160 170 180 190 200
290 300 310 320 330
pF1KE2 ----------NGKGFKVGGGPSPAQPAGKVLDPRGPPPEYPFKTKQMMSPVSKTQEHGLF
... : . :: : : . : .. :::::::::: .: : : :: : :
XP_011 QPNDLYKNPTSSSEFYKAQGPLPNQHSLKGMEHRGPPPEYPFKGMPPQSVVCKPQEPGHF
210 220 230 240 250 260
340 350 360 370 380
pF1KE2 YGDQHPGMLHEMVKPYPAPQPVRTDVAVLRYQPPPEYGVTSRPCQ---LPFPSTMQQ-HS
:.. :.. :: ::. ..::: :::::. .:: : ::. . .: ::
XP_011 YSE------HRL------NQPGRTEGQLMRYQHPPEYGA-ARPAQDISLPLSARNSQPHS
270 280 290 300
390 400 410
pF1KE2 PMSSQTSSASGPL----------------------HSVSLPLP----LP--------MAL
: :: ::..: :: ::. :: : :: . :
XP_011 PTSSLTSGGSLPLLQSPPSTRLSPARHPLVPNQGDHSAHLPRPQQHFLPNQAHQGDHYRL
310 320 330 340 350 360
420 430
pF1KE2 GAP-------------------------QP---P-------PAASPS----QQLGPDAFA
. : :: : : :.:: : . : ::
XP_011 SQPGLSQQQQQQQQQHHHHHHHQQQQQQQPQQQPGEAYSAMPRAQPSSASYQPVPADPFA
370 380 390 400 410 420
440 450 460 470 480 490
pF1KE2 IVERAQQMVEILTEENRVLHQELQGYYDNADKLHKFEKELQRISEAYESLVKSTTKRESL
:: :::::::::..::: :.:::.: :... .:.: : :.::.:::::.::::..:::.:
XP_011 IVSRAQQMVEILSDENRNLRQELEGCYEKVARLQKVETEIQRVSEAYENLVKSSSKREAL
430 440 450 460 470 480
500 510 520 530 540 550
pF1KE2 DKAMRNKLEGEIRRLHDFNRDLRDRLETANRQLSSREYEGHED-KAAEGHYASQNKEFLK
.:::::::::::::.::::::::.::::::.::. .:::: :: . . .. ..::: .
XP_011 EKAMRNKLEGEIRRMHDFNRDLRERLETANKQLAEKEYEGSEDTRKTISQLFAKNKESQR
490 500 510 520 530 540
560 570 580 590 600 610
pF1KE2 EKEKLEMELAAVRTASEDHRRHIEILDQALSNAQARVIKLEEELREKQAYVEKVEKLQQA
:::::: :::..:...::.:::::: :::::::::.:.::::::..::.::.::::.:::
XP_011 EKEKLEAELATARSTNEDQRRHIEIRDQALSNAQAKVVKLEEELKKKQVYVDKVEKMQQA
550 560 570 580 590 600
620 630 640 650 660 670
pF1KE2 LTQLQSACEKREQMERRLRTWLERELDALRTQQKHGNGQPANMPEYNAPALLELVREKEE
:.:::.:::::::.:.:::: :::::..:: ::..:: ::.:. :::: ::.::.:::::
XP_011 LVQLQAACEKREQLEHRLRTRLERELESLRIQQRQGNCQPTNVSEYNAAALMELLREKEE
610 620 630 640 650 660
680 690 700 710 720 730
pF1KE2 RILALEADMTKWEQKYLEESTIRHFAMNAAATAAAERDTTIINHSRNGSYGESSLEAHIW
:::::::::::::::::::...::::..::::.::.::::.:.:: : :: ...:::.:
XP_011 RILALEADMTKWEQKYLEENVMRHFALDAAATVAAQRDTTVISHSPNTSY-DTALEARIQ
670 680 690 700 710 720
740 750 760 770 780 790
pF1KE2 QEEEEVVQANRRCQDMEYTIKNLHAKIIEKDAMIKVLQQRSRKDAGKTDS-SSLRPARSV
.::::...::.:: ::: ::.:::.:::::::::::::::::. .::.. : .:::.:.
XP_011 KEEEEILMANKRCLDMEGRIKTLHAQIIEKDAMIKVLQQRSRKEPSKTEQLSCMRPAKSL
730 740 750 760 770 780
800 810 820 830 840 850
pF1KE2 PSIA-AATGTHSRQTSLTSSQLAEEKKEEKTWKGSIGLLLGKEHHEHASAPLLPPPPTSA
::. :..: :....::.: . :::...:.::::.:.::: ... : .: :
XP_011 MSISNAGSGLLSHSSTLTGSPIMEEKRDDKSWKGSLGILLGGDYR----AEYVPSTP---
790 800 810 820 830 840
860 870 880 890 900 910
pF1KE2 LSSIASTTAASSAHAKTGSKDSSTQTDKSAELFWPSMASLPSRGRLSTTPAHSPVLKHPA
: . .: :::.::::.: ::::....:
XP_011 -SPVPPSTPLLSAHSKTGSRDCSTQTERGTESNKTAAVAPISVPAPVAAAATAAAITATA
850 860 870 880 890 900
920 930 940 950
pF1KE2 AKGTAEKLENSPGHGKSPDHRGRVSSLLHKPEFPDGEMMEVLI
XP_011 ATITTTMVAAAPVAVAAAAAPAAAAAPSPATAAATAAAVSPAAAGQIPAAASVASAAAVA
910 920 930 940 950 960
956 residues in 1 query sequences
65951994 residues in 93482 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Thu Jun 20 10:39:42 2019 done: Thu Jun 20 10:39:44 2019
Total Scan time: 7.750 Total Display time: 0.220
Function used was FASTA [36.3.4 Apr, 2011]