Result of FASTA (ccds) for
pFN21AE5568
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE5568, 431 aa
1>>>pF1KE5568 431 - 431 aa - 431 aa
Library: human.CCDS.faa
18511270 residues in 32554 sequences
Statistics: Expectation_n fit: rho(ln(x))= 9.3254+/-0.000932; mu= 0.4480+/- 0.056
mean_var=228.4081+/-45.811, 0's: 0 Z-trim(113.9): 10 B-trim: 136 in 1/50
Lambda= 0.084863
statistics sampled from 14488 (14497) to 14488 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.769), E-opt: 0.2 (0.445), width: 16
Scan time: 3.010
The best scores are: opt bits E(32554)
CCDS33249.1 ASTL gene_id:431705|Hs108|chr2 ( 431) 2947 373.3 2.5e-103
CCDS77173.1 MEP1B gene_id:4225|Hs108|chr18 ( 700) 464 69.5 1.2e-11
CCDS45846.1 MEP1B gene_id:4225|Hs108|chr18 ( 701) 464 69.5 1.2e-11
CCDS34856.1 BMP1 gene_id:649|Hs108|chr8 ( 730) 446 67.3 5.7e-11
CCDS7449.1 TLL2 gene_id:7093|Hs108|chr10 (1015) 449 67.8 5.7e-11
CCDS6026.1 BMP1 gene_id:649|Hs108|chr8 ( 986) 446 67.4 7.2e-11
CCDS56342.1 TLL1 gene_id:7092|Hs108|chr4 ( 392) 435 65.8 8.9e-11
>>CCDS33249.1 ASTL gene_id:431705|Hs108|chr2 (431 aa)
initn: 2947 init1: 2947 opt: 2947 Z-score: 1968.5 bits: 373.3 E(32554): 2.5e-103
Smith-Waterman score: 2947; 99.5% identity (100.0% similar) in 431 aa overlap (1-431:1-431)
10 20 30 40 50 60
pF1KE5 MEGVGGLWPWVLGLLSLPGVILGAPLASSCAGACGTSFPDGLTPEGTQASGDKDIPAINQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS33 MEGVGGLWPWVLGLLSLPGVILGAPLASSCAGACGTSFPDGLTPEGTQASGDKDIPAINQ
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE5 GLILEETPESSFLIEGDIIRPSPFRLLSATSNKWPMGGSGVVEVPFLLSSKYDEPSRQVI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS33 GLILEETPESSFLIEGDIIRPSPFRLLSATSNKWPMGGSGVVEVPFLLSSKYDEPSRQVI
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE5 LEALAEFERSTCIRFVTYQDQRDFISIIPMYGCFSSVGRSGGMQVVSLAPTCLQKGRGIV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS33 LEALAEFERSTCIRFVTYQDQRDFISIIPMYGCFSSVGRSGGMQVVSLAPTCLQKGRGIV
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE5 LHELMHVLGFWHEHTRADRDRYIRVNWNEILPGFEINFIKSRSSNMLTPYDYSSVMHYGR
:::::::::::::::::::::::::::::::::::::::::.::::::::::::::::::
CCDS33 LHELMHVLGFWHEHTRADRDRYIRVNWNEILPGFEINFIKSQSSNMLTPYDYSSVMHYGR
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE5 LAFSRRGLPTITPLWAPSVHIGQRWNLSASDITRVLQLYGCSPSGPRPRGRGSHAHSTGR
::::::::::::::::::::::::::::::::::::.:::::::::::::::::::::::
CCDS33 LAFSRRGLPTITPLWAPSVHIGQRWNLSASDITRVLKLYGCSPSGPRPRGRGSHAHSTGR
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE5 SPAPASLSLQRLLEALSAESRSPDPSGSSAGGQPVPAGPGESPHGWESPALKKLSAEASA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS33 SPAPASLSLQRLLEALSAESRSPDPSGSSAGGQPVPAGPGESPHGWESPALKKLSAEASA
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE5 RQPQTLASSPRSRPGAGAPGVAQEQSWLAGVSTKPTVPSSEAGIQPVPVQGSPALPGGCV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS33 RQPQTLASSPRSRPGAGAPGVAQEQSWLAGVSTKPTVPSSEAGIQPVPVQGSPALPGGCV
370 380 390 400 410 420
430
pF1KE5 PRNHFKGMSED
:::::::::::
CCDS33 PRNHFKGMSED
430
>>CCDS77173.1 MEP1B gene_id:4225|Hs108|chr18 (700 aa)
initn: 462 init1: 186 opt: 464 Z-score: 322.6 bits: 69.5 E(32554): 1.2e-11
Smith-Waterman score: 501; 37.8% identity (63.8% similar) in 254 aa overlap (41-284:20-258)
20 30 40 50 60
pF1KE5 VLGLLSLPGVILGAPLASSCAGACGTSFPDGL-TPEGTQASG--DKDIPAINQGLILEET
:: :::. ...: :.:: ::.:: :.
CCDS77 MDLWNLSWFLFLDALLVISGLATPENFDVDGGMDQDIFDINEGLGLD--
10 20 30 40
70 80 90 100 110 120
pF1KE5 PESSFLIEGDII--RPSPFRLLSATSNKWPMGGSGVVEVPFLLSSKYDEPSRQVILEALA
:.:::: : . . . . .:: .:..: .. . .. :::.:.
CCDS77 -----LFEGDIRLDRAQIRNSIIGEKYRWPH------TIPYVLEDSLEMNAKGVILNAFE
50 60 70 80 90
130 140 150 160 170 180
pF1KE5 EFERSTCIRFVTYQDQRDFISIIPMYGCFSSVG-RSGGMQVVSLAPTCLQKGRGIVLHEL
... .::: : . . ..::.. ::.:::: : : : .:.. .: . . : ::.
CCDS77 RYRLKTCIDFKPWAGETNYISVFKGSGCWSSVGNRRVGKQELSIGANCDRIAT--VQHEF
100 110 120 130 140 150
190 200 210 220 230 240
pF1KE5 MHVLGFWHEHTRADRDRYIRVNWNEILPGFEINFIKSR---SSNMLTPYDYSSVMHYGRL
.:.::::::..:.::: :.:. :..:: : : :: :... .::::.:::::..
CCDS77 LHALGFWHEQSRSDRDDYVRIMWDRILSGREHNFNTYSDDISDSLNVPYDYTSVMHYSKT
160 170 180 190 200 210
250 260 270 280 290 300
pF1KE5 AFSRRGLPTITPLWAPSVH-IGQRWNLSASDITRVLQLYGCSPSGPRPRGRGSHAHSTGR
::. :::. . :::: ..: ::. .. :::.:: :
CCDS77 AFQNGTEPTIVTRISDFEDVIGQRMDFSDSDLLKLNQLYNCSSSLSFMDSCSFELENVCG
220 230 240 250 260 270
310 320 330 340 350 360
pF1KE5 SPAPASLSLQRLLEALSAESRSPDPSGSSAGGQPVPAGPGESPHGWESPALKKLSAEASA
CCDS77 MIQSSGDNADWQRVSQVPRGPESDHSNMGQCQGSGFFMHFDSSSVNVGATAVLESRTLYP
280 290 300 310 320 330
>>CCDS45846.1 MEP1B gene_id:4225|Hs108|chr18 (701 aa)
initn: 462 init1: 186 opt: 464 Z-score: 322.6 bits: 69.5 E(32554): 1.2e-11
Smith-Waterman score: 501; 37.8% identity (63.8% similar) in 254 aa overlap (41-284:20-258)
20 30 40 50 60
pF1KE5 VLGLLSLPGVILGAPLASSCAGACGTSFPDGL-TPEGTQASG--DKDIPAINQGLILEET
:: :::. ...: :.:: ::.:: :.
CCDS45 MDLWNLSWFLFLDALLVISGLATPENFDVDGGMDQDIFDINEGLGLD--
10 20 30 40
70 80 90 100 110 120
pF1KE5 PESSFLIEGDII--RPSPFRLLSATSNKWPMGGSGVVEVPFLLSSKYDEPSRQVILEALA
:.:::: : . . . . .:: .:..: .. . .. :::.:.
CCDS45 -----LFEGDIRLDRAQIRNSIIGEKYRWPH------TIPYVLEDSLEMNAKGVILNAFE
50 60 70 80 90
130 140 150 160 170 180
pF1KE5 EFERSTCIRFVTYQDQRDFISIIPMYGCFSSVG-RSGGMQVVSLAPTCLQKGRGIVLHEL
... .::: : . . ..::.. ::.:::: : : : .:.. .: . . : ::.
CCDS45 RYRLKTCIDFKPWAGETNYISVFKGSGCWSSVGNRRVGKQELSIGANCDRIAT--VQHEF
100 110 120 130 140 150
190 200 210 220 230 240
pF1KE5 MHVLGFWHEHTRADRDRYIRVNWNEILPGFEINFIKSR---SSNMLTPYDYSSVMHYGRL
.:.::::::..:.::: :.:. :..:: : : :: :... .::::.:::::..
CCDS45 LHALGFWHEQSRSDRDDYVRIMWDRILSGREHNFNTYSDDISDSLNVPYDYTSVMHYSKT
160 170 180 190 200 210
250 260 270 280 290 300
pF1KE5 AFSRRGLPTITPLWAPSVH-IGQRWNLSASDITRVLQLYGCSPSGPRPRGRGSHAHSTGR
::. :::. . :::: ..: ::. .. :::.:: :
CCDS45 AFQNGTEPTIVTRISDFEDVIGQRMDFSDSDLLKLNQLYNCSSSLSFMDSCSFELENVCG
220 230 240 250 260 270
310 320 330 340 350 360
pF1KE5 SPAPASLSLQRLLEALSAESRSPDPSGSSAGGQPVPAGPGESPHGWESPALKKLSAEASA
CCDS45 MIQSSGDNADWQRVSQVPRGPESDHSNMGQCQGSGFFMHFDSSSVNVGATAVLESRTLYP
280 290 300 310 320 330
>>CCDS34856.1 BMP1 gene_id:649|Hs108|chr8 (730 aa)
initn: 398 init1: 245 opt: 446 Z-score: 310.4 bits: 67.3 E(32554): 5.7e-11
Smith-Waterman score: 449; 38.1% identity (64.1% similar) in 231 aa overlap (94-300:130-351)
70 80 90 100 110 120
pF1KE5 LEETPESSFLIEGDIIRPSPFRLLSATSNKWPMGGSGVVEVPFLLSSKYDEPSRQVILEA
:: .::. ::...... .: :. .:
CCDS34 TNGQPQRGACGRWRGRSRSRRAATSRPERVWP---DGVI--PFVIGGNFTGSQRAVFRQA
100 110 120 130 140 150
130 140 150 160 170 180
pF1KE5 LAEFERSTCIRFVTYQDQRDFISII--PMYGCFSSVGR-SGGMQVVSLAPTCLQKGRGIV
. ..:. ::. :. :. ..: . : :: : ::: .:: :..:.. .: . :::
CCDS34 MRHWEKHTCVTFLERTDEDSYIVFTYRPC-GCCSYVGRRGGGPQAISIGKNCDK--FGIV
160 170 180 190 200 210
190 200 210 220 230
pF1KE5 LHELMHVLGFWHEHTRADRDRYIRVNWNEILPGFEINFIKSRSSNMLT---PYDYSSVMH
.::: ::.:::::::: ::::.. . ..: :: : ::.: . ... . ::..:.::
CCDS34 VHELGHVVGFWHEHTRPDRDRHVSIVRENIQPGQEYNFLKMEPQEVESLGETYDFDSIMH
220 230 240 250 260 270
240 250 260 270 280
pF1KE5 YGRLAFSRRG--LPTITPLW-APSVH--IGQRWNLSASDITRVLQLYGCSPSG-------
:.: .::: : : ::.: . . .:. :::: :: .::... .:: : :
CCDS34 YARNTFSR-GIFLDTIVPKYEVNGVKPPIGQRTRLSKGDIAQARKLYKCPACGETLQDST
280 290 300 310 320 330
290 300 310 320 330
pF1KE5 -----PR-PRGRGSHAHSTGRSPAPASLSLQRLLEALSAESRSPDPSGSSAGGQPVPAGP
:. : : ..: : . :
CCDS34 GNFSSPEYPNGYSAHMHCVWRISVTPGEKIILNFTSLDLYRSRLCWYDYVEVRDGFWRKA
340 350 360 370 380 390
>>CCDS7449.1 TLL2 gene_id:7093|Hs108|chr10 (1015 aa)
initn: 342 init1: 219 opt: 449 Z-score: 310.4 bits: 67.8 E(32554): 5.7e-11
Smith-Waterman score: 450; 35.2% identity (62.5% similar) in 261 aa overlap (37-285:105-352)
10 20 30 40 50 60
pF1KE5 LWPWVLGLLSLPGVILGAPLASSCAGACGTSFPDGLTPE-GTQASGDKDIPAINQGLILE
: :: . . ::. .: :: .. :
CCDS74 FHIDKARDWTKQTVGATGHSTGGLEEQASESSPDTTAMDTGTKEAG-KDG---RENTTLL
80 90 100 110 120 130
70 80 90 100 110 120
pF1KE5 ETPESSFLIEGDIIRPSPFRLLSATSNK-WPMGGSGVVEVPFLLSSKYDEPSRQVILEAL
..: ... . . : : .. ... :: :: .:....... .: .. .:.
CCDS74 HSP-GTLHAAAKTFSPRVRRATTSRTERIWP-GGV----IPYVIGGNFTGSQRAIFKQAM
140 150 160 170 180
130 140 150 160 170 180
pF1KE5 AEFERSTCIRFVTYQDQRDFISI-IPMYGCFSSVGR-SGGMQVVSLAPTCLQKGRGIVLH
..:. ::. :. :...:: . :: : ::: .:: :..:.. .: . ::: :
CCDS74 RHWEKHTCVTFIERTDEESFIVFSYRTCGCCSYVGRRGGGPQAISIGKNCDK--FGIVAH
190 200 210 220 230 240
190 200 210 220 230
pF1KE5 ELMHVLGFWHEHTRADRDRYIRVNWNEILPGFEINFIKSRS---SNMLTPYDYSSVMHYG
:: ::.:::::::: :::... . ..: :: : ::.: .. :.. ::..:.:::.
CCDS74 ELGHVVGFWHEHTRPDRDQHVTIIRENIQPGQEYNFLKMEAGEVSSLGETYDFDSIMHYA
250 260 270 280 290 300
240 250 260 270 280 290
pF1KE5 RLAFSRRG--LPTITPLWAPS-VH--IGQRWNLSASDITRVLQLYGCSPSGPRPRGRGSH
: .::: : : :: : . :. :::: :: .::... .:: : :
CCDS74 RNTFSR-GVFLDTILPRQDDNGVRPTIGQRVRLSQGDIAQARKLYKCPACGETLQDTTGN
310 320 330 340 350 360
300 310 320 330 340 350
pF1KE5 AHSTGRSPAPASLSLQRLLEALSAESRSPDPSGSSAGGQPVPAGPGESPHGWESPALKKL
CCDS74 FSAPGFPNGYPSYSHCVWRISVTPGEKIVLNFTSMDLFKSRLCWYDYVEVRDGYWRKAPL
370 380 390 400 410 420
>>CCDS6026.1 BMP1 gene_id:649|Hs108|chr8 (986 aa)
initn: 398 init1: 245 opt: 446 Z-score: 308.6 bits: 67.4 E(32554): 7.2e-11
Smith-Waterman score: 449; 38.1% identity (64.1% similar) in 231 aa overlap (94-300:130-351)
70 80 90 100 110 120
pF1KE5 LEETPESSFLIEGDIIRPSPFRLLSATSNKWPMGGSGVVEVPFLLSSKYDEPSRQVILEA
:: .::. ::...... .: :. .:
CCDS60 TNGQPQRGACGRWRGRSRSRRAATSRPERVWP---DGVI--PFVIGGNFTGSQRAVFRQA
100 110 120 130 140 150
130 140 150 160 170 180
pF1KE5 LAEFERSTCIRFVTYQDQRDFISII--PMYGCFSSVGR-SGGMQVVSLAPTCLQKGRGIV
. ..:. ::. :. :. ..: . : :: : ::: .:: :..:.. .: . :::
CCDS60 MRHWEKHTCVTFLERTDEDSYIVFTYRPC-GCCSYVGRRGGGPQAISIGKNCDK--FGIV
160 170 180 190 200 210
190 200 210 220 230
pF1KE5 LHELMHVLGFWHEHTRADRDRYIRVNWNEILPGFEINFIKSRSSNMLT---PYDYSSVMH
.::: ::.:::::::: ::::.. . ..: :: : ::.: . ... . ::..:.::
CCDS60 VHELGHVVGFWHEHTRPDRDRHVSIVRENIQPGQEYNFLKMEPQEVESLGETYDFDSIMH
220 230 240 250 260 270
240 250 260 270 280
pF1KE5 YGRLAFSRRG--LPTITPLW-APSVH--IGQRWNLSASDITRVLQLYGCSPSG-------
:.: .::: : : ::.: . . .:. :::: :: .::... .:: : :
CCDS60 YARNTFSR-GIFLDTIVPKYEVNGVKPPIGQRTRLSKGDIAQARKLYKCPACGETLQDST
280 290 300 310 320 330
290 300 310 320 330
pF1KE5 -----PR-PRGRGSHAHSTGRSPAPASLSLQRLLEALSAESRSPDPSGSSAGGQPVPAGP
:. : : ..: : . :
CCDS60 GNFSSPEYPNGYSAHMHCVWRISVTPGEKIILNFTSLDLYRSRLCWYDYVEVRDGFWRKA
340 350 360 370 380 390
>>CCDS56342.1 TLL1 gene_id:7092|Hs108|chr4 (392 aa)
initn: 349 init1: 192 opt: 435 Z-score: 307.0 bits: 65.8 E(32554): 8.9e-11
Smith-Waterman score: 435; 36.4% identity (61.8% similar) in 228 aa overlap (83-299:146-364)
60 70 80 90 100 110
pF1KE5 KDIPAINQGLILEETPESSFLIEGDIIRPSPFRLLSATSNKWPMGGSGVVEVPFLLSSKY
: : : :: :: .:.......
CCDS56 RRIGFGLEQNNTVKGKVPLQFSGQNEKNRVPRAATSRTERIWP-GGV----IPYVIGGNF
120 130 140 150 160 170
120 130 140 150 160
pF1KE5 DEPSRQVILEALAEFERSTCIRFVTYQDQRDFISII--PMYGCFSSVGRSG-GMQVVSLA
.: .. .:. ..:. ::. :. .:....: . : :: : ::: : : :..:..
CCDS56 TGSQRAMFKQAMRHWEKHTCVTFIERSDEESYIVFTYRPC-GCCSYVGRRGNGPQAISIG
180 190 200 210 220
170 180 190 200 210 220
pF1KE5 PTCLQKGRGIVLHELMHVLGFWHEHTRADRDRYIRVNWNEILPGFEINFIK---SRSSNM
.: . :::.::: ::.:::::::: ::: .. . ..: :: : ::.: .. ...
CCDS56 KNCDK--FGIVVHELGHVIGFWHEHTRPDRDNHVTIIRENIQPGQEYNFLKMEPGEVNSL
230 240 250 260 270 280
230 240 250 260 270 280
pF1KE5 LTPYDYSSVMHYGRLAFSRRG--LPTITPLWAPS---VHIGQRWNLSASDITRVLQLYGC
::..:.:::.: .::: : : :: : . :::: :: .::... .:: :
CCDS56 GERYDFDSIMHYARNTFSR-GMFLDTILPSRDDNGIRPAIGQRTRLSKGDIAQARKLYRC
290 300 310 320 330 340
290 300 310 320 330 340
pF1KE5 SPSGPRPRGRGSHAHSTGRSPAPASLSLQRLLEALSAESRSPDPSGSSAGGQPVPAGPGE
: . ... : :
CCDS56 PACGETLQESNGNLSSPGFPNGYPSYTHCIWRVSVTPGEKVVFSLC
350 360 370 380 390
431 residues in 1 query sequences
18511270 residues in 32554 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Tue Nov 8 01:55:09 2016 done: Tue Nov 8 01:55:09 2016
Total Scan time: 3.010 Total Display time: 0.030
Function used was FASTA [36.3.4 Apr, 2011]