Result of FASTA (omim) for
pFN21AE3221
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE3221, 501 aa
1>>>pF1KE3221 501 - 501 aa - 501 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 6.9918+/-0.000366; mu= 11.0742+/- 0.023
mean_var=194.7742+/-42.779, 0's: 0 Z-trim(117.5): 266 B-trim: 0 in 0/54
Lambda= 0.091899
statistics sampled from 29225 (29582) to 29225 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.708), E-opt: 0.2 (0.347), width: 16
Scan time: 10.360
The best scores are: opt bits E(85289)
NP_848659 (OMIM: 615563) nuclear receptor-binding ( 501) 3387 462.1 1.7e-129
XP_016868871 (OMIM: 615563) PREDICTED: nuclear rec ( 574) 3131 428.2 3e-119
XP_016868869 (OMIM: 615563) PREDICTED: nuclear rec ( 606) 3131 428.3 3.1e-119
XP_016868867 (OMIM: 615563) PREDICTED: nuclear rec ( 661) 3131 428.3 3.3e-119
XP_016868872 (OMIM: 615563) PREDICTED: nuclear rec ( 557) 3127 427.7 4.2e-119
XP_016868868 (OMIM: 615563) PREDICTED: nuclear rec ( 612) 3127 427.8 4.5e-119
XP_016868870 (OMIM: 615563) PREDICTED: nuclear rec ( 593) 2996 410.4 7.4e-114
NP_001308287 (OMIM: 606010) nuclear receptor-bindi ( 543) 2029 282.1 2.8e-75
NP_001308288 (OMIM: 606010) nuclear receptor-bindi ( 543) 2029 282.1 2.8e-75
NP_001308290 (OMIM: 606010) nuclear receptor-bindi ( 542) 2012 279.9 1.3e-74
NP_001308286 (OMIM: 606010) nuclear receptor-bindi ( 535) 1958 272.7 1.9e-72
NP_037524 (OMIM: 606010) nuclear receptor-binding ( 535) 1958 272.7 1.9e-72
NP_001308291 (OMIM: 606010) nuclear receptor-bindi ( 534) 1949 271.5 4.2e-72
NP_001308292 (OMIM: 606010) nuclear receptor-bindi ( 503) 1480 209.3 2.1e-53
XP_016870544 (OMIM: 606249) PREDICTED: serine/thre (2162) 467 75.7 1.5e-12
XP_016870543 (OMIM: 606249) PREDICTED: serine/thre (2163) 467 75.7 1.5e-12
XP_005252201 (OMIM: 606249) PREDICTED: serine/thre (2185) 467 75.7 1.5e-12
XP_011517238 (OMIM: 606249) PREDICTED: serine/thre (2190) 467 75.7 1.5e-12
XP_011517237 (OMIM: 606249) PREDICTED: serine/thre (2205) 467 75.7 1.5e-12
XP_016870542 (OMIM: 606249) PREDICTED: serine/thre (2208) 467 75.7 1.5e-12
XP_016870541 (OMIM: 606249) PREDICTED: serine/thre (2209) 467 75.7 1.5e-12
XP_016870540 (OMIM: 606249) PREDICTED: serine/thre (2215) 467 75.7 1.5e-12
XP_005252198 (OMIM: 606249) PREDICTED: serine/thre (2217) 467 75.7 1.5e-12
NP_006639 (OMIM: 606249) serine/threonine-protein (2217) 467 75.7 1.5e-12
XP_005252197 (OMIM: 606249) PREDICTED: serine/thre (2224) 467 75.8 1.5e-12
XP_016870539 (OMIM: 606249) PREDICTED: serine/thre (2226) 467 75.8 1.5e-12
XP_016870538 (OMIM: 606249) PREDICTED: serine/thre (2227) 467 75.8 1.5e-12
XP_016870537 (OMIM: 606249) PREDICTED: serine/thre (2241) 467 75.8 1.5e-12
XP_016870536 (OMIM: 606249) PREDICTED: serine/thre (2242) 467 75.8 1.5e-12
XP_011517234 (OMIM: 606249) PREDICTED: serine/thre (2252) 467 75.8 1.5e-12
XP_011517233 (OMIM: 606249) PREDICTED: serine/thre (2254) 467 75.8 1.5e-12
XP_016870535 (OMIM: 606249) PREDICTED: serine/thre (2256) 467 75.8 1.5e-12
XP_011517232 (OMIM: 606249) PREDICTED: serine/thre (2257) 467 75.8 1.5e-12
XP_016870534 (OMIM: 606249) PREDICTED: serine/thre (2259) 467 75.8 1.5e-12
XP_005252194 (OMIM: 606249) PREDICTED: serine/thre (2260) 467 75.8 1.5e-12
XP_011517231 (OMIM: 606249) PREDICTED: serine/thre (2269) 467 75.8 1.5e-12
XP_011517230 (OMIM: 606249) PREDICTED: serine/thre (2284) 467 75.8 1.5e-12
NP_001269323 (OMIM: 606249) serine/threonine-prote (2297) 467 75.8 1.5e-12
XP_011517229 (OMIM: 606249) PREDICTED: serine/thre (2301) 467 75.8 1.5e-12
XP_011517228 (OMIM: 606249) PREDICTED: serine/thre (2302) 467 75.8 1.5e-12
XP_006724656 (OMIM: 300358) PREDICTED: serine/thre (1743) 450 73.4 6.1e-12
NP_001002838 (OMIM: 300358) serine/threonine-prote (1743) 450 73.4 6.1e-12
XP_011529104 (OMIM: 300358) PREDICTED: serine/thre (1753) 450 73.4 6.1e-12
XP_016885234 (OMIM: 300358) PREDICTED: serine/thre (1790) 450 73.4 6.2e-12
XP_016885231 (OMIM: 300358) PREDICTED: serine/thre (1800) 450 73.4 6.2e-12
XP_016885232 (OMIM: 300358) PREDICTED: serine/thre (1800) 450 73.4 6.2e-12
XP_016885233 (OMIM: 300358) PREDICTED: serine/thre (1800) 450 73.4 6.2e-12
XP_016885230 (OMIM: 300358) PREDICTED: serine/thre (1800) 450 73.4 6.2e-12
NP_065973 (OMIM: 300358) serine/threonine-protein (1800) 450 73.4 6.2e-12
XP_016875328 (OMIM: 201300,605232,614492) PREDICTE (2043) 443 72.5 1.3e-11
>>NP_848659 (OMIM: 615563) nuclear receptor-binding prot (501 aa)
initn: 3387 init1: 3387 opt: 3387 Z-score: 2446.1 bits: 462.1 E(85289): 1.7e-129
Smith-Waterman score: 3387; 100.0% identity (100.0% similar) in 501 aa overlap (1-501:1-501)
10 20 30 40 50 60
pF1KE3 MAAPEPAPRRAREREREREDESEDESDILEESPCGRWQKRREQVNQGNMPGLQSTFLAMD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_848 MAAPEPAPRRAREREREREDESEDESDILEESPCGRWQKRREQVNQGNMPGLQSTFLAMD
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE3 TEEGVEVVWNELHFGDRKAFAAHEEKIQTVFEQLVLVDHPNIVKLHKYWLDTSEACARVI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_848 TEEGVEVVWNELHFGDRKAFAAHEEKIQTVFEQLVLVDHPNIVKLHKYWLDTSEACARVI
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE3 FITEYVSSGSLKQFLKKTKKNHKAMNARAWKRWCTQILSALSFLHACSPPIIHGNLTSDT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_848 FITEYVSSGSLKQFLKKTKKNHKAMNARAWKRWCTQILSALSFLHACSPPIIHGNLTSDT
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE3 IFIQHNGLIKIGSVWHRIFSNALPDDLRSPIRAEREELRNLHFFPPEYGEVADGTAVDIF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_848 IFIQHNGLIKIGSVWHRIFSNALPDDLRSPIRAEREELRNLHFFPPEYGEVADGTAVDIF
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE3 SFGMCALEMAVLEIQTNGDTRVTEEAIARARHSLSDPNMREFILCCLARDPARRPSAHSL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_848 SFGMCALEMAVLEIQTNGDTRVTEEAIARARHSLSDPNMREFILCCLARDPARRPSAHSL
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE3 LFHRVLFEVHSLKLLAAHCFIQHQYLMPENVVEEKTKAMDLHAVLAELPRPRRPPLQWRY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_848 LFHRVLFEVHSLKLLAAHCFIQHQYLMPENVVEEKTKAMDLHAVLAELPRPRRPPLQWRY
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE3 SEVSFMELDKFLEDVRNGIYPLMNFAATRPLGLPRVLAPPPEEVQKAKTPTPEPFDSETR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_848 SEVSFMELDKFLEDVRNGIYPLMNFAATRPLGLPRVLAPPPEEVQKAKTPTPEPFDSETR
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE3 KVIQMQCNLERSEDKARWHLTLLLVLEDRLHRQLTYDLLPTDSAQDLASELVHYGFLHED
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_848 KVIQMQCNLERSEDKARWHLTLLLVLEDRLHRQLTYDLLPTDSAQDLASELVHYGFLHED
430 440 450 460 470 480
490 500
pF1KE3 DRMKLAAFLESTFLKYRGTQA
:::::::::::::::::::::
NP_848 DRMKLAAFLESTFLKYRGTQA
490 500
>>XP_016868871 (OMIM: 615563) PREDICTED: nuclear recepto (574 aa)
initn: 3336 init1: 3126 opt: 3131 Z-score: 2262.0 bits: 428.2 E(85289): 3e-119
Smith-Waterman score: 3131; 97.5% identity (98.5% similar) in 475 aa overlap (1-475:1-475)
10 20 30 40 50 60
pF1KE3 MAAPEPAPRRAREREREREDESEDESDILEESPCGRWQKRREQVNQGNMPGLQSTFLAMD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MAAPEPAPRRAREREREREDESEDESDILEESPCGRWQKRREQVNQGNMPGLQSTFLAMD
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE3 TEEGVEVVWNELHFGDRKAFAAHEEKIQTVFEQLVLVDHPNIVKLHKYWLDTSEACARVI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TEEGVEVVWNELHFGDRKAFAAHEEKIQTVFEQLVLVDHPNIVKLHKYWLDTSEACARVI
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE3 FITEYVSSGSLKQFLKKTKKNHKAMNARAWKRWCTQILSALSFLHACSPPIIHGNLTSDT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FITEYVSSGSLKQFLKKTKKNHKAMNARAWKRWCTQILSALSFLHACSPPIIHGNLTSDT
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE3 IFIQHNGLIKIGSVWHRIFSNALPDDLRSPIRAEREELRNLHFFPPEYGEVADGTAVDIF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IFIQHNGLIKIGSVWHRIFSNALPDDLRSPIRAEREELRNLHFFPPEYGEVADGTAVDIF
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE3 SFGMCALEMAVLEIQTNGDTRVTEEAIARARHSLSDPNMREFILCCLARDPARRPSAHSL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SFGMCALEMAVLEIQTNGDTRVTEEAIARARHSLSDPNMREFILCCLARDPARRPSAHSL
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE3 LFHRVLFEVHSLKLLAAHCFIQHQYLMPENVVEEKTKAMDLHAVLAELPRPRRPPLQWRY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LFHRVLFEVHSLKLLAAHCFIQHQYLMPENVVEEKTKAMDLHAVLAELPRPRRPPLQWRY
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE3 SEVSFMELDKFLEDVRNGIYPLMNFAATRPLGLPRVLAPPPEEVQKAKTPTPEPFDSETR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SEVSFMELDKFLEDVRNGIYPLMNFAATRPLGLPRVLAPPPEEVQKAKTPTPEPFDSETR
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE3 KVIQMQCNLERSEDKARWHLTLLLVLEDRLHRQLTYDLLPTDSAQDLASELVHYGFLHED
::::::::::::::::::::::::::::::::::::::::. .. :. . : :
XP_016 KVIQMQCNLERSEDKARWHLTLLLVLEDRLHRQLTYDLLPSRLGRGLGRRAVTPGGGWAA
430 440 450 460 470 480
490 500
pF1KE3 DRMKLAAFLESTFLKYRGTQA
XP_016 ASCLALRHCLSGQRPGPRLGARALWLPPRGRPDEAGRLPGEHLPQVPWDPGLTRSPSPRG
490 500 510 520 530 540
>>XP_016868869 (OMIM: 615563) PREDICTED: nuclear recepto (606 aa)
initn: 3336 init1: 3126 opt: 3131 Z-score: 2261.7 bits: 428.3 E(85289): 3.1e-119
Smith-Waterman score: 3131; 97.5% identity (98.5% similar) in 475 aa overlap (1-475:1-475)
10 20 30 40 50 60
pF1KE3 MAAPEPAPRRAREREREREDESEDESDILEESPCGRWQKRREQVNQGNMPGLQSTFLAMD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MAAPEPAPRRAREREREREDESEDESDILEESPCGRWQKRREQVNQGNMPGLQSTFLAMD
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE3 TEEGVEVVWNELHFGDRKAFAAHEEKIQTVFEQLVLVDHPNIVKLHKYWLDTSEACARVI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TEEGVEVVWNELHFGDRKAFAAHEEKIQTVFEQLVLVDHPNIVKLHKYWLDTSEACARVI
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE3 FITEYVSSGSLKQFLKKTKKNHKAMNARAWKRWCTQILSALSFLHACSPPIIHGNLTSDT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FITEYVSSGSLKQFLKKTKKNHKAMNARAWKRWCTQILSALSFLHACSPPIIHGNLTSDT
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE3 IFIQHNGLIKIGSVWHRIFSNALPDDLRSPIRAEREELRNLHFFPPEYGEVADGTAVDIF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IFIQHNGLIKIGSVWHRIFSNALPDDLRSPIRAEREELRNLHFFPPEYGEVADGTAVDIF
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE3 SFGMCALEMAVLEIQTNGDTRVTEEAIARARHSLSDPNMREFILCCLARDPARRPSAHSL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SFGMCALEMAVLEIQTNGDTRVTEEAIARARHSLSDPNMREFILCCLARDPARRPSAHSL
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE3 LFHRVLFEVHSLKLLAAHCFIQHQYLMPENVVEEKTKAMDLHAVLAELPRPRRPPLQWRY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LFHRVLFEVHSLKLLAAHCFIQHQYLMPENVVEEKTKAMDLHAVLAELPRPRRPPLQWRY
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE3 SEVSFMELDKFLEDVRNGIYPLMNFAATRPLGLPRVLAPPPEEVQKAKTPTPEPFDSETR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SEVSFMELDKFLEDVRNGIYPLMNFAATRPLGLPRVLAPPPEEVQKAKTPTPEPFDSETR
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE3 KVIQMQCNLERSEDKARWHLTLLLVLEDRLHRQLTYDLLPTDSAQDLASELVHYGFLHED
::::::::::::::::::::::::::::::::::::::::. .. :. . : :
XP_016 KVIQMQCNLERSEDKARWHLTLLLVLEDRLHRQLTYDLLPSRLGRGLGRRAVTPGGGWAA
430 440 450 460 470 480
490 500
pF1KE3 DRMKLAAFLESTFLKYRGTQA
XP_016 ASCLALRHCLSGQRPGPRLGARALWLPPRGRPDEAGRLPGEHLPQVPWDPGLTRSPSPRG
490 500 510 520 530 540
>>XP_016868867 (OMIM: 615563) PREDICTED: nuclear recepto (661 aa)
initn: 3336 init1: 3126 opt: 3131 Z-score: 2261.2 bits: 428.3 E(85289): 3.3e-119
Smith-Waterman score: 3131; 97.5% identity (98.5% similar) in 475 aa overlap (1-475:1-475)
10 20 30 40 50 60
pF1KE3 MAAPEPAPRRAREREREREDESEDESDILEESPCGRWQKRREQVNQGNMPGLQSTFLAMD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MAAPEPAPRRAREREREREDESEDESDILEESPCGRWQKRREQVNQGNMPGLQSTFLAMD
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE3 TEEGVEVVWNELHFGDRKAFAAHEEKIQTVFEQLVLVDHPNIVKLHKYWLDTSEACARVI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TEEGVEVVWNELHFGDRKAFAAHEEKIQTVFEQLVLVDHPNIVKLHKYWLDTSEACARVI
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE3 FITEYVSSGSLKQFLKKTKKNHKAMNARAWKRWCTQILSALSFLHACSPPIIHGNLTSDT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FITEYVSSGSLKQFLKKTKKNHKAMNARAWKRWCTQILSALSFLHACSPPIIHGNLTSDT
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE3 IFIQHNGLIKIGSVWHRIFSNALPDDLRSPIRAEREELRNLHFFPPEYGEVADGTAVDIF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IFIQHNGLIKIGSVWHRIFSNALPDDLRSPIRAEREELRNLHFFPPEYGEVADGTAVDIF
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE3 SFGMCALEMAVLEIQTNGDTRVTEEAIARARHSLSDPNMREFILCCLARDPARRPSAHSL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SFGMCALEMAVLEIQTNGDTRVTEEAIARARHSLSDPNMREFILCCLARDPARRPSAHSL
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE3 LFHRVLFEVHSLKLLAAHCFIQHQYLMPENVVEEKTKAMDLHAVLAELPRPRRPPLQWRY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LFHRVLFEVHSLKLLAAHCFIQHQYLMPENVVEEKTKAMDLHAVLAELPRPRRPPLQWRY
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE3 SEVSFMELDKFLEDVRNGIYPLMNFAATRPLGLPRVLAPPPEEVQKAKTPTPEPFDSETR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SEVSFMELDKFLEDVRNGIYPLMNFAATRPLGLPRVLAPPPEEVQKAKTPTPEPFDSETR
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE3 KVIQMQCNLERSEDKARWHLTLLLVLEDRLHRQLTYDLLPTDSAQDLASELVHYGFLHED
::::::::::::::::::::::::::::::::::::::::. .. :. . : :
XP_016 KVIQMQCNLERSEDKARWHLTLLLVLEDRLHRQLTYDLLPSRLGRGLGRRAVTPGGGWAA
430 440 450 460 470 480
490 500
pF1KE3 DRMKLAAFLESTFLKYRGTQA
XP_016 ASCLALRHCLSGQRPGPRLGARALWLPPRGRPDEAGRLPGEHLPQVPWDPGLTRSPSPRG
490 500 510 520 530 540
>>XP_016868872 (OMIM: 615563) PREDICTED: nuclear recepto (557 aa)
initn: 3124 init1: 3124 opt: 3127 Z-score: 2259.2 bits: 427.7 E(85289): 4.2e-119
Smith-Waterman score: 3127; 98.3% identity (98.5% similar) in 472 aa overlap (1-470:1-472)
10 20 30 40 50 60
pF1KE3 MAAPEPAPRRAREREREREDESEDESDILEESPCGRWQKRREQVNQGNMPGLQSTFLAMD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MAAPEPAPRRAREREREREDESEDESDILEESPCGRWQKRREQVNQGNMPGLQSTFLAMD
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE3 TEEGVEVVWNELHFGDRKAFAAHEEKIQTVFEQLVLVDHPNIVKLHKYWLDTSEACARVI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TEEGVEVVWNELHFGDRKAFAAHEEKIQTVFEQLVLVDHPNIVKLHKYWLDTSEACARVI
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE3 FITEYVSSGSLKQFLKKTKKNHKAMNARAWKRWCTQILSALSFLHACSPPIIHGNLTSDT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FITEYVSSGSLKQFLKKTKKNHKAMNARAWKRWCTQILSALSFLHACSPPIIHGNLTSDT
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE3 IFIQHNGLIKIGSVWHRIFSNALPDDLRSPIRAEREELRNLHFFPPEYGEVADGTAVDIF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IFIQHNGLIKIGSVWHRIFSNALPDDLRSPIRAEREELRNLHFFPPEYGEVADGTAVDIF
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE3 SFGMCALEMAVLEIQTNGDTRVTEEAIARARHSLSDPNMREFILCCLARDPARRPSAHSL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SFGMCALEMAVLEIQTNGDTRVTEEAIARARHSLSDPNMREFILCCLARDPARRPSAHSL
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE3 LFHRVLFEVHSLKLLAAHCFIQHQYLMPENVVEEKTKAMDLHAVLAELPRPRRPPLQWRY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LFHRVLFEVHSLKLLAAHCFIQHQYLMPENVVEEKTKAMDLHAVLAELPRPRRPPLQWRY
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE3 SEVSFMELDKFLEDVRNGIYPLMNFAATRPLGLPRVLAPPPEEVQKAKTPTPEPFDSETR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SEVSFMELDKFLEDVRNGIYPLMNFAATRPLGLPRVLAPPPEEVQKAKTPTPEPFDSETR
370 380 390 400 410 420
430 440 450 460 470
pF1KE3 KVIQMQCNLERSEDKARWHLTLLLVLEDRLHRQLTYDLLPT--DSAQDLASELVHYGFLH
:::::::::::::::::::::::::::::::::::::::: : : : .:
XP_016 KVIQMQCNLERSEDKARWHLTLLLVLEDRLHRQLTYDLLPRRPDEAGRLPGEHLPQVPWD
430 440 450 460 470 480
480 490 500
pF1KE3 EDDRMKLAAFLESTFLKYRGTQA
XP_016 PGLTRSPSPRGPCRGAAWAGHVGETPAPWGCPPPCAWEHKGPGSEGTPRLLRVGLTLPWA
490 500 510 520 530 540
>>XP_016868868 (OMIM: 615563) PREDICTED: nuclear recepto (612 aa)
initn: 3124 init1: 3124 opt: 3127 Z-score: 2258.8 bits: 427.8 E(85289): 4.5e-119
Smith-Waterman score: 3127; 98.3% identity (98.5% similar) in 472 aa overlap (1-470:1-472)
10 20 30 40 50 60
pF1KE3 MAAPEPAPRRAREREREREDESEDESDILEESPCGRWQKRREQVNQGNMPGLQSTFLAMD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MAAPEPAPRRAREREREREDESEDESDILEESPCGRWQKRREQVNQGNMPGLQSTFLAMD
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE3 TEEGVEVVWNELHFGDRKAFAAHEEKIQTVFEQLVLVDHPNIVKLHKYWLDTSEACARVI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TEEGVEVVWNELHFGDRKAFAAHEEKIQTVFEQLVLVDHPNIVKLHKYWLDTSEACARVI
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE3 FITEYVSSGSLKQFLKKTKKNHKAMNARAWKRWCTQILSALSFLHACSPPIIHGNLTSDT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FITEYVSSGSLKQFLKKTKKNHKAMNARAWKRWCTQILSALSFLHACSPPIIHGNLTSDT
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE3 IFIQHNGLIKIGSVWHRIFSNALPDDLRSPIRAEREELRNLHFFPPEYGEVADGTAVDIF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IFIQHNGLIKIGSVWHRIFSNALPDDLRSPIRAEREELRNLHFFPPEYGEVADGTAVDIF
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE3 SFGMCALEMAVLEIQTNGDTRVTEEAIARARHSLSDPNMREFILCCLARDPARRPSAHSL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SFGMCALEMAVLEIQTNGDTRVTEEAIARARHSLSDPNMREFILCCLARDPARRPSAHSL
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE3 LFHRVLFEVHSLKLLAAHCFIQHQYLMPENVVEEKTKAMDLHAVLAELPRPRRPPLQWRY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LFHRVLFEVHSLKLLAAHCFIQHQYLMPENVVEEKTKAMDLHAVLAELPRPRRPPLQWRY
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE3 SEVSFMELDKFLEDVRNGIYPLMNFAATRPLGLPRVLAPPPEEVQKAKTPTPEPFDSETR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SEVSFMELDKFLEDVRNGIYPLMNFAATRPLGLPRVLAPPPEEVQKAKTPTPEPFDSETR
370 380 390 400 410 420
430 440 450 460 470
pF1KE3 KVIQMQCNLERSEDKARWHLTLLLVLEDRLHRQLTYDLLPT--DSAQDLASELVHYGFLH
:::::::::::::::::::::::::::::::::::::::: : : : .:
XP_016 KVIQMQCNLERSEDKARWHLTLLLVLEDRLHRQLTYDLLPRRPDEAGRLPGEHLPQVPWD
430 440 450 460 470 480
480 490 500
pF1KE3 EDDRMKLAAFLESTFLKYRGTQA
XP_016 PGLTRSPSPRGPCRGAAWAGHVGETPAPWGCPPPCAWEHKGPDVPGWHPLGGGRSPASVS
490 500 510 520 530 540
>>XP_016868870 (OMIM: 615563) PREDICTED: nuclear recepto (593 aa)
initn: 3254 init1: 2996 opt: 2996 Z-score: 2165.1 bits: 410.4 E(85289): 7.4e-114
Smith-Waterman score: 3057; 91.3% identity (92.3% similar) in 507 aa overlap (1-475:1-507)
10 20 30 40 50 60
pF1KE3 MAAPEPAPRRAREREREREDESEDESDILEESPCGRWQKRREQVNQGNMPGLQSTFLAMD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MAAPEPAPRRAREREREREDESEDESDILEESPCGRWQKRREQVNQGNMPGLQSTFLAMD
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE3 TEEGVEVVWNELHFGDRKAFAAHEEKIQTVFEQLVLVDHPNIVKLHKYWLDTSEACARVI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TEEGVEVVWNELHFGDRKAFAAHEEKIQTVFEQLVLVDHPNIVKLHKYWLDTSEACARVI
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE3 FITEYVSSGSLKQFLKKTKKNHKAMNARAWKRWCTQILSALSFLHACSPPIIHGNLTSDT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FITEYVSSGSLKQFLKKTKKNHKAMNARAWKRWCTQILSALSFLHACSPPIIHGNLTSDT
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE3 IFIQHNGLIKIGSVWHRIFSNALPDDLRSPIRAEREELRNLHFFPPEYGEVADGTAVDIF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IFIQHNGLIKIGSVWHRIFSNALPDDLRSPIRAEREELRNLHFFPPEYGEVADGTAVDIF
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE3 SFGMCALEMAVLEIQTNGDTRVTEEAIARARHSLSDPNMREFILCCLARDPARRPSAHSL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SFGMCALEMAVLEIQTNGDTRVTEEAIARARHSLSDPNMREFILCCLARDPARRPSAHSL
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE3 LFHRVLFEVHSLKLLAAHCFIQHQYLMPENVVEEKTKAMDLHAVLAELPRPRRPPLQWRY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LFHRVLFEVHSLKLLAAHCFIQHQYLMPENVVEEKTKAMDLHAVLAELPRPRRPPLQWRY
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE3 SEVSFMELDKFLEDVRNGIYPLMNFAATRPLGLPRVLAPPPEEVQKAKTPTPEPFDSETR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SEVSFMELDKFLEDVRNGIYPLMNFAATRPLGLPRVLAPPPEEVQKAKTPTPEPFDSETR
370 380 390 400 410 420
430 440
pF1KE3 KVIQMQCNLERSEDKARWH--------------------------------LTLLLVLED
::::::::::::::::::: :::::::::
XP_016 KVIQMQCNLERSEDKARWHVSGAWEGGAAVGKAGAWRSPEPPADHAPPPPQLTLLLVLED
430 440 450 460 470 480
450 460 470 480 490 500
pF1KE3 RLHRQLTYDLLPTDSAQDLASELVHYGFLHEDDRMKLAAFLESTFLKYRGTQA
::::::::::::. .. :. . : :
XP_016 RLHRQLTYDLLPSRLGRGLGRRAVTPGGGWAAASCLALRHCLSGQRPGPRLGARALWLPP
490 500 510 520 530 540
>>NP_001308287 (OMIM: 606010) nuclear receptor-binding p (543 aa)
initn: 1923 init1: 1095 opt: 2029 Z-score: 1472.6 bits: 282.1 E(85289): 2.8e-75
Smith-Waterman score: 2029; 63.4% identity (82.0% similar) in 489 aa overlap (17-496:44-526)
10 20 30 40
pF1KE3 MAAPEPAPRRAREREREREDESEDESDILEESPCGRWQKRREQVNQ
:.:.::::::.:::::::::::::::.:::
NP_001 SDPKVESSSSAPGLTSVSPPVTSTTSAASPEEEEESEDESEILEESPCGRWQKRREEVNQ
20 30 40 50 60 70
50 60 70 80 90 100
pF1KE3 GNMPGLQSTFLAMDTEEGVEVVWNELHFGDRKAFAAHEEKIQTVFEQLVLVDHPNIVKLH
:.::..:..:::::::::::::::..:..:: . .:::...::..:. ..: ::::.:
NP_001 RNVPGIDSAYLAMDTEEGVEVVWNEVQFSERKNYKLQEEKVRAVFDNLIQLEHLNIVKFH
80 90 100 110 120 130
110 120 130 140 150 160
pF1KE3 KYWLDTSEACARVIFITEYVSSGSLKQFLKKTKKNHKAMNARAWKRWCTQILSALSFLHA
::: : .: :::::::::.:::::::::::::::::.:: .::::::::::::::.::.
NP_001 KYWADIKENKARVIFITEYMSSGSLKQFLKKTKKNHKTMNEKAWKRWCTQILSALSYLHS
140 150 160 170 180 190
170 180 190 200 210 220
pF1KE3 CSPPIIHGNLTSDTIFIQHNGLIKIGSVWHRIFSNALPDDLRSPIRAEREELRNLHFFPP
:.::::::::: ::::::::::::::::.::::.:. :: . . ... ::: .::::: :
NP_001 CDPPIIHGNLTCDTIFIQHNGLIKIGSVFHRIFANVAPDTINNHVKTCREEQKNLHFFAP
200 210 220 230 240 250
230 240 250 260 270 280
pF1KE3 EYGEVAD-GTAVDIFSFGMCALEMAVLEIQTNGDTR-VTEEAIARARHSLSDPNMREFIL
:::::.. :::::.::::::::::::::: ::.. : .:::. : . : :: .::::
NP_001 EYGEVTNVTTAVDIYSFGMCALEMAVLEIQGNGESSYVPQEAISSAIQLLEDPLQREFIQ
260 270 280 290 300 310
290 300 310 320 330 340
pF1KE3 CCLARDPARRPSAHSLLFHRVLFEVHSLKLLAAHCFIQHQYLMPENVVEEKTKAMDLHAV
:: .:::::.:. :::: .:::: :::::::::.. ::...:::..:: :: :: ::
NP_001 KCLQSEPARRPTARELLFHPALFEVPSLKLLAAHCIVGHQHMIPENALEEITKNMDTSAV
320 330 340 350 360 370
350 360 370 380 390 400
pF1KE3 LAELPR-PRRPPLQWRYSEVSFMELDKFLEDVRNGIYPLMNFAATRPLGLPRVLAPPPEE
:::.: : : :.: ::. .:::::::::::::::: : :::: : ::
NP_001 LAEIPAGPGREPVQTLYSQSPALELDKFLEDVRNGIYPLTAF------GLPRPQQPQQEE
380 390 400 410 420
410 420 430 440 450
pF1KE3 VQK------AKTPTPEPFDSETRKVIQMQCNLERSEDKARWHLTLLLVLEDRLHRQLTYD
: . .::::::: . :::::. ::::.: :. .. :::::: :::.:.:.:. :
NP_001 VTSPVVPPSVKTPTPEPAEVETRKVVLMQCNIESVEEGVKHHLTLLLKLEDKLNRHLSCD
430 440 450 460 470 480
460 470 480 490 500
pF1KE3 LLPTDSAQDLASELVHYGFLHEDDRMKLAAFLESTFLKYRGTQA
:.:... .::.:::. ::. : :. .:...:: :. :.
NP_001 LMPNENIPELAAELVQLGFISEADQSRLTSLLEETLNKFNFARNSTLNSAAVTVSS
490 500 510 520 530 540
>>NP_001308288 (OMIM: 606010) nuclear receptor-binding p (543 aa)
initn: 1923 init1: 1095 opt: 2029 Z-score: 1472.6 bits: 282.1 E(85289): 2.8e-75
Smith-Waterman score: 2029; 63.4% identity (82.0% similar) in 489 aa overlap (17-496:44-526)
10 20 30 40
pF1KE3 MAAPEPAPRRAREREREREDESEDESDILEESPCGRWQKRREQVNQ
:.:.::::::.:::::::::::::::.:::
NP_001 SDPKVESSSSAPGLTSVSPPVTSTTSAASPEEEEESEDESEILEESPCGRWQKRREEVNQ
20 30 40 50 60 70
50 60 70 80 90 100
pF1KE3 GNMPGLQSTFLAMDTEEGVEVVWNELHFGDRKAFAAHEEKIQTVFEQLVLVDHPNIVKLH
:.::..:..:::::::::::::::..:..:: . .:::...::..:. ..: ::::.:
NP_001 RNVPGIDSAYLAMDTEEGVEVVWNEVQFSERKNYKLQEEKVRAVFDNLIQLEHLNIVKFH
80 90 100 110 120 130
110 120 130 140 150 160
pF1KE3 KYWLDTSEACARVIFITEYVSSGSLKQFLKKTKKNHKAMNARAWKRWCTQILSALSFLHA
::: : .: :::::::::.:::::::::::::::::.:: .::::::::::::::.::.
NP_001 KYWADIKENKARVIFITEYMSSGSLKQFLKKTKKNHKTMNEKAWKRWCTQILSALSYLHS
140 150 160 170 180 190
170 180 190 200 210 220
pF1KE3 CSPPIIHGNLTSDTIFIQHNGLIKIGSVWHRIFSNALPDDLRSPIRAEREELRNLHFFPP
:.::::::::: ::::::::::::::::.::::.:. :: . . ... ::: .::::: :
NP_001 CDPPIIHGNLTCDTIFIQHNGLIKIGSVFHRIFANVAPDTINNHVKTCREEQKNLHFFAP
200 210 220 230 240 250
230 240 250 260 270 280
pF1KE3 EYGEVAD-GTAVDIFSFGMCALEMAVLEIQTNGDTR-VTEEAIARARHSLSDPNMREFIL
:::::.. :::::.::::::::::::::: ::.. : .:::. : . : :: .::::
NP_001 EYGEVTNVTTAVDIYSFGMCALEMAVLEIQGNGESSYVPQEAISSAIQLLEDPLQREFIQ
260 270 280 290 300 310
290 300 310 320 330 340
pF1KE3 CCLARDPARRPSAHSLLFHRVLFEVHSLKLLAAHCFIQHQYLMPENVVEEKTKAMDLHAV
:: .:::::.:. :::: .:::: :::::::::.. ::...:::..:: :: :: ::
NP_001 KCLQSEPARRPTARELLFHPALFEVPSLKLLAAHCIVGHQHMIPENALEEITKNMDTSAV
320 330 340 350 360 370
350 360 370 380 390 400
pF1KE3 LAELPR-PRRPPLQWRYSEVSFMELDKFLEDVRNGIYPLMNFAATRPLGLPRVLAPPPEE
:::.: : : :.: ::. .:::::::::::::::: : :::: : ::
NP_001 LAEIPAGPGREPVQTLYSQSPALELDKFLEDVRNGIYPLTAF------GLPRPQQPQQEE
380 390 400 410 420
410 420 430 440 450
pF1KE3 VQK------AKTPTPEPFDSETRKVIQMQCNLERSEDKARWHLTLLLVLEDRLHRQLTYD
: . .::::::: . :::::. ::::.: :. .. :::::: :::.:.:.:. :
NP_001 VTSPVVPPSVKTPTPEPAEVETRKVVLMQCNIESVEEGVKHHLTLLLKLEDKLNRHLSCD
430 440 450 460 470 480
460 470 480 490 500
pF1KE3 LLPTDSAQDLASELVHYGFLHEDDRMKLAAFLESTFLKYRGTQA
:.:... .::.:::. ::. : :. .:...:: :. :.
NP_001 LMPNENIPELAAELVQLGFISEADQSRLTSLLEETLNKFNFARNSTLNSAAVTVSS
490 500 510 520 530 540
>>NP_001308290 (OMIM: 606010) nuclear receptor-binding p (542 aa)
initn: 1567 init1: 1109 opt: 2012 Z-score: 1460.4 bits: 279.9 E(85289): 1.3e-74
Smith-Waterman score: 2012; 63.0% identity (82.0% similar) in 489 aa overlap (17-496:44-525)
10 20 30 40
pF1KE3 MAAPEPAPRRAREREREREDESEDESDILEESPCGRWQKRREQVNQ
:.:.::::::.:::::::::::::::.:::
NP_001 SDPKVESSSSAPGLTSVSPPVTSTTSAASPEEEEESEDESEILEESPCGRWQKRREEVNQ
20 30 40 50 60 70
50 60 70 80 90 100
pF1KE3 GNMPGLQSTFLAMDTEEGVEVVWNELHFGDRKAFAAHEEKIQTVFEQLVLVDHPNIVKLH
:.::..:..:::::::::::::::..:..:: . .:::...::..:. ..: ::::.:
NP_001 RNVPGIDSAYLAMDTEEGVEVVWNEVQFSERKNYKLQEEKVRAVFDNLIQLEHLNIVKFH
80 90 100 110 120 130
110 120 130 140 150 160
pF1KE3 KYWLDTSEACARVIFITEYVSSGSLKQFLKKTKKNHKAMNARAWKRWCTQILSALSFLHA
::: : .: :::::::::.:::::::::::::::::.:: .::::::::::::::.::.
NP_001 KYWADIKENKARVIFITEYMSSGSLKQFLKKTKKNHKTMNEKAWKRWCTQILSALSYLHS
140 150 160 170 180 190
170 180 190 200 210 220
pF1KE3 CSPPIIHGNLTSDTIFIQHNGLIKIGSVWHRIFSNALPDDLRSPIRAEREELRNLHFFPP
:.::::::::: ::::::::::::::::.::::.:. :: . . ... ::: .::::: :
NP_001 CDPPIIHGNLTCDTIFIQHNGLIKIGSVFHRIFANVAPDTINNHVKTCREEQKNLHFFAP
200 210 220 230 240 250
230 240 250 260 270 280
pF1KE3 EYGEVAD-GTAVDIFSFGMCALEMAVLEIQTNGDTR-VTEEAIARARHSLSDPNMREFIL
:::::.. :::::.::::::::::::::: ::.. : .:::. : . : :: ...::
NP_001 EYGEVTNVTTAVDIYSFGMCALEMAVLEIQGNGESSYVPQEAISSAIQLLEDP-LQRFIQ
260 270 280 290 300 310
290 300 310 320 330 340
pF1KE3 CCLARDPARRPSAHSLLFHRVLFEVHSLKLLAAHCFIQHQYLMPENVVEEKTKAMDLHAV
:: .:::::.:. :::: .:::: :::::::::.. ::...:::..:: :: :: ::
NP_001 KCLQSEPARRPTARELLFHPALFEVPSLKLLAAHCIVGHQHMIPENALEEITKNMDTSAV
320 330 340 350 360 370
350 360 370 380 390 400
pF1KE3 LAELPR-PRRPPLQWRYSEVSFMELDKFLEDVRNGIYPLMNFAATRPLGLPRVLAPPPEE
:::.: : : :.: ::. .:::::::::::::::: : :::: : ::
NP_001 LAEIPAGPGREPVQTLYSQSPALELDKFLEDVRNGIYPLTAF------GLPRPQQPQQEE
380 390 400 410 420
410 420 430 440 450
pF1KE3 VQK------AKTPTPEPFDSETRKVIQMQCNLERSEDKARWHLTLLLVLEDRLHRQLTYD
: . .::::::: . :::::. ::::.: :. .. :::::: :::.:.:.:. :
NP_001 VTSPVVPPSVKTPTPEPAEVETRKVVLMQCNIESVEEGVKHHLTLLLKLEDKLNRHLSCD
430 440 450 460 470 480
460 470 480 490 500
pF1KE3 LLPTDSAQDLASELVHYGFLHEDDRMKLAAFLESTFLKYRGTQA
:.:... .::.:::. ::. : :. .:...:: :. :.
NP_001 LMPNENIPELAAELVQLGFISEADQSRLTSLLEETLNKFNFARNSTLNSAAVTVSS
490 500 510 520 530 540
501 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sun Nov 6 01:40:12 2016 done: Sun Nov 6 01:40:13 2016
Total Scan time: 10.360 Total Display time: 0.100
Function used was FASTA [36.3.4 Apr, 2011]